|| List of recent Corn-related patents
The invention relates to a medical device, including interchangeable parts thereof, for performing corneal cell freezing wherein said device comprises an elongate member having a flow line system through which a cryogenic fluid flows to cool a cryoprobe tip which tip is fixed and comprises a concave epithelial surface contact member.. .
|Eyesight correction apparatus and method for controlling same|
The eyesight correction apparatus according to the present invention comprises: a cutting unit for cutting out a portion of the cornea such that a stromal bed and a flap are arranged; an image processing unit for collecting, in images, the state between the flap which is located on the stromal bed and processing the images; a beam generating unit for generating a joining beam for interconnecting between the flap and a cut area of the cornea on the basis of the image signal processed by the image processing unit; a beam delivery unit for guiding the joining beam along the cut area between the flap and the cornea; and a control unit for controlling an operation of the beam delivery unit such that the joining beam can be radiated along the cut area between the flap and the cornea on the basis of the image signal.. .
|Methods and systems for tracking a torsional orientation and position of an eye|
Methods and systems for tracking a position and torsional orientation of a patient's eye. In one embodiment, the present invention provides methods and software for registering a first image of an eye with a second image of an eye.
In a non-contact tonometer, puffing of air unnecessary for measurement of an eye to be inspected after driving of a solenoid is stopped is suppressed. In the non-contact tonometer including a corneal shape change unit configured to change the shape of the cornea by pressurizing and supplying a gas in a cylinder by a piston, and an eye pressure measuring unit configured to measure the eye pressure from the state of the shape change of the cornea, an opening portion configured to be formed in the outer wall of the cylinder and decide the internal volume of the cylinder when pressurizing the gas, and a pressurized gas volume change unit configured to change a position where the opening portion can connect the inside of the cylinder with the outside, and change the internal volume of the cylinder when pressurizing the gas..
|Non-contact tonometer, control method of the same, and program|
An excessive amount of pressurized air is inhibited from being blown to an eye of a patient during measurement of a corneal shape deformation amount. In a non-contact tonometer having a piston, a driving unit to drive the piston, a fluid election unit to blow air pressurized by driving the piston toward a cornea of an eye to be inspected, and an interocular pressure measuring unit to detect a deformed state of the cornea and measure an interocular pressure, there are provided a piston displacement restricting unit that restricts a displacement amount when the piston pressurizes the air, and a changing unit to change the displacement amount to be restricted by the piston displacement restricting unit..
|Apparatus for electrodermal activity measurement with current compensation|
An apparatus for measuring electrodermal activity can include a first electrode in contact with a first portion and a second electrode in contact with a second portion of a stratum corneum, and in electronic communication with the second electrode through the stratum corneum. A processing module is electrically coupled to the first electrode and the second electrode and is operable to (a) bias the first electrode at a first voltage v+ and the second electrode at a second voltage v− (b) measure a current flowing between the first electrode and the second electrode, the current corresponding to the conductance of the stratum corneum, (c) subtract a compensation current from the measured current (d) measure a resulting current producing an amplified output voltage (e) measure a conductance of the stratum corneum, and (f) adjust at least one of the first voltage, the second voltage and the compensation current to desaturate the output voltage..
|Method for producing corneal endothelial cell|
The invention provides a method of efficiently producing corneal endothelial cells, particularly from corneal stroma or ips cell-derived neural crest stem cells, a method of producing corneal endothelial cells stably in a large amount by inducing more efficient differentiation of stem cells into corneal endothelial cells, and a medicament containing corneal endothelial cells. The method of inducing differentiation of stem cells into corneal endothelial cells includes a step of culturing the stem cells in a differentiation induction medium containing a gsk3 inhibitor (preferably a gsk3β inhibitor) and retinoic acid, with the differentiation induction medium preferably further containing one or more of tgfb2, insulin, a rock inhibitor, and the like..
|Microfluidic chips for acquiring sperms with high motility, productions and applications thereof|
This invention relates to microfluidic chips for and their applications in acquiring sperms with high velocity and/or motility. The microfluidic chip comprises an inlet region, a first flow channel, a divergent channel, an optional block structure with rounded corners and one or more outlet region(s).
|Endothelial cell culture|
The disclosure relates to cell culture vessels comprising fabricated cell culture surfaces providing means for efficient corneal endothelial cell growth and the use of the cultured cells in the repair of corneal tissue damage.. .
|Ophthalmic device, control method, and non-transitory computer readable medium|
Provisioned is a selecting unit configured to select a bright spot image corresponding to a reflected light beam reflected by the cornea of the subject eye from among a plurality of bright spot images on the basis of a positional relationship between a first bright spot image formed from a plurality of bright spot images corresponding to a first light beam in a first direction and a second bright spot image corresponding to a second light beam in a second direction different than the first direction, and a calculating unit configured to calculate a state of alignment between the subject eye and a measuring unit using the bright spot image selected from the first bright spot images.. .
An ophthalmic apparatus for guiding positioning an intraocular lens for astigmatism correction, includes: an obtaining unit for obtaining an anterior segment image of a patient's eye and an astigmatic axis of a patient's cornea; a feature point designating unit for defining a feature point of an iris or a sclera on the anterior segment image; and a display control unit for superimposing and displaying a gauge image that models a cornea gauge and an axis that represents the astigmatic axis of the cornea on the anterior segment image.. .
An intraocular lens in which deterioration in contrast is suppressed even when the optical axis of the intraocular lens is decentred from the optical axis of the eyeball when the intraocular lens is inserted into the eye while the advantage of a conventional aberration reduction type intraocular lens that the image is seen clearly is sustained by employing such a power distribution as respectively having at least one positive power deviation region (e1) having a power larger than that represented by the reference power distribution and at least one negative power deviation region (e2) having a power smaller than that represented by the reference power distribution in the central region of the intraocular lens assuming that a power distribution being set to cancel the spherical aberration of cornea when the intraocular lens is inserted into the eye is the reference power distribution.. .
|Yeast expressing saccharolytic enzymes for consolidated bioprocessing using starch and cellulose|
The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity.
|Contact lens for vitreoretinal surgery|
A contact lens assembly has a central lens and a circumscribing flange, the lens having an eye contact surface shaped generally to a radius of curvature of a cornea of an eye. The flange comprises a sterile sponge-like liquid absorbent flexible material having a central aperture for fitting snugly about an outer circumference of the lens and extending radially outward therefrom.
|Ophthalmologic apparatus, method for controlling ophthalmologic apparatus, and program|
An ophthalmologic apparatus is configured to determine a direction in which a target that is used to adjust a working distance comes into focus based on an influence of astigmatism contained in a cornea reflection image of an eye to be examined.. .
|Ophthalmic observation apparatus and method of using the same|
An ophthalmic observation apparatus includes an illumination light supplier which supplies illumination light, of substantially parallel light rays, toward an examinee's eye including an eyeground and an anterior chamber angle, an imager which captures an image of the eye which is illuminated by the illumination light, a rotary driver which rotates the illumination light supplier and the imager about a specified center, a cornea curvature measurer which measures a curvature of a cornea of the examinee's eye, and a controller which sets a curvature center of the cornea as the specified center based on the measured curvature of the cornea. The controller drives the rotary driver to rotate the illumination light supplier and the imager about the specified rotational center and controls the imager to capture an image of the eyeground and the anterior chamber angle illuminated by the illumination light..
|Exfoliating head for a personal care appliance|
Exfoliating heads with an abrasive surface are disclosed for use with a personal care appliance. The personal care appliance is configured to oscillate the exfoliating head to provide improved smoothing and exfoliation of a subject's epidermis with or without the antecedent application of skin care formula.
|Solar collector comprising an opaque cover|
A solar collector has an opaque cover heated by solar energy. Heat flows from the opaque cover by conduction, convection, and infrared emittance across a gap within an at least substantially airtight enclosure to an absorber containing a working fluid.
|Diapers, diaper wipes and diaper pads with active ingredients integrated therein|
A diaper, diaper sheet insert and/or a diaper wipe sheet with active ingredients integrated therein, including ointments for treating diaper rash, baby oils and lotions for treating dry skin, and/or powder treatments for absorbing moisture, including baby powder, corn starch powders and the like. In a first embodiment, the invention provides a diaper having active ingredients integrated therein comprising a skin-contact surface, at least one inner absorption layer, an outer most layer, and a barrier wall having an active ingredients segment and preventing contact of the active ingredients with the diaper's skin-contact surface.
|Cross-linking composition delivered by iontophoresis, useful for the treatment of keratoconus|
An improved formulation of an ophthalmic composition contains riboflavin, as cross-linking agent of corneal collagen, administered by corneal iontophoresis, able to guarantee an increased capacity of permeation of riboflavin of the corneal stroma and therefore greater therapeutic efficacy in the treatment of keratoconus.. .
|Indices for management of dry eye syndrome, corneal ectasia, keratoplasty graft rejection and failure and fuchs' dystrophy|
Improved indices for the diagnosis and evaluation of conditions affecting the eye. Specifically, the indices include an enhanced epithelial irregularity factor (eeif) for the diagnosis and evaluation of conditions such as dry eye syndrome (des), bowman's ectasia index (bei), including enhanced bei (ebei) and bei-max, and bowman's relative thinning (brt) index for the diagnosis and evaluation of ectatic conditions such as keratoconus, pellucid marginal degeneration, post-refractive surgery ectasia, and keratoglobus, and descemet's membrane thickening index (dmt), descemet's rejection index (dri), and descemet's membrane irregularity factor (dif) for the diagnosis and evaluation of conditions such as keratoplasty rejection and failure and fuchs' dystrophy.
|Apparatus for optometric self-examination, management server and contact lens selection system|
An object of the present invention is to provide an apparatus for optometric self-examination, a management server and a contact lens selection system using the same that are readily available to a new user and additionally shorten a time period required by an eye care practitioner for prescription or, even if no eye care practitioner's prescription is provided, allow for selection of a contact lens preferred for the user. The apparatus for optometric self-examination includes an optometric data acquisition unit for determining at least a part of a shape of a cornea of a user in response to an operation by the user and acquiring optometric data, based on the shape of the cornea, and a contact lens data display unit for displaying a result of selection of a contact lens suited for the optometric data, based on the optometric data and the shape data of contact lenses..
|Skin preparation device and biopotential sensor|
The skin preparation device and sensor of the present invention include an array of rigid tines. The tines serve to “self-prepare” the skin at each electrode site.
|Hydrolysis-resistant silicone compounds|
In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds.
|Macroinitiator containing hydrophobic segment|
The present invention relates to macroinitiators comprising at least one hydrophobic segments in a molecule, wherein a molecular weight of the hydrophobic segment is 300 to 1800. The present invention further relates to block copolymers, wetting agent and polymeric materials having the block copolymers of the present invention associated with, which is suitable for medical devices, particularly for ophthalmic devices, including contact lenses, ophthalmic lenses, punctal plugs and artificial corneas..
|Method and system for compact optical coherence tomography|
The tunable filter placed in front of the detector to make the interferometer more sensitive and accurate for reading various samples for diagnosis. Optical coherence tomography (oct) system and apparatus of this instant application is very useful for diagnosis and management of ophthalmic diseases such as retinal diseases and glaucoma etc.
|Corneal imaging device|
A corneal imaging device provided with an optical system for photographing a corneal portion of an eye, the optical system including an illumination optical system configured to irradiate illumination light toward a cornea and a light receiving optical system placed in a position inclined with respect to an optical axis of the illumination optical system configured to receive reflection light from the cornea by a photodetector, wherein the corneal imaging device includes light-limiting means provided in an optical path of the optical system for photographing the corneal portion of the eye and configured to limit light asymmetrically with respect to an optical axis.. .
|Device to store and inject corneal graft|
Devices and methods for storing and injecting a corneal tissue graft are disclosed herein. In one embodiment, an apparatus includes a tissue container and an adaptor configured to be coupled to the tissue container.
|Eye surgery refraction correction|
A planning device produces control data for a treatment device for eye surgery which produces at least one cutting surface in a cornea of the eye using a laser device. The planning device includes a calculation module for establishing a cornea cutting surface.
|Treatment device for the surgical correction of defective vision of an eye, method for producing control data therefor, and method for the surgical correction of defective vision of an eye|
A treatment device for the surgical correction of defective vision in an eye. The device includes a laser apparatus controlled by a controller.
|Angle measurement system including magnet with substantially square face for through-shaft applications|
To make the magnetic field lines straighter and more parallel to one another, the present disclosure makes use of substantially square magnets with through-holes therein. It will be appreciated that “substantially square” magnets include magnets that are precisely square as well as magnets that are approximately square (e.g., have rounded corners or other small deviations from being square.) by providing straighter and more parallel magnetic field lines, such substantially square magnets tend to enable greater precision and accuracy when rotational angles of a shaft are measured..
|Micro-nano tools with changeable tips for micro-nano manipulation|
The present invention relates to modular system for micro-nano manipulation of samples. The modular system of the present invention comprises changeable tool tips which may be provided in an array, and a tool body.
|Image display apparatus and control method thereof|
The present disclosure relates to an image display apparatus, and more particularly, an image display apparatus capable of displaying screen information. The image display apparatus includes a display configured to display screen information, an interface configured to receive an input signal with respect to the display, and a controller configured to display a menu item for controlling the screen information, wherein the display outputs the screen information on an inner region of rounded corners of the display, and wherein the controller decides a shape of the menu item to be displayed on a point where the input signal has been received, in response to the reception of the input signal..
|Crystalline polymeric compositions for ophthalmic devices|
Ophthalmic devices suitable for implantation into the eye through small incisions or insertion into an existing orifice are disclosed. These devices are made from a composition comprising crystalline or semi-crystalline polymeric materials which have a glass transition temperature (tg) of from about −100° c.
|In situ adjustable optical mask|
Implantable corneal and intraocular implants such as a mask are provided. The mask can improve the vision of a patient, such as by being configured to increase the depth of focus of an eye of a patient.
|Treatments of extracellular matrices of the eye|
System and methods for a corrective eye procedure include at least one application device configured to be positioned at a selected area of an eye (e.g., equatorial sclera, posterior sclera, cornea, etc.). The at least one device includes at least one channel and at least one illumination guide.
|Apparatus, system, and method for providing an implantable ring for altering a shape of the cornea|
An apparatus, system and method for constricting a cornea of a human eye are disclosed. A control device external to the subject eye, such as an induction generator, may be configured to create a stimulus, such as a magnetic field, for an implanted ring that, when stimulated, may change the curvature, and thus the dioptric power, of the eye, thereby approximating natural accommodation..
|Toric axis marker|
A toric axis marker has a handle, a coaxial tip, a head upon the tip, a dial axially above the head, and a marker head with two blades connecting to the dial. The dial and blades rotate simultaneously and concentrically upon the head.
|Systems and devices for shaping human cornea and methods of use thereof|
In some embodiments, the instant invention provides for a system for shaping a human cornea of an eye that includes at least the following components: a sapphire applanation window/suction ring (sawsr) system, where the sawsr system includes a sapphire applanation window/suction ring (sawsr), a conical holder, an illuminator, and a temperature control, where the sawsr system is configured to: (i) be positioned on the eye, (ii) applanate the human cornea of the eye, (iii) generate and position a centration aid, and (iv) maintain temperature control; an optical delivery system, where the optical delivery system includes: (i) a laser, (ii) a fiber delivery holder, and (iii) a laser control subsystem, where the laser control subsystem is configured to display a user interface to: 1) control a power and a temporal waveform of each of the beamlets of light, and 2) irradiate the human cornea of the eye.. .
|Systems and methods for providing anatomical flap centration for an ophthalmic laser treatment system|
Embodiments of this invention relate to systems and methods for providing anatomical flap centration for an ophthalmic laser treatment system. In one embodiment, the laser surgery system, having an imaging system and a suction ring coupled with a patient interface, captures a digital image of a subject's eye and identifies an optimum treatment placement of the corneal flap using anatomical markers as reference points..
|Systems and methods for laser correction of astigmatism incident with lens replacement surgery|
A nomogram, a method for determining how to cut a cornea to produce a particular vision correction, and a system and method for determining how to make a vision correction when a precision cutting tool is being used as opposed to the performance of hand cuts. In a further embodiment, measurement of astigmatism to be corrected, calculation of the nomogram, and the actual cutting are mostly or completely automated eliminating human error from the system..
|Hybrid ophthalmic interface apparatus|
Apparatus and methods are provided for interfacing an ophthalmic surgical laser with an eye using a patient interface (pi). The pi may include a closed, fluid-filled bladder having fiducials that contacts and deforms to the eye.
|Wireless intraocular pressure monitoring device, and detecting module thereof|
A wireless intraocular pressure monitoring device includes reflecting and detecting modules. The reflecting module includes a soft contact lens having a curvature corresponding to that of a cornea while worn.
|Collagen-based ophthalmic interface for laser ophthalmic surgery|
Embodiments of a collagen-based ophthalmic interface for reducing patient eye movement are disclosed. In one embodiment, an ophthalmic interface serving as a partial barrier between a patient's eye and a surgical laser system includes an annular-shaped collagen-based shield configured to overlay the anterior surface of the eye.
|Magnetic juggling apparatus|
At least one embodiment of the invention describes a magnetic juggling apparatus that includes at least a first juggling structure and a second juggling structure, wherein each juggling structure has a front face, a back face, four or more non-magnetic sides, four or more rounded corners between each of the four or more non-magnetic sides respectively, a hollow opening and four or more magnetic sources of an even number. The magnetic juggling apparatus allows a user to manipulate the first juggling structure or the second juggling structure, or the first juggling structure and the second juggling structure simultaneously to re-arrange a first magnetic pattern or a second magnetic pattern through acceptance of at least one action from the group consisting of a rotational action, a pushing action, a pulling action and a sliding action..
|Treatment of ophthalmic conditions|
Ophthalmic conditions such as presbyopia, myopia, and astigmatism can be corrected by the use of a molding contact lens in combination with a pharmaceutical composition suitable for delivery to the eye. The molding contact lenses are preferably commercially available and are not specifically designed for orthokeratology.
|System and method for ocular aberrometry and topography using plenoptic imaging|
Improved systems and methods for ocular topography and using a plenoptic detector are provided. For example, a multifunction ocular topography and aberrometry system can comprise a first set of light sources, a second light source, a plenoptic detector and a processing system coupled to the plenoptic detector.
|System and method for corneal pachymetry using plenoptic imaging|
Embodiments described herein provide improved systems and methods for corneal pachymetry. These systems and methods can be used to improve the accuracy of corneal measurements that are used for a wide variety of different ophthalmic procedures.
|Portable fundus camera|
A portable hand-held ocular fundus camera system for imaging the fundus of the eye is disclosed. The camera system is comprised of a camera housing, one or more groups of lens in an internal cavity of the housing, a front group of lenses at the front end of the internal cavity, a contact member to contact at least a portion of the cornea, a light source configured to direct light from locations inside the camera through an annulus near the periphery of the front lens group, so that the light enters the eye through an annulus at the periphery of the pupil of the eye during contact with the cornea.
|High dynamic range capacitive sensing|
Improving fingerprint image measurement despite damage to the stratum corneum. Determining whether a fingerprint image is adequate for matching with a database.