Follow us on Twitter
twitter icon@FreshPatents


Elan patents

      

This page is updated frequently with new Elan-related patent applications.




 Electrochemical cell with melanin electrode patent thumbnailnew patent Electrochemical cell with melanin electrode
An electrochemical cell includes an anode configured to produce multivalent cations during a discharge process, and a cathode comprising a catechol-bearing melanin. The cathode is configured to reversibly oxidize a catechol of the catechol-bearing melanin into a quinone by an extraction of the multivalent cation during a recharge process and reduce the quinone to the catechol by an insertion of the multivalent cation during the discharge process.
Carnegie Mellon University


 Dual targeting antisense oligonucleotides as apoptotic inhibtor therapeutic compostions and methods for their use in the treatment of cancer patent thumbnailnew patent Dual targeting antisense oligonucleotides as apoptotic inhibtor therapeutic compostions and methods for their use in the treatment of cancer
Provided herein are compositions, method and uses for modulating iap activity or for the treatment of cancer. The compositions comprise dual-targeting antisense oligonucleotides (daso) for administration to a cancer cell, wherein the cancer cell may be characterized by elevated expression of one of more of birc6, ciap1 or survivin.

 6-aryl-4-phenylamino-quinazoline analogs as phosphoinositide-3-kinase inhibitors patent thumbnailnew patent 6-aryl-4-phenylamino-quinazoline analogs as phosphoinositide-3-kinase inhibitors
The present invention relates to 6-aryl-4-phenylamino quinazolines of formula i wherein, r and r″ are as herein described. The present invention particularly relates to synthesis and anticancer and phoshpoinositide-3-kinase-α (pi3k-α) inhibitory activity.
Council Of Scientific & Industrial Research


 Induction of thyroid iodide-handling gene expression in human cancers patent thumbnailnew patent Induction of thyroid iodide-handling gene expression in human cancers
Dual suppression of the map kinase and pi3k/akt pathways showed synergistic or greatly enhanced anti-melanoma cell effects, compared to suppression of a single pathway, including the inhibition of cell proliferation, transformation and invasion, induction of g0/g1 cell cycle arrest and, importantly, cell apoptosis. Remarkably, suppression of either pathway induces the expression of thyroid iodide-handling genes and dual suppression of the two pathways synergistically and robustly induces expression of these genes, accompanied by uptake of radioiodine in the cells.
The Johns Hopkins University


 Zeaxanthin for tumor treatment patent thumbnailnew patent Zeaxanthin for tumor treatment
A composition comprising a pharmaceutically effective amount of zeaxanthin or its derivative for use in treating a malignant tumor and a method of using a pharmaceutically effective amount of zeaxanthin or its derivative either alone or together with one or more pharmaceutical agents for treating a malignant tumor. The tumor may be, but is not limited to breast cancer, cervix cancer, colon cancer, cutaneous melanoma, cutaneous squamous carcinoma, hepatocellular carcinoma, lung cancer, osteosarcoma, prostate cancer, and uveal melanoma.
The New York Eye And Ear Infirmary


 Composition comprising extract of alpine wormwood patent thumbnailnew patent Composition comprising extract of alpine wormwood
Disclosed is a composition containing an extract of alpine wormwood (artemisia umbelliformis) as an active ingredient. The composition disclosed in the present specification has the effect of reducing melanin generation, or inhibiting activation of tyrosinase due to the composition containing the extract of an alpine wormwood (artemisia umbelliformis).
Amorepacific Corporation


 Anti-metalloprotease antibody for diagnosis and treatment of cancers patent thumbnailAnti-metalloprotease antibody for diagnosis and treatment of cancers
Expression of proteolytically active, high molecular weight adam protease is relatively increased in tumour cells that also express the putative tumour stem cell marker cd133. An antibody or antibody fragment such as 8c7 monoclonal antibody may be used to selectively bind to proteolytically active, high molecular weight adam10 protease to thereby detect tumour cells and also as a therapeutic agent for treating cancers, tumours and other malignancies inclusive of leukemia, lymphoma, lung cancer, colon cancer, adenoma, neuroblastoma, brain tumour, renal tumour, prostate cancer, sarcoma and/or melanoma..
Ludwig Institute For Cancer Research Ltd


 Melanocortin-1 receptor-specific cyclic hexapeptides patent thumbnailMelanocortin-1 receptor-specific cyclic hexapeptides
Where r1, r2, r3, r4, r5, r6, r7, r8 and r9 are as defined in the claims, compositions and formulations including the hexapeptides of the foregoing formula or salts thereof, and methods of preventing, ameliorating or treating melanocortin-1 receptor-mediated or responsive diseases, indications, conditions and syndromes.. .

 Methods and compositions for gene delivery to on bipolar cells patent thumbnailMethods and compositions for gene delivery to on bipolar cells
Disclosed are capsid-modified raav expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations that include them. Also disclosed are methods of preparing and using novel capsid-protein-mutated raav vector constructs in a variety of diagnostic and therapeutic applications including, inter alia, as delivery agents for diagnosis, treatment, or amelioration of one or more diseases, disorders, or dysfunctions of the mammalian eye.
University Of Florida Research Foundation, Inc.


 Compositions for affecting weight loss patent thumbnailCompositions for affecting weight loss
Disclosed are compositions for affecting weight loss comprising a first compound and a second compound, where the first compound is an opioid antagonist and the second compound causes increased agonism of a melanocortin 3 receptor (mc3-r) or a melanocortin 4 receptor (mc4-r) compared to normal physiological conditions. Also disclosed are methods of affecting weight loss, increasing energy expenditure, increasing satiety in an individual, or suppressing the appetite of an individual, comprising identifying an individual in need thereof and treating that individual to antagonize opioid receptor activity and to enhance α-msh activity..
Orexigen Therapeutics, Inc.


Composition

The present invention relates to an oxidatively curable coating composition with which a formulation for use in catalysing the curing of oxidatively curable coating compositions, in particular oxidatively curable coating compositions comprising an oxidatively curable alkyd-based resin, has been contacted. The formulations described herein comprise a triazacyclononane-based chelant; a manganese (ii), (iii) or (iv) salt; and an alcohol or ketone, which alcohol or ketone typically acts as a solvent for the salt and the chelant.
Catexel Limited

Prognostic and diagnostic kits and herbal therapies for treating skin conditions, autoimmune diseases, inflammatory ailments and cancer

A treatment regimen for psoriasis, eczema or other skin ailment, inflammation, autoimmune disease, leukemia, melanoma or other cancer includes administering to a patient a known or discovered treatment regimen along with periodic doses of an herbal combination including sheng di huang, da huang or jin yin hua or combinations thereof.. .
Sirbal Ltd.

Prognostic and diagnostic methods and herbal therapies for treating skin conditions, autoimmune diseases, inflammatory ailments and cancer

A treatment regimen for psoriasis, eczema or other skin ailment, inflammation, autoimmune disease, leukemia, melanoma or other cancer includes administering to a patient a known or discovered treatment regimen along with periodic doses of an herbal combination including sheng di huang, da huang or jin yin hua or combinations thereof.. .
Sirbal Ltd.

Composition containing fucosterol for skin whitening or moisturizing

The present invention relates to a novel use of fucosterol and, more specifically, to a composition for skin whitening or composition for skin moisturizing, which is characterized by containing fucosterol. Fucosterol of chemical formula 1 below has an excellent whitening effect of inhibiting melanin generation and tyrosinase activity, and thus can be used as an active ingredient of a cosmetic composition for whitening, a food composition, or a pharmaceutical composition.
Industry-academic Cooperation Foundation, Yonsei University

Lithographic measuring overlay error and a device manufacturing method

A lithographic apparatus including an inspection apparatus can measure the overlay error of a target in a scribelane is measured. The overlay error of the required feature in the chip area may differ from this due to, for example, different responses to the exposure process.
Asml Netherlands B.v.

Armet as a marker for cancer

Disclosed is a method aiding in the assessment of cancer. More specifically disclosed is the use of the arginine-rich metastasized in early tumors protein (=armet) as a universal marker of different cancer types.
Roche Diagnostics Operations, Inc.

Genetically stable oncolytic rna virus, manufacturing and use thereof

In a method for manufacturing a modified enterovirus of echo 7 type by modification of native echo 7 virus, isolated by a known method from human feces and identified by genome sequence, the modification is performed initially conducting the virus adaptation in cancer cells, attenuated by anti-cancer agent dacarbazine, further passaging the modified virus in human embryonal fibroblast culture, followed by propagation in human melanoma cells and further passaging in human embryonal fibroblast culture, that was treated by ribavirin, isolation and purification by known method. The modified virus is suitable for treating various tumours..
Ditesan Ltd

Csgp4 - specific chimeric antigen receptor for cancer

Embodiments of the disclosure include methods and compositions related to chimeric antigen receptors (car) that target chondroitin sulfate proteoglycan-4 (cspg4). T cells transduced with a cspg4-specific car are effective for inhibition of particular cancer cells that express cspg4.
Baylor College Of Medicine

Pulverulent semisynthetic material obtained by modifying the composition of a natural marine biomaterial, manufacture thereof, and applications thereof

A pulverulent semisynthetic material, derived from a natural marine biomaterial, namely the aragonitic inner layer of the shell of bivalve molluscs selected from the group including pinctadines, notably pinctada maxima, margaritifera, and tridacnes, notably tridacnagigas, maxima, derasa, tevaroa, squamosa, crocea, hippopushippopus, hippopusporcelanus, in pulverulent form, with addition of insoluble and soluble biopolymers and calcium carbonate transformed by carbonation; it also relates to the method of preparation thereof and to the uses thereof.. .
Mega Industrie

Compounds for use in diagnosing and treating melanoma, including metastatic melanoma and methods related to same

The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a msh receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers.
Stc.unm

Method for treating stage iv melanoma

The present invention relates to a method of treating stage iv melanoma in a subject. The method includes the step of administering to the subject a therapeutically effective amount of a melanoma cell lysate and/or an immunotherapeutic extract, component or antigen thereof..

Methods for treatment of hair graying

The invention relates to methods for treating hair graying. More specifically, the present invention discloses new methods for reducing, stopping and/or reversing of hair graying in mammals by stimulating stem cell migration to produce or stimulate melanocytes in hair follicles.
Stemtech International, Inc.

Plant extract composition for skin whitening and reducing melanin as well as application thereof

Provided are a plant extract composition and a pharmaceutical composition for inhibiting tyrosinase activity, preventing melanogenesis or treating melanogenesis, wherein the plant extract composition contains curcumin and resveratrol by weight ratio from 4:1 to 1:4. The plant extract composition and the pharmaceutical composition are useful for preventing and treating pigmentation for skin whitening, and achieve the effect of whitening skin and reducing pigmentation for a subject in topical site..
Caliway Biopharmaceuticals Co., Ltd.

Diagnostic radio frequency identification sensors and applications thereof

An integrated passive wireless chip diagnostic sensor system is described that can be interrogated remotely with a wireless device such as a modified cell phone incorporating multi-protocol rfid reader capabilities (such as the emerging gen-2 standard) or bluetooth, providing universal easy to use, low cost and immediate quantitative analyses, geolocation and sensor networking capabilities to users of the technology. The present invention can be integrated into various diagnostic platforms and is applicable for use with low power sensors such as thin films, mems, electrochemical, thermal, resistive, nano or microfluidic sensor technologies.
Altivera, Llc

Liquid crystal panel and liquid crystal display

The present invention discloses a liquid crystal paneland a liquid crystal display. The liquid crystal panel comprises: a first substrate; a second substrate, which is arranged opposite to the first substrate; a liquid crystal layer, which is provided between the first substrate and the second substrate and comprises multiple liquid crystal molecules; an electrode structure, which is arranged on the first substrate or the second substrate, and an electric field is generated in the liquid crystal layer by voltage control, so that the liquid crystal molecule deflects under the effects of the electric field; wherein, the liquid crystal molecule comprises a positive liquid crystal molecule and a negative liquid crystal molecule, the first substrate and the second substrate are divided into multiple pixel regions, each pixel region is further divided into at least two sub-pixel regions, the different sub-pixels in the same pixel region correspond to the liquid crystal molecules with different initial orientations or electrode structures.
Shenzhen China Star Optoelectronics Technology Co., Ltd.

Detection of chromosomal region copy number changes to diagnose melanoma

This invention provides methods of detecting melanoma. The methods comprises detecting a gain or loss of certain chromosomal regions that undergo copy number changes in melanoma..
The Regents Of The University Of California

Melanocortin receptor ligands

And pharmaceutically-acceptable salts thereof that act as ligands for one or more of the melanocortin receptors, to methods of using such compounds to treat mammals and to pharmaceutical compositions comprising said compounds.. .

Treatment of pd-l1-positive melanoma using an anti-pd-1 antibody

The invention provides a method of treating a melanoma comprising (i) identifying a patient having a pd-l1 positive melanoma and (ii) administering to the patient an anti-pd-1 antibody or an antigen-binding portion thereof (“an anti-pd-1 antibody monotherapy”). The methods of the invention can extend progression-free survival for over 12 months and/or reduces the tumor size at least about 10%, about 20%, about 30%, about 40%, or about 50% compared to the tumor size prior to the administration..
Bristol-myers Squibb Company



Elan topics:
  • Folic Acid
  • Carbon Dioxide
  • Antibodies
  • Immune Response
  • High Energy
  • Inorganic Compounds
  • Electrolysis
  • Semiconductor Material
  • Semiconductor
  • Hydrogen Production From Water
  • Female Sexual Dysfunction
  • Dysfunction
  • Sexual Dysfunction
  • Mammography
  • Radiograph


  • Follow us on Twitter
    twitter icon@FreshPatents

    ###

    This listing is a sample listing of patent applications related to Elan for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Elan with additional patents listed. Browse our RSS directory or Search for other possible listings.


    0.7515

    file did exist - 2154

    1 - 1 - 51