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Factor-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Communication control device, communication control method, and non-transitory computer-readable storage medium
Fujitsu Limited
August 17, 2017 - N°20170238295

A communication control device including a memory and a processor coupled to the memory and the processor configured to select a radio access technology among from a first radio access technology and second radio access technology based on utilization efficiency, a first load factor and a second load factor, the utilization efficiency depending on a packet length of a packet ...
Computer-implemented methods and systems for measuring, estimating, and managing economic outcomes and technical debt in ...
Silverthread, Inc.
August 17, 2017 - N°20170235569

An interrelated set of tools and methods is disclosed for: (1) measuring the relationship between software source code attributes (such as code quality, design quality, test quality, and complexity metrics) and software economics outcome metrics (such as maintainability, agility, and cost) experienced by development and maintenance organizations, (2) using this information to project or estimate the level of technical debt in a ...
Target selection on a small form factor display
Google Inc.
August 17, 2017 - N°20170235439

A method may include identifying, from a set of applications, a subset of the set of applications, each application from the subset of the set of applications being predicted, by a computing device, to be selected by a user. The method may also include outputting a graphical user interface that includes: a plurality of application icons representing the set of ...
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Human factor xiii as a normalization control for immunoassays
Bio-rad Laboratories, Inc.
August 17, 2017 - N°20170234877

The present disclosure provides compositions and methods that are useful for normalizing the amount of signal detected in an assay, such as an immunoassay. The compositions and methods are useful for improving the accuracy of immunoassays, such as immunoassays that detect whether a subject is infected with a retrovirus such as hiv.
Retrofit device and method of retrofitting a flow meter
Olea Networks, Inc.
August 17, 2017 - N°20170234709

A retrofit device and method of installing such a device for supplementing a legacy flow meter in a fluid pipe system. The retrofit device enhances the function of the legacy flow meter by providing a digital interface and means for error diagnostics and tamper detection. The retrofit device adapts to the mechanical and casing form factor design of the legacy ...
Antidotes for factor xa inhibitors and methods of using the same
Portola Pharmaceuticals, Inc.
August 17, 2017 - N°20170233711

The present invention relates antidotes to anticoagulants targeting factor xa. The antidotes are factor x and factor xa protein derivatives that bind to the factor xa inhibitors thereby substantially neutralizing them but do not assemble into the prothrombinase complex. The derivatives describe herein lack or have reduced intrinsic coagulant activity. Disclosed herein are methods of reversing anticoagulation, stopping or preventing ...
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Cell culture media composition and methods of producing thereof
Neuclone Biologics Pty Ltd
August 17, 2017 - N°20170233695

A serum free cell culture media, wherein the media is adapted to be conditioned by culturing a first set of eukaryotic cells in the media, wherein the first set of eukaryotic cells use an expression vector to excrete levels of desired complex proteins into the media; wherein said desired complex proteins include human growth hormone (hgh), growth hormone-like growth factors, ...
Anti-vegfr antibody and uses thereof
Development Center For Biotechnology
August 17, 2017 - N°20170233480

The present invention relates to an antibody or antigen-binding fragment thereof that bind human vascular endothelial growth factor receptor 2 (vegfr-2). The present invention also relates to a method for inhibiting vegfr-2-mediated signaling in a subject in need, a method for treating diseases and/or disorders caused by or related to vegfr-2 activity and/or signaling in a subject afflicted ...
An improved expression cassette for packaging and expression of variant factor viii for the treatment ...
The Children's Hospital Of Philadelphia
August 17, 2017 - N°20170233456

Factor viii variants and methods of use thereof are disclosed. In particular embodiments, factor viii variants are expressed more efficiently by cells over wild-type factor viii proteins, are secreted at increased levels by cells over wild-type factor viii proteins, exhibit enhanced activity over wild-type factor viii proteins and are packaged more efficiently into viral vectors.
Viral vectors encoding recombinant fviii variants with increased expression for gene therapy of hemophilia a
Baxalta Gmbh
August 17, 2017 - N°20170233455

The present disclosure provides, among other aspects, codon-altered polynucleotides encoding factor viii variants for expression in mammalian cells. In some embodiments, the disclosure also provides mammalian gene therapy vectors and methods for treating hemophilia a.
Low cost wafer level process for packaging mems three dimensional devices
The Regents Of The University Of California
August 17, 2017 - N°20170233247

An apparatus and method for wafer-level hermetic packaging of microelectromechanical systems (mems) devices of different shapes and form factors is presented in this disclosure. The method is based on bonding a glass cap wafer with fabricated micro-glassblown “bubble-shaped” structures to the substrate glass/si wafer. Metal traces fabricated on the substrate wafer serve to transfer signals ...
A method for controlling a drivetrain of a vehicle comprising a multi-clutch transmission
Volvo Truck Corporation
August 17, 2017 - N°20170232971

A method is provided for controlling a drivetrain of a vehicle, wherein the drivetrain comprises a multi-clutch transmission. The gear shift of the multi-clutch transmission is adapted to be performed either by power cut shift or by power shift dependent on predetermined vehicle shift conditions. The method includes detecting at least one of a plurality of indications of slippery road ...
Enhancement of skeletal muscle stem cell engraftment by dual delivery of vegf and igf-1
Brown University
August 17, 2017 - N°20170232074

An improved device and method for extended repair and regeneration of muscle tissue. An exemplary device comprises (a) a scaffold comprising an ecm component; (b) a combination of growth factors such as vegf and igf; and (c) a population of myogenic cells. Implantation of the device leads to muscle regeneration and repair over an extended period of time.
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Promoting epithelial regeneration using heparin binding epidermal growth factor like growth factor
The Board Of Trustees Of The Leland Stanford Junior University
August 17, 2017 - N°20170232065

Compositions and methods for promoting epithelial tissue regeneration to treat an oral or oropharyngeal wound, e. G., after tonsillectomy are disclosed. In particular, the invention relates to compositions comprising heparin binding epidermal growth factor like growth factor and their use in the treatment of an oral or oropharyngeal wound, e. G., post-therapy treatment to promote epithelial tissue regeneration in wounds, ...
Pharmaceutical compositions of edoxaban
Sandoz Ag
August 17, 2017 - N°20170231969

Edoxaban is factor x inhibitor useful for the treatment or the prevention of thrombosis or embolism. A pharmaceutical composition comprising edoxaban, or a pharmaceutically acceptable salt thereof, a water soluble vinylpyrrolidone polymer selected from the group consisting of povidone and copovidone, and a cellulose ether, and not comprising a sugar alcohol, having good dissolution and bioavailability is provided. A process ...
Context-aware delegation risk system
Dell Software, Inc.
August 10, 2017 - N°20170228558

A risk analysis system of associated with an enterprise system for determining delegation risks associated with assigning candidate individuals to perform various tasks. In some cases, the delegation risk analysis system may generate individual delegation risk scores to each candidate individual to assist in the delegation of tasks throughout an organization. In some examples, the delegation risk analysis system may ...
Biomarkers for risk prediction of mortality
Roche Diagnostics Operations, Inc.
August 10, 2017 - N°20170227552

The present invention relates to a method for predicting the risk of a subject of rapidly progressing to chronic heart failure and/or of hospitalization due to chronic heart failure and/or death. The method is based on the determination of at least one biomarker selected from the group consisting of a bnp-type peptide, igfbp7 (igf binding protein 7), a cardiac ...
Methods and vectors to produce vector free induced pluripotent stem cells
Lonza Walkersville, Inc.
August 10, 2017 - N°20170226483

The invention relates generally to methods of generating induced pluripotent stem cells (ipscs) that do not contain the reprogramming vector. In some embodiments, the invention relates to inducing pluripotency in somatic cells by introducing an episomal vector(s) comprising at least one expression cassette containing reprogramming factors and/or synthetic transcription factors and a suicide gene. In some embodiments, the ...
Anti-coagulation factor xi antibodies
Merck Sharp & Dohme Corp.
August 10, 2017 - N°20170226225

Antibodies that bind the apple 2 domain of human coagulation factor xi and inhibit activation of fxi by coagulation factor xiia are described.
Anti-vegfr2 antibody therapy for hepatocellular carcinoma
Imclone, Llc
August 10, 2017 - N°20170226212

The invention provides for a human antibody that binds to human vascular endothelial growth factor receptor 2, preferably ramucirumab, for the treatment of hepatocellular carcinoma in patients having levels of alpha-fetoprotein (afp) of 1. 5 uln or greater, and as a predictive method for the treatment of hcc in patients having afp levels of 1. 5×uln or greater.
Viral vectors encoding recombinant fviii variants with increased expression for gene therapy of hemophilia a
Baxalta Gmbh
August 10, 2017 - N°20170226188

The present disclosure provides, among other aspects, codon-altered polynucleotides encoding factor viii variants for expression in mammalian cells. In some embodiments, the disclosure also provides mammalian gene therapy vectors and methods for treating hemophilia a.
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