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Diabetes

Diabetes-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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System and method for assessing quantities or sizes of lipoprotein particles from lipoprotein particle compositions
True Health Ip Llc
November 30, 2017 - N°20170343464

This application discloses methods for assessing quantities of spherical or substantially spherical lipoprotein particles or portions thereof present in a biological sample based on the measurement of free cholesterol and/or phospholipid content in the lipoprotein particles. Methods of treating a subject at increased risk for cardiovascular disease and/or cardiodiabetes are also disclosed.
Hepatocyte based insulin gene therapy for diabetes
Wisconsin Alumni Research Foundation
November 30, 2017 - N°20170342441

A method and vectors for controlling blood glucose levels in a mammal are disclosed. In one embodiment, the method comprises the steps of: treating the hepatocyte cells of a patient with a first, second or third vector, wherein the first vector comprises a promoter enhancer, glucose inducible regulatory elements, a liver-specific promoter, a gene encoding human insulin with modified peptidase ...
Use of microrna precursors as drugs for inducing cd34-positive adult stem cell expansion
Wisconsin Alumni Research Foundation
November 30, 2017 - N°20170342418

This invention generally relates to a composition and its production method useful for developing drugs/vaccines and/or therapies against a variety of degenerative diseases in humans. Particularly, the present invention teaches the essential steps of production and purification processes necessary for producing small hairpin-like rna (shrna) compositions, such as microrna precursors (pre-mirna) and short interfering rnas (sirna), which are ...
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Diabetes Patent Applications
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  • 521+ full patent PDF documents of Diabetes-related inventions.
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Methods and compositions to treat type-1 and type-2 diabetes
Cornell University
November 30, 2017 - N°20170342097

The present disclosure is directed to novel methods of treating type-1 or type-2 diabetes by inactivating tlr2 and tlr4 genes together in cells capable of producing insulin and/or regenerating β cells, and providing the cells to a subject in need thereof.
Pyrazino[2,3-b]pyrazine mtor kinase inhibitors for oncology indications and diseases associated with the mtor/...
Cornell University
November 30, 2017 - N°20170342080

Wherein r1-r4 are as defined herein, compositions comprising an effective amount of a heteroaryl compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions, comprising administering an effective amount of a heteroaryl compound to a patient in need thereof.
A multi-state ratchet mechanism for drug injection devices
Novo Nordisk A/s
November 30, 2017 - N°20170340836

The present invention relates in a first aspect to a multi-state ratchet mechanism for a drug injection device. The multi-state ratchet mechanism comprises a ratchet gear member and a cooperating ratchet pawl member. An annular inner surface of the ratchet gear member comprises a first ring shaped surface portion with a first predetermined cross-sectional profile comprising a first asymmetrical toothing ...
Diabetes Patent Pack
Download 521+ patent application PDFs
Diabetes Patent Applications
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For professional research & prior art discovery
inventor
  • 521+ full patent PDF documents of Diabetes-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Non-reducing end unsaturated mannuronic acid oligosaccharides and compositions containing same as active ingredient
Industry Foundation Of Chonnam National University
November 30, 2017 - N°20170340660

Disclosed is a non-reducing end unsaturated mannuronic acid oligosaccharide having a molecular weight of 100-3000 da, which is obtained by lysing polymannuronate as a substrate with alginate lyase, and provided are: a non-reducing end unsaturated mannuronic acid oligosaccharide; and pharmaceutical compositions for alleviating, preventing, or treating obesity, diabetes, and climacteric syndrome, and probiotics for promoting intestinal beneficial bacteria, the compositions ...
Bromocriptine formulations
Veroscience Llc
November 30, 2017 - N°20170340632

The present application describes pharmaceutical formulations of bromocriptine mesylate and methods of manufacturing and using such formulations. The formulations are useful for improving glycemic control in the treatment of type 2 diabetes.
Alpha-cell re-generation combined with conversion to beta cells
Universite De Nice Sophia Antipolis-grand ChÂteau
November 30, 2017 - N°20170340591

The present invention relates to methods of generating a population of beta cells from a population of alpha cells, by contacting said population of alpha cells with gaba or a gaba receptor agonist, in combination with a monoclonal glucagon neutralizing antibody or other alpha cell mass regulating compounds, for an improved diabetes therapy.
Methods for identifying responders to dopaminergic neuronal enhancing therapies for the treatment of elevated heart ...
Veroscience Llc
November 30, 2017 - N°20170340271

Methods for identifying responders to agents that increase brain dopaminergic neuronal activity for the treatment of metabolic and cardiovascular disease and for treating elevated heart rate and metabolic disease or dysglycemia in subjects with type 2 diabetes.
Anti-acth antibodies and use thereof
Alder Biopharmaceuticals, Inc.
November 23, 2017 - N°20170334987

The present invention is directed to antibodies and fragments thereof having binding specificity for acth. Another embodiment of this invention relates to the antibodies binding fragments thereof described herein, comprising the sequences of the vh, vl and/or cdr polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-acth antibodies and binding fragments thereof conjugated ...
Thienopyranones as kinase and epigenetic inhibitors
Signalrx Pharmaceuticals, Inc.
November 23, 2017 - N°20170334925

The invention relates to methods of treating diseases including but not limited to, cancer, non-cancer proliferative disease, sepsis, autoimmune disease, viral infaction, atheroscleosis, type 1 or 2 diabetes, obesity, inflammatory disease, or myc-depenent disorder including by modulating biological processes by the inhibition of pi3 kinase and/or bromodomain protein binding to substrates comprising the administration of a compound(s) of formula i-ix (...
New pyrazolopyrimidine derivatives as nik inhibitors
Janssen Pharmaceutical Nv
November 23, 2017 - N°20170334915

The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of nf-κb-inducing kinase (nik—also known as map3k14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, to ...
Diabetes Patent Pack
Download 521+ patent application PDFs
Diabetes Patent Applications
Download 521+ Diabetes-related PDFs
For professional research & prior art discovery
inventor
  • 521+ full patent PDF documents of Diabetes-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
New pyrazole derivatives as nik inhibitors
Janssen Pharmaceutica Nv
November 23, 2017 - N°20170334900

The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of nf-κb-inducing kinase (nik—also known as map3k14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, to ...
Compounds and methods for activating the apoptotic arm of the unfolded protein response
Sanford-burnham Medical Research Institute
November 23, 2017 - N°20170334889

N-substituted sulfonylphenyl-5-nitrofuranyl-2-carboxamide derived compounds, which selectively activate the apoptotic, but not the adaptive arm, of the unfolded protein response are provides as is their use in the treatment of diseases such as diabetes, alzheimer's, parkinson's, hemophilia, lysosomal storage diseases and cancer.
Pyrazole compounds
Eli Lilly And Company
November 23, 2017 - N°20170334885

This invention relates to pyrazole compounds or pharmaceutically acceptable salts thereof. Compounds of this invention are inhibitors of methionine aminopeptidase 2 (metap2) and dipeptidyl peptidase-4 (dpp-4). Metap2 is a metalloproteinase that cleaves initiator methionine from nascent peptide emerging from the ribosomes. Wo 2010/065879 reports small molecule metap2 inhibitors for obesity treatment. Dpp-4 inhibitors are an established drug class to improve glycemic control ...
Novel mitochondrial uncouplers for treatment of metabolic diseases and cancer
Eli Lilly And Company
November 23, 2017 - N°20170334869

The present disclosure relates to benzamide compounds, prodrugs of the compounds, pharmaceutical compositions containing the compounds and/or the prodrugs and methods of using the compounds, prodrugs and pharmaceutical compositions in the treatment of diseases related to lipid metabolism including diabetes, non-alcholic fatty liver disease (nafld), non-alcholic steathohepatitis (nash), diseases caused by abnormal cell proliferation including cancer, psoriasis, and infectious ...
Novel approach to treatment of hyperglycemia using a nanoparticle encapsulated peptide
University Of Rochester
November 23, 2017 - N°20170333564

The present invention relates to compositions and methods for treating or preventing hyperglycemia and diseases associated with hyperglycemia. In certain embodiments, the composition comprises a peptide having the amino acid sequence krscyk wherein the peptide consists of d-amino acids is useful in treating or preventing diabetes. In some aspects, the peptide of the invention is encapsulated in a nanoparticle.
Methods for treating and/or limiting development of diabetes
Biocrine Ab
November 23, 2017 - N°20170333555

The present invention provides methods for identifying candidate compounds for limiting development of and/or treating diabetes, and methods for limiting development of and/or treating diabetes.
Pharmaceutical composition, methods for treating and uses thereof
Boehringer Ingelheim International Gmbh
November 23, 2017 - N°20170333465

The present invention relates to certain sglt-2 inhibitors for treating, preventing, protecting against and/or delaying the progression of chronic kidney disease in patients, for example patients with prediabetes, type 1 or type 2 diabetes mellitus.
Salts and compositions useful for treating disease
Regents Of The University Of Minnesota
November 23, 2017 - N°20170333417

The invention provides a combination or salt of lipoic acid and a compound of formula (i): the combinations and salts are useful for treating diabetes.
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