|| List of recent Domains-related patents
| Laglidadg homing endonuclease variants having mutations in two functional subdomains and use thereof|
A laglidadg homing endonuclease variant, having mutations in two separate subdomains, each binding a distinct part of a modified dna target half-site, said laglidadg homing endonuclease variant being able to cleave a chimeric dna target sequence comprising the nucleotides bound by each subdomain. Use of said herodimeric meganuclease and derived products for genetic engineering, genome therapy and antiviral therapy..
| Secure client-side communication between multiple domains|
Methods and systems for secure client-side communication between multiple domains is provided. Such methods and systems can provide for decreased communication latency particularly effective for dynamic multi-domain and/or multi-tenant environments while allowing for granular security or specific security of messages and operations with regard to users, user sessions, groups, organizations, permissions sets, applications, or any other logical delineation.
| Systems and methods for building a universal multimedia learner|
The present disclosure describes a method and system called “universal learner (ul),” which provides a unified framework to understand multimedia signals. The ul utilizes the loosely annotated multimedia data on the web, analyses it in various signal domains, such as text, image, audio and combinations thereof, and builds an association graph called the “multimedia brain,” which basically comprises visual signals, audio signals, text phrases and the like that capture a multitude of objects, experiences and their attributes and the links among them that capture similar intent or functional and contextual relationships..
| Providing recommendations using information determined for domains of interest|
Techniques are described for determining and using information related to domains of interest, such as by automatically analyzing documents and other information related to a domain in order to automatically determine relationships between particular terms within the domain. Such automatically determined information may then be used to assist users in obtaining information from the domain that is of interest (e.g., documents with contents that are relevant to user-specified terms and/or to other terms that are determined to be sufficiently related to the user-specified terms).
| Compositions and methods of treating disease with fgfr fusion proteins|
The invention provides fgfr fusion proteins, methods of making them, and methods of using them to treat proliferative disorders, including cancers and disorders of angiogenesis. The fgfr fusion molecules can be made in cho cells and may comprise deletion mutations in the extracellular domains of the fgfrs which improve their stability.
| Process for fabricating a transistor comprising nanoscale semiconductor features using block copolymers|
A process for fabricating one transistor, comprising a semiconductor region, comprising a source region, a drain region, and a channel region covered with a gate, comprises: production of an primary etching mask on the surface of the semiconductor region, said mask containing at least one primary aperture; depositing in said primary aperture a block copolymer containing, in alternation, at least first polymer domains and second polymer domains; removing either a series of first polymer domains or a series of second polymer domains in order to create a secondary mask containing secondary apertures; etching said active region through said secondary apertures in order to define nanoscale self-aligned semiconductor features; producing said gate on the surface of said self-aligned semiconductor features.. .
| Soluble heavy-chain only antibodies|
The present invention provides a high affinity, antigen-specific, soluble heavy chain-only antibody which: lacks hallmark camelid-related amino acid substitutions and has fr2 substitutions which are not found in antibodies which comprise heavy and light chain; shows increased net hydrophobicity within cdr1 and an increased number of charged amino acids present in cdr3; and comprises one or more amino acid substitutions within the framework β-pleated sheet leading to increased net hydrophobicity within fr1 and increased number of charged amino acids present in fr3. Also provided are vh domains having the same properties, gene segments for their production, methods for their production, transgenic animals and uses of the antibody of the vh domains in therapy..
| Scaling up/out the number of broadcast domains in network virtualization environments|
A method for handling multicast traffic is presented. A method of handling multicast traffic according to some embodiments of the present invention includes forming ip multicast (ipmc) groups of hypervisors based on broadcast domains; and directing multicast traffic from a broadcast domain on a source hypervisor to hypervisors that are members of the ipmc group..
| Esd protection device for circuits with multiple power domains|
A esd protection scheme is disclosed for circuits with multiple power domains. Embodiments include: coupling a first power clamp to a first power rail and a first ground rail of a first domain; coupling a second power clamp to a second power rail and a second ground rail of a second domain; providing a blocking circuit for blocking current from an esd event; providing an i/o interface connection in the first domain for transmitting signals from the first domain to the blocking circuit; providing a core interface connection in the second domain for transmitting signals from the blocking circuit to the second domain; coupling an input connection of the blocking circuit to the i/o interface connection; and coupling an output connection of the blocking circuit to a core interface connection..
| Liquid crystal display device|
A liquid crystal display device includes a liquid crystal layer extending in a display region; and a tft substrate and a counter substrate affixed to each other so as to sandwich the liquid crystal layer therebetween. The tft substrate is provided with a pixel electrode corresponding to each of a plurality of pixels.
| Polymer/liquid crystal composite and liquid crystal display device including the same|
The occurrence of a defective orientation of a polymer/liquid crystal composite is suppressed. In addition, the occurrence of defective display of a liquid crystal display device including the polymer/liquid crystal composite is suppressed.
|Method and apparatus for quantifying threat situations to recognize network threat in advance|
An apparatus for quantifying network threat situations includes a traffic analyzing unit to analyze packet patterns of traffics occurring on a target network being monitored to extract one or more suspicious domains. An ip monitoring unit gives security levels among a plurality of security levels to the suspicious domains according to the number of access ips accessing the suspicious domains.
|Security threat detection based on indications in big data of access to newly registered domains|
Domain names are determined for each computational event in a set, each event detailing requests or posts of webpages. A number of events or accesses associated with each domain name within a time period is determined.
|Systems and methods for portfolio monitoring|
Systems and methods for determining portfolio monitoring are provided. More specifically, various embodiments of the present invention relate to systems and methods for monitoring a portfolio of domain names for expiration, availability, and collection of redirection analytics.
|System for detecting the presence of rogue domain name service providers through passive monitoring|
A method, system, and computer program product embodied in a computer readable storage medium are disclosed for identifying a rogue domain name service (dns) server. Embodiments include passively monitoring traffic on a target network; and identifying a dns resolution response in the traffic on the network.
|Non-natural consensus albumin binding domains|
Non-natural albumin binding domains, polynucleotides encoding thereof and methods of making and using these domains and polynucleotides are useful in controlling the half-life of therapeutic molecules for patients.. .
|Interface for communication between voltage domains|
In one or more embodiments, circuitry is provided for isolation and communication of signals between circuits operating in different voltage domains using capacitive coupling. The capacitive coupling is provided by one or more capacitive structures having a breakdown voltage that is defined by way of the various components and their spacing.
|Peptides and related molecules that modulate nerve growth factor activity|
The present invention relates to certain biologically active peptides and polypeptides which can be used as therapeutics or prophylactics against diseases or disorders linked to ngf as the causative agent. In one aspect of the present invention, pharmacologically active polypeptides comprising peptides linked to one or more fc domains are provided..
|Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics|
This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against kiaa0746, cd20 or cd55 antigens, which are differentially expressed in cancer and in specific blood cells, and diagnostic and therapeutic usages.
|System and method for applying an extended multipoint protocol to wireless access systems|
A system and method for applying an extended multipoint control protocols to wireless access systems. A medium-to-medium adaptor can be provided in an adaptor node that can interface with an upstream optical line terminal in a pon domain and a downstream device in a non-pon wireless domain.
|Method and apparatus for extending multipoint control protocols to mixed media access systems|
A method and apparatus for extending multipoint control protocols to mixed media access systems. A medium-to-medium adaptor can be provided in an adaptor node that can interface with an upstream optical line terminal in a pon domain and a downstream device in a non-pon domain.
|Transmission device, reception device, transmission method, and reception method|
A transmission device capable of flexibly setting the transmission mode, even in cases when the candidates for the resource domain to be used to transmit a control signal to a terminal include both a first downlink resource domain that can be used as either a control channel or a data channel and a second downlink resource domain that can be used as a control channel, wherein a transmission mode setting unit (101) sets one transmission mode for each of the first and second downlink resource domains, said transmission mode being selected from among a plurality of transmission modes in which a plurality of control signal formats and the transmission methods that correspond to the control signal formats and are used to transmit data to a terminal (200) have been associated.. .
|Intermediate network in a ring topology, and method for setting up a network connection between two network domains|
The invention relates to an intermediate network (1) in a ring topology for setting up a connection between two network domains (2a, 2b), having a first marginal node (6a) and a second marginal node (7a), which are marginal nodes in a first network domain (2a) and which are connected to one another by means of a first network connection (9a) within the first network domain (2a), a third marginal node (6b) and a fourth marginal node (7b), which are marginal nodes in a second network domain (2b) and which are connected to one another by means of a second network connection (9b) within the second network domain (2b), a first virtual network connection (4a), which connects the first (6a) and the third (6b) marginal nodes via an intermediate network (3), and a second virtual network connection (4b), which connects the second (7a) and the fourth (7b) marginal nodes via the intermediate network (3). The first network connection (9a), the second network connection (9b), the first virtual network connection (4a) and the second virtual network connection (4b) have a ring topology on which a connection redundancy protocol is implemented..
|Coding and multiplexing of control information in a wireless communication system|
Techniques for sending control information in a wireless communication system are described. In an aspect, a ue spreads control information across frequency with a dft and across time with an orthogonal sequence to obtain output data for the control information.
|Magnetic shift register memory device|
In one embodiment, the invention is a magnetic shift register memory device. One embodiment of a memory cell includes a magnetic column including a plurality of magnetic domains, a reader coupled to the magnetic column, for reading data from the magnetic domains, a temporary memory for storing data read from the magnetic domains, and a writer coupled to the magnetic column, for writing data in the temporary memory to the magnetic domains..
|Preventing electrostatic discharge (esd) failures across voltage domains|
An electrostatic discharge (esd) device implemented within a power domain to mitigate esd events imparted from another power domain for reducing integrated circuit (ic) failures. A first power domain includes an interface where esd events are received and an output that can impart esd event voltages on other components.
|Intelligent power controller|
A method, apparatus, and system in which an interconnect for an integrated circuit communicates transactions between one or more initiator intellectual property (ip) cores and one or more target ip cores coupled to the interconnect, including a power manager having a hierarchy of two or more layers including a hardware logic portion to control a power consumption of two or more domains in the integrated circuit, where each layer of the power manager performs its own function; wherein the power manager has its own dedicated cpu or dedicated state machine to execute power management instructions; and wherein the power manager controls the power consumption of two or more domains without using a cpu ip core utilized by other ip cores on the integrated circuit to execute power management instructions.. .
|Method and system for monitoring and redirecting http requests away from unintended web sites|
Embodiments are described for a system and method for redirecting internet traffic away from illegitimate web sites. A redirect process includes a typo identifier engine and a direct navigation engine.
|Method for managing network system|
Interdomain federation, for example, generation or management of a virtual network (slice) that extends among domains can be performed without changing a function of a server or a node of a network domain without a function to manage the other domain. A pseudo node receiving a management message with the same protocol as a general node is added, in interdomain management information from an own domain, the other domain part in management information is received as the management information by the pseudo node (the other domain part is concealed) and when interdomain management information is transmitted to the other domain through the pseudo node by a federation protocol and the pseudo node and the interdomain management information is received from the other domain, the other domain part in the management information is bound as the management information of the pseudo node (the other domain part is concealed) and transmitted to a management server of an own domain..
|Online advertising valuation apparatus and method|
A method comprising for determining the value provided to an advertiser through the advertiser's online advertisements. The method may begin with providing an online advertisement linked to content.
|Polycarbonate copolymers via controlled radical polymerization|
In one aspect, the invention relates to relates to copolymer compositions comprising domains of polycarbonate and polyacrylate, and to methods of preparing the copolymers, wherein the method comprises reacting a polycarbonate macroinitator with a vinyl monomer by atom transfer radical polymerization. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention..
|Novel antigen binding proteins|
The present invention provides novel antigen-binding proteins derived from human germline vh domains, having improved expression and improved biophysical characteristics.. .
|Engineered amine dehydrogenases and methods of use thereof|
Non-naturally occurring amine dehydrogenases (amdh) and methods of use thereof the produce chiral amines are disclosed. The amdh are variants of amino acid dehydrogenases.
|Recombinant t cell ligands and antibodies that bind b cells for the treatment of autoimmune diseases|
Methods are disclosed for treating or inhibiting an autoimmune disease in a subject. In some embodiments, the disclosed methods include administering to the subject a therapeutically effective amount of one or more major histocompatibility complex (mhc) molecules including covalently linked first, second and third domains; wherein the first domain is an mhc class ii β1 domain and the second domain is an mhc class ii α1 domain, wherein the amino terminus of the α1 domain is covalently linked to the carboxy terminus of the β1 domain; or wherein the first domain is an mhc class i α1 domain and the second domain is an mhc class i α2 domain, wherein the amino terminus of the α2 domain is covalently linked to the carboxy terminus of the α1 domain; and wherein the third domain is covalently linked to the first domain and comprises an antigen associated with the autoimmune disorder.
|Aflaxtoxin resistant poultry|
The present disclosure includes methods of improving the quality of poultry and the efficiency of its production. Specifically, single nucleotide polymorphisms (snps) have been identified in signature domains and conserved residues found in α-class turkey glutathione s-transferase (gsta) genes.
|Computerized system and method for handling network traffic|
Methods and systems for processing network content associated with multiple virtual domains are provided. According to one embodiment, a service daemon process is instantiated within a firewall to handle content processing of network traffic of virtual domains by aggregating communication channels associated with the virtual domains and by applying an appropriate content processing policy for the corresponding virtual domain.
|Method of loading data into a portable secure token|
The invention is a method for loading data into a portable secure token comprising a plurality of security domains. A first security domain comprises a first administration agent and a second security domain comprises a second administration agent.
|Creating federated associate identifiers to positively identify associates interfacing across multiple business applications|
Methods, apparatus, systems and computer program products are described and claimed that provide for automatically and positively determining that an associate accessing a business domain/application using an application-specific associate identifier is the same associate that is accessing another business domain/application using another application-specific associate identifier. Once the positive determination of same associate is made, a federated identifier key is generated and applied to all of the platforms in which the associate can be positively identified, so as to globally identify the associates across multiple enterprise-wide domains/applications.
|Computing system with domain independence orientation mechanism and method of operation thereof|
A computing system includes: a gather module configured to gather a distribution of a class bias score for a feature and across multiple domains; a transformation module, coupled to the gather module, configured to generate a transformation for a characteristic of a domain independence based on the class bias score; and a consolidation module, coupled to the transformation module, configured to compute a domain-independent class-bias score based on the transformation.. .
|Managing secure sharing of private medication information across security domains|
Authorization for access is requested and granted for the user to access one or more of the caseloads.. .
|Multispecific antibody targeting and multivalency through modular recognition domains|
Antibodies containing one or more modular recognition domains (mrds) that can be used to target the antibodies to specific sites are described. The use of antibodies containing one or more modular recognition domains to treat disease, and methods of making antibodies containing one or more modular recognition domains are also described..
|Engineering of immunoglobulin domains|
The present invention provides a single domain antibody (sdab) scaffold comprising one or more than one non-canonical disulfide bond in the framework region (fr). The one or more than one non-canonical disulfide bond may be formed between cysteines introduced by mutations in fr2 and fr3.
|Multiple domain smartphone|
A smartphone is adapted, through software modifications, to provide multiple operating domains or domains that provide differing levels of security and reliability. Each operating domain is isolated from the others.