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Factor patents



      
           
This page is updated frequently with new Factor-related patent applications. Subscribe to the Factor RSS feed to automatically get the update: related Factor RSS feeds. RSS updates for this page: Factor RSS RSS


Network infrastructure management

Network infrastructure management

Multi-asset portfolio simulation (maps)

Multi-asset portfolio simulation (maps)

Date/App# patent app List of recent Factor-related patents
10/23/14
20140317591
 Methods and systems for treatment regimen management patent thumbnailMethods and systems for treatment regimen management
Methods and systems for analyzing software development risks are described. In one embodiment, a plurality of risk factor questions associated with a software development process of a software program during a software development stage in which the software program is being created or will be created are generated.
10/23/14
20140317277
 Network infrastructure management patent thumbnailNetwork infrastructure management
In one embodiment, the present invention is a network infrastructure management system that allows monitoring and controlling network devices while dynamically discovering them on demand during the process. New management protocols can be dynamically added to the system or built on demand without refactoring the existing algorithms..
10/23/14
20140317021
 Multi-asset portfolio simulation (maps) patent thumbnailMulti-asset portfolio simulation (maps)
An exemplary system according to the present disclosure comprises a computing device that in operation, causes the system to receive financial product or financial portfolio data, map the financial product to a risk factor, execute a risk factor simulation process involving the risk factor, generate product profit and loss values for the financial product or portfolio profit and loss values for the financial portfolio based on the risk factor simulation process, and determine an initial margin for the financial product. The risk factor simulation process can be a filtered historical simulation process..
10/23/14
20140315984
 Methods and compositions for treatment of diabetes and related disorders patent thumbnailMethods and compositions for treatment of diabetes and related disorders
The present invention provides a method of stimulating growth of a pancreatic islet beta cell and/or enhancing glucose stimulated insulin secretion of a pancreatic islet beta cell, comprising delivering to the cell an exogenous nucleotide sequence encoding nkx6.1 transcription factor.. .
10/23/14
20140315815
 Use of sulfated glycosaminoglycans for improving the bioavailability of factor viii patent thumbnailUse of sulfated glycosaminoglycans for improving the bioavailability of factor viii
The present invention relates to pharmaceutical preparations comprising one or more factor viii and a sulfated glycosaminoglycan for increasing the bioavailability of factor viii upon non-intravenous administration. The invention further relates to the combined use of factor viii and a sulfated glycosaminoglycan for the treatment and prevention of bleeding disorders, whereby the bioavailability of factor viii is increased, and to a method for increasing the bioavailability after non-intravenous administration of factor viii by coadminstration of a sulfated glycosaminoglycan..
10/23/14
20140315805
 Locally released growth factors to mediate motor recovery after stroke patent thumbnailLocally released growth factors to mediate motor recovery after stroke
Methods of improving recovery of a mammal after an ischemic event (e.g., stroke) are provided. In various embodiments the methods involve administering a neural growth factor (e.g., bdnf) into the infarct (e.g., stroke) cavity in a biocompatible hydrogel formulation.
10/23/14
20140315803
 Methods for stimulating hair growth patent thumbnailMethods for stimulating hair growth
A method for promoting hair growth in a human in need of promoting hair growth. The method includes preparing a composition comprising a therapeutically effective amount of at least three of: a bone morphogenetic protein, transforming growth factor beta, platelet derived growth factor, insulin-like growth factor, basic fibroblastic growth factor and vascular endothelial growth factor; and administering the composition to the human..
10/23/14
20140315801
 Methods of treatment of cell proliferative and/or ophthalmic diseases, disorders and conditions using  inhibitors of protein tyrosine kinase activity patent thumbnailMethods of treatment of cell proliferative and/or ophthalmic diseases, disorders and conditions using inhibitors of protein tyrosine kinase activity
This invention relates to methods for treating cell proliferative diseases and conditions and ophthalmic diseases, disorders and conditions using compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to the methods of treatment which utilize compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of vegf receptor signaling..
10/23/14
20140315785
 Methods related to the treatment of neurodegenerative and inflammatory conditions patent thumbnailMethods related to the treatment of neurodegenerative and inflammatory conditions
The invention includes methods of neuroprotection, inducing release of neurotrophic factors, inhibiting the over-activation of innate immune cells, attenuating the toxin-induced death and/or damage of tissues, reducing inflammation, treating an inflammation-related condition, and inhibiting nadph oxidase, that includes contacting or administering an effective amount of at least one compound of the invention that include: valproic acid, sodium butyrate, and salts thereof; opioid peptides; a peptide comprising the tripeptide ggf; and morphinans, such as naloxone, naltrexone, 3-hydroxy-morphinan and dextromethorphan.. .
10/23/14
20140315752
 Methods and compositions for diagnosis and prognosis of renal injury and renal failure patent thumbnailMethods and compositions for diagnosis and prognosis of renal injury and renal failure
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of stanniocalcin-1, antithrombin-iii, toll-like receptor 2, triiodothyronine (t3), thyroxine (t4), extracellular matrix protein 1, coagulation factor xiii a chain, coagulation factor xiii b chain, interleukin-17f, interleukin-22, vitronectin, progesterone, estradiol, growth/differentiation factor 15, and proprotein convertase subtilisin/kexin type 9 as diagnostic and prognostic biomarkers in renal injuries..
10/23/14
20140315307
Mixed population of cells deriving from adipose tissue and methods of isolating and using the same
Adipose tissue-derived stromal cells and methods of isolating and using the same. In at least one embodiment of isolated adipose tissue-derived stromal cells of the present disclosure, the cells are isolated by performing adipose tissue resection or suction on a mammalian patient, dissecting tissue obtained from said tissue resection or suction and dissociating said tissue into a cell suspension, removing adipocytes from the cell suspension, culturing the adipocyte-depleted cell suspension in egm-2-mv media, and isolating adipose tissue-derived stromal cells secreting vascular endothelial growth factor (vegf), hepatocyte growth factor (hgf), and granulocyte-colony stimulating factor (g-csf)..
10/23/14
20140315306
Cell culture substrate comprising a laminin and a cadherin
The present disclosure related to isolated laminin-521, methods for making recombinant laminin-521, host cells that express recombinant laminin-521, and compositions containing laminin-521. Laminin-521 can maintain stem cells in vitro pluripotency, enable self-renewal, and enable single cell survival of human embryonic stem cells.
10/23/14
20140315224
Detection device, detection strip, and detection system
A detection device applied for detecting body fluids includes a substrate and a plurality of anti-growth factor antibodies. The substrate includes at least one reaction portion.
10/23/14
20140314726
Fibroblasts for treatment of degenerative disc disease
The present invention concerns methods and compositions for differentiating cells, including human fibroblasts, into chondrocyte-like cells via in vivo mechanical strain. In particular aspects, fibroblasts are delivered to a joint, such as an intervertebral disc, following which the fibroblasts differentiate into chondrocyte-like cells to treat dysfunction of cartilage therein, including to repair degenerated discs, for example.
10/23/14
20140314667
Methods of treating epidermal growth factor deletion mutant viii related disorders
The present invention relates to methods of treating treating epidermal growth factor deletion mutant viii (egfrviii) related disorders, such as glioblastoma or anaplastic astrocyte tumors, using antigen binding proteins, including antibodies against egfrviii conjugated to a drug. Diagnostic and therapeutic formulations of such antibodies and drug conjugates thereof are also provided..
10/23/14
20140313775
Led light fixture and assembly method therefor
An led panel light fixture and method for assembling the same includes (a) selecting a set of specifications of the led panel light fixture, the set of specifications comprising a fixture/base specification comprising a form factor of the led panel light fixture; and a top specification comprising a visual feature of a top in accordance with the top specification; (b) providing a knock-down kit having parts including the top in accordance with the top specification, a frame in accordance with the fixture/base specification, an optically transmissive panel assembly, a set of light emitting diodes (leds), and driving circuitry; and (c) assembling the led panel light fixture using parts of the knock-down kit. An led panel lighting fixture kit includes a top and a base.
10/23/14
20140313551
Cover for handheld portable electronic device
A method displays a template, an hped, and an image selector. The template is marked with zones to display selected images, and the hped includes a cover that has surfaces to display the selected images.
10/23/14
20140312827
Modular system having expandable form factor
A modular system of devices, in which a (master) device can be combined with one or more of other (slave) devices to transform to functional electronic devices having expanded functionalities and features in different form factors and/or platforms. The master device is docked to the slave device via a data/electrical interface, to transform the master device to the larger form factor of the slave device, with the master device maintaining control of the slave device, substantially based on the operating system installed in the master device, with access to the data, application programs, functionalities and features embodied in the master device.
10/23/14
20140312558
Double-sided image recording device having a compact form factor
An image recording device is provided, having a recording unit configured to record an image on a sheet, and a tray disposed below the recording unit. The tray includes a sheet holding surface configured to hold the sheet.
10/23/14
20140312554
Double-sided image recording device having a compact form factor
An image recording device is provided, having a recording unit configured to record an image on a sheet, and a tray disposed below the recording unit. The tray includes a sheet holding surface configured to hold the sheet.
10/23/14
20140311907
Systems and methods for assay of bio-contaminants in water
A method of determining water quality of a water sample, comprising exposing the water sample to a test cell system; generating at least one profile of ensuing changes in activities of transcription factors in said test cell system in response to said exposing; and determining from the generated at least one profile the water quality of the water sample. Computer systems and kits for carrying out the water quality determination of water specimens are also described, in which water quality can be readily and accurately determined by transcription factor activity analysis..
10/16/14
20140310832
Stress tolerant wheat plants
The present invention relates to stress tolerant transgenic wheat plants. In particular, the present invention relates to stress tolerant transgenic wheat plants comprising an exogenous polynucleotide encoding a nac transcription factor operably linked to a promoter capable of directing expression of the polynucleotide in a cell of the plant..
10/16/14
20140310643
Mobile device with user interface
There is provided a bar form factor mobile display device comprising front and back major faces, the front major face arranged to present a normal power first display screen and the back major face arranged to present a low power second display screen, wherein the device includes a computer.. .
10/16/14
20140309746
Medical implants and methods for delivering biologically active agents
Medical implants, such as orthopedic implants of the type used in partial or total joint replacement procedures, for example. The implants include a porous substrate, and a bearing portion of a polymeric material, for example, which is at least partially molded within the porous substrate.
10/16/14
20140309436
Thalidomide analogs
Thalidomide analogs that modulate tumor necrosis factor alpha (tnfα) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs.
10/16/14
20140309177
Compositions and methods for the induction and tuning of gene expression
Disclosed herein are compositions of transcription activator-like effectors transcription factors and methods of using said compositions for inducing gene expression of mammalian genes.. .
10/16/14
20140309159
Compositions and methods for targeting nuclear import shuttles and treating inflammatory disorders
The present invention relates to compositions and methods for treating autoimmune, microbial, metabolic, neoplastic, and posttraumatic diseases mediated by inflammation in a subject. Compositions and methods including at least one importin beta-selective nuclear transport modifier (ntm) and/or at least one importin alpha-selective ntm, and/or at least one importin alpha-specific ntm, and/or at least one inhibitor of importin alpha and importin beta complex formation may be administered to a subject to modulate the transport of transcription factors, mediated by nuclear import adaptors, into the nucleus of a cell resulting in a decrease or abrogation of inflammation..
10/16/14
20140308747
Ex vivo expansion of human hematopoietic stem cells
Methods and kits for expanding the number of hematopoietic stem cells are provided. The methods comprise incubating cells in medium comprising isolated igfbp-2 and an angiopoietin-like protein (angptl).
10/16/14
20140308743
Method for culturing stem cell
The present invention provides a method of obtaining aggregates containing a rostral hypothalamus tissue and a rostral head ectodermal tissue, a hypophysis precursor tissue and a hypophysis hormone producing cell, by using a serum-free medium (preferably substantially free of growth factor and insulins), forming homogeneous aggregates of stem cells from pluripotent stem cells such as es cell and the like, which are plated at a high cell concentration, and subjecting the formed aggregates to floating-culture.. .
10/16/14
20140308707
Method for production of factor viii
The present invention relates to methods of producing a factor viii polypeptide in mammalian cell cultures.. .
10/16/14
20140308703
Mammalian cell lines for increasing longevity and protein yield from a cell culture
Disclosed are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hormones, and vaccines. Cells transfected with an apoptosis-inhibiting gene or vector, such as a triple mutant bcl-2 gene, can survive longer in culture, resulting in extension of the state and yield of protein biosynthesis.
10/16/14
20140308288
Antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof
An antibody of the invention interacts with human dr5 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Nucleic acid sequences and amino acid sequences of anti-dr5 antibodies have been elucidated and vectors and cells containing and expressing these sequences have been generated.
10/16/14
20140308280
Factor viii polypeptide formulations
The present invention provides a formulation of a factor viii polypeptide, e.g., fviii-fc, and methods of using the same. The fviii polypeptide can be a recombinant fviii protein, a short-acting fviii protein, or a long-acting fviii protein.
10/16/14
20140308256
Methods for use of neural stem cell compositions for treatment of central nervous system lesions
Methods for inducing non-embryonic lesioned central nervous system neurons to survive, integrate, extend axons over long distances, induce intra-lesion ingrowth of neurons into the lesion from host tissue and form synapses in vivo. Pluripotent neural stem cells are grafted into the lesioned cns tissue within a tissue adhesive suspension, optionally in the presence of growth factors.
10/16/14
20140308254
Methods and compositions for treating diabetes and other degenerative neuroendocrine diseases or disorders
The present application describes the use of adult human olfactory neuroepithelium (one) stem cells in the treatment of diabetes.. .
10/16/14
20140304915
Occupant support adapted to manage pressure ulcer risk and associated risk management methods
A method of accommodating pressure ulcer vulnerability of an occupant of an occupant support, a method of managing pressure ulcer risk of an occupant of an occupant support, and an occupant support adapted to manage pressure ulcer risk of an occupant thereof are disclosed. The methods and occupant support account for occupant specific or occupant class specific risk factors based on empirical data..
10/09/14
20140304857
Maize stress related transcription factor 18 and uses thereof
A truncated stress-responsive transcription factor can be overexpressed without causing unfavorable pleiotropic effects. The truncation may result in deletion of a nuclear localization signal.
10/09/14
20140303993
Systems and methods for identifying fraud in transactions committed by a cohort of fraudsters
Disclosed are systems and methods for identifying potential fraud committed by a cohort of people using models for identifying relationships among people to build the cohort and using fraud models to identify indicators of frauds from attributes of people. Embodiments may predict a likelihood applicants seeking privileges to distribute governmental benefits by identifying members of a cohort associated with an applicant, assigning a value to the strengths of the relationships between people in the cohort, determining weights for identified indicators of fraud identified using fraud models, determining a risk score for the cohort using the values and data points, and then performing a clustering analysis for the risk score of the cohort to determine a risk factor for fraud committed by the applicant and the cohort..
10/09/14
20140303367
Methods for synthesizing molybdopterin precursor z derivatives
The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates of the formula (i) and formula (xiii) compounds. These compounds are useful for treating diseases associated with molybdenum cofactor deficiency..
10/09/14
20140303352
Genes that increase plant oil and method for using the same
This invention is intended to be used to search for a transcription factor having novel functions of increasing the weight of an individual plant, increasing the weight of a given tissue per individual plant, or improving the productivity of a given substance per individual plant and to improve such properties in the plant. The weight of an individual plant is increased, the weight of a given tissue per individual plant is increased, the productivity of a given substance per individual plant is improved, or the content of a given substance per given tissue of a plant is increased via expression of a transcription factor that has been modified to suppress transcription accelerating activity..
10/09/14
20140303351
Genes that increase plant oil and method for using the same
This invention is intended to be used to search for a transcription factor having novel functions of increasing the weight of an individual plant, increasing the weight of a given tissue per individual plant, or improving the productivity of a given substance per individual plant and to improve such properties in the plant. The weight of an individual plant is increased, the weight of a given tissue per individual plant is increased, the productivity of a given substance per individual plant is improved, or the content of a given substance per given tissue of a plant is increased via expression of a transcription factor that has been modified to suppress transcription accelerating activity..
10/09/14
20140303350
Genes that increase plant oil and method for using the same
This invention is intended to be used to search for a transcription factor having novel functions of increasing the weight of an individual plant, increasing the weight of a given tissue per individual plant, or improving the productivity of a given substance per individual plant and to improve such properties in the plant. The weight of an individual plant is increased, the weight of a given tissue per individual plant is increased, the productivity of a given substance per individual plant is improved, or the content of a given substance per given tissue of a plant is increased via expression of a transcription factor that has been modified to suppress transcription accelerating activity..
10/09/14
20140303349
Genes that increase plant oil and method for using the same
This invention is intended to be used to search for a transcription factor having novel functions of increasing the weight of an individual plant, increasing the weight of a given tissue per individual plant, or improving the productivity of a given substance per individual plant and to improve such properties in the plant. The weight of an individual plant is increased, the weight of a given tissue per individual plant is increased, the productivity of a given substance per individual plant is improved, or the content of a given substance per given tissue of a plant is increased via expression of a transcription factor that has been modified to suppress transcription accelerating activity..
10/09/14
20140303087
Tsp-1, tsp-2, il-17br and hb-egf associated with stem cell activity and use thereof
Thrombospondin 1 (tsp-1), tsp-2, interleukin 17b receptor (il-17br) and heparin-binding epidermal growth factor-like growth factor (hb-egf) associated with stem cell activity and use thereof.. .
10/09/14
20140302171
Cysteine peptide-containing health drink
An object is to provide a health drink which gives a real feeling of a preventive effect and ameliorative effect against skin aging and stress, and it is confirmed that when a drink in which glutathione is added to a conventional drink containing chondroitin, hyaluronic acid, and vitamins is taken, a concentration of blood dhea-s, which is considered to be an indicator of rejuvenation, is significantly elevated, promoting gene expressions of olfactory receptors and the like, and remarkably ameliorating skin condition, total mood disturbance, autonomic nerve balance, and overall health condition.. .
10/09/14
20140302005
Chimeric factor vii molecules
The present invention relates to chimeric factor vii polypeptides and methods of using the same.. .
10/09/14
20140301943
Induction of thyroid iodide-handling gene expression in human cancers
Dual suppression of the map kinase and pi3k/akt pathways showed synergistic or greatly enhanced anti-melanoma cell effects, compared to suppression of a single pathway, including the inhibition of cell proliferation, transformation and invasion, induction of g0/g1 cell cycle arrest and, importantly, cell apoptosis. Remarkably, suppression of either pathway induces the expression of thyroid iodide-handling genes and dual suppression of the two pathways synergistically and robustly induces expression of these genes, accompanied by uptake of radioiodine in the cells.
10/09/14
20140301563
Wireless earplug with improved sensitivity and form factor
An improved wireless communications earplug for use with a magnetic field transmitter. The wireless earplug has a receiver made of a coil of wire on a magnetic bobbin, mounted in close proximity or in contact with a magnetic case of a speaker.
10/09/14
20140301493
Method and apparatus for adaptive antenna sharing
A method and apparatus are disclosed for sharing antennas between modems for two or more different radio access technologies when two or more antennas may be present in a system. A method for coordination between the modem and the corresponding network element as well as the coordination between the two or more radio access technologies is provided.
10/09/14
20140300498
Method and apparatus pertaining to a touch typing-friendly grid-patterned keyboard
A keyboard can be comprised of a plurality of alphabetic keys that are disposed in an evenly-spaced grid pattern with respect to one another. In any event, these keys have keycaps configured to comport with touch typing as with a keyboard having a plurality of alphabetic keys that are disposed in an offset pattern (such as the classic qwerty offset-pattern typewriter-styled keyboard).
10/02/14
20140298540
Genes that increase plant oil and method for using the same
This invention is intended to be used to search for a transcription factor having novel functions of increasing the weight of an individual plant, increasing the weight of a given tissue per individual plant, or improving the productivity of a given substance per individual plant and to improve such properties in the plant. The weight of an individual plant is increased, the weight of a given tissue per individual plant is increased, the productivity of a given substance per individual plant is improved, or the content of a given substance per given tissue of a plant is increased via expression of a transcription factor that has been modified to suppress transcription accelerating activity..
10/02/14
20140298535
Nucleic acid sequences encoding transcription factors regulating alkaloid biosynthesis and their use in modifying plant metabolism
Plant metabolism and alkaloid levels can be regulated by transcription factors that regulate the nicotinic alkaloid biosynthetic pathway. In one embodiment, the disclosure provides a transcription factor that negatively regulates alkaloid biosynthesis, such as nicotine biosynthesis..
10/02/14
20140297562
System and method for enabling transfer of systemic risk exposure
A system and computer-implemented method of facilitating transfer of systemic risk exposure between a plurality of entities having asset portfolios with a sensitivity to one or more of a plurality of common risk factors, the method comprising: for each entity, receiving data representative of the risk appetite of that entity to provide or receive in relation to a counterparty an amount of protection against a given loss in connection with one or more of the said risk factors; and using said data representative of the risk appetites of said entities, matching counterparties to trade systemic risk exposure by way of one or more derivatives contracts for a relevant amount of said protection against a given loss in connection with one or more of the said risk factors.. .
10/02/14
20140297395
End-to-end effective citizen engagement via advanced analytics and sensor-based personal assistant capability (eeceaspa)
Providing an end-to-end citizen engagement, in one aspect, may comprise obtaining data of multiple disintegrated sources from one or more of communication and social computing channels via one or more adapters. Data refactoring and management, integration and process orchestration of the data according to a data model as data attributes of the data model may be provided.
10/02/14
20140296326
Epidermal growth factor receptor (egfr) and methods of use in adenoviral-associated virus type 6 (aav6) transduction
Comparative gene analysis (cga) was combined with pathway visualization software to identify a positive correlation between aav6 transduction and epidermal growth factor receptor (egfr) expression. It was found that egfr is necessary for vector internalization and functions as a co-receptor for aav6.
10/02/14
20140296223
Method for regulating skin pigmentation
This invention relates to a method for regulating skin pigmentation of a subject, comprising the step of administering the agent for inhibiting the expression or activation of microphthalmia transcription factor (mitf) to the subject who is in need of regulation of skin pigmentation.. .
10/02/14
20140296216
Pyrimido[4,5-d]pyrimidinyl compounds, pharmaceutical compositions and uses thereof
A compound of formula (i) or (ii) and use of the compound in the preparation of drugs for treating cancer are disclosed. The study shows that the compounds can inhibit the growth of many kinds of tumor cells, can be used for targeting epidermal growth factor receptor (egfr), and particularly can inhibit tumor cells with single or multiple mutations of egfr (t790m).
10/02/14
20140296214
Substituted tetrahydroisoquinoline compounds as factor xia inhibitors
The present invention provides compounds of formula (i): or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor xia and/or plasma kallikrein which may be used as medicaments..
10/02/14
20140296129
Regulation of receptor expression through delivery of artificial transcription factors
The invention relates to an artificial transcription factor comprising a polydactyl zinc finger protein targeting specifically a receptor gene promoter fused to an inhibitory or activatory protein domain, a nuclear localization sequence, and a protein transduction domain. In particular examples these receptor gene promoters regulate the expression of the endothelin receptor a, the endothelin receptor b, the toll-like receptor 4 or the high-affinity ige receptor.


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