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Composition of a first non-labeled monoclonal antibody binding to a tumor antigen and a non-cross reactive second monoclonal antibody labeled with a nir fluorescence label
This invention relates to a composition of a non-labeled monoclonal antibody binding to a tumor antigen and a second monoclonal antibody labeled with a NIR fluorescence label, binding to the same tumor antigen, wherein the first and second antibody exhibit no cross reactivity. The composition can be used for the treatment...

Devices and methods and systems for determining and/or indicating a medicament dosage regime
In one aspect, the disclosure is directed to a device for determining and/or indicating a medicament dosage regime. The device may include a housing, a processor, a memory, an input device, and/or an indication device. The dosage determining and/or indicating device is configured for receiving user, e.g., patient, information, medicament information,...

Virus-like particles comprising composite capsid amino acid sequences for enhanced cross reactivity
The present invention provides polypeptides having a composite amino acid sequence derived from a consensus sequence representing the capsid proteins of two or more circulating strains of a non-enveloped virus. In particular, the invention provides virus-like particles comprising at least one composite polypeptide. Such virus-like particles have antigenic epitopes of two...

Optimized influenza vaccines
The invention concerns nucleotides vaccines encoding influenza proteins with few or no glycosylation sites. Since these first introductions of pandemic influenzas the viruses have drifted, accumulating mutations at antigenic sites, but also the N-glycosylation pattern has changed during the drifted years, accumulating N-linked glycosylation sequons that help mask the antigenic sites...

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Cross Reactivity patents

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