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Dimethyl patents



      
           
This page is updated frequently with new Dimethyl-related patent applications. Subscribe to the Dimethyl RSS feed to automatically get the update: related Dimethyl RSS feeds. RSS updates for this page: Dimethyl RSS RSS


Date/App# patent app List of recent Dimethyl-related patents
01/29/15
20150031683
 Rho kinase inhibitors for use in treating amyotrophic lateral sclerosis patent thumbnailnew patent Rho kinase inhibitors for use in treating amyotrophic lateral sclerosis
The invention relates to a new use of a known rho kinase inhibitor, fasudil or a fasudil derivative selected from hydroy-fasudil or dimethylfasudil, in the treatment of amyotrophic lateral sclerosis (als).. .
Georg-august-universitÄt GÖttingen Stiftung Öffentlichen Rechts, UniversitÄtsmedizin
01/29/15
20150031597
 Novel process for the manufacture of methyl limonitrile patent thumbnailnew patent Novel process for the manufacture of methyl limonitrile
The present invention is directed to a process for the manufacture of methyl limonitrile comprising a mixture of 3,7-dimethyl-2,6-nonadiene nitrile, 3,7-dimethyl-3,6-nonadiene nitrile and 7-methyl-3-methylene-6-nonene nitrile comprising the following steps: a) reacting 6-methyl-5-octen-2-one with cyano acetic acid and removing carbon dioxide and water, wherein the reaction and the removal of carbon dioxide and water are performed in the presence of a base and a co-base in an organic solvent, wherein the base is pyridine, wherein the co-base is 1,4-diamino butane, and wherein the organic solvent is a solvent which forms a heteroazeotrop with water; b) removing the solvent and pyridine of the reaction mixture obtained after having performed step a) or step c) by distillation to obtain a reaction mixture; c) isomerizing the reaction mixture obtained after having performed step a) or step b) to obtain an isomerized reaction mixture; whereby step b) can be performed before or after step c).. .
Dsm Ip Assets B.v.
01/29/15
20150030751
 Method for processing crustaceans to produce low fluoride/low trimethyl amine products thereof patent thumbnailnew patent Method for processing crustaceans to produce low fluoride/low trimethyl amine products thereof
The present invention contemplates the creation of a low fluoride crustacean oil processed from a phospholipid-protein complex (ppc) formed immediately upon a crustacean (i.e., for example, krill) catch. Further, the crustacean oil may also have reduced trimethyl amine and/or trimethyl amino oxide content.
Olympic Seafood As
01/29/15
20150030706
 Use of essential oils, supercritical extracts and aqueous residues generated during a process for obtaining organic extracts from the artemisia absinthium l. plant patent thumbnailnew patent Use of essential oils, supercritical extracts and aqueous residues generated during a process for obtaining organic extracts from the artemisia absinthium l. plant
The present invention starts with a method for obtaining organic extracts of the artemisia absinthium l. Plant, which includes: a methodology phase for producing said plant, an extraction phase during which said essential oil and a non-volatile extract are obtained, and a phase of extracting supercritical extracts with co2, and refers specifically to the use of the essential oil and/or the supercritical extract extracted as fungicides against phytopathogenic fungi.
Universidad De La Laguna
01/29/15
20150029640
 Electrolyte solution for electric double layer capacitors, and electric double layer capacitor patent thumbnailnew patent Electrolyte solution for electric double layer capacitors, and electric double layer capacitor
An electrolytic solution for electric double layer capacitors includes an organic solvent and quaternary ammonium salt dissolved in the organic solvent. The organic solvent consists of sulfolane and chain sulfone.
Panasonic Corporation
01/22/15
20150025252
 Process for the perparation of sunitinib and its acid addition salts thereof patent thumbnailProcess for the perparation of sunitinib and its acid addition salts thereof
The present invention relates to an improved process for the preparation of sunitinb. The process involves the activation of 5-((z)-(5-fluoro-2-oxoindolin-3-ylidene) methyl)-2,4-dimethyl-1h-pyrrole-3carboxylic acid to corresponding suitable carboxylic acid activating group.
Laurus Labs Private Limited
01/22/15
20150025217
 Yield optimization of polycarbonate polyols patent thumbnailYield optimization of polycarbonate polyols
Embodiments of the invention provide for methods of producing a polycarbonate polyol. The method includes charging a vessel with butanediol, charging the vessel with a polymerization catalyst, and adding to the vessel dimethyl carbonate at a rate of at least 2.0 g of dmc per minute per kg of bdo to produce polycarbonate polyol at a polycarbonate polyol yield of at least 80% of a theoretical yield..
Dow Global Technologies Llc
01/22/15
20150024217
 Polymer, process and composition patent thumbnailPolymer, process and composition
There is described an aqueous urethane acrylate copolymer dispersion comprising a) from 10 to 95 wt-% of a polyurethane copolymer, and b) from 5 to 90 wt-% of a polyvinyl copolymer, where vinyl copolymer (b) comprises from 30 parts to 100 parts by weight of biorenewable monomer(s)—such as itaconic acid, itaconate diesters and/or diamides for example dimethyl itaconate (dmi) or dibutyl itaconate (dbi) and where optionally the composition has a residual monomer level of less than 5000 ppm.. .
Dsm Ip Assets B.v.
01/22/15
20150024047
 Pharmaceutical composition and administrations thereof patent thumbnailPharmaceutical composition and administrations thereof
The present invention relates to pharmaceutical compositions containing a solid dispersion of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.. .
Vertex Pharmaceuticals Incorporated
01/22/15
20150024046
 Abuse-proofed oral dosage form patent thumbnailAbuse-proofed oral dosage form
The present invention relates to an abuse-proofed oral dosage form with controlled release of (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol for once daily administration, which comprises the active ingredient and/or one or more of the pharmaceutically acceptable salts thereof (a), at least one synthetic or natural polymer (c), delayed-release auxiliary substances, optionally physiologically acceptable auxiliary substances (b) and optionally a wax (d), component (c) or (d) in each case exhibiting a breaking strength of at least 500 n, preferably of at least 1000 n.. .
GrÜnenthal Gmbh
01/22/15
20150024041

Health supplement using guarana extract


The current invention is a supplement made from a combination of herbs, vitamins, amino acids which in the preferred embodiment is a 100% vegetarian liquid capsules that are ingested allow for rapid absorption. The components of the supplement can be mint or menthol such as peppermint or spearmint, methyl b12 or b12, niacin, guarana, dimethylaminoethanol, acetyl-l-carnitine or alcar, ocimum tenuiflorum, one or more teas such as green tea, white tea or black tea, ginkgo, rhodiola rosea, phosphatidylserine, tyrosine, l-alpha glycerylphosphorylcholine, citicoline (inn), huperzine a, and vinpocetine..
01/22/15
20150023861

Alternative methods for the synthesis of organosilicon compounds


A method of forming chloro-substituted silanes from the reaction of an alkoxysilane with a chlorinating agent in the optional presence of a catalyst is provided. More specifically, chloro-substituted silanes, including but not limited to silicon tetrachloride, are formed by reacting a chlorinating agent, such as thionyl chloride, with an alkylalkoxysilane having the formula (r′o)4-xsirx, where r and r′ are independently selected alkyl groups comprising one or more carbon atoms and x is 0, 1, 2, or 3.
Case Western Reserve University
01/22/15
20150021197

Novel metal complex catalysts and uses thereof


The invention relates to novel metal complexes useful as catalysts in redox reactions (such as, hydrogen (h2) production). In particular, the invention provides novel transition metal (e.g., cobalt (co) or nickel (ni)) complexes, in which the transition metal is coupled with n,n-bis(2-pyridinylmethyl)-2,2′-bipyridine-6-methanamine (dpa-bpy), 6′-((bis(pyridin-2-ylmethyl)amino)methyl)-n,n-dimethyl-2,2′-bipyridin-6-amine (dpa-abpy), n,n-bis((isoquinolin-1-yl)methyl)(6-(pyridin-2-yl)pyridin-2-yl)methanamine (diq-bpy), or a derivative thereof.
University Of Memphis Research Foundation
01/15/15
20150018587

Processes for isolating fluorinated products


Useful processes for isolating the fluorinated products formed by reaction with 4-tert-butyl-2,6-dimethylphenylsulfur trifluoride (fluolead) are disclosed. The processes comprise the conversion of the byproduct (formula i) to sulfinate ester (formula v), and to sulfonate eater (formula vi), and then to the water-soluble sulfonate salt (formula iv) in the presence of the fluorinated products..
Ube Industries, Ltd.
01/15/15
20150018582

Direct dimethyl ether synthesis from synthesis gas


The invention concerns processes for preparing dimethyl ether from synthesis gas, comprising a synthesis step, wherein synthesis gas comprising hydrogen and carbon monoxide is converted into dimethyl ether and carbon dioxide, and a separation step, wherein unconverted synthesis gas is separated from carbon dioxide, wherein unconverted synthesis gas is separated from carbon dioxide by a membrane.. .
Linde Aktiengesellschaft
01/15/15
20150018560

Process for preparing cis-5-[1-(4-chlorophenyl)-methylene]-1-hydroxymethyl-2,2-dimethylcyclopentanol


The invention also relates to processes and intermediates for preparing an epoxy alcohol of formulae (va) or (vb). The invention furthermore relates to processes for preparing cis-metconazole in which a diol of the formulae (ia) or (ib) is applied as a precursor..
01/15/15
20150018548

Process for producing n-methyl or n,n-dimetyl amines


A process for producing n-methyl or n,n-dimethyl amines, which comprises using amine compound, nitro-containing compound or nitrile compound as a starting material, carbon dioxide as a methylating agent and hydrogen gas as a reducing agent, and allowing them to react in a sealed reactor for 6 to 48 h in a reaction medium at a reaction temperature of 80 to 180 ° c. In the presence of a composite catalyst, so as to provide n-methyl or n,n-dimethyl amines.
Lanzhou Institute Of Chemical Physics, Chinese Academy Of Sciences
01/15/15
20150018413

Crystalline solids of a metap-2 inhibitor and methods of making and using same


The disclosure is in part directed to crystalline forms of 6-o-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.. .
Zafgen, Inc.
01/15/15
20150018212

Auxin herbicide composition


An aqueous liquid herbicide composition comprising a solution of at least one of 2,4-d and dicamba in the form of the monomethylamine salt and at least one of 2,4-d and dicamba in the form of the dimethylamine salt wherein the molar ratio of monomethylamine to dimethylamine is in the range of from 1:20 to 4:6.. .
Nufarm Australia Limited
01/15/15
20150017450

Resin composition and semiconductor mounting substrate obtained by molding same


A resin composition which contains at least constituent elements (a)-(e) described below and wherein the epoxy resin (a) contains 80-100% by mass of a bifunctional epoxy resin and component (d) is contained in an amount of 60-85% by mass relative to 100% by mass of the total mass of the resin composition. This resin composition does not substantially contain a solvent and is in a liquid state at room temperature.
Toray Industries, Inc.
01/15/15
20150016857

Liquid cosmetic


Provided is a liquid cosmetic suited for a liquid cosmetic applicator using a brush or a pen feed as an applying means and suited for use in an eyeliner or an eyebrow, which has a good water resistance and is excellent in a skin adhesive property and which is free of a lustrous feeling and has a mat tone. The liquid cosmetic comprises at least carbon black, water, 0.5 to 5% by mass of a dispersant comprising a film-formable resin, 2 to 15% by mass as a solid of a film-forming agent, 0.5% by mass or less of a surfactant, and xanthan gum or a hydroxyethyl acrylate/acryloyldimethyltaurinato na copolymer for a mat tone provider; a glossiness of the liquid cosmetic is 6.5 or less; and a viscosity thereof at 25° c.
Mitsubishi Pencil Company, Limited
01/15/15
20150014727

Silicone-grafted core-shell particles, polymer matrix, and led containing same


A silicone-grafted core-shell particle is described wherein the silicone-grafted core-shell particle comprises a core of an inorganic particle and a shell of a grafted poly(dimethylsiloxane) polymer formed from a bi-terminated poly(dimethylsiloxane) having reactive groups at each terminal end. The silicone-grafted core-shell particles may be dispersed in a polysiloxane polymer matrix and employed as an led encapsulant..
Osram Sylvania Inc.
01/08/15
20150011807

Methods for the production of renewable dimethyl jp10


A highly efficient method for the conversion of a natural product into the high density fuel rj-4 with concomitant evolution of isobutylene for conversion to fuels and polymers, more specifically, embodiments of the invention relate to efficient methods for the conversion of the renewable, linear terpene alcohol, linalool into a drop-in, high density fuel suitable for ramjet or missile propulsion.. .
01/08/15
20150011777

Method for preparing d-biotin


Abstract the invention discloses a d-biotin preparation method. In the prior art, with a synthesis method utilizing malonic acid diester as raw materials, impurities are also produced along with the obtained d-biotin.
Zhejiang Medicine Co., Ltd., Xinchang Pharmaceutical Factory
01/08/15
20150011429

Serum-free freezing medium used in adipose-derived stem cells and establishment of adipose-derived stem cell library


Disclosed is a serum-free freezing medium used in adipose-derived stem cells and a method for establishing an adipose-derived stem cell library. The serum-free freezing medium comprises a serum-free culture medium, dimethyl sulfoxide and a serum substitution component ksr; the defects of unstable freezing quality of the adipose-derived stem cells and influence of harmful factors in serum on the adipose-derived stem cells are solved, and the adipose-derived stem cells stored have the advantages of high survival percentage, well adherence growth and strong differentiation capacity..
Cellular Biomedicine Group (shanghai) Ltd
01/08/15
20150011005

Method for producing cell having nucleic acid introduced therein


A method for producing a cell having nucleic acid introduced therein and having low cytotoxicity is useful in primary cells and slowly dividing cells, for which nucleic acid introduction is difficult with conventional techniques. A method for introducing nucleic acid into a cell includes the steps of mixing a nucleic acid with a temperature sensitive material at a temperature lower than the cloud point of the temperature sensitive material, the temperature sensitive material being formed by adding 2-amino-2-hydroxymethyl-1,3-propanediol to a temperature-sensitive polymer material having 2-n,n-dimethylaminoethyl methacrylate and/or a derivative thereof as the main polymer component, flow coating a culture vessel with the resulting mixed liquid, and culturing a cell suspension provided to the culture vessel at a temperature higher than the cloud point..
National Cerebral And Cardiovascular Center
01/08/15
20150010628

Pharmaceutical composition and administrations thereof


The present invention relates to pharmaceutical compositions containing a solid dispersion of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders and mini-tablets and methods for treating cystic fibrosis employing the pharmaceutical composition.. .
Vertex Pharmaceuticals Incorporated
01/08/15
20150007992

Use of terpolymers as fluid loss additives in well cementing


What is proposed is the use of a terpolymer comprising 5-95 mol % of 2-acrylamido-2-methylpropanesulfonic acid, 5-95 mol % of n,n-dimethylacrylamide and 5-12 mol % of acrylic acid as a fluid loss additive in well cementing.. .
Basf Se
01/01/15
20150005559

Catalyst used in the production of ethylene and propylene from methanol and/or dimethyl ether, preparing the same and using the same


The application provides a catalyst for producing ethylene and propylene from methanol and/or dimethyl ether, and a preparation and application thereof. In the present application, a molecular sieve catalyst co-modified by rare earth metals and silanization is utilized.
Dalian Institute Of Chemical Physics, Chinese Academy Of Sciences
01/01/15
20150005318

1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment


This disclosure relates to a method of treating a disease selected from the group consisting of alzheimer's disease, cognitive impairment, and attention deficit hyperactivity disorder (adhd). The method includes administering a therapeutically effective amount of compound i or a pharmaceutically acceptable salt thereof to patient in need thereof, in which compound i is 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine..
H. Lundbeck A/s
01/01/15
20150005253

Novel combinations for treating acute myeloid leukaemia or chronic myeloid leukaemia


The present disclosure relates to combinations of n-[2-(2,1,3-benzothiadiazol-5-ylamino)-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-n′-(1,1-dimethylethyl)-urea and cytarabine and their use for treating aml or cml.. .
Sanofi
01/01/15
20150005207

Systems and methods for producing dimethyl sulfide from gasified coke


Petroleum coke or coal coke is gasified to produce a gas stream containing carbon monoxide, hydrogen, hydrogen sulfide, and optionally ammonia, carbon dioxide, water, and nitrogen. Carbon monoxide, hydrogen, and hydrogen sulfide, and optionally ammonia, carbon dioxide, water, and nitrogen are separated from the gas stream.
Shell Oil Company
01/01/15
20150005206

High-temperature crosslinked polymer for use in a well


A method comprising the steps of: (a) forming a fluid comprising a crosslinked polymer, wherein the crosslinked polymer comprises: (i) a first monomeric unit of one or more n-vinyl lactams; and (ii) a crosslinker selected from the group consisting of: divinyl ether, diallyl ether, vinyl or allyl ethers of polyglycols or polyols, divinylbenzene, 1,3-divinylimidazolidin-2-one, divinyltetrahydropyrimidin-2(1h)-one, dienes, allyl amines, n-vinyl-3(e)-ethylidene pyrrolidone, ethylidene bis(n-vinylpyrrolidone), and any combination of any of the foregoing; and (b) introducing the fluid into a portion of a well. The crosslinked polymer may additionally comprise: a second monomeric unit selected from the group consisting of: acrylamide, n-substituted acrylamides, methacrylamide, n-substituted methacrylamides, acrylates, methacrylates, acrylic acid, methacrylic acid, n-vinylamides, n-allyl amides, vinyl alcohol, vinyl ethers, vinyl esters, allyl alcohol, allyl ethers, allyl esters, vinylpyridine, vinyl sulfonates, allyl sulfonates, vinylimidazole, allylimidazole, diallyldimethylammonium chloride, and any combination of any of the foregoing..
Halliburton Energy Services, Inc.
01/01/15
20150004648

Reusable pcr amplification system and method


A dna amplification device utilizing a polydimethylsiloxane (pdms) and silicon substrate coated with spin-on glass (sog) is provided. This pdms layer is irreversibly bonded to the sog layer of the silicon substrate using oxygen plasma.
The Curators Of The University Of Missouri
01/01/15
20150000915

Remediation of asphaltene-induced plugging of wellbores and production lines


A method of treating a wellbore penetrating a subterranean formation comprising: providing an asphaltene solvent, wherein the asphaltene solvent comprises at least 75 mol % dimethyl sulfide and introducing the asphaltene solvent into the wellbore. .
Shell Oil Company
01/01/15
20150000907

Systems and methods for producing dimethyl sulfide from sour gas


Dimethyl sulfide is produced from sour gas. The dimethyl sulfide is utilized in an oil recovery formulation introduced into a petroleum-bearing formation to enhance recovery of petroleum from the formation..
Shell Oil Company
12/25/14
20140378711

Method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde


Provided in the present invention is a method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde. The synthesis method comprises the following steps: (1) adding acetaldehyde diethyl acetal and ethyl-(1-propenyl)-ether under the effect of a catalyst to produce 1,1,3-triethoxy-2-methyl-butane; (2) pyrolysis synthesizing 1,1,3-triethoxy-2-methyl-butane under the catalytic effects of isoquinoline and p-toluenesulfonic acid to produce 1-methoxy-2-methyl-1,3-butadiene; (3) dissolving 1-methoxy-2-methyl-1,3-butadiene in anhydrous ethanol solvent for synthesis with a phase transfer catalyst, cetyl-trimethyl ammonium bromide, and a chlorinating agent, trichloroisocyanuric acid, to generate 4,4-diethoxy-3-methyl-1-chloro-butene; (4) combining 4,4-diethoxy-3-methyl-1-chloro-butene with a triphenylphosphine salt to produce a phosphonium salt; and (5) condensing the phosphonium salt under the effects of hydrogen peroxide in conjunction with sodium carbonate solution to generate 1,1,8,8-tetramethyl-2,7-dimethyl-2,4,6-octatriene; then hydrolyzing under acidic conditions to synthesize 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde.
Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
12/25/14
20140378706

Process for the preparation of (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol


The present invention relates to a process for the preparation of (1r,2r)-3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol.. .
Grunenthal Gmbh
12/25/14
20140378695

Novel process for the manufacture of methyl limonitrile


The present invention is directed to a process for the manufacture of methyl limonitrile comprising a mixture of 3,7-dimethyl-2,6-nonadiene nitrile, 3,7-dimethyl-3,6-nonadiene nitrile and 7-methyl-3-methylene-6-nonene nitrile comprising the following steps: a) reacting 6-methyl-5-octen-2-one with cyano acetic acid and removing carbon dioxide and water, wherein the reaction and the removal of carbon dioxide and water are performed in the presence of a base and a co-base 1 in an organic solvent, and wherein the organic solvent is a solvent which forms a heteroazeotrop with water; b) removing the solvent and the base of the reaction mixture obtained after having performed step a) or step c) by distillation to obtain a reaction mixture, whereby this step may optionally be performed in the presence of a co-base 2; c) isomerizing the reaction mixture obtained after having performed step a) or step b) to obtain an isomerized reaction mixture in the presence of a co-base 2; whereby step b) can be performed before or after step c).. .
Dsm Ip Assets B.v.
12/25/14
20140378644

Methods for preparation of macrocyclic polyester oligomer via heterogeneous catalysis


The invention relates to methods and systems for preparing macrocyclic polyester oligomer (mpo) directly from monomer via heterogeneous catalysis, rather than by depolymerizing a polyester. For example, in an exemplary embodiment, cyclic poly(butylene terephthalate) (cpbt) is produced by reacting butanediol (bdo) and dimethylterephthalate (dmt) in an organic solvent—for example, ortho-dichlorobenzene (odcb).
Liquid Thermo Plastics, Inc.
12/25/14
20140378542

Cocrystals of dimethyl fumarate


Disclosed herein are cocrystals of dimethyl fumarate, which is a prodrug of methyl hydrogen fumarate.. .
Xenoport, Inc.
12/25/14
20140378509

Pyrazolone derivatives as pde4 inhibitors


The compound 1-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1h-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione is a novel effective inhibitor of the type 4 phosphodiesterase useful in the treatment of psoriasis or atopic dermatitis.. .
Takeda Gmbh
12/25/14
20140377542

Plate with titanium dioxide on its surface, manufacturing process and uses thereof


A plate with titanium dioxide on its surface, as well as its manufacturing process and uses thereof are provided. The plate comprises (a) a substrate; (b) a polydimethylsiloxane (pdms) layer on at least one surface of the substrate; and (c) one or more aggregations of titanium dioxide particles on the polydimethylsiloxane layer.
China Medical University
12/25/14
20140377363

1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment


This disclosure relates to a method of treating a disease selected from the group consisting of affective disorders, depression, major depressive disorder, anxiety, general anxiety disorder, social anxiety disorder, obsessive compulsive disorder, panic disorder, and panic attacks. The method includes administering a therapeutically effective amount of compound i or a pharmaceutically acceptable salt thereof to a patient in need thereof, in which compound i is 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine..
H. Lundbeck A/s
12/25/14
20140377330

Bioactive hydrogel


The invention relates to a bioactive hydrogel as a hybrid material of heparin and star-branched polyethylene glycol with functionalized end groups, wherein the heparin is bound directly by reaction of the carboxyl groups activated with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimides/n-hydroxysulfosuccinimide (edc/s-nhs) with the terminal amino groups of the polyethylene glycol covalently by amide bonds.. .
Zetascience Gmbh
12/25/14
20140377304

Treatment and composition for achieving skin anti-aging benefits by corneum protease activation


Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as n,n,-dimethyldodecyl amine oxide (dmdao), an anionic surfactant such as sodium dodecyl sulfate (sds), or monoalkyl phosphate (map) and a chelating agent such as ethylene diamine tetraacetate (edta) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation.
Mary Kay Inc.
12/25/14
20140377214

Materials and methods to enhance hematopoietic stem cells engraftment procedures


This disclosure is directed to the methods of enhancing hematopoietic stem cells (hspc) and progenitor cell (hspc) engraftment procedure. Treatment in vivo of a hspc donor with compounds that reduce pge2 biosynthesis or pge2 receptor antagonists alone, or in combination with other hematopoietic mobilization agents such as amd3100 and g-csf, increases the circulation of available hspcs.
Indiana University Research And Technology Corp.
12/25/14
20140373484

Corona treated polyethylene films


A process for improving the sealing characteristics of corona treated polyolefin films through the use of a stabilizer system comprising i) 1,3,5-tris(4-tert-butyl-3-hydroxy-2,6-dimethyl benzyl)-1,3,5-triazine-2,4,6-(1h,3h,5h)-trione (cas registry number 040601-76-1) and ii) an organic phosphite or phosphonite.. .
Nova Chemicals (international) S.a.
12/18/14
20140371453

1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment


This disclosure relates to a process for the preparation of 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine or a salt thereof.. .
H. Lundbeck A/s
12/18/14
20140371451

Preparation of 3,5-dioxo hexanoate ester in two steps


The invention discloses a method for the preparation of tert-butyl 6-chloro-3,5-dioxohexanoate from meldrum's acid derivative and its use for the preparation of tert-butyl (4r,6s)-(6-hydroxymethyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate (bha), rosuvastatin and atorvastatin.. .
Lonza Ltd
12/18/14
20140371114

Far field diversion technique for treating subterranean formation


Diverting compositions for treating a subterranean zone substantially distanced from a wellbore, comprising: a carrier fluid; and a particulate, partially dehydrated or anhydrous borate source material that does not substantially swell when placed in contact with the carrier fluid. The carrier fluid is capable of carrying and placing the borate source material into a stimulation network substantially distanced from a wellbore, and wherein the borate source material is dissolvable through sufficient contact with an aqueous fluid.
Halliburton Energy Services, Inc.
12/18/14
20140369886

Water treatment


An apparatus and a method of extending a use life of a body of recreational water while reducing a concentration of chlorine required to effectively sanitize the body of recreational water, the method comprising the steps of adding a sanitizing concentration of total available chlorine to the body of recreation water that is suitable for human partial immersion in the body of recreation water; adding a source of silver ions and a source of 1,3-dichloro-5,5-dimethylhydantoin to the body of recreational water to lower the concentration of chlorine required to effectively sanitize the body of recreational water; and maintaining a concentration of silver ions and a concentration of the source of 1,3-dichloro-5,5-dimethylhydantoin effective at extending the use life of the body of recreational by at least 2 folds before a required chlorine shocking of the recreational body of water.. .
12/18/14
20140367734

Light emitting diode


The present invention relates to an encapsulant for ultraviolet light emitting diodes. It is an object of the present invention to provide an encapsulant for uv leds emitting below 350 nm resulting in an increased extraction efficiency of the led.
Forschungsverbund Berlin E.v.
12/18/14
20140367097

Oil recovery system and method


A system and process are provided for recovering oil from an oil-bearing formation. An oil recovery formulation that is first contact miscible with a liquid petroleum composition that is comprised of at least 15 mol % dimethyl sulfide is introduced together with steam or hot water into a subterranean oil-bearing formation comprising heavy oil, extra heavy oil, or bitumen, and oil is produced from the formation..
Shell Oil Company
12/11/14
20140364654

Dimethyl ether (dme) production process


Disclosed herein is a process for monetization of natural gas by producing fuel grade dimethyl ether (dme). The process includes three reactive stages with the first reactive stage being the conversion of natural gas into syngas, the second reactive stage being the conversion of syngas into crude methanol and the third reactive stage being the production of fuel grade dimethyl ether.
12/11/14
20140364651

Method for synthesizing polyoxymethylene dimethyl ethers


The present invention relates to the field of chemical engineering and technology, in particular relates to the sub-field of synthesis of high quality alternative liquid engine fuel from non-petroleum based feedstock, more particularly relates to a method for regulating and optimizing the synthetic process of polyoxymethylene dimethyl ethers utilizing chemical thermodynamic principle. The process of the present invention is achieved by conditions wherein the initial temperature of reaction is controlled at 100-120° c., then the temperature is reduced to 50-70° c.
12/11/14
20140364612

Industrial process for the preparation of buprenorphine and its intermediates


There is provided an efficient industrial process for the preparation of 21-cyclopropyl-7α-(2-hydroxy-3,3-dimethyl-2-butyl)-6,14-endo-ethano-6,7,8,14-tetrahydro-oripavine, i.e. Buprenorphine of formula-i in high yield and purity, with enhanced safety and eco-friendly norms.
12/11/14
20140363717

Low viscosity/high conductivity sodium haloaluminate electrolyte


An additive that is added to the naalx4 electrolyte for use in a zebra battery (or other similar battery). This additive has a moiety with a partial positive charge (δ+) that attracts the negative charge of the [alx4]− moiety and weakens the ionic bond between the na+ and [alx4]− moieties, thereby freeing some na+ ions to transport (move).
12/11/14
20140362239

Surface adhering lens


A lens structure includes an elastomer formed as a lens. The lens has a planar surface and a curved surface opposed to the planar surface.
12/11/14
20140360727

Remediation of asphaltene-induced plugging of an oil-bearing formation


A system and method for remediation of asphaltene-induced fouling of an oil-bearing formation is provided wherein an asphaltene solvent comprising at least 75 mol % dimethyl sulfide is introduced into an oil-bearing formation containing asphaltene deposits and the dimethyl sulfide is contacted with the asphaltene deposits.. .
12/11/14
20140360719

Enhanced oil recovery method


A method for producing oil from a fractured oil bearing formation is provided in which an oil recovery formulation comprising water and dimethyl ether is introduced into a fracture in the formation to mobilize oil, the mobilized oil is contacted with water or brine, and the mobilized oil is produced from the formation at a location positioned upwards from the fracture.. .


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Dimethyl topics: Physiologic, Hydrochloric Acid, Fresnel Zone, Aberration, Ophthalmic, Liquid Crystal, Imaging System, Pharmaceutically Acceptable Salt, Pharmaceutically Acceptable Salts, Chloric Acid, Tartaric Acid, Fumaric Acid, Antagonist, Bradykinin, Enantiomer

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