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Erythropoietin topics
Erythropoietin
Red Blood Cell
Recombinant
Nucleic Acid
Genetically
Regulatory Sequence
Endogenous
Peptide Sequence
Carbamylated
Ischemic Stroke
Therapeutical
Intracranial
Thrombopoietin
Leukemia Inhibitory Factor
Somatostatin

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Erythropoietin patents



      
           
This page is updated frequently with new Erythropoietin-related patents. Subscribe to the Erythropoietin RSS feed to automatically get the update: related Erythropoietin RSS feeds.

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Date/App# patent app List of recent Erythropoietin-related patents
02/20/14
20140053288
 Epo knockout gfp anemic mouse patent thumbnailEpo knockout gfp anemic mouse
The present invention relates to a model animal spontaneously developing anemia. More specifically, the invention relates to a transgenic non-human mammal spontaneously developing anemia associated with a postnatal decrease in production of erythropoietin (epo), epo-producing cells prepared from the transgenic non-human mammal, and a screening method using the epo-producing cells..
02/13/14
20140045748
 Composition for aiding surgical procedures for treating ischemic vascular diseases patent thumbnailComposition for aiding surgical procedures for treating ischemic vascular diseases
The present invention relates to a composition comprising erythropoietin (epo) as an active ingredient for aiding surgical procedures for treating ischemic vascular diseases. The present invention also relates to a method for treating ischemic vascular diseases using said composition.
01/23/14
20140024699
 Compositions and methods for increasing erythropoietin (epo) production patent thumbnailCompositions and methods for increasing erythropoietin (epo) production
The invention relates to double-stranded ribonucleic acid (dsrna) compositions targeting one or more egln genes, egln1, egln2 and/or egln3 and methods of using such dsrna compositions to inhibit expression of these genes.. .
01/16/14
20140017305
 Encapsulated liver cell composition patent thumbnailEncapsulated liver cell composition
Microcapsules including a capsule shell encapsulating a suspension of a therapeutically effective amount of liver cells in physical contact with a liver cell stimulating amount of erythropoietin.. .
01/09/14
20140011740
 Modified animal erythropoietin polypeptides and their uses patent thumbnailModified animal erythropoietin polypeptides and their uses
Modified animal erythropoietin polypeptides and uses thereof are provided.. .
01/02/14
20140005109
 Therapeutic compositions and methods for disorders associated with neuronal degeneration patent thumbnailTherapeutic compositions and methods for disorders associated with neuronal degeneration
Disclosed are isolated mutant erythropoietin (epo) polypeptides, functional fragment thereof, nucleic acid encoding such peptides, vectors including such nucleic acids and compositions including such peptides and nucleic acids. The mutant epo peptides are unique in that they include a substitution at amino acid position number 76, such as a glutamic acid for arginine substitution at position 76.
12/26/13
20130345158
 Composition for promoting hematogenesis containing quercetin 3-o-beta-(2''-galloyl)-rhamnopyranoside as active ingredient patent thumbnailComposition for promoting hematogenesis containing quercetin 3-o-beta-(2''-galloyl)-rhamnopyranoside as active ingredient
This invention relates to a composition for promoting hematopoiesis and for treating, preventing or alleviating cytopenia or bone marrow failure comprising quercetin 3-o-β-(2″-galloyl)-rhamnopyranoside (qgr) as active ingredient. The present active compound qgr (i) increases dose dependently the mrna expression of cytokines involved in hematopoiesis including stem cell factor, granulocyte-macrophage colony stimulating factor and erythropoietin from mouse bone marrow mononuclear cells, (ii) promotes the formation of burst forming unit-erythroid and colony forming unit-fibroblast, (iii) stimulates the generation of cells positive for ter-119, a specific marker of mouse erythroid precursors, (iv) promotes erythropoiesis, leukopoiesis, thrombopoiesis, and hemoglobin production in bone marrow failure mouse model, (v) stimulates the formation of hematopoietic stem/progenitor cells and mesenchymal stem/progenitor cells, (vi) stimulates megakaryocyte formation surrounding the blood system of damaged bone marrow, osteoid formation and bone marrow restoration through a recovery of damaged bone marrow microenvironment.
12/26/13
20130344497
 Use of novel cytokine receptors as biomarkers and therapeutic targets in human cancer patent thumbnailUse of novel cytokine receptors as biomarkers and therapeutic targets in human cancer
Nucleic acids encoding erythropoietin isoforms are described herein, as well as the encoded isoforms, methods of detecting the same, and methods of screening for and treating cancer.. .
12/26/13
20130344032
 Method of treating anemia caused by ribavirin treatment of hepatitis c using erythropoietin alpha patent thumbnailMethod of treating anemia caused by ribavirin treatment of hepatitis c using erythropoietin alpha
Claimed and disclosed is a new use for a previously approved drug: erythropoietin. The present invention teaches using erythropoetin to treat anemia caused by the combined treatment of ribavirin and alpha-interferon.
12/05/13
20130323774
 Homogenous and fully glycosylated human erythropoietin patent thumbnailHomogenous and fully glycosylated human erythropoietin
The present invention provides homogenous, fully-glycosylated, full length erythropoietin and the methods of producing the same.. .
11/28/13
20130316967
Compounds and methods for enhancing erythropoiesis
Compounds and methods for enhancing erythropoiesis. The compound contains a chemical structure of the formula (i) indicated below, in which r is a glucosyl group.
11/21/13
20130310565
Novel nitrogen-containing heteroaryl compounds and methods of use thereof
The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo.. .
11/07/13
20130295113
Anti-erythropoietin antibodies
The present disclosure provides compositions and methods relating to antibodies that specifically bind to human erythropoietin. The disclosure provides nucleic acids encoding such antibodies and methods of making and using such antibodies..
10/03/13
20130259853
Treatment of acute ischemic stroke or intracranial bleeding with tpa and carbamylated erythropoietin
The present invention relates a method for the treatment of intracranial bleeding comprising administration of a therapeutically effective amount of tpa and a therapeutically effective amount of carbamylated erythropoietin.. .
09/26/13
20130251679
Long lasting drug formulations
The present invention is directed to long-lasting erythropoietin therapeutic formulations and their methods of use wherein the formulation comprises a genetically modified micro-organ that comprises a vector which comprises a nucleic acid sequence operably linked to one or more regulatory sequences, wherein the nucleic acid sequence encodes erythropoietin.. .
09/19/13
20130244939
Novel peptides that bind to the erythropoietin receptor
The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (epo-r). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production.
09/12/13
20130236432
Method and device for multiplying and differentiating cells in the presence of growth factors and of a biological matrix or of a supporting structure
The invention relates to an in-vitro and in-vivo method for multiplying and differentiating cells, during which the growth process of the cells is initiated or terminated and structurally directed by the use of growth factors thrombopoietin (tpo) and/or erythropoietin (epo), and/or growth hormone (gh), particularly human growth hormone (hgh), and/or somatostatin and/or leukemia inhibitory factor (lif) and/or ciliary neurotropic factor (cntf). The invention also relates to a biological matrix or supporting structure containing the aforementioned growth factors, and to a method and device for the production thereof and for carrying out the inventive method..
08/29/13
20130224198
Recombinant human epo-fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo
A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has a prolonged half-life in vivo compared to naturally occurring or recombinant native human erythropoietin.
08/08/13
20130203805
Methods for treating anemia using inhibitors of hypoxia-inducible factor (hif) hydroxylase
The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included.
08/01/13
20130196907
Promoting erythropoietin, erythrocyte, and hematopoietic stem cell production by activating hif in osteoblasts
Methods are provided for promoting the production of erythropoietin and the production of erythrocytes and hematopoietic stem and progenitor cells. These methods find us in the treatment of subjects with conditions in which erythrocyte cell numbers are reduced, for example, anemia, chronic kidney disease, and following chemotherapy treatment..
07/11/13
20130178417
Novel nitrogen-containing heteroaryl compounds and methods of use thereof
The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo.. .
07/04/13
20130171107
Long lasting drug formulations
The present invention is directed to long-lasting therapeutic formulations and their methods of use wherein the formulation comprises a genetically modified micro-organ that comprises a vector which comprises a nucleic acid sequence operably linked to one or more regulatory sequences, wherein the nucleic acid sequence encodes a therapeutic polypeptide, such as erythropoietin or interferon alpha.. .
06/13/13
20130149347
Isolated renal cells and uses thereof
The invention is directed to isolated renal cells, including tubular and erythropoietin (epo)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.. .
05/23/13
20130130979
Peptides that bind to the erythropoietin receptor
The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (epo-r). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production.
05/16/13
20130123174
Neuritogenic peptides
The present invention relates to peptide compounds that are capable of stimulating neuronal differentiation, neurite outgrowth and survival of neural cells, and enhancing synaptic plasticity, learning and memory, methods of treating diseases and conditions of nervous system by administration of compositions comprising said compounds. The compounds and compositions of the invention include peptide sequences that are derived from the sequence of human erythropoietin or proteins that are homologous of human erythropoietin..
05/09/13
20130116176
Derivatisation of erythropoietin (epo)
The present invention relates to a compound which is a polysaccharide derivative of epo, or of an epo like protein, wherein the polysaccharide is anionic and comprises between 2 and 200 saccharide units. The present invention also relates to pharmaceutical compositions comprising the novel compounds, and methods for making the novel compounds..
04/25/13
20130102530
Protection, restoration and enhancement of erythropoietin-responsive cells, tissues and organs
Methods and compositions are provided for protecting or enhancing an erythropoietin-responsive cell, tissue, organ or body part function or viability in vivo, in situ or ex vivo in mammals, including human beings, by systemic or local administration of an erythropoietin receptor activity modulator, such as an erythropoietin or a modified erythropoietin.. .
04/18/13
20130096155
Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor or erythropoietin production-inducing agent
Wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof, or a solvate thereof, as well as a prolyl hydroxylase inhibitor or erythropoietin production-inducing agent containing the compound. The compound of the present invention shows a prolyl hydroxylase inhibitory action and an erythropoietin production-inducing ability and is useful as a prophylactic or therapeutic agent for various diseases and pathologies (disorders) caused by decreased production of erythropoietin..
03/28/13
20130079283
Erythropoitein receptor peptide formulations and uses
The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (epo-r). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production.
03/21/13
20130071393
Methods for increasing red blood cell levels and treating anemia using a combination of gdf traps and erythropoietin receptor activators
In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.. .
01/17/13
20130017995
Modified animal erythropoietin polypeptides and their uses
Modified animal erythropoietin polypeptides and uses thereof are provide.. .
01/10/13
20130012685
Novel peptides that bind to the erythropoietin receptor
The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (epo-r). The invention further relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production.


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Erythropoietin topics: Erythropoietin, Red Blood Cell, Recombinant, Nucleic Acid, Genetically, Regulatory Sequence, Endogenous, Peptide Sequence, Carbamylated, Ischemic Stroke, Therapeutical, Intracranial, Thrombopoietin, Leukemia Inhibitory Factor, Somatostatin

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