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Expression Vector

Expression Vector-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Fc containing polypeptides with altered glycosylation and reduced effector function
Genzyme Corporation
April 12, 2018 - N°20180100010

Provided are binding polypeptides (e. G., antibodies), and drug conjugates thereof, comprising an fc domain with an altered glycosylation profile and reduced effector function. In particular embodiment, the fc domain comprises: an asparagine residue at amino acid position 298, according to eu numbering; and a serine or threonine residue at amino acid position 300, according to eu numbering. Also provided are nucleic ...
Eukaryotic expression vectors comprising regulatory elements of the globin gene clusters
Glycotope Gmbh
April 05, 2018 - N°20180094279

The present invention pertains to the field of recombinant protein production. Novel expression cassettes comprising elements of the human globin gene clusters are provided which show enhanced expression rates of proteins or polypeptides of interest.
Novel insecticidal proteins and methods of use
Pioneer Hi-bred International, Inc.
April 05, 2018 - N°20180094278

Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are isolated insecticidal proteins and nucleic acids. The ...
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Expression Vector Patent Applications
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  • 166+ full patent PDF documents of Expression Vector-related inventions.
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Bgl7 beta-glucosidase and nucleic acids encoding the same
Danisco Us Inc.
March 29, 2018 - N°20180087037

The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl7, and the corresponding bgl7 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding bgl7, recombinant bgl7 proteins and methods for producing the same.
Anti-cd303 monoclonal antibodies
Laboratoire Francais Du Fractionnement Et Des Biotechnologies
March 29, 2018 - N°20180086834

The invention relates to chimeric or humanised anti-cd303 antibodies to nucleic acids coding for the heavy and light chains of these antibodies, expression vectors, host cells, transgenic non-human animals or transgenic plants expressing said antibodies, as well as to the uses thereof in the treatment or prevention of blastic plasmacytoid dendritic cell neoplasms (bpdcn) or inflammatory diseases, in particular autoimmune ...
Mirna mimetics and their use in treating sensory conditions
Miragen Therapeutics, Inc.
March 22, 2018 - N°20180080023

The present invention provides microrna mimetic compounds that mimic the function or activity of mir-96, mir-182, and/or mir-183. The microrna mimetic compounds of the invention comprise a first strand of about (22) to about (26) ribonucleotides comprising a mature mir-96, mir-182, or mir-183 sequence; and a second strand of about (20) to about (24) ribonucleotides comprising a sequence that is substantially complementary to ...
Expression Vector Patent Pack
Download 166+ patent application PDFs
Expression Vector Patent Applications
Download 166+ Expression Vector-related PDFs
For professional research & prior art discovery
inventor
  • 166+ full patent PDF documents of Expression Vector-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Novel expression regulating rna-molecules and uses thereof
Universität Wien
March 15, 2018 - N°20180073026

The present application relates to a rna molecule comprising a rna-polymerase binding aptamer, wherein said rna-polymerase binding aptamer has a length of 15 to 60 nt, wherein said rna-polymerase binding aptamer binds to a rna-polymerase with a kd of 50 nm or lower. Furthermore, the application discloses a dna molecule comprising a sequence encoding an rna-polymerase binding aptamer of the invention, and a ...
Expression vectors for an improved protein secretion
Basf Se
March 15, 2018 - N°20180073005

The aim of the invention is to improve the secretion of a protein from a host cell in order to increase the product yield of protein in a fermentation process. This is achieved by an expression vector comprising a) a promoter sequence and b) a nucleic acid sequence that codes for a protein. The protein comprises a signal peptide and ...
Generation of functional cells from stem cells
Agency For Science, Technology And Research
March 15, 2018 - N°20180072988

The present disclosure provides a method of directly converting a stem cell into a lineage specific cell, comprising the steps of a) transfecting a stem cell with at least one expression vector comprising i) one or more cell lineage reprogramming factors operably linked to an inducible promoter and ii) a selection marker; and b) inducing the transfected stem cell from ...
Cell line overexpressing human cd303 antigen
Laboratoire Francais Du Fractionnement Et Des Biotechnologies
March 08, 2018 - N°20180066060

The invention relates to a cell line expressing the gamma chain of the fcεri receptor and human cd303 antigen, characterised in that said cell line is transfected in a stable manner by an expression vector comprising a nucleic acid molecule coding for human cd303 antigen and having strong expression of human cd303 on the surface thereof, e. ...
Human antibodies that bind lymphocyte activation gene-3 (lag-3), and uses thereof
E. R. Squibb & Sons, L.l.c.
March 08, 2018 - N°20180066054

The present disclosure provides isolated monoclonal antibodies that specifically bind to lag-3 with high affinity, particularly human monoclonal antibodies. Preferably, the antibodies bind human lag-3. In certain embodiments, the antibodies bind both human and monkey lag-3 but do not bind mouse lag-3. The invention provides anti-lag-3 antibodies that can inhibit the binding of lag-3 to mhc class ii molecules and ...
Raav vector compositions, methods for targeting vascular endothelial cells and use in treatment of type ...
University Of Florida Research Foundation, Inc.
March 01, 2018 - N°20180057840

Disclosed are capsid-modified raav expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations that include them. Also disclosed are methods of preparing and using novel capsid-protein-mutated raav vector constructs in a variety of diagnostic and therapeutic applications including, inter alia, as delivery agents for diagnosis, treatment, or amelioration of one or more diseases, disorders, or dysfunctions of the ...
Expression vector
Fujifilm Diosynth Biotechnologies Uk Limited
March 01, 2018 - N°20180057823

An expression vector for expressing a target polypeptide in a prokaryotic cell is provided. The vector comprises a promoter operably linked to a polynucleotide encoding the target polypeptide operably linked to a eukaryotic secretion leader sequence, the eukaryotic secretion leader sequence encoding a signal peptide sequence selected from the group consisting of: a) mlkrsswlatlglltvasvstivya; b) mkkatfitcllavllvsnpiwna; c) mkvsaaalaviliatalcapasa; d) mkvstaflcllltvsafsaqvla; ...
Expression Vector Patent Pack
Download 166+ patent application PDFs
Expression Vector Patent Applications
Download 166+ Expression Vector-related PDFs
For professional research & prior art discovery
inventor
  • 166+ full patent PDF documents of Expression Vector-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
High-throughput drug and genetic assays for cellular transformation
Massachusetts Institute Of Technology
February 22, 2018 - N°20180051319

A method for detecting oncogenic growth and viability, and/or degree of cellular transformation and/or identifying an agent that inhibits cellular transformation is disclosed. The method including: providing a cellular sample, such as a sample of cells obtained from a subject or a cell line; culturing the cellular sample in low attachment conditions; and detecting growth and7or cell ...
Codon optimized il-15 and il-15r-alpha genes for expression in mammalian cells
February 15, 2018 - N°20180044392

The present invention further provides expression vectors, and il-15 and il-15 receptor alpha combinations (nucleic acid and protein) that increase il-15 stability and potency in vitro and in vivo. The present methods are useful for the increased bioavailability and biological effects of il-15 after dna, rna or protein administration in a subject (e. G. A mammal, a human).
Insecticidal combinations of pip-72 and methods of use
E. I. Du Pont De Nemours And Company
February 15, 2018 - N°20180042242

Compositions and methods for controlling pests are provided. The methods involve transforming organisms with one or more nucleic acid sequence encoding insecticidal protein(s) and one or more silencing element(s). In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. ...
Compositions and methods for transient delivery of nucleases
University Of Massachusetts
February 08, 2018 - N°20180037877

The disclosure in some aspects relates to recombinant adeno-associated viruses having nuclease grafted to one or more capsid proteins. In some aspects, the disclosure relates to isolated aav capsid proteins having terminally grafted nucleases and isolated nucleic acids encoding the same. Recent approaches to delivering nucleases to cells for gene editing have focused on delivering of expression vectors engineered to ...
Elimination of proliferating cells from stem cell-derived grafts
Research Development Foundation
February 01, 2018 - N°20180030478

Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.
Multiplex characterization of microbial traits using dual barcoded nucleic acid fragment expression library
The Regents Of The University Of California
February 01, 2018 - N°20180030435

Disclosed herein are barcoded expression libraries comprising a plurality of expression vectors, wherein each expression vector comprises a nucleic acid fragment flanked by a first barcode and a second barcode. Further disclosed herein are methods of making the barcoded expression libraries and methods of conducting functional analysis using the barcoded expression libraries.
Egvi endoglucanase and nucleic acids encoding the same
Danisco Us Inc.
February 01, 2018 - N°20180030426

The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding egvi amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding egvi, recombinant egvi proteins and methods for producing the same.
Plasmids and method for obtaining viral particles
Universidad De Santiago De Chile
February 01, 2018 - N°20180030416

The present invention describes a viral rna expression plasmid and a method for obtaining viral particles based on said plasmids comprising transfecting animal cells with an expression vector or a set of expression vectors capable of expressing a nucleoprotein and rna-dependent polymerase rna; and transfecting the animal cell with an expression vector or a set of expression vectors with nucleotide ...
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