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Endometrial

Endometrial-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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B1sp fusion protein therapeutics, methods, and uses
The University Of British Columbia
June 14, 2018 - N°20180162923

Provided are methods, uses and pharmaceutical compositions for treatment of cancer with a b1sp fusion protein in a biologically effective amount sufficient to cause cell death of a prostate cancer cell or to inhibit proliferation of the prostate cancer cells. The cancer may be prostate cancer, breast cancer, ovarian cancer, bladder cancer, kidney cancer, glioblastoma or endometrial cancer.
Organic compositions to treat kras-related diseases
Arrowhead Pharmaceuticals, Inc.
June 07, 2018 - N°20180153919

The present disclosure relates to rnai agents useful in methods of treating kras-related diseases such as a proliferative disease, including without limitation a solid or liquid cancer, adenocarcinoma, colorectal cancer, advanced and/or metastatic colorectal cancer, colon cancer, lung, non-small cell lung cancer and lung adenocarcinoma, acute myelogenous lung, bladder, brain, breast, cervical, endometrial, gastric, head and neck, kidney, leukemia, ...
Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells
Immunomedics, Inc.
May 31, 2018 - N°20180149657

Described herein are compositions and methods of use of anti-trop-2 antibodies or antigen-binding fragment thereof to isolate, enrich, detect, diagnose and/or characterize circulating tumor cells (ctcs) from patients with a trop-2 positive cancer. Preferably, the antibody is an rs7, 162-46.2 or mab650 antibody.
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New pharmaceutical use and pharmaceutical composition of pyrroloquinoline quinine, its derivatives and/or its salts
Nanjing Shupeng Lifescience Co.,ltd
May 24, 2018 - N°20180140596

The present invention relates to the use of pyrroloquinoline quinine (pqq), its derivatives and/or salts for the preparation of drugs for the treatment and/or prevention of endometriosis including adenomyosis, chocolate cyst of ovary, deeply infiltrating endometriosis and other type of endometriosis. In addition, the present invention relates to the use of pqq in combination with one or more ...
Method and apparatus for hysteroscopy and endometrial biopsy
Coopersurgical, Inc.
May 17, 2018 - N°20180132701

Methods and devices are described for performing a combined hysteroscopy and endometrial sampling. Techniques for improving visual images include forward facing fluid ports for clearing tissue debris and led positioning and design.
Scaffolds for uterine cell growth
Lehigh University
April 19, 2018 - N°20180105799

A method for growing polarized endometrial cells, said method comprising: (a) disposing endometrial cells on a scaffold, said scaffold comprising a silica-based glass composition, characterized by multi-modal porosity, said scaffold being to define a top side and a bottom side; (b) providing nutrients to said top and bottom sides of said scaffold and an environment to grow polarized endometrial cells ...
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Methods for treating cancer with rorgamma inhibitors
The Regents Of The University Of California
March 29, 2018 - N°20180085348

The present invention provides compositions, methods, and kits comprising one or more rorγ inhibitors, alone or in combination with one or more anticancer drugs, such as an anti-androgen drug, that are useful for treating cancer, e.g., prostate cancer, such as castration-resistant prostate cancer (crpc), and numerous other types of cancer including lung cancer, breast cancer, liver cancer, ...
System and method for endometrial ablation
Minerva Surgical, Inc.
March 01, 2018 - N°20180055561

A wall of a uterus is ablated by expanding a structure in the uterus and applying energy across the wall of the structure into the uterine wall. An exterior surface of the structure conforms to an inner wall of the uterus, and the energy may cause vapor to collect between the wall and the structure.
Use of substituted 2,3-dihydroimidazo[1,2-c]quinazolines
Bayer Healthcare Pharmaceuticals Inc.
February 15, 2018 - N°20180042929

The present invention relates to: use of a 2,3-dihydroimidazo[1,2-c]quinazoline compound, or of a pharmaceutical composition containing same, as a sole active agent, or of a combination of a) said compound or a pharmaceutical composition containing said compound and b) one or more further active agents, for the preparation of a medicament for the treatment or prophylaxis of endometrial ...
Method for the diagnosis of endometrial carcinoma
Hosmotic Srl
February 08, 2018 - N°20180038867

A method for the diagnosis of the endometrial carcinoma is disclosed.. .
Self-heating and hardening vibrating sensual stimulation devise
January 25, 2018 - N°20180021213

A medical, or fertility aid, or sensual device including: an outer cylindrical phallic shaped outer cover; a cylindrical phallic shaped liquid filled enclosed casing pocket; rechargeable vibrating/infrared/ultrasound core inserted into the outer cover, wherein the liquid filled pocket contains a ferrous metal disk which can be bent; and a sheath encasing the outer cover. One embodiment relates to ...
Msi-specific frameshift peptides (fsp) for prevention and treatment of cancer
Ruprecht-karls-universität Heidelberg
November 30, 2017 - N°20170340717

Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (msi). The vaccine contains an msi-specific frameshift peptide (fsp) generating humoral and cellular responses against tumor cells or a nucleic acid encoding said fsp.
Prevention, treatment, and amelioration of radiation induced enteritis
November 23, 2017 - N°20170333458

The present invention provides a new method of ameliorating and/or treating enteritis induced by radiation therapy, alone or in combination with other therapies, for the treatment oil for example, gastrointestinal malignancies, including colorectal, appendiceal, anal, or small bowel cancers; urogenital malignancies, including prostate, bladder, testicular, or penile cancers; gynecologic malignancies, including cervical, endometrial, ovarian, vaginal, or vulvar cancers; or ...
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Method of contraception
November 02, 2017 - N°20170312219

The invention is related to an improved method of contraception, for preventing or suppressing abnormal and/or irregular endometrial bleeding and achieving a rapid induction of amenorrhea by using an intrauterine delivery system comprising controlled release levonorgestrel over a prolonged period of time and at a therapeutic level required for contraception, and a sufficient amount of nsaid capable of suppressing ...
Endometrial stem cells and methods of making and using same
Xon Cells, Inc.
October 12, 2017 - N°20170290863

The invention provides pluripotent stem cells and methods for making and using pluripotent stem cells. Pluripotent stem cells, among other things, can differentiate into various cell lineages in vitro, ex vivo and in vivo.
Antibodies, pharmaceutical compositions and methods
Obi Pharma, Inc.
October 05, 2017 - N°20170283488

Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to stage-specific embryonic antigen 4 (ssea-4) are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics.
Anti-trop-2 antibody-drug conjugates and uses thereof
Immunomedics, Inc.
October 05, 2017 - N°20170281791

Described herein are compositions and methods of use of antibody-drug conjugates (adcs) comprising an anti-trop-2 antibody or antigen-binding fragment thereof, conjugated to one or more cytotoxic drugs. Preferably, the antibody is an rs7, 162-46.2 or mab650 antibody.
Usp14 as a biomarker for predicting recurrence in endometrial and ovarian cancer
Regents Of The University Of Minnesota
September 21, 2017 - N°20170269091

Usp14 is a biomarker for recurrent disease and inhibition of usp14 is of therapeutic benefit for women with endometrial or ovarian cancer.. .
Methods and materials for treating endometrial cancer
Mayo Foundation For Medical Education And Research
September 14, 2017 - N°20170260571

This document provides methods and materials for detecting and/or treating endometrial hyperplasia and/or endometrial cancer. For example, this document provides methods and materials for identifying a female mammal as having endometrial hyperplasia and administering a therapy (e.g., hormone therapy) to the female mammal.
Anti-clusterin antibodies and antigen binding fragments and their use to reduce tumor volume
National Research Council Of Canada
August 17, 2017 - N°20170233487

Novel antibodies and antigen binding fragments that specifically bind to clusterin are described. In some embodiments, the antibodies block the biological activity of clusterin and are useful in composition in certain cancers, more particularly in cancers, such as endometrial carcinoma, breast carcinoma, hepatocellular carcinoma, prostate carcinoma, a renal cell carcinoma, ovarian carcinoma, pancreatic carcinoma, and colorectal carcinoma.
Cancer therapeutics
University Of Virginia Patent Foundation
August 17, 2017 - N°20170233375

This invention relates to compounds that bind to wild-type cbfβ and inhibit cbfβ binding to runx proteins. The potent compounds of the invention inhibit this protein-protein interaction at low micromolar concentrations, using allosteric mechanism to achieve inhibition, displace wild-type cbfβ from runx1 in cells, change occupancy of runx1 on target genes, and alter gene ...
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