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Diseases patents



      
           
This page is updated frequently with new Diseases-related patent applications. Subscribe to the Diseases RSS feed to automatically get the update: related Diseases RSS feeds. RSS updates for this page: Diseases RSS RSS


Date/App# patent app List of recent Diseases-related patents
08/28/14
20140244283
 Pathology, radiology and other medical or surgical specialties quality assurance patent thumbnailnew patent Pathology, radiology and other medical or surgical specialties quality assurance
Current electronic health systems and government sponsored international classification of diseases (idc-10) do not have the flexibility to describe diagnoses that are not clearly benign or cancerous and cannot relay recommendations from pathologist, radiologist, or other specialist. Software codes enable any specialty to efficiently communicate additional recommendations with time metrics to their referring sources.
08/28/14
20140244183
 Molecular profiling of tumors patent thumbnailnew patent Molecular profiling of tumors
Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to identify treatments for a disease, such as treatments that were not initially identified as a treatment for the disease or not expected to be a treatment for a particular disease..
08/28/14
20140244182
 Molecular profiling of tumors patent thumbnailnew patent Molecular profiling of tumors
Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to identify treatments for a disease, such as treatments that were not initially identified as a treatment for the disease or not expected to be a treatment for a particular disease..
08/28/14
20140243651
 Health diagnosis system using image information patent thumbnailnew patent Health diagnosis system using image information
A health diagnosis system comprises information input unit for receiving basic information and image information for user's body part; recognition unit for recognizing the body part as object by auto search based on image information received by input unit; analysis unit drawing diagnosis results by analyzing image information recognized by the said recognition unit according to checkup elements for each body part, comparing and analyzing the analyzed information and standard information recorded in pathological information database unit; pathological information database unit for storing standard information which can diagnose names and severities of diseases by checkup elements for each body part for the analysis unit to draw the diagnosis results by comparing and analyzing the analyzed information and the standard information; and diagnosis results database unit for recording the image information received by the information input unit for user's body parts and diagnosis results drawn by the said analysis unit.. .
08/28/14
20140243532
 Novel precursors of glutamate derivatives patent thumbnailnew patent Novel precursors of glutamate derivatives
This invention relates to novel precursors suitable for 18f radiolabeling of glutamate derivatives, methods for preparing such compounds and its intermediates, compositions comprising such compounds, kits comprising such compounds or compositions and methods for 18f radiolabeling of glutamate derivatives wherein the obtained 18f radiolabeled glutamate derivatives are suitable for diagnostic imaging by positron emission tomography (pet) of proliferative diseases e.g. Tumor in mammals..
08/28/14
20140243528
 Rosuvastatin enantiomer compounds patent thumbnailnew patent Rosuvastatin enantiomer compounds
The invention discloses a method for the treatment of diseases, particularly those diseases characterized by diminished or aberrant cellular function, including aids, cancer, and alzheimer's disease. The method comprises administering a therapeutically effective amount of rosuvastatin enantiomer compounds in their (3r, 5r), (3s, 5r), or (3s, 5s) configurations, or pharmaceutically acceptable salts thereof biologically-active rosuvastatin enantiomer compounds with (3r, 5r), (3s, 5r), and (3s, 5s) stereochemistry are also disclosed..
08/28/14
20140243517
 Methods of producing c-aryl glucoside sglt2 inhibitors patent thumbnailnew patent Methods of producing c-aryl glucoside sglt2 inhibitors
Method for the production of c-aryl glucoside sglt2 inhibitors useful for the treatment of diabetes and related diseases. And intermediates thereof.
08/28/14
20140243501
 Histone deacetylase inhibitors and synthetic method thereof and use thereof in manufacture of medicaments patent thumbnailnew patent Histone deacetylase inhibitors and synthetic method thereof and use thereof in manufacture of medicaments
The invention provides histone deacetylase (hdac) inhibitors shown as formula i, where r1 to r8 are as defined in the specification. The invention also provides methods for synthesis of these compounds and applications of these compounds in preparing pharmaceuticals for preventing or treating mammal diseases related to the dysregulation of hdac..
08/28/14
20140243425
 Controlled release compositions for modulating free-radical induced damage and methods of use thereof patent thumbnailnew patent Controlled release compositions for modulating free-radical induced damage and methods of use thereof
Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with free-radical modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).. .
08/28/14
20140243424
 Catechol derivatives for treatment of oxidative stress diseases patent thumbnailnew patent Catechol derivatives for treatment of oxidative stress diseases
Methods of treating or suppressing oxidative stress disorders affecting normal electron flow in the cells, including mitochondrial diseases, impaired energy processing disorders, neurodegenerative diseases, diseases of aging and diseases caused by reactive oxygen species are disclosed, as well as compounds useful in the methods of the invention, such as such as catechol or ortho-quinone derivatives of formula (i).. .
08/28/14
20140243420
new patent Anticonvulsant activity of turmeric oil and bisabolene sesquiterpenoids
The present invention relates to the anti-convulsant activity of turmeric oil and its volatile bisabolene sesquiterpenoids ar-turmerone, α-turmerone, β-turmerone (curlone) and α-atlantone, as an anticonvulsant agent for the treatment of epilepsy and/or as therapeutic agents for the treatment of disorders of the central nervous system, including tremor, pain, mood disorders (including depression, bipolar disorder, attention deficit-hyperactivity disorder, and schizophrenia), and neurodegenerative diseases.. .
08/28/14
20140243419
new patent Mucosally-applied agent for prevention, amelioration or treatment of retinal disease
Application of a pharmaceutical preparation comprising geranylgeranylacetone to the mucosa of, for example, the eye, nose, oral cavity or pharynx can efficiently prevent, ameliorate or treat retinal diseases such as glaucoma, retinitis pigmentosa, age-related macular degeneration, and diabetic retinopathy.. .
08/28/14
20140243406
new patent Methods for treating or preventing fatigue
The present invention relates to the use of compounds of the invention for treatment and/or prevention of fatigue, including fatigue associated with diseases or treatments.. .
08/28/14
20140243399
new patent Engineered nucleic acids and methods of use thereof
Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger rnas, and are useful to treat or prevent diseases, disorders or conditions, or to improve a subject's heath or wellbeing..
08/28/14
20140243398
new patent Irs modulators
This invention is directed to a general method for the chronic treatment, potential cure, or prevention of various metabolic and related diseases in people, including diabetes, by modulating irs2 activity in cells and tissues in the body. Irs1 and irs2 are part of the insulin or insulin-like growth factor signaling pathway.
08/28/14
20140243393
new patent Methods of diagnosing and treating motor neuron diseases
Use of an agent which upregulates an activity or amount of mirna-9 or mirna-9* is disclosed for the preparation of a medicament for the treatment of a motor neuron disease (mnd).. .
08/28/14
20140243389
new patent Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.. .
08/28/14
20140243382
new patent Inhibitors of c-fms kinase
Wherein z, x, j, r2 and w are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase. Methods of treating autoimmune diseases; and diseases with an inflammatory component; treating metastasis from ovarian cancer, uterine cancer, breast cancer, prostate cancer, lung cancer, colon cancer, stomach cancer, hairy cell leukemia; and treating pain, including skeletal pain caused by tumor metastasis or osteoarthritis, or visceral, inflammatory, and neurogenic pain; as well as osteoporosis, paget's disease, and other diseases in which bone resorption mediates morbidity including rheumatoid arthritis, and other forms of inflammatory arthritis, osteoarthritis, prosthesis failure, osteolytic sarcoma, myeloma, and tumor metastasis to bone with the compounds of formula i, are also provided..
08/28/14
20140243373
new patent Cyclic amine derivatives as ep4 receptor agonists
The present invention therefore relates to novel cyclic amine derivative compounds, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments, inter alia for the treatment or alleviation of prostaglandin e mediated diseases such as pain, glaucoma, ulcerative colitis and osteoporosis.. .
08/28/14
20140243368
new patent Piperidinyl alkyne orexin receptor antagonists
The present invention is directed to piperidinyl alkyne compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the piperidinyl alkyne compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved.
08/28/14
20140243366
new patent Compounds that modulate intracellular calcium
Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (soc) channels. Also described herein are methods of using such soc channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of soc channel activity..
08/28/14
20140243365
new patent Compounds modulating c-fms and/or c-kit activity and uses therefor
Compounds active on the receptor protein tyrosine kinases c-kit and/or c-fms are provided herewith. Also provided herewith are compositions useful for treatment of c-kit mediated diseases or conditions and/or c-fms-mediated diseases or conditions, and methods for the use thereof..
08/28/14
20140243360
new patent Heteroaryl substituted pyrrolo[2,3-b] pyridines and pyrrolo[2,3-b] pyrimidines as janus kinase inhibitors
The present invention provides heteroaryl substituted pyrrolo[2,3-b]pyridines and heteroaryl substituted pyrrolo[2,3-b]pyrimidines that modulate the activity of janus kinases and are useful in the treatment of diseases related to activity of janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.. .
08/28/14
20140243358
new patent Method of preventing and treating hepatic disease using a2b adenosine receptor antagonists
The invention is related to methods of preventing and treating hepatic fibrosis using a2b adenosine receptor antagonists and utility in the treatment and prevention of liver damage caused by alcohol abuse, surgical intervention, viral hepatitis, the ingestion of hepatotoxic drugs, or other hepatic diseases. The invention also relates to pharmaceutical compositions for use in the method..
08/28/14
20140243355
new patent Inhibitors of bruton's tyrosine kinase
Disclosed herein are compounds that form covalent bonds with bruton's tyrosine kinase (btk). Also described are irreversible inhibitors of btk.
08/28/14
20140243353
new patent 5- or 6-substituted 3-hydroxy-2(1h)-pyridinones as d-amino acid oxidase (daao) inhibitors in therapy of diseases such as schizophrenia, cognitive disorder and paid
The present invention provides compounds of formula (i) and pharmaceutically acceptable salts thereof, wherein r1 is hydrogen or fluorine, one of a and b is r2, the other is a group —x—y—r3. R3 represents a carbocyclic or heterocyclic ring.
08/28/14
20140243349
new patent Gamma-diketones as wnt/beta -catenin signaling pathway activators
The present disclosure provides γ-diketones or analogs thereof, that activate wnt/β-catenin signaling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries or spine injuries, brain atrophy/neurological disorders related to the differentiation and development of the central nervous system, including parkinson's disease, strokes, ischemic cerebral disease, epilepsy, alzheimer's disease, depression, bipolar disorder, schizophrenia; otic disorders like cochlear hair cell loss; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, such as hair loss, hematopoiesis related diseases and tissue regeneration related diseases.. .
08/28/14
20140243347
new patent Substituted 3,4-dihydropyrrolo[1,2-a]pyrazin-1(2h)-one derivatives as kinases inhibitors
The present invention relates to substituted 3,4-dihydropyrrolo[1,2-a]pyrazin-1(2h)-one derivatives which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them..
08/28/14
20140243337
new patent Phenyl carboxamide-containing spleen tyrosine kinase (syk) inhibitors
The invention provides certain phenyl carboxamide-containing compounds of the formula (i); or pharmaceutically acceptable salts thereof, wherein a and b are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by spleen tyrosine kinase (syk) kinase..
08/28/14
20140243336
new patent 2-pyridyl carboxamide-containing spleen tyrosine kinase (syk) inhibitors
The invention provides certain 2-pyridyl carboxamide-containing compounds of the formula (i) or pharmaceutically acceptable salts thereof, wherein a and b are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by spleen tyrosine kinase (syk) kinase..
08/28/14
20140243335
new patent Substituted hydoxamic acids and uses thereof
Wherein r1, r1b, r2a, r2b, r2c, and r2d have values as described in the specification, useful as inhibitors of hdac6. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of proliferative, inflammatory, infectious, neurological or cardiovascular diseases or disorders..
08/28/14
20140243334
new patent Substituted hydoxamic acids and uses thereof
Wherein r1a, r1b, r1c, r2a, r2b, r2c, and r2d have values as described in the specification, useful as inhibitors of hdac6. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of proliferative, inflammatory, infectious, neurological or cardiovascular diseases or disorders..
08/28/14
20140243330
new patent Phosphoinositide 3-kinase inhibitor with a zinc binding moiety
Pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase..
08/28/14
20140243313
new patent Tricyclic compounds useful as neurogenic and neuroprotective agents
The invention disclosed herein is direct to compounds of formula i and pharmaceutically acceptable salts thereof, which are useful in treating neurodegenerative diseases and promoting the generation or survival of neurons in the mammalian brain. The invention also comprises pharmaceutical compositions comprising a therapeutically effective amount of compound of formula i or a pharmaceutically acceptable salt thereof.
08/28/14
20140243309
new patent Cycloalkylnitrile pyrazole carboxamides as janus kinase inhibitors
The instant invention provides compounds of formula i which are jak inhibitors, and as such are useful for the treatment of jak-mediated diseases such as rheumatoid arthritis, asthma, copd and cancer.. .
08/28/14
20140243308
new patent Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
The present invention relates to substituted imidazopyridazines and substituted benzimidazoles, as well as pharmaceutical compositions comprising the same, which are fgfr3 inhibitors useful in the treatment of cancer and other diseases.. .
08/28/14
20140243306
new patent Novel pyrrolo pyrimidine derivatives
The present invention describes new pyrrolo pyrimidine derivatives and pharmaceutically acceptable salts thereof which appear to interact with bruton's tyrosine kinase (btk). Accordingly, the novel pyrrolo pyrimidines may be effective in the treatment of autoimmune disorders, inflammatory diseases, allergic diseases, airway diseases, such as asthma and chronic obstructive pulmonary disease (copd), transplant rejection, cancers e.g.
08/28/14
20140243302
new patent Bridged bicyclic compounds for the treatment of bacterial infections
Novel bridged bicyclic compounds are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antibacterial agents.
08/28/14
20140243301
new patent Chlorobis copper (i) complex compositions and methods of manufacture and use
A method of manufacturing an anhydrous copper complex of formula c12h10cicun2o4 and methods of treating neur-muscular and other diseases, including but not limited to fibromyalgia, multiple sclerosis, muscular dystrophy, rheumatoid arthritis, pain, fatigue, sleeplessness, loss of fine motor control, speech loss, inflexibility, alzheimer's, dementia, amyotrophic lateral sclerosis, depression, lyme disease, lyme disease co-infection, gastroparesis (gp), myopathy, chronic inflammation and/or incontinence. The anhydrous copper complex preferably is administered in a pharmaceutical and/or dietary supplement composition of the invention..
08/28/14
20140243293
new patent Phosphaplatins as neuroprotective agents
The present disclosure provides for compositions for the treatment of neurodegenerative diseases comprising one or more isolated phosphate complexes of platinum and methods of uses thereof for treating neurodegenerative diseases including amyotrophic lateral sclerosis, alzheimer's disease, stroke, epilepsy, parkinsons, huntington's disease and diabetes associated peripheral neuropathy the present disclosure is also directed towards an anti-angiogenic composition useful for inhibiting angiogenesis related to age-related macular degeneration, diabetic retinopathy and tumor-associated angiogenesis. An embodiment of the present disclosure is also directed towards a method for modulating the expression of pigment epithelial derived factor (pedf) gene in an individual in need thereof.
08/28/14
20140243291
new patent Methylphenidate-oxoacid conjugates, processes of making and using the same
The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker.
08/28/14
20140243290
new patent Aminopyrimidines as syk inhibitors
The present invention provides novel pyrimidine amines of formula (i) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, copd and rheumatoid arthritis.. .
08/28/14
20140243289
new patent Prodrugs of modulators of abc transporters
The present invention relates to prodrugs of modulators of abc transporters, particularly, cftr modulators, compositions thereof, and methods therewith. The present invention also relates to methods of treating abc transporter mediated diseases using such modulators..
08/28/14
20140243288
new patent Fused ring-containing oxazolidinones antibiotics
The present invention relates to a fused ring-containing oxazolidinone compound shown by general formula (i), a pharmaceutically acceptable salt thereof and a stereoisomer thereof, wherein r1, r2, r3, r4, r5, r6, a, b and c are as defined in the description. The present invention further relates to a method for preparing the compound, a pharmaceutical composition and a pharmaceutical formulation comprising the compound, and a use of the compound for the manufacture of a medicament for the treatment and/or prevention of infectious diseases and a use for the treatment and/or prevention of infectious diseases..
08/28/14
20140243281
new patent Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases
Provided herein are pediatric dosage forms for use in the treatment of a pediatric cholestatic liver disease by non-systemically administering to an individual in need thereof a therapeutically effective amount of the pediatric dosage form comprising an apical sodium-dependent bile acid transporter inhibitor (asbti) or a pharmaceutically acceptable salt thereof. Also provided are said pediatric dosage form for use in the treatment of a pediatric liver disease, for use in decreasing the levels of serum bile acids or hepatic bile acids, for use in the treatment of pruritis, for use in reducing liver enzymes or bilirubin comprising non-systemically administering to an individual in need thereof a therapeutically effective amount of a pediatric formulation comprising an asbti or a pharmaceutically acceptable salt thereof..
08/28/14
20140243276
new patent Smac mimetic (birinapant) for use in the treatment of proliferative diseases (cancer)
A method of using a smac mimetic and pharmaceutical compositions thereof.. .
08/28/14
20140243275
new patent Galectin-3c combination therapy for human cancer
The present invention provides a novel composition of matter useful for the treatment of neoplastic diseases. The novel composition is synergistic and comprised of galectin-3c in combination with a proteosome inhibitor, the combination having a pharmacologic activity greater than the expected additive effect of its individual components.
08/28/14
20140243273
new patent Methods for treating inflammatory diseases and pharmaceutical combinations useful therefor
The present invention provides method of treating or lessening the severity of a disease selected from spondyloarthropathy, systemic lupus erythematosus, rheumatoid arthritis, or any combination thereof comprising the administration of a compound of formula i and an optional co-therapy (e.g., chemotherapy agent, dmard, or any combination thereof). The present invention also provides a pharmaceutical composition comprising a compound of formula i, a method of manufacturing a pharmaceutical composition comprising a compound of formula i, and a method of administering a pharmaceutical composition comprising a solid form of a compound of formula i..
08/28/14
20140243267
new patent Use of nrf2 inducers to treat epidermolysis bullosa simplex and related diseases
The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application describes compositions and methods of treating a patient suffering from skin blistering comprising the use of phase ii enzyme inducers..
08/28/14
20140243266
new patent Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fibroblast growth factor 19 (fgf19) and/or fibroblast growth factor 21 (fgf21), and variants or fusions of fibroblast growth factor 19 (fgf19) and/or fibroblast growth factor 21 (fgf21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.. .
08/28/14
20140243264
new patent Methods of treatment for retinal diseases
The present invention provides methods of treating a retinal disorder comprising administering an effective amount of a neurotrophic factor to a subject having the retinal disorder. The neurotrophic factors useful in the invention include mesencephalic astrocyte-derived neurotrophic factor (manf) and conserved dopamine neurotrophic factor (cdnf).
08/28/14
20140243261
new patent Method for treating diabetes and fatty liver disese by stimulating cellular metabolism
The present invention is a method of treating various diseases and conditions through administering a substantial caloric load coupled with administration of hormone to stimulate the body to convert that caloric load and increase metabolism in at least some cells. Body functioning converts intracellular adenosine triphosphate (atp) as a part of normal cell function.
08/28/14
20140243222
new patent Multi-spot metal-capped nanostructure array nucleic acid chip for diagnosing of corneal dystrophy and preparation method thereof producing same
A multi-spot metal-capped nanostructure array nucleic acid chip for diagnosing corneal dystrophy, and more particularly to a multi-spot metal-capped nanostructure array nucleic acid chip capable of employing lspr (localized surface plasmon resonance) optical properties, a preparation method thereof, and a multi-spot metal-capped nanostructure array nucleic acid chip for diagnosing bigh3 gene mutations, which can diagnose various corneal dystrophies. The metal-capped nanostructure array nucleic acid chip can be combined with analysis devices, including a light source, a detector, a spectrophotometer and a computer, to provide an lspr optical property-based optical biosensor, and the use of the multi-spot metal-capped nanostructure array nucleic acid chip for diagnosing bigh3 gene mutations allows the simultaneous diagnosis of various corneal dystrophies that are genetic ocular diseases..
08/28/14
20140243215
new patent Method for diagnosing renal diseases or predispositions
The invention provides a method of diagnosing a disease or a predisposition to contract a disease by assaying for mutations of uromodulin (umod) within a test subject or patient. The presence of a mutation in the umod supports a diagnosis of a disease or a predisposition to contract a disease within the patient..


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This listing is a sample listing of patent applications related to Diseases for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Diseases with additional patents listed. Browse our RSS directory or Search for other possible listings.
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