Images List Premium Download Classic

Codon

Codon-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


loading
Chimeric antigen receptors recognizing cancer-specific tn glycopeptide variants
The University Of Chicago
June 15, 2017 - N°20170166652

Disclosed are binding proteins, or fragments thereof, that specifically binds to a cancer-specific glycosylation variant of a protein and to a second epitope on the same protein, to a different protein presented on the same cell, or to a different protein presented on a different cell, such as an encoded polypeptide binding to both a cancer cell and an activated ...
Codon optimized nucleic acid encoding a retinitis pigmentosa gtpase regulator (rpgr)
Applied Genetic Technologies Corporation
June 15, 2017 - N°20170166617

This invention relates generally to a codon optimized nucleic acid encoding a retinitis pigmentosa gtpase regulator (rpgr) protein. The nucleic acid has enhanced stability during plasmid production relative to a wildtype cdna encoding the rpgr protein. The invention also relates to expression cassettes, vectors, and host cells comprising the codon optimized nucleic acid. Methods for preparing a recombinant adeno-associated (raav) ...
Methods and compositions for transgene expression in a herpesvirus vector system
President And Fellows Of Harvard College
June 15, 2017 - N°20170165336

Compositions are provided comprising a replication-competent herpesvirus vector system and/or a herpesvirus vector particle comprising a heterologous recombinant transgene of interest encoding an antigen of interest (e. G., a tumor-associated antigen, a microbial antigen, etc.), wherein the recombinant transgene has been modified to comprise a codon usage signature of a herpesvirus late gene operably linked to an active promoter. ...
Codon Patent Pack
Download 98+ patent application PDFs
Codon Patent Applications
Download 98+ Codon-related PDFs
For professional research & prior art discovery
inventor
  • 98+ full patent PDF documents of Codon-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Novel alpha-hydroxy carboxylic acid and derivatives and other gras based prodrugs of oxycodone and uses ...
Uniqure Ip B.v.
June 01, 2017 - N°20170152266

The invention describes pharmaceutical compounds and compositions comprised of a ligand attached to the opioid oxycodone, in a manner that substantially decreases or deters the potential for opioid abuse, addiction, illicit and illegal use, and overdose. When delivered at the proper dosage, the pharmaceutical composition provides therapeutic activity similar to that of the parent active agent.
Methods of manufacturing oral formulations
Purdue Pharma L.p.
June 01, 2017 - N°20170151229

A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and controlled release material.
Breast fibroadenoma susceptibility mutations and use thereof
Purdue Pharma L.p.
May 25, 2017 - N°20170145504

The present disclosure provides a method of assaying susceptibility and/or confirming diagnosis of breast fibroadenomas development in a human subject. Preferably, the method comprises the steps of performing a nucleic acid-based assay to analyze an isolated polynucleotide encoding at least exon 2 of med12 gene from a sample acquired from the human subject; and regarding the human subject with greater ...
Codon Patent Pack
Download 98+ patent application PDFs
Codon Patent Applications
Download 98+ Codon-related PDFs
For professional research & prior art discovery
inventor
  • 98+ full patent PDF documents of Codon-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Vectors with modified initiation codon for the translation of aav-rep78 useful for production of aav
Purdue Pharma L.p.
May 25, 2017 - N°20170145440

The present invention relates nucleic acid constructs for the production of recombinant parvoviral (e. G. Adeno-associated viral) vectors in insect cells, to insect cells comprising such constructs and to methods wherein the cells are used to produce recombinant parvoviral virions. The insect cells preferably comprise a first nucleotide sequence encoding the parvoviral rep proteins whereby the initiation codon for translation ...
Chimeric antigen receptors recognizing cancer-specific tn glycopeptide variants
Purdue Pharma L.p.
May 25, 2017 - N°20170145108

Disclosed are binding proteins, or fragments thereof, that specifically binds to a cancer-specific glycosylation variant of a protein and to a second epitope on the same protein, to a different protein presented on the same cell, or to a different protein presented on a different cell, such as an encoded polypeptide binding to both a cancer cell and an activated ...
Methods of providing analgesia
Purdue Pharma L.p.
May 25, 2017 - N°20170143697

A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and a sufficient amount of a controlled release material to render the dosage form suitable for twice-a-day administration to a human patient, the dosage form providing a c12/cmax ratio of 0. 55 to 0. 85, said ...
Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of ...
Purdue Pharma L.p.
May 25, 2017 - N°20170143696

The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present ...
Oligonucleotides and methods for detecting kras and pik3ca mutations
Siemens Healthcare Diagnostics Inc.
May 18, 2017 - N°20170137894

Provided are oligonucleotides that are capable of detecting kras and pik3ca mutations in both cancer patients and healthy individuals with high specificity in kpcr assays. When the oligonucleotides are used as forward primers in conjunction with a defined genotyping algorithm spreadsheet, the primers are capable of enhancing detection of kras codon 12, 13, and 61 and pik3ca codon 542, 545, and 1047 single nucleotide ...
Methods of manufacturing oral dosage forms
Purdue Pharma L.p.
May 18, 2017 - N°20170136006

A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and a sufficient amount of a controlled release material to render the dosage form suitable for twice-a-day administration to a human patient, the dosage form providing a c12/cmax ratio of 0. 55 to 0. 85, said ...
Pharmaceutical composition for treating cardio-cerebrovascular diseases and method for preparing the same
Purdue Pharma L.p.
May 11, 2017 - N°20170128514

A pharmaceutical composition, including, parts by weight of: 100-170 of a ginkgo flavone, 40-100 of a jujube extract, 100-200 of an extract of a peel of trichosanthes kirilowii, 30-60 of a saponin of codonopsis, 50-100 of a saponin of american ginseng, 40-70 of a saponin of radix astragalu, 20-50 of hirudin, 3-10 of a coenzyme q10, 40-100 of a longan ...
Codon Patent Pack
Download 98+ patent application PDFs
Codon Patent Applications
Download 98+ Codon-related PDFs
For professional research & prior art discovery
inventor
  • 98+ full patent PDF documents of Codon-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Computationally optimized broadly reactive antigens for h1n1 influenza
University Of Pittsburgh - Of The Commonwealth System Of Higher Education
April 27, 2017 - N°20170114102

Described herein is the generation of optimized h1n1 influenza ha polypeptides for eliciting a broadly reactive immune response to h1n1 influenza virus isolates. The optimized ha polypeptides were developed through a series of ha protein alignments, and subsequent generation of consensus sequences, based on selected h1n1 viruses isolated from 1918-2012. Provided herein are optimized h1n1 ha ...
Gene optimized hantaan virus m segment dna vaccine for hemorrhagic fever with renal syndrome
The Government Of The Unites States As Represented By The Secretary Of The Army
April 27, 2017 - N°20170112916

A synthetic, codon-optimized hantaan virus (htnv) full-length m gene open reading frame that consists of a unique nucleotide sequence encoding htnv proteins. This synthetic gene was cloned into a plasmid to form the first optimized htnv full-length m gene that elicits neutralizing antibodies in animals when delivered in combination with a similarly optimized puumala virus (puuv) dna vaccine. The invention ...
Pharmaceutical preparation containing oxycodone and naloxone
Purdue Pharma L.p.
April 27, 2017 - N°20170112828

The invention concerns a storage stable pharmaceutical preparation comprising oxycodone and naloxone for use in pain therapy, with the active compounds being released from the preparation in a sustained, invariant and independent manner.
Computationally optimized broadly reactive antigens for human and avian h5n1 influenza
University Of Pittsburgh - Of The Commonwealth System Of Higher Education
April 20, 2017 - N°20170107262

Described herein is the generation of optimized h5n1 influenza ha polypeptides for eliciting a broadly reactive immune response to h5n1 influenza virus isolates. The optimized ha polypeptides were developed through a series of ha protein alignments, and subsequent generation of consensus sequences, based on human and avian h5n1 isolates. Provided herein are optimized h5n1 ha polypeptides, ...
Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
Mallinckrodt Llc
April 06, 2017 - N°20170095470

The present disclosure provides an extended release pharmaceutical composition comprising hydrocodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating ...
Controlled release hydrocodone formulations
Purdue Pharma L.p.
March 30, 2017 - N°20170087153

A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and a sufficient amount of a controlled release material to render the dosage form suitable for twice-a-day administration to a human patient, the dosage form providing a c12/cmax ratio of 0. 55 to 0. 85, said ...
Methods of providing analgesia
Purdue Pharma L.p.
March 30, 2017 - N°20170087152

A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and controlled release material.
Controlled release hydrocodone formulations
Purdue Pharma L.p.
March 30, 2017 - N°20170087151

A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and controlled release material.
Loading