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This page is updated frequently with new Elan-related patent applications. Subscribe to the Elan RSS feed to automatically get the update: related Elan RSS feeds. RSS updates for this page: Elan RSS RSS


Compositions and methods for treatment of vitiligo

Compositions and methods for treatment of vitiligo

Agents, compositions and devices for temporary coloring local hair areas

Kampalook

Agents, compositions and devices for temporary coloring local hair areas


Date/App# patent app List of recent Elan-related patents
07/23/15
20150202290 
 Method for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor patent thumbnailMethod for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor
The invention relates to methods of treating melanoma using a herpes simplex virus in combination with an immune checkpoint inhibitor.. .
Amgen Inc.


07/23/15
20150202187 
 Compositions and methods for treatment of vitiligo patent thumbnailCompositions and methods for treatment of vitiligo
Compositions and methods are disclosed for treating hypomelanotic conditions such as vitiligo and promoting melanogenesis.. .

07/23/15
20150201729 
 Agents, compositions and devices for temporary coloring local hair areas patent thumbnailAgents, compositions and devices for temporary coloring local hair areas
Hair-coloring applicators comprising a shield to protect the scalp, polymers of tannic acid having iron ions bound thereto, hair-coloring compositions comprising same and/or melanoidin, and novel alcohol-free carriers, are disclosed, as well uses thereof for coloring hair.. .
Kampalook Ltd.


07/16/15
20150198598 
 Kit for diagnosing malignant melanoma patent thumbnailKit for diagnosing malignant melanoma
Provided is a kit for diagnosing at a high reproducibility, said kit being produced by preparing a monoclonal antibody against gpc3 and a monoclonal antibody against sparc that are superior in quality stability to commercially available and commonly employed antibodies, and using these antibodies.. .
National Cancer Center


07/16/15
20150197520 
 Pyrazolopyridine and pyrazolopyrimidine derivatives as melanocortin-4 receptor modulators patent thumbnailPyrazolopyridine and pyrazolopyrimidine derivatives as melanocortin-4 receptor modulators
Wherein x, r1, r2, and r3 are as defined herein, or a pharmaceutically acceptable salt thereof to allow the drug to penetrate the cell membrane; or a prodrug, or the compound is labeled with a detectable label or an affinity tag thereof. Also disclosed is a pharmaceutical composition, a method of treating a disorder mediated by melanocortin-4 receptors, and a method of treating obesity using the compounds described..

07/16/15
20150196545 
 Method of treating cancer patent thumbnailMethod of treating cancer
This invention is directed to the treatment of cancer, particularly ocular melanoma, with a dual inhibitor of met and vegf such as compound 1.. .
Exelixis, Inc.


07/16/15
20150196351 
 Method and  treating medical conditions patent thumbnailMethod and treating medical conditions
A method and apparatus for treating a condition in a patient such as bph, irretractable infection, cyst, fibroid, or any mass such as prostate or breast cancer, skin cancer, melanoma, or any other soft tissue cancerous or benign mass, employs a unique, three-dimensional software-controlled electronic amplifier array using arbitrary waveforms that dynamically and proportionally steer electrical currents by using two or more current vector paths, sequentially or simultaneously, through a defined area containing electrically-conductive ionic solutions so as to obtain 100% thermal heating or hyperthermia through the defined area. The condition is treated or a mass is destroyed with a minimally-invasive treatment which requires no radiation or chemotherapy which could be harmful to the patient..

07/16/15
20150196031 
 Screening assay for insecticides patent thumbnailScreening assay for insecticides
The present invention relates to polypeptides, preferably from drosophila melanogaster (dmshal) as target for insecticides.. .
Basf Se


07/09/15
20150191797 
 Systems and methods for diagnosing a predisposition to colon cancer patent thumbnailSystems and methods for diagnosing a predisposition to colon cancer
Systems and methods for diagnosing or characterizing a predisposition to colon cancer are provided. Cell nuclei may be evaluated for the presence or quantity of gamma-h2ax foci or their total gamma-h2ax levels.
Institute For Cancer Research D/b/a The Research Institute Of Fox Chase Cancer Center


07/02/15
20150186827 
 Data-driven targeting of energy programs using time-series data patent thumbnailData-driven targeting of energy programs using time-series data
A method for enrolling utility customers in utility demand response or energy efficiency programs based on time-series consumption data includes collecting from smart meter sensors time-series utility consumption data from individual utility customers, extracting features from the consumption data, generating a probabilistic response model for each customer representing a relationship between the extracted features and customer program performance by estimating parameters of a response distribution, solving an optimization problem for each customer using the estimated response distribution to achieve a targeting objective, and enrolling selected customers in programs based on the solution to the optimization problem.. .
The Board Of Trustees Of The Leland Stanford Junior University


07/02/15
20150185218 

Methods and system for detecting melanoma


Use of the method for detecting melanoma in skin samples is also disclosed.. .

07/02/15
20150185217 

Myeloperoxidase, a risk indicator for cardiovascular disease


Diagnostic tests for characterizing an individual's risk of developing or having a cardiovascular disease. In one embodiment the present diagnostic test comprises determining the level of myeloperoxidase (mpo) activity in a bodily sample obtained from the individual or test subject.
The Cleveland Clinic Foundation


07/02/15
20150185204 

Circulating tumor cell diagnostics for lung cancer


The present invention provides methods for diagnosing lung cancer in a subject comprising (a) generating circulating tumor cell (ctc) data from a blood sample obtained from the subject based on a direct analysis comprising immunofluorescent staining and morphological characteristics of nucleated cells in the sample, wherein ctcs are identified in context of surrounding nucleated cells based on a combination of the immunofluorescent staining and morphological characteristics; (b) obtaining clinical data for the subject; (c) combining the ctc data with the clinical data to diagnose lung cancer in the subject.. .
The Board Of Trustees Of The Leland Stanford Junior University


07/02/15
20150184511 

Well testing and production apparatus and method


A well testing device for conducting well test operations on an oil, gas, or water well including a production flowline. A conduit guides fluids from the production flowline to the well test device and then back to the flowline.
Cameron Systems (ireland) Limited


07/02/15
20150184343 

Methods for removing hemicellulose


A method for treating a cellulosic material comprises extracting the cellulosic material with an extractant to selectively extract hemicellulose therein and separating the extracted hemicellulose to form a cellulosic product comprising less hemicellulose than the cellulose-containing material. The extractant comprises an amine oxide and a non-solvent.
Celanese International Corporation


07/02/15
20150184337 

Methods for removing hemicellulose


A method for treating a cellulosic material comprises extracting the cellulosic material with an extractant to selectively extract hemicellulose therein and separating the extracted hemicellulose to form a cellulosic product comprising less hemicellulose than the cellulose-containing material. The extractant comprises an ionic liquid and a non-solvent.
Celanese International Corporation


07/02/15
20150184131 

Enhanced efficiency of induced pluripotent stem cell generation


Human somatic cells are reprogrammed to become induced pluripotent stem cells (ips cells) by the introduction of a minicircle dna vector. Cells of interest include adipose stem cells..
The Board Of Trustees Of The Leland Stanford Junior University


07/02/15
20150184015 

Waterproofing coating compositions


A coating composition comprises an emulsion copolymer of a monomer mixture comprising at least one vinyl ester, ethylene, and a stabilizing system. The stabilizing system comprises at least one polyvinyl alcohol.
Celanese Emulsions Gmbh


07/02/15
20150183874 

Humanized and chimeric monoclonal antibodies to cd47


Humanized or chimeric anti-cd47 monoclonal antibodies are provided. The antibodies bind to and neutralize human cd47, and find use in various therapeutic methods.
The Board Of Trustees Of The Leland Stanford Junior University


07/02/15
20150183793 

Compounds and methods for kinase modulation, and indications therefor


Compounds and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof are active on one or more of fms, kit, flt3, trka, trkb and trkc kinase protein.
Plexxikon Inc.


07/02/15
20150183727 

Method for the preparation of 1-aryl-1-alkyl-2-alkyl-3-dialkylaminopropane compounds


The present invention refers to the preparation of 1-aryl-1-alkyl-2-alkyl-3-dialkylamino-propane compounds, such as tapentadol, using a diastereoselective eschenmoser-claisen or ireland-claisen rearrangement.. .
Siegfried Ag


07/02/15
20150183655 

Microparticles and a sytem and the synthesis of microparticles


There is provided a method of producing microparticles using an emulsion based synthesis route including: providing a first fluid phase and a second fluid phase, wherein the first fluid phase is a continuous phase and the second fluid phase is a dispersed phase comprising a dispersed material, wherein the continuous phase is immiscible with the dispersed phase; mixing the first continuous phase and the second dispersed phase in the presence of a surfactant in a shear device to form an emulsion of droplets of controllable size and having a narrow drop size distribution; drying the emulsion to form microparticles of controllable size and having narrow size distribution, and wherein the microparticles may comprise spherical, crumpled, dimpled, porous or hollow microparticles morphology. Also provided is a system including shear device and drying arrangement.
University College Dublin, National University Of Ireland, Dublin


07/02/15
20150182987 

Movable mask for a thermal and/or kinetic coating system


The invention relates to a mask for a coating system having a covering device for an area not to be coated of a substrate to be coated, having a working side exposed to the material flow of the coating material, wherein the covering device for the area not to be coated is comprised of at least one disk that can be rotated, the disk upper side of which is positioned vertically to the material flow of the coating material. A further aspect of the invention includes a thermal and/or kinetic coating system having at least one spray device, and a corresponding method for producing a coated substrate..
Wieland-werke Ag


07/02/15
20150182634 

Molecular design and chemical synthesis of pharmaceutical-ligands and pharmaceutical-pharmaceutical analogs with multiple mechanisms of action


Multi-phase and single-phase chemical reaction schemes have been developed for the synthesis of pharmaceutical-ligand analogs, pharmaceutical-pharmaceutical analogs, and similar molecular-molecular analogs that possess multiple mechanisms of action. The multi-phase organic chemical reaction schemes include relatively mild reaction conditions, high end product yields, and comparatively rapid completion of chemical reactions, which are all of particular utility for the synthesis of preparations including covalent pharmaceutical-receptor ligand or pharmaceutical-immunoglobulin analogs.

07/02/15
20150182614 

Vaccine for prophylaxis or treatment of an allergen-driven airway pathology


The present invention relates to a life attenuated bordetella pertussis vaccine which is deficient for tracheal cytotoxin (tct), pertussis toxin (ptx), and dermonecrotic toxin (dnt) for prophylaxis or treatment of an allergen-driven airway pathology.. .
National University Of Ireland Maynooth


07/02/15
20150182587 

Methods for treating reperfusion injuries


The present invention relates to treating a tissue in a mammal from the effects of reperfusion using flagellin. .
Cleveland Clinic Foundation


07/02/15
20150182526 

Pyrido[2,3-b]pyrazin-8-substituted compounds and their use


The present invention pertains generally to the field of therapeutic compounds for treating proliferative disorders, cancer, etc., and more specifically to certain pyrido[2,3-b]pyrazin-8-substituted compounds, as described herein, which, inter alia, inhibit raf (e.g., b-raf) activity. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit raf (e.g., braf) activity, to inhibit receptor tyrosine kinase (rtk) activity, to inhibit cell proliferation, and in the treatment of diseases and disorders that are ameliorated by the inhibition of raf, rtk, etc., proliferative disorders such as cancer (e.g., colorectal cancer, melanoma), etc..
Cancer Research Technology Limited


07/02/15
20150182511 

Modulators of aldehyde dehydrogenase activity and methods of use thereof


The present invention provides compounds that function as modulators of aldehyde dehydrogenase activity; and pharmaceutical compositions comprising the compounds. The present invention provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition..
The Board Of Trustees Of The Leland Stanford Junior University


07/02/15
20150182506 

Modulators of aldehyde dehydrogenase and methods of use thereof


The present disclosure provides compounds that function as modulators of aldehyde dehydrogenase (aldh) enzymatic activity, as well as compositions and formulations comprising the compounds. The present disclosure provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition..
The Board Of Trustees Of The Leland Stanford Junior University


07/02/15
20150182443 

Traditional chinese medicine extract composition with whitening skin-care function adn its preparation method


The invention provides a raised white skin rejuvenation medicine composition, wherein said composition comprises the following servings by weight of the composition ratio of raw material: 5 to 10 servings of water, 2 to 5 servings of orchids extract, 2 to 3 servings of winter worm of summer, 2 servings of vitamin-c1, 5 servings of almond oil, 2-3 servings of sucrose laurate, 2-3 servings of oat amino acids, 3-4 servings of hyaluronic acid, 2 to 3 servings of muti pearl, 2 to 3 of pennisetum extract, 2 to 3 servings of white chrysanthemum extract, 2 to 3 servings of white peony extract, 2 to 3 servings of poria extract. The above composition was prepared according to the method of the invention, the composition has activated, whitening, moisturizing super protection function can inhibit the formation of melanin and plant extracts such as angelica restore melanin already formed, the epidermal melanin exclusion dilute huang, make skin white and transparent..
Shang Chen Mei Bang (beijing) Biotechnology Co., Ltd.


07/02/15
20150182432 

Phenyl ketone derivatives as self-tanning agents


The present invention relates to the use of phenyl ketone derivatives of the formula i for use as self-tanning substance or for increasing melanin synthesis, improving melanin transport and/or improving the distribution of melanin in suprabasal layers, and to preparations comprising these phenyl ketone derivatives.. .
Merck Patent Gmbh


07/02/15
20150181910 

Solid animal supplements and methods for making them


The present invention relates to solid animal supplement blocks that have high nutritional values and processes for their manufacture. The solid feed blocks comprise condensed molasses solubles (cms), a source of phosphorous and a liquid source.
A.a. Company Pty Ltd.


07/02/15
20150181798 

Sowing heart control apparatus, sowing heart and single seed drill


A sowing heart control apparatus for controlling a sowing heart with a sowing heart monitoring apparatus having an evaluation unit for determining the occupancy of sowing holes of a rotating seed disk with a seed in operation. The evaluation unit delivers an actual value of the occupancy of one or more sowing holes.
Kverneland As


06/25/15
20150176093 

Methods and systems for processing a reaction product mixture of cellulosic biomass material


Processing of a reaction product mixture of cellulosic biomass material containing at least one volatile organic compound at least one of lignin, a lignin-derived compound, unextracted cellulose, unextracted hemicellulose, a caramelan, and any combination thereof by vaporizing the at least one volatile organic compound using at least thermal energy generated by combusting at least a portion of the reaction product mixture. In a particular embodiment, the reaction product mixture comes from reactions involving deconstruction (or digestion) of cellulosic biomass which contains various polysaccharides (e.g., carbohydrates) and lignin..
Shell Oil Company


06/25/15
20150176072 

Molecular malignancy in melanocytic lesions


Disclosed are methods for determining whether a melanocyte-containing sample (such as a nevus or other pigmented lesion) is benign or a primary melanoma. These methods can include detecting (at the molecular level, e.g., mrna, mirna, or protein) the expression of at least two disclosed genes in a biological sample obtained from a subject.
John Wayne Cancer Institute


06/25/15
20150175871 

Breaker fluid


A breaker fluid composition and methods for using said breaker fluid composition are provided, where the breaker fluid includes a non-aqueous base fluid, a precipitated silica, an acid source, and, in some embodiments, a chelant.. .
M-i, L.l.c.


06/18/15
20150169915 

Active rfid tag with integrated electrical pass-through connection


An active radio frequency identification (rfid) tag is provided that can include an input power connector, an output power connector and a wireless transceiver. The input power connector can be configured to receive an input electrical power signal from an external power source.
The Cleveland Clinic Foundation


06/18/15
20150169914 

Active rfid tag with integrated electrical pass-through connection


An active radio frequency identification (rfid) tag is provided that can include an input power connector, an output power connector and a wireless transceiver. The input power connector can be configured to receive an input electrical power signal from an external power source.
The Cleveland Clinic Foundation


06/18/15
20150169802 

Polymer formation and simulation thereof


A simulation method solves multiple differential equations to estimate concentration, degree of polymerization, and viscosity profiles for thermoset polymer forming reactions. For foam-forming reactions, the blowing agent evaporation to form foam cells is estimated.
Homeland Technologies Research, Llc


06/18/15
20150168570 

Spectral imaging system and method


Spectral x-ray imaging using a photon counting x-ray detector (pcxd) transmits a broad spectrum x-ray beam through an object, detects the transmitted x-ray beam with the pcxd and processes the detected signals to determine material characteristics of the object using both the detected signals as a function of detector layer and the detected signals as a function of the particular energy band. Each detector layer of the multiple detector layers produces at least two signals, each signal representing a detected x-ray intensity in a particular energy band, and the depth information contained in the separate read-out channels..
The Board Of Trustees Of The Leland Stanford Junior University


06/18/15
20150168419 

Prediction of a small-for-gestational age (sga) infant


A method of predicting a sga infant in a patient at a pre-symptomatic gestational stage is described. The method comprises a step of assaying a biological sample from the patient for an abundance of a plurality of metabolite biomarkers selected from the 19 metabolite biomarkers of table iv, correlating the abundance of the plurality of metabolite biomarkers with a metabolite fingerprint of sga shown in table iv, and predicting sga based on the level of correlation between the abundance of the plurality of metabolite biomarkers and the metabolite fingerprint of table iv..
University College Cork - National University Of Ireland, Cork


06/18/15
20150168236 

Surface area-based pressure sensing


Various aspects of the instant disclosure relate to pressure sensing methods and apparatuses. As may be implemented in accordance with one or more embodiments, an apparatus includes a plurality of structures having respective surface areas that are implemented to contact at least one of an electrode and other ones of the structures.
The Board Of Trustees Of The Leland Stanford Junior University


06/18/15
20150167048 

Beta-lactamase substrates and methods of their use for the diagnosis of tuberculosis


β-lactamase substrates and methods for using the substrates to detect β-lactamase diagnose tuberculosis.. .
The Board Of Trustees Of The Leland Stanford Junior University


06/18/15
20150166646 

Methods and compositions for treating or diagnosing melanoma


Methods and compositions are provided for treating melanoma in a mammalian subject by reducing, inhibiting or down-regulating tumor-associated macrophage (tam) production or activity in the subject. The methods can involve a combination of reducing macrophage production and number while administering an anti-cancer therapy.
The Wistar Institute Of Anatomy And Biology


06/18/15
20150166532 

Host targeted inhibitors of dengue virus and other viruses


Novel antiviral compounds of formulae (i)-(iii) are provided: (i) (ii) (iii) the inventive compounds, pharmaceutical compositions thereof, and kits including the inventive compounds are useful for the prevention and treatment of infectious diseases caused by viruses, for example, by flaviviridae virus (e.g., dengue virus (deny)), kunjin virus, japanese encephalitis virus, vesicular stomatitis virus (vsv), herpes simplex virus 1 (hsv-1), human cytomegalovirus (hcmv), poliovirus, junin virus, ebola virus, marburg virus (marv), lassa fever virus (lasv), venezuelan equine encephalitis virus (veev), or rift valley fever virus (rvfv).. .
Dana-farber Cancer Institute, Inc.


06/18/15
20150165519 

Shaped parts made from corrosion-resistant copper alloys


The invention relates to metal formed parts, a method for producing the formed parts, use of the formed parts and the use of alloys to produce formed parts. Formed parts are produced from copper alloys with the composition (percent by weight) sn: 2 to 8%, zn: 2.5 to 13%, pb: less than 0.25%, ni: maximum 0.6%, optionally phosphorous, remainder cu, but at least 84%, and unavoidable impurities, wherein the production of the formed parts includes at least one hot pressing process.
Wieland-werke Ag


06/18/15
20150165419 

Hydrogenation catalysts with cobalt-modified supports


The present invention relates to catalysts, to processes for making catalysts and to chemical processes employing such catalysts. The catalysts are preferably used for converting acetic acid to ethanol.
Celanese International Corporation


06/18/15
20150165227 

Light-activated cation channel and uses thereof


The present invention provides compositions and methods for light-activated cation channel proteins and their uses within cell membranes and subcellular regions. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-activated cation channels to specific cells or defined cell populations.
The Board Of Trustees Of The Leland Stanford Junior University


06/18/15
20150164896 

Targeting a non-canonical notch signaling pathway for cancer treatment


Methods and compositions are provided for treating an individual having cancer. Aspects of the methods include administering to the individual an inhibitor of a non-canonical notch signaling pathway gene in an amount effective to treat the cancer.
The Board Of Trustees Of The Leland Stanford Junior University


06/18/15
20150164872 

Histone demethylase inhibitors


Provided herein are substituted pyrazolylpyridine, pyrazolylpyridazine, and pyrazolylpyrimidine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase.
Quanticel Pharmaceuticals, Inc.


06/18/15
20150164850 

Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy


In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.. .
Amarin Pharmaceuticals Ireland Limited


06/18/15
20150164648 

Low profile mobile/fixed prosthetic knee systems


A knee prosthesis system has a tibial component with frame with medial and lateral openings to receive the medial and lateral bearing components. The bearing components have distal surfaces that are exposed when assembled with the frame and pegs extending distally from the distal surfaces.
Deputy (ireland)


06/18/15
20150164645 

Orthopaedic tibial prosthesis having tibial augments


A tibial orthopaedic prosthesis assembly for use during performance of a knee replacement procedure includes one or more tibial augments configured to be coupled to a tibial tray. Each tibial augment includes an exterior side surface of varying angulation relative to a top surface of the tibial augment..
Depuy (ireland)


06/18/15
20150164562 

Surgical instruments


A kit of parts for inserting a deformable implant into a cavity in a bone of a patient is described. An inserter instrument (1) comprises a body (100) having a cavity extending along a longitudinal axis from a distal end to a proximal end.
Depuy (ireland)


06/18/15
20150164520 

Apparatus and providing a reference indication to a patient tissue


An apparatus for providing a reference indication to a patient tissue includes a primary locating block having a patient-specific primary mating surface contoured for mating contact with a portion of the patient tissue in a predetermined primary mating orientation custom-configured responsive to preoperative imaging of the patient tissue. At least one mounting feature is provided to the primary locating block.
The Cleveland Clinic Foundation


06/18/15
20150164519 

Devices and methods for treating medical conditions associated with sacroiliac joint abnormalities


Device and methods for treating conditions caused by or associated with a sacroiliac joint abnormality using radiofrequency ablation. A surgical jig is provided that facilitates safe, easy, and quick placement of electrodes in a patient's spinal region for radiofrequency ablation of a set of spinal nerves and/or sacroiliac ligaments..
The Cleveland Clinic Foundation


06/18/15
20150164121 

Food supplement composition


A dietary supplement for promoting increased vitality, supporting mood, improving heart health, improving immune strength, improving antioxidant balance, protecting against free radical damage, improving bowel function, and enhancing flavonoid intake. The dietary supplement is a combination of cacao, chia seeds, goji berries, and maca root.
Homeland Housewares, Llc


06/11/15
20150159225 

Uveal melanoma prognosis


Methods and kits for monitoring or providing a prognosis for a subject having uveal melanoma are described. The methods include obtaining a biological sample from the subject, determining the expression level of one or more uveal melanoma-associated mirs and/or mir biogenesis factors in the biological sample, and characterizing the subject as high risk if one or more uveal melanoma-associated mirs and/or mir biogenesis factors are differentially expressed as compared with a corresponding control..
The Cleveland Clinic Foundation


06/11/15
20150157879 

Radiation therapy device for ocular melanoma


The present invention advantageously provides a method and system for providing accurately localized, non-invasive radiation treatment for ocular melanoma or other intraocular indications through the completion of specified research tasks. The present invention further provides for dynamic localization of tumors associated with such indications.
University Of Miami


06/11/15
20150157747 

Compounds with reduced ring size for use in diagnosing and treating melanoma, including metastatic melanoma and methods related to same


The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention.
Stc.unm


06/04/15
20150152139 

Peptide tyrosinase activators


Peptides that increase melanin synthesis are provided. These peptides include pentapeptides ysswy, yrsrk, and their variants.
Escape Therapeutics, Inc.




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