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Elan patents



      
           
This page is updated frequently with new Elan-related patent applications. Subscribe to the Elan RSS feed to automatically get the update: related Elan RSS feeds. RSS updates for this page: Elan RSS RSS


Date/App# patent app List of recent Elan-related patents
11/20/14
20140343071
 Compositions and methods for treating cancer patent thumbnailnew patent Compositions and methods for treating cancer
The instant invention provides a method of treating a cancer, selected from the group consisting of breast cancer, melanoma, colorectal cancer, non-small cell lung cancer and ovarian cancer, by administering a combination of a wee1 inhibitor and a chk1 inhibitor, wherein the wee1 inhibitor is mk-1775 or a pharmaceutically acceptable salt thereof, or mk-3652 or a pharmaceutically acceptable salt thereof, and the chk1 inhibitor is mk-8776 or a pharmaceutically acceptable salt thereof, or sch900444 or a pharmaceutically acceptable salt thereof.. .
11/20/14
20140341971
 Composition for targeting dendritic cells patent thumbnailnew patent Composition for targeting dendritic cells
The present invention relates to a composition for targeting dendritic cells. In particular, the present invention relates to a composition comprising: a) one or more antigens; b) an anti-dc-sign immunoglobulin single variable domain; and c) a carrier which carries a) and b).
11/20/14
20140341916
 Therapeutic combinations and methods of treating melanoma patent thumbnailnew patent Therapeutic combinations and methods of treating melanoma
The invention provides therapeutic combinations of anti-etbr antibodies and map kinase inhibitors and methods of using the same to treat melanoma.. .
11/13/14
20140336371
 Sirna molecule for inhibiting growth of melanin and application thereof patent thumbnailSirna molecule for inhibiting growth of melanin and application thereof
Provided is a double-chain sirna molecule targeting a microphthalmia-associated transcription factor mitf coding gene. A sense strand of the sirna molecule has a sequence of seq id no: 3 and an anti-sense strand has a sequence of seq id no: 4, and the anti-sense strand specifically binds to mrna of the mitf coding gene, to degrade the mrna, thereby reducing the systhesis of melanin.
11/13/14
20140336138
 Compositions and methods for screening and treatment of sturge-weber syndrome, klippel-trenaunay-weber syndrome, and port-wine stains (pwss) patent thumbnailCompositions and methods for screening and treatment of sturge-weber syndrome, klippel-trenaunay-weber syndrome, and port-wine stains (pwss)
Compositions and methods for treatment of sturge-weber syndrome, klippel-trenaunay-weber syndrome, port-wine stains and related neurocutaneous disorders are provided. Cell lines having the somatic mutation gnaq p.arg183gln amino acid substitution, which was found to be the cause of port-wine stains (prevalence 1 in 300) and sturge-weber syndrome are also provided.
11/13/14
20140336089
 Scale inhibitor patent thumbnailScale inhibitor
This invention relates to a process for inhibiting scaling in a subterranean oil or gas producing formation, comprising adding to the formation a composition comprising a metal chelant, a scale inhibitor and divalent metal cations, wherein the stability constant of the metal chelant—metal cation chelate at ambient temperature is equal to or higher than the stability constant of the chelate formed from the metal cations and the scale inhibitor, and wherein the solubility of the chelate formed from the metal cations and the scale inhibitor decreases with increasing temperature.. .
11/06/14
20140329743
 Method of treating melanocortin-4 receptor-associated disorders in heterozygous carriers patent thumbnailMethod of treating melanocortin-4 receptor-associated disorders in heterozygous carriers
A method of treating a disorder in a subject. The method comprises administering to said subject an effective amount of an agonist of the melanocortin-4 receptor (mc4r).
11/06/14
20140328775
 Cosmetic compositions and methods for inhibiting melanin synthesis patent thumbnailCosmetic compositions and methods for inhibiting melanin synthesis
A cosmetic composition suitable for topical application, for example, is provided. In some examples, the cosmetic composition may include batyl alcohol, undecylenoyl phenylalanine, hexyldecanol, and bisabolol.
11/06/14
20140327967
 Methods, systems, and apparatus for reducing the frequency and/or severity of photophobic responses or for modulating circadian cycles patent thumbnailMethods, systems, and apparatus for reducing the frequency and/or severity of photophobic responses or for modulating circadian cycles
An optical filter may reduce the frequency and/or severity of photophobic responses or for modulating circadian cycles by controlling light exposure to cells in the human eye in certain wavelengths, such as 480 nm and 590 nm, and a visual spectral response of the human eye. The optical filter may disrupt the isomerization of melanopsin in the human eye reducing the availability of the active isoform, whereas the attenuation of light weighted across the action potential spectrum of the active isoform attenuates the phototransduction cascade leading to photophobic responses.
10/30/14
20140323950
 Skin lightener in phototherapy patent thumbnailSkin lightener in phototherapy
The invention relates, inter alia, to melanin synthesis inhibitors for use in treating skin illnesses, wherein the skin is additionally irradiated with an artificial radiation source. The invention further relates to cosmetic treatments..
10/30/14
20140323298
Herbicidal compositions comprising oxyfluorfen and haloxyfop
An herbicidal composition containing (a) oxyfluorfen and (b) haloxyfop or an agriculturally acceptable ester or salt thereof provides control of undesirable vegetation, e.g., in crops, including but not limited to direct-seeded, water-seeded and transplanted rice, wheat, barley, oats, rye, sorghum, corn/maize, cotton, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, including, but not limited to, citrus, grapes and tree nuts, aquatics, vegetables (e.g., onions, shallots, peppers, tomatoes, artichokes, cole crops, guava, papaya and strawberries), industrial vegetation management, deciduous trees, conifers, perennial crops and plantation crops (including, but not limited to, coffee and palm oil) and rights of way.. .
10/30/14
20140322810
Natural and synthetic compounds for treating cancer and other diseases
This invention provides a method of synthesizing new active compounds for pharmaceutical uses including cancer treatment, wherein the cancers comprise breast, leukocytic, liver, ovarian, bladder, prostatic, skin, bone, brain, leukemia, lung, colon, cns, melanoma, renal, cervical, esophageal, testicular, spleenic, kidney, lymphatic, pancreatic, stomach and thyroid cancers. This invention is an anti-adhesion therapy which uses the compound as a mediator or inhibitor of adhesion proteins and angiopoietins.
10/30/14
20140322246
Ige anti-hmw-maa antibody
In one aspect, there is provided an antibody or a functional fragment thereof, wherein the antibody or functional fragment thereof is capable of binding specifically to high molecular weight melanoma associated antigen (hmw-maa), and binding to an fcε receptor.. .
10/30/14
20140322132
Fragments of p97 and uses thereof
Provided are fragments of human p97 (melanotransferrin) polypeptides having blood-brain barrier (bbb) transport activity, including variants and combinations thereof, conjugates comprising said p97 fragments, and related methods of use thereof, for instance, to facilitate delivery of therapeutic or diagnostic agents across the bbb.. .
10/23/14
20140316106
Integrin-blocking polypeptides and uses thereof
A series of integrin blockers that present strong angiogenesis inhibiting performance, high integrin affinity and integrin-bonding capacity is provided. This series of integrin blockers can be adopted in treatment of solid tumors and rheumatoid arthritis.
10/23/14
20140314814
Antigen presenting cancer vaccine
The disclosure provides reagents, methods, and kits, for treating melanoma. The reagent encompasses interferon-gamma (ifn-gamma) responsive melanoma cells, where the cells are autophagic and non-apoptotic melanoma cells, and where the cells express mhc class if.
10/23/14
20140314810
Compositions containing purine and pyrimidine nucleosides, peptides, and manganese and their uses
The invention provides methods of producing vaccines directed against methicillin-resistant staphylococcus aureus (mrsa) or venezuelan equine encephalitis virus (veev), with the methods comprising culturing, harvesting and/or suspending the mrsa or veev in the presence of a radiation-protective composition and irradiating the mrsa with a dose of radiation sufficient to render the mrsa or veev replication-deficient and/or non-infective. The radiation-protective compositions used in the methods of the present invention comprise at least one nucleoside, at least one antioxidant and at least one small peptide..
10/23/14
20140314799
Methods, agents and peptides for inhibiting matrix metalloproteinase-2 signaling
Screening assays and methods of using same for screening to identify modulator agents or compounds that affect matrix metalloproteinase-2 (mmp-2) mediated activation of toll-like receptor-2 (tlr-2) are described herein. Pharmaceutical and immunogenic compositions comprising agents or compounds that modulate mmp-2 mediated activation of tlr-2 are also encompassed.
10/23/14
20140314697
Method for inhibiting inflammation and reducing melanophilin expression with glycine derivatives and the composition thereof
This invention discloses method for inhibiting inflammation and reducing melanophilin expression with glycine derivatives and the composition thereof. The mentioned glycine derivatives can not only efficiently inhibit skin inflammation, but also can present significant melanophilin expression reduction.
10/23/14
20140314673
Treatment of cancer with dihydropyrazino-pyrazines
Provided herein are methods for treating or preventing head and neck squamous cell carcinoma characterized by deletion of chromosome 11q22 or loss of ataxia telangiectasia mutated expression, comprising administering an effective amount of a dihydropyrazino-pyrazine to a patient having head and neck squamous cell carcinoma characterized by deletion of chromosome 11q22 or loss of ataxia telangiectasia mutated expression.. .
10/23/14
20140311746
Use of chelants in formate-based solutions to dissolve residual filtercakes in subterranean wells
A wellbore fluid for dissolving a filtercake includes a chelating agent and an aqueous solution of carboxylate salt. The concentration of the chelating agent is up to 50 percent volume per volume (v/v) in the aqueous solution of carboxylate salt.
10/16/14
20140308674
Characterizing melanoma
The presently disclosed subject matter provides methods of characterizing a melanoma in a subject by measuring amounts of one or more rnas, mirnas, and/or polypeptides present in cancer-derived microvesicles isolated from a biological sample from the subject.. .
10/16/14
20140308316
Antigen presenting cancer vaccine with gamma interferon
The disclosure provides reagents, methods, and kits, for treating melanoma. The reagent encompasses interferon-gamma (ifn-gamma) responsive melanoma cells, where the cells are autophagic and non-apoptotic melanoma cells, and where the cells express mhc.
10/09/14
20140303212
Method for treating neurodegeneration using a p38mapk inhibitor
Ataxia-telangiectasia (a-t) is a progressive degenerative disorder that results in major neurological disability. In a-t patients, necropsy has revealed atrophy of all cerebellar cortical layers with extensive purkinje and granular cell loss.
10/09/14
20140302060
Gene signature for the prediction of nf-kappab activity
Methods for predicting nf-kappab (nf-kb) activity in a tumor, and more particularly to methods for predicting survival and therapeutic outcome, and selecting therapy in subjects with tumors, e.g., adenocarcinomas, e.g., lung adenocarcinomas and melanomas.. .
10/09/14
20140302006
Suppression of neuroendocrine diseases
The present invention relates to a method for suppressing neuroendocrine disease. The therapy employs use of a non-cytotoxic protease, which is targeted to a neuroendocrine tumour cell, preferably via a somatostatin or cortistatin receptor, a ghrh receptor, a ghrelin receptor, a bombesin receptor, a urotensin receptor a melanin-concentrating hormone receptor 1; a kiss-1 receptor or a prolactin-releasing peptide receptor.
10/09/14
20140301943
Induction of thyroid iodide-handling gene expression in human cancers
Dual suppression of the map kinase and pi3k/akt pathways showed synergistic or greatly enhanced anti-melanoma cell effects, compared to suppression of a single pathway, including the inhibition of cell proliferation, transformation and invasion, induction of g0/g1 cell cycle arrest and, importantly, cell apoptosis. Remarkably, suppression of either pathway induces the expression of thyroid iodide-handling genes and dual suppression of the two pathways synergistically and robustly induces expression of these genes, accompanied by uptake of radioiodine in the cells.
10/02/14
20140294920
Transdermal propranolol patch for treatment of malignant melanoma
A transdermal d propranolol or racemic propranolol patch for use as an adjunct to surgery in the treatment of malignant melanoma and/or tattoo related applications are herein disclosed.. .
09/25/14
20140288070
Compounds and methods for kinase modulation, and indications therefor
Compounds and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof are active on at least one raf protein kinase.
09/18/14
20140278701
Collaboration platform for digital media
A collaborative platform for the procurement and creation of digital media is disclosed. The platform includes methods and systems that provide a collaborative framework for collaborative digital media, connecting government/military, industry/freelancers and academia through a common, secure cloud service.
09/18/14
20140275084
Histone demethylase inhibitors
The present invention relates generally to compositions and methods for treating cancer and neoplastic diseases. Provided herein are substituted imidazole-pyridine derivative compounds and pharmaceutical compositions comprising said compounds.
09/18/14
20140274698
Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and insecticides
Or an agriculturally acceptable salt or ester thereof and (b) insecticides, including but not limited to, acephate, carbaryl, carbofuran, cartap, chlorpyrifos, cypermethrin, dimethoate, dinotefuran, etofenprox, fenitrothion, fipronil, imidacloprid, lambda-cyhalothrin, malathion, methamidophos, piperonyl butoxide, pymetrozine, spinetoram, spinosad, sulfoxaflor and triazophos. The compositions and methods provided herein control undesirable vegetation, e.g., in direct-seeded, water-seeded and transplanted rice, cereals, wheat, barley, oats, rye, sorghum, corn/maize, sugarcane, sunflower, oilseed rape, canola, sugar beet, soybean, cotton, pineapple, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, plantation crops, vegetables, industrial vegetation management (ivm) and rights-of-way (row)..
09/18/14
20140274697
Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and fungicides
The compositions and methods provided herein control undesirable vegetation, e.g., in direct-seeded, water-seeded and transplanted rice, cereals, wheat, barley, oats, rye, sorghum, corn/maize, sugarcane, sunflower, oilseed rape, canola, sugar beet, soybean, cotton, pineapple, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, plantation crops, vegetables, industrial vegetation management (ivm) and rights of way (row).. .
09/18/14
20140272986
Diagnostic test for predicting metastasis and recurrence in cutaneous melanoma
The invention as disclosed herein in encompasses a method for predicting the risk of metastasis of a primary cutaneous melanoma tumor, the method encompassing measuring the gene-expression levels of at least eight genes selected from a specific gene set in a sample taken from the primary cutaneous melanoma tumor; determining a gene-expression profile signature from the gene expression levels of the at least eight genes; comparing the gene-expression profile to the gene-expression profile of a predictive training set; and providing an indication as to whether the primary cutaneous melanoma tumor is a certain class of metastasis or treatment risk when the gene expression profile indicates that expression levels of at least eight genes are altered in a predictive manner as compared to the gene expression profile of the predictive training set.. .
09/18/14
20140271714
Induction of an immune response against dengue virus using the prime-boost approach
The invention relates to methods for the induction of an immune response to dengue virus. The method of inducing an immune response against dengue virus comprises administration of a non-replicating immunogen followed by a boost with a tetravalent live attenuated viral vaccine.
09/18/14
20140271546
Genes and gene signatures for diagnosis and treatment of melanoma
Panels of biomarkers, methods and systems are disclosed for determining gene expression, and diagnosing and treating melanoma.. .
09/18/14
20140271545
Methods for predicting risk of metastasis in cutaneous melanoma
The invention as disclosed herein in encompasses a method for predicting the risk of metastasis of a primary cutaneous melanoma tumor, the method encompassing measuring the gene-expression levels of at least eight genes selected from a specific gene set in a sample taken from the primary cutaneous melanoma tumor; determining a gene-expression profile signature from the gene expression levels of the at least eight genes; comparing the gene-expression profile to the gene-expression profile of a predictive training set; and providing an indication as to whether the primary cutaneous melanoma tumor is a certain class of metastasis or treatment risk when the gene expression profile indicates that expression levels of at least eight genes are altered in a predictive manner as compared to the gene expression profile of the predictive training set.. .
09/18/14
20140271509
Compositions for skin lightening and/or brightening
This disclosure describes compositions for skin lightening, brightening, whitening, reducing the appearance of age spot and/or improving the appearance of skin. The composition may include two or more tryosinase inhibiting compounds and one or more extracts from at least one plant species to inhibit alpha-melanoctye-stimulating hormone.
09/18/14
20140271506
Cosmetic compositions and methods for inhibiting melanin synthesis
A cosmetic composition suitable for topical application, for example, is provided. In some examples, the cosmetic composition may include undecylenoyl phenylalanine, hexyldecanol, and bisabolol.


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Elan topics: Folic Acid, Carbon Dioxide, Antibodies, Immune Response, High Energy, Inorganic Compounds, Electrolysis, Semiconductor Material, Semiconductor, Hydrogen Production From Water, Female Sexual Dysfunction, Dysfunction, Sexual Dysfunction, Mammography, Radiograph

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This listing is a sample listing of patent applications related to Elan for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Elan with additional patents listed. Browse our RSS directory or Search for other possible listings.
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