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Elan

Elan-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Assessing retinal pigment epithelial cell populations
Cell Cure Neurosciences Ltd.
January 11, 2018 - N°20180011092

A method of qualifying whether a cell population is a suitable therapeutic for treating an eye condition is disclosed. The method comprises analyzing co-expression of premelanosome protein (pmel17) and at least one polypeptide selected from the group consisting of cellular retinaldehyde binding protein (cralbp), lecithin retinol acyltransferase (lrat) and sex determining region y-box 9 (sox 9) in the population of cells.
Antibodies against p97 and conjugates thereof
Bioasis Technologies, Inc.
January 11, 2018 - N°20180009898

Provided are conjugates between (a) an antibody or antigen-binding fragment thereof that binds to p97 (melanotransferrin; mtf) and (b) an agent of interest, and related compositions and methods, for example, to improve pharmacokinetics and/or delivery of the agent of interest across the blood-brain barrier (bbb) and into tissues of the central nervous system (cns).
Therapy for vitiligo
Clinuvel Pharmaceuticals Limited
January 11, 2018 - N°20180008676

The present invention relates to a therapy for vitiligo. In particular the present invention provides a pharmaceutical composition comprising an alpha melanocyte stimulating hormone (alpha-msh) analogue either alone, in combination with narrow band uvb and/or in combination with one or more corticosteroids, immunosuppressants, anti-inflammatory agents and/or photochemotherapeutic agents for the treatment or prevention of vitiligo.
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Herbicidal compositions comprising oxyfluorfen and haloxyfop
Dow Agrosciences Llc
January 11, 2018 - N°20180007899

An herbicidal composition containing (a) oxyfluorfen and (b) haloxyfop or an agriculturally acceptable ester or salt thereof provides control of undesirable vegetation, e. G., in crops, including but not limited to direct-seeded, water-seeded and transplanted rice, wheat, barley, oats, rye, sorghum, corn/maize, cotton, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, including, but not limited to, citrus, grapes ...
Non-streaking durable composition for cleaning and disinfecting hard surfaces
Ecolab Usa Inc.
January 11, 2018 - N°20180007895

The present invention relates to quaternary ammonium disinfecting cleaning compositions comprising a quaternary ammonium compound, an alkyl a polyglycoside with a cmc greater than 1000 ppm and a chelant. Beneficially, the compositions provide residual sanitizing efficacy without diminished performance and without scale formation when diluted with hard water. The compositions are suitable for inactivating and/or reducing infectious agents, particularly norovirus, ...
Anti human interleukin-1 receptor accessory protein (il1 rap) antibodies and uses thereof
Cantargia Ab
January 04, 2018 - N°20180002430

The present invention provides an antibody or an antigen-binding fragment thereof with binding specificity for human interleukin-1 receptor accessory protein (il1rap) wherein the antibody or antigen-binding fragment is capable of inhibiting the binding of antibody ‘can04’ to human il1rap. The invention further provides the use of such antibodies or an antigen-binding fragments in the treatment and/...
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Therapeutic target for the treatment of cancers and related therapies and methods
The Children's Medical Center Corporation
January 04, 2018 - N°20180000767

Disclosed herein are compositions and methods for treating or preventing certain cancers in a subject. In certain embodiments such compositions and methods generally relate to the use of g-coupled protein receptor 40 (gpr40) agonists to inhibit the growth or induce apoptosis of certain cancer cells. The compositions and related methods disclosed herein may be used to treat subjects affected by cancers, ...
A skin lightening composition comprising niacinamide and ilomastat
Conopco, Inc., D/b/a Unilever
January 04, 2018 - N°20180000719

The present invention is in the field of personal care compositions; in particular skin lightening compositions. A composition that combines the cyclic adenylic acid reduction and the reduction of melanin content in melanocytes remains to be desired. It has been found that niacinamide in combination with mmp inhibitor galardin synergistically reduces melanin content in melanocytes. The invention thus relates to ...
Hair care compositions for calcium chelation
The Procter & Gamble Company
January 04, 2018 - N°20180000715

A hair care composition that removes calcium fatty carboxylate salts from the hair and scalp is provided. The hair care composition includes a calcium chelant, an anionic surfactant, a hydrotrope, a carrier, and optionally a zwitterionic surfactant.
Conditioner composition comprising a chelant
The Procter & Gamble Company
January 04, 2018 - N°20180000714

Described herein is a hair conditioner composition and methods of using the same, the hair conditioner composition including an effective chelant. The hair conditioner composition further includes one or more high melting point fatty compounds and a cationic surfactant.
Shampoo compositions comprising a chelant
The Procter & Gamble Company
January 04, 2018 - N°20180000713

Described herein is a shampoo composition and methods of using the same, the shampoo composition including a class i and/or class ii chelant, a detersive surfactant, and a carrier.
Conditioner composition comprising a chelant
The Procter & Gamble Company
January 04, 2018 - N°20180000706

Described herein is a hair conditioner composition and methods of using the same, the hair conditioner composition including an effective chelant. The hair conditioner composition further includes one or more high melting point fatty compounds and a cationic surfactant.
Shampoo compositions comprising a chelant
The Procter & Gamble Company
January 04, 2018 - N°20180000705

Described herein is a shampoo composition and methods of using the same, the shampoo composition including a copper chelant, a detersive surfactant, and a carrier.
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Rapid quantitative detection of single nucleotide polymorphisms or somatic variants and methods to identify malignant ...
The General Hospital Corporation
December 28, 2017 - N°20170369939

Provided are systems, kits, and methods for the quantitative detection of single nucleotide polymorphisms or variants to identify malignant neoplasms. The methods include use of modified oligonucleotide blockers with peptide nucleic acid backbones that hybridize to and block logarithmic amplification of the wild-type alleles of a target, and incorporation of locked nucleic acids into probes that are complementary to a ...
Formulations and methods for mineral scale removal
Fqe Chemicals Inc.
December 28, 2017 - N°20170369764

A composition is provided for sulfate scale removal, said composition comprising one or more chelants and one or more accelerants, wherein said accelerants serve to occupy reactive sites of cations of the sulfate scale. The composition is preferably provided wherein said one or more chelants comprise a mixture of two or more polyaminopolycarboxylic acids. The composition if further preferably provided, ...
Selective histone deactylase 6 inhibitors
Board Of Trustees Of The University Of Illinois
December 28, 2017 - N°20170369428

Disclosed are selective histone deactylase inhibitors (hdaci) that having formula i. Methods of making and using these inhibitors for the treatment of cancer, in particular melanoma are also disclosed.
Use of anti-pd-1 antibody in combination with anti-cd27 antibody in cancer treatment
Celldex Therapeutics, Inc.
December 28, 2017 - N°20170368172

This disclosure provides methods for treating cancer in a subject comprising administering to the subject an anti-pd-1 antibody and an anti-cd27 antibody. In some embodiments, the cancer is colorectal cancer, rectal cancer, colon cancer, lung cancer, melanoma, ovarian cancer, head and neck cancer, or any combination thereof.
Identifying service providers as freelance market participants
Linkedin Corporation
December 21, 2017 - N°20170365012

A system, a machine-readable storage medium storing instructions, and a computer-implemented method are described herein for a classification engine for identifying, according to encoded rules of a plurality of service models, at least one type of service offered by a target member account of a social network service. The classification engine classifies, according to encoded rules of a freelancer inference ...
Methods and materials for treating cancer
Mayo Foundation For Medical Education And Research
December 21, 2017 - N°20170362595

This document provides methods and materials for treating cancers including renal cancer (e. G., renal cell carcinoma) as well as ovarian, breast, prostate, colon, pancreatic, bladder, liver, lung, and thyroid cancers and melanoma. For example, methods and material for using one or more inhibitors of an scd1 polypeptide to treat renal cell carcinoma (e. G., clear cell renal cell carcinoma (...
Tem-1 diagnostic antibodies
Morphotek, Inc.
December 21, 2017 - N°20170362335

Described herein are anybodies, and antigen-binding fragments thereof, that are specific for tumor endothelial marker 1 (tem-1), related polynucleotides, expression vectors, and cells that express the described antibodies. Also provided are methods of using the described antibodies, and antigen-binding fragments thereof, and related kits. Provided herein are also methods for diagnosing tem-1-expressing cancers (such as melanoma, sarcoma, bladder cancer or ...
Gpc3 epitope peptides for th1 cells and vaccines containing the same
Oncotherapy Science, Inc.
December 21, 2017 - N°20170362287

Isolated gpc3-derived epitope peptides having th1 cell inducibility are disclosed herein. Such peptides can be recognized by mhc class ii molecules and induce th1 cells. In preferred embodiments, such a peptide of the present invention can promiscuously bind to mhc class ii molecules and induce gpc3-specific cytotoxic t lymphocytes (ctls) in addition to th1 cells. Such peptides are ...
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