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Factor patents



      
           
This page is updated frequently with new Factor-related patent applications. Subscribe to the Factor RSS feed to automatically get the update: related Factor RSS feeds. RSS updates for this page: Factor RSS RSS


Semiconductor device reliability model and methodologies for use thereof

International Business Machines

Semiconductor device reliability model and methodologies for use thereof

Date/App# patent app List of recent Factor-related patents
04/16/15
20150106967
 Woody plants having improved growth characteristics and  making the same using transcription factors patent thumbnailnew patent Woody plants having improved growth characteristics and making the same using transcription factors
An extensive analytical platform for selecting genes with a possible commercial phenotype from a large group of candidate genes identified using tools in bioinformatics, data from est sequencing and dna array is disclosed. Methods are disclosed for producing a transgenic plant having an increased growth compared to its wild type by altering in the plant the level of a gene product of at least one gene specifically expressed during different phases of wood formation.
Swetree Technologies Ab
04/16/15
20150106962
 Miniature swine transgenic for one or more coagulation factors patent thumbnailnew patent Miniature swine transgenic for one or more coagulation factors
Transgenic swine that express human coagulation factors, e.g., human coagulation factor vii, and/or one or more of human coagulation factors ii, x and xii, and do not express the corresponding porcine coagulation factor or factors, as well as cells, tissues and organs derived therefrom, and their use in transplantation procedures.. .
The General Hospital Corporation
04/16/15
20150106780
 Semiconductor device reliability model and methodologies for use thereof patent thumbnailnew patent Semiconductor device reliability model and methodologies for use thereof
Systems and methods for semiconductor device reliability qualification during semiconductor device design. A method is provided that includes defining performance process window bins for a performance window.
International Business Machines Corporation
04/16/15
20150106589
 Small form high performance computing mini hpc patent thumbnailnew patent Small form high performance computing mini hpc
A computing platform comprising a small form factor high performance computer for mobile high performance computing is provided. The computing platform comprises using small form factor design with a 64-core microprocessor/co-processor is provided.
Remtcs, Inc.
04/16/15
20150106536
 Power-over-ethernet powered universal serial bus charging port patent thumbnailnew patent Power-over-ethernet powered universal serial bus charging port
A power conversion device is configured to convert power-over-ethernet (poe) power to universal serial bus (usb) power to yield a usb charging port. The conversion device can conform to a number of modular and/or portable form factors, allowing existing ethernet data ports to be easily converted to usb charging ports.
Leviton Manufacturing Co., Inc.
04/16/15
20150105838
 Regulation of neurotrophins patent thumbnailnew patent Regulation of neurotrophins
Disclosed are methods for regulating neurotrophin levels within a human body. The invention utilizes an implantable signal generator to deliver stimulation to neural tissue elements.
Functional Neuromodulation, Inc.
04/16/15
20150105390
 Compounds and compositions as protein kinase inhibitors patent thumbnailnew patent Compounds and compositions as protein kinase inhibitors
The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (alk) activity, focal adhesion kinase (fak), zeta-chain-associated protein kinase 70 (zap-70), insulin-like growth factor (igf-1r), or a combination thereof..
Irm Llc, A Delaware Limited Liability Company
04/16/15
20150105321
 Coagulation factor vii polypeptides patent thumbnailnew patent Coagulation factor vii polypeptides
The present invention relates to modified coagulation factor vii polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment..
Novo Nordisk A/s
04/16/15
20150105291
 Method, kit, and  evaluating ischemic heart disease patent thumbnailnew patent Method, kit, and evaluating ischemic heart disease
It is intended to evaluate an ischemic heart disease with high accuracy by convenient operation. The method for evaluating an ischemic heart disease according to the present invention comprises the steps of: assaying complement factor h and/or complement factor d in a sample derived from the blood of a test subject; and comparing the concentration of the complement factor h and/or the concentration of the complement factor d assayed in the preceding step with a reference value(s), wherein it is determined that the seriousness of the ischemic heart disease is high when the concentration falls below the reference value..
Hitachi, Ltd.
04/16/15
20150104871
 Medium comprising transforming growth factor beta 1 and basic fibroblast growth factor patent thumbnailnew patent Medium comprising transforming growth factor beta 1 and basic fibroblast growth factor
The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.. .
Technion Research & Development Foundation Limited
04/16/15
20150104494
new patent

Methods for repair of ear canal tissue defects


Disclosed herein are methods of repairing ear canal tissue defects by administering non-basic fibroblast growth factor (fgf) to the ear canal tissue defect. Also disclosed are delivery devices to administer said non-basic fgf..
New Technologies Holding, Pte. Ltd.
04/09/15
20150100942

Uml model integration and refactoring method


The uml model integration and refactoring method steps include extending the metamodels, composing an integrated uml model derived from the extended metamodels, defining refactoring opportunities and transformation operations during the integrated uml composition, and applying a set of composite refactorings to remove an identified smell from the integrated uml model.. .
King Fahd University Of Petroleum And Minerals
04/09/15
20150100042

Muroid family nasal device


A muroid nasal device for intranasal delivery of compounds to the olfactory region.. .
Impel Neuropharma Inc.
04/09/15
20150099872

Regulation of galactan synthase expression to modify galactan content in plants


The disclosure provides methods of engineering plants to modulate galactan content. Specifically, the disclosure provides methods for engineering a plant to increase the galactan content in a plant tissue by inducing expression of beta-1,4-galactan synthase (gals), modulated by a heterologous promoter.
The Regents Of The University Of Calfornia
04/09/15
20150099701

Modified acidic fibroblast growth factors and composition thereof


The present invention provides acidic fibroblast growth factor (afgf) composition, comprising: (i) afgf of seq id no: 1, (ii) afgf of seq id no: 1 having an n-terminal phosphogluconoylation, (iii) afgf of seq id no: 1 having an n-terminal gluconoylation, (iv) afgf of seq id no: 2 and (v) afgf of seq id no: 3, or a combination thereof. Also provided is a modified acidic fibroblast growth factor (afgf) which has an n-terminal phosphogluconoylation or gluconoylation..
Eu Sol Biotech Co., Ltd.
04/09/15
20150099699

Conjugates of insulin-like growth factor-1 and poly(ethylene glycol)


A conjugate consisting of an insulin-like growth factor-1 (igf-i) variant and one or two poly(ethylene glycol) group(s), characterized in that said igf-i variant has an amino acid alteration at up to three amino acid positions 27, 37, 65, 68 of the wild-type igf-i amino acid sequence so that one or two of said amino acids is/are lysine and amino acid 27 is a polar amino acid but not lysine, is conjugated via the primary amino group(s) of said lysine(s) and said poly(ethylene glycol) group(s) have an overall molecular weight of from 20 to 100 kda is disclosed. This conjugate is useful for the treatment of neurodegenerative disorders like alzheimer's disease..
Hoffmann-la Roche Inc.
04/09/15
20150099298

Antibodies capable of binding to the coagulation factor xi and/or its activated form factor xia and uses thereof


The present invention relates to antibodies capable of binding to the coagulation factor xi and/or its activated form factor xia and methods of use thereof, particularly methods of use as agents inhibiting platelet aggregation and by this inhibits thrombus formation.. .
Bayer Pharma Aktiengesellschaft
04/09/15
20150099034

Low-calorie, low-fat cracker composition containing xylose, cracker made from the composition, and preparing the composition


The present invention relates to a cracker composition containing xylose, to a cracker made from the composition, and to a method for preparing the composition, wherein xylose is included not only to achieve excellent coloring and gloss even without spraying oils and fats on the surface of the cracker, but to also provide a low-calorie, low-fat cracker with an excellent, light and simple taste. More particularly, the present invention relates to a cracker composition containing xylose, to a cracker made from the composition, and to a method for preparing the composition, wherein the cracker is prepared from a composition that contains xylose rather than spraying oils and fats on the surface of the cracker which would lead to the uptake of a high amount of fat and calories, to thereby provide a cracker which has a superior appearance and olfactory and gustatory characteristic, which is healthy, and which can be used as a snack for weight control.
Cj Cheiljedang Corporation
04/09/15
20150098950

Liquid formulations of tumor necrosis factor-binding proteins


The invention relates to a stable, pharmaceutically acceptable, aqueous formulation of tnf-binding protein, comprising a tnf-binding protein, a buffer and an isotonicity agent.. .
Ares Trading S.a.
04/09/15
20150098698

Ultra-compact, software-defined fiber optic patch-panels


An automated, robotic patch-panel system in a highly compact form factor implementing knots and braids switching algorithms is disclosed. This system incorporates stacked layers of connector ports, each row of connector ports defining an arc with a radius of curvature, wherein the radius of curvature is substantially larger than the total height of the stacked layers.
Telescent Inc.
04/09/15
20150098536

N factorial dual data rate clock and data recovery


System, methods and apparatus are described that facilitate transmission of data over a multi-wire data communications link, particularly between two devices within an electronic apparatus. Each symbol in a sequence of symbols received from a plurality of signal wires is received in an odd transmission interval or an even transmission interval.
Qualcomm Incorporated
04/09/15
20150097437

System and increasing efficiency of gensets in micro-grid systems


A system and method for running a plurality of gensets in parallel in a micro-grid system is disclosed. The system and method may include at least one genset configured to run at a load factor of greater than sixty percent, the number of the at least one genset supplying power at any given time including a minimum or less than minimum number of gensets capable of meeting a demand imposed by a load.
Caterpillar Inc.
04/02/15
20150096082

Expression of the human igf-1 in transgenic plastids


A plastid transformation vector for stably transforming a plastid genome, comprising, as operably-linked components, a first flanking sequence, a dna sequence coding for synthetic insulin-like growth factor-1 (igf-1s) (seq id no. 1) or a substantially homologous dna sequence of igf-1s, which is capable of expression in the plastid genome, and a second flanking sequence..
University Of Central Florida Research Foundation, Inc.
04/02/15
20150095489

Storage management device and control method


An operation management server that manages a storage apparatus in which volumes are included and data is sent and received via transmission resources is provided. The operation management server includes a setting unit that sets a target value of the performance to some or all of the volumes; a monitoring unit that monitors the load factor of the transmission resources; and a bandwidth management unit that specifies a target transmission resource on the basis of the load factor of the transmission resources, that decides, on the basis of the target value, bandwidth allocation of some of the volumes that use the specified transmission resource, and that instructs a bandwidth control unit in the storage apparatus to adjust the bandwidth on the basis of the decided bandwidth allocation..
Fujitsu Limited
04/02/15
20150094982

Method for determining the estimated weight of an aircraft and corresponding system


A method for determining an estimated mass of an aircraft is provided. This method includes determining a first mass of the aircraft, from characteristics of the aircraft determined before or after takeoff of the aircraft, determining, during the flight of the aircraft, a second mass of the aircraft, from a lift equation of the aircraft expressing the mass of the aircraft as a function of information representative of the load factor of the aircraft, of a lift coefficient of the aircraft, of speed information of the aircraft and of a static pressure of a mass of air passed through by the aircraft, determined from measurements by sensors of the aircraft during the flight of the aircraft, evaluating the estimated mass at said determination moment, as a function of said first and second masses..
Dassault Aviation
04/02/15
20150094358

Treatment of hepatocyte growth factor (hgf) related diseases by inhibition of natural antisense transcript to hgf


The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of hepatocyte growth factor (hgf), in particular, by targeting natural antisense polynucleotides of hepatocyte growth factor (hgf). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of hgf..
Curna, Inc.
04/02/15
20150093833

Method of pre-treating a filter used in a small-scale water separometer


The safety and proper performance of jet aircraft engines requires that any contamination of jet fuel, for example by water or by improper contaminants, be filtered (removed) before delivery of the fuel, through hoses, to the fuel tanks of the aircraft. Coalescing devices and filters in the fuel delivery system are used to attain this result.
D-2, Inc.
04/02/15
20150093762

Hepatic stellate cell precursors and methods of isolating same


The present invention relates to precursor cells to hepatic stellate cells, compositions comprising same and methods of isolating same. The surface antigenic profile of the precursors is mhc class ia negative, icam-1+, vcam-1+, β3-integrin+.
University Of North Carolina At Chapel Hill
04/02/15
20150093590

Method of manufacturing a part with a high quality surface finish and complex internal geometry


A structural member having an internal geometry capable of receive an object and substantially seamless outer surfaces, and that is obtainable by a method that includes providing several small plates, welding together the small plates, removing the weld residue, and polishing an outer surface of the structural member to achieve a certain desired visual effect. A middle plate, or several middle plates, may be positioned between a first plate and a second plate.
Apple Inc.
04/02/15
20150093448

Methods and compositions for diagnosis and prognosis of renal injury and renal failure


The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of angiopoietin-related protein 3, soluble lymphatic vessel endothelial hyaluronic acid receptor 1, and vascular endothelial growth factor d as diagnostic and prognostic biomarkers in renal injuries..
Astute Medical, Inc.
04/02/15
20150093395

Anti-fxi antibodies and methods of use


Disclosed herein are monoclonal antibodies specific for factor xi (fxi) that prevent activation of fxi by factor xiia (fxiia). The monoclonal antibodies are universal fxi antibodies, capable of binding all mammalian species tested.
Oregon Health & Science University
04/02/15
20150093386

Multi-functional antibody polypeptide for cryptic epitope of epidermal growth factor receptor and t cell antigen


(b) a second functional domain, specifically recognizing the surface antigen of a human t cell.. .
04/02/15
20150093353

Method and system for treatment of damaged biological tissue


Biomaterial compositions comprising extracellular matrix (ecm) and an ecm-mimicking biomaterial, such as poly(glycerol sebacate) (pgs), for treating damaged biological tissue; particularly, damaged cardiovascular tissue. The biomaterial compositions can also include additional biologically active agents, such as growth factors, and polymeric materials, such as polyepsilon-caprolactone (pcl)..
Cormatrix Cardiovascular, Inc.
04/02/15
20150092969

Power and signal transmission devices for auditory prosthesis


An auditory prosthesis can be powered by an on-board battery that is placed into a receptacle in the auditory prosthesis. When longer battery life is desired, a recipient can selectively utilize a discrete power supply to power the auditory prosthesis.
04/02/15
20150092335

Frictional hinge for electronic devices


A frictional hinge assembly for use with electronics devices such as computer notebooks having base and lid portions may present a higher level of frictional resistance to rotation in one direction than in the other. The hinge may comprise a base-mounted helical sleeve having loops that embrace a rotational shaft that is connected to a lid.
04/02/15
20150092323

Control buttons for notebooks and convertible devices


A keyboard or keyboard unit comprises an upper surface and a lower surface, and a front edge. An array of keys is disposed on the upper surface.
04/02/15
20150091687

Winding and preparing a winding applied to an inductive device


The present invention relates to a winding and a method for preparing a winding of inductive devices. The winding includes at least a plurality of layers, where each layer includes at least one conductive loop; the conductive loops are electrically connected to form a winding; and the conductive loop or the portion of the conductive loop of at least one layer is not spatially aligned with the conductive loop or the portion of the conductive loop of at least one another layer.
Montage Technology (shanghai) Co., Ltd.
04/02/15
20150090012

System for pre-treating a filter used in a small-scale water separometer


The safety and proper performance of jet aircraft engines requires that any contamination of jet fuel, for example by water or by improper contaminants, be filtered (removed) before delivery of the fuel, through hoses, to the fuel tanks of the aircraft. Coalescing devices and filters in the fuel delivery system are used to attain this result.
D-2, Inc.
03/26/15
20150089288

Technique for establishing an audio socket debug connection


A debug controller monitors a tip-ring-ring-shield (trrs) socket, within a form factor device, to detect whether a debug unit is transmitting a request for a trrs socket debug connection. The form factor device also includes a system on chip (soc), a switch, and an audio codec.
Nvidia Corporation
03/26/15
20150088620

System and reminding and tracking use of reusable container and carry products


The present disclosure relates to a system and method for reminding users to use, and for tracking usage of, reusable container and carry products such as reusable bags, boxes, cups, cup sleeves, and bottles, especially for food and beverages. In an aspect, the system and method provides an identification module which may be attached to or embedded within a reusable container or carry product.
03/26/15
20150088222

Ingestible, electrical device for stimulating tissues in a gastrointestinal tract of an organism


In one aspect, an ingestible, electrical device, comprises one or more electrodes comprising a biocompatible conducting material and a biocompatible insulating material; a generator connected to the one or more electrodes; and an outer casing enclosing the one or more electrodes and the generator, the outer casing configured to dissolve in an aqueous environment of the organism; wherein the one or more electrodes have a first form factor when enclosed in the outer casing and a second form factor following a dissolution of the outer casing, the first form factor is a form factor that is collapsed an increased amount relative to an amount that the second form factor is collapsed, and the second form factor is a form factor that is collapsed a decreased amount relative to an amount that the first form factor is collapsed.. .
Carnegie Mellon University
03/26/15
20150087597

Polypeptides and methods of use


Described herein are fragments of fibronectin and vitronectin and variants thereof that have certain activities, including growth factor-binding activity. Also described are fragments of growth factors that bind to fibronectin and inhibit binding of full-length growth factors to fibronectin.
The Research Foundation For The State University Of New York
03/26/15
20150087593

Coagulation factor viii with reduced immunogenicity


B. Modification of said epitope(s) by eliminating at least one hydrophobic aminoacid residues in position p1 and/or p7, substituting at least one hydrophobic aminoacid residue in position p1 and/or p7 with a non-hydrophobic residue, or adding a non-hydrophobic residue in position p1 and/or p7..
03/26/15
20150087062

System and electrospun biodegradable scaffold for bone repair


This invention relates a structure and system for growth factor incorporation which can improve the osteogenic differentiation of hmscs, for potential bone regeneration and bone growth applications or used alone for bone repair or growth applications. The system comprises a biodegradable polyester, a hydrophilic polymer, a growth factor and optionally a bioceramic..
03/26/15
20150087060

Method for inducing erythropoietin-producing cell


An object of the present invention is to provide a method for inducing the differentiation of erythropoietin-producing cells from human pluripotent stem cells. The above object is achieved by providing a method for inducing the differentiation of erythropoietin-producing cells from human pluripotent stem cells using a medium containing a specific growth factor and a specific compound..
Kyoto University
03/26/15
20150087058

Stem cell culture medium and culturing stem cells using same


The present invention relates to a stem cell culture medium which can be substituted for a conventional stem cell culture medium containing the heterologous protein fetal bovine serum, and more particularly to a stem cell culture medium containing a basal medium and a knockout serum replacement and a method of culturing stem cells using the same. According to the invention, a high purity of stem cells having a reduced ability to spontaneously differentiate can be obtained without having to use the heterologous protein fetal bovine serum and expensive growth factors (egf and bfgf), and thus the efficacy of stem cell therapy can be significantly increased..
Samsung Life Public Welfare Foundation
03/26/15
20150086616

Method for the prevention and treatment of alzheimer's disease


Oral non-steroidal anti inflammatory drugs (nsaids) are not an effective treatment of alzheimer's disease, because the brain dose is too low. Nasal delivery of nsaids such as ibuprofen, flurbiprofen, indomethacin, diclofenac, or naproxen, which inhibit the enzymes cyclooxygenase-1 (cox-1) and cox-2, are used to prevent and/or treat alzheimer's disease, a low grade brain inflammation.
03/26/15
20150086547

Combination therapy for treating breast cancer


The invention provides compositions and methods for treating breast cancer. Specifically, the invention relates to administering a transforming growth factor beta (tgfβ) antagonist in combination with capecitabine and ixabepilone to treat breast cancer..
Genzyme Corporation
03/26/15
20150086214

Tuning device for pluggable optical transceivers


A tuning device for a pluggable xfp and sfp+ and dwdm transceiver devices. Also provided are applications for cwdm xfp, and sfp+ and future form factors as well as dwdm and cwdm sfp.
Champion Optical Network Engineering, Llc
03/26/15
20150086175

Integrated video and audio recording and transmission


A device includes a body-worn camera and small form factor digital video recorder that is integrated with a wireless microphone and transmitter that interoperates with an in-car video system.. .
Mobile-vision, Inc.
03/19/15
20150082281

System and providing access to data in a plurality of software development systems


Systems and method are provided for determining risk of product release failure in an environment where multiple independent releases come together into a shared environment. A risk factor for success or failure of a product release is based on release information input by a user and information input by other users regarding releases, the users typically on distinct development systems.
Fmr Llc
03/19/15
20150080785

Alzheimer's disease treatment with multiple therapeutic agents delivered to the olfactory region through a special delivery catheter and iontophoresis


This invention describes the administration of multiple therapeutic agents with insulin in conjunction with bexarotene, ketamine, monoclonal antibodies etanercept, igf-1, and acetylcholine esterase inhibitors physostigmine, for treatment of alzheimer's disease and other neurodegenerative diseases. Insulin, improves memory; also augments and amplifies the effects of the adjuvant therapeutic agents (paracrine and intracrine effects) and consequently reduces the β amyloid, its soluble precursors, prevents damage to the neuronal skeletal network (taupathy), and blocks glutamate excitotoxicity, reduces brain inflammation, prevents apoptosis, and increases the acetylcholine levels in the neurons and synapses; by using a combination of insulin, bexarotene, ketamine, etanercept, igf-1, and physostigmine therapeutic agents.
Wedge Therapeutics, Llc
03/19/15
20150080475

Memantine protects inflammation-related degeneration of dopamine neurons through inhibition of over-activated microglia and release of neurotrophic factors from astroglia


This invention relates to a method of treating opiate addiction caused by microglial over-activation-mediated dopamine (da) neurons damage, comprising administering a human in need of such treatment 0.01-0.08 mg/kg of 1-amino-3,5-dimethyladamantane hydrochloride orally per day.. .
03/19/15
20150080455

Treatment of transcription factor e3 (tfe3) and insulin receptor substrate 2 (irs2) related diseases by inhibition of natural antisense transcript to tfe3


The present invention relate to antisense oligonucleotides that modulate the expression of and/or function of transcription factor e3 (tfe3) and/or insulin receptor substrate 2 (irs2) polynucleotides, in particular, by targeting natural antisense polynucleotides of transcription factor e3 (tfe3) and/or insulin receptor substrate 2 (irs2). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of tfe3 and/or irs2..
Curna, Inc.
03/19/15
20150080306

Therapeutic agents comprising elastic peptides


The present invention provides therapeutic agents and compositions comprising elastic peptides and therapeutic proteins. Such peptides exhibit a flexible, extended conformation.
Duke University
03/19/15
20150080304

Treatment and prevention of radiation injury using mfg-e8


Methods and compositions are disclosed for treating and preventing radiation injury using milk fat globule epidermal growth factor-factor viii (mfg-e8).. .
The Feinstein Institute For Medical Research
03/19/15
20150080300

Growth factor concentrate and the use thereof


Provided herein are growth factor concentrates, cosmetic compositions and methods for cosmetic treatment. The growth factor concentrates comprise decapsulated growth factors derived from platelet rich plasma..
Bestop Group Holdings Limited


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