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This page is updated frequently with new Corneal-related patent applications. Subscribe to the Corneal RSS feed to automatically get the update: related Corneal RSS feeds. RSS updates for this page: Corneal RSS RSS


Systems using eye mounted displays

Date/App# patent app List of recent Corneal-related patents
07/24/14
20140205604
 Antigen binding constructs patent thumbnailAntigen binding constructs
The present invention is directed to antigen binding constructs comprising one or two epitope binding domains separated by a single chain fc region of an antibody, wherein each epitope binding domain in capable of binding to vegf, to dimers comprising two antigen binding constructs of the invention, pharmaceutical compositions comprising said dimers and their use in the treatment of diseases associated with vegf signalling, such as diabetic macular edema (dme), wet age-related macular degeneration (wet amd). Diabetic retinopathy, retinal vein occlusion (rvo), and corneal neovascularisation, and polynucleotide sequences encoding said antigen binding constructs..
07/24/14
20140205563
 Compositions derived from stem cell released molecules & methods for formulation thereof patent thumbnailCompositions derived from stem cell released molecules & methods for formulation thereof
Compositions for use in treatment of a variety of tissue diseases include stem cells and stem cell released molecules (srm's) suspended in an aqueous solution with a cellulosic material or other thickening agent. The stem cells and srm's can be derived from one or more distinct cell lines.
07/24/14
20140204003
 Systems using eye mounted displays patent thumbnailSystems using eye mounted displays
A display device is mounted on and/or inside the eye. The eye mounted display contains multiple sub-displays, each of which projects light to different retinal positions within a portion of the retina corresponding to the sub-display.
07/17/14
20140200665
 Anterior corneal shapes and methods of providing the shapes patent thumbnailAnterior corneal shapes and methods of providing the shapes
Methods of determining a desired shape for the anterior surface of the cornea in vision correction procedures.. .
07/10/14
20140194957
 Ophthalmic treatment device, system, and method of use patent thumbnailOphthalmic treatment device, system, and method of use
Ophthalmic treatment systems and methods of using the systems are disclosed. The ophthalmic treatment systems include (a) a light source device; (b) at least one optical treatment head operatively coupled to the light source device, comprising a light source array, and providing at least one treatment light; and (c) a light control device, which (i) provides patterned or discontinuous treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye); or (ii) adjusts intensity of part or all of the light source array, providing adjusted intensity treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye).
07/10/14
20140193466
 Silk compositions and methods of using same patent thumbnailSilk compositions and methods of using same
The present invention provides for silk-derived compositions for treating a wide variety of ocular conditions. The composition is produced by processing the silk cocoon into a water-based solution (i.e., a dissolved silk), which is then cast into a film.
06/26/14
20140180265
 Ophthalmological laser method and apparatus patent thumbnailOphthalmological laser method and apparatus
The present invention relates to a femtosecond laser ophthalmological apparatus and method that creates a flap on the cornea for lasik refractive surgery or for other applications that require removal of corneal and lens tissue at specific locations such as in corneal transplants, stromal tunnels, corneal lenticular extraction and cataract surgery. The femtosecond laser is transferred to a hand piece module via a rotating mirror arm module.
06/26/14
20140176904
 Ophthalmic aberrometer capable of subjective refraction patent thumbnailOphthalmic aberrometer capable of subjective refraction
The present invention contemplates an ophthalmic aberrometer combining measurements of wavefront aberrations and subjective refraction into a single instrument and refers both measurements to the same corneal plane the present invention also contemplates an ophthalmic aberrometer employing an open field and subjective correction to overcome instrument myopia and to ensure accurate measurement of the best-corrected visual acuity in addition to measurement of wavefront aberrations. The present invention further contemplates an ophthalmic aberrometer implementing an optical relay with adjustable optical power compensation to eliminate the need for flipping plurality sets of trial lenses for defocus correction.
06/19/14
20140171928
 Corneal multi-plane incision using a surgical laser setup calculations interface patent thumbnailCorneal multi-plane incision using a surgical laser setup calculations interface
An apparatus and a method are described for setting up a medical laser machine configured to be used in eye surgery for making a multi-planar incision. In various embodiments, a software interface is provided to receive, from a user, one or more dimensional measurements of an eye of a patient as input, automatically calculate precise geometric and other setup parameters, based on a set of equations, of a multi-planar incision for the patient's eye, and provide the calculated parameters to the user for setting up the medical laser machine to make the incision..
06/19/14
20140171661
 Reduced central corneal thickening by use of hydrophilic ester prodrugs of beta-chlorocyclopentanes patent thumbnailReduced central corneal thickening by use of hydrophilic ester prodrugs of beta-chlorocyclopentanes
Compositions and methods for treating glaucoma are provided. In particular hydrophilic ester prodrugs and their use to reduce central corneal thickening is provided..
06/19/14
20140170751
Method for preparing corneal endothelial cell
The present invention relates to a method for preparing corneal endothelial progenitor cells by adherent culturing a cell population isolated from corneal endothelial cell tissue at a low density by using a serum-free medium. The present invention also relates to a method for preparing corneal endothelial cells by differentiation-inducing the corneal endothelial progenitor cells obtained by the aforementioned method.
06/19/14
20140168605
Large diopter range real time sequential wavefront sensor
Example embodiments of a large dynamic range sequential wavefront sensor for vision correction or assessment procedures are disclosed. An example embodiment optically relays a wavefront from an eye pupil or corneal plane to a wavefront sampling plane in such a manner that somewhere in the relaying process, the wavefront beam from the eye within a large eye diopter range is made to reside within a desired physical dimension over a certain axial distance range in a wavefront image space and/or a fourier transform space.
06/12/14
20140163535
Compensation systems and methods for flap induced aberrations
Embodiments of the present invention encompass systems and methods for customized vision treatments that account for effects associated with corneal flap creation.. .
06/05/14
20140155875
After-treatment of refraction correction by ophthalmic surgery
A planning system for generating control data, a treatment device for ophthalmic surgery to correct refraction, and a method for generating control data for such a treatment device, by which method it is easily possible to continue an interrupted treatment or correct a previous treatment. To this end, the planning system has calculating means for defining a corneal incision surface, wherein the calculating means determine the new corneal incision surface such that the existing corneal incision surface is incised by at least a part of the new corneal incision surface at an angle of between 60° and 120°..
06/05/14
20140155874
Laser system and method for correction of induced astigmatism
There is provided a system, apparatus and methods for developing laser systems that can create precise predetermined clear corneal incisions that are capable of reducing induced astigmatism. The systems, apparatus and methods further provide laser systems that can provide these incisions at or below bowman's membrane..
06/05/14
20140155872
High-order optical correction during corneal laser surgery
Systems and methods related to corneal ablation for treatment of one or more high-order optical aberrations are provided. A method includes providing a defect-correcting prescription, determining an ablation profile to impose the prescription on the cornea, and determining a sequence of laser-energy ablations to impose the ablation profile on the cornea.
06/05/14
20140155871
Method for preparing corneal donor tissue for refractive eye surgery utilizing the femtosecond laser
A method of accurately fabricating a non-human donor corneal tissue for implantation into a recipient human cornea, the method comprising the steps of: removing corneal tissue from a donor with a femtosecond laser; placing the corneal tissue in a fixative solution for a selected time interval to cross-link the collagen fibrils in the tissue and prevent swelling of the corneal tissue; and shaping the tissue to provide a conical inlay of a selected shape and thickness having one or more radial extensions. The method is such that the corneal inlay may be attached to the peripheral corneal and/or the sclera.
06/05/14
20140155870
Shielded intraocular probe for improved illumination or therapeutic application of light
An intraocular light probe has a mask or shield affixed at its distal end thereof which forms a directed light beam for intraocular application of light to target tissues or intraocular application of therapeutic light. The mask or shield serves to more fully focus, intensify and direct the beam toward the target tissues.
06/05/14
20140155800
Eye coverings for corneal healing and methods of use
Methods for providing faster visual and functional recovery of patients following ocular therapy such as ocular therapy involving manipulation of the ocular tissue and/or associated with a lesion external to the optical region and ocular therapy involving incising the ocular tissue and implanting a device within the optical region are disclosed. Methods of healing a trauma wound to a cornea and methods of protecting an eye of a patient from potential injury are also disclosed.
05/29/14
20140148486
Sodium channel blocker delivery system with scleral lens
A scleral lens is provided with a sodium channel blocker or a sodium channel modulator disposed in the pre-corneal tear film between the scleral lens and the cornea. This system can be used to deliver sodium channel blockers or a sodium channel modulators not currently used because of poor bioavailability.
05/22/14
20140142599
Device for assisting in the preparation of an operation on the human eye
According to an exemplary embodiment, a device (12) for assisting in the preparation of an operation on the human eye (14) for the purpose of generating a corneal flap by means of a microkeratome system (10) includes: an input interface arrangement (50) that permits at least the input of data relating to a set value of at least one flap parameter and also to at least one patient-related parameter; a computer (46) that has been set up to access a stored data collection (44) of several surgical data records, each of which includes a post-operative actual value of at least one flap parameter, a value for at least one patient-related parameter and configuration data of the microkeratome system, the computer (46) having been set up to ascertain, on the basis of the data collection (44) in a manner depending on the input data, configuration information that represents a proposed configuration of the microkeratome system (10); an output interface arrangement (48) for outputting the configuration information.. .
05/22/14
20140142587
Medical tools for small incision eye surgery
Systems, devices and methods for performing small incision dlek include providing a corneal transplantation donor tissue graft; then forming the tissue graft into an implantable configuration using the flexible substrate. Related medical kits and tools for forming a compact or rolled donor tissue graft are also described..
05/22/14
20140142560
Ophthalmic surgical device for capsulotomy
A surgical device and procedure are provided for performing microsurgery, including a capsulotomy of a lens capsule of an eye. The device has an elastically deformable cutting element mounted within an elastomeric suction cup.
05/15/14
20140135915
Corneal implant applicators
Devices and methods for handling and depositing corneal implants onto corneal tissue. Devices and methods for packaging and storing corneal implants..
05/15/14
20140135750
Adaptable patient interface
Systems and methods are described for stabilizing an eye for an ocular laser procedure while minimizing corneal distortions which can adversely affect a surgical laser beam. For the systems, a patient interface includes a contact element for stabilizing the eye and establishing a conformal interface with the anterior surface of the cornea.
05/08/14
20140127803
Ips cell having differentiation propensity for corneal epithelium
A major object of the present invention is to provide a method for inducing cell differentiation into corneal epithelial stem cells and/or corneal epithelial cells, for the easy production of a corneal epithelial cell sheet having superior safety in view of the possibility of vascularization and the like occurring. A method for inducing differentiation of a pluripotent stem cell into a corneal epithelial stem cell and/or a corneal epithelial cell, the method comprising the step of culturing a pluripotent stem cell in the presence of a stromal cell or an amnion-derived factor..
05/08/14
20140125955
Method for optimized prediction of the postoperative anatomical position of an intraocular lens implanted in a pseudopakic eye
Postoperative lens position is predicted on the basis of known measured values, such as the corneal thickness, the depth of the anterior chamber, the eye length, and the distances of the capsular bag equator and/or of the lens haptic from the anterior surface of the lens. In addition, the calculation also takes into account the attitude of the intraocular lens, for which purpose additional parameters of the pseudophakic eye are used that have not previously been taken into consideration.; the proposed method is suitable for a more exact prediction of the strength and nature of an intraocular lens to be implanted in a pseudophakic eye in the context of cataract surgery or of a refractive intervention.
05/01/14
20140121769
Apparatus, system, and method for intraocular lens power calculation using a regression formula incorporating corneal spherical aberration
An intraocular lens, and a system and method of providing an intraocular lens, having at least one characteristic of the intraocular lens customized in accordance with a modified regression that includes a modification for corneal spherical aberration. The lens, system and method may indicate measuring at least one biometric parameter of an eye at a desired light level, determining a desired postoperative condition of the eye, obtaining a corneal spherical aberration of the eye, applying at least one empirically derived regression calculation, and predictively estimating, in accordance with an output of the at least one empirically derived regression calculation, the at least one characteristic of the intraocular lens to obtain the desired postoperative condition.
05/01/14
20140121654
Surgical laser setup calculations interface for corneal multi-plane incision
An apparatus and a method are described for setting up a medical laser machine configured to be used in eye surgery for making a multi-planar incision. In various embodiments, a software interface is provided to receive, from a user, one or more dimensional measurements of an eye of a patient as input, automatically calculate precise geometric and other setup parameters, based on a set of equations, of a multi-planar incision for the patient's eye, and provide the calculated parameters to the user for setting up the medical laser machine to make the incision..
05/01/14
20140118699
Method for calculating tear film lipid and aqueous layer thicknesses and corneal surface refractive index from interferometry data
Disclosed herein is a method of calculating tear film lipid and aqueous layer thicknesses and/or corneal surface refractive index from interferometry data obtained from simultaneous measurements of the aqueous and lipid layers of the tear film along with a measurement of the corneal surface reflectance.. .
04/24/14
20140114335
Surgical hand piece with dual lumen work tip for use with infusion cannula
A surgical hand piece has a source of ultrasonic energy provided to a connecting body having a first passage with one end to receive fluid from a first source and the other end at the connecting body distal end. A work tip has first and second tubes each having at least one opening at its distal end and the proximal end of one or both of the tubes connected to the connecting body distal end to receive the ultrasonic energy and to selectively receive or discharge fluid from either the first or second source as controlled by a valve.
04/24/14
20140114297
Graphical user interface for laser eye surgery system
Methods and systems for planning and forming incisions in a cornea, lens capsule, and/or crystalline lens nucleus are disclosed. A method includes measuring spatial dispositions, relative to a laser surgery system, of at least portions of the corneal anterior and posterior surfaces.
04/24/14
20140114296
Graphical user interface for laser eye surgery system
Methods and systems for planning and forming incisions in a cornea, lens capsule, and/or crystalline lens nucleus are disclosed. A method includes measuring spatial dispositions, relative to a laser surgery system, of at least portions of the corneal anterior and posterior surfaces.
04/24/14
20140114232
Apparatus for the treatment and/or prevention of corneal diseases
An apparatus for the treatment and/or prevention of corneal diseases includes an applicator head. The applicator head includes a radiation source capable of exciting a non-toxic chromophore.
04/24/14
20140113009
Controlled application of cross-linking agent
According to aspects of the present disclosure, a kit for transepithelial delivery of a cross-linking agent to a cornea includes a first vessel containing an initial formulation that includes a cross-linking agent and a first active ingredient configured to open corneal epithelial tight junctions when applied to a cornea and one or more second vessels each containing a respective secondary formulation that includes the cross-linking agent for application to the cornea after the initial formulation is applied to the cornea.. .
04/17/14
20140107778
Intrastomal segment
A description has been provided herein of an intrastromal segment especially designed for use as a prosthesis inside the corneal tunnel of patients suffering from keratoconus. The segment consists of a lengthened body of variable dimensions in the form of an arc with noticeably rounded ends, devoid of any communicating orifice, and endowed with a transverse section that may be triangular, trapezoidal, hexagonal or oval, with at least three marks connecting to the narrowest side for which two ends aid the safe handling of the segment and the mid-section mark serves as a positional reference point.
04/17/14
20140107633
Re-treatment for ophthalmic correction of refraction
A planning device generating control data for a treatment apparatus for refraction-correcting ophthalmic surgery is provided, said apparatus using a laser device to separate a corneal volume, which is to be removed for correction, from the surrounding cornea by at least one cut surface in the cornea of an eye, said planning device comprising an interface for receiving corneal data including information on pre-operative cuts which were generated in a previous ophthalmic operation, and computing means for defining a corneal cut surface which confines the corneal volume to be removed, said computing means defining the corneal cut surface on the basis of the corneal data and generating a control dataset for the corneal cut surface for control of the laser device.. .
04/17/14
20140107631
Annular keratopigmentation systems and methods of vision correction of presbyopic eyes
Systems, devices, and methods for correcting presbyopic vision create a dye ring in the cornea. The intrastromal ring is created using a femtosecond laser and is centered on the visual axis.
04/17/14
20140107025
Ocular drug delivery system
An ocular drug delivery system including a composition in which a formulation having an active agent such as rhgh and or an rhgh mimic, e.g., that increases insulin growth factor (igf) or that alters insulin growth factor binding protein (igfbp) in a subject is dispersed in a pharmaceutical carrier. The composition is configured for placement in, around or on an eye of the subject, and the composition provides controlled release of an amount of the active agent to the eye effective to promote ocular surface and corneal neural regeneration and wound healing..
04/17/14
20140104574
Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography
Ocular surface interferometry (osi) devices, systems, and methods are disclosed for measuring a tear film layer thickness (tflt) of the ocular tear film, including the lipid layer thickness (llt) and/or the aqueous layer thickness (alt). The tflt can be used to diagnose dry eye syndrome (des).
04/17/14
20140104563
Lenses, devices, methods and systems for refractive error
The present disclosure is directed to lenses, devices, methods and/or systems for addressing refractive error. Certain embodiments are directed to changing or controlling the wavefront of the light entering a human eye.
04/10/14
20140100556
Method and systems for laser treatment of presbyopia using offset imaging
An ophthalmic surgery system and method for treating presbyopia by performing ablative photodecomposition of the corneal surface. The offset image of a variable aperture, such as a variable width slit and variable diameter iris diaphragm, is scanned in a preselected pattern to perform ablative sculpting of predetermined portions of a corneal surface.
04/10/14
20140099290
Endothelial scaffolds
Provided herein is an endothelial scaffold comprising, consisting of, or consisting essentially of decellularized corneal stroma. In some embodiments, the scaffold has cultured endothelial cells seeded thereon.
04/10/14
20140098342
System and method for corneal irradiation
A device and method for use thereof to illuminate a visual system of a subject includes a light-transforming optical element configured to transform a substantially collimated beam of light into light having a diverging spatial distribution. Optionally, light having such spatial distribution includes a plurality of diverging beams of light.
04/10/14
20140098198
Apparatus and method for eye tracking
A gaze tracking apparatus and method are provided that may calculate a three-dimensional (3d) position of a user using at least two wide angle cameras, may perform panning, tilting, and focusing based on position information of the user and eye region detection information, using a narrow angle camera, may detect pupil center information and corneal reflected light information from an eye image acquired through an operation of the narrow angle camera, and may finally calculate gaze position information from the pupil center information and the corneal reflected light information.. .
04/03/14
20140094907
Implantation device for intrastromal prostheses
A device has been described here which is used as a means of implanting an intrastromal prosthesis, consisting of a segment or ring, on the inside of the patient's corneal tunnel. The implanting device eliminates the need to use conventional forceps and includes for this purpose an injector with a support track for the implant segment, attached to a ring carrier piece coupled to the first end of a cylinder base or tunnel.
04/03/14
20140094519
Lipoxin analogs as novel inhibitors of angiogenesis
The present invention is generally drawn to novel isolated therapeutic agents, termed lipoxins, generated from the interaction between a dietary omega-6 polyunsaturated fatty acid (pufa) such as arachidonic acid (aa), oxygenases and the analgesic aspirin (asa). Surprisingly, careful isolation of compounds generated from the combination of components in an appropriate environment provide di- and tri-hydroxy containing derivatives of aa containing compounds having unique structural and physiological properties.
04/03/14
20140092361
Non-contact type tonometer
A non-contact type tonometer includes: a measurement unit including a first measuring unit for measuring an eye pressure of an examinee's eye in a non-contact manner and a second measuring unit for measuring a corneal thickness of the examinee's eye in a non-contact manner; a moving mechanism for causing relative movement of the measurement unit with respect to the examinee's eye; a drive controller for driving the moving mechanism for aligning the measurement unit; and a setting switch controller for switching an alignment reference on the cornea used for aligning the measurement unit between first and second alignment references. The first alignment reference is a reference for measuring the eye pressure with the first measuring unit and the second alignment reference is a reference for measuring the corneal thickness with the second measuring unit and set closer to a corneal rear surface than the first alignment reference..
04/03/14
20140092359
Progressive multifocal rigid gas permeable contact lens
A contact lens is provided. It is a rigid gas permeable, corneal-scleral progressive, multifocal, vision lens that covers the cornea and a portion of the sclera of an eye.
03/27/14
20140085451
Gaze detection apparatus, gaze detection computer program, and display apparatus
A gaze detection apparatus includes a light source which illuminates a user's eye, an imaging unit which generates an image by capturing the image of a user's face, and a processor adapted to: estimate a distance between the imaging unit and the user's face; calculate the ratio of the distance between the imaging unit and the user's face to a separation distance between the imaging unit and the light source and determine, based on the ratio, whether a bright pupil phenomenon occurs; detect from the captured image a corneal reflection image of the light source and a center of the user's pupil when determining that the bright pupil phenomenon does not occur; and detect the user's gaze direction or gaze position based on a positional relationship between the center of the user's pupil and the corneal reflection image when determining that the bright pupil phenomenon does not occur.. .
03/20/14
20140080765
Novel metalloprotein and process for producing same, and prophylactic or therapeutic agent for corneal and conjunctival diseases comprising said metalloprotein
Selenium-lactoferrin according to the present invention has an excellent therapeutic effect on corneal and conjunctival diseases, and is suitable for mass production on an industrial scale.. .
03/20/14
20140078470
Automatic refracto-keratometer
An auto refracto-keratometer not only produces a black-and-white image for observing the alignment of eyes to be examined using an infrared illumination light but also has a color observation optical system for observing a condition of eyes to be examined using color-illumination light. The auto refracto-keratometer comprises an infrared optical system for examining an alignment and corneal curvature of eyes to be examined; a fogging optical system for relaxing accommodation of the eyes; a measuring optical system for measuring refractive power of the eyes; and a color observation optical system having a visible light source for emitting at least one visible light to the eyes and a 2-dimensional imaging device for detecting image of visible light reflected by the eyes..
03/13/14
20140074232
Implantable device for molding the curvature of the cornea
The present invention relates to an intrastromal corneal device for reshaping the curvature of the cornea comprising a substantially circular structure having a convex surface provided with openings for biological exchange between the layers of the cornea, said substantially circular structure comprising the shape of a circular segment or of a spherical/aspheric cap provided or not with a central opening. Said device further comprises means for promoting the reshaping of the cornea, so that it assumes a curvature closer to the intended curvature, thus providing a significant reduction of visual disturbances caused by corneal ectatic conditions such as keratoconus..
03/13/14
20140074231
Biocompatible compositions and methods of manufacture
This disclosure describes, in one aspect, a method that generally includes combining a silica precursor and a biocompatible polymer under conditions effective for the silica precursor and the biocompatible polymer to form a gel, at least partially dehydrating the gel, and rehydrating the gel. This disclosure also describes a corneal implant prepared by any embodiment of the general method described herein..
03/13/14
20140074088
Circular thermal capsulotomy tool and system
A system and tool for performing a capsulotomy procedure. The system includes a capsulotomy and movement control unit providing electrical current and movement control, and a capsulotomy tool, and an extendable-retractable burning element coupled to the tool, and a slidable shaping element.
03/13/14
20140073676
Bicyclic compound and use thereof for medical purposes
Since a compound represented by the general formula (i) (wherein definition of each group is as described in the specification), a salt thereof, a solvate thereof, or a prodrug thereof has strong and sustaining intraocular pressure lowering activity and, further, has no side effect on eyes such as ocular stimulating property (hyperemia, corneal clouding etc.), aqueous humor protein rise etc., it has high safety, and can be an excellent agent for preventing and/or treating glaucoma etc.. .
03/13/14
20140072601
Transport of cells in hydrogels
The present invention relates to hydrogels which may be used to encapsulate or entrap live cells. The invention further relates to methods for transporting live cells which are encapsulated or entrapped within hydrogels from a first location to a second location.
03/06/14
20140066835
Systems and methods for corneal cross-linking with pulsed light
Systems and methods for treating an eye select locations for making incisions in areas of the cornea according to astigmatic keratotomy or radial keratotomy, make incisions in the selected areas of the cornea, apply a cross-linking agent to the selected areas of the cornea, and deliver photoactivating light from a light source to the selected areas of the cornea to initiate cross-linking activity in the selected areas of the cornea.. .
03/06/14
20140065639
Method of analyzing image of cell in laminated structure and method of evaluating laminated structure for corneal transplantation
A method of analyzing an image of a cell in a laminated structure may include the steps of: (a) fluorescently labeling a cell nucleus in the laminated structure having at least one cell layer and one or more other types of biomolecules; (b) acquiring a plurality of planar tomographic fluorescent labeled images in different height directions from the laminated structure for each type of fluorescently labeled biomolecules after the step (a); (c) superimposing a planar tomographic fluorescent labeled image group acquired in the step (b) to construct a three-dimensional tomographic image; (d) dividing the three-dimensional tomographic image constructed in the step (c) into one or two or more cell regions; (e) producing one planar stacked image for each divided cell region after the step (d); and (f) performing image analysis on each planar stacked image produced in the step (e) to analyze cells in the laminated structure.. .
02/27/14
20140058424
Novel microfabricated instruments and methods to treat recurrent corneal erosions
In one embodiment, the present invention provides a device and method for treating recurrent corneal erosion. In one embodiment, the method includes the steps of contacting an epithelium layer of a cornea with an array of glass micro-rods including a plurality of sharp features having a length that penetrates a bowman's layer of the eye, wherein the plurality of sharp features of the array of glass micro-rods produces a plurality of punctures in the bowman's layer of the eye that are of micro-scale or less.
02/27/14
20140057975
Reduced central corneal thickening by use of hydrophilic ester prodrugs of beta-chlorocyclopentanes
Compositions and methods for treating glaucoma are provided. In particular hydrophilic ester prodrugs and their use to reduce central corneal thickening is provided..
02/27/14
20140055342
Gaze detection apparatus and gaze detection method
A gaze detection apparatus includes: a first imaging unit which has a first angle of view and generates a first image; a second imaging unit which has a second angle of view narrower than the first angle of view, and generates a second image; a face detection unit which detects from the first image a face region; a coordinate conversion unit which identifies on the second image a first region corresponding to the face region or to an eye peripheral region containing the user's eye; a purkinje image detection unit which detects a corneal reflection image of a light source and the center of the user's pupil from within an eye region, identified based on the first region; and a gaze detection unit which detects the user's gaze direction or gaze position based on a positional relationship between the center of the pupil and the corneal reflection image.. .
02/20/14
20140052140
Positioning device for eye surgery and procedures
The invention provides a positioning device for use in an examination, procedure or surgery of the eye. The positioning device includes an incurvate body with an upper peripheral edge having a first arc length, a lower peripheral edge having a second arc length, and a curved lateral portion therebetween.


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Corneal topics: Endothelial, Ophthalmic, Instruments, Anterior Chamber, Coordinates, Tracking System, Endothelial Cell, Intraocular, Ocular Lens, Intraocular Lens, Ophthalmic Formulation, Parenteral, Mitochondrial, Antioxidants, Antioxidant

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