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Elastin topics
Mometasone Furoate
Medical Device
Polypeptide
Azelastine
Antibodies
Aortic Aneurysm
Polyclonal
Sample Preparation
Control Group
Refractory
Spectrometry
Internal Standard
Elastic Fiber
Chronic Obstructive Pulmonary Disease
Chronic Bronchitis

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Elastin patents



      
           
This page is updated frequently with new Elastin-related patent applications. Subscribe to the Elastin RSS feed to automatically get the update: related Elastin RSS feeds. RSS updates for this page: Elastin RSS RSS


Date/App# patent app List of recent Elastin-related patents
09/18/14
20140268168
 Apparatus and methods for optical coherence tomography and two-photon luminescence imaging patent thumbnailApparatus and methods for optical coherence tomography and two-photon luminescence imaging
Exemplary embodiments of the present disclosure include a combined catheter-based optical coherence tomography-two-photon luminescence (oct-tpl) imaging system. Exemplary embodiments further include methods to detect, and further characterize the distribution of cellular components (e.g., macrophage, collagen/elastin fiber, lipid droplet) in thin-cap fibroatheromas with high spatial resolution in vivo..
09/11/14
20140255953
 Granzyme a and granzyme b diagnostics patent thumbnailGranzyme a and granzyme b diagnostics
A method for identifying a subject being at risk for or having a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease is provided. The method may include determining the concentration of gra and/or grb in a blood or serum sample from said subject; and comparing the concentrations to the corresponding concentration in a control sample, wherein an elevated concentration of gra and/or grb may be indicative of a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease.
08/21/14
20140235547
 In vivo synthesis of elastic fiber patent thumbnailIn vivo synthesis of elastic fiber
Disclosed herein are methods of restoring elasticity in tissue using tropoelastin containing compositions.. .
08/07/14
20140220155
 Vaginal tissue rejuvenation compositions and methods patent thumbnailVaginal tissue rejuvenation compositions and methods
A method of stimulating elastin and/or collagen production in the tissues of the vagina, comprising the steps of providing a composition including at least one of a water soluble zinc salt such as zinc sulfate and a peroxisome proliferator-activated receptor beta/delta (ppar 13/8) agonist, and administering the composition to the tissue of the vagina. Compositions for stimulating 5 elastin and/or collagen production in the tissues of the vagina are also disclosed..
08/07/14
20140220045
 Compositions of a peptide targeting system for treating cancer patent thumbnailCompositions of a peptide targeting system for treating cancer
This invention describes a protein nanoparticle system for targeting sirna or other drugs into tumors. The basis of the protein system is elastin-like peptides that self-assemble once exposed to the nucleic acid of the sirna.
07/10/14
20140194370
 Silk-elastin like protein polymers for embolization and chemoembolization to treat cancer patent thumbnailSilk-elastin like protein polymers for embolization and chemoembolization to treat cancer
A chemoembolic agent is disclosed that includes an injectable, recombinantly synthesized silk-elastin like protein copolymer and one or more chemotherapeutic agents. Upon injection, the chemoembolic agent blocks the tumor vasculature, including the capillary bed, and may optionally release chemotherapeutic agents.
07/10/14
20140193477
 Collagen based materials and uses related thereto patent thumbnailCollagen based materials and uses related thereto
This disclosure relates to materials fabricated from collagen and uses relates thereto. Typically, layers of collagen are stretched during a curing period and optionally coated or impregnated with an elastin like protein.
06/12/14
20140158117
 Compositions comprising azelastine and methods of use thereof patent thumbnailCompositions comprising azelastine and methods of use thereof
The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize or mask the unpleasant bitter taste associated with post-nasal drip, of the compositions, into the oral cavity, upon intranasal or ocular administration of the compositions.
06/05/14
20140155335
 Elastin protective polyphenolics and methods of using the same patent thumbnailElastin protective polyphenolics and methods of using the same
Dermal fibroblasts permanently loose their ability to synthesize elastin, the major component of elastic fibers, shortly after puberty. This progressive loss of elastic fibers cannot be replaced, resulting in the physical signs of aging.
04/17/14
20140106001
 Marine extract compositions and methods of use patent thumbnailMarine extract compositions and methods of use
Compositions comprising extracts from marine organisms show beneficial effects on skin ailments. Fine lines, wrinkles, and sagging in skin are improved with the application of compositions with marine extracts.
04/10/14
20140100170
Plant-derived elastin binding protein ligands and methods of using the same
The present invention describes novel plant derived elastin-like peptides and peptidomimetics that may serve as functional ligands for elastin receptors and stimulate elastogenesis. The novel plant derived peptides provide an alternative (non-animal derived) source of gxxpg (seq id no.
03/06/14
20140065069
Materials and methods relating to cardiovascular imaging
The invention provides conjugates for imaging plaques, such as cardiovascular plaques, as well as associated pharmaceutical compositions. Other aspects of the invention include methods for administering and imaging such conjugates and compositions, and using the imaging to characterise plaques.
02/27/14
20140056916
Aldosterone induced vascular elastin production
Compositions and methods for inducing the deposition of elastin by administering compositions including a mineralocorticoid, such as, for example, aldosterone and, optionally, a secondary active agent for enhancing or modulating the effect of the mineralocorticoid are described herein.. .
01/30/14
20140030236
Derivation and maturation of synthetic and contractile vascular smooth muscle cells from human pluripotent stem cells
Embryonic vascular smooth muscle cells (vsmcs) have a synthetic phenotype (syn-vsmc), but in adults, they commit to the mature contractile phenotype (con-vsmc). Con-vsmcs differ from syn-vsmc derivatives in condensed morphology, prominent filamentous cytoskeleton proteins, elastin production and assembly elastin, low proliferation, numerous active caveolae, enlarged endoplasmic reticulum, ample stress fibers and bundles, as well as high contractility.
01/16/14
20140018909
Treatment to render implants resistant to diabetes
Disclosed is a medical device treated with a phenolic compound and a process for treating a device with the phenolic compound. For example, a collagen or elastin-based scaffold can be treated with pentagalloyl glucose (pgg).
01/16/14
20140017263
Delivery agents for targeted treatment of elastin degradation
Methods and delivery agents for treatment of connective tissue that includes elastic fibers are described. Delivery agents are nano- or micro-sized particles that include a biologically active compound useful in treatment of degraded elastic fibers and an anchoring agent at a surface that binds at or near the area of degraded elastic fibers.
12/19/13
20130338221
Photoaging protective composition containing chromenes derived from sargassum horneri
There is provided a photoaging protective composition having an effect of protecting photoaging on skin cell, the composition including chromenes derived from sargassum horneri. Specifically, for the photoaging protective composition, sargachromanol d and sargachromanol e isolated from sargassum horneri, brown algae exhibits activity of inhibiting mmps, increase an expression of a collagen synthetic marker, such as procollagen and type i collagen in fibroblasts treated with uv-a, or increases elastin by controlling elastase.
12/19/13
20130338089
Methods and compounds for modulating the secretion or expression of adhesion proteins or angiopoietins of cells
This invention provides methods, processes, compounds and compositions for modulating the gene expression or secretion of adhesion proteins, angiopoietins or their receptors to cure diseases, for anti-angiogenesis and for treating parasites, wherein the adhesion proteins or receptors comprise fibronectin, integrins family, myosin, vitronectin, collagen, laminin, glycosylation cell surface proteins, polyglycans, cadherin, heparin, tenascin, cd 54, cam, elastin and fak; wherein the angiopoietins comprise angiopoietin 1, angiopoietin 2, angiopoietin 3, angiopoietin 4, angiopoietin 5, angiopoietin 6, angiopoietin 7, angiopoietin-like 1, angiopoietin-like 2, angiopoietin-like 3, angiopoietin-like 4, angiopoietin-like 5, angiopoietin-like 6, and angiopoietin-like 7; wherein the cancers comprise breast cancer, leukocyte cancer, liver cancer, ovarian cancer, bladder cancer, prostate cancer, skin cancer, bone cancer, brain cancer, leukemia cancer, lung cancer, colon cancer, cns cancer, melanoma cancer, renal cancer, cervical cancer, esophageal cancer, testicular cancer, spleenic cancer, kidney cancer, lymphatic cancer, pancreas cancer, stomach cancer and thyroid cancer.. .
12/05/13
20130323749
Granzyme a and granzyme b diagnostics
A method for identifying a subject being at risk for or having a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease is provided. The method may include determining the concentration of gra and/or grb in a blood or serum sample from said subject; and comparing the concentrations to the corresponding concentration in a control sample, wherein an elevated concentration of gra and/or grb may be indicative of a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease.
11/28/13
20130315822
N-alkoxyamide conjugates as imaging agents
The present disclosure is directed to compounds, diagnostic agents, and related methods. In some cases, methods for treating patients are provided.
11/21/13
20130310538
Methods and compositions for delivering active agents with enhanced pharmacological properties
Provided herein are methods of enhancing in vivo efficacy of an active agent, comprising: administering to a subject an active agent that is coupled to a bioelastic polymer or elastin-like peptide, wherein the in vivo efficacy of the active agent is enhanced as compared to the same active agent when administered to the subject not coupled to (or not associated with) a bioelastic polymer or elp.. .
11/21/13
20130309332
New use of an extract of plant origin of globularia and method for obtaining said extract by in vitro plant culture
According to the present invention the extract of plant origin of the globularia genus is used for a non-therapeutic cosmetic treatment of the skin and/or appendages. Preferably the species is globularia cordifolia and the extract is obtained by in vitro plant culture.
11/07/13
20130296528
Preparation and/or formulation of proteins cross-linked with polysaccharides
Therapeutic compositions and/or formulations are provided, comprising: at least one cross-linked protein matrix, wherein the at least one cross-linked protein matrix comprises at least one protein residue and at least one saccharide-containing residue, and methods of producing the same. The cross-linked protein matrix may be derived from cross-linking a full length or substantially full length protein, such as tropoelastin, elastin, albumin, collagen, collagen monomers, immunoglobulins, insulin, and/or derivatives or combinations thereof, with a saccharide containing cross-linking agent, such as a polysaccharide cross-linking agent derived from, for example, hyaluronic acid or a cellulose derivative.
11/07/13
20130295122
Elastin digest compositions and methods utilizing same
The present invention provides compositions for the therapeutic and/or cosmetic treatment of elastin comprising tissues. Therapeutic and cosmetic compositions comprising an elastin digest stimulate the endogenous production of elastin and appear to enhance the elasticity of the skin and provide an external supply of peptide precursors of elastin that penetrate into the tissue to which it is applied.
11/07/13
20130295117
Aldosterone induced elastin production
Compositions and methods for inducing the deposition of elastin in skin by administering compositions including a mineralocorticoid, such as, for example, aldosterone and, optionally, a secondary active agent for enhancing or modulating the effect of the mineralocorticoid are described herein.. .
10/24/13
20130280782
Protein-based conjugates and self-assembled nanostructures
The present disclosure provides protein-containing compositions, methods and uses thereof. A conjugate comprises a globular protein conjugated with a polymer that preserves the folded and functional structure of a protein.
10/17/13
20130273586
Methods of validating candidate compounds for use in treating copd and other diseases
The present invention relates to methods of diagnosing, monitoring, and treating elastin fiber injuries. In additional preferred embodiments, the present invention relates to methods of validating candidate compounds for use in treating chronic obstructive pulmonary disease (copd), chronic bronchitis, emphysema, refractory asthma, and other related diseases.
10/17/13
20130273580
Elisa assay kit, elisa for determining desmosine levels from urine samples and diagnostic urine assays for aneurysms
Improved elisa assay formats are described that provide for effective measurement of desmosine, an elastin degradation product, in urine samples. The urine samples can be effectively introduced into the assay with little or no sample preparation.
10/03/13
20130259915
Method for the treatment of skin
A composition for the treatment of skin comprises a non-emulsified, aqueous suspension of retinol. The composition may further include at least one protein species, and some proteins used in the composition include collagen and elastin.
09/26/13
20130253429
Medical devices to facilitate tissue stabilization for heart failure
Methods and devices for the stabilization of heart tissue to treat congestive heart failure using a therapeutic composition are discussed. The therapeutic composition can comprise an elastin stabilization agent, a collagen stabilization agent, or a combination thereof and be applied to the pericardium, to the outer surface of the myocardium, or a combination thereof using a catheter type of device with an attached reservoir.
09/26/13
20130253053
Method of treating skin with microrna modulators
Methods for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ active agents that suppress or down-regulate microrna expression in dermal fibroblast, resulting in enhanced production of collagen, elastin and/or fibrillin in the skin. Also provided are methods for screening for activity against specific micrornas and the methods of using active agents identified by the screening protocol in the treatment of skin..
09/26/13
20130252929
Pharmaceutical composition including mometasone furoate and azelastine hydrochloride for nasal administration
The present invention provides a pharmaceutical composition for nasal administration comprising mometasone furoate and azelastine hydrochloride, wherein the pharmaceutical composition comprises thaumatin as an agent for reducing bitterness and irritation.. .
09/19/13
20130245750
Biomaterials with enhanced properties and devices made therefrom
Biomaterials with enhanced properties such as improved strength, flexibility, durability and reduced thickness are useful in the fabrication of biomedical devices, particularly those subjected to continuous or non-continuous loads where repeated flexibility and long-term durability are required. These enhanced properties can be attributed to elevated levels of elastin, altered collagen types, and other biochemical changes which contribute to these enhanced properties.
09/19/13
20130245616
Method for picosecond and femtosecond laser tissue welding
A method for welding tissue wounds in an animal. The method comprises joining edges of a tissue wound and irradiating the tissue wound and tissue surrounding the tissue wound with a pulsed laser.
08/15/13
20130210747
Methods and therapeutics comprising ligand-targeted elps
Disclosed herein are novel methods and compositions for targeting drug delivery systems to specific cells. One aspect relates to a drug delivery system comprising an elastin-like peptide (elp) component and a ligand selected from the group consisting of miga and knob capable of either drug encapsulation or drug attachment.
08/01/13
20130197359
Solid lipid nanoparticles including elastin-like polypeptides and use thereof
Solid lipid nanoparticles (slns) including elastin-like polypeptides, compositions comprising the slns, and uses thereof are provided.. .
08/01/13
20130197102
3d matrices of human elastin-like polipeptides and method of preparation thereof
3d matrices or hydrogels made of human elastin-like polypeptides and their preparation are described. Said matrices can be obtained by enzymatic cross-linking of such polypeptides and can be used in the biomedical and pharmaceutical fields as support the growth of cells, isolated or as multicellular association, both on the surface and inside the matrix.
07/18/13
20130184199
Insulin receptor induced elastin production
Compositions and methods for modulating the deposition of elastin by administering compositions including insulin receptor agonists are described herein.. .
07/11/13
20130178416
Fusion peptide therapeutic compositions
Therapeutic compositions containing fusion proteins (fps) including elastin-like peptides (elps) and peptide active therapeutic agents, and methods of making and using such compositions and fusion proteins. Therapeutic compositions of such type enable improved efficacy of the peptide active therapeutic agent to be achieved, in relation to the peptide active therapeutic agent alone.
07/04/13
20130172274
Methods and compositions for delivering active agents with enhanced pharmacological properties
Provided herein are methods of enhancing in vivo efficacy of an active agent, comprising: administering to a subject an active agent that is coupled to a bioelastic polymer or elastin-like peptide, wherein the in vivo efficacy of the active agent is enhanced as compared to the same active agent when administered to the subject not coupled to (or not associated with) a bioelastic polymer or elp.. .
07/04/13
20130171281
Compositions comprising an nfkb-inhibitor and a tropoelastin promoter
The present invention relates to a composition comprising an nfκb-inhibitor and a tropoelastin promoter, and methods of treating signs of skin aging using said compositions.. .
07/04/13
20130167838
Nasal formulation
This invention relates to a solution formulation for nasal administration comprising azelastine, beclomethasone dipropionate, a co-solvent, an acid and an hfa propellant.. .
06/27/13
20130164340
Tropoelastins and uses thereof
The present invention relates to biocompatible polymeric scaffold materials, methods for making the materials and methods of using the materials. More particularly, the present invention relates to implants and grafts comprising polymeric scaffold materials of cross-linked human tropoelastin polypeptides and methods of making and using the same.
06/06/13
20130143802
Fusion peptide therapeutic compositions
Therapeutic compositions containing fusion proteins (fps) including elastin-like peptides (elps) and peptide active therapeutic agents, and methods of making and using such compositions and fusion proteins. Therapeutic compositions of such type enable improved efficacy of the peptide active therapeutic agent to be achieved, in relation to the peptide active therapeutic agent alone.
05/23/13
20130130384
Temperature responsive sheet that displays reversible properties and cell sheet production method using same
A temperature responsive sheet is disclosed that comprises a chemically modified water-soluble elastin obtained by n-acylating at least some of the primary amines and secondary amines contained in a high molecular weight water-soluble elastin molecule and coupling some or all of carboxyl groups contained in the molecule with a glycine alkyl ester. Also is disclosed a process for producing a cell sheet that comprises preparing above the temperature responsive sheet a film that functions as a scaffold for animal cells, culturing specific cells on the film so as to prepare a cell sheet, and subsequently separating the cell sheet and the temperature responsive sheet comprising the chemically modified water-soluble elastin under conditions of no greater than the culturing temperature for the cells..
04/25/13
20130103079
Biomimetic multiple strand fiber mesh and sutures
A material comprising two or more fibers, wherein each of the fibers has a mechanical modulus, and the mechanical modulus of at least one fiber is higher than the mechanical modulus of another fiber. The higher modulus fiber has a longer length than the lower modulus fiber.
04/25/13
20130102993
Liposome comprising elastin-like polypeptide and tumor cell targeting material and use thereof
A liposome including an elastin-like polypeptide (elp) and a tumor cell targeting material, a pharmaceutical composition including the liposome, and a method of delivering an active agent to a target site using the liposome.. .
04/25/13
20130102898
Liposome including elastin-like polypeptides and use thereof
A liposome comprising elastin-like polypeptides, a pharmaceutical composition comprising the liposome, and a method of delivering active agents to a target site using the liposome.. .
04/25/13
20130101666
Liposome including elastin-like polypeptide conjugated to moiety containing hydrophobic group, chemosensitizer and anticancer agent and use thereof
A liposome including a lipid bilayer, an elastin-like polypeptide (elp) conjugated to a hydrophobic moiety; a chemosensitizer; and an anticancer agent, a pharmaceutical composition including the same, and a method of delivering a chemosensitizer and an anticancer agent to a target site of a subject by using the liposome.. .
04/04/13
20130085104
Therapeutic agents comprising elastin-like peptides
The present invention provides therapeutic agents and compositions comprising elastin-like peptides (elps) and therapeutic proteins. In some embodiments, the therapeutic protein is a glp-1 receptor agonist, insulin, or factor vii/viia, including functional analogs.
04/04/13
20130085099
Therapeutic agents comprising elastin-like peptides
The present invention provides therapeutic agents and compositions comprising elastin-like peptides (elps) and therapeutic proteins. In some embodiments, the therapeutic protein is a glp-1 receptor agonist, insulin, or factor vii/viia, including functional analogs.
03/28/13
20130079277
Therapeutic agents comprising elastin-like peptides
The present invention provides therapeutic agents and compositions comprising elastin-like peptides (elps) and therapeutic proteins. In some embodiments, the therapeutic protein is a glp-1 receptor agonist, insulin, or factor vii/viia, including functional analogs.
03/21/13
20130071500
Compositions and methods for treating signs of skin aging
The invention relates to methods and compositions for treating skin aging, said compositions comprising at least one tropoelastin promoter and at least one tropoelastin crosslinker.. .
02/28/13
20130052288
Collagen and elastin stimulating compositions and uses thereof
Methods and compositions for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ a botanical extract of justicia ventricosa, archidendron clypearia, abrus fruticulosus, or combinations thereof and a cosmetically acceptable vehicle.. .
02/14/13
20130040891
Chemically modified water-soluble elastin, mixed gel of chemically modified water-soluble elastin and collagen, and process for producing same
A chemically modified water-soluble elastin/collagen mixed gel obtained by mixing a collagen with a chemically modified water-soluble elastin that is obtained by subjecting to n-acylating some or all of the primary amines and secondary amines contained in the molecule of a high molecular weight water-soluble elastin and coupling some or all of the carboxyl groups contained in the molecule with the amino group of an amino acid alkyl ester.. .
01/31/13
20130029952
Combination of azelastine and mometasone for nasal administration
A pharmaceutical product or formulation, which comprises azelastine or a pharmaceutically acceptable salt, solvate or physiologically functional derivative thereof, and a steroid, or a pharmaceutical acceptable salt, solvate or physiologically functional derivative thereof, preferably the product or formulation being in a form suitable for nasal or ocular administration.. .
01/31/13
20130029951
Combination of azelastine and ciclesonide for nasal administration
A pharmaceutical product or formulation, which comprises azelastine or a pharmaceutically acceptable salt, solvate or physiologically functional derivative thereof, and a steroid, or a pharmaceutical acceptable salt, solvate or physiologically functional derivative thereof, preferably the product or formulation being in a form suitable for nasal or ocular administration.. .
01/31/13
20130029420
Method of culturing vascular smooth muscle cells, culture device and medical material obtained by the culture
There is provided a method for culturing vascular smooth muscle cells while maintaining their normal function, and a culture device and regenerative medical material for the same. The method takes advantage of vascular smooth muscle cell recognition of elastin as an extracellular matrix.
12/31/69
20120149690

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12/31/69
20120083479

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12/31/69
20120065177

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Popular terms: [SEARCH]

Elastin topics: Mometasone Furoate, Medical Device, Polypeptide, Azelastine, Antibodies, Aortic Aneurysm, Polyclonal, Sample Preparation, Control Group, Refractory, Spectrometry, Internal Standard, Elastic Fiber, Chronic Obstructive Pulmonary Disease, Chronic Bronchitis

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This listing is a sample listing of patent applications related to Elastin for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Elastin with additional patents listed. Browse our RSS directory or Search for other possible listings.
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