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Dimethyl patents



      
           
This page is updated frequently with new Dimethyl-related patent applications. Subscribe to the Dimethyl RSS feed to automatically get the update: related Dimethyl RSS feeds. RSS updates for this page: Dimethyl RSS RSS


Date/App# patent app List of recent Dimethyl-related patents
02/26/15
20150057453
 Method for preparation of medetomidine patent thumbnailMethod for preparation of medetomidine
The invention discloses a method for the preparation of medetomidine starting from 1-bromo 2,3-dimethylbenzene and aceton.. .
Lonza Ltd
02/26/15
20150057375
 Use of improved n-alkyl pyrrolidone solvent patent thumbnailUse of improved n-alkyl pyrrolidone solvent
The present invention is concerned with the use of pyrrolidones selected from the group consisting of n-n-butylpyrrolidone, n-isobutylpyrrolidone, n-t-butylpyrrolidone, n-n-pentylpyrrolidone, n-(methyl-substituted butyl)pyrrolidones, ring-methyl-substituted n-propyl and n-butyl pyrrolidones and n-(methoxypropyl) pyrrolidone as replacement solvents in specific applications wherein n-methylpyrrolidone (nmp), n-ethyl-2-pyrrolidone (nep), n,n-dimethyl acetamide (dmac), and/or dimethyl formamide (dmf) is the appropriate solvent to be used. The invention is also concerned with a solvent comprising nmp, nep, dmac, or dmf and one or more pyrrolidones selected from said group, as well as a solvent comprising a second solvent, which is a replacement solvent for nmp, nep, dmac, or dmf and one or more selected from said group..
Taminco
02/26/15
20150056822
 Compositions and methods using same for flowable oxide deposition patent thumbnailCompositions and methods using same for flowable oxide deposition
Described herein are compositions or formulations for forming a film in a semiconductor deposition process, such as without limitation, a flowable chemical vapor deposition of silicon oxide. Also described herein is a method to improve the surface wetting by incorporating an acetylenic alcohol or diol surfactant such as without limitation 3,5-dimethyl-1-hexyn-3-ol, 2,4,7,9-tetramethyl-5-decyn-4,7-diol, 4-ethyl-1-octyn-3-ol, and 2,5-dimethylhexan-2,5-diol, and other related compounds..
Air Products And Chemicals, Inc.
02/26/15
20150053901
 Fluorine-containing phosphate ester-amide, and flame retardant resin, flame retardant liquid and flame retardant solvent for organic synthesis containing same patent thumbnailFluorine-containing phosphate ester-amide, and flame retardant resin, flame retardant liquid and flame retardant solvent for organic synthesis containing same
[solution] a fluorine-containing phosphate ester-amide represented by general formula (1). (in the formula, r1 and r2 are the same or different and represent a branched or linear alkyl group having 1 to 20 carbon atoms in which at least one carbon bonded to a nitrogen atom is a secondary or tertiary carbon, wherein r1 and r2 may have a substituent group selected from the group consisting of an alkoxy group, a hydroxy group, an amino group, a methyl amino group, an ethyl amino group, a dimethyl amino group, diethyl amino group and a fluorine atom.
02/19/15
20150051424
 Method of producing trimethylsulfoxonium bromide and a  temperature control of reaction system producing trimethylsulfoxonium bromide patent thumbnailMethod of producing trimethylsulfoxonium bromide and a temperature control of reaction system producing trimethylsulfoxonium bromide
The present invention relates to a method of producing trimethylsulfoxonium bromide by reacting dimethyl sulfoxide with methyl bromide (mebr), wherein mebr is added in a manner that satisfies conditions (1) and (2): (1) mebr is added at an addition rate that complies with a predetermined feeding profile, (2) mebr is added upon the temperature in the reaction system reaching a predetermined maximum temperature.. .
Kureha Corporation
02/19/15
20150051420
 Esterification process patent thumbnailEsterification process
Embodiments of an invention disclosed herein relate to methods to produce terephthalate esters, the methods include esterifying at least one c6-c13 alcohol with dimethyl terephthalate (dmt) in the presence of a catalyst to produce the terephthalate esters.. .
Exxonmobil Chemical Patents Inc.
02/19/15
20150047849
 Flow back aids patent thumbnailFlow back aids
The present invention discloses liquid quaternary ammonium salts that can be used to treat and coat the surfaces of the proppant sand or inorganic particles that are used in down-hole oil well fracturing operations as well as the containment structure and that these treated surfaces will cause water and oils to flow faster through the porous structure. These liquid quaternary ammonium salts can be chosen from a list that includes but is not limited to cocobis(2-hydroxyethyl)ethylammonium ethyl sulfate, benzylcocobis(hydroxyethyl)ammonium 2-ethyl-hexylsulfate, dibenzylcocobishydroxyethyl ammonium phenolsulfonate, didecyldimethyl-ammonium dodecylbenzenesulfonate and tallow-bis(2-hydroxyethyl)ethylammonium ethyl sulfate..
02/19/15
20150047665
 Hair care compositions with enhanced color retention and methods of preparation therefor patent thumbnailHair care compositions with enhanced color retention and methods of preparation therefor
Hair care compositions, such as shampoo and conditioner compositions, for use with color-treated hair. The compositions when used, for example, to shampoo or condition color-treated hair, being effective to protect color-treated hair such that, for example, there is minimal adverse effect on the color of the color-treated hair, such as fading.
Framkat Lp
02/12/15
20150045571
 Method for preparing an organofunctional compound patent thumbnailMethod for preparing an organofunctional compound
Claimed is a method for making an organofunctional compound of formula rbmcxd comprising the following steps: (i) contacting a transition metal catalyst with a mixture including hydrogen gas and a halide of formula mxa to form a m-containing transition metal catalyst; (ii) contacting the m-containing transition metal catalyst with an organohalide to form the organofunctional compound of formula r mcxd. In the above formulae, m is an element selected from antimony, arsenic, bismuth, boron, cadmium, gallium, germanium, indium, lead, mercury, phosphorus, selenium, sulfur, tellurium, and tin.
Dow Corning Corporation
02/12/15
20150045504
 Release sheet patent thumbnailRelease sheet
A release sheet comprising a base material and a release agent layer formed on at least one surface of the base material by using a release agent composition; the release agent composition contains a first polydimethylsiloxane having at least two alkenyl groups in one molecule and a second polydimethylsiloxane having at least two hydrosilyl groups in one molecule; the release agent composition contains 0.40 to 5.25 mmol of the alkenyl groups and 7.00 to 120.00 mmol of the hydrosilyl groups in a total of 30 g of the first polydimethylsiloxane and the second polydimethylsiloxane; and a molar ratio (b/a) of the hydrosilyl groups (b) to the alkenyl groups (a) is 3.0 to 70.0. Consequently, it is possible to suppress the peeling force from increasing even when the release agent layer of the release sheet is exposed to the air for a long time..
Lintec Corporation
02/12/15
20150045456

Method for producing dimethyl ether from methane


The invention relates to processes for production of dimethyl ether from methane or natural gas comprising: a dry-reforming step, wherein methane and carbon dioxide are converted into carbon monoxide and hydrogen, and a dme synthesis step, wherein the carbon monoxide and hydrogen formed in the dry-reforming step are converted into dimethyl ether, wherein the dry-reforming step and the synthesis step are carried out at identical pressures or at pressures, which do not differ more than 3 bar, preferably not more than 1 bar.. .
Linde Aktiengesellschaft
02/12/15
20150045441

Crystalline diacylhydrazine and the use thereof


The present disclosure provides crystalline polymorphic and amorphous forms of (r)-3,5-dimethyl-benzoic acid n-(1-tert-butyl-butyl)-n′-(2-ethyl-3-methoxy-benzoyl)-hydrazide (compound 1) or (s)-3,5-dimethyl-benzoic acid n-(1-tert-butyl-butyl)-n′-(2-ethyl-3-methoxy-benzoyl)-hydrazide (compound 2). The present disclosure further provides compositions comprising crystalline polymorphic and amorphous forms of compound 1 or compound 2 and an excipient, methods of making crystalline polymorphic or amorphous forms of compound 1 or compound 2, and methods of using crystalline polymorphic or amorphous forms of compound 1 or compound 2 to regulate gene expression in a cell or in a subject..
Intrexon Corporation
02/12/15
20150045223

Biocidal compositions and their use in the control of microorganisms in aqueous and water containing systems


Poly[oxyethylene(dimethyliminio)-ethylene(dimethyliminio)-ethylene)dichloride]. The synergist may be selected from the group consisting of triethanolamine, diethanolamine, ethanolamine, ethanol, and triethylamine.
02/12/15
20150044839

Photoresist stripping and cleaning composition, its preparation and its use


A photoresist stripping and cleaning composition free from n-alkylpyrrolidones and added quaternary ammonium hydroxides comprising a component (a) which comprises the polar organic solvents n-methylimidazole, dimethylsulfoxide and 1-aminopropane-2-ol.. .
Basf Se
02/12/15
20150044747

Methods for increasing production of 3-methyl-2-butenol using fusion proteins


The invention relates, in part, to nucleic acid constructs, genetically modified host cells and methods employing such constructs and host cells to increase the production of 3-methyl-2-butenol from ipp. Thus, in some aspects, the invention provides a genetically modified host cell transformed with a nucleic acid construct encoding a fusion protein comprising a phosphatase capable of catalyzing the dephosphorylation of dimethylallyl diphosphate (dmapp) linked to an ipp isomerase capable of converting ipp to dmapp, wherein the nucleic acid construct is operably linked to a promoter.
The Regents Of The University Of California
02/12/15
20150044133

Preparation of high-silica cha-type molecular sieves using a mixed template


Cha-type molecular sieves are prepared using a n,n,n-trimethyl-1-adamantammonium cation structure directing agent in conjunction with a n,n-dimethyl-3,5-dimethylpiperidinium cation structure directing agent.. .
02/05/15
20150038928

Articles comprising malodor reduction compositions


An absorbent article comprising a malodor reduction composition. The malodor reduction composition comprises a perfume mixture comprising about 5% to about 100%, by weight of said perfume mixture, of at least two perfume materials selected from the group consisting of terpinyl acetate, methyl iso-eugenol, phenyl acetaldehyde dimethyl acetal, and patchone..
The Procter & Gamble Company
02/05/15
20150038745

Cooled reactor for the production of dimethyl ether from methanol


A cooled reactor for the production of dimethyl ether by catalytic dehydration of methanol in the gas phase, the reactor having an adiabatic catalyst bed as starting zone, a moderator zone cooled by direct or indirect heat exchange, and optionally an adiabatic catalyst bed as conditioning zone. The conversion of methanol to dimethyl ether is increased and the formation of undesired by-products is decreased..
L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude
02/05/15
20150038667

Poly(phenylene ether) copolymer and making


A poly(phenylene ether) copolymer comprising about 5 to 40 mole percent repeat units derived from 2-phenylphenol and 60 to about 95 mole percent repeat units derived from 2,6-dimethylphenol, wherein the poly(phenylene ether) copolymer has a weight average molecular weight of at least 8,000 atomic mass units, is disclosed. Also disclosed is a method of preparing the poly(phenylene ether) copolymer, the method comprising oxidatively copolymerizing a monomer mixture comprising about 5 to 40 mole percent 2-phenylphenol and about 60 to about 95 mole percent 2,6-dimethylphenol in the presence of a solvent, molecular oxygen, and a polymerization catalyst comprising a metal ion and at least one amine ligand to form a solution of the poly(phenylene ether) copolymer in the solvent, wherein a ratio of total moles of 2-phenylphenol and 2,6-dimethylphenol to moles of metal ion is about 10:1 to about 1200:1..
Sabic Innovative Plastics Ip B.v.
02/05/15
20150038429

Etoposide and doxorubicin conjugates for drug delivery


The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides having a hydrolyzable covalent bond to a therapeutic agent that includes, etoposide, etoposide 4′-dimethylglycine or doxorubicin.
Angiochem Inc.
02/05/15
20150037690

Electrolytes for stable cycling of high capacity lithium based batteries


Electrolytes are described with additives that provide good shelf life with improved cycling stability properties. The electrolytes can provide appropriate high voltage stability for high capacity positive electrode active materials.
Envia Systems, Inc.
01/29/15
20150031683

Rho kinase inhibitors for use in treating amyotrophic lateral sclerosis


The invention relates to a new use of a known rho kinase inhibitor, fasudil or a fasudil derivative selected from hydroy-fasudil or dimethylfasudil, in the treatment of amyotrophic lateral sclerosis (als).. .
Georg-august-universitÄt GÖttingen Stiftung Öffentlichen Rechts, UniversitÄtsmedizin
01/29/15
20150031597

Novel process for the manufacture of methyl limonitrile


The present invention is directed to a process for the manufacture of methyl limonitrile comprising a mixture of 3,7-dimethyl-2,6-nonadiene nitrile, 3,7-dimethyl-3,6-nonadiene nitrile and 7-methyl-3-methylene-6-nonene nitrile comprising the following steps: a) reacting 6-methyl-5-octen-2-one with cyano acetic acid and removing carbon dioxide and water, wherein the reaction and the removal of carbon dioxide and water are performed in the presence of a base and a co-base in an organic solvent, wherein the base is pyridine, wherein the co-base is 1,4-diamino butane, and wherein the organic solvent is a solvent which forms a heteroazeotrop with water; b) removing the solvent and pyridine of the reaction mixture obtained after having performed step a) or step c) by distillation to obtain a reaction mixture; c) isomerizing the reaction mixture obtained after having performed step a) or step b) to obtain an isomerized reaction mixture; whereby step b) can be performed before or after step c).. .
Dsm Ip Assets B.v.
01/29/15
20150030751

Method for processing crustaceans to produce low fluoride/low trimethyl amine products thereof


The present invention contemplates the creation of a low fluoride crustacean oil processed from a phospholipid-protein complex (ppc) formed immediately upon a crustacean (i.e., for example, krill) catch. Further, the crustacean oil may also have reduced trimethyl amine and/or trimethyl amino oxide content.
Olympic Seafood As
01/29/15
20150030706

Use of essential oils, supercritical extracts and aqueous residues generated during a process for obtaining organic extracts from the artemisia absinthium l. plant


The present invention starts with a method for obtaining organic extracts of the artemisia absinthium l. Plant, which includes: a methodology phase for producing said plant, an extraction phase during which said essential oil and a non-volatile extract are obtained, and a phase of extracting supercritical extracts with co2, and refers specifically to the use of the essential oil and/or the supercritical extract extracted as fungicides against phytopathogenic fungi.
Universidad De La Laguna
01/29/15
20150029640

Electrolyte solution for electric double layer capacitors, and electric double layer capacitor


An electrolytic solution for electric double layer capacitors includes an organic solvent and quaternary ammonium salt dissolved in the organic solvent. The organic solvent consists of sulfolane and chain sulfone.
Panasonic Corporation
01/22/15
20150025252

Process for the perparation of sunitinib and its acid addition salts thereof


The present invention relates to an improved process for the preparation of sunitinb. The process involves the activation of 5-((z)-(5-fluoro-2-oxoindolin-3-ylidene) methyl)-2,4-dimethyl-1h-pyrrole-3carboxylic acid to corresponding suitable carboxylic acid activating group.
Laurus Labs Private Limited
01/22/15
20150025217

Yield optimization of polycarbonate polyols


Embodiments of the invention provide for methods of producing a polycarbonate polyol. The method includes charging a vessel with butanediol, charging the vessel with a polymerization catalyst, and adding to the vessel dimethyl carbonate at a rate of at least 2.0 g of dmc per minute per kg of bdo to produce polycarbonate polyol at a polycarbonate polyol yield of at least 80% of a theoretical yield..
Dow Global Technologies Llc
01/22/15
20150024217

Polymer, process and composition


There is described an aqueous urethane acrylate copolymer dispersion comprising a) from 10 to 95 wt-% of a polyurethane copolymer, and b) from 5 to 90 wt-% of a polyvinyl copolymer, where vinyl copolymer (b) comprises from 30 parts to 100 parts by weight of biorenewable monomer(s)—such as itaconic acid, itaconate diesters and/or diamides for example dimethyl itaconate (dmi) or dibutyl itaconate (dbi) and where optionally the composition has a residual monomer level of less than 5000 ppm.. .
Dsm Ip Assets B.v.
01/22/15
20150024047

Pharmaceutical composition and administrations thereof


The present invention relates to pharmaceutical compositions containing a solid dispersion of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.. .
Vertex Pharmaceuticals Incorporated
01/22/15
20150024046

Abuse-proofed oral dosage form


The present invention relates to an abuse-proofed oral dosage form with controlled release of (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol for once daily administration, which comprises the active ingredient and/or one or more of the pharmaceutically acceptable salts thereof (a), at least one synthetic or natural polymer (c), delayed-release auxiliary substances, optionally physiologically acceptable auxiliary substances (b) and optionally a wax (d), component (c) or (d) in each case exhibiting a breaking strength of at least 500 n, preferably of at least 1000 n.. .
GrÜnenthal Gmbh
01/22/15
20150024041

Health supplement using guarana extract


The current invention is a supplement made from a combination of herbs, vitamins, amino acids which in the preferred embodiment is a 100% vegetarian liquid capsules that are ingested allow for rapid absorption. The components of the supplement can be mint or menthol such as peppermint or spearmint, methyl b12 or b12, niacin, guarana, dimethylaminoethanol, acetyl-l-carnitine or alcar, ocimum tenuiflorum, one or more teas such as green tea, white tea or black tea, ginkgo, rhodiola rosea, phosphatidylserine, tyrosine, l-alpha glycerylphosphorylcholine, citicoline (inn), huperzine a, and vinpocetine..
01/22/15
20150023861

Alternative methods for the synthesis of organosilicon compounds


A method of forming chloro-substituted silanes from the reaction of an alkoxysilane with a chlorinating agent in the optional presence of a catalyst is provided. More specifically, chloro-substituted silanes, including but not limited to silicon tetrachloride, are formed by reacting a chlorinating agent, such as thionyl chloride, with an alkylalkoxysilane having the formula (r′o)4-xsirx, where r and r′ are independently selected alkyl groups comprising one or more carbon atoms and x is 0, 1, 2, or 3.
Case Western Reserve University
01/22/15
20150021197

Novel metal complex catalysts and uses thereof


The invention relates to novel metal complexes useful as catalysts in redox reactions (such as, hydrogen (h2) production). In particular, the invention provides novel transition metal (e.g., cobalt (co) or nickel (ni)) complexes, in which the transition metal is coupled with n,n-bis(2-pyridinylmethyl)-2,2′-bipyridine-6-methanamine (dpa-bpy), 6′-((bis(pyridin-2-ylmethyl)amino)methyl)-n,n-dimethyl-2,2′-bipyridin-6-amine (dpa-abpy), n,n-bis((isoquinolin-1-yl)methyl)(6-(pyridin-2-yl)pyridin-2-yl)methanamine (diq-bpy), or a derivative thereof.
University Of Memphis Research Foundation
01/15/15
20150018587

Processes for isolating fluorinated products


Useful processes for isolating the fluorinated products formed by reaction with 4-tert-butyl-2,6-dimethylphenylsulfur trifluoride (fluolead) are disclosed. The processes comprise the conversion of the byproduct (formula i) to sulfinate ester (formula v), and to sulfonate eater (formula vi), and then to the water-soluble sulfonate salt (formula iv) in the presence of the fluorinated products..
Ube Industries, Ltd.
01/15/15
20150018582

Direct dimethyl ether synthesis from synthesis gas


The invention concerns processes for preparing dimethyl ether from synthesis gas, comprising a synthesis step, wherein synthesis gas comprising hydrogen and carbon monoxide is converted into dimethyl ether and carbon dioxide, and a separation step, wherein unconverted synthesis gas is separated from carbon dioxide, wherein unconverted synthesis gas is separated from carbon dioxide by a membrane.. .
Linde Aktiengesellschaft
01/15/15
20150018560

Process for preparing cis-5-[1-(4-chlorophenyl)-methylene]-1-hydroxymethyl-2,2-dimethylcyclopentanol


The invention also relates to processes and intermediates for preparing an epoxy alcohol of formulae (va) or (vb). The invention furthermore relates to processes for preparing cis-metconazole in which a diol of the formulae (ia) or (ib) is applied as a precursor..
01/15/15
20150018548

Process for producing n-methyl or n,n-dimetyl amines


A process for producing n-methyl or n,n-dimethyl amines, which comprises using amine compound, nitro-containing compound or nitrile compound as a starting material, carbon dioxide as a methylating agent and hydrogen gas as a reducing agent, and allowing them to react in a sealed reactor for 6 to 48 h in a reaction medium at a reaction temperature of 80 to 180 ° c. In the presence of a composite catalyst, so as to provide n-methyl or n,n-dimethyl amines.
Lanzhou Institute Of Chemical Physics, Chinese Academy Of Sciences
01/15/15
20150018413

Crystalline solids of a metap-2 inhibitor and methods of making and using same


The disclosure is in part directed to crystalline forms of 6-o-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.. .
Zafgen, Inc.
01/15/15
20150018212

Auxin herbicide composition


An aqueous liquid herbicide composition comprising a solution of at least one of 2,4-d and dicamba in the form of the monomethylamine salt and at least one of 2,4-d and dicamba in the form of the dimethylamine salt wherein the molar ratio of monomethylamine to dimethylamine is in the range of from 1:20 to 4:6.. .
Nufarm Australia Limited
01/15/15
20150017450

Resin composition and semiconductor mounting substrate obtained by molding same


A resin composition which contains at least constituent elements (a)-(e) described below and wherein the epoxy resin (a) contains 80-100% by mass of a bifunctional epoxy resin and component (d) is contained in an amount of 60-85% by mass relative to 100% by mass of the total mass of the resin composition. This resin composition does not substantially contain a solvent and is in a liquid state at room temperature.
Toray Industries, Inc.
01/15/15
20150016857

Liquid cosmetic


Provided is a liquid cosmetic suited for a liquid cosmetic applicator using a brush or a pen feed as an applying means and suited for use in an eyeliner or an eyebrow, which has a good water resistance and is excellent in a skin adhesive property and which is free of a lustrous feeling and has a mat tone. The liquid cosmetic comprises at least carbon black, water, 0.5 to 5% by mass of a dispersant comprising a film-formable resin, 2 to 15% by mass as a solid of a film-forming agent, 0.5% by mass or less of a surfactant, and xanthan gum or a hydroxyethyl acrylate/acryloyldimethyltaurinato na copolymer for a mat tone provider; a glossiness of the liquid cosmetic is 6.5 or less; and a viscosity thereof at 25° c.
Mitsubishi Pencil Company, Limited
01/15/15
20150014727

Silicone-grafted core-shell particles, polymer matrix, and led containing same


A silicone-grafted core-shell particle is described wherein the silicone-grafted core-shell particle comprises a core of an inorganic particle and a shell of a grafted poly(dimethylsiloxane) polymer formed from a bi-terminated poly(dimethylsiloxane) having reactive groups at each terminal end. The silicone-grafted core-shell particles may be dispersed in a polysiloxane polymer matrix and employed as an led encapsulant..
Osram Sylvania Inc.
01/08/15
20150011807

Methods for the production of renewable dimethyl jp10


A highly efficient method for the conversion of a natural product into the high density fuel rj-4 with concomitant evolution of isobutylene for conversion to fuels and polymers, more specifically, embodiments of the invention relate to efficient methods for the conversion of the renewable, linear terpene alcohol, linalool into a drop-in, high density fuel suitable for ramjet or missile propulsion.. .
01/08/15
20150011777

Method for preparing d-biotin


Abstract the invention discloses a d-biotin preparation method. In the prior art, with a synthesis method utilizing malonic acid diester as raw materials, impurities are also produced along with the obtained d-biotin.
Zhejiang Medicine Co., Ltd., Xinchang Pharmaceutical Factory
01/08/15
20150011429

Serum-free freezing medium used in adipose-derived stem cells and establishment of adipose-derived stem cell library


Disclosed is a serum-free freezing medium used in adipose-derived stem cells and a method for establishing an adipose-derived stem cell library. The serum-free freezing medium comprises a serum-free culture medium, dimethyl sulfoxide and a serum substitution component ksr; the defects of unstable freezing quality of the adipose-derived stem cells and influence of harmful factors in serum on the adipose-derived stem cells are solved, and the adipose-derived stem cells stored have the advantages of high survival percentage, well adherence growth and strong differentiation capacity..
Cellular Biomedicine Group (shanghai) Ltd
01/08/15
20150011005

Method for producing cell having nucleic acid introduced therein


A method for producing a cell having nucleic acid introduced therein and having low cytotoxicity is useful in primary cells and slowly dividing cells, for which nucleic acid introduction is difficult with conventional techniques. A method for introducing nucleic acid into a cell includes the steps of mixing a nucleic acid with a temperature sensitive material at a temperature lower than the cloud point of the temperature sensitive material, the temperature sensitive material being formed by adding 2-amino-2-hydroxymethyl-1,3-propanediol to a temperature-sensitive polymer material having 2-n,n-dimethylaminoethyl methacrylate and/or a derivative thereof as the main polymer component, flow coating a culture vessel with the resulting mixed liquid, and culturing a cell suspension provided to the culture vessel at a temperature higher than the cloud point..
National Cerebral And Cardiovascular Center
01/08/15
20150010628

Pharmaceutical composition and administrations thereof


The present invention relates to pharmaceutical compositions containing a solid dispersion of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders and mini-tablets and methods for treating cystic fibrosis employing the pharmaceutical composition.. .
Vertex Pharmaceuticals Incorporated
01/08/15
20150007992

Use of terpolymers as fluid loss additives in well cementing


What is proposed is the use of a terpolymer comprising 5-95 mol % of 2-acrylamido-2-methylpropanesulfonic acid, 5-95 mol % of n,n-dimethylacrylamide and 5-12 mol % of acrylic acid as a fluid loss additive in well cementing.. .
Basf Se
01/01/15
20150005559

Catalyst used in the production of ethylene and propylene from methanol and/or dimethyl ether, preparing the same and using the same


The application provides a catalyst for producing ethylene and propylene from methanol and/or dimethyl ether, and a preparation and application thereof. In the present application, a molecular sieve catalyst co-modified by rare earth metals and silanization is utilized.
Dalian Institute Of Chemical Physics, Chinese Academy Of Sciences
01/01/15
20150005318

1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment


This disclosure relates to a method of treating a disease selected from the group consisting of alzheimer's disease, cognitive impairment, and attention deficit hyperactivity disorder (adhd). The method includes administering a therapeutically effective amount of compound i or a pharmaceutically acceptable salt thereof to patient in need thereof, in which compound i is 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine..
H. Lundbeck A/s
01/01/15
20150005253

Novel combinations for treating acute myeloid leukaemia or chronic myeloid leukaemia


The present disclosure relates to combinations of n-[2-(2,1,3-benzothiadiazol-5-ylamino)-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-n′-(1,1-dimethylethyl)-urea and cytarabine and their use for treating aml or cml.. .
Sanofi
01/01/15
20150005207

Systems and methods for producing dimethyl sulfide from gasified coke


Petroleum coke or coal coke is gasified to produce a gas stream containing carbon monoxide, hydrogen, hydrogen sulfide, and optionally ammonia, carbon dioxide, water, and nitrogen. Carbon monoxide, hydrogen, and hydrogen sulfide, and optionally ammonia, carbon dioxide, water, and nitrogen are separated from the gas stream.
Shell Oil Company
01/01/15
20150005206

High-temperature crosslinked polymer for use in a well


A method comprising the steps of: (a) forming a fluid comprising a crosslinked polymer, wherein the crosslinked polymer comprises: (i) a first monomeric unit of one or more n-vinyl lactams; and (ii) a crosslinker selected from the group consisting of: divinyl ether, diallyl ether, vinyl or allyl ethers of polyglycols or polyols, divinylbenzene, 1,3-divinylimidazolidin-2-one, divinyltetrahydropyrimidin-2(1h)-one, dienes, allyl amines, n-vinyl-3(e)-ethylidene pyrrolidone, ethylidene bis(n-vinylpyrrolidone), and any combination of any of the foregoing; and (b) introducing the fluid into a portion of a well. The crosslinked polymer may additionally comprise: a second monomeric unit selected from the group consisting of: acrylamide, n-substituted acrylamides, methacrylamide, n-substituted methacrylamides, acrylates, methacrylates, acrylic acid, methacrylic acid, n-vinylamides, n-allyl amides, vinyl alcohol, vinyl ethers, vinyl esters, allyl alcohol, allyl ethers, allyl esters, vinylpyridine, vinyl sulfonates, allyl sulfonates, vinylimidazole, allylimidazole, diallyldimethylammonium chloride, and any combination of any of the foregoing..
Halliburton Energy Services, Inc.
01/01/15
20150004648

Reusable pcr amplification system and method


A dna amplification device utilizing a polydimethylsiloxane (pdms) and silicon substrate coated with spin-on glass (sog) is provided. This pdms layer is irreversibly bonded to the sog layer of the silicon substrate using oxygen plasma.
The Curators Of The University Of Missouri
01/01/15
20150000915

Remediation of asphaltene-induced plugging of wellbores and production lines


A method of treating a wellbore penetrating a subterranean formation comprising: providing an asphaltene solvent, wherein the asphaltene solvent comprises at least 75 mol % dimethyl sulfide and introducing the asphaltene solvent into the wellbore. .
Shell Oil Company
01/01/15
20150000907

Systems and methods for producing dimethyl sulfide from sour gas


dimethyl sulfide is produced from sour gas. The dimethyl sulfide is utilized in an oil recovery formulation introduced into a petroleum-bearing formation to enhance recovery of petroleum from the formation..
Shell Oil Company
12/25/14
20140378711

Method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde


Provided in the present invention is a method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde. The synthesis method comprises the following steps: (1) adding acetaldehyde diethyl acetal and ethyl-(1-propenyl)-ether under the effect of a catalyst to produce 1,1,3-triethoxy-2-methyl-butane; (2) pyrolysis synthesizing 1,1,3-triethoxy-2-methyl-butane under the catalytic effects of isoquinoline and p-toluenesulfonic acid to produce 1-methoxy-2-methyl-1,3-butadiene; (3) dissolving 1-methoxy-2-methyl-1,3-butadiene in anhydrous ethanol solvent for synthesis with a phase transfer catalyst, cetyl-trimethyl ammonium bromide, and a chlorinating agent, trichloroisocyanuric acid, to generate 4,4-diethoxy-3-methyl-1-chloro-butene; (4) combining 4,4-diethoxy-3-methyl-1-chloro-butene with a triphenylphosphine salt to produce a phosphonium salt; and (5) condensing the phosphonium salt under the effects of hydrogen peroxide in conjunction with sodium carbonate solution to generate 1,1,8,8-tetramethyl-2,7-dimethyl-2,4,6-octatriene; then hydrolyzing under acidic conditions to synthesize 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde.
Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
12/25/14
20140378706

Process for the preparation of (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol


The present invention relates to a process for the preparation of (1r,2r)-3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol.. .
Grunenthal Gmbh
12/25/14
20140378695

Novel process for the manufacture of methyl limonitrile


The present invention is directed to a process for the manufacture of methyl limonitrile comprising a mixture of 3,7-dimethyl-2,6-nonadiene nitrile, 3,7-dimethyl-3,6-nonadiene nitrile and 7-methyl-3-methylene-6-nonene nitrile comprising the following steps: a) reacting 6-methyl-5-octen-2-one with cyano acetic acid and removing carbon dioxide and water, wherein the reaction and the removal of carbon dioxide and water are performed in the presence of a base and a co-base 1 in an organic solvent, and wherein the organic solvent is a solvent which forms a heteroazeotrop with water; b) removing the solvent and the base of the reaction mixture obtained after having performed step a) or step c) by distillation to obtain a reaction mixture, whereby this step may optionally be performed in the presence of a co-base 2; c) isomerizing the reaction mixture obtained after having performed step a) or step b) to obtain an isomerized reaction mixture in the presence of a co-base 2; whereby step b) can be performed before or after step c).. .
Dsm Ip Assets B.v.
12/25/14
20140378644

Methods for preparation of macrocyclic polyester oligomer via heterogeneous catalysis


The invention relates to methods and systems for preparing macrocyclic polyester oligomer (mpo) directly from monomer via heterogeneous catalysis, rather than by depolymerizing a polyester. For example, in an exemplary embodiment, cyclic poly(butylene terephthalate) (cpbt) is produced by reacting butanediol (bdo) and dimethylterephthalate (dmt) in an organic solvent—for example, ortho-dichlorobenzene (odcb).
Liquid Thermo Plastics, Inc.
12/25/14
20140378542

Cocrystals of dimethyl fumarate


Disclosed herein are cocrystals of dimethyl fumarate, which is a prodrug of methyl hydrogen fumarate.. .
Xenoport, Inc.
12/25/14
20140378509

Pyrazolone derivatives as pde4 inhibitors


The compound 1-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1h-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione is a novel effective inhibitor of the type 4 phosphodiesterase useful in the treatment of psoriasis or atopic dermatitis.. .
Takeda Gmbh


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Dimethyl topics: Physiologic, Hydrochloric Acid, Fresnel Zone, Aberration, Ophthalmic, Liquid Crystal, Imaging System, Pharmaceutically Acceptable Salt, Pharmaceutically Acceptable Salts, Chloric Acid, Tartaric Acid, Fumaric Acid, Antagonist, Bradykinin, Enantiomer

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