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Diabetes

Diabetes-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Intrinsic chromosomal linkage and disease prediction
February 15, 2018 - N°20180046698

An improved method is the product of an exploration for ways in which to improve the success of genomic disease prediction and presents the elements of more successful prediction tools for the identification of genomic locations of disease based on: genomic labeling it loci as determined by correlated snp linkage as determined from several additional gwas (genome wide association studies) ...
Use of mip-1beta inhibitors for improving angiogenesis to reduce tissue ischemia and rescue diabetic ...
National Yang-ming University Taipei Veternas General Hospital
February 15, 2018 - N°20180044413

The present invention relates to a use of mip-1β inhibitor for promoting angiogenesis in diabetes mellitus patients so as to improve tissue ischemia in damaged area and to prevent diabetic vasculopathy.
Substituted bridged urea analogs as sirtuin modulators
Glaxosmithkline Llc
February 15, 2018 - N°20180044338

Provided herein are novel substituted bridged urea and related analogs and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, ...
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Diabetes Patent Applications
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  • 521+ full patent PDF documents of Diabetes-related inventions.
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Vascular calcification prevention and treatment
Summit Innovation Labs Llc
February 15, 2018 - N°20180042962

The invention encompasses compositions and methods for effectively interfering, reducing and preventing conversion of vascular smooth muscle cells (vsmcs) and circulating stem cells to osteoblastic bone-like cells, thereby reducing and/or preventing vascular calcification (vc) or calcium mineral (hydroxyapatite) deposition in the vasculature. The severity and extent of calcification in the major arteries reflect atherosclerotic plaque burden and strongly predict ...
Metabolic syndrome treatment
Arkay Therapeutics, Llc
February 15, 2018 - N°20180042945

Formulations and methods of providing an orally-active anti-metabolic disease fixed dose combinations (fdc) for use as personalized medicine to treat different components of the metabolic syndrome or insulin resistance syndrome such as type ii diabetes, hypertension, hyperlipidemia and obesity are disclosed. Pharmaceutical compositions of anti-inflammatory centric drug formulations and methods comprising of nsaids in general and selective cox-2 inhibitors in ...
Treatment and prevention of diabetes and obesity
February 15, 2018 - N°20180042287

Since the present compositions are aimed toward normalizing metabolism and energy expenditure and managing oxidative stress and inflammation, they are also beneficial in relation to physical activity, in particular performance, endurance, fatigue and recovery during intensive and continuous exercise/exertion.
Diabetes Patent Pack
Download 521+ patent application PDFs
Diabetes Patent Applications
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inventor
  • 521+ full patent PDF documents of Diabetes-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Fiber-rich maltooligosaccharides having low glucose bioavailability, method of manufacture thereof and use thereof in human ...
Roquette Freres
February 08, 2018 - N°20180037599

The present invention relates to maltooligosaccharides, the content of α-1,4-glycosidic bonds of which is between 70% and 80% of the total number of 1,4-type glycosidic bonds. The invention also relates to the method for manufacturing these maltooligosaccharides. Said maltooligosaccharides afford all the benefits of fiber-based foods, with an extremely low nutritional value. Such a compromise is particularly advantageous for ...
Substituted quinolines as pde-10 inhibitors
Sunovion Pharmaceuticals Inc.
February 08, 2018 - N°20180037590

Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as cns disorders and metabolic disorders, including, but not limited to, e. G., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.
Compounds and methods for inducing browning of white adipose tissue
Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences
February 08, 2018 - N°20180037556

The present invention provides a compound for inducing browning of white adipose tissue in vitro and in vivo of formula i, the preparation method thereof, as well as a composition comprising the same. Further, the present invention also relates to the use of the compound and the method to treat metabolic disorders, such as obesity and diabetes.
Dermatopontin as a therapeutic for metabolic disorders
Agency For Science, Technology And Research
February 08, 2018 - N°20180036371

The present disclosure describes to a method of treating a metabolic disease in a subject, wherein the method comprises administration of dermatopontin to a subject, wherein the dermatopontin is recombinant dermatopontin and the metabolic disease is selected from a group consisting of weight gain, diet-induced weight gain, obesity, morbid obesity, metabolic syndrome, glucose homeostasis, insulin resistance, type i diabetes, type ...
Method for treating hiv
Enzo Therapeutics, Inc.
February 08, 2018 - N°20180036326

The present invention provides novel processes for regulating immune responses in mammalian subjects, e. G., humans, afflicted with diseases such as cancers, infections, e. G., viral infections, bacterial infections, or immune dysfunctions, especially auto-immune disorders, e. G., diabetes, crohn's disease, rheumatoid arthritis, arteriosclerosis and ulcerative colitis. More particularly, this invention relates to generating elevated levels of an intermediary metabolite, e. ...
A method of protecting against carbonyl stress induced ischemia-reperfusion injury in the diabetic brain via ...
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College
February 08, 2018 - N°20180036270

A method for one of preventing and minimizing diabetes pathology in a mammal, comprising administering to the mammal an effective amount of n-acetylcysteine (nac).
No donors for the treatment of impaired tissue perfusion
Mirandapharmaceuticals Ag
February 08, 2018 - N°20180036259

A method for treatment of prophylaxis of a chronic disease or condition associated with impaired tissue or organ perfusion, comprising administering an amino-c2-c6-alkyl nitrate, an amino-c2-c4-alkyl nitrate, or a pharmaceutically acceptable salt thereof, to a patient in need thereof. The disease or condition is a micro- and/or macro-vascular disease selected from the group of diseases ...
Diabetes Patent Pack
Download 521+ patent application PDFs
Diabetes Patent Applications
Download 521+ Diabetes-related PDFs
For professional research & prior art discovery
inventor
  • 521+ full patent PDF documents of Diabetes-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Aptamers and sensing technology used for detection of glycated hemoglobin in whole blood
Alfaisal University
February 01, 2018 - N°20180031578

High affinity dna aptamers seq id#1-8 for hba1c and thb were successfully selected using selex after 11 rounds of selection. The tested aptamers bind to hba1c with dissociation constants in the nanomolar range with the highest affinity aptamer, seq id#6, exhibiting a kd of 2. 8 nm. Another aptamer sequence (seq id #4) which showed high binding affinity to thb with ...
Devices for detection of antibodies against therapeutic drugs
February 01, 2018 - N°20180031569

Devices for detection of antibodies against therapeutic drugs (adas), in which chimeric proteins facilitate immobilization and exposure of target epitopes, are described. Results can be obtained in minutes, enabling point of care testing and/or patient self-testing, and risk assessment. The data can also be used for deriving scientific knowledge in the fields of oncology, autoimmune diseases (including but not ...
Devices, solutions and methods for sample collection related applications, analysis and diagnosis
Abogen, Inc.
February 01, 2018 - N°20180031543

A solution is described for preserving cells and/or extra-cellular components in naturally expressed bodily fluids (e. G. Saliva, sputum, urine) for further downstream analysis and/or for diagnosis of a medical condition. The solution may be hypertonic with respect to blood. Techniques are described for enriching cells from a sample of a naturally expressed bodily fluid, and/or for ...
Diagnostic methods, therapeutic agents and uses thereof
Metabolon, Inc.
February 01, 2018 - N°20180031541

The present invention provides a method for diagnosing a disease or disorder selected from the group consisting of insulin resistance, a metabolic disorder, diabetes and pre-diabetes in a subject. The method comprises the step of determining the level of a compound represented by structural formula (vi): or a salt thereof. Compositions and method of making thereof are also described.
Puma, a pro-apoptotic gene, as a novel molecular biomarker for tnfalpha-induced human islet damage
Hitachi Chemical Co., Ltd.
February 01, 2018 - N°20180030537

P53-upregulated modulator of apoptosis (puma) is a biomarker associated with islet cell health. If puma is low, islet cells are typically healthy. If puma is high, islet cells are typically unhealthy or dying. Puma may be measured by either measuring its nucleic or amino acid. Puma mrna may be induced by tnf-α stimulation in a time- and ...
Compositions and methods for treating fatty tissue buildup
Mhs Care-innovation Llc
February 01, 2018 - N°20180030133

The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type ii diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
Apelin fusion proteins and uses thereof
Regeneron Pharmaceuticals, Inc.
February 01, 2018 - N°20180030099

The invention provides a fusion protein or polypeptide comprising an apelin peptide fused to a multimerizing component. The invention also provides a fusion protein or polypeptide comprising an apelin peptide fused to an fc domain, a fragment of an fc domain, or a variant of an fc domain. Apelin fc-fusion polypeptides are capable of binding to the apelin receptor (aplnr). ...
Crystal form a of compound and preparation method thereof
Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences
February 01, 2018 - N°20180030066

The present invention relates to crystal form a of a compound. The present invention also discloses a preparation method and a pharmaceutical composition of the crystal form a. The crystal form a has strong hypoglycemic activity in vivo and is expected to be a novel pharmaceutically active ingredient for treating or preventing type ii diabetes and/or complications of type ...
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