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Colorectal

Colorectal-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Systems and methods for determining optimum patient-specific antibody dose for tumor targeting
Memorial Sloan Kettering Cancer Center
May 17, 2018 - N°20180133350

The present disclosure describes a non-linear compartmental model using pet-derived data to predict, on a patient-specific basis, the optimal therapeutic dose of cargo carrying antibody (e. G., hua33) such as radiolabeled antibody, the antigen occupancy, residency times in normal and malignant tissues, and the cancer-to-normal tissue (e. G., colorectal cancer-to-normal colon tissue) therapeutic index. In addition, the non-linear compartmental model ...
NEW A novel complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist ...
Amal Therapeutics Sa
May 17, 2018 - N°20180133338

The present invention provides a novel complex for use in the prevention and/or treatment of colorectal cancer, the complex comprising a) a cell penetrating peptide, b) at least one antigen or antigenic epitope, and c) at least one tlr peptide agonist, wherein the components a)-c) are covalently linked. In particular, compositions for use in the prevention and/or ...
NEW Pharmaceutical composition for treating cancer and a method of using the same
Suzhou Institute Of Systems Medicine
May 17, 2018 - N°20180133214

The invention provides a pharmaceutical composition and a method for treating cancer, and the composition comprises a proteasome inhibitor and a nuclear export inhibitor. The composition has synergistic effects on treating cancers, particularly a solid tumor cancer. Specifically, the proteasome inhibitor bortezomib and crm1 inhibitor kpt330 induce apoptosis and cell cycle arrest in sensitive cells, such as hct116 and rko ...
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Synergistic enhancement of 5-fluorouracil cytotoxicity by deoxyuridine analogs in cancer cells
Stc.unm
May 10, 2018 - N°20180125875

In one embodiment, the invention provides a method of treating a subject who suffers from a neoplasm (including a cancer such as a radiotherapeutic-resistant cancer) by administering to the subject a therapeutically effective amount of (a) 5-formyl-2′-deoxyuridine (fdu or foudr) or a 5-formyl-2′-deoxyuridine derivative, optionally in combination with 5-hydroxy-2′-deoxyuridine (hudr); and (b) at least ...
Methods and systems for predicting colorectal cancer incidence and mortality
Liposcience, Inc.
April 26, 2018 - N°20180112274

Disclosed are methods and systems that uses glyca concentration in biosamples to evaluate risks of crc incidence and mortality.
Il-23-p19 vaccines
Affiris Ag
April 26, 2018 - N°20180110846

Disclosed is a vaccine, preferably for use in the prevention or treatment of an interleukin 23 (il-23) related disease, comprising a peptide bound to a pharmaceutically acceptable carrier, wherein said peptide is selected from the group qpeghhwetqqipsls (seq id no. 103; p8322), ghhwetqqipslspsqpwqrl qpeghhwetq (seq id no. 98; p8461), tqqipslspsq (seq id no. 99; p8400), qpeghhwetqqipslspsq (seq id no. 100; p9269), qpeghhwetqqipslsps (seq id no. 101; ...
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Colorectal Patent Applications
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inventor
  • 101+ full patent PDF documents of Colorectal-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Histamine-producing bacterial strains and their use in cancer
Biogaia Ab
April 19, 2018 - N°20180104287

The invention herein discloses histamine-producing bacterial strains for use in the prophylaxis, inhibition, treatment or reducing a risk of relapse of cancer, including colorectal cancer. The present invention also discloses the use of histamine-producing bacterial strains for manufacturing a medicament for treatment of cancer, including male colorectal cancer.
Combination therapy for cancer
Eli Lilly And Company
April 19, 2018 - N°20180104234

The present invention provides a method of treating squamous histology cancers and pi3k pathway activated large cell lung and colorectal cancers in a patient comprising administering to a patient in need of such treatment an effective amount of 8-[5-(1-hydroxy-1-methylethyl)pyridin-3-yl]-1-[(2s)-2-methoxypropyl]-3-methyl-1,3-dihydro-2h-imidazo[4,5-c]quinolin-2-one, or a pharmaceutically ...
Protein biomarker panels for detecting colorectal cancer and advanced adenoma
Applied Proteomics, Inc.
April 12, 2018 - N°20180100858

Disclosed herein are panels related to the diagnosis or recognition of advanced adenoma and colorectal cancer in a subject. The disclosed panels and related methods are used to predict or assess colon tumor status in a patient. They can be used to determine nature of tumor, recurrence, or patient response to treatments. Some embodiments of the methods include generating a ...
Method for identifying or detecting genomic rearrangements in a biological sample
Genomic Vision
April 12, 2018 - N°20180100202

A method for detection, visualization and/or comparison of polynucleotide sequences of interest using specially designed sets of long and short probes that enhance resolution and simplify visualization and detection. Probe compositions useful for practicing this method and procedures for identifying useful probes and probe combinations. These methods are useful for the detection of genomic rearrangements, especially those associated with ...
Method of diagnosing neoplasms
Commonwealth Scientific And Industrial Research Organisation
April 12, 2018 - N°20180100200

The present invention relates generally to nucleic acid molecules, the rna and protein expression profiles of which are indicative of the onset, predisposition to the onset and/or progression of a neoplasm. More particularly, the present invention is directed to nucleic acid molecules, the expression profiles of which are indicative of the onset and/or progression of a large intestine ...
Organic compositions to treat epas1 - related diseases
Arrowhead Pharmaceuticals, Inc.
April 12, 2018 - N°20180100151

The present disclosure relates to methods of treating epas1-related diseases such as cancer, metastases, astrocytoma, bladder cancer, breast cancer, chondrosarcoma, colorectal carcinoma, gastric carcinoma, glioblastoma, head and neck squamous cell carcinoma, hepatocellular carcinoma, lung adenocarcinoma, neuroblastoma, non-small cell lung cancer, melanoma, multiple myeloma, ovarian cancer, rectal cancer, renal cancer, clear cell renal cell carcinoma (and metastases of this and ...
Novel compounds as rearranged during transfection (ret) inhibitors
Glaxosmithkline Intellectual Property Development Limited
April 12, 2018 - N°20180099976

This invention relates to novel compounds which are inhibitors of the rearranged during transfection (ret) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to ...
Colorectal Patent Pack
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Colorectal Patent Applications
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inventor
  • 101+ full patent PDF documents of Colorectal-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Combined composition for preventing or treating cancer comprising a benzophenone thiazole derivatives as a vda ...
National Cancer Center
March 29, 2018 - N°20180085363

The present invention relates to a pharmaceutical combined composition for preventing or treating cancer comprising a compound of formula 1 or a pharmaceutically acceptable salt thereof and topoisomerase inhibitor as active ingredients. The pharmaceutical combined composition of the present invention specifically inhibits cell proliferation and induces apoptosis as to various cancers such as colorectal cancer and ovarian cancer that a vascular ...
Drug selection for colorectal cancer therapy using receptor tyrosine kinase profiling
Pierian Holdings, Inc.
March 22, 2018 - N°20180080934

The present invention provides methods for selecting a suitable anticancer drug therapy, and for identifying and predicting response, for the treatment of colorectal cancer. The present invention also provides methods for monitoring the status of colorectal cancer and monitoring how a patient with colorectal cancer is responding to anticancer drug therapy. The present invention further provides methods for the rational ...
Compositions and methods for preventing colorectal cancer
Trustees Of Tufts College
March 22, 2018 - N°20180078587

Provided herein are compositions and methods for preventing and/or reducing the risk of colorectal cancer. In particular, provided herein are probiotic and small molecule agents and their use in preventing colorectal cancer.
Novel aspirin derivatives and uses thereof
North Carolina Agricultural And Technical State University
March 15, 2018 - N°20180072652

The present invention provides novel aspirin derivatives useful for preventing and/or treating cancer. The novel compounds of this invention may be particularly useful for the prevention and/or treatment of cancers affecting the gastrointestinal system, such as colorectal cancer.
Anti-cancer activity of (e)-1-(3',4'-dimethoxyphenyl) butadiene
March 08, 2018 - N°20180064658

The present invention provides a method of using (e)-1-(3′,4′-dimethoxyphenyl) butadiene to induce anti-tumorigenic effects in pancreatic carcinoma, ovarian carcinoma, prostate carcinoma, colon carcinoma, lung carcinoma, lymphoblastoma, melanoma and colorectal carcinoma. The invention also provides a method of using (e)-1-(3′,4′-dimethoxyphenyl) butadiene to prevent cancer metastasis.
Biguanide compound and use thereof
Immunomet Therapeutics Inc.
February 15, 2018 - N°20180044283

The present invention relates to a guanidine compound and a use thereof, and more specifically, to a guanidine derivative showing excellent effects of inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence; a preparation method thereof; and a pharmaceutical composition containing the same as an active ingredient. Compared to existing drugs, the guanidine derivative according to the present invention shows ...
Novel peptides and combination of peptides for use in immunotherapy against various tumors
Immatics Biotechnologies Gmbh
February 08, 2018 - N°20180037627

A method of treating a patient who has hepatocellular carcinoma (hcc), colorectal carcinoma (crc), glioblastoma (gb), gastric cancer (gc), esophageal cancer, nsclc, pancreatic cancer (pc), renal cell carcinoma (rcc), benign prostate hyperplasia (bph), prostate cancer (pca), ovarian cancer (oc), melanoma, breast cancer (brca), cll, merkel cell carcinoma (mcc), sclc, non-hodgkin lymphoma (nhl), aml, gallbladder cancer and cholangiocarcinoma (gbc, ccc), urinary ...
Novel peptides and combination of peptides for use in immunotherapy against various tumors
Immatics Biotechnologies Gmbh
February 08, 2018 - N°20180037626

A method of treating a patient who has hepatocellular carcinoma (hcc), colorectal carcinoma (crc), glioblastoma (gb), gastric cancer (gc), esophageal cancer, nsclc, pancreatic cancer (pc), renal cell carcinoma (rcc), benign prostate hyperplasia (bph), prostate cancer (pca), ovarian cancer (oc), melanoma, breast cancer (brca), cll, merkel cell carcinoma (mcc), sclc, non-hodgkin lymphoma (nhl), aml, gallbladder cancer and cholangiocarcinoma (gbc, ccc), urinary ...
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