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Enzyme patents



      
           
This page is updated frequently with new Enzyme-related patent applications. Subscribe to the Enzyme RSS feed to automatically get the update: related Enzyme RSS feeds. RSS updates for this page: Enzyme RSS RSS


Date/App# patent app List of recent Enzyme-related patents
07/17/14
20140200201
 Enzymatic production or chemical synthesis and uses for 5,7-dienes and uvb conversion products thereof patent thumbnailnew patent Enzymatic production or chemical synthesis and uses for 5,7-dienes and uvb conversion products thereof
Provided herein are steroidal compounds that are androsta-5,7-dienes or a pregna-5,7-dienes and ultraviolet b (uvb) conversion products thereof which includes pharmaceutical compositions of the steroidal compounds as shown in tables 1 and 2. Also provided is a method for producing hydroxylated metabolites of cholecalciferol or ergocalciferol via the p450scc (cyp11a1) or cyp27b1 enzyme systems where the hydroxylase has an activity to hydroxylate position c20 of a secosteroid or its 5,7-dieneal precursor and the hydroxylated metabolites so produced.
07/17/14
20140199752
 Reduction of culture viscosity by manganese addition patent thumbnailnew patent Reduction of culture viscosity by manganese addition
A method of producing an enzyme of interest in a fed-batch cultivation comprising: a) cultivating a microorganism in a culture medium conducive to its growth wherein the microorganism produces the enzyme of interest; and b) adding a manganese compound to the culture medium one or more times during the cultivation.. .
07/17/14
20140199738
 Method for preparing volatile fatty acids from the pre-treated extracts of marine biomass residue patent thumbnailnew patent Method for preparing volatile fatty acids from the pre-treated extracts of marine biomass residue
A method of preparing a volatile fatty acids (vfas) is provided. More particularly, the method includes chemically or biologically pretreating a residue of algae to obtain an extract of the algae residue, filtering the extract of the algae residue and anaerobically fermenting the filtrate.
07/17/14
20140199737
 Methods of producing 6-carbon chemicals via methyl-ester shielded carbon chain elongation patent thumbnailnew patent Methods of producing 6-carbon chemicals via methyl-ester shielded carbon chain elongation
This document describes biochemical pathways for producing adipic acid, 6-aminohexanoic acid, 6-hydroxhexanoic acid, hexamethylenediamine, caprolactam, or 1,6-hexanediol by forming one or two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a c6 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the enzymes or homologs accepting methyl ester shielded dicarboxylic acid substrates..
07/17/14
20140199705
 Glucanases, nucleic acids encoding them and methods for making and using them patent thumbnailnew patent Glucanases, nucleic acids encoding them and methods for making and using them
The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-d-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-d-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-d-glucans or xyloglucans and other plant material containing cellulosic parts.
07/17/14
20140199690
 Materials and methods for high-throughput determination of genome-wide dna methylation profile patent thumbnailnew patent Materials and methods for high-throughput determination of genome-wide dna methylation profile
The present invention provides materials and methods for rapid and sensitive determination of global methylation profile of genomic dna. In one embodiment, the present invention provides the fluorescence polarization (fp) based measurement of dna methylation (fpdm) assay, wherein the fpdm assay comprises restriction digestion of dna molecules using a pair of methyl-sensitive and methyl-insensitive restriction endonuclease enzymes, polymerase chain extension of digested dna molecules via the incorporation of fluorescently labeled dntp(s), and analysis via fluorescence polarization techniques..
07/17/14
20140199603
 Biological fuel cell and methods patent thumbnailnew patent Biological fuel cell and methods
A fuel cell has an anode and a cathode with anode enzyme disposed on the anode and cathode enzyme is disposed on the cathode. The anode is configured and arranged to electrooxidize an anode reductant in the presence of the anode enzyme.
07/17/14
20140199412
 Treating inflammation with a binding system patent thumbnailnew patent Treating inflammation with a binding system
The teachings provided herein generally relate to site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites. More particularly, the systems taught here include a phenolic compound bound to a reactive oxygen species, wherein the phenolic compound and the reactive oxygen species react at a target area in the presence of an oxidoreductase enzyme..
07/17/14
20140199285
 Purine nucleoside phosphorylase as enzymatic activator of nucleoside prodrugs patent thumbnailnew patent Purine nucleoside phosphorylase as enzymatic activator of nucleoside prodrugs
A process for inhibiting a mammalian cancerous cell or virally infected cell includes providing a trichomonas vaginalis purine nucleoside phosphorylase enzyme or a tail mutant purine nucleoside phosphorylase enzyme in proximity to the mammalian cancerous cell or the virally infected cell and exposing the enzyme to a purine nucleoside phosphorylase enzyme cleavable substrate to yield a cytotoxic purine analog. The process includes introducing to the cell a vector containing the phosphorylase enzyme, or a dna sequence coding for the same and delivering to the cell an effective amount of the substrate such as 9-(β-d-arabinofuranosyl)-2-fluoroadenine (f-araa)..
07/17/14
20140197100
 Methods and compositions for reducing bisphenol a release patent thumbnailnew patent Methods and compositions for reducing bisphenol a release
Disclosed are methods, compositions and systems pertaining to polymer coatings that entrap enzymes, specifically enzymes capable of reducing carboxylic acids.. .
07/17/14
20140197042
new patent Saliva glucose monitoring system
A glucose sensor suitable for measuring glucose levels in human saliva is provided. Systems containing the glucose sensor and methods for making and using the sensor are also provided.
07/17/14
20140196631
new patent Visual assays for coatings incorporating bioactive enzymes for catalytic functions
Disclosed herein are materials such as a coating, comprising a lipolytic enzyme or organophosphrous compound degrading enzyme. Also disclosed herein are methods of visually detecting enzyme activity in a coating by contacting the coating with a substrate of an enzyme and a visual indicator that changes appearance upon production of a product of enzyme activity on a tack-free coating surface..
07/10/14
20140196169
Methods and means to modify a plant genome
Methods and means are provided to modify in a targeted manner the genome of a plant in close proximity to an existing elite event using a double stranded dna break inducing enzyme. Also provided are plants, in particular cotton plants showing tolerance to a field dose of at least 1× of at least one hppd inhibitor, and methods for making such plants..
07/10/14
20140194299
Compositions, methods and related uses for cleaving modified dna
Compositions, methods and related uses are provided relating to cleaving modified dna. For example, a set of dna fragments obtainable by enzymatic cleavage of a large dna is described where at least 50% are similarly sized and have a centrally positioned modified nucleotide.
07/10/14
20140193917
Modulation of meiotic recombination
The invention provides methods of modifying the level of expression or functional activity of factors such as enzymes or other catalytic proteins or structural proteins, alone or in concert, to modify the frequency of meiotic homologous recombination involving the exchange of genetic information between non-sister chromatids from homologous maternal and paternal chromosomes. The steps at which modulation may occur include: homologous chromosome pairing, double-strand break formation; resection; strand invasion; branch migration; and resolution.
07/10/14
20140193916
Electrotransformation of clostridium pasteurianum
By this invention, for the first time, a method for high-efficiency genetic transformation of the anaerobic bacterium clostridium pasteurianum is provided. Clostridium pasteurianum is a bacterium of substantial industrial importance, due to its selectivity and high productivity of the biofuel and biochemical n-butanol, and its ability to grow on a wide variety of inexpensive substrates.
07/10/14
20140193890
Thermostable enzymes and methods of making and using the same
Provided herein are compositions and methods for enhancing enzyme activity, half-life and/or thermostability. Also provided herein are compositions and methods including the enhanced enzymes.
07/10/14
20140193889
Enzymatic antimicrobial and antifouling coatings and polymeric materials
Disclosed herein are a coating, a textile finish, a wax, elastomer, a filler, an adhesive, or a sealant, as well as polymeric materials such as a plastic, a laminate, a composite, that includes an enzyme that degrades cell wall or cell membrane components (e.g., a lysozyme, lytic transglycosylase) alone or in combination with other enzymes such as a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme, or an antimicrobial peptide. Also disclosed herein are methods of retarding or preventing microbial growth on or in a coating, paint, textile finish, wax, elastomer, adhesive, sealant, filler, or a polymeric material, where such a surface material includes an enzyme that degrades cell wall or cell membrane components (e.g., a lysozyme, lytic transglycosylase)..
07/10/14
20140193888
Fabric and home care products
This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness.
07/10/14
20140193887
Use of secondary paraffin sulfonates for increasing the cleaning capacity of enzymes
An improvement for boosting the cleaning capacity of one or more enzymes includes providing one or more secondary paraffin-sulfonates to a cleaning composition. The method is particularly effective for textiles at low washing temperatures..
07/10/14
20140193879
Dfpase enzymes from aplysia californica
The present invention relates to isolated polypeptides having organophosphorous hydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
07/10/14
20140193873
Method for preparing a hydrocarbon
A method for preparing a hydrocarbon comprising contacting a fatty acid substrate with at least one fatty acid reductase and at least one fatty aldehyde synthetase and at least one fatty acyl transferase, wherein the fatty acid substrate is a fatty acid, a fatty acyl-acp, or a fatty acyl-coa or a mixture of any of these, to obtain a fatty aldehyde; and contacting the fatty aldehyde with at least one aldehyde decarbonylase enzyme.. .
07/10/14
20140193869
Cell-free system for converting methane into fuel and chemical compounds
The present disclosure relates, in some aspects, to cell-free methods and systems for large-scale conversion of methane to isobutanol, comprising combining, in a bioreactor at elevated pressure, methane, oxygen, and cell lysates containing methane monooxygenase, methanol dehydrogenase, and enzymes that catalyze the conversion of formaldehyde to isobutanol, to form a cell-free reaction mixture, and incubating under suitable conditions the cell-free reaction to convert methane to isobutanol.. .
07/10/14
20140193863
Methods of producing 7-carbon chemicals via c1 carbon chain elongation associated with coenzyme b synthesis
This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming one or two terminal functional groups, each comprised of carboxyl, amine or hydroxyl group, in a c7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the c1 elongation enzymes or homolog associated with coenzyme b biosynthesis..
07/10/14
20140193862
Methods of producing 7-carbon chemicals via carbon chain elongation associated with cyclohexane carboxylate synthesis
This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a c7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the carbon chain elongation enzymes or homologs thereof associated with the cyclohexane carboxylate biosynthesis from syntrophus aciditrophicus or 2-aminoadipate lysine biosynthesis..
07/10/14
20140193861
Methods of producing 7-carbon chemicals via aromatic compounds
This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoate, 7-hydroxyheptanoate, heptamethylenediamine, or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a c7 aliphatic backbone substrate produced from chorismate or benzoate. These pathways, metabolic engineering and cultivation strategies described herein rely on the anaerobic benzoyl-coa degradation pathway enzymes..
07/10/14
20140193830
Optical biosensors
Provided are biosensors, compositions comprising biosensors, and methods of using biosensors in living cells and organisms. The biosensors are able to be selectively targeted to certain regions or structures within a cell.
07/10/14
20140193801
Schiff-base conjugate of n, n-dibutyl-p-phenylenediamine with pyridoxal 5'-phosphate for improved homocysteine assays using pyridoxal 5'-phosphate-dependent enzymes
A composition, method and kit for performing a two-reagent enzymatic homocysteine assay, wherein a single homocysteinase enzyme and a schiff-based conjugate of n,n-dibutyl-p-phenyldiamine (dbpda) with pyridoxal 5′-phosphate (plp) are used to measure total homocysteine in plasma or serum. The assay measures a chromophore reaction product of h2s and the dbpda released from the schiff-base conjugate in the presence of a fe+3 containing compound.
07/10/14
20140193391
Method and compositions for improving selective catabolysis and viability in cells of keratin surfaces
A composition for treating keratin surfaces to stimulate selective catabolysis and improve cellular viability comprising at least one autophagy activator and at least one dna repair enzyme, and a method for improving selective catabolysis and cellular viability by treating with the composition.. .
07/10/14
20140193390
High concentration alpha-glucosidase compositions for the treatment of pompe disease
The present application provides for compositions comprising high concentrations of acid α-glucosidase in combination with an active site-specific chaperone for the acid α-glucosidase, and methods for treating pompe disease in a subject in need thereof, that includes a method of administering to the subject such compositions. The present application also provides methods for increasing the in vitro and in vivo stability of an acid α-glucosidase enzyme formulation..
07/10/14
20140193389
Method for treating oncological diseases
A method to treat cancer and other malignant diseases, said method comprising parenterally administering an agent which destroys blood extracellular dna into the systemic circulation of a cancer patient to slow down cancer growth. The agent is embodied in the form of a dnase enzyme and, more particularly, as a dnase i enzyme.
07/10/14
20140193387
Methods of reducing extravasation of inflammatory cells
A method for modifying access of cells to extravascular spaces and regions comprising administering to a patient an enzyme that cleaves chondroitin sulfate proteoglycans is provided. It has been found that administration of an enzyme that cleaves chondroitin sulfate proteoglycans to a patient disrupts extravasation of cells from the blood stream into tissue.
07/10/14
20140193386
Method for enzymatic cross-linking of a protein
A method for cross-linking albumin for use as a sealant or glue for a biological system, for example to induce hemostasis and/or prevent leakage of any other fluid from a biological tube or tissue, such as lymph for example. The cross-linked albumin may optionally and preferably be applied as part of a bandage for example.
07/10/14
20140193368
Pluripotent therapeutic compositions and uses thereof
Synthetic stem cell-like tissue healing and regeneration medication with anti-inflammatory, protein synthesis, enzyme deficiency activation and genetic therapy, and anti-cancer agent derived from a series of inventions that include these products of biomolecular engineering, drug discovery from a biologic periodic table of applied biochemistry and biophysics. Tissue has a self healing effect promoting tissue healing and tissue regeneration.
07/10/14
20140193342
Enzyme directed assembly of particle theranostics
Provided herein is a method for enzymatically triggered assembly of polymeric nanostructures for detection of cancer-associated enzymes in vivo. By detecting enzymatic signals associated with disease, one can sensitively determine the site, and extent of disease within a patient..
07/10/14
20140190526
Methods of using enzyme compositions
The present disclosure relates to compositions and methods for cleaning medical and dental instruments. The disclosed compositions are preferably non-foaming or generate low foam to allow visual inspection of the cleaning process as well as safe handling of the instruments.
07/10/14
20140190498
Nicotiana nucleic acid molecules and uses thereof
The present invention features nicotiana nucleic acid sequences such as sequences encoding constitutive, or ethylene or senescence induced polypeptides, in particular cytochrome p450 enzymes, in nicotiana plants and methods for using these nucleic acid sequences and plants to alter desirable traits, for example by using breeding protocols.. .
07/03/14
20140187553
Azole compounds as pim inhibitors
The invention relates to bicyclic compounds of formulas i and ia, and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of pim-1 and/or pim-2, and/or pim-3 protein kinase activity or enzyme function.
07/03/14
20140187468
Compositions and methods comprising a lipolytic enzyme variant
The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property.
07/03/14
20140186930
Methods for the improvement of product yield and production in a microorganism through the addition of alternate electron acceptors
The present invention provides for novel metabolic pathways to reduce or eliminate glycerol production and increase product formation. More specifically, the invention provides for a recombinant microorganism comprising a deletion of one or more native enzymes that function to produce glycerol and/or regulate glycerol synthesis and one or more native and/or heterologous enzymes that function in one or more engineered metabolic pathways to convert a carbohydrate source, such as lignocellulose, to a product, such as ethanol, wherein the one or more native and/or heterologous enzymes is activated, upregulated, or downregulated.
07/03/14
20140186925
Enzyme produced by arthrobacter globiformis
Task: there are provided a highly safe epimerase usable in food industry, and a method for producing a ketose. Resolution: the epimerase is a ketose 3-epimerase obtainable from a microorganism of the genus arthrobacter, and having (1) substrate specificity whereby a d- or l-ketose is epimerized at position 3 to produce a corresponding d- or l-ketose, and (2) the highest substrate specificity for d-fructose and d-psicose among d- and l-ketoses..
07/03/14
20140186924
Methods for transforming tarwi and for producing molecular farming products in transgenic tarwi seed
The present disclosure describes reproducible methods for the agrobacterium-mediated production of stable, genetically transformed, fertile tarwi plants (lupinus mutabilis sweet) having seed-specific expression of human adenosine deaminase enzyme (hada) or a functional variant thereof. The method involves slicing a tarwi seed embryo to produce an explant; infecting the explant in co-cultivation medium containing an agrobacterium having a polynucleotide sequence encoding hada or variant; thereby generating a transformed explant; elongating a transformed shoot from the transformed explant; and regenerating a transformed tarwi plant from the elongated shoot.
07/03/14
20140186919
Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
The invention provides for engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are compositions and methods related to components of a crispr complex particularly comprising a cas ortholog enzyme..
07/03/14
20140186918
Luciferase mutant
A recombinant protein having luciferase activity and at least 60% similarity to a wild-type luciferase wherein in the sequence of the enzyme, the amino acid residue corresponding to residue 357 in photinus pyralis luciferase is mutated as compared to the corresponding wild-type luciferase, such that the luciferase enzyme is able to emit light at a different wavelength as compared to the corresponding wild-type luciferase and/or has enhanced thermostability as compared to the corresponding wild-type luciferase. In general, the residue corresponding to 357 in photinus pyralis luciferase is changed from an acidic amino acid to a non-acidic amino acid, and preferably an uncharged polar amino acid such as tyrosine.
07/03/14
20140186913
Methods for biosynthesis of isobutene
The document provides methods for biosynthesizing isobutene using one or more isolated enzymes such as one or more of an enoyl-coa dehydratase, a 2-hydroxyacyl-coa dehydratase, an isovaleryl-coa/acyl-coa dehydrogenase and a mevalonate diphosphate decarboxylase, or using recombinant host cells expressing one or more such enzymes.. .
07/03/14
20140186912
Methods for improved ethanol production
Some embodiments provide a process for the production of ethanol. The process includes performing liquefaction, saccharification, and fermentation steps to produce ethanol from an organic material.
07/03/14
20140186910
Dhad variants for butanol production
Dihydroxy-acid dehydratase (dhad) variants that display increased dhad activity are disclosed. Such enzymes can result in increased production of compounds from dhad requiring biosynthetic pathways.
07/03/14
20140186904
Methods of producing 7-carbon chemicals via methyl-ester shielded carbon chain elongation
This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a c7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on enzymes or homologs accepting methyl ester shielded dicarboxylic acid substrates..
07/03/14
20140186902
Methods of producing 6-carbon chemicals via coa-dependent carbon chain elongation associated with carbon storage
This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, 6-hydroxyhexanoic acid, hexamethylenediamine or 1,6-hexanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a c6 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on coa-dependent elongation enzymes or analogues enzymes associated with the carbon storage pathways from polyhydroxyalkanoate accumulating bacteria..
07/03/14
20140186896
Use of glycoside hydrolase 61 family proteins in processing of cellulose
The invention provides recombinant gh61 proteins obtained from myceliophtora thermophila, and nucleic acids that encode such proteins. The invention also provides protein fractions isolated from m.
07/03/14
20140186880
Salmonella and/or e. coli enzyme test and/or liquid drop test for biological substances, on non-human samples
A test kit and test apparatus are provided for the detection of enzymes excreted by broken or ruptured bacteria cells in various environments, such as in the field, soil extracts, produce washing, slaughter houses, food preparation area's and other related or non-related areas where a quick test or rapid test is needed to obtain qualitative results. The method utilizes various components which allow for the collection of a sample from suspected contaminated areas.
07/03/14
20140186877
Compositions and methods for the biosynthesis of 1-alkenes in engineered microorganisms
Various 1-alkenes, including 1-nonadecene and 1-octadecene, are synthesized by the engineered microorganisms and methods of the invention. In certain embodiments, the microorganisms comprise a recombinant alpha-olefin-associated enzyme.
07/03/14
20140186875
Novel optical labeling molecules for proteomics and other biological analysis
The invention relates to compositions and methods useful in the labeling and identification of changes in protein levels, changes in enzyme activity, and changes in protein modification. The invention provides for highly soluble optical labeling molecules which are optionally cleavable after separation of mixtures of labeled proteins into components.
07/03/14
20140186870
In vivo proteomics
The application discloses methods, materials, and compositions for the labeling of molecules, for example, proteins, in living cells or in subcellular compartments of living cells. In particular, the application relates to proteomic analysis methods; materials and compositions and means based on direct tagging of unknown proteins with tagging enzymes (such as biotin ligase or a peroxidase) within the vicinity of a tagging substrate (such as a tyramide) within living cells, with optional targeting to specific subcellular locations by expression of genetic constructs..
07/03/14
20140186869
Method for inhibiting protease in biological sample containing pancreatic juice components
This method for inhibiting protease in a biological sample containing pancreatic juice components inhibits protease enzyme activity in the biological sample by adding at least one type of protease inhibitor having a sulfonyl fluoride group to the biological sample containing pancreatic juice components. In addition, this protease inhibitor for a biological sample containing pancreatic juice components is a compound having a sulfonyl fluoride group, has protease inhibitory activity, and is added to a biological sample containing pancreatic juice components in order to inhibit protease present in the biological sample.
07/03/14
20140186868
Method for adapting a hydrolytic enzyme to a component that stabilizes the hydrolytic enzyme
The stabilization of a hydrolytic enzyme in a liquid preparation is to be improved through a component that stabilizes the hydrolytic enzyme. This is accomplished by a method for adapting a hydrolytic enzyme to a component that stabilizes the hydrolytic enzyme, comprising the following method steps: a) providing a hydrolytic enzyme (starting enzyme) and a component that stabilizes the hydrolytic enzyme and that comprises a reversible inhibitor of the hydrolytic enzyme; b) changing the amino acid sequence of the hydrolytic enzyme in at least one position, by substitution, deletion or insertion; c) determining the relative activity of the hydrolytic enzyme from step b) and the relative activity of the starting enzyme in a liquid preparation; d) selecting the hydrolytic enzyme that has a reduced relative activity by comparison with the relative activity of the starting enzyme..
07/03/14
20140186866
Glucose control test strip
A control test strip for glucose that includes a cover that forms a fluid path when affixed to the test strip substrate. The fluid path includes a glucose deposit area formed by drying a glucose solution on to the cover or onto the test strip substrate.
07/03/14
20140186843
Methods, systems, and apparatus for identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof
Disclosed are locational or positional methods concerning crispr-cas systems, and apparatus therefor.. .
07/03/14
20140186831
Solid phases optimized for chemiluminescent detection
Solid supports for chemiluminescent assays are provided. The solid support includes a plurality of probes covalently or physically attached to the support surface and a chemiluminescent enhancing moiety incorporated onto the surface or into the bulk of the support.
07/03/14
20140186825
Labeled nucleotide analogs
Labeled reactant compositions, and particularly labeled nucleic acid reaction compositions that include structural components including double-stranded nucleic acids. In some embodiments, the structural components maintain potentially damaging labeling components sufficiently distal from the reactant portion of the molecule such that damaging effects of the label group on other reaction components, such as enzymes, are reduced, minimized and/or eliminated..
07/03/14
20140186436
Oral delivery of enzymes by nanocapsules for targeted metabolism of alcohol or toxic metabolites
The invention disclosed herein includes nanocomplexes that are designed include enzymes that have complementary functional attributes and methods for using these nanocomplexes. Illustrative examples include nanocomplexes that comprise both an alcohol oxidase enzyme as well as a catalase enzyme.
07/03/14
20140186433
Cosmetic treatment system and methods
A cosmetic treatment system is provided having ingredients that may prevent signs of aging, improve the aesthetic appearance of skin, and promote recovery from environmental stresses. The composition includes natural ingredients, including at least one ingredient or extract from rosemary; at least one ingredient or extract from centella, echinacea, alpinia or mixtures thereof; a dna repair enzyme; and at least one pharmaceutically or cosmetically acceptable vehicle.
07/03/14
20140186340
Methods and compositions for normalization of tumor vasculature by inhibition of loxl2
Disclosed herein are methods and compositions for increasing perfusion, reducing hypoxia, reducing permeability and increasing the integrity of vasculature; e.g., in a tumor. The compositions include inhibitors of the loxl2 enzyme.


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Enzyme topics: Modulation, Zinc Oxide, Nucleotide, Acetylsalicylic Acid, Test Strip, Chemical Reaction, Accommodation, Carbon Nanotube, Dinucleotide, Nicotinamide, Perhydrolase, Carotid Sinus, Neurotoxic, Neuromodulation, Renal Hypertension

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