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This page is updated frequently with new Dimethyl-related patent applications. Subscribe to the Dimethyl RSS feed to automatically get the update: related Dimethyl RSS feeds. RSS updates for this page: Dimethyl RSS RSS


Gene expression cassette and a transformant, and a method for manufacturing 2-deoxy-scyllo-inosose and a method for…

Date/App# patent app List of recent Dimethyl-related patents
09/11/14
20140259209
 Root soaking method to produce double haploid inbred lines in corn patent thumbnailRoot soaking method to produce double haploid inbred lines in corn
The subject invention pertains to a method of generating double haploid (dh) corn inbred lines from haploid corn plants. The roots of haploid corn plants are contacted with a solution/composition comprising about 0.0015m colchicine and about 0.11m dimethyl sulfoxide and the treated haploid corn plants are grown.
09/11/14
20140256960
 Gene expression cassette and a transformant, and a method for manufacturing 2-deoxy-scyllo-inosose and a method for purifying 2-deoxy-scyllo-inosose using said transformant patent thumbnailGene expression cassette and a transformant, and a method for manufacturing 2-deoxy-scyllo-inosose and a method for purifying 2-deoxy-scyllo-inosose using said transformant
A transformant is prepared to insert at least a gene expression cassette comprising a gene involved in the synthesis of 2-deoxy-scyllo-inosose into e. Coli as host cells.
09/11/14
20140256943
 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment patent thumbnail1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment
1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on sert, 5-ht3 and 5-ht1a and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.. .
09/11/14
20140256853
 Curing agent for low temperature cure applications patent thumbnailCuring agent for low temperature cure applications
The present invention provides mannich base derivatives of n,n′-dimethyl secondary diamine polymers including mannich base derivatives of methylamine-terminated poly-(n-methylazetidine) and mannich base derivatives of methylamine-terminated poly-(n-methylazacycloheptane). Amine curing agent compositions and amine-epoxy compositions containing mannich base derivatives of n,n′-dimethyl secondary diamine polymers are also disclosed..
09/11/14
20140256777
 Biocidal composition of 2,6-dimethyl-m-dioxane-4-ol acetate and methods of use patent thumbnailBiocidal composition of 2,6-dimethyl-m-dioxane-4-ol acetate and methods of use
Provided is a biocidal composition comprising 2,6-dimethyl-m-dioxane-4-ol acetate and an isothiazolinone biocidal compound. The composition is useful for controlling microorganisms in aqueous or water containing systems..
09/11/14
20140256537
 Addition of a base to enhance product yield in alkylation reactions patent thumbnailAddition of a base to enhance product yield in alkylation reactions
A process for making styrene including providing toluene, a co-feed, and a c1 source to a reactor containing a catalyst having acid sites and reacting toluene with the c1 source in the presence of the catalyst and the co-feed to form a product stream containing ethylbenzene and styrene, wherein the c1 source is selected from methanol, formaldehyde, formalin, trioxane, methylformcel, paraformaldehyde, methylal, dimethyl ether, and wherein the co-feed removes at least a portion of the acid sites on the catalyst. The co-feed can be selected from the group of aniline, amines, cresol, anisol, and combinations thereof..
09/11/14
20140256382
 Cellular telephones and touch screen displays having anti-microbial coatings patent thumbnailCellular telephones and touch screen displays having anti-microbial coatings
A touch screen and a cellular telephone are provided that may include one or more surfaces coated with an antimicrobial treatment, which may include a silane quaternary ammonium salt and isopropyl alcohol. The silane quaternary ammonium salt may initially include an unreacted organofunctional silane that subsequently reacts with and covalently bonds to the surfaces of the touch screen, such as 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride.
09/11/14
20140255505
 Pazopanib formulation patent thumbnailPazopanib formulation
A granulation formulation of 5-[[4-[(2,3-dimethyl-2h-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide or pharmaceutically acceptable salt thereof, which is adapted for reconstitution with an aqueous vehicle, and associated oral suspension.. .
09/11/14
20140255483
 Pharmaceutical composition and administrations thereof patent thumbnailPharmaceutical composition and administrations thereof
The present invention relates to pharmaceutical compositions containing a solid dispersion of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.. .
09/11/14
20140255453
 Herbal ointment for musculoskeletal and joint-related conditions patent thumbnailHerbal ointment for musculoskeletal and joint-related conditions
An herbal ointment. The herbal ointment may include about 40-45 weight percent of herb-infused oil, water or alcohol, or any desired combination thereof, about 30 weight percent purified water, about 10 weight percent emulsifier wax, about 5-10 weight percent menthol, about 3 weight percent dimethyl isosorbide, about 2 weight percent glycerin, about 2 weight percent hydrogenated methyl abietate, about 0.5 weight percent lonicera caprifolium and lonicera japanica extract, about 0.5 weight percent tocopherol, about 0.35 weight percent vanillyl butyl ether, about 0.35 weight percent xanthan gum, about 0.3 weight percent citric acid 50% aqueous solution, and about 0.25 weight percent menthyl lactate, the herb-infused oil, water or alcohol including a 1:5 dilution of herbal extracts in a solvent, wherein the herbal extracts are of german chamomile (matricaria recutita), valerian (valeriana officinalis), ginger (zingiber officinale roscoe), peppermint (mentha.times.piperita), feverfew (tanacetum parthenium), and lemon balm (melissa officinalis).
09/11/14
20140255326
Solvent formulations
The present disclosure provides, in part, a solvent composition including an an acetic acid alkyl (c1-c4) ester (e.g., methyl acetate (ma), ethyl acetate (ea), or tert-butyl acetate (tbac)) and a carbonate ester (e.g., dimethyl carbonate, or propylene carbonate). .
09/04/14
20140249291
Method of making integrated ion membrane sealing ring assembly
A method of making a sealing ring ion membrane integrated component, includes: mixing and stirring sulfonic resin with dimethylformamide; filtering the mixed liquid; placing the filtrate in a plastic container for precipitating; the sealing ring into a worktable of a drying apparatus; pouring the precipitated filtrate into the worktable of the drying apparatus, and vacuuming while drying; and taking the dried integrated ion membrane sealing ring assembly out of the drying apparatus, and then cooling the assembly.. .
09/04/14
20140249117
Active ingredient combination of a retinoid and a hormone combination with contraceptive action as medicament for treatment of skin diseases
The present invention relates to a medicament, the active ingredient combination of which consists of a retinoid selected from the group consisting of acitretin [9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid], etretinate [ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate], isotretinoin [3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid] and tretinoin [3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid] and of a hormone combination with contraceptive action of an oestrogen component and a gestagen component, and to a dosage form consisting of at least 28 daily units, of which the final 7-3 daily units contain only the retinoid as active ingredient and the other daily units also contain the hormone-containing active ingredient combination, and to the use thereof for treating acne, seborrhoea or psoriasis.. .
09/04/14
20140248772
Method for tuning a deposition rate during an atomic layer deposition process
Embodiments of the invention provide methods for depositing a material on a substrate within a processing chamber during a vapor deposition process, such as an atomic layer deposition (ald) process. In one embodiment, a method is provided which includes sequentially exposing the substrate to a first precursor gas and at least a second precursor gas while depositing a material on the substrate during the ald process, and continuously or periodically exposing the substrate to a treatment gas prior to and/or during the ald process.
09/04/14
20140248356
1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment
1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on sert, 5-ht3 and 5-ht1a and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.. .
09/04/14
20140248355
1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment
1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on sert, 5-ht3 and 5-ht1a and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.. .
08/28/14
20140243564
Method for inhibiting fouling in basic washing systems
Fouling in basic washing systems such as caustic scrubbers can be prevented or at least mitigated by treating the liquid washing phase used in a caustic scrubber with an additive having at least one compound selected from the group consisting of oxalyl dihydrazide, a disulfite salt, isopropyl hydroxylamine, chlorobenzhydrazide, aminobenzhydrazide, a thiosulfate salt, 4,4-dimethyl oxazolidine, a hydrosulfite salt, and mixtures thereof, particularly in the case where the liquid washing phase includes components that may undergo an aldol condensation, the products of which may cause fouling solids and/or sludges.. .
08/28/14
20140243361
Polymorphs of arry-380, a selective herb2 inhibitor and pharmaceutical compositions contianing them
Polymorphs of n4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-n6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine are provided herein. Processes for preparing the polymorphs and pharmaceutical composition comprising the polymorphs are also disclosed..
08/28/14
20140242723
Methods for detecting symmetrical dimethylarginine
Method of detecting symmetrical dimethyl arginine (sdma) in biological samples. Sdma analogs for generating anti-sdma antibodies having little or no cross-reactivity with asymmetrical dimethyl arginine, arginine, and monomethylarginine.
08/28/14
20140242713
Nanoporous detectors of monocyclic aromatic compounds and other pollutants
Porous sol-gel material essentially consisting of units of one or more first polyalkoxysilanes chosen from the following compounds: (chloromethyl)triethoxysilane; 1,3-dimethyltetramethoxydisiloxane; ethyltrimethoxysilane; triethoxy(ethyl)silane; triethoxymethylsilane; triethoxy(vinyl)silane; trimethoxymethylsilane; trimethoxy(vinyl)silane; tetraethoxysilane or tetramethoxysilane (tmos) and of units of one or more second polyalkoxysilanes chosen from the following compounds: (n-(3-(trimethoxysilyl)propyl)ethylenediamine; 3-aminopropyltriethoxysilane (aptes) and 3-aminopropyltrimethoxysilane, in a first polyalkoxysilane/second polyalkoxysilane molar ratio of 1/0.01 to 1/1, optionally comprising a probe molecule, method of preparation and applications in the trapping of monocyclic aromatic hydrocarbons and other pollutants or in their detection.. .
08/28/14
20140242516
Silane composition and cured film thereof, and method for forming negative resist pattern using same
A polyether-modified polydimethylsiloxane.. .
08/28/14
20140242172
Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
The present invention relates to solid state forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (compound 1), pharmaceutical compositions thereof and methods therewith.. .
08/28/14
20140238477
Anti-reflective coating for photovoltaic cells
A surface of a photovoltaic cell is coated with a solution that includes barium titanate to reduce reflection of sunlight that is incident on the surface. The solution may include a base of polydimethylsiloxane and carbon nanotubes.
08/21/14
20140235875
Method for producing cyclic carbonates
Linear or cyclic carbonates as potential monomers for isocyanate-free polyurethanes and polycarbonates were prepared from polyols and dialkyl carbonates or diphenyl carbonates. This invention was developed to produce linear or cyclic carbonates with or without using catalysts.
08/21/14
20140235728
Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods of preparing the same and use of the same
The present disclosure relates to polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same.. .
08/21/14
20140235682
Aqueous agrochemical suspension composition and aqueous agrochemical suspension formulation
The present invention provides an agrochemical composition having excellent efficacy, which comprises, as active ingredient, 2-(2,6-difluorophenyl)-4-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydrooxazole. The aqueous agrochemical suspension composition comprising 2-(2,6-difluorophenyl)-4-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydrooxazole, at least one kind of alcohol selected from the group consisting of ethylene glycol, propylene glycol and glycerin, an inorganic thickener and a dispersant shows excellent efficacy..
08/21/14
20140235639
Novel compounds
Wherein r1 is 2-indanyl, r2 is 1-methylpropyl, r3 is a group selected from 2,6-dimethyl-3-pyridyl or 4,6-dimethyl-3-pyridyl, r4 represents methyl and r5 represents hydrogen or methyl or, r4 and r5 together with the nitrogen atom to which they are attached represent morpholino and pharmaceutically acceptable derivatives thereof are described, as are processes for their preparation, pharmaceutical compositions containing them and their use in medicine, particularly their use as oxytocin antagonists.. .
08/21/14
20140235519
4,8-dimethyl-4,9-decadienenitrile
It is intended to provide a compound and a fragrance composition containing the compound, wherein the compound is useful as a fragrance, has floral and green odors in addition to a strong muguet odor, is stable in an aqueous vehicle, and can be blended with another fragrance to have enhanced freshness and diffusibility. It also is intended to provide 4,8-dimethyl-4,9-decadienenitrile and a fragrance composition containing 4,8-dimethyl-4,9-decadienenitrile..
08/21/14
20140234642
Resin compositions for thermosetting powder coating compositions
The invention relates to a resin composition comprising at least an organophosphorous compound and a branched amorphous carboxylic acid functional polyester, said polyester having a tg of at least 40° c., said polyester comprising at least 1 to 45% mol of 2,2-dimethyl-1,3-propanediol; a c3 to c5 aliphatic diol ad1 not including 2,2-dimethyl-1,3-propanediol; a c6 to c50 aliphatic or cycloaliphatic diol ad2; 0.1 to 10% mol of an at least trifunctional monomer; 1 to 55% mol of terephthalic acid, wherein the % mol is based on the polyester. The powder coatings of the present invention derived upon curing at low temperature of the thermosetting powder coating compositions of the invention that were storage stable and comprised said resin composition and a crosslinker having functional groups that are reactive with the carboxylic acid groups of the polyester, have limited or no blooming, good smoothness sufficient reverse impact resistance and preferably have also good degassing limit..
08/21/14
20140234244
Floral perfuming compositions as substitutes for lilial®
A floral fragrance composition for use as a replacement for 3-(4-tertbutylphenyl)-2-methylpropanal (lilial®) that is a primary perfuming ingredient composition that includes a first perfuming ingredient of (2,5-dimethyl-2,3-dihydro-ih-inden-2-yl) methanol (lilyflore®) in an amount of 5 to 25% by weight; a second perfuming ingredient of a dimethyl-5-indanyl propanal compound in an amount of 0.2 to 10% by weight; and one or more secondary perfuming ingredients including at least one of 3-methyl-5-phenylpentanal, decanal, octanal, cuminic aldehyde, cuminic alcohol, carvone, tetrahydro-2-isobutyl-4-methyl-4(2h)-pyranol, or cis-7-p-menthanol.. .
08/21/14
20140234240
Less yellowing nail coating
A composition for forming a less yellowing coating on a nail. The composition includes a curable resin, a monomer, a photoinitiator and a photosynergist comprising a methacrylate primary amine monomer.
08/14/14
20140228609
Method and system for producing olefins from dimethyl ether
To render the temperature profile over the catalyst stages as flat as possible, but close to the optimum operating temperature, gaseous dimethyl ether in a purity of 70-100 wt-% together with recycle gas, which contains olefinic, paraffinic and aromatic hydrocarbons, is charged to at least one downstream catalyst stage, wherein this downstream catalyst stage additionally is fed with product gas from the upstream catalyst stage.. .
08/14/14
20140228582
Process for preparation of zolmitriptan
The present invention provides a convenient and industrially viable process for preparation of zolmitriptan (i) having desired purity. The invention specifically relates to a method for isolating (s)-4-(4-hydrazinobenzyl)-1,3-oxazolidin-2-one hydrochloride (iiia) of desired purity by separating the undesired inorganic side products such as stannous hydroxide by manipulation of ph at different stages and finally treating with n,n-dimethylamino butyraldehyde diethyl acetal in an acidic medium to provide zolmitriptan (i) conforming to regulatory specifications..
08/14/14
20140228562
Treatment of sleep disorders
The use of 7-chloro-3-(5-dimethylaminomethyl-[1,2,4]oxadiazol-3-yl)-5methyl-4,5-dihydro-imidazol[1,5,-a][1,4]benzodiazepine-6-one or its pharmaceutically acceptable salt for treating various types of insomnia.. .
08/14/14
20140228522
Dissoluble pdms-modified p(hema-maa) amphiphilic copolymer and method for fabricating the same
The present invention discloses a dissoluble pdms-modified p(hema-maa) amphiphilic copolymer and the method of fabricating the same. The amphiphilic copolymer of the present invention is fabricated via chemically bonding hema, maa, and poly(dimethylsiloxane), bis(3-aminopropyl) terminated (pdms) in aqueous solution.
08/14/14
20140228483
Compositions useful for preparing composites and composites produced therewith
A thermosettable epoxy resin composition having, as components: (1) an epoxy resin; (2) an epoxidized cycloaliphatic dicyclopentadiene phenolic resin; (3) a liquid oligomeric butadiene homopolymer; and (4) a curing agent including one or more alkylphenol novolac resins or alkyphenol co-novolac resins, and one or more poly(2,6-dimethyl-1,4-phenylene oxides), which resin composition may be used to prepare composites, prepregs, or laminates.. .
08/14/14
20140228385
Process for rilpivirine
The present invention provides a novel process for the preparation of 4-(4-hydroxypyrimidin-2-ylamino)benzonitrile. The present invention also provides a novel process for the preparation of 4-iodo-2,6-dimethyl benzenamine.
08/14/14
20140224150
Active energy ray-curable inkjet magenta ink composition
The present invention provides an active energy ray-curable inkjet magenta ink composition that achieves excellent color reproducibility and is also excellent in storage stability, and an ink set using the composition. The magenta ink composition according to the present invention contains, as two kinds of quinacridone pigments, (a) unsubstituted quinacridone and (b) 2,9-dimethylquinacridone..
08/14/14
20140223807
Fuel for compression-ignition engines based on monooxymethylene dimethylether
A fuel for compression-ignition engines is described, which contains mono oxymethylene dimethyl ether and has a cetane number of ≧51. This fuel for compression-ignition engines advantageously contains oxygenates of the n-polyoxaalkane type and/or di-tert-butyl peroxide.
08/07/14
20140221626
Compositions and methods for detection of methadone metabolite
Methods and reagents are disclosed for conducting assays for eddp. The reagents include a moiety selected from the group consisting of poly(amino acid) label moieties, non-poly(amino acid) label moieties, poly(amino acid) immunogenic carriers, non-poly(amino acid) immunogenic carriers, non-label poly(amino acid) moieties, and non-immunogenic carrier poly(amino acid) moieties linked to 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine at the 3-position of one of the phenyl rings.
08/07/14
20140221477
Process for the preparation of a sulfated derivative of 3,5-diiodo-o-[3-iodophenyl]-l-tyrosine
The present invention relates to a process for the preparation of the mono sodium salt of the derivative 3,5-diiodo-o-[3-iodo-4-(sulphooxy)phenyl]-l-tyrosine (t3s) by starting from the corresponding phenolic compound, in the presence of chlorosulfonic acid and dimethylacetamide as a solvent. The so obtained t3s compound may conveniently be isolated in a pure form as a solid in good yields.
08/07/14
20140221474
Method and formulation for chemical peeling
A chemical peeling formulation and a formulation able to increase the efficacy and the tolerability of preparations based on the use of compounds used to carry out chemical peeling, comprising at least one keratolytic agent and dimethyl isosorbide. The composition may additionally comprise dimethyl sulphone..
08/07/14
20140221444
Novel crystals and process of making 5-(-methyl)-2-methoxy-benzoic acid
The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid.. .
08/07/14
20140221424
Pharmaceutical compositions for use in the treatment of cystic fibrosis
The present invention relates to the use of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide and pharmaceutical compositions thereof for the treatment of cystic fibrosis, in patients, including kits and/or products thereof.. .
08/07/14
20140221369
5-deutero-2,4-thiazolidinedione and 5-deutero-2,4-oxazolidinedione derivatives and compositions comprising and methods of using the same
The invention provides 5-deuterium enriched 2,4-thiazolidinediones and 2,4-oxazolidinediones, such as 5-(4-((6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1h-benzo[d]imidazol-2-yl)methoxy)benzyl)-5-deutero-thiazolidine-2,4-dione, deuterated derivatives thereof, stereoisomers thereof, pharmaceutically acceptable salt forms thereof, and methods of treating medical disorders, such as cancer, using the same.. .
08/07/14
20140220698
Method for rapidly measuring melatonin adulteration of chinese patent medicine or healthcare food
A method for rapidly measuring melatonin adulteration of chinese patent medicines and healthcare foods comprises: (1) extracting melatonin added to a chinese patent medicine or healthcare food by using ethyl acetate; and (2) adding p-dimethylaminocinnamaldehyde to the extracted solution, and observing color. The method is rapid, simple and convenient, has strong specificity, high accuracy, reaction sensitivity, and a wide application range, and is applicable to on-site detection of melatonin adulteration of a chinese patent medicine or healthcare food..
08/07/14
20140220141
Compositions of lopinavir and ritonavir
The present inventions relates to a solid composition and an aqueous dispersion comprising nanoparticles of the anti-retroviral drugs lopinavir and ritonavir. The solid composition and aqueous dispersion additionally comprise a mixture of a hydrophilic polymer and a surfactant.
08/07/14
20140220140
Compositions of efavirenz
The present inventions relates to a solid composition and an aqueous dispersion comprising nanoparticles of the anti-retroviral drug efavirenz. The solid composition and aqueous dispersion additionally comprise a mixture of a hydrophilic polymer and a surfactant.
08/07/14
20140219942
Sunscreens
The present invention relates to a composition for topical application comprising at least a benzotriazol derivative and a cosmetic solvent selected from the group consisting of benzoate solvents such as phenethyl benzoate, dimethyl capramide and diethylhexyl 2,6-naphthalate. Furthermore, the invention relates to the use of specific benzotriazol derivatives to mask the off-odor of cosmetic solvents such as particularly phenethyl benzoate, dimethyl capramide and diethylhexyl 2,6-naphthalate..
08/07/14
20140219932
Enamel protectant and repair toothpaste
Substantially aqueous-free, enamel protectant and enamel repair toothpastes containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein: (a) substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and (b) said toothpastes indicate substantially improved, enamel protectant factor (epf) and enamel repair factor (erf) values compared to fluoride brushing treatments with comparable or higher fluoride levels.. .
08/07/14
20140216405
Fuel injection nozzle
A fuel injection nozzle includes: a nozzle body having a plurality of injection holes; and a needle accommodated in the nozzle body to inject a dme fuel containing dimethyl ether as a main component. The nozzle body has a seat part to which the needle seated or from which the needle separated, and a tip end chamber arranged downstream of the seat part in a flow of the dme fuel to communicate with the plurality of injection holes.
07/31/14
20140213814
Process for extraction of peptides and its application in liquid phase peptide synthesis
A process for extraction of a peptide from a reaction mixture resulting from a peptide coupling reaction, the reaction mixture containing the peptide and a polar aprotic solvent selected from n,n-dimethylformamide, n,n-dimethylacetamide and n-methyl-2-pyrrolidone, whereby the process includes a step a) and a step b): step a) including the addition of a component a1) and a component a2), whereby component a1) is toluene and component a2) is water, to the reaction mixture, so that a biphasic system with an organic layer and an aqueous layer is obtained; step b) including the subsequent separation of the organic layer containing the peptide from the aqueous layer. In an embodiment, a combination of toluene and an organic solvent 1 selected from n-heptane, 2-methyltetrahydrofuran, ethylacetate, isopropylacetate, acetonitrile and tetrahydrofuran is used for the process for extraction.
07/31/14
20140213759
Process for extraction of peptides and its application in liquid phase peptide synthesis
A process for extraction of a peptide from a reaction mixture resulting from a peptide coupling reaction, the reaction mixture containing the peptide and a polar aprotic solvent selected from the group consisting of n,n-dimethylformamide, n,n-dimethylacetamide and n-methyl-2-pyrrolidone, whereby the process includes a step a) and a step b): step a) including the addition of a component a1) and a component a2), whereby component a1) is 2-methyltetrahydrofuran and component a2) is water, to the reaction mixture, so that a biphasic system with an organic layer and an aqueous layer is obtained; step b) including the subsequent separation of the organic layer containing the peptide from the aqueous layer. In an embodiment, a combination of 2-methyltetrahydrofuran and an organic solvent 1 selected from the group consisting of n-heptane, toluene, ethylacetate, isopropylacetate, acetonitrile and tetrahydrofuran is used for the process for extraction.
07/31/14
20140213596
Salts and crystalline forms of an apoptosis-inducing agent
Salts and crystalline forms of 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-n-({3-nitro-4-[(tetrahydro-2h-pyran-4-ylmethyl)amino]phenyl}-sulfonyl)-2-(1h-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide are suitable active pharmaceutical ingredients for pharmaceutical compositions useful in treatment of a disease characterized by overexpression of one or more anti-apoptotic bcl-2 family proteins, for example cancer.. .
07/31/14
20140213495
Perfuming acetal
The present invention concerns the use as perfuming ingredient of 4-dimethoxymethyl-1,3-dimethyl-1-cyclohexene in the form of any one of its stereoisomers or a mixture thereof, for instance to impart odor notes of the grapefruit and floral type.. .
07/31/14
20140213494
Use of 4,8 dimethyl-3,7 nonadien-2-ol as fragrance
4,8-dimethyl-3,7-nonadien-2-ol in which the weight ratio of (e)-4,8-dimethyl-3,7-nonadien-2-ol to the sum of (e)- and (z)-4,8-dimethyl-3,7-nonadien-2-ol is at least 80% or in which the weight ratio of (z)-4,8-dimethyl-3,7-nonadien-2-ol to the sum of (e)- and (z)-4,8-dimethyl-3,7-nonadien-2-ol is at least 80%, is used as fragrance. The fragrances have a unique rose-like, floral character.
07/31/14
20140213136
Fast response nanofiber articles with tunable wettability and bulk properties
A fibrous properties-switching article comprises a mat consisting of fibers having a fiber diameter of 2 microns or less. The fibers comprise a polymer, copolymer, polymer blend, or polymer network, wherein the fibers have a diameter of 2 gm or less.
07/31/14
20140212942
Production of volatile dienes by enzymatic dehydration of light alkenols
Described is a method for generating conjugated dienes through a biological process. More specifically, the application describes a method for producing conjugated dienes (for example butadiene, isoprene or dimethylbutadiene) from light alkenols via enzymatic dehydration, in particular by making use of an alkenol dehydratase..
07/31/14
20140212552
Cookware release compositions
A cookware release composition having edible oil and a silicone polymer. The cookware release composition can contain an edible oil and greater than 1000 ppm polydimethylsiloxane.
07/31/14
20140212501
Compositions of lopinavir
The present invention relates to a solid composition and an aqueous dispersion comprising nanoparticles of the anti-retroviral drug lopinavir. The solid composition and aqueous dispersion additionally comprise a mixture of a hydrophilic polymer and a surfactant.
07/31/14
20140212493
Highly bioavailable composition containing eprosartan - poloxamer complex or 2-(7-chloro-5-methyl-4-oxo-3-phenyl-4,5-dihydro-3h-pyridazine (4,5-b)indol-1-yl)-n,n-dimethylacetamide - poloxamer complex
A composition including an association complex of a pharmaceutical composition and one or more polyethylene-polypropylene glycol block copolymers (poloxamers) is provided. The pharmaceutical composition may include a member selected from the group consisting of (a) an association complex of an eprosartan composition including eprosartan or a pharmaceutically acceptable salt of eprosartan and (b) the non-zwitterionic compound 2-(7-chloro-s-methyl-4-oxo-3-phenyl-4,s dihydro-3h-pyridazino (4,s-b)indol-1-yl)n, n-dimethylacetamide (nz)..
07/31/14
20140212388
Composition for cosmetic and health improvement
The invention relates to compositions in a form of health drinks, capsules, tablets or powders. In particular the compositions improve individual's general health, maintain and improve regeneration of human connective tissue and simultaneously provide positive cosmetic effects for a better life and more happiness for all, male, female, young and old.
07/31/14
20140209026
Plasma activated deposition of a conformal film on a substrate surface
An apparatus deposits a film on a substrate including a reaction chamber arranged on a substrate support. An inlet port delivers gas phase reactants to the reaction chamber.
07/24/14
20140207221
Capacitor electrolyte
A capacitor for an implantable medical device is presented. The capacitor includes an anode, a cathode, a separator therebetween, and an electrolyte over the anode, cathode, and separator.
07/24/14
20140206888
Methods for preparation of thiophene compounds
Or a pharmaceutically acceptable salt thereof includes: a) reacting compound (a) with 3,3-dimethylbut-1-yne in the presence of one or more palladium catalysts selected from the group consisting of pd(pph3)4 and pd(pph3)2cl2, and one or more copper catalysts selected from the group consisting of cui, cubr, and cucl, to generate compound (b); b) treating compound (b) with an acid to generate compound (c): c) reducing the cyclohexanone of compound (c) to cyclohexanol to generate compound (d); and d) reacting compound (d) with a base to generate compound (1), wherein compounds (a), (b), (c), and (d) are each as depicted herein.. .
07/24/14
20140206874
Crystal form i of salt of a dipeptidyl peptidase-iv inhibitor and preparation method and use same
The present invention relates to the crystal form i of salt of a dipeptidyl peptidase-iv inhibitor, and the preparation method and use thereof. In particular, it relates to the crystal form i of dihydrochloride salt of the compound (r)-2-[[7-(3-aminopiperidin-1-yl)-3,5-dimethyl-2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile represented by formula (1), which is a dipeptidyl peptidase-iv inhibitor, and the preparation method and use thereof.
07/24/14
20140206867
Process for preparing cyclopentylamine derivatives and intermediates thereof
Disclosed herein is an improved process for the preparation of substituted cyclopentanamine derivatives, which are useful intermediates in the preparation of triazolo[4,5-d]pyrimidine compounds. Particularly described is an improved, commercially viable and industrially advantageous process for the preparation of a ticagrelor intermediate, [3ar-(3aα,4α,6α,6aα]-2-[[6-amino-2,2-dimethyltetrahydro-4h-cyclopenta-1,3-dioxol-4-yl]oxy]-ethanol, alternatively named, 2-[[(3ar,4s,6r,6as)-6-amino-2,2-dimethyltetrahydro-3ah-cyclopenta[d][1,3]-dioxol-4-yl]oxy]-1-ethanol..
07/24/14
20140206741
N-substituted isopropyldimethyl azulene sulfonamide derivatives, and preparation method and use thereof
The present invention provides an n-substituted isopropyldimethyl azulene sulfonamide derivative as represented by formula (i), and preparation method and uses thereof, wherein r1 is an alkyl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, amino, or a substituted alkyl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, and amino. The n-substituted isopropyldimethyl azulene sulfonamide derivative can be used in treating gastric ulcer..


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Dimethyl topics: Physiologic, Hydrochloric Acid, Fresnel Zone, Aberration, Ophthalmic, Liquid Crystal, Imaging System, Pharmaceutically Acceptable Salt, Pharmaceutically Acceptable Salts, Chloric Acid, Tartaric Acid, Fumaric Acid, Antagonist, Bradykinin, Enantiomer

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