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Factor patents



      
           
This page is updated frequently with new Factor-related patent applications. Subscribe to the Factor RSS feed to automatically get the update: related Factor RSS feeds. RSS updates for this page: Factor RSS RSS


Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Method for purifying transgenic factor vii

Date/App# patent app List of recent Factor-related patents
06/25/15
20150178461
 Group posture health risk management patent thumbnailnew patent Group posture health risk management
The seated posture of a subject person and a group of subject persons over a long term is analyzed to determine long-term health risk factors. Responses to the determined long-term health risk factors include posture improvement messages and group activity recommendations to reduce the long-term health risk factors as well as adjustments to reserves and premiums insuring costs associated with the long-term risks..
International Business Machines Corporation
06/25/15
20150177252
 Circulating tumor cell assay patent thumbnailnew patent Circulating tumor cell assay
Methods for the detection, enumeration and analysis of circulating tumor cells expressing insulin-like growth factor-1 receptors (igf-1r) are disclosed. These methods are useful for cancer screening and staging, development of treatment regimens, and for monitoring for treatment responses, cancer recurrence or the like.
Pfizer Inc.
06/25/15
20150177238
 Process for the manufacturing of glycochips patent thumbnailnew patent Process for the manufacturing of glycochips
The present invention relates to a process for the manufacturing of solid supports functionalized by saccharide type molecules (glycochips or carbohydrate arrays or alternatively oligosaccharide arrays). The present invention also relates to the glycochips directly obtained by such a manufacturing process and to their use, in particular for biological analysis and especially for the screening of saccharides or proteins such as hepatocyte growth factors (hgfs) or for the study of saccharides/proteins interactions..
Azbil Corporation
06/25/15
20150176402
 Applications based on fluid properties measured downhole patent thumbnailnew patent Applications based on fluid properties measured downhole
Downhole drilling fluid measurements are made as a function of time or as a function of depth. A change in the downhole drilling fluid measurements is correlated to a feature of a formation penetrated by a drill bit or to a feature of fluids in the formation.
Schlumberger Technology Corporation
06/25/15
20150176081
 Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments patent thumbnailnew patent Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments
Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (egfr) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug..
Dana-farber Cancer Institute, Inc.
06/25/15
20150176039
 Expression construct for sensing cell density and substrate availability and its use in conversion of hydroxycinnamic acids patent thumbnailnew patent Expression construct for sensing cell density and substrate availability and its use in conversion of hydroxycinnamic acids
An expression system; isolated nucleic acid molecule or host cell comprising: (i) a first gene encoding for a first enzyme linked to a first promoter, wherein the first promoter is a time delay promoter; (ii) a second gene encoding for a second enzyme capable of using the product generated by the first enzyme as a substrate, wherein the second gene is operably linked to a second promoter, wherein the second promoter is inducible by the product generated by the first enzyme; (iii) optionally, a third gene encoding a transcription factor that represses expression of the second gene in the absence of the product generated by the first enzyme, wherein the third gene is operably linked to a third promoter that regulates expression of the third gene; and its use in producing a product such as hydroxybenzaldehyde.. .
Nanyang Technological University
06/25/15
20150175985
 Enhancing vegetative protein production in transgenic plants using seed specific promoters patent thumbnailnew patent Enhancing vegetative protein production in transgenic plants using seed specific promoters
In various embodiments, the invention provides expression systems for heterologous protein expression in vegetative plant tissues, utilizing plant seed gene components that are adapted to orchestrate high levels of vegetative protein production. The expression systems may include host plant cells having recombinant genomes, and the plant cells may be maintained under protein expressing conditions, for example in tissue culture.
Simon Fraser University
06/25/15
20150175983
 Method for purifying transgenic factor vii patent thumbnailnew patent Method for purifying transgenic factor vii
An anti-factor vii affinity ligand that is particularly useful for purifying recombinant human activated factor vii from transgenic sources. The affinity ligand combined with other orthogonal chromatographic steps allows the preparation of a highly purified fvii solution fully activated free of aggregates with a low percentage of degraded or oxidized fvii forms..
Laboratoire Francais Du Fractionnement Et Des Biotechnologies
06/25/15
20150175961
 System and method to facilitate the growth of stem cells patent thumbnailnew patent System and method to facilitate the growth of stem cells
A method and system to maintain adult or embryonic stem cells employing 3-d culture conditions is disclosed. Hydrogel scaffolds, composed of hydrophilic polymer networks are provided to emulate a fully hydrated native extracellular matrix and natural soft tissue.
Oakland University
06/25/15
20150175708
 Multifunctional antibodies binding to egfr and met patent thumbnailnew patent Multifunctional antibodies binding to egfr and met
Provided are multifunctional antibodies, and/or antigen-binding fragments, that bind to, and inhibit the activity of, both human epidermal growth factor receptor (egfr) and met, and that are effective in treating cancers and other diseases, disorders, or conditions where pathogenesis is mediated by egfr and met.. .
Eli Lilly And Company
06/25/15
20150175691
new patent

Methods of administering anti-tnfalpha antibodies


Methods of treating disorders in which tnfα activity is detrimental via biweekly, subcutaneous administration of human antibodies, preferably recombinant human antibodies, that specifically bind to human tumor necrosis factor α (htnfα) are disclosed. The antibody may be administered with or without methotrexate.
Abbvie Biotechnology Ltd.
06/25/15
20150174295
new patent

Porous orthopedic materials coated with demineralized bone matrix


A biomaterial including a porous biocompatible structure having interconnected pores, wherein the pores have interior walls and are interconnected by passageways, the interior walls and passageways being coated with an osteoinductive aqueous demineralized bone extract solution, the aqueous demineralized bone extract solution including growth factors, proteins, a demineralized bone matrix and at least one of a weak acid and a guanidine hydrochloride, wherein the demineralized bone matrix is present per 100 g of the solution in an amount of from about 2 g to about 10 g.. .
Biomet Manufacturing, Llc
06/25/15
20150174293
new patent

Biologic treatment system and method


A delivery system is provided that is adapted to treat various urological pelvic disorders, such as prolapse, incontinence, and the like. The delivery system can include at least one biologic loaded or otherwise provided with a bioactive agent, the biologic can comprise any drugs, hormones or steroids, stem cells, growth factors, proteins, and/or other bioactive agents to promote cell or tissue growth for the treatment and strengthening of organ walls or tissue.
Ams Research Corporation
06/25/15
20150174221
new patent

Systems, compositions, and methods for transplantation


Systems and methods for purification and concentration of autologous alpha-2-macroglobulin (a2m) from whole blood are provided. Also provided are diagnostic methods for identifying sites in the synovial joints, spine, tendons or ligaments for treatment of pain, degeneration, or inflammation with autologous a2m.
Cytonics Corporation
06/25/15
20150174215
new patent

One component fibrin glue comprising zymogens


Provided herein is a single component sealant formulation (e.g. In a liquid form), methods for its preparation, and use.
Ethicon, Inc.
06/25/15
20150174149
new patent

Compositions including triciribine and methods of use thereof


This invention encompasses combination therapies including tcn, tcn-p, tcn-pm and/or related compounds and one or more additional anti-cancer agents, for example, taxanes a molecule that modulates the her2/neu (erbb2) receptor, anthracyclin compounds, epidermal growth factor receptor inhibitor compounds, one or more platinum compounds and bortezomib and derivatives thereof and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.. .
University Of South Florida
06/25/15
20150174104
new patent

Systems and methods to treat pain locally


Disclosed herein are systems and methods for contributing to the local treatment of pain. More specifically, the disclosed systems and methods contribute to the local treatment pain by inhibiting the nfκb family of transcription factors..
Warsaw Orthopedic Inc.
06/25/15
20150173537
new patent

Condiment container


A condiment container whose form factor is selected to enable the condiment container to be carried and held in place by a standard drink holder. By configuring the condiment container to be received in a standard drink holder, the problems associated with incorporating a condiment container in a drink container lid are overcome..
06/18/15
20150169715

Refactoring of databases to include soft type information


Method and system are provided for refactoring of databases to include soft type information. The method may include: carrying out data profiling of soft type data to generate an attribute list with mapping suggestions to a hardened database structure; generating a data model definition and extract, transform, and load logic for transforming the soft type data based on the attribute list and mapping suggestions; executing the data model definition to create a new or modified database structure; moving data from an existing database structure to the new or modified database structure; and regenerating a services interface for access to the data..
International Business Machines Corporation
06/18/15
20150169685

System and dynamic collaboration during query processing


A system and method of dynamic collaboration during query processing includes determining a load factor for a data source, receiving a query at a query assistant running on a computer server, determining a complexity of the query, adjusting the complexity by the load factor, simplifying the query by removing one or more first query elements from the query when the adjusted complexity is above a threshold, forming a query plan where the first query elements are designated for processing outside the data source, and performing the query plan by sending one or more abbreviated queries to the data source and processing the first query elements using the query assistant. The abbreviated queries are based on the query with the first query elements removed.
Red Hat, Inc.
06/18/15
20150168422

Methods and compositions for diagnosis and prognosis of renal injury and renal failure


The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of transforming growth factor beta-1, transforming growth factor beta-2, transforming growth factor beta-3, and interleukin-1 receptor-like 1 as diagnostic and prognostic biomarkers in renal injuries..
Astute Medical, Inc.
06/18/15
20150166985

Methods for correcting von willebrand factor point mutations


Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a nucleic acid encoding a mutant von willebrand factor protein to correct a point mutation associated with a disease or disorder, e.g., with von willebrand disease. The methods provided are useful for correcting a vwf point mutation within the genome of a cell or subject, e.g., within the human genome.
President And Fellows Of Harvard College
06/18/15
20150166962

Hydrogel-based vascular lineage cell growth media and uses thereof


A medium for growing vascular lineage cells is described. The vascular lineage cell growth medium includes an oligosaccharide-based hydrogel and a growth factor that promotes vascularization by vascular lineage cells..
The Johns Hopkins University
06/18/15
20150166634

Soluble tnf receptors and their use in treatment of disease


The present invention relates to tumor necrosis factor (tnf) antagonists and corresponding nucleic acids derived from tumor necrosis factor receptors (tnfrs) and their use in the treatment of inflammatory diseases. These proteins are soluble secreted decoy receptors that bind to tnf and prevent tnf from signaling to cells.
Roche Innovation Center Copenhagen A/s
06/18/15
20150166622

Fusion proteins for treating metabolic disorders


The invention relates to the identification of fusion proteins comprising polypeptide and protein variants of fibroblast growth factor 21 (fgf21) with improved pharmaceutical properties. Also disclosed are methods for treating fgf21-associated disorders, including metabolic conditions..
06/18/15
20150166614

Polynucleotides and polypeptides in plants


The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed..
Mendel Biotechnology, Inc.
06/18/15
20150166550

Dihydropyridone p1 as factor xia inhibitors


The present invention provides compounds of formula (viii): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor xia inhibitors or dual inhibitors of fxia and plasma kallikrein.
Bristol-myers Squibb Company
06/18/15
20150165802

Media processing device with enhanced media and ribbon loading and unloading features


A device for processing media may include a system and method for loading and unloading consumable supplies of a printer, and more particularly, a system and method for providing a compact form factor printer which provides convenient access to the replaceable components of the printer. A printer may include a base and a lid hingedly attached to the base, moveable between a closed position in which the lid is secured to the base, and an open position.
Zih Corp.
06/18/15
20150165797

Media processing device with enhanced media and ribbon loading and unloading features


A device for processing media may include a system and method for loading and unloading consumable supplies of a media processing device, and more particularly, a system and method for providing a compact form factor media processing device which provides convenient access to the replaceable components of the media processing device. A media processing device may include a base and a lid hingedly attached to the base, moveable between a closed position in which the lid is secured to the base, and an open position.
Zih Corp.
06/18/15
20150165139

Intranasal administration


Intranasal administration of proteins, such as insulin and insulin analogues, in particular immunogenic proteins to the upper posterior region of a nasal cavity of a subject, and in particular the olfactory bulb region.. .
Optinose As
06/18/15
20150165067

Compounds to fibroblast growth factor receptor-3 (fgfr3) and methods of treatment


The invention provides conjugates that consist of a drug moiety agent and a cell binding agent that target human fibroblast growth factor receptor 3 (fgfr3). These conjugates have therapeutic use as they are designed and tailored to target a specific cell population and deliver a powerful cytotoxin inside the cell.
Immunogen, Inc.
06/18/15
20150165023

Methods of administering anti-tnfalpha antibodies


Methods of treating disorders in which tnfα activity is detrimental via biweekly, subcutaneous administration of human antibodies, preferably recombinant human antibodies, that specifically bind to human tumor necrosis factor α (htnfα) are disclosed. The antibody may be administered with or without methotrexate.
Abbvie Biotechnology Ltd.
06/18/15
20150164987

Wnt signaling inhibitor comprising insulin-like growth factor-binding protein


Provided is a novel soluble factor that modulates morphogenesis and cell proliferation, such as cardiac development and/or cardiomyocyte differentiation. Specifically provided are: an inhibitor of wnt signalling, comprising an insulin-like growth-factor-binding protein (igfbp), the protein being binding to a wnt receptor, and/or a polynucleotide encoding the protein; a medicament for prevention and/or treatment of a disease due to enhanced wnt signalling, comprising the inhibitor of wnt signalling, and a medicament for induction of cardiomyocyte differentiation; and a method for prevention and/or treatment of a disease due to enhanced wnt signalling and a method of inducing cardiomyocyte differentiation, the methods each comprising using the inhibitor of wnt signalling, and a cardiomyocyte, which is obtained by the method of inducing cardiomyocyte differentiation, and a use thereof..
National University Corporation Chiba University
06/18/15
20150164961

Methods and compositions for treatment of penile defects


A composition for use in treating penile defects, including erectile dysfunction and peyronie's disease, is provided. The composition includes adipose tissue and stem cells.
06/18/15
20150164956

Muscle-derived cells (mdcs) for treating muscle- or bone-related injury or dysfunction


The present invention provides muscle-derived cells, preferably myoblasts and muscle-derived stem cells, genetically engineered to contain and express one or more heterologous genes or functional segments of such genes, for delivery of the encoded gene products at or near sites of musculoskeletal, bone, ligament, meniscus, cartilage or genitourinary disease, injury, defect, or dysfunction. Ex vivo myoblast mediated gene delivery of human inducible nitric oxide synthase, and the resulting production of nitric oxide at and around the site of injury, are particularly provided by the invention as a treatment for lower genitourinary tract dysfunctions.
University Of Pittsburgh - Of The Commonwealth System Of Higher Education
06/18/15
20150164783

Use of stem cell conditioned medium to induce zo-1 proteins expression for skin regeneration, repair and firming


A use of a stem cell conditioned medium to induce zo-1 proteins expression for skin regeneration, repair and finning is revealed herein. First, mesenchymal stem cells are cultured in a cell culture dish containing complete growth media, wherein the complete growth media include α-mem, fetal bovine serum, and human-basic fibroblast growth factors.
Growgene Biotech Inc.
06/18/15
20150164762

Use of ethanolamine phosphate


A new use of ethanolamine phosphate (ep) in which animal cell function enhancer contains ethanolamine phosphate as an active ingredient. The presence of the ethanolamine phosphate enhances the function of the animal cell even in the absence of serum and growth factors.
Kabushkiki Kaisha Toyota Chuo Kenkyusho
06/11/15
20150162326

Semiconductor package for iii-nitride transistor stacked with diode


One exemplary disclosed embodiment comprises a two-terminal stacked-die package including a diode, such as a silicon diode, stacked atop a iii-nitride transistor, such that a cathode of the diode resides on and is electrically coupled to a source of the iii-nitride transistor. A first terminal of the package is coupled to a drain of the iii-nitride transistor, and a second terminal of the package is coupled to an anode of the diode.
!nternational Rectifier Corporation
06/11/15
20150160784

Compact interactive tabletop with projection-vision


The subject application relates to a system(s) and/or methodology that facilitate vision-based projection of any image (still or moving) onto any surface. In particular, a front-projected computer vision-based interactive surface system is provided which uses a new commercially available projection technology to obtain a compact, self-contained form factor.
Microsoft Corporation
06/11/15
20150160236

Methods for determining anti-tnf therapeutic response


The present invention relates to methods for identifying patients that will respond to treatment with anti-tnf-therapy, i.e., anti-tnf responder patients. In particular, the present invention relates to determining response to an inhibitor of tumor necrosis factor (tnf) in a patient with a chronic inflammatory disease by determining the activity of type i interferon in the patient.
New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery
06/11/15
20150160202

Assays for affinity profiling of nucleic acid binding proteins


Methods, compositions and kits are disclosed for assays to determine the binding affinity of dna-binding proteins or rna-binding proteins for their corresponding recognition site(s). In particular, assays are disclosed for measuring binding affinities when either the binding protein, or the recognition sequence of the recognition site, or cofactor proteins, contain one or more mutations.
Affymetrix, Inc.
06/11/15
20150159818

Linear led illumination device with improved color mixing


A linear multi-color led illumination device that produces uniform color throughout the output light beam without the use of excessively large optics or optical losses is disclosed herein. Embodiments for improving color mixing in the linear illumination device include, but are not limited to, a shallow dome encapsulating a plurality of emission leds within an emitter module, a unique arrangement of a plurality of such emitter modules in a linear light form factor, and special reflectors designed to improve color mixing between the plurality of emitter modules.
Ketra, Inc.
06/11/15
20150159137

Adjuvant for rapid proliferation of human mesenchymal stem cells in vitro, rapid proliferation of human mesenchymal stem cells in vitro, growth factor harvested from rapid proliferation of human mesenchymal stem cells in vitro and use thereof


An adjuvant for rapid proliferation of human mesenchymal stem cells in vitro is provided to overcome the problem of low cell amplification efficiency of human mesenchymal stem cells in a culture process. The adjuvant added for the culture of human mesenchymal stem cells includes at least one antioxidant, and a basic fibroblast growth factor (fgf-2).
Buddhist Tzu Chi Medical Foundation
06/11/15
20150158938

Gremlin-1 antibody


The present invention relates to a gremlin-1 antibody that inhibits gremlin-1 in a manner independent of bone morphogenetic protein (bmp) or vascular endothelial growth factor receptor-2 (vegfr-2), thus providing the effect of treating cancer. The antibody of the present invention inhibits cell migration, cell invasion and cell proliferation which are dependent on gremlin-1, and therefore, can be effectively used in treating cancer or immune disease..
Snu R&db Foundation
06/11/15
20150158930

Factor viii sequences


There is provided a nucleic acid molecule comprising a nucleotide sequence encoding for a functional factor viii protein, wherein the portion of the nucleotide sequence encoding for the b domain of the factor viii protein is between 90 and 111 nucleotides in length and encodes for an amino acid sequence comprising a sequence having at least 85% identity to seq id no: 4 and which comprises six asparagine residues. Also provided is a functional factor viii protein, a vector comprising the above nucleic acid molecule, a host cell, a transgenic animal, a method of treating haemophilia, e.g.
St. Jude Children's Research Hospital
06/11/15
20150158929

Factor viii compositions and methods of making and using same


The present invention relates to compositions comprising factor viii coagulation factors linked to extended recombinant polypeptide (xten), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor viii-related diseases, disorders, and conditions.. .
Biogen Idec Ma Inc.
06/11/15
20150158906

Method of purifying therapeutic proteins


Also provided are solutions and pharmaceutical formulations comprising the fibrinogen and/or factor viii and/or vwf recovered by such methods, and uses thereof.. .
06/11/15
20150157752

Active odor cancellation


The present disclosure relates to methods, devices and systems for calculating or selecting a first set of chemical compounds for an odor additive. For example, a method identifies a second set of chemical compounds present in a sample and intensities of individual chemical compounds in the second set of chemical compounds, and calculates the first set of chemical compounds for the odor additive such that an olfactory perception of a mixture of the sample and the odor additive is an olfactory white..
International Business Machines Corporation
06/11/15
20150157688

Composition and affecting cytokines and nf-kb


The present invention discloses a composition and method for effecting various cytokines and nf-κb by administering an effective amount of a phyto-percolate composition to an individual. In various exemplary embodiments, the composition is claimed to be useful for the effective treatment of inflammation, cancer, and/or various infections including hiv by regulation of various interleukins, such as il-10 and il-2, and of transcription factors including nf-κb..
Zivo Bioscience, Inc.
06/11/15
20150157624

Substituted tetrahydroisoquinoline compounds as factor xia inhibitors


Or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor xia and/or plasma kallikrein which may be used as medicaments..
06/11/15
20150157617

Methods for increasing the stabilization of hypoxia inducible factor-1 alpha


Disclosed herein are methods for controlling the activity of hypoxia-inducible transcription factor 1-alpha (hif-1α) and diseases, conditions, or syndromes related thereto, inter alia, peripheral vascular disease (pvd), coronary artery disease (cad), heart failure, ischemia, and anemia. Further disclosed are pharmaceutical compositions comprising hif-1α prolyl hydroxylase inhibitors useful in treating diseases, conditions, and/or syndromes related thereto the activity of hif-1α..
Aerpio Therapeutics Inc.


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This listing is a sample listing of patent applications related to Factor for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Factor with additional patents listed. Browse our RSS directory or Search for other possible listings.
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