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Differentiation patents



      
           
This page is updated frequently with new Differentiation-related patent applications. Subscribe to the Differentiation RSS feed to automatically get the update: related Differentiation RSS feeds. RSS updates for this page: Differentiation RSS RSS


Date/App# patent app List of recent Differentiation-related patents
07/17/14
20140201774
 Systems and methods for multi-broadcast differentiation patent thumbnailSystems and methods for multi-broadcast differentiation
A system and method is disclosed for resolving false positives in a centralized, real-time automatic content recognition system that is ingesting, fingerprinting, and attempting to match for recognition purposes, multiple streams of broadcast content that are simultaneously arriving from a plurality of sources. In particular, the problem of identifying which specific broadcast of certain programming has been matched, including the episode of a series, as well as the channel, time zone and time of broadcast and whether the programing is being watched “live” as broadcast or from a dvr time-shifted source, is addressed.
07/17/14
20140200466
 Polymeric materials patent thumbnailPolymeric materials
Topographical features, such as projections or recesses, having a maximum dimension which is less than 3 μm, with the features being separated by a distance which is less than 10 μm are transferred to polyetheretherketone, on an industrial scale, by injection moulding relatively low viscosity peek, using a mould in which is arranged a master structure which carries the desired topography. The topographical features increase the water contact angle of a surface which includes them and such a modified surface has been shown to influence cell attachment and differentiation.
07/17/14
20140200201
 Enzymatic production or chemical synthesis and uses for 5,7-dienes and uvb conversion products thereof patent thumbnailEnzymatic production or chemical synthesis and uses for 5,7-dienes and uvb conversion products thereof
Provided herein are steroidal compounds that are androsta-5,7-dienes or a pregna-5,7-dienes and ultraviolet b (uvb) conversion products thereof which includes pharmaceutical compositions of the steroidal compounds as shown in tables 1 and 2. Also provided is a method for producing hydroxylated metabolites of cholecalciferol or ergocalciferol via the p450scc (cyp11a1) or cyp27b1 enzyme systems where the hydroxylase has an activity to hydroxylate position c20 of a secosteroid or its 5,7-dieneal precursor and the hydroxylated metabolites so produced.
07/17/14
20140200174
 Peptide bfp4 for promoting osteogenesis or vascularization and use thereof patent thumbnailPeptide bfp4 for promoting osteogenesis or vascularization and use thereof
Disclosed are a peptide for promoting osteogenesis and vascularization, and the use thereof. The peptide has a low molecular weight so that it can be economically produced.
07/17/14
20140199761
 Promoter-regulated differentiation-dependent self-deleting cassette patent thumbnailPromoter-regulated differentiation-dependent self-deleting cassette
Targeting constructs and methods of using them are provided for differentiation-dependent modification of nucleic acid sequences in cells and in non-human animals. Targeting constructs comprising a promoter operably linked to a recombinase are provided, wherein the promoter drives transcription of the recombinase in an differentiated cell but not an undifferentiated cell.
07/17/14
20140199700
 Method for producing intestinal cells patent thumbnailMethod for producing intestinal cells
An object of the present invention is to provide a method of producing intestinal cells by use of pluripotent stem cells as a starting material. According to the present invention, provided is a method of producing intestinal cells, comprising the steps of: (a) inducing differentiation of pluripotent stem cells into definitive endoderm cells; and (b) culturing the definitive endoderm cells in the presence of (2′z,3′e)-6-bromoindirubin-3′-oxime (bio) and n-[(3,5-difluorophenyl)acetyl]-l-ala-2-phenyl-l-gly-tert-butyl-oh (dapt) to thereby induce differentiation of the definitive endoderm cells into intestinal cells..
07/17/14
20140199327
 Methods of promoting differentiation patent thumbnailMethods of promoting differentiation
Provided herein are methods of promoting cell fate change, particularly differentiation of tumor cells, by inhibition of usp1, uaf1, and/or id (e.g., id1, id2, and/or id3).. .
07/17/14
20140199315
 Sp35 antibodies and uses thereof patent thumbnailSp35 antibodies and uses thereof
Endogenous sp35 is a negative regulator for neuronal survival, axon regeneration, oligodendrocyte differentiation and myelination (negative regulator). Molecules that block endogenous sp35 function, such anti-sp35 antibodies can be used as therapeutics for the treatment of neuron and oligodendrocyte dysfunction.
07/17/14
20140199278
 Brown adipocyte modification patent thumbnailBrown adipocyte modification
Methods and therapeutics are provided for treating metabolic disorders by increasing activation of brown adipose tissue. Generally, the methods and therapeutics can increase activation of brown adipose tissue to increase energy expenditure and induce weight loss.
07/17/14
20140197078
 Separation apparatus and separation method patent thumbnailSeparation apparatus and separation method
A separation apparatus according to the present invention includes: a conveyor that conveys a group of pieces; a material distinguishing unit that distinguishes between first pieces and second pieces that are placed on the conveyor, according to material; a blower that generates airflow supplied from a middle of the conveyor toward a conveying end along a conveying surface; a first separation unit that blows off the first pieces thrown forward from the conveying end, based on a differentiation result obtained by the material distinguishing unit; a second separation unit that blows off the second pieces toward a different place; and a current plate provided below the group of pieces thrown forward and protruding from the conveyor.. .
07/10/14
20140193909
Direct differentiation of cardiomyocytes from embryonic stem cells
The present invention relates to the induction of differentiation in human embryonic stem (hes) cells to cardiomyocytes and factors such as prostaglandin i2 (pgi2), fgf 9, bmp6, bmp4, scf, igf2, and insulin that influence the process of differentiation to cardiomyocytes. Media that is appropriate for the induction of differentiation of cardiomyocytes from hes cells is also provided wherein the media contains these factors.
07/10/14
20140193904
Pdx1 expressing endoderm
Disclosed herein are cell cultures comprising pdx1-positive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified pdx1-positive endoderm cells as well as methods for enriching, isolating and purifying pdx1-positive endoderm cells from other cell types.
07/10/14
20140193902
Pdx1 expressing endoderm
Disclosed herein are cell cultures comprising pdx1-positive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified pdx1-positive endoderm cells as well as methods for enriching, isolating and purifying pdx1-positive endoderm cells from other cell types.
07/10/14
20140193895
Automated tissue engineering system
The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources.
07/10/14
20140193811
Culture based screening assay and methods of use thereof to identify agents which modulate tumor development, invasion and differentiation
A 3d organotypic culture which phenocopies aggressive, invasive cancer and methods of use thereof are provided.. .
07/10/14
20140193380
Technologies, methods, and products of small molecule directed tissue and organ regeneration from human pluripotent stem cells
Pluripotent human embryonic stem cells (hescs) hold great potential for restoring tissue and organ function, which has been hindered by inefficiency and instability of generating desired cell types through multi-lineage differentiation. This instant invention is based on the discovery that pluripotent hescs maintained under defined culture conditions can be uniformly converted into a specific lineage by small molecule induction.
07/10/14
20140193374
Methods and compositions for culturing cells
The invention provides, among other things, methods and compositions for expanding stem cells. The invention further provides methods, devices and systems for directing differentiation of expanded stem cells.
07/10/14
20140193356
Compositions comprising citrate and applications thereof
In one aspect, methods of promoting bone growth are described herein. In some embodiments, a method of promoting bone growth described herein comprises promoting cell differentiation or phenotype progression in a population of bone cells by providing a citrate-presenting composition to the population of bone cells.
07/10/14
20140192934
Receiver filter for dc-wander removal in a contactless smartcard
Embodiments of a method for processing a baseband signal in a direct current (dc)-suppressed system, a system for processing a baseband signal in a dc-suppressed system, and a smart card are described. In one embodiment, a method for processing a baseband signal in a dc-suppressed system involves processing the baseband signal in the analog domain with a first high pass filter (hpf), converting the processed baseband signal to a digital signal, and processing the digital signal in the digital domain with a second hpf to provide a discrete-time differentiation of the baseband signal.
07/03/14
20140189900
Mirna-regulated differentiation-dependent self-deleting cassette
Targeting constructs and methods of using them are provided for differentiation-dependent modification of nucleic acid sequences in cells and in non-human animals. Targeting constructs comprising a promoter operably linked to a recombinase are provided, wherein the promoter drives transcription of the recombinase in an differentiated cell but not an undifferentiated cell.
07/03/14
20140189652
Filtering and transforming a graph representing an application
A graph representing code element and relationships between code elements may have elements combined to consolidate or collapse portions of the graph. A filter may operate between the graph data and a renderer to show the graph in different states.
07/03/14
20140187743
Surface-active collagen membrane by peptide
The present invention provides a collagen membrane having surface activity by a fusion peptide bound to the surface thereof. When the collagen membrane is transplanted in vivo, the retention time of the fusion peptide in a local region can increase, and the fusion peptide can promote the cell migration, proliferation and differentiation associated with bone tissue regeneration, thereby maximizing the ability to regenerate bone tissue.
07/03/14
20140187632
Lipid compositions for the treatment of gastro-intestinal disorders and the promotion of intestinal development and maturation
The present invention provides a use of a lipid composition for the preparation of a nutritional, pharmaceutical or nutraceutical composition or a functional food, for the prevention and treatment of gastrointestinal diseases and disorders, and for promoting intestinal development, maturation, adaptation and differentiation.. .
07/03/14
20140187622
Composition comprising coumestrol or a bean extract containing coumestrol
The present invention relates to a composition which comprises as an active ingredient coumestrol or a bean extract containing coumestrol, whereby adipocyte differentiation is inhibited, the immune system of the body is improved, toxic substances are purged, and neurodegenerative disorders are prevented or improved.. .
07/03/14
20140187621
Composition comprising coumestrol or a bean extract containing coumestrol
The present invention relates to a composition which comprises as an active ingredient coumestrol or a bean extract containing coumestrol, whereby adipocyte differentiation is inhibited, the immune system of the body is improved, toxic substances are purged, and neurodegenerative disorders are prevented or improved.. .
07/03/14
20140187620
Composition comprising coumestrol or a bean extract containing coumestrol
The present invention relates to a composition which comprises as an active ingredient coumestrol or a bean extract containing coumestrol, whereby adipocyte differentiation is inhibited, the immune system of the body is improved, toxic substances are purged, and neurodegenerative disorders are prevented or improved.. .
07/03/14
20140187618
Compositions, methods and kits using for inducing or enhancing neurogenesis in cells and tissue
Compositions, methods, and kits including extracts containing physalins and pure physalins are provided for inducing neurogenesis in cells and tissues. The extracts for example are obtained from natural sources such as a plant, for example physalis angulata.
07/03/14
20140186954
Optimized methods for differentiation of cells into cells with hepatocyte and hepatocyte progenitor phenotypes, cells produced by the methods, and methods for using the cells
The invention is directed to methods for culturing cells so that the cells are induced to differentiate into cells that express hepatocyte phenotypes and hepatocyte progenitor phenotypes. More particularly, the invention relates to methods for culturing cells so that the cells are induced to differentiate into cells that express a definitive endodermal phenotype, a liver-committed endodermal phenotype, a hepatoblast phenotype, and hepatocyte phenotype.
07/03/14
20140186953
Differentiation of human embryonic stem cells into pancreatic endocrine cells using hb9 regulators
The present invention provides methods to promote differentiation of pluripotent stem cells to pancreatic endoderm cells expressing pdx1, nkx6.1, and hb9. In particular, the methods encompass culturing stage 4 to stage 6 cells with a thyroid hormone (e.g.
07/03/14
20140186937
Automated tissue engineering system
The invention provides systems, modules, bioreactor and methods for the automated culture, proliferation, differentiation, production and maintenance of tissue engineered products. In one aspect is an automated tissue engineering system comprising a housing, at least one bioreactor supported by the housing, the bioreactor facilitating physiological cellular functions and/or the generation of one or more tissue constructs from cell and/or tissue sources.
07/03/14
20140186308
Compositions for directing adipose-derived stem cells to a chondrogenic differentiation and methods of use therefor
Composition and methods are provided to stimulate the proliferation and differentiation of pluripotent stem cells into chondrocytes. The method comprises the steps of contacting the pluripotent stem cells with an ab2 chimeric polypeptide under conditions suitable for grown and proliferation of the cells..
07/03/14
20140186305
Culturing of human embryonic stem cells at the air-liquid interface for differentiation into pancreatic endocrine cells
The present invention provides methods, cell cultures and differentiation media to promote differentiation of pluripotent stem cells to pancreatic endocrine cells expressing pdx1, nkx6.1, and hb9 by culturing in a culture vessel at the air-liquid interface. The invention also provides for in vivo maturation of cells cultured at the air-liquid interface..
07/03/14
20140185442
Supporting quality of service differentiation using a single shared buffer
An example method, system, and switching element are provided and may provide for an egress port to be configured to receive a plurality of data packets, each of the plurality of data packets being a class of a plurality of classes. A buffer may communicate with the at least one data port interface.
07/03/14
20140183280
Flow device
A flow device automatically impels a fluid to disperse from a container without requiring significant physical exertion, such as a repetitive pumping motion, to propel the fluid through. The flow device automatically causes an intake fluid to flow from an intake end of a container, and pass through an interior channel of the container.
06/26/14
20140179614
Metallothionein-derived peptide fragments
The present invention relates to neural cell survival, differentiation and proliferation promoting peptide fragments derived from metallothioneins (mt), pharmaceutical compositions comprising said peptide fragments and uses thereof for treatment of diseases and conditions where the effects of stimulating neural cell proliferation, differentiation and/or survival, and/or stimulating neural plasticity associated with learning and memory are beneficial for treatment.. .
06/26/14
20140179604
Ghrh agonists for the treatment of ischemic disorders
Disclosed herein are compositions of ghrh agonists and peptides, and methods to treat disorders, such as ischemia and reperfusion injury. In one embodiment, a method of treating a reperfusion injury in a subject in need may involve administering a therapeutically effective amount of at least one ghrh agonist peptide to the subject.
06/26/14
20140179223
Wireless power and data transmission
Communications between a base station and a transponder that is powered by the base station are effected using a signal differentiation approach. A first radio frequency signal is communicated between the base station and the transponder to power the transponder, with the first radio frequency signal including noise and data for authenticating communications between the base station and the transponder.
06/26/14
20140178987
Stem cell culture medium and its applications as well as a stem cell culture method
The present invention discloses a stem cell culture medium and its applications as well as a stem cell culture method. The said stem cell culture medium contains no serum.
06/26/14
20140178894
Culture medium suitable for the culture of undifferentiated cells
The present application relates to a composition comprising the components listed in table i in an amount that will lead to the respective concentration specified in table i for each of said component when said composition is diluted with water into 1× medium, said composition being particularly suitable to generate a chemically-defined medium suitable for culturing cells, especially primary cells, maintaining their proliferation and differentiation potential.. .
06/26/14
20140178426
Nucleic acid composition and methods of eliciting an immune response using the same
The present invention provides for novel compositions and methods for delivering genes of interest to stem cells using vectors that contain differentiation-specific transcriptional regulatory elements. For example, stem cells in the internal epithelia could be transfected with a vaccine construct, which has an epithelial cell differentiation-specific promoter driving the expression of viral envelope proteins.
06/26/14
20140178408
Method of producing an antibody
The present invention provides an immunodeficient mouse (nog mouse) suitable for engraftment, differentiation and proliferation of heterologous cells, and a method of producing such a mouse. This mouse is obtained by backcrossing a c.b-17-scid mouse with an nod/shi mouse, and further backcrossing an interleukin 2-receptor γ-chain gene-knockout mouse with the thus backcrossed mouse.
06/19/14
20140171690
Differentiation inducer to brown-like adipocyte of white adipocyte
In which, in formula (1), r1 to r4 represents a hydrogen atom, a hydroxy group, a saturated or unsaturated, linear or branched alkoxy group having 1 to 10 carbon atoms, or a saturated or unsaturated, linear or branched alkyl group having 1 to 10 carbon atoms and r1 to r4 each may be the same or different.. .
06/19/14
20140171380
Screening assays using stem cells and stem cell-derived neurons from mouse models of alzheimer's disease
Successful cns drug discovery requires a scalable, highly physiological neuronal model. Using directed differentiation of mouse embryonic stem (mes) cells, including mes cells isolated from a mouse model of alzheimer's disease (ad), a highly homogeneous primary neuronal model amenable to phenotypic assays for production and synaptotoxicity of amyloid β-peptide was developed.
06/19/14
20140170751
Method for preparing corneal endothelial cell
The present invention relates to a method for preparing corneal endothelial progenitor cells by adherent culturing a cell population isolated from corneal endothelial cell tissue at a low density by using a serum-free medium. The present invention also relates to a method for preparing corneal endothelial cells by differentiation-inducing the corneal endothelial progenitor cells obtained by the aforementioned method.
06/19/14
20140170746
Method for preparing induced pluripotent stem cells using microvesicles derived from embryonic stem cells
Provided is a method of dedifferentiating somatic cells using embryonic stem cell-derived microvesicles. Particularly, a method of preparing induced pluripotent stem cells by treating a composition including embryonic stem cell-derived microvesicles to the somatic cells.
06/19/14
20140170122
Adult stem cells derived from human skin dermis
Provided in the present invention are adult stem cells derived from human skin dermis, and a method for isolating same. Further provided in the present invention are osteoblastic cells and adipocytes differentiated from the adult stem cells derived from human skin dermis, and a differentiation method therefor.
06/19/14
20140166579
Device and method for monitoring an extracorporeal blood circuit for the detection of air bubbles
A device for monitoring an extracorporeal blood circuit of an extracorporeal blood treatment device for detection of air bubbles in blood that is conveyed in the extracorporeal circuit by a blood pump, and a method for monitoring an extracorporeal blood circuit for detection of air bubbles, together with a device for monitoring the extracorporeal blood circuit are described. The device and method are based on monitoring the negative pressure in the extracorporeal blood circuit upstream of the blood pump, to allow differentiation between the occurrence of microbubbles which are attributable to cavitation and an entry of air not due to cavitation.
06/12/14
20140162359
Differentiation of human embryonic stem cells into pancreatic endoderm
The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides methods to produce a population of pancreatic endoderm cells, wherein the initial seeding density of undifferentiated epluripotent cells is defined..
06/12/14
20140160983
Method, system and device for configuring radio access bearers in mobile networks with multi-rab capability
Method and network entities for providing good performance for voice in multirab connection for services of a cs+ps call setup (31) without high throughput necessity but providing good throughput for the services needing it. A differentiation of the multirab configuration (bearer type, mobility parameters and channel switching timers), based on service detection, is performed either in the ran either in the cn indicating eventually this detection to the ran.
06/12/14
20140160542
Novel method of fast fourier transform (fft) analysis using waveform-embedded or waveform-modulated coherent beams and holograms
Method of fast fourier transform (fft) analysis for collecting waveforms and other vibrational intelligence and modulating or embedding same into one or more coherent reference beams of an n-dimensional holographic recording device for producing one or more holograms of objects, including singularity points in space. The result provides wholesale differentiation of waveforms distinguishable from others based on their spectral characteristics.
06/12/14
20140158554
Sensor for detecting stem cell differentiation based on electrochemical methods
This invention relates to a sensor for detecting a stem cell differentiation, including (a) an electrode; and (b) a substrate of an alkaline phosphatase. The phosphorylation or dephosphorylation of the substrate for an alkaline phosphatase as a stem cell undifferentiation marker which dephosphorylates its substrate may be measured using an electrical signal in the present sensor.
06/05/14
20140155461
Molecular targets and compounds, and methods to identify the same, useful in the treatment of bone and joint degenerative diseases
The present invention relates to methods for identifying agents capable of inhibiting the expression or activity of proteins involved in the processes modulating osteoclastogenesis, which inhibition is useful in the prevention and/or treatment of bone and joint degenerative diseases and diseases involving aberrant activity or differentiation of osteoclasts. In particular, the present invention provides methods for identifying agents for use in the prevention and/or treatment of rheumatoid arthritis..
06/05/14
20140155460
Micro-rna's that regulate muscle cells
The present invention describes micrornas that regulate the differentiation, proliferation and death of cardiac and skeletal muscles cells. These molecules represent unique targets in the developmental pathways of muscle cells.
06/05/14
20140155396
C-met modulators and method of use
The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides quinazolines and quinolines which inhibit, regulate, and/or modulate kinase receptor, particularly c-met, kdf, c-kit, flt-3 and flt-4, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions.
06/05/14
20140154728
Compositions, systems and methods based on the differentiation of epicardial cells to typical and atypical fates
Disclosed are epicardium-derived mesenchymal cells (epdcs) that differentiate to fates that are commonly adopted by mesenchymal cells elsewhere in the body, but not currently associated with the epicardium. Also disclosed are methods, systems and assays relating to adipocyte and/or osteogenic differentiation in epdcs that are often related to disease or disregulated states, i.e.
06/05/14
20140154248
Recombinant immunotoxin targeting mesothelin
Mesothelin is a differentiation antigen present on the surface of ovarian cancers, mesotheliomas and several other types of human cancers. Because among normal tissues, mesothelin is only present on mesothelial cells, it represents a good target for antibody mediated delivery of cytotoxic agents.
05/29/14
20140148915
Generating ck19-positive cells with hair-like structures from whartons jelly
A method of differentiating cells into ck19-positive cells capable of producing hair follicle-like and hair structure-like can include: providing a tissue scaffold; seeding cells into the scaffold, the cells being capable of differentiation; incubating the scaffold having the cells in a cell growth media; and incubating the scaffold having the cells in an osteogenic differentiation medium sufficient for ck19-positive cells to be generated in the scaffold. The tissue scaffold can be a decellularized whartons' jelly matrix.
05/29/14
20140148583
Antibody inducing antigen-specific t cell tolerance and use thereof
The present invention relates to an antibody binding to the domain 2 of human intercellular adhesion molecules-1 (icam-1) where the antibody is able to modulate the differentiation status of dendritic cells and induce antigen-specific t cell tolerance, thereby be effective in the prevention and/or treatment of t cell-mediated immune disorders such as transplantation rejection, graft-versus-host disease, and autoimmune disease. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease..
05/29/14
20140148399
Compositions and methods for treating or ameliorating obesity or for reducing diabetic hypercholesterolemia
Obesity is one of the major health concerns in the twenty-first century and is one of the leading causes of preventable death. It is a strong risk factor for type 2 diabetes.
05/29/14
20140148347
High resolution analysis of mammalian transcriptome using gene pool specific primers
The present invention provides methods and systems for analyzing mammalian transcriptomes, particularly, for low abundant transcripts, and with the use of high throughput technologies. Heptamer primers and sequence tags generated by the iterative randomized algorithm, as well as the sequencing-library generation system for amplifying and synthesis-based sequencing low abundant transcripts using the heptamer primers are also provided.
05/29/14
20140147419
Compositions and methods for formation of bone tissue
Provided is a step-wise method of forming an engineered construct. Various embodiments include inducing differentiation of progenitor cells, such as embryonic stem cells; expanding the differentiated progenitor cells; combining the expanded progenitor cells and a biocompatible scaffold comprising a matrix material; and incubating the progenitor cells and the biocompatible scaffold so as to form a bone tissue module..
05/29/14
20140147389
Antigen specific ultrasound contrast medium, a process for the preparation thereof and its uses
The present invention refers to an antigen specific echographic contrast medium for diagnostic and/or therapeutic use, a process for the preparation thereof and its uses in ultrasound diagnostic imaging and in therapy. In particular, a contrast medium according to the invention has proven to be useful in selectively carrying drugs and/or other bio-active principles into a diseased tissues and in releasing the same in site, once bond to such tissue and suitably insonated.
05/29/14
20140144749
Banknote processing device
A banknote processing device includes a differentiating section that differentiates banknotes, a temporary holding section that temporarily stores the differentiated banknotes, banknote storage containers that store the banknotes, and a conveyance route that connects the differentiating section, the temporary holding section, and the banknote storage containers. The processing device is constructed so that when the banknotes stored in the temporary holding section are sent out and stored in the banknote storage containers based on differentiation results of the banknotes by the differentiating section, the banknotes are conveyed from the temporary holding section via the differentiating section, and are stored in any one of the banknote storage containers, or the banknotes are conveyed from the temporary holding section, via a route that does not go through the differentiating section, and are stored in a specific one of the banknote storage containers..
05/22/14
20140143754
System and method for the structuring and interpretation of organic computer programs
In various aspects, a system and method for structuring and interpreting organic computer programs may provide for programs to expand, grow and evolve analogous to the way plants, animals, and organisms in nature grow and evolve. The organic computing system and method may unify program design time and program run time, may provide for program structure and program state to change at run time, and may provide for programs to continuously change and evolve through the addition of member functions, inputs, and outputs as the program is running.
05/22/14
20140142650
Nerve signal differentiation in cardiac therapy
Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes..
05/22/14
20140142122
Substituted triazolo-pyrimidine compounds for modulating cell proliferation, differentiation and survival
Disclosed herein are erythropoietin-mimetic compounds of formula i, which modulate the survival, function, or differentiation of, for example, kidney cells, neurons, erythroid cells, or other erythropoietin-responsive cells. The present invention also relates to compounds and methods that preferentially modulate cells expressing the tissue-protective erythropoietin receptor.
05/22/14
20140141058
Use of oligosaccharide compounds for the prevention and treatment of pathological scars
The present invention relates to a compound selected among the synthetic polysulphated oligosaccharides having 1 to 4 ose units and the salts and complexes thereof to be used for the treatment of wounds resulting in pathological scars selected among hypertrophic, retractile or atrophic scars. Said use is preferred in particular in patients that have a predisposition to developing hypertrophic, retractile or atrophic scars.
05/22/14
20140141050
Bioresorbable wound dressing
The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues.


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Differentiation topics: Differentiation, Stem Cells, Antibodies, Proliferation, Transplant, Smooth Muscle, Heterogeneous, Mesodermal, Cell Differentiation, Metabolism, Nucleic Acids, Therapeutics, Oligodendrocyte, Antagonist, Dysfunction

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