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Congestive Heart Failure

Congestive Heart Failure-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Systemic delivery of virus vectors encoding urocortin-2 and related genes to treat diabetes-related cardiac dysfunctions ...
The Regents Of The University Of California
June 29, 2017 - N°20170182129

In alternative embodiments, provided are methods for treating, ameliorating or protecting (preventing) congestive heart failure (chf) or a diabetes-related cardiac dysfunction, comprising: providing a urocortin 2-encoding and/or a urocortin 3-encoding nucleic acid, transcript or message, or gene, operatively linked to a transcriptional regulatory sequence, optionally contained in an expression vehicle or a vector such as an adeno-associated virus (aav), ...
Pulmonary artery implant apparatus and methods of use thereof
The Regents Of The University Of California
June 22, 2017 - N°20170172771

The present invention relates to an implantable apparatus and methods of use thereof for treating congestive heart failure. An apparatus of this invention may be anchored by implantation of a section of the apparatus within in a branch pulmonary artery, for example the left pulmonary artery, which then positions and anchors another section, for example a device frame section of ...
Treating dysfunctional cardiac tissue
Bioventrix, Inc.
June 08, 2017 - N°20170156865

Medical devices, systems, and methods reduce the distance between two points in tissue, often for treatment of congestive heart failure and often in a minimally invasive manner. An anchor is inserted along an insertion path through a first wall of the heart. An arm of the anchor is deployed and rotationally positioned according to a desired alignment. Application of tension ...
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Preparation of (r,r)-fenoterol and (r,r)- or (r,s)-fenoterol analogues and ...
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv
March 23, 2017 - N°20170081276

This disclosure concerns the discovery of (r,r)- and (r,s)-fenoterol analogues which are highly effective at binding β2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (r,r)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders ...
Methods for renal neuromodulation
Medtronic Ardian Luxembourg S.a.r.l.
March 23, 2017 - N°20170080230

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e. G., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment ...
Method and apparatus for performing peritoneal ultrafiltration
Triomed Ab
March 16, 2017 - N°20170072125

Method and apparatus for ultrafiltration of a patient being overhydrated due to congestive heart failure, comprising a cassette having four inlets/outlets. A patient tube is connected to a patient connector, intended to be connected to a patient line for access to a peritoneal cavity of the patient. The patient tube comprises a flow pump for addition and removal of ...
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Methods and materials for treating elevated sympathetic nerve activity conditions
Mayo Foundation For Medical Education And Research
March 09, 2017 - N°20170065327

This document provides methods and materials involved in treating hypertension (e. G., age-associated hypertension, resistant hypertension, or chronic refractory hypertension), heart failure (e. G., congestive heart failure), or kidney disease (e. G., chronic kidney disease). For example, methods and materials involved in administering one or more sympatholytic agents to a patient to identify the patient as having an elevated baseline ...
Heteroaromatic compounds and their use as dopamine d1 ligands
Mayo Foundation For Medical Education And Research
March 02, 2017 - N°20170057947

And pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating d1-mediated (or d1-associated) disorders including, e. G., schizophrenia (e. G., its cognitive and negative symptoms), cognitive impairment (e. G., cognitive impairment associated with schizophrenia, ad, pd, or pharmacotherapy therapy), adhd, ...
Prodrug of an ice inhibitor
Mayo Foundation For Medical Education And Research
January 26, 2017 - N°20170022249

Compound i is useful for treating il-1 mediated diseases such as rheumatoid arthritis, inflammatory bowel disease, crohn's disease, ulcerative colitis, inflammatory peritonitis, septic shock, pancreatitis, traumatic brain injury, organ transplant rejection, osteoarthritis, asthma, psoriasis, alzheimer's disease, myocardial infarction, congestive heart failure, huntington's disease, atherosclerosis, atopic dermatitis, leukemias and related disorders, myelodysplastic syndrome, uveitis or multiple myeloma.
Platelet rich plasma formulations
Mayo Foundation For Medical Education And Research
January 26, 2017 - N°20170020923

Compositions for platelet rich plasma (prp) and neutrophil-depleted prp are provided. Methods for treating ischemia damaged tissues by delivering a prp composition, in some embodiments a neutrophil-depleted prp composition to the damaged tissue are provided. In some variations, the compositions may be useful to treat ischemic heart disease and repair damaged cardiovascular tissue following acute myocardial infarction including congestive heart ...
Adjuvant therapy to standard of care (soc) diuretic treatment
Madeleine Pharmaceuticals Pty Ltd
January 26, 2017 - N°20170020899

A therapeutic method for treating and/or preventing diseases and medical conditions typically treated by administering diuretic agents (eg congestive heart failure). The method may comprise, for example, administering to a subject a diuretic agent in combination with vessel dilator (vsdl) or a variant or modified peptide thereof. The administration of the diuretic agent may be a component of a ...
Intrinsic frequency hemodynamic waveform analysis
California Institute Of Technology
January 19, 2017 - N°20170014039

Hardware and software methodology are described for cardiac health measurement. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the dicrotic notch. The intrinsic frequencies provide metrics/ measures that correlate to the cardiac health of the subject. The systems may be used for monitoring a condition and/...
Heart failure event detection using minimum heart rate
Cardiac Pacemakers, Inc.
January 05, 2017 - N°20170001005

Systems, devices, or methods can be used to detect an event, or series of events, that can indicate worsening of congestive heart failure (chf), or can be used to identify a subject at an elevated risk for developing chf. A chf event predictor can be provided using a characteristic minimum of subject cardiac intervals. In an example, the subject cardiac ...
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Intramyocardial patterning for global cardiac resizing and reshaping
Bioventrix, Inc.
November 24, 2016 - N°20160338831

Cardiomyopathy may be treated by distributing space-occupying agent within the myocardium in a pattern about one or more chambers of the heart, such that the space-modifying agent integrates into and thickens at least part of the cardiac wall about the chamber so as globally to reduce wall stress and stabilize or even reduce chamber size. Some patterns also cause a ...
Methods and compositions relating to p62/sqstm1 for the treatment and prevention of inflammation-associated diseases
Curelab Oncology, Inc.
November 10, 2016 - N°20160324944

Provided herein are novel p62 compositions for the modulation of expression of a proinflammatory cytokines, osteogenic transcription factors, a bone resorptive factors and endogenous p62. Consequently, such p62 compositions are useful for prophylaxis and treatment of inflammatory diseases and related methods. In certain embodiments the inflammatory diseases are not cancer-related. In various embodiments, the inflammatory diseases include, but are not ...
Steerable lesion excluding heart implants for congestive heart failure
Bioventrix, Inc.
October 27, 2016 - N°20160310276

Devices, systems, and methods for treating a heart of a patient may make use of one or more implant structures which limit a size of a chamber of the heart, such as by deploying a tensile member to bring a wall of the heart toward (optionally into contact with) a septum of the heart.
Methods for renal neuromodulation
Medtronic Ardian Luxembourg S.a.r.l.
October 13, 2016 - N°20160296279

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e. G., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment ...
Hemodynamic assist device
Hridaya, Inc.
October 06, 2016 - N°20160287771

A hemodynamic flow assist device includes a miniature pump, a basket-like cage enclosing and supporting the pump, and a motor to drive the pump. The device is implanted and retrieved in a minimally invasive manner via percutaneous access to a patient's artery. The device has a first, collapsed configuration to assist in implantation and a second, expanded configuration once deployed ...
Novel prodrug salts
Aeromics, Inc.
September 15, 2016 - N°20160264604

Provided are novel prodrug salts of selective aquaporin inhibitors, their use as pharmaceuticals, and pharmaceutical compositions comprising them, and novel processes for their synthesis and novel intermediates for use in their synthesis. Also provided is use of a compound for the prophylaxis, treatment, and control of aquaporin-mediated conditions. Aquaporin inhibitors, e. G., inhibitors of aqp4 and/or aqp2, may be ...
Devices, systems and methods for creation of peripherally located fistula
Rox Medical, Inc.
August 11, 2016 - N°20160228122

Devices, systems and methods are disclosed for the formation of an arteriovenous fistula in the limb of the patient. Embodiments include a device for the creation, modification and maintenance of a fistula that includes an integral fistula creation assembly near its distal end that passes through the skin of the patient, through a first vessel such as an artery, and ...
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