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Dysfunction

Dysfunction-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Engineered cardiac derived compositions and methods of use
The Johns Hopkins University
June 22, 2017 - N°20170173215

The present invention establishes a new standard for investigative studies of patient-specific, genetic cardiac diseases at a functional, tissue level by creating a novel platform for the study of cardiac related diseases, including cardiac conduction dysfunction, arrhythmias and depressed contractility for example. Provided herein are novel compositions of human engineered heart slices (ehs) formed from thin slices of decellularized cardiac ...
2-alkoxy-11-hydroxyaporphine derivatives and uses thereof
The Mclean Hospital Corporation
June 15, 2017 - N°20170166531

The invention features 2-alkoxy-11-hydroxyaporphine derivatives that selectively bind d2high receptors. The compounds are useful for imaging d2high receptors and for the treatment of diseases, such as parkinson's disease, sexual dysfunction, and depressive disorders.
Pharmaceutical composition comprising indole compound
Lg Life Sciences Ltd.
June 15, 2017 - N°20170165272

The present invention relates to a pharmaceutical composition comprising a compound of formula (1), (2) or (3) as defined in the specification for the prevention or treatment of diseases associated with oxidative stress, mitochondria dysfunction, hypoxic injury, necrosis and/or ischemic reperfusion injury, and a cosmetic composition comprising an indole compound having an antioxidant effect
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Dysfunction Patent Applications
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  • 289+ full patent PDF documents of Dysfunction-related inventions.
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Method of treating thermoregulatory dysfunction with paroxetine
Sebela International Limited
June 15, 2017 - N°20170165251

The present invention relates to a method for treating a patient suffering from a thermoregulatory dysfunction, especially hot flashes and flushes associated with hormonal changes due to naturally occurring menopause (whether male or female) or due to chemically or surgically induced menopause. The method is also applicable to treating the hot flashes, hot flushes, or night sweats associated with disease ...
Use of testosterone and a 5-ht1a agonist in the treatment of sexual dysfunction
Eb Ip Lybridos B.v.
June 08, 2017 - N°20170157142

The invention relates to the field of male and/or female sexual dysfunction. The invention specifically relates to the use of testosterone and a 5-ht1a agonist.
Method for treating erectile dysfunction
Eb Ip Lybridos B.v.
June 08, 2017 - N°20170157128

Erectile dysfunction in a male human patient is ameliorated by oral administration to the patient of prednisone followed by administration of sildenafil, preferably as sildenafil citrate.
Dysfunction Patent Pack
Download 289+ patent application PDFs
Dysfunction Patent Applications
Download 289+ Dysfunction-related PDFs
For professional research & prior art discovery
inventor
  • 289+ full patent PDF documents of Dysfunction-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Urinary prosthesis systems
Spinal Singularity, Inc.
June 08, 2017 - N°20170156838

The disclosure relates generally to an extended use systems and devices for management of bladder function for people with urinary dysfunction. The system includes a prosthesis which can include a retaining portion to prevent migration and a valve that can control fluid flow. The catheter can be placed inside the bladder using devices that facilitate insertion and extraction. The placement ...
Camptothecin conjugates of anti-cd22 antibodies for treatment of b cell diseases
Immunomedics, Inc.
June 01, 2017 - N°20170151356

Disclosed herein are compositions and methods of use comprising combinations of anti-cd22 antibodies with a therapeutic agent. The therapeutic agent may be attached to the anti-cd22 antibody or may be separately administered, either before, simultaneously with or after the anti-cd22 antibody. In preferred embodiments, the therapeutic agent is an antibody or fragment thereof that binds to an antigen different from ...
Compositions and methods for otologic prophylaxis and treatment
Otic Pharma Inc.
June 01, 2017 - N°20170151173

A prophylactic method for preventing otitis media or eustachian tube dysfunction, or reducing the severity of symptoms thereof, decreasing the risk of future otitis media, with or without ear infection, and associated effects including acute or permanent hearing loss, speech and balance problems, behavior problems and sleep problems caused by acute, intermittent episodic, recurrent or chronic otitis media, and the ...
Methods of identifying and monitoring mitochondrial dysfunction using monocyte screening
Otic Pharma Inc.
May 25, 2017 - N°20170146521

The present technology provides methods for detecting and diagnosing diseases and conditions characterized by mitochondrial dysfunction using monocytes as an indicator of the dysfunction.
Isoindoline compositions and methods for treating neurodegenerative disease
Otic Pharma Inc.
May 25, 2017 - N°20170144970

Isoindoline sigma-2 receptor antagonist compounds, pharmaceutical compositions comprising such compounds, and methods for inhibiting abeta-associated synapse loss or synaptic dysfunction in neuronal cells, modulating an abeta-associated membrane trafficking change in neuronal cells, and treating cognitive decline associated with abeta pathology are provided.
Mitochondrial-targeted antioxidants protect against mechanical ventilation-induced diaphragm dysfunction and skeletal muscle atrophy
Otic Pharma Inc.
May 25, 2017 - N°20170143784

The present disclosure provides methods and compositions for preventing or treating mv-induced or disuse-induced skeletal muscle infirmities in a mammalian subject. The methods further include administering to the subject an effective amount of an aromatic-cationic peptide.
Toxic rna inhibitors self-assembled in situ
Otic Pharma Inc.
May 25, 2017 - N°20170143703

Potent modulators of rna function can be assembled in cellulo by using the cell as a reaction vessel and a disease-causing rna as a catalyst. When designing small molecule effectors of function, a balance between permeability and potency must be struck. Low molecular weight compounds are more permeable while higher molecular weight compounds are more potent. The advantages of both ...
Dysfunction Patent Pack
Download 289+ patent application PDFs
Dysfunction Patent Applications
Download 289+ Dysfunction-related PDFs
For professional research & prior art discovery
inventor
  • 289+ full patent PDF documents of Dysfunction-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Gastric retentive pharmaceutical compositions for treatment and prevention of cns disorders
Otic Pharma Inc.
May 25, 2017 - N°20170143654

The present disclosure is directed to methods and compositions for ameliorating, preventing and treating central nervous system (cns) disorders. The invention aims to treat subjects suffering from, susceptible to, or diagnosed with cns disorders, and in particular, to treating patients suffering from those disorders which are associated with neurotransmitter system dysfunction.
Catheter deliverable foot implant and method of delivering the same
Otic Pharma Inc.
May 25, 2017 - N°20170143511

Methods and devices are disclosed for manipulating alignment of the foot to treat patients with flat feet, posterior tibial tendon dysfunction and metatarsophalangeal joint dysfunction. An inflatable implant is positioned in or about the sinus tarsi and/or first metatarsal-phalangeal joint of the foot. The implant is insertable by minimally invasive means and inflatable through a catheter or needle. Inflation ...
Stimulative electrotherapy using autonomic nervous system control
Otic Pharma Inc.
May 25, 2017 - N°20170143247

Methods for caring for a patient are disclosed. In some embodiments, the methods include measuring a first autonomic nervous system condition of the patient, calculating a first autonomic dysfunction based on the measured first autonomic nervous system condition, and calculating a first sympathovagal balance based on the first measured autonomic nervous system condition. The method also includes treating the patient, ...
Treatment of chronic kidney disease and other renal dysfunction using a gdf15 modulator
Aveo Pharmaceuticals, Inc.
May 18, 2017 - N°20170137506

The invention provides methods and compositions for treating a subject having a renal-related disorder, such as chronic kidney disease (ckd), end stage renal failure, diabetes, insulin resistance, kidney hypertrophy, kidney hypotrophy, polycystic kidney disease, proteinuria, hyperglycemia, hyperuricemia, gout, kidney stones, hypertension or hypertensive nephropathy, dyslipidemia, anemia and/or reduced erythropoietin production, iron deficiency or hyperfiltration. The methods and compositions use ...
Treatment of congestive heart failure and other cardiac dysfunction using a gdf15 modulator
Aveo Pharmaceuticals, Inc.
May 18, 2017 - N°20170137505

The invention provides methods and compositions of treating a subject having a cardiac-related disorder such as congestive or chronic heart failure (chf), cardiac hypertrophy, cardiac hypotrophy, and other cardiac myopathies/dystrophies. The methods comprise administering an effective amount of a composition that modulates, for example, reduces or inhibits, gdf 15 activity in the subject.
Topical nitric oxide systems and methods of use thereof
Transdermal Biotechnology, Inc.
May 18, 2017 - N°20170136059

The present invention generally relates to compositions and methods for transdermal drug delivery. The compositions can be used in a variety of applications, including treating erectile dysfunction or sexual dysfunction, treating wounds, or causing or promoting hair growth. For example, in one aspect, the present invention is generally directed to compositions for delivery of nitric oxide, transdermally and/or to ...
Di-isopropyl-phosphinoyl-alkanes as topical agents for the treatment of sensory discomfort
Transdermal Biotechnology, Inc.
May 18, 2017 - N°20170136045

The present discovery pertains generally to the field of therapeutic compounds. More specifically the present discovery pertains to certain di-isopropyl-phosphinoyl-alkanes as described herein, dipa-1-5, dipa-1-6, dipa-1-7, dipa-1-8, and dipa-1-9, collectively referred to herein as “dipa compounds”, that are useful, for example, in the treatment of disorders (e. G., diseases) including: sensory ...
Medical device for constricting venous outflow and for providing vibratory stimulus
Transdermal Biotechnology, Inc.
May 18, 2017 - N°20170135895

An apparatus for constricting blood flow and for providing vibratory stimulus to address erectile dysfunction. One implementation of the technology for enhancing erectile function, includes a single vibration unit or multiple vibration units. One implementation of the technology includes proximal and distal bands configured to annularly surround a penis close to the base of the penis and proximal to the ...
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