|| List of recent Corn-related patents
| Process for preparing objects made of biocompatible hydrogel for uses thereof in the medical field, and more particularly in ophthalmology|
The present invention also relates to the objects made of biocompatible hydrogel resulting from this process such as, for example, intracorneal lenses (or lenticules) implantable in the cornea or any other implants usable in ophthalmology.. .
| Sodium channel blocker delivery system with scleral lens|
A scleral lens is provided with a sodium channel blocker or a sodium channel modulator disposed in the pre-corneal tear film between the scleral lens and the cornea. This system can be used to deliver sodium channel blockers or a sodium channel modulators not currently used because of poor bioavailability.
Boston Foundation For Sight
| System for inserting an intracorneal lens|
The present invention relates to a system for inserting an intracorneal lens into an eye, comprising an imaging unit (a) for generating an image of the eye, an image processor (4) for generating a virtual image of the eye with the desired position of a pocket to be cut into the cornea, a laser unit (b) for cutting a pocket into the cornea of the eye, with a control device (13) with which, on the basis of the virtual image of the eye generated by the image processor (4), the pocket can be generated in the cornea of the eye by the laser, an insertion unit (c) for inserting an intracorneal lens into the pocket in the cornea with an optical device (11), wherein the insertion of the intracorneal lens with the optical device can be controlled on the basis of the generated virtual image of the eye, by superposing the virtual image of the eye with the real image of the eye visible through the optical device.. .
| Power management in an eye-tracking system|
An imaging device adapted to provide eye-tracking data by imaging at least one eye of a viewer, wherein: the imaging device is switchable between at least an active mode and a ready mode; the imaging device is configured to use active eye illumination in the active mode, which enables tracking of a corneal reflection; and the imaging device is configured, in the ready mode, to reduce an illumination intensity from a value the illumination intensity has in the active mode, and to provide eye-tracking data which include eye position but not eye orientation.. .
Tobii Technology Ab
|Marking lenticules for refractive correction|
In certain embodiments, marking a lenticule includes controlling a focus of pulsed laser radiation having ultrashort pulses. A lenticule marking is created in a cornea of an eye with the pulsed laser radiation to mark the lenticule.
|Antigens and vaccines directed against human enteroviruses|
The instant invention provides materials and methods for producing immunologically active antigens derived from members of the picornaviridae virus family. The picornavirus antigens of the invention may be in a form for use as a vaccine administered to a subject in a therapeutic treatment or for the prevention of a picornavirus infection.
Sentinext Therapeutics Sdn Bhd
|Ophthalmological vehicle system for drugs, ophthalmological kit and also use of an ophthalmological composition|
The present invention relates to an ophthalmological vehicle system for the permeation and/or for the active substance transport of ophthalmological active substances through the cornea and/or the sclera of the eye of mammals. This vehicle system assists the transport of the active substances through the cornea and/or the sclerotic tissue of the eye.
F. Holzer Gmbh
|Ophthalmic compositions comprising povidone-iodine|
A topical ophthalmic composition comprised of povidone-iodine 0.01% to 10.0% combined with a steroid or non-steroidal anti-inflammatory drug. This solution is useful in the treatment of active infections of at least one tissue of the eye (e.g., conjunctiva and cornea) from bacterial, mycobacterial, viral, fungal, or amoebic causes, as well as treatment to prevent such infections in appropriate clinical settings (e.g.
Cls Pharmaceuticals, Inc.
|Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography|
Ocular surface interferometry (osi) devices, systems, and methods are disclosed for measuring a tear film layer thickness (tflt) of the ocular tear film, including the lipid layer thickness (llt) and/or the aqueous layer thickness (alt). The tflt can be used to diagnose dry eye syndrome (des).
|Contact lenses having a reinforcing scaffold|
Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include an inner optic portion having a scaffold between an anterior portion and a posterior portion.
Visual display with illuminators for gaze tracking
A visual display includes hidden reference illuminators adapted to emit invisible light for generating corneo-scleral reflections on an eye watching a screen surface of the display. The tracking of such reflections and the pupil center provides input to gaze tracking.
Tobii Technology Ab
The present invention relates to an intracorneal lens (1), comprising a circular main body having a convex front surface and a convex rear surface, characterized in that the convex front surface has a single uniform radius of curvature (rcv) and the concave rear surface has a radius of curvature (rcci). The radius of curvature (rcci) of the concave rear surface is greater than the average radius of the cornea by 0.1 mm to 2 mm, preferably 0.2 to 1.5 mm, in particular preferably 0.5 to 1 mm the present invention further relates to a kit, comprising a storage unit (15) and a pre-load unit (p) inside the storage unit (15).
Corneal vitrification, methods and devices to produce corneal vitrification and methods of use thereof
The invention includes: a new composition of matter (a composite comprising a naturally occurring in vivo cornea in an in situ eye together with at least one volume of vitrified non-naturally occurring corneal stromal tissue formed within the naturally occurring corneal stromal tissue) wherein the vitrified tissue is modified in structure and properties from its naturally occurring condition into a non-naturally occurring glass-like condition with modifications including but not limited to increased eletastic modulus; methods for producing and using the new composition of matter for modifying cortical structure and properties, including but not limited to corneal optical aberrations; wound closure adhesion and transplant adhesion; and a photovitrification system for producing the new composition of matter comprising at least one photon source with controllable treatment parameters. A reverse template can be added to corneal vitrification systems to increase vitrification and modifications of structure and properties..
Ocular insert apparatus and methods
A comfortable insert comprises a retention structure sized for placement under the eyelids and along at least a portion of conjunctival sac of the upper and lower lids of the eye. The retention structure resists deflection when placed in the conjunctival sac of the eye and to guide the insert along the sac when the eye moves.
Sustained release delivery of one or more agents
The lacrimal implant delivery systems and methods described herein provide for controlled release of a therapeutic agent for the treatment of disease, including the treatment of glaucoma, ocular hypertension, or elevated intraocular pressure with latanoprost or other anti-glaucoma agents. Treatment of disease, including glaucoma, ocular hypertension, or elevated intraocular pressure with latanoprost or other anti-glaucoma agent in conjunction with penetration enhancer, such as benzalkonium chloride, and/or artificial tears is also provided.
Pterygium animal model using human pterygial epithelial cells
Provided is a pterygium animal model produced by injecting human-derived pterygial epithelial cells that are isolated and cultured in vitro. The animal model has characteristics similar to those of pterygium, which are observed only in humans, wherein such characteristics are caused in such a way that pterygial epithelial cells are isolated from human pterygium corneal tissues and cultured, the cultured pterygial epithelial cells are sub-cultured, and human-derived pterygial epithelial cells of which identify is confirmed are injected into the nasal subconjunctival space of mice.
Systems and methods for mapping the ocular surface
Examples of methods and apparatus for an accurate measurement of the anterior surface of the eye including the corneal and scleral regions are disclosed. The measurements provide a three-dimensional map of the surface which can be used for a variety of ophthalmic and optometric applications from astigmatism and keratoconus diagnostics to scleral lens fitting..
Process and determining optical aberrations of an eye
A process and an apparatus are proposed for determining optical aberrations of an eye with its optical system including the cornea and the lens. The process includes the reconstructing of wavefront aberrations of the eye as a deviation of the wavefront, determined by the optical system of the eye with a process of aberrometry, with respect to an ideal planar wavefront generated by an aberration-free eye model.
Model eye producing a speckle pattern having a reduced bright-to-dark ratio for use with optical measurement system for cataract diagnostics
A system includes a model eye and an optical measurement instrument, which includes: a corneal topography subsystem; a wavefront sensor subsystem; and an eye structure imaging subsystem. The subsystems may have a common fixation axis, and be operatively coupled to each other via a controller.
Methods for machining sharp internal pocket corners with rotating cutting tools
Methods of machining a housing of a portable computing device are provided. A cutting tool may be moved perpendicularly to a rotational axis during each rotation thereof to machine a substrate and define pockets and holes including substantially non-rounded corners.
Medical device, assembly and creating a channel in soft tissue
The present disclosure provides a device, an assembly comprising the device and a method making use of same, the device comprising an elongated member extending between a first end and a second end, and a segment proximal to the second end extending along a longitudinal axis x, said segment comprises at least one depression axially extending along at least a portion of said segment and an external surface having a circumference c; and one or more blades with a cutting edge peripheral to c and the one or more blades extending along at least part of said segment; the first end comprising an engagement element for engagement with a grip unit comprising a rotor to cause rotation of said device about said axis upon actuation of the rotor and the second end comprising a tissue piercing tip. The device, assembly and method are useful in creating a channel in a biological soft tissue, such as a drainage channel in the sclero-corneal junction area of the eye.
Tel Hashomer Medical Research Infrastructure And Services Ltd.
Conjunctival cover and methods therefor
A conjunctival cover including an annular generally curved shell having a conjunctival portion structured to conform to and overly at least part of the conjunctiva of an eye. The annular generally partially spherical shell defines a generally central opening.
Ocular cross-linking sealing corneal wounds
Wounds in the eye following surgery or injury are sealed by soaking the area with a riboflavin solution containing iodide ion and irradiating the wound area with uva radiation in a selected wavelength range for a selected time period to promote cross-linking of tissue between opposite surfaces of the wound or between the incised wound surfaces and a graft or implant.. .
Cxl Ophthalmics, Llc
Skin screw electrodes
Electrodes providing excellent recording and physical stability. Electrodes are disclosed that may include a plurality of small teeth that possess a novel design shape and orientation.
University Of Pittsburgh - Of The Commonwealth System Of Higher Education
A composition that is useful in a skin function improving agent includes at least two of the following: vitamin k, a sapogenol, and a collagen hydrolysate. This composition can be used in a skin function improving agent and is particularly useful in a skin function improving agent for inhibiting transdermal moisture loss and/or for retaining the moisture in the stratum corneum..
J-oil Mills, Inc.
Contact lens and prevention of myopia progression
A method of slowing the progression of myopia in a person, comprises applying to the eye of the person a contact lens or lenses to mould the surface of the cornea. On removal of the lens, the shape of the corneal surface includes a vision correction area for correcting the myopic vision of the person, and a myopic defocus area having a more positive power and located within the pupil area, to simultaneously present a controlled myopic defocus to the retina both when viewing in the distance and also when viewing at near, without the lens in place on the cornea.
Delivering ocular implants into the eye
A method of deploying an ocular implant into schlemm's canal of an eye. The method includes the steps of inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula having a distal opening extending from the distal end and through a side wall; placing the distal opening of the cannula into fluid communication with schlemm's canal; advancing the ocular implant distally through the cannula with a delivery tool engaged with the ocular implant, a proximal portion of the ocular implant engaging the delivery tool proximal to a distal portion of the delivery tool; and disengaging the ocular implant and the delivery tool when the proximal portion of the ocular implant reaches the cannula distal opening.
Technique for controlling a corneal ablation laser
A device for optical coherence tomography comprises a light generator, a dispersive medium, an optical coupler and a detector. The light generator is adapted to generate input pulses of coherent light, each input pulse having an input pulse width.
Method for characterizing a cornea and obtaining an ophthalmic lens
A system and method for determining the shape of a cornea of an eye illuminates at least one of the interior surface, the posterior surface, and the interior region of the eye with infrared light of a wavelength that can generate fluorescent light from the portion of the cornea illuminated. The generated fluorescent light is then detected.
Perfect Ip, Llc
Bicyclic compound and use thereof for medical purposes
Since a compound represented by the general formula (i) (wherein definition of each group is as described in the specification), a salt thereof, a solvate thereof, or a prodrug thereof has strong and sustaining intraocular pressure lowering activity and, further, has no side effect on eyes such as ocular stimulating property (hyperemia, corneal clouding etc.), aqueous humor protein rise etc., it has high safety, and can be an excellent agent for preventing and/or treating glaucoma etc.. .
Ono Pharmaceutical Co., Ltd.
A solid cosmetic composition includes (i) corn starch in an amount of from about 20% to about 40%; (ii) bulking agent in an amount of from about 20% to about 50%; (iii) surfactant in an amount of from about 5% to about 30%; and (iv) glycerine in an amount of from about 15% to about 30%, present in an amount by weight of the total composition.. .
Cosmetic Warriors Limited
Semiconductor device and fabricating the same
A semiconductor device includes a first device isolation pattern defining a first active region, a second device isolation pattern defining a second active region, a first gate disposed on the first active region, the first gate including a gate insulating pattern of a first thickness and a second gate disposed on the second active region, the second gate including a gate insulating pattern of a second thickness greater than the first thickness. A top surface of the first device isolation pattern is curved down toward the first active region such that the first active region has an upper portion protruded from the top surface and rounded corners..
Samsung Electronics Co., Ltd.
Laser corneal flap cutting system and associated methods
A method for performing wavefront-guided laser surgery on a cornea includes the step of calculating a corneal flap configuration based upon collected anatomical information on an eye and wavefront data on a cornea of the eye. Such data may be collected by, for example, an aberrometer, although this is not intended as a limitation.
Alcon Refractivehorizons, Inc.
Methods for requesting and checking results of diagnostic tests for avellino corneal dystrophy
A portable electronic device with a touch-sensitive display launches a software application configured for requesting a diagnostic test for avellino corneal dystrophy and checking a result of the diagnostic test for avellino corneal dystrophy. The device logs in to the software application.
Avellino Co., Ltd
Systems and methods for applying and monitoring eye therapy
Devices and approaches for activating cross-linking within corneal tissue to stabilize and strengthen the corneal tissue following an eye therapy treatment. A feedback system is provided to acquire measurements and pass feedback information to a controller.
Glaucoma drainage shunts and methods use
A method of treating glaucoma in an eye utilizing an implanted shunt having an elastomeric plate and a non-valved elastomeric drainage tube. The plate is positioned over a sclera of the eye with an outflow end of the elastomeric drainage tube open to an outer surface of the plate.
Abbott Medical Optics Inc.
Multifocal ophthalmic lens
A method of designing a multifocal ophthalmic lens with one base focus and at least one additional focus, capable of reducing aberrations of the eye for at least one of the foci after its implantation, comprising the steps of: (i) characterizing at least one corneal surface as a mathematical model; (ii) calculating the resulting aberrations of said corneal surface(s) by employing said mathematical model; (iii) modelling the multifocal ophthalmic lens such that a wavefront arriving from an optical system comprising said lens and said at least one corneal surface obtains reduced aberrations for at least one of the foci. There is also disclosed a method of selecting a multifocal intraocular lens, a method of designing a multifocal ophthalmic lens based on corneal data from a group of patients, and a multifocal ophthalmic lens..
Amo Groningen B.v.
Buffered ophthalmic compositions and methods of use thereof
The present disclosure provides a buffered ophthalmic composition for formulation of topically administrable suspensions useful for treating eye disorders by promoting wound healing, delivery of pharmaceutically active agents, and lubricating the eye. In particular the ophthalmic composition includes a buffer solution compatible with application to a mammalian eye, wherein the buffer provides increased mechanism of action of pharmaceutically active agents as well as therapeutic qualities.
Arava Bio-tech Ltd.
Method for evaluating cosmetic
It is an object of the invention to provide a method for evaluating cosmetics that allows development of cosmetics that can contribute to beautiful healthy skin. The object is achieved by a method of evaluating improvement in skin by an applied cosmetic, using as the index the change in stratum corneum thickness during the process of moistening and drying..
Shiseido Company, Ltd.
Primers for diagnosing avellino corneal dystrophy
The present invention relates to a real-time pcr primer pair and probe for diagnosing avellino corneal dystrophy, and more particularly to a real-time pcr primer pair and probe for diagnosing avellino corneal dystrophy, which can accurately diagnose the presence or absence of a mutation in exon 4 of bigh3 gene, which is responsible for avellino corneal dystrophy. The use of the primer pair and probe according to the invention can diagnose avellino corneal dystrophy in a more rapid and accurate manner than a conventional method that uses a dna chip or pcr..
Avellino Co., Ltd.
Determination of the effective lens position of an intraocular lens using aphakic refractive power
An ophthalmic method for determining a relationship between aphakic ocular power and estimated effective lens position (elp) of an intraocular lens (iol) to be implanted in a patient's eye. The method can be used to determine an estimate of the elp of an iol given the aphakic ocular power of the patient's eye, for example, without measurement of the corneal curvature or axial length of the patient's eye.
Wavetec Vision Systems, Inc.
Silicone hydrogel lenses with water-rich surfaces
The invention is related to a hydrated silicone hydrogel contact lens having a layered structural configuration: a lower water content silicone hydrogel core (or bulk material) completely covered with a layer of a higher water content hydrogel totally or substantially free of silicone. A hydrated silicone hydrogel contact lens of the invention possesses high oxygen permeability for maintaining the corneal health and a soft, water-rich, lubricious surface for wearing comfort..