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Factor patents



      

This page is updated frequently with new Factor-related patent applications.




Date/App# patent app List of recent Factor-related patents
06/23/16
20160182603 
 Browser display casting techniques patent thumbnailnew patent Browser display casting techniques
Browser display casting techniques are described. In one or more implementations, content is displayed within a browser on a display device of a mobile communications device, the mobile communications device having a form factor configured to be held by one or more hands of a user.

06/23/16
20160182235 
 General encoding functions for modular exponentiation encryption schemes patent thumbnailnew patent General encoding functions for modular exponentiation encryption schemes
Various embodiments relate to a method of encoding data and related device and non-transitory machine readable storage medium, the method including: determining a set of digits, x, representative of a value to be encoded; determining a set of factor values, s, to be used in generating an encoded value, wherein the set of factor values, s, is a set of input value factors for a modular exponentiated digital signature process; for a given digit, x, of the set of digits, x, determining at least one factor value, s, of the set of factor values, s, corresponding to the given digit, x; and including the at least one factor value, s, in an encoded value.. .

06/23/16
20160182037 
 Resonant radio frequency switch patent thumbnailnew patent Resonant radio frequency switch
An spdt switch in a rf communication transceiver provides for choosing the transmit/receive path for the rf signal. It consists of the series and shunt branches each consisting of stack of fets.

06/23/16
20160181145 
 Land side and die side cavities to reduce package z-height patent thumbnailnew patent Land side and die side cavities to reduce package z-height
A package structure including a capacitor mounted within a cavity in the package substrate is disclosed. The package structure may additionally include a die mounted to a die side surface of the package substrate, and the opposing land side surface of the package substrate may be mounted to a printed circuit board (pcb).

06/23/16
20160180130 
 Mini-barcode reading module with flash memory management patent thumbnailnew patent Mini-barcode reading module with flash memory management
A miniature barcode reading module for an electronic device minimizes the size of the memory of the processor die allowing the module to be used in small form factor electronic devices. The module may include an image sensor package operative to scan a barcode and a processor die coupled to the image sensor package.

06/23/16
20160179653 
 Source code equivalence verification device and source code equivalence verification method patent thumbnailnew patent Source code equivalence verification device and source code equivalence verification method
When verifying rapidly the equivalence between source codes with respect to refactoring, the present invention performs two types of verification: verification based on structural comparison using structure graphs obtained by analyzing the source codes, and verification based on symbolic execution. If the structural comparison using the structure graphs can verify that the structures are identical with each other, then symbolic execution is not performed.

06/23/16
20160179504 
 Refactoring data flow applications without source code changes or recompilation patent thumbnailnew patent Refactoring data flow applications without source code changes or recompilation
Systems and methods may provide refactoring data flow applications without source code changes or recompilation. An apparatus may create a map file that describes how an original graph structure and node properties are mapped to a new structure and set of properties.

06/23/16
20160178904 
 Nausea and seizure detection, prediction, and mitigation for head-mounted displays patent thumbnailnew patent Nausea and seizure detection, prediction, and mitigation for head-mounted displays
Technologies for mitigating a physiological condition include a wearable computing device coupled with a head-mounted display and sensor(s). The wearable computing device may receive sensor data indicative of a physical attribute of the user while displaying information on the head-mounted display.

06/23/16
20160178653 
 Cartridge for storing biosample capillary tubes and use in automated data storage systems patent thumbnailnew patent Cartridge for storing biosample capillary tubes and use in automated data storage systems
Embodiments of the disclosure relate to methods of storing and using biosamples with a cartridge that includes slots for storing biosample capillary tubes. The methods include providing access to a holder inside an enclosure of the cartridge, the enclosure having a same form factor as a data tape cartridge used in an automated tape library.

06/23/16
20160178648 
 Marker for detecting proliferation and treatment capacities of adipose-derived stem cell cultured in medium containing egf or bfgf, and use thereof patent thumbnailnew patent Marker for detecting proliferation and treatment capacities of adipose-derived stem cell cultured in medium containing egf or bfgf, and use thereof
The present invention relates to: a composition for detecting a marker for detecting the proliferation capacity or treatment capacity of adipose-derived stem cells cultured in a medium containing epidermal growth factor (egf) or basic fibroblast growth factor (bfgf); and a detection method.. .

06/23/16
20160178615 
new patent

Rgd-binding compounds and methods of use


Provided herein are compositions and methods for preventing and treating diseases and risk factors associated with metabolic syndrome by targeting the rgd-binding site of selected intra- and extracellular proteins. Exemplary compositions include rgd-polyphenol conjugates via an ester linkage; polyphenol polymer conjugated to rgd analogs or mimetics; and rgd polymer conjugates linked to polyphenol..

06/23/16
20160177286 
new patent

Gla-domainless factor x


The present invention relates to a protein consisting of the sequence seq id no.: 11 or 25 or 26, directly bound, or bound via a linker, especially -arg-lys-arg-, to the sequence seq id no.: 6.. .

06/23/16
20160176958 
new patent

Tnf-alpha binding proteins


Isolated binding proteins, e.g., antibodies or antigen binding portions thereof, which bind to tumor necrosis factor-alpha (tnf-α), e.g., human tnf-α, and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies..

06/23/16
20160176879 
new patent

Novel hydroximic acid derivative and medical application thereof


The present invention relates to a kind of new hydroximic acid derivatives, in particular, hydroximic acid derivatives of pyrazolopyrimidine and their medical applications, which have inhibition to histone deacetylase 1 and two kinds of tyrosine kinases (vascular endothelial cell growth factor receptors as well as platelet-derived growth factor receptors) simultaneously, and thus can be used for treatment of diseases related to those three kinds of enzymes. This kind of compounds both exerts a synergistic effect sufficiently to increase biological activity, and avoids problems caused by different properties and metabolisms, therefore is more practical and has good prospects..

06/23/16
20160176522 
new patent

Method and a system for determining an angular velocity in turning for a rotary wing aircraft


A method and a system for determining an angular velocity in turning for a rotary wing aircraft in order to make turns that are coordinated relative to the ground or else relative to the air and in order to manage the transition between ground coordination and air coordination while taking account of the wind to which said aircraft is subjected. Said method serving to determine an angular velocity in yaw by means of an anticipation value a and a correction value b on the basis in particular of speeds of advance of the aircraft relative to the ground vasol and relative to the air vaair, of its lateral acceleration gy and of its lateral load factor ny..

06/23/16
20160175929 
new patent

Process for additive manufacturing of parts by melting or sintering particles of powder(s) using a high-energy beam with powders adapted to the targeted process/material pair


A method of fabricating parts out of metallic, intermetallic, ceramic, ceramic matrix composite, or metal matrix composite material with discontinuous reinforcement, includes melting or sintering powder particles by means of a high-energy beam. The powder used is a single powder of particles that present sphericity lying in the range 0.8 to 1.0 and of form factor lying in the range 1 to √2, each powder particle presenting substantially identical mean composition, and the grain size distribution of the particles of the powder is narrowed around the mean diameter value d50% in such a manner that: (d90%−d50%)/d50%≦0.66; and (d50%−d10%)/d50%≦0.33; with a “span”: (d90%−d10%)/d50%≦1.00..

06/23/16
20160175642 
new patent

Seated exercise apparatus


A seated exercise apparatus comprises a frame having a seat attached to the frame. A pair of opposed cranks are rotatably coupled to the frame such that they rotate about a first axis.

06/23/16
20160175439 
new patent

Vegf antagonist formulations


Formulations of a vascular endothelial growth factor (vegf)-specific fusion protein antagonist are provided including a pre-lyophilized formulation, a reconstituted lyophilized formulation, and a stable liquid formulation. Preferably, the fusion protein has the sequence of seq id no:4..

06/23/16
20160175402 
new patent

Polymer-factor viii moiety conjugates


Conjugates of a factor viii moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof.

06/23/16
20160175263 
new patent

Pharmaceutical composition for preventing or treating diabetes mellitus, preventing or treating diabetes mellitus, and screening for diabetes mellitus therapeutic agent


Provided are a pharmaceutical composition including geraniol or a pharmaceutically acceptable salt thereof as an active ingredient for use in preventing or treating diabetes mellitus, a method of preventing or treating diabetes mellitus or a complication due to diabetes mellitus of an individual, in which the method includes administering the individual with a pharmaceutical composition comprising geraniol or a pharmaceutically acceptable salt thereof as an active ingredient and inducing an olfactory stimulation to the individual using the pharmaceutical composition, and a screening method of an antidiabetic agent that may include contacting a cell expressing an olfactory receptor with a test material; measuring a level of expression of glucagon-like peptide-1 (glp-1) secreted from the cell; and determining the test material, when the test material promotes expression of glp-1, as a candidate material of an antidiabetic agent. In addition, a quasi-drug composition and a cosmetic composition including geraniol for uses are provided..

06/23/16
20160175225 
new patent

Peptides and their use in the treatment of skin


Embodiments of the invention are related generally to the methods of diminishing the signs of aging in and/or improving health of human integuments, such as skin, and compositions comprising peptides useful therefor. The compositions according to the invention may comprise one or more peptides or fragments or derivatives thereof derived from a growth factor, e.g., growth differentiation factor 11 (gdf11), in a topically acceptable vehicle..

06/16/16
20160174408 

Heat sink for a square camera


A camera having a substantially cubic form factor comprises, among other components, an image sensor, a lens assembly, a printed circuit board, and a heat sink. A heat sink operates to provide a thermally conductive path to an external surface of the camera.
Gopro, Inc.


06/16/16
20160173833 

Video delivery systems using wireless cameras


Systems, apparatuses, and techniques for video delivery can include one or more of the following: a wireless camera arranged in a wearable form factor comprising a battery to provide energy, and configured to generate a video feed, and a base station in wireless communication with the wireless camera and configured to receive the video feed from the wireless camera and process the video feed, and a video portal device communicatively coupled with the base station and configured to receive the processed video feed from the base station and deliver at least a portion of the processed video feed to one or more remote clients. A base station can reserve a wireless channel for the wireless camera for a video transmission..
Micropower Technologies, Inc.


06/16/16
20160173311 

Communication device with power amplifier crest factor reduction


Various embodiments include a power amplifier with crest factor reduction embodied by first circuitry for producing a correlated out-of-band noise signal for controlling the adjacent channel leakage ratio (aclr) of a communication device; and second circuitry for providing an output signal for controlling the error vector magnitude (evm) of a digital radio. The aclr and the evm are concurrently individually controllable.

06/16/16
20160172283 

Power semiconductor package having reduced form factor and increased current carrying capability


A power semiconductor package is disclosed. The power semiconductor package includes a leadframe having partially etched segments and at least one non-etched segment, a first semiconductor die having a first power transistor and a driver integrated circuit (ic) monolithically formed thereon, a second semiconductor die having a second power transistor, wherein the first semiconductor die and the second semiconductor die are configured for attachment to the partially etched segments, and wherein the partially etched segments and the at least one non-etched segment enable the first semiconductor die to be coupled to the second semiconductor die by a legless conductive clip..
Infineon Technologies Americas Corp.


06/16/16
20160172279 

Integrated power assembly with reduced form factor and enhanced thermal dissipation


An integrated power assembly is disclosed. The integrated power assembly includes a printed circuit board, a first leadframe having partially etched segments and non-etched segments on the printed circuit board, a first semiconductor die configured for attachment to the partially etched segments of the first leadframe, a second leadframe having a legless conductive clip, and a second semiconductor die situated over the first semiconductor die and being coupled to the first semiconductor die by the legless conductive clip..
Infineon Technologies Americas Corp.


06/16/16
20160171862 

Dynamic virtual fencing for a hazardous environment


A method and system for automatically generating dynamic virtual fences in a hazardous environment are provided. The method includes detecting a potential hazard associated with a field object in the hazardous environment.

06/16/16
20160171487 

System and pre-provisioned wearable contactless payments


Systems and methods may comprise rfid data acquisition technology which may be embedded in a fob or tag for use in completing financial transactions. This fob may a self-contained device which includes a transponder and which may be contained on any portable form factor.
American Express Travel Related Services Company, Inc.


06/16/16
20160171482 

System and over the air provisioned wearable contactless payments


Systems and methods may comprise rfid data acquisition technology which may be embedded in a fob or tag for use in completing financial transactions. This fob may a self-contained device which includes a transponder and which may be contained on any portable form factor.
American Express Travel Related Services Company, Inc.


06/16/16
20160169911 

Marker for statin treatment stratification in heart failure


The present invention is directed to a method of identifying a patient having heart failure as likely to respond to a therapy comprising a statin. The method is based on measuring the level of at least one marker selected from gdf-15 (growth differentiation factor 15), urea, shbg (sex hormone-binding globulin), uric acid, plgf (placental growth factor), il-6 (interleukin-6), transferrin, a cardiac troponin, sflt-1 (soluble fms-like tyrosine kinase-1), prealbumin, ferritin, osteopontin, sst2 (soluble st2), and hscrp (high sensitivity c-reactive protein) in a sample from a patient.
Roche Diagnostics Operations, Inc.


06/16/16
20160169851 

Apparatus and judging sensibility of smell


An electronic nose apparatus is capable of replacing the olfactory sense of human. An apparatus and method for judging sensibility of a smell form olfactory characteristics of smells as data and judge the type and intensity of the smell based on the data.
Hyundai Motor Company


06/16/16
20160168572 

Delivery of therapeutic agent


A method of producing nanovesicles comprising an oligonucleotide inhibitor to an oncogene or a proto-oncogene or the gene product thereof, said method comprises a) introducing a dna sequence encoding an oligonucleotide capable of inhibiting a human oncogenic or proto-oncogenic transcription factor, into a mammalian cell; b) allowing the cell to express said inhibitor oligonucleotide; and c) obtaining nanovesicles containing said inhibitor oligonucleotide from said cell. Nanovesicles produced by the claimed method can be effectively and specifically targeted to e.g.
Vl27,inc.


06/16/16
20160168538 

Flk1+ and ve-cadherin+ endothelial cells derived from ips or es cells, and methods of preparing and using the same


This invention provides endothelial cells expressing transcription factor er71/etv2, and cell surface endothelial markers flk1 and ve-cadherin prepared from induced pluripotent stem cells or embryonic stem cells, as well as methods of preparing the cells and methods of using the cells to vascularize and re-endothelialize or repair ischemic tissue in a subject.. .
The Board Of Trustees Of The University Of Illinois


06/16/16
20160168222 

Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases


The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fgf19 and/or fgf21, and variants or fusions of fgf19 and/or fgf21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.. .
Ngm Biopharmaceuticals, Inc.


06/16/16
20160168221 

Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases


The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fgf19 and/or fgf21, and variants or fusions of fgf19 and/or fgf21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.. .
Ngm Biopharmaceuticals, Inc.


06/16/16
20160168220 

Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases


The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fgf19 and/or fgf21, and variants or fusions of fgf19 and/or fgf21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.. .
Ngm Biopharmaceuticals, Inc.


06/16/16
20160168219 

Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases


The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fgf19 and/or fgf21, and variants or fusions of fgf19 and/or fgf21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.. .
Ngm Biopharmaceuticals, Inc.


06/16/16
20160168218 

Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases


The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fgf19 and/or fgf21, and variants or fusions of fgf19 and/or fgf21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.. .
Ngm Biopharmaceuticals, Inc.


06/16/16
20160168217 

Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases


The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fgf19 and/or fgf21, and variants or fusions of fgf19 and/or fgf21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.. .
Ngm Biopharmaceuticals, Inc.


06/16/16
20160168216 

Methods of using compositions comprising variants and fusions of fgf19 polypeptides for reducing glucose levels in a subject


The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fibroblast growth factor 19 (fgf19) and/or fibroblast growth factor 21 (fgf21), and variants or fusions of fibroblast growth factor 19 (fgf19) and/or fibroblast growth factor 21 (fgf21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.. .
Ngm Biopharmaceuticals, Inc.


06/16/16
20160168215 

Compositions comprising variants and fusions of fgf19 polypeptides


The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fibroblast growth factor 19 (fgf19) and/or fibroblast growth factor 21 (fgf21), and variants or fusions of fibroblast growth factor 19 (fgf19) and/or fibroblast growth factor 21 (fgf21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.. .
Ngm Biopharmaceuticals, Inc.


06/16/16
20160168154 

Inhibitors of transcription factors and uses thereof


The present invention provides novel compounds of any one of formulae (i) to (iv), and pharmaceutically compositions thereof. Compounds of any one of formulae (i) to (iv) are believed to be inhibitors of bromodomain-containing proteins (e.g., bromo and extra terminal proteins (bets)).
University Of Massachusetts


06/16/16
20160167454 

Run-flat, puncture-proof tire structure


An improvement in run-flat, puncture-proof tire structure, in which the foamed inner tire body is formed of foam structure, which can provide the required softness/hardness for the tire by adjusting the proportion of foam material ingredients, and since the foamed inner tire body can be placed in the tire body hollow portion of the outer tire body, therefore it avoids blowout when a sharp object enters into and punctures the outer tire body, and it reduces the risk factors during motion, and the rim section positioned on the wheel rim body holds the inflatable inner tire body, and the inflatable inner tire body is also pressed up against the foamed inner tire body to absorb the vibration formed on the wheel rim body during motion, and since the problems of repair requirement and sudden blowout are still present after a puncture, it provides safety and stability during motion.. .

06/16/16
20160166735 

Injectable composition for in-situ repair and regeneration of an injured ligament or tendon and methods of use


The invention provides an injectable composition and method for the minimally invasive, in-situ repair and regeneration of an injured ligament or tendon in a mammalian subject. The composition is also useful for the delivery of growth factors, therapeutic agents and cells into the area of tendon or ligament injury..
The Board Of Trustees Of The Leland Stanford Junior University


06/16/16
20160166730 

Biocompatable annular prostheses and methods for forming same


Annular prostheses comprising an elongated tubular member formed from an extracellular matrix (ecm) composition comprising ecm from a mammalian tissue source, which, when disposed proximate damaged cardiovascular tissue, induces modulated healing, including modulation of inflammation and bioremodeling. The ecm can also be augmented with a supplemental biologically active agent, such as a growth factor, to enhance modulation of inflammation and bioremodeling..
Cormatrix Cardiovascular, Inc.


06/16/16
20160166667 

Divalent vaccine compositions and the use thereof for treating tumors


The invention describes vaccine compositions combined in the same proportion with the extracellular domains of growth factor receptors her1 and her2 or fragments thereof and furthermore very small size proteoliposomes derived from proteins of the outer membrane of neisseria meningitidis and gm3 ganglioside (vssp-gm3), administered subcutaneously. The disclosed compositions, which induce the production of antibodies are used for the treatment of malignancies and offer advantages because they completely remove the tumor mass thus preventing tumor regression due to the emergence of resistant variants..
Centro De Inmunologia Molecular


06/16/16
20160166660 

Combination therapy using a factor xii inhibitor and a c-1 inhibitor


Methods and compositions are disclosed for treating disorders of the contact activation system, comprising the administration of at least one c1-inhibitor (c1-inh) and at least one factor xii (fxii) inhibitor.. .
Csl Behring Gmbh


06/16/16
20160166657 

Factor ix polypeptides and methods of use thereof


The present invention provides methods of administering factor ix; methods of administering chimeric and hybrid polypeptides comprising factor ix; chimeric and hybrid polypeptides comprising factor ix; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.. .
Biogen Hemophilia Inc.


06/16/16
20160166642 

Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases


The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fgf19 and/or fgf21, and variants or fusions of fgf19 and/or fgf21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.. .
Ngm Biopharmaceuticals, Inc.


06/16/16
20160166633 

Methods and compositions for the prevention and treatment of friedreich's ataxia


The disclosure provides methods of preventing or treating friedreich's ataxia in a mammalian subject, reducing risk factors, signs and/or symptoms associated with friedreich's ataxia, and/or reducing the likelihood or severity of friedreich's ataxia. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to e.g., reduce oxidative stress, increase mitochondrial metabolism, or a combination thereof..
Stealth Bio Therapeutics Corp


06/09/16
20160164964 

Optimized consistent request distribution for balanced load distribution in a content delivery network


Some embodiments provide a proprietary 64-bit consistent distribution scheme that preserves the efficiencies of carp while providing a significantly more balanced distribution of requests that is on par with schemes reliant on computationally expensive cryptographic hashes. The scheme performs hashing of requested urls and identifiers of available servers over a 64-bit space while optimizing the hashing to remove computationally expensive operations.
Edgecast Networks, Inc.


06/09/16
20160163676 

Single layer low cost wafer level packaging for sff sip


In one embodiment of the invention, a system in package (sip) is described which includes a plurality of device components with different form factors embedded within a molding compound layer. A surface for each of the device components is coplanar with a surface of the molding compound layer, and a single redistribution layer (rdl) formed on the coplanar surfaces of the molding compound layer and the plurality of device components.
Intel Corporation


06/09/16
20160163342 

Apparatus, systems and processes for reducing a hard disk drive's access time and concomitant power optimization


Rotational latency is reduced in a standard conventional form factor hdd system by replacing, for example, the prior art rotary arm actuator of a conventional hdd, with one or more belts and pulleys and one or more read/write heads mounted on, or otherwise associated with the belts. Multiple scaled iterations facilitate energy savings and power optimized systems, without compromise to data access performance..
L2 Drive Llc


06/09/16
20160162911 

End-to-end effective citizen engagement via advanced analytics and sensor-based personal assistant capability (eeceaspa)


Providing an end-to-end citizen engagement, in one aspect, may comprise obtaining data of multiple disintegrated sources from one or more of communication and social computing channels via one or more adapters. Data refactoring and management, integration and process orchestration of the data according to a data model as data attributes of the data model may be provided.
International Business Machines Corporation


06/09/16
20160159929 

Novel dual-targeting protein binding specifically to dll4 and vegf and use thereof


The present invention relates to a novel dual-targeting protein comprising: a protein that binds specifically to delta-like ligand 4 (dll4); and an antibody that binds specifically to vascular endothelial cell growth factor (vegf).. .
Hanwha Chemical Corporation


06/09/16
20160159869 

Bmp-2-binding peptide amphiphile nanofibers


Provided herein are peptide amphiphiles with binding affinity for the bone promoting growth factor bmp-2, and methods of use thereof. In particular nanofibers and gel scaffolds of bmp-2-binding peptide amphiphiles are provided..
Northwestern University


06/09/16
20160158819 

Compact pneumatic auto body hammer with fine control of impact force


A hand-held pneumatic impact tool for striking and planishing metal panels includes a monostable, reciprocating impact mechanism in a small form factor, with an air pressure regulator to control striking force and interchangeable toolheads to apply the force as necessary to repair dented or crumpled vehicle bodies.. .

06/09/16
20160158358 

Antibodies for epidermal growth factor receptor 3 (her3)


This invention relates to antibodies or fragments thereof which interact with her family of receptors, e.g., her3 receptor. In particular, it relates to antibodies or fragments thereof that recognize a conformational epitope of her3 receptor comprising residues from both domains 2 and 4 resulting in inhibition of both ligand-dependent and ligand-independent signal transduction; and allow ligand binding (e.g., neuregulin), whilst preventing ligand-induced activation of signal transduction.
Novartis Ag


06/09/16
20160158319 

Remodeling and glycopegylation of fibroblast growth factor (fgf)


The present invention relates to mutants of fibroblast growth factor (fgf), particularly fgf-20 and fgf-21, which contain newly introduced n-linked or o-linked glycosylation site(s). The polynucleotide coding sequences for the mutants, expression cassettes comprising the coding sequences, cells expressing the mutants, and methods for producing the mutants are also disclosed.
Novo Nordisk A/s


06/09/16
20160158292 

Method and recovery of umbilical cord tissue derived regenerative cells and uses thereof


Methods for the extraction and processing of umbilical stem cells for therapeutic and diagnostic purposes are disclosed. The methods provide high regenerative cell numbers and high cell viability.
Ingeneron, Inc.


06/09/16
20160158235 

Biological markers predictive of anti-cancer response to epidermal growth factor receptor kinase inhibitors


The present invention provides diagnostic and prognostic methods for predicting the effectiveness of treatment of a cancer patient with an egfr kinase inhibitor. Methods are provided for predicting the sensitivity of tumor cell growth to inhibition by an egfr kinase inhibitor, comprising assessing whether the tumor cell has undergone an epithelial to mesenchymal transition (emt), by determining the expression level of epithelial and/or mesenchymal biomarkers, wherein tumor cells that have undergone an emt are substantially less sensitive to inhibition by egfr kinase inhibitors.
Osi Pharmaceuticals, Llc


06/09/16
20160157870 

Methods and devices to reduce the likelihood of injury from concussive or blast forces


A method and device for reducing the damaging effects of radiant energy, blast, or concussive events includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during or before the incidence of the imparting event. Reducing blood outflow from the cranial cavity increases intracranial volume and/or pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column.
Thornhill Research, Inc.


06/02/16
20160156720 

Personally-wearable internet of things microcontrolled device


An internet of things device containing a memory device, gps antenna, wi-fi connection, microcontroller and power source that is in a mobile, compact, flexible form factor. System units can execute specific functionality it is programmed and can be easily reprogrammed by a user.
Warcollar Industries, Llc


06/02/16
20160156655 

System and methods for malware detection using log analytics for channels and super channels


Log based analysis systems and methods for protecting computers and networks from malicious communications and malware attacks by analyzing log data obtained from client networks having network entities representing business units or customers. The system may further comprise a plurality of client asset machines, each operable to execute a security product associated with a security product vendor and log associated information of the network entities into at least one log file.
Seculert Ltd.


06/02/16
20160156047 

Fuel cell system


A fuel cell system (10) with a toggle switch (32) between an on or off position is provided. In the off position, gas is purged from the fuel cell.
Intelligent Energy Limited


06/02/16
20160155765 

Image sensor with tolerance optimizing interconnects


Embodiments of a hybrid imaging sensor that optimizes a pixel array area on a substrate using a stacking scheme for placement of related circuitry with minimal vertical interconnects between stacked substrates and associated features are disclosed. Embodiments of maximized pixel array size/die size (area optimization) are disclosed, and an optimized imaging sensor providing improved image quality, improved functionality, and improved form factors for specific applications common to the industry of digital imaging are also disclosed.
Olive Medical Corporation


06/02/16
20160155126 

Method for implementing and integrating biometric markers, identification, real-time transaction monitoring with fraud detection and anti-money laundering predictive modeling systems


A method for implementing and integrating biometrical markers, identification, real-time transaction monitoring with fraud detection and anti-money laundering predictive modeling systems as the means of identifying, measuring, detecting and reporting the importance assigned to each member of a population of transactions coupled with images of participants whereby a relationship exists, or groups of relationships, by and between the transactions and the persons identified in the images and/or being affected by at least one suspicious activity factor, transaction or pattern. According to the method, an image is captured and attached to a financial transaction.

06/02/16
20160154765 

Storage node based on pci express interface


A storage node includes a storage element module. The module includes a first peripheral component interconnect express (pcie) switch suitable for uplink connection, a second pcie switch coupled to the first pcie switch, and at least one connection element coupled to the second pcie switch, suitable for coupling with at least one storage element.
Sk Hynix Memory Solutions Inc.


06/02/16
20160154762 

Eletronic device and electronic device assembly


An electronic device includes a system bus, an enhanced serial peripheral interface (e-spi) bus, and a next generation form factor (ngff) socket. The ngff socket includes a plurality of functional pins and a plurality of pins which are reversed.
Hon Hai Precision Industry Co., Ltd.


06/02/16
20160154402 

Production performance management device and production performance management method thereof


A production performance management device and a production performance management method thereof are provided. The production performance management device includes a connection interface, a storage and a processor.
Institute For Information Industry


06/02/16
20160153884 

System and conducting particle monitoring using low cost particle sensors


There is disclosed a field calibratable particle sensor solution in a low-cost, very compact form factor. This makes a low-cost sensor more accurate for low-concentration pollution measurements and decreases the cost of pollution measurement systems having a wide geographic coverage.
Tsi, Incorporated


06/02/16
20160152965 

Transgenic factor vii having a specific n-glycosylation and substantially homogenous isoelectric point


The present invention relates to a factor vii composition having a substantially homogeneous isoelectric point and to a method for formulating such a composition. The present invention also relates to the therapeutic use of a factor vii composition having a substantially homogeneous isoelectric point..
Laboratoire Francais Du Fractionnement Et Des Biotechnologies


06/02/16
20160152710 

Milk fat globule epidermal growth factor 8 regulates fatty acid uptake


Methods and compositions for regulating fatty acid uptake and/or decreasing gastric motility in an animal are provided. The method comprises administering an antagonist of integrin αvβ3 or αvβ5 to an animal in an amount sufficient to reduce fatty acid uptake in the animal, thereby reducing fatty acid uptake in the animal.
Regents Of The University Of California


06/02/16
20160152688 

Targeted therapeutics based on engineered proteins that bind egfr


The present invention relates to single domain proteins that bind to epidermal growth factor receptor (egfr). The invention also relates to single domain proteins for use in diagnostic, research and therapeutic applications.
Bristol-myers Squibb Company


06/02/16
20160152613 

Substituted oxopyridine derivatives and use thereof as factor xia/plasma


The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.. .
Bayer Pharma Aktiengesellschaft


06/02/16
20160151537 

Bioactive grafts and composites


Disclosed are various bioactive grafts and methods of making the same. In one embodiment, bone material is harvested from a donor.
Bioventus Llc


05/26/16
20160149235 

Modular fuel cell and fuel source


A fuel cell power module is coupled to a fuel supply reactor module by way of an adaptor which includes some of the control elements for controlling reaction of reactants in the reactor module. The adaptor includes a housing and a first connection interface in the housing for detachably coupling the adaptor to a fuel cell power module fuel inlet port and a second connection interface in the housing for detachably coupling the adaptor to a reactor module fuel outlet port.
Intelligent Energy Limited


05/26/16
20160148321 

Simplified screening for predicting errors in tax returns


Embodiments of the invention generally relate to predicting the likelihood of an error in a previously filed tax return. In particular, a set of screening questions is presented to a user that correlate to set of risk factors for an erroneous return.
Hrb Innovations, Inc.


05/26/16
20160147688 

Method and plug and play, networkable iso 18000-7 connectivity


A device may comprise a universal serial bus (usb) interface and a wireless interface operable to communicate in accordance with the iso 18000-7 standard. The device may be operable to receive a command via the usb interface and transmit the command via the wireless interface.
Blackbird Technology Holdings, Inc.


05/26/16
20160146784 

Compositions and methods of screening for compounds that modulate activity at a tweak binding site on a crd of fn14


The present disclosure is directed to methods of screening a compound for modulating activity at a tnf-like weak inducer of apoptosis (tweak) binding site on a cysteine-rich domain (crd) of fibroblast growth factor-inducible 14 (fn14). The present disclosure also provides heterocyclic compounds and pharmaceutically acceptable salts thereof and methods for the prevention, treatment, and amelioration of cell proliferative disorders with these compounds..
The Translational Genomics Research Institute


05/26/16
20160146783 

Compositions and methods for treating cancer and diseases and conditions responsive to cell growth inhibition


In alternative embodiments, the invention provides compositions and methods for overcoming or diminishing or preventing growth factor inhibitor resistance in a cell, or, a method for increasing the growth-inhibiting effectiveness of a growth factor inhibitor on a cell, or, a method for re-sensitizing a cell to a growth factor inhibitor, comprising for example, administration of a combination of a tbk1 inhibitor and an rtk inhibitor. In alternative embodiments, the cell is a tumor cell, a cancer cell or a dysfunctional cell.
The Regents Of The University Of California


05/26/16
20160145598 

Factor x mutants


Mutation c′ consists of inserting a sequence chosen from tskltr, fndftr, lssmtr, ppsltr and lscgqr, between amino acids 52 and 53 of sequence seq id no. 1, and of deleting amino acids 4 to 9 from sequence seq id no.

05/26/16
20160145577 

Human multipotent embryonic stem cell-like progenitor cells


The invention provides a plurality of embryonic stem cell-like progenitor cells, which are isolated from a human tissue by a systemic screening of human mesenchymal stromal stem/progenitor cells and a cell sorting by a cell antigen selected from the group consisting of cd34, cd117, cd133, cd201, globoh and combination thereof, and cultured in a medium supplemented with at least one or more steroids and one or more growth factors. The cells of the invention express cd34 and exhibit sphere-like clonogenicity in early passages and express multipotent embryonic stem cells (escs) like characteristics..
Sunshine Life Science & Technology Corp.


05/26/16
20160145342 

Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof


Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible tnf receptor (gitr). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer.
Bristol-myers Squibb Company


05/26/16
20160145263 

Tetrahydroisoquinolines containing substituted azoles as factor xia inhibitors


The present invention provides compounds of formula (i), or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor xia inhibitors or dual inhibitors of fxia and plasma kallikrein.
Bristol-myers Squibb Company


05/26/16
20160145251 

Inhibitors of myocardin-related transcription factor and serum response factor (mrtf/srf)-mediated gene transcription and methods for use of the same


Wherein the substituents are as described.. .

05/26/16
20160145237 

Protein tyrosine kinase modulators and methods of use


Heterocyclic pyrimidine compounds that modulate mutant-selective epidermal growth factor receptor (egfr) and alk kinase activity are disclosed. More specifically, the invention provides pyrimidines which inhibit, regulate and/or modulate kinase receptor, particularly in selectively modulation of various egfr mutant activity and alk kinase activity have been disclosed.
Betta Pharmaceuticals Co., Ltd






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