|| List of recent Electrophoresi-related patents
| Image capture for large analyte arrays|
Analyte arrays such as solutes in a slab-shaped gel following electrophoresis, and particularly arrays that are in excess of 3 cm square and up to 25 cm square and higher, are imaged at distances of 5 cm or less by either forming sub-images of the entire array and stitching together the sub-images by computer-based stitching technology, or by using an array of thin-film photoresponsive elements that is coextensive with the analyte array to form a single image of the array.. .
| Dishwashing liquid having bleaching catalyst and protease|
In a dishwashing liquid, the cleaning performance, in particular on bleachable stains such as, for example, tea stains, is to be improved. This succeeds using a dishwashing liquid which comprises a hydrogen peroxide source, a bleaching catalyst and a protease that, in native electrophoresis on a polyacrylamide gel, has a migration distance that is longer than the migration distance of the protease as per seq id no.
| Method for forming microcapsules for electrophoresis display|
An embodiment of the invention provides a method for forming microcapsules for electrophoresis display by forming microcapsules through a complex coacervation reaction between a sulfonated styrene maleic anhydride copolymer and gelatin, wherein a mass ratio of the sulfonated styrene maleic anhydride copolymer to the gelatin is 1:10˜10:1. The method of the embodiment of the invention not only can obtain microcapsules with good sealability and stability, but also can obtain microcapsules having evenly distributed particle sizes and low cost..
| High efficiency particle separating apparatus and method|
A particle separating apparatus and method are provided, which pass a fluid sample such as blood through a filter to remove foreign matter, and separate target particles by using a moff channel, and re-separate the separated target particles through dielectrophoresis. The particle separating apparatus includes a moff (multi orifice flow fractionation) channel including a multi orifice segment through which a fluid sample passes to discharge a primarily separated material that are target particles separated from the fluid sample, through a central passage; a dielectrophoresis channel including a pair of electrodes to which ac power is applied and forming an electric field in a flow channel connected to the central passage of the moff channel to re-separate the target particles from the primarily separated material discharged from the central passage of the moff channel through dielectrophoresis..
| Negative dielectrophoresis for selective elution of immumo-bound particles|
The procedure of dielectric electrophoresis (dielectrophoresis or dep) utilizes field-polarized particles that move under the application of positive (attractive) and/or negative (repulsive) applied forces. This invention uses negative dielectric electrophoresis (negative dielectrophoresis or ndep) within a microchannel separation apparatus to make particles move (detached) or remain stationary (attached).
| Crosslinked swellable polymer|
The invention is directed to stable crosslinked water-soluble swellable polymers, methods for making same, and their various uses in the hygiene and medical arts, gel electrophoresis, packaging, agriculture, the cable industry, information technology, in the food industry, papermaking, use as flocculation aids, and the like. More particularly, the invention relates to a composition comprising expandable polymeric microparticles having labile crosslinkers and stable crosslinkers, said microparticle mixed with a fluid and an unreacted tertiary crosslinker that is capable of further crosslinking the microparticle on degradation of the labile crosslinker so as to form a stable gel.
|Recombinase polymerase amplification|
This disclosure describes related novel methods for recombinase-polymerase amplification (rpa) of a target dna that exploit the properties of recombinase and related proteins, to invade double-stranded dna with single stranded homologous dna permitting sequence specific priming of dna polymerase reactions. The disclosed methods have the advantage of not requiring thermocycling or thermophilic enzymes, thus offering easy and affordable implementation and portability relative to other amplification methods.
|Detection of mirna using capillary electrophoresis with laser-induced fluorescence detection|
Disclosed is a method for detecting a mirna present in a sample in trace amounts and a kit for detecting the same. According to the present invention, the mirna present in the sample in trace amounts can be quantitatively analyzed in short time.
|Methods for production of proteins|
The current invention provides methods for producing a polypeptide as inclusion bodies in bacterial host cells. The present methods are carried out by forming a gene construct comprising the genetic sequence encoding a polypeptide operatively linked to that of an inclusion partner protein, such that host cells comprising the gene construct produce the polypeptide as intracellular inclusion bodies thereby facilitating rapid isolation and purification of recombinant proteins.
|Reagent applying device and reagent applying method for electrophoresis analysis|
To provide a reagent applying device and a reagent applying method for electrophoresis analysis which make it possible to apply a reagent with a simple configuration at low cost. A reagent supplying device for supplying a reagent to the surface of a gel in electrophoresis analysis includes a reagent applying tool which is a plate-shaped body.
|Microbial cell and particle selection system and method of use|
The invention comprises two key components: dielectrophoresis (dep) and reversible binding surfaces. Dep has become an important tool for trapping dielectric particles.
|Method of mutation detection in blood cell-free dna using primer extension (pe) and pcr|
A method of detecting mutation in blood cell-free dna, includes providing a serum sample, isolating dna from the serum sample, amplifying the dna by polymerase chain reaction (pcr), subjecting the pcr product to primer extension (pe), and separating the pe reaction product and identifying the mutation by gel electrophoresis. In order to improve accuracy and sensitivity, the pe reaction can be carried out by using a primer that blocks the extension of the wild or non-mutated sequence..
|Axial illumination for capillary electrophoresis|
System and method for fluorescent light excitation and detection from samples to enhance the numerical aperture and/or reduce the cross-talk of the fluorescent light.. .
|High speed, high resolution compositions, methods and kits for capillary electrophoresis|
The invention provides compositions, methods and kits for high speed, high resolution of analytes by capillary electrophoresis starting with uncoated capillaries. The compositions comprise a sieving component, comprising a non-crosslinked acrylamide polymer, and a surface interaction component, comprising at least one uncharged and non-crosslinked water-soluble silica-adsorbing polymer.
|Extended risk assessment panel for individualized treatment of cardiovascular disease, and methods related thereto|
Disclosed is a personalized diagnostic and treatment solution for cardiovascular disease. The invention comprises an extended cvd risk assessment panel, combining tests for traditional and new important risk markers, and methods for devising a personalized treatment plan for a patient via the use of a cvd diagnosis and treatment protocol algorithm.
|Software for the display of chromatographic separation data|
Techniques and systems for displaying chromatographic data using a graphical user interface are provided. Chromatographic separation data that represent multiple series of measurements for multiple samples can be displayed on a display device of a computer system as a series of bands, the bands being arranged to resemble output from an electrophoresis gel.
|Electrophoresis-gel-forming monomer solution, solution ejecting method, method for forming electrophoresis gel, electrophoresis gel, and electrophoresis reaction instrument|
A solution ejecting method includes a first ejection step of ejecting an electrophoresis-gel-forming monomer solution containing at least a monomer that forms a gel structure and a gel polymerization accelerator that activates a gel polymerization initiator and a second ejection step of ejecting a gel polymerization initiating solution containing the gel polymerization initiator onto the electrophoresis-gel-forming monomer solution.. .
|Plasmid-encoded neurotoxin genes in clostridium botulinum serotype a subtypes|
The present invention provides a novel isolated plasmid, wherein the plasmid is a native plasmid found in unique c. Botulinum type a strains and encode either bont/a3 or bont/a4 and bont/b.
|Methods and devices for multi-color, out-of-phase detection in electrophoresis|
The disclosure provides methods and devices for separating and detecting nucleic acid fragments labeled with a plurality of spectrally resolvable dyes using a single light source or multiple light sources. Use of a greater number of light sources increases the number of spectrally resolvable dyes that can be interrogated.
|Expanding cam lock for sealing slab gels in an electrophoresis apparatus|
An expanding cam lock for use with an electrophoresis system is disclosed herein. The cam lock allows the simultaneous use of multiple slab gel cassettes in first and second buffer core assemblies in an electrophoresis system while maintaining the necessary compressive force to create a liquid-tight seal between the anode and cathode buffer solutions.
|System for rapid high-resolution gel electrophoresis|
Electrophoretic systems, formulations and methods are described which allow a user to perform electrophoresis experiments under conditions of high voltage and with reduced run time. An electrophoretic system, formulation or method may be run at 50% higher field strength than comparable systems already in use in the art.
|Microfluidics with wirelessly powered electronic circuits|
Techniques, devices and systems are described for incorporating a printed circuit with a microfluidic device and wirelessly powering the microfluidic device. In one aspect, a microfluidic device includes a substrate with a fluidic channel to provide a path for a fluid with particles.
|Two-dimensional gel electrophoresis apparatus and method|
Two-dimensional gel electrophoresis apparatus includes an electrophoresis zone having four edges defined by a plurality of electrodes. A pair of opposed edges are defined by groups of discrete electrodes.
|High-throughput multi laser wave mixing detection methods and apparatus|
This invention relates to methods and apparatus of a combination of multi-laser wave mixing technology with diagnostic flow technologies with embodiments describing capillary electrophoresis. The unique combination of these technologies along with minute detection levels not yet been seen in the field..
|High-throughput single laser wave mixing detection methods and apparatus|
This invention relates to methods and apparatus of a combination of a single laser wave mixing technology with a diagnostic flow technologies with embodiments describing capillary electrophoresis. The unique combination of these technologies along with minute detection levels not yet been seen in the field..
|Ex-vivo multi-dimensional system for the separation and isolation of cells, vesicles, nanoparticles, and biomarkers|
Devices and techniques are described that involve a combination of multidimensional electrokinetic, dielectrophoretic, electrophoretic and fluidic forces and effects for separating cells, nanovesicles, nanoparticulates and biomarkers (dna, rna, antibodies, proteins) in high conductance (ionic) strength biological samples and buffers. In disclosed embodiments, a combination of continuous and/or pulsed dielectrophoretic (dep) forces, continuous and/or pulsed field dc electrophoretic forces, microelectrophoresis and controlled fluidics are utilized with arrays of electrodes.
|Modified electrode buffers for stain-free protein detection in electrophoresis|
Proteins that are electrophoretically separated in a gel are derivatized to produce fluorescent emissions by incorporating halo-substituted organic compounds into one or both of the electrode buffer solutions at the two ends of the gel. The halo-substituted compounds used are ones that bear an electric charge at the ph of the buffer solutions and gel, and the polarity of the charge on the compounds is such that the compounds migrate from the electrode buffer into the gel under the electrophoretic influence concurrently with the migration of the proteins into the gel.
A particle transporter based on travelling-wave dielectrophoresis is provided. The particle transporter includes a first collection electrode and a second collection electrode on a substrate.
A particle transporter based on travelling-wave dielectrophoresis is provided. The particle transporter includes a common electrode, a plurality of left switch electrodes and a plurality of right switch electrodes.
|Compositions and methods for improving resolution of biomolecules separated on polyacrylamide gels|
Gels, such as polyacrylamide gels, are provided that include linear polyacrylamide in the stacking gel. Native gels that include linear polyacrylamide in the stacker can be used to separate biomolecular complexes, such as protein complexes.
|Capillary tubes for electrophoresis|
The present invention relates to a plastic capillary tube for capillary electrophoresis, in which the plastic capillary tube has an inlet opening and an outlet opening and, furthermore, has at least one hole in the capillary tube wall and the diameter of the hole on the inside of the capillary tube wall dl(innen) lies in the range from 0.5 μm to 30 μm.. .