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Fluorescent Dye patents



      
           
This page is updated frequently with new Fluorescent Dye-related patent applications. Subscribe to the Fluorescent Dye RSS feed to automatically get the update: related Fluorescent RSS feeds. RSS updates for this page: Fluorescent Dye RSS RSS


Date/App# patent app List of recent Fluorescent Dye-related patents
06/25/15
20150177255
 Novel fluorescent dyes, labeled conjugates and analytical methods patent thumbnailnew patent Novel fluorescent dyes, labeled conjugates and analytical methods
There are described novel fluorescent dyes, conjugates which include a radical of a dye and a biological or a synthetic moiety and diagnostic and in vivo assays utilizing such conjugates and other products including the dyes and conjugates.. .
Scintillon Research Llc
06/25/15
20150176060
 Method for coding of multiple pcr reactions for assay recognition patent thumbnailnew patent Method for coding of multiple pcr reactions for assay recognition
The present invention provides for methods and compositions that use fluorescent dyes for the identification of reagents and solutions that are used to perform pcr assays.. .
Roche Molecular Systems, Inc.
05/21/15
20150139527
 Image processing apparatus and image processing method patent thumbnailImage processing apparatus and image processing method
An image processing apparatus includes: an interface unit configured to input an image signal from an imaging apparatus that exposes a specimen dyed with a fluorescent dye to excitation light and images fluorescence by a color imaging element; and a color correction circuit configured to retain information on a percentage of each of a component of a second color and a component of a third color with respect to a component of a first color corresponding to the excitation light in the image signal, which is determined in advance based on color filter spectral characteristics of the color imaging element, and reduce each of an amount corresponding to the percentage of the component of the second color and an amount corresponding to the percentage of the component of the third color from the input image signal.. .
Sony Corporation
04/30/15
20150119708
 Devices and systems for fluorescence imaging of tissue patent thumbnailDevices and systems for fluorescence imaging of tissue
A system and method for fluorescence imaging of tissue in vivo and in situ, e.g., for minimally invasive diagnosis of patients. A fluorescent imaging system is provided that has a dye carrier coupled to the distal end of a probe containing a fiber optics bundle, which allows for the introduction of at least one fluorescent dye therein the dye carrier into a portion of the tissue of interest of a subject or patient when the dye carrier is selectively brought into contact with the portion of the tissue of interest.
University Of Utah Research Foundation
04/30/15
20150118703
 Class of cyano-substituted asymmetric cyanine dyes, synthesizing method and application thereof patent thumbnailClass of cyano-substituted asymmetric cyanine dyes, synthesizing method and application thereof
The present invention provides a category of cyano-substituted asymmetric cyanine dyes having the following general structural formula i and its synthesizing method. The cyano-substituted asymmetric cyanine dyes in present invention are easily synthesized and have long emission wavelength, high molar extinction coefficient, high sensitivity, good light stability, high fluorescence quantum yield after binding with nucleic acid, and low cell toxicity, which is beneficial for application as fluorescent dyes and could also be used in the field of identifying nucleic acid molecules, clinical diagnostics, and immunoassay testing etc..
Dalian University Of Technology
04/30/15
20150118162
 Two-photon fluorescent probes for imaging of total sulfide in live cell and tissue, and quantitative estimation of total sulfide concentration using the same patent thumbnailTwo-photon fluorescent probes for imaging of total sulfide in live cell and tissue, and quantitative estimation of total sulfide concentration using the same
The present disclosure relates to a two-photon fluorescent dye for imaging total sulfide in vivo and a method for quantitatively estimating total sulfide concentration in vivo using the same. The two-photon fluorescent dye, which includes a compound of [chemical formula 1], can detect hydrosulfide on and image total sulfide and allows quantitative estimation of total sulfide concentration in vivo..
Korea University Research And Business Foundation
04/23/15
20150112193
 Method for assessing perfusion in tissue patent thumbnailMethod for assessing perfusion in tissue
Methods for assessing perfusion in a portion of tissue in an animal may include administering a fluorescent dye to the animal such that the fluorescent dye enters the portion of tissue, exciting the fluorescent dye within the portion of tissue with a source of illumination such that the fluorescent dye emits radiation, capturing the radiation emitted by the fluorescent dye with a camera, and obtaining at least one image of the fluorescence radiation emitted from the portion of tissue. .
National Research Council Of Canada
04/23/15
20150112192
 Method for assessing blood flow in vasculature patent thumbnailMethod for assessing blood flow in vasculature
Methods for assessing blood flow in vasculature in a portion of tissue in an animal may include administering a fluorescent dye to the animal such that the fluorescent dye enters the portion of tissue, exciting the fluorescent dye within the portion of tissue with a source of illumination such that the fluorescent dye emits radiation, capturing the radiation emitted by the fluorescent dye with a camera capable of capturing a series of angiographic images within the portion of tissue, and evaluating the series of angiographic images to assess blood flow in the vasculature in the tissue portion.. .
National Research Council Of Canada
04/16/15
20150104394
 Characterization of biological tissues at a cellular level using red and far-red fluorescent dyes patent thumbnailCharacterization of biological tissues at a cellular level using red and far-red fluorescent dyes
A method for observing the morphology of a biological tissue is disclosed. The method involves using a fluorescent dye on the biological tissue, where the fluorescent dye is selected from patent blue v, isosulfan blue, toluidine blue, hypericin, indocyanine green, mvac, or doxorubicin, and using a microscopic linear or non-linear imaging system to form an image of the biological tissue, where the fluorescence of the dye reveals the morphology of the tissue at cellular scale..
Igr-institut Gustave Roussy
04/02/15
20150093833
 Method of pre-treating a filter used in a small-scale water separometer patent thumbnailMethod of pre-treating a filter used in a small-scale water separometer
The safety and proper performance of jet aircraft engines requires that any contamination of jet fuel, for example by water or by improper contaminants, be filtered (removed) before delivery of the fuel, through hoses, to the fuel tanks of the aircraft. Coalescing devices and filters in the fuel delivery system are used to attain this result.
D-2, Inc.
04/02/15
20150093777

Methods for determining and/or monitoring conditions of a three dimensional cell culture system and optical sensor device for conducting said methods


A method for at least one of determining and monitoring at least one condition of/in a three dimensional cell culture system comprising at least one growth section, the at least one condition being selected from the group consisting of a physiological condition, a vitality, and a metabolism status, the method includes determining the physiological condition using erythrocytes as detectors, determining and/or monitoring the vitality by measuring living cell fluorescent dyes, and determining and/or monitoring the metabolism status by at least one of measuring an autofluorescence of nadh and/or fad, by determining a nadh/nad+ ratio, and by determining a nadh/fad ratio.. .
Tissuse Gmbh
04/02/15
20150090012

System for pre-treating a filter used in a small-scale water separometer


The safety and proper performance of jet aircraft engines requires that any contamination of jet fuel, for example by water or by improper contaminants, be filtered (removed) before delivery of the fuel, through hoses, to the fuel tanks of the aircraft. Coalescing devices and filters in the fuel delivery system are used to attain this result.
D-2, Inc.
03/12/15
20150073273

Fluorescence detection device


A fluorescence detection device comprises: a plurality of light sources that apply an excitation light from an outside of a living body toward fluorescent dye previously injected into the living body; and a plurality of detectors that detect fluorescence emitted from the fluorescent dye by the excitation light, and output the detected fluorescence as an electric signal. The plurality of light sources and the plurality of detectors are arranged in at least one line.
Hamamatsu Photonics K.k.
03/05/15
20150064800

Diagnostic devices, methods and systems for detecting platelet factor 4 (pf4)/heparin antibodies


The present invention provides a novel assay for detecting human antibodies specific for a platelet factor 4 (pf4)/heparin complex in a fluid sample. The assay utilizes an immobilized pf4/polyanion complex and an anti-human antibody conjugated to a non-particulate fluorescent dye to capture and detect human pf4/heparin antibodies.
02/26/15
20150056632

Fluorescent dyes, fluorescent dye kits, and methods of preparing labeled molecules


The present invention provides methods, compositions, and kits useful in preparing labeled molecules, which are useful in the detection of binding partners.. .
Biotium, Inc.
02/19/15
20150050659

Protected fluorescent reagent compounds


Protected fluorescent reagent compounds and their methods of synthesis are provided. The compounds are useful in various fluorescence-based analytical methods, including the analysis of highly multiplexed optical reactions in large numbers at high densities, such as single molecule real time nucleic acid sequencing reactions.
Pacific Biosciences Of California, Inc.
02/12/15
20150041406

Method of tracing chemical quantities using encapsulated fluorescent dyes


The invention provides methods and compositions for utilizing encapsulated tracer dyes in difficult liquids such as wastewater or with highly reactive treatment chemicals such as aluminum-based coagulants. In difficult liquids or highly reactive treatment chemicals even so-called “inert” tracers end up reacting and their fluorescence changes.
Ecolab Usa Inc.
12/25/14
20140378344

Carbofluorescein lactone ion indicators and their applications


Fluorescent dyes useful for preparing fluorescent metal ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators for the detection, discrimination and quantification of metal cations are provided.. .
Aat Bioquest, Inc.
12/11/14
20140365159

Fluorescence intensity correcting method, fluorescence intensity calculating method, and fluorescence intensity calculating apparatus


A fluorescence intensity calculating apparatus, includes a measuring section configured to receive fluorescences generated from plural fluorescent dyes excited by radiating a light to a microparticle multiply-labeled with the plural fluorescent dyes having fluorescence wavelength bands overlapping one another by photodetectors which correspond to different received light wavelength bands, respectively, and whose number is larger than the number of fluorescent dyes, and obtain measured spectra by collecting detected values from the photodetectors, and a calculating section configured to approximate the measured spectra based on a linear sum of single-dyeing spectra obtained from the microparticle individually labeled with the fluorescent dyes, thereby calculating intensities of the fluorescences generated from the fluorescent dyes, respectively.. .
12/11/14
20140363091

Tamper detection with microcaspule rupture


Exemplary embodiments of the present invention disclose a method for detecting a tampering event of a component. In a step, an exemplary embodiment encapsulates a fluorescent dye in one or more microcapsules.
12/04/14
20140357869

Novel heterocyclic fluorescent dyes and production thereof


The invention relates to novel compounds of formula (iii) that can be used as heterocyclic dyes of unique structure and properties. These dyes can be obtained in a three-step synthesis from simple substrates..
12/04/14
20140356974

Coatings for measuring ph changes


A ph detectable coating. The ph detectable coating includes a ph insensitive fluorescent dye and a ph sensitive fluorescent dye.
12/04/14
20140356873

Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings


The present invention describes novel dyes, including coumarins, rhodamines, and rhodols that incorporate additional fused aromatic rings. The dyes of the invention absorb at a longer wavelength than structurally similar dyes that do not possess the fused aromatic rings.
12/04/14
20140356293

Fluorescent compositions with enhanced fluorescence and methods based thereon


Fluorescent compositions with enhanced fluorescent intensity are provided. Methods for using the fluorescent compositions in medical imaging are also provided.
11/27/14
20140349297

Fluorescent dyes based on acridine and acridinium derivatives


The present invention relates to fluorescent dyes based on acridine and acridinium derivatives and use of such dyes in for example, biochemical and/or cell-based assays.. .
11/27/14
20140349282

Cell permeable, fluorescent dye


The dye (i) absorbs and emits light at wavelengths above 600 nm; (ii) possesses high photostability; (iii) has high extinction coefficients and high quantum yields; (iv) can be derivatized with different molecules; and (v) is membrane-permeable and shows minimal background binding to biomolecules and biomolecular structures.. .
11/27/14
20140345195

Solar energy funneling using thermoplastics for agricultural applications


Disclosed is a wavelength-conversion material, and methods for its use, that includes an organic fluorescent dye and a polymeric matrix, wherein the organic fluorescent dye is solubilized in the polymeric matrix, and wherein the polymeric matrix is capable of absorbing light comprising a wavelength of 500 to 700 nm and emitting the absorbed light at a wavelength of greater than 550 to 800 nm.. .
11/06/14
20140329228

Fluorescence immunoassay using polypeptide complex containing fluoro-labeled antibody variable region


(c) calculating the amount of the antigen contained in the sample or visualizing the antigen using the positive correlation between the antigen concentration and the fluorescence intensity of the fluorescent dye(s) as an indicator, thereby measuring the concentration of the target antigen existing in the test substance.. .
10/30/14
20140319421

Photosensitive resin composition and color filter using the same


Disclosed are a photosensitive resin composition including a composite dye that includes a red fluorescent dye re-emitting light at a 400 to 800 nm fluorescent wavelength; and a metal complex dye including at least one metal ion selected from mg, ni, co, zn, cr, pt, and pd, and a color filter using the same.. .
10/30/14
20140319378

Optical fluorescence-based chemical and biochemical sensors and methods for fabricating such sensors


An optical fluorescence-based sensor comprising at least one sensing element is disclosed. In one aspect, the at least one sensing element comprises a waveguide comprising a waveguide core, a light source optically coupled to an input part of the waveguide core, and a photodetector optically coupled to an output part of the waveguide core, the waveguide core being made of a material comprising a mixture of an optical material and a fluorescent dye..
10/23/14
20140314670

Clicked somatostatin conjugated analogs for biological applications


The invention relate to the new conjugated somatostatin analogs of formula (i), wherein a- is h or tag-b—, wherein —b— is 0 or a spacer, wherein tag is a chelating agent (e.g. Dota), a fluorescent dye, (e.g.
10/16/14
20140308656

Methods for production and use of substance-loaded erythrocytes (s-ies) for observation and treatment of microvascular hemodynamics


Disclosed herein are methods, kits, and compositions for medical imaging relating to fluorescent dyes entrapped in erythrocytes. Also disclosed therein are methods, and compositions further comprising erythrocytes entrapping at least one therapeutically active agent, as well as methods for releasing the entrapped therapeutically active agent(s).
10/16/14
20140308210

Real time imaging during solid organ transplant


A method of determining the patency of a donor organ or at least one vessel to a donor organ in a donor subject includes administering a fluorescent dye to the donor subject, applying a sufficient amount of energy to the vessel such that the fluorescent dye fluoresces, obtaining a fluorescent image of the donor organ or the vessel attached to a donor organ, and observing the image to determine if a fluorescent signal is continuous through the vessel. A continuous fluorescent signal in the donor organ or vessel indicates the respective donor organ or vessel is patent.
10/09/14
20140303003

Fluorescent dye compounds, conjugates and uses thereof


The present teachings generally relate to fluorescent dyes, linkable forms of fluorescent dyes, energy transfer dyes, reagents labeled with fluorescent dyes and uses thereof.. .
09/18/14
20140273151

Enzyme substrate comprising a functional dye and associated technology and methods


Enzyme substrates and associated technology of the present invention are provided. An enzyme substrate of the invention may comprise a biologically functional fluorescent dye and an enzyme-specific substrate moiety attached in such a way that the functionality of the functional dye is diminished.
09/18/14
20140273060

Reagents, analyzing white blood cells


Aspects of the invention include wbc analysis reagents, systems and methods that can be used for analyzing a sample of whole blood to identify, classify, and/or quantify white blood cells (wbc) and wbc sub-populations in the sample. The wbc analysis reagents of the present disclosure generally include at least one membrane-permeable fluorescent dye, a wbc protecting reagent, and a surfactant.
09/18/14
20140271894

Matrix-incorporated fluorescent porous silica particles for drug delivery


A fluorescent porous silica particle for drug delivery includes a bridged silane fluorescent dye incorporated throughout the particle's matrix. Copolymerization of a bridged silane fluorescent dye (e.g., (r′o)3si—r—si(or′)3, where r is a fluorescent organic bridging group, and where r′ is a methyl or ethyl group) and a tetralkoxysilane (e.g., si(or′)4, where r′ is a methyl or ethyl group) in the presence of a surfactant generates matrix-incorporated fluorescent porous silica particles of a predetermined size and shape.
09/18/14
20140271481

Matrix-incorporated fluorescent porous and non-porous silica particles for medical imaging


A silica particle for medical imaging includes a bridged silane fluorescent dye incorporated throughout the particle matrix. Copolymerization of a bridged silane fluorescent dye (e.g., (r′o)3si—r—si(or′)3, where r is a fluorescent organic bridging group, and where r′ is a methyl or ethyl group) and a tetralkoxysilane (e.g., si(or′)4, where r′ is a methyl or ethyl group) generates particles of a predetermined size and shape.
09/18/14
20140268320

Image processing apparatus, microscope system, image processing method, and computer-readable recording medium


An image processing apparatus includes an image input unit configured to input a plurality of images acquired by imaging a specimen stained with non-fluorescent dye at a plurality of wavelength bands that are different from one another and a characteristic amount calculation unit configured to calculate a characteristic amount representing auto-fluorescence emitted by the specimen based on the plurality of images.. .
09/11/14
20140256073

Simultaneous modulation of quantum dot photoluminescence using orthogonal fluorescence resonance energy transfer (fret) and charge transfer quenching (ctq)


Quantum dots are modified with varying amounts of (a) a redox-active moiety effective to perform charge transfer quenching, and (b) a fluorescent dye effective to perform fluorescence resonance energy transfer (fret), so that the modified quantum dots have a plurality of photophysical properties. The fret and charge transfer pathways operate independently, providing for two channels of control for varying luminescence of quantum dots having the same innate properties..
09/11/14
20140255321

Active sunscreen composition


The invention relates to topical compositions comprising a fluorescent dye that absorbs uva and uvb radiation and converts it into a healing light, in combination with a dermatologically acceptable excipient. The compositions of the invention are useful for repairing photo-damaged skin cells and reducing or preventing future skin damage as a result of exposure to uv light..
08/28/14
20140243429

Enzyme-degradable polymer and application thereof


The present invention belongs to the biomedicine field and specifically concerns an enzyme-degradable polymer and the application thereof. To solve the problem of low sensitivity of the existing assay reagents, the present invention provides an enzyme-degradable polymer and the related application of the polymer.
08/21/14
20140234979

Rapid protein labeling and analysis


The present invention provides methods and compositions for labeling, separating and analyzing proteins, particularly a specific protein of interest within a cell lysate or in a mixture of proteins. The proteins are labeled with an amine reactive or thiol reactive fluorescent dye, or an amine reactive fluorogenic reagent that becomes fluorescent upon reacting to amine groups located on the protein.
08/21/14
20140234855

Chromophore compositions and methods of making and using the same


Chromophore compositions and methods of making and using the same are provided. Aspects of the chromophore compositions include a chromophore component having a chromophore, such as a fluorescent dye moiety, stably associated with a prosthetic group binding cavity of a metalloprotein.
08/21/14
20140234833

Sperm staining and sorting methods


A method of sex sorting sperm is disclosed. The sperm may be stained with a dna selective fluorescent dye, which fluoresces when excited, a dead quenching dye, which selectively quenches fluorescence emitted by the dna selective fluorescent dye within the membrane of compromised sperm, and a split enhancing dye.
08/21/14
20140234226

Plasmonic stable fluorescence superparamagnetic iron oxide nanoparticles and a synthesizing the same


The various embodiments herein provide for the engineered multimodal super paramagnetic iron oxide nanoparticles (spions) with a fluorescent dye. The spions comprise fluorescent polymer dye arranged in a gap between a spion core and a gold shell.
08/07/14
20140220588

Fluorescent dyes with phosphorylated hydroxymethyl groups and their use in light microscopy and imaging techniques


Wherein w=op(o) y1y2 or p(o) y1y2, where y1 and y2 independently denote any of the following residues: oh, o(−), ora and orb, nhra and nhrb, nrarb and nrcrd, ora and nhrb, ora and nrbrc, nhra and nrbrc; and any salt thereof.. .
08/07/14
20140219924

Medical tissue-marker and manufacturing the same


The present invention is to provide a medical tissue-marker which enables the identification of a location even from the outside of an organ, can remain topical over a long period, and enables the easy identification of a marked location within the whole organ; also to provide a manufacturing method for the medical tissue-marker. The medical tissue-marker as in the present invention includes a vesicle formed by the synthesis of a phospholipid and a near infrared fluorescent dye, and an emulsion formed by the synthesis of the phospholipid and an x-ray contrast medium, and has agglomerated clusters wherein the vesicle and the emulsion are contained in a hydrophilic solvent and a plurality of capsules are formed by means of an emulsifier..
07/31/14
20140213898

Method for detecting fluid injection in a patient


A method for detecting fluid injection in a patient, the method including the steps of providing a fluid storage tank; providing fluid for use in machinery and adding said fluid to the fluid storage tank; and providing a fluorescent dye and adding the fluorescent dye to the fluid such that the fluid fluoresces in the presence of ultraviolet light.. .
07/31/14
20140209836

Aqueous dispersions of polymers which comprise a fluorescent dye, process for their production and their use for marking materials


Aqueous dispersions of polymers which are obtainable by free radical suspension polymerization of ethylenically unsaturated monomers in an oil-in-water emulsion whose disperse phase comprises at least one fluorescent dye dissolved in at least one ethylenically unsaturated monomer and has an average particle diameter of at least 1 μm, in the presence of at least one surface-active compound and at least 0.5% per weight, based on the monomers, of at least one hydrophobic, nonpolymerizable organic compound, of a hydrophobic polymer of at least one c2- to c6-olefin having a molar mass mw of up to 10 000, of a siloxane having a molar mass mw of up to 5000 and/or polystyrene having a molar mass mw of up to 10 000, processes for the preparation of these dispersions and use of aqueous dispersions of polymers which are obtainable by free radical suspension polymerization or by free radical miniemulsion polymerization of ethylenically unsaturated monomers in an oil-in-water emulsion whose disperse phase comprises at least one fluorescent dye in at least one ethylenically unsaturated monomer and has an average particle diameter of at least 100 nm, in the presence of at least one surface-active compound and at least 0.5% by weight, based on the monomers, of at least one hydrophobic, nonpolymerizable, organic compound, of a hydrophobic polymer of at least one c2- to c6-olefin having a molar mass mw of up to 10 000, of a siloxane having a molar mass mw of up to 5000 and/or polystyrene having a molar mass mw of up to 10 000 and of the powders obtainable from these polymer dispersions in each case by drying and comprising at least one fluorescent dye for the marking of materials.. .
07/24/14
20140206872

Fluorescent dye


There is provided a fluorescent dye which can improve the fluorescent intensity at the time of labeling to thereby detect a biomolecule with higher sensitivity. The fluorescent dye of the present invention includes a nitrogen cation-containing group or a nitrogen-containing group.
07/24/14
20140206870

Fluorscent dyes with large stokes shifts


Herein are disclosed fluorescent dyes based around a framework for a ligand comprising a pyridyl group linked to a diaryl anilido unit. A variety of ligands based on this framework are disclosed.
07/24/14
20140206580

Protein microarray assay imager


An approach is described that combines distinct properties of a specialized porous nitrocellulose film (pnc) with quantum nanoparticles to create an improved assay and detection sensitivity, permitting the development of a camera-based imaging system for fluorescent detection of macromolecules in microarray format. The two properties of pnc that facilitate the approach are an extraordinarily high binding capacity and a newly observed internal scattering of light.


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Fluorescent Dye topics: Fluorescent Dye, Fluorescent Dyes, Fluorescence, Nucleotide, Fluorescent Label, Polymorphism, Base Sequence, Oligonucleotide, Sensitizer, Solventless, Quantum Dot, Adsorption, Compatibility, Wastewater, Biological Molecule

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