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Dna Sequence

Dna Sequence-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Methods for variant detection
Integrated Dna Technologies, Inc.
September 14, 2017 - N°20170260583

The invention can be used to provide a more efficient and less error-prone method of detecting variants in dna, such as snps and indels. The invention also provides a method for performing inexpensive multiplex assays. The invention also provides methods for detection of dna sequences altered after cleavage by a targetable endonuclease, such as the crispr cas9 protein from the ...
Dividing of reporter proteins by dna sequences and its application in site specific recombination
Integrated Dna Technologies, Inc.
September 07, 2017 - N°20170253938

Methods and constructs for inserting an intron into a reporter protein coding sequence in a eukaryotic cell and their application of monitoring and reporting genomic modifications are provided. Various related compositions, cells and kits are also provided.
Methods for variant detection
Integrated Dna Technologies
September 07, 2017 - N°20170253925

The invention can be used to provide a more efficient and less error-prone method of detecting variants in dna, such as snps and indels. The invention also provides a method for performing inexpensive multiplex assays. The invention also provides methods for detection of dna sequences altered after cleavage by a targetable endonuclease, such as the crispr cas9 protein from the ...
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Dna sequence, and recombinant preparation of group 4 major allergens from cereals
Merck Patent Gmbh
August 31, 2017 - N°20170246317

The present invention relates to the provision of dna sequences of group 4 mayor allergens from cereals. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant dna molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilised for the therapy of pollen-allergic diseases. The proteins ...
Genetically stable recombinant modified vaccinia ankara (rmva) vaccines and methods of preparation thereof
City Of Hope
August 31, 2017 - N°20170246292

A vaccine comprising an immunologically effective amount of recombinant modified vaccinia ankara (rmva) virus which is genetically stable after serial passage and produced by a) constructing a transfer plasmid vector comprising a modified h5 (mh5) promoter operably linked to a dna sequence encoding a heterologous foreign protein antigen, wherein the expression of said dna sequence is under the control of ...
Sidt1 gene controlling determinate growth habit in sesame and snp molecular marker thereof
Henan Sesame Research Center, Henan Academy Of Agricultural Sciences
August 17, 2017 - N°20170233831

A sidt1 gene controlling a determinate growth habit of sesame, the gene having a length of 1809 bp and including four exons and three introns. The sidt1 gene is located on the fourth chromosome of sesame and in an 18. 0-19. 2 cm interval of the eighth linkage group on an snp genetic map of sesame. The dna sequence of the sidt1 gene ...
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Compositions and methods for transcription-based crispr-cas dna editing
The Rockefeller University
August 17, 2017 - N°20170233729

Provided are compositions and methods for cleaving a dna sequence in a cell. The methods involve comprising introducing into a cell a recombinant vector containing a clustered regularly interspaced short palindromic repeats (crispr) system. The system includes a crispr rna (crrna) targeted to a dna sequence in the cell that is operatively linked to a promoter; and crispr-associated enzymes (cas) 10, ...
Finding relatives in a database
23andme, Inc.
August 10, 2017 - N°20170228498

Determining relative relationships of people who share a common ancestor within at least a threshold number of generations includes: receiving recombinable deoxyribonucleic acid (dna) sequence information of a first user and recombinable dna sequence information of a plurality of users; processing, using one or more computer processors, the recombinable dna sequence information of the plurality of users in parallel; determining, ...
Biomarkers for rheumatoid arthritis and usage thereof
Bgi Shenzhen
August 10, 2017 - N°20170226565

Biomarkers and methods for predicting risk of a disease in particular ra are provided. Sequences of dna are obtained. The dna may be extracted from a sample that is collected from a subject. A relative abundance of a biomarker is then calculated based on the sequences of the dna. The biomarker comprises a dna sequence in a genome of lactobacillus ...
Solubility and affinity tag for recombinant protein expression and purification
Bgi Shenzhen
August 10, 2017 - N°20170226489

Systems and methods of coding for and isolating a fusion protein are provided. The fusion protein may be expressed by a dna sequence and comprise an adenylate kinase linked by its carboxy-terminus to a biologically active polypeptide or protein. Later processing steps include isolating the biologically active polypeptide or protein via affinity elution of the fusion proteins with substrate analog ...
Cd7 nanobodies, encoding sequence and use thereof
Persongen Biomedicine (suzhou) Co., Ltd.
August 10, 2017 - N°20170226204

Provided is a nanometer antibody for human cd7 molecule and an encoding dna sequence thereof. The nanometer antibody can be efficiently expressed in escherichia coli, and can be used for preparing an agent for the detection of cd7 molecule and targeted therapy.
Methods and products for expressing proteins in cells
Factor Bioscience Inc.
August 03, 2017 - N°20170218400

The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the dna sequence of a ...
Nucleotide sequence exclusion enrichment by droplet sorting (needls)
Samplix S.a.r.l.
July 27, 2017 - N°20170211127

The present invention pertains to an in vitro method in which a targeted dna molecule containing a dna sequence of interest is enriched by a) general amplification of dna molecules in a multiple of droplets each containing less than 0. 5 target dna molecule on average (404), b) specific detection of the target dna molecule in each of the droplets (405), and c) physically ...
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Functionalized dna dendrimers for gene delivery to cells
Lankenau Institute Of Medical Research
July 27, 2017 - N°20170209599

Compositions are disclosed which comprise a dna dendrimer having one or more dna sequences linked thereto, the dna sequences comprising dna sequences encoding a polypeptide or regulatory rna linked to dna sequences that regulate expression of the dna sequences encoding a polypeptide or regulatory rna to produce an rna coding for the polypeptide or to produce the regulatory rna. Also ...
Maize event dp-032218-9 and methods for detection thereof
E. I. Du Pont De Nemours And Company
July 20, 2017 - N°20170204473

The disclosure provides dna compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize dp-032218-9 event based on the dna sequence of the recombinant construct inserted into the maize genome and the dna sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
Method and systems for processing polymeric sequence data and related information
Annai Systems Inc.
July 13, 2017 - N°20170199962

Methods and systems for organizing, representing and processing polymeric sequence information, including biopolymeric sequence information such as dna sequence information and related information are disclosed herein. Polymeric sequence and associated information may be represented using a plurality of data units, each of which includes one or more headers and a payload containing a representation of a segment of the polymeric ...
Ungulates with genetically modified immune systems
Revivicor, Inc.
June 29, 2017 - N°20170183685

The present invention provides ungulate animals, tissue and organs as well as cells and cell lines derived from such animals, tissue and organs, which lack expression of functional endogenous immunoglobulin loci. The present invention also provides ungulate animals, tissue and organs as well as cells and cell lines derived from such animals, tissue and organs, which express xenogenous, such as ...
Methods for detecting target dna sequences
Vetgenomics, S.l.
June 22, 2017 - N°20170175208

The invention relates to methods for detecting target dna sequences, particularly for detecting leishmania infection, comprising a recombinase-polymerase isothermal amplification and detection by electrochemistry. The invention also relates to kits and oligonucleotides for performing said methods.
Dna probe sequence for genetic sex identification of litopenaeus vannamei and acquisition method
Institute Of Oceanology, Chinese Academy Of Sciences
June 22, 2017 - N°20170175188

The present invention relates to a dna sequence showing difference between the female and male individuals of litopenaeus vannamei and its corresponding acquired method. The method comprises: respectively conducting high-through put sequencing on the mixing pools of female individuals and male individuals in by high-through put sequencing platform; conducting bioinformatic analysis on the sequencing results to screen out sequences showing ...
Corn plant mon88017 and compositions and methods for detection thereof
Monsanto Technology Llc
June 15, 2017 - N°20170166984

The present invention provides a corn plant designated mon88017 and dna compositions contained therein. Also provided are assays for detecting the presence of the corn plant mon88017 based on a dna sequence and the use of this dna sequence as a molecular marker in a dna detection method.
Methods for dna preparation for multiplex high throughput targeted sequencing
Shoreline Biome, Llc
June 15, 2017 - N°20170166956

Disclosed are methods for parallel single-step dna purification starting with multiple crude biological samples for subsequent parallel pcr amplification of target dna that attaches a unique dna sequence tag (barcode) allowing all parallel processed samples to be combined into a single high-throughput sequencing run. The methods disclosed herein can be used to prepare and sequence dozens or hundreds of targeted ...
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