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Clinical Trial patents



      
           
This page is updated frequently with new Clinical Trial-related patent applications. Subscribe to the Clinical Trial RSS feed to automatically get the update: related Clinical RSS feeds. RSS updates for this page: Clinical Trial RSS RSS


System and method for managing genomic testing results

System and method for managing genomic testing results

Framework for modeling a clinical trial study using a cross-over treatment design

Framework for modeling a clinical trial study using a cross-over treatment design

Date/App# patent app List of recent Clinical Trial-related patents
11/20/14
20140341983
 Smart™ solid oral dosage forms patent thumbnailSmart™ solid oral dosage forms
Solid oral dosage forms (sodfs) comprising self monitoring and reporting therapeutics (smart™) adherence technology are provided which require no or minimal modification of clinical trial materials (ctms) or marketed drug while providing tamper resistant (literally foolproof) measurement of adherence that is highly accurate and without altering the chemical, manufacturing, and controls (cmc) of the ctm or marketed drug.. .
11/13/14
20140336943
 System and method for managing genomic testing results patent thumbnailSystem and method for managing genomic testing results
Various embodiments provide interfaces to access genomic testing information and incorporate it into daily physician practice. In some embodiments, presentation of genomic alteration data is simplified and/or coupled with contextual applications.
11/06/14
20140330572
 Framework for modeling a clinical trial study using a cross-over treatment design patent thumbnailFramework for modeling a clinical trial study using a cross-over treatment design
The present disclosure provides for modeling a clinical trial study, which may implement a cross-over design. A plurality of treatments is generated for a clinical trial study, based on a first subset of operational parameters.
11/06/14
20140329770
 Compositions comprising phytoestrogens receptor beta agonists and dietary fibers for chemopreventive treatment of sporadic adenomatous polyposis patent thumbnailCompositions comprising phytoestrogens receptor beta agonists and dietary fibers for chemopreventive treatment of sporadic adenomatous polyposis
It is herein discloses compositions comprising a blend of dietary phytoestrogens receptor β agonists and dietary fibers for prevention and treatment of sporadic adenomatous polyposis. The aforementioned compositions proved to be effect in a clinical trial enrolling patients prone to polyp recurrence and at intermediate risk for colorectal cancer (crc) development..
11/06/14
20140328525
 Image based clinical trial assessment patent thumbnailImage based clinical trial assessment
A method for assessing a treatment in a trial includes obtaining images generated from image data acquired at different times during a trial time period for a same region of interest of a subject. The treatment is administered to the subject for the trial.
10/30/14
20140324553
 Computer-assisted method for adaptive, risk-based monitoring of clinical studies patent thumbnailComputer-assisted method for adaptive, risk-based monitoring of clinical studies
A computer-assisted method is described for continuously assessing the quality of field data in a clinical study, identifying areas of weakness and specific sites where performance may be less than desirable, and flexibly allocating resources to address the problems, including the need to travel to the site to either check data or address problem areas. This method involves specification of key performance indicators that include elements that, preferentially, can be measured from a central location and do not require physical presence at the site to be checked.
10/23/14
20140316818
 Electronic health records in clinical trials patent thumbnailElectronic health records in clinical trials
A method for collecting self-reported data from an individual for use in a clinical trial is provided. The method includes providing a web site allowing the individual to store, organize, and access personal health records associated with the individual and sharing selected personal health records associated with the individual with a clinical trial sponsor.
10/23/14
20140316793
 Systems and methods for recruiting and matching patients for clinical trials patent thumbnailSystems and methods for recruiting and matching patients for clinical trials
Systems and methods provide for recruiting and matching patients for clinical trials using a network-based software platform which publicizes clinical trials, recruits patients for participation in the clinical trials, and obtains patient profile information to match patients with appropriate clinical trials based on medical and behavioral compatibility. Patients may be recruited to join clinical trials through online networking and referrals using social media and other electronic communication managed by the software platform.
10/23/14
20140316311
 Therapeutic method and apparatus using mechanically induced vibration patent thumbnailTherapeutic method and apparatus using mechanically induced vibration
A sleeve that provides mechanical stimulation to the arm to prevent bone density loss. A primary goal of this product is to prevent bone density loss that occurs during extended space travel.
10/23/14
20140315294
 Scalable lentiviral vector production system compatible with industrial pharmaceutical applications patent thumbnailScalable lentiviral vector production system compatible with industrial pharmaceutical applications
The present invention relates to the industrialization of the production of recombinant lentiviral vectors in order to manufacture sufficient materials for therapeutic applications such as gene therapy and/or dna vaccination, for use in clinical trials and/or commercial use.. .
10/16/14
20140310015
System and process for matching patients with available clinical trials
A system for matching patients to available clinical trials. The process includes a computer with a cpu having a processor, memory and an electronic database.
10/16/14
20140309590
Needle array assembly and method for delivering therapeutic agents
A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports.
10/09/14
20140303999
Method for creating and using registry of clinical trial participants
A method of screening participants for a clinical trial by obtaining a biometric sample from a prospective participant, generating a unique identifier code, populating a database with the unique identifier code and participant information and storing the database on computer readable media, and screening the participant for the clinical trial based on the unique identifier code and participant information. A method of screening participants for a clinical trial by obtaining personal information from a prospective participant, generating a unique identifier code, populating a database with the unique identifier code and participant information and storing the database on computer readable media, and screening the participant for the clinical trial based on the unique identifier code and participant information.
10/02/14
20140297311
Health care research, management and delivery system
A health care management and delivery system includes a hosted environment that provides health care treatment, diagnosis, and/or management. Health care providers are linked to one another and to a central network, which is linked to patient via the hosted environment.
10/02/14
20140297241
Reference model for disease progression
A method wherein reference disease models predict progression of disease within given populations, utilizing publically available clinical data and risk equations, to give a birds-eye view of clinical trials by allowing multiple trials to be systematically compared simultaneously via parallel processing/high performance computing which allows competition among alternative equations/hypothesis combinations; cross validation; and, then ranks results according to fitness via a fitness engine.. .
09/25/14
20140289001
System and method for recruiting subjects for research studies and clinical trials over the internet
A system and method for managing private records and other confidential information is provided, including a patient interface that allows patients to configure privileges for various parties to access various private records or portions thereof. A database can be accessed via a privacy engine, which respects the configured privileges and allows searching for private records.
09/18/14
20140278469
Systems and methods for tracking and designing clinical trials
Systems, apparatuses, and methods are provided for planning, activating, analyzing, and monitoring clinical trials. A planning process gathers clinical trial initiation parameters and produces a clinical trial plan.
09/04/14
20140249845
Clinical trials management system and method
System and method of managing a clinical trial in accordance with a protocol are provided. In accordance therewith, a workflow associated with the protocol is accessed from a first data structure.
09/04/14
20140249835
Methods and apparatus for data-driven monitoring
Methods and apparatus for facilitating monitoring in a clinical trial. The method includes acts of receiving data from at least one information technology system configured to process clinical trial data, and assigning a site prioritization to each of a plurality of sites for at least one clinical trial associated with the at least one information technology system.
08/21/14
20140236623
System and method for tracking clinical trial participation
A system and method for determining whether an individual is eligible to participate in a clinical trial by comparing partially identifying personal information of the subject to a database of partially identifying personal information of participants in other clinical trials and calculating the frequency of occurrence of the partially identifying personal information.. .
08/21/14
20140236620
Method and system for accessing patient data
Data concerning patients that have received treatment by a drug is stored and accessed to it is provided. One or more storage elements are provided that contain data concerning patients that have received the drug.
08/21/14
20140236618
Analyzing administrative healthcare claims data and other data sources
Techniques suitable for identifying potential subjects for a clinical trial and other applications are disclosed. One or more exclusion or inclusion criteria are defined for the clinical trial.
08/14/14
20140229198
Distributed randomization and supply management in clinical trials
A distributed clinical trial system that provides configurability, reusability and integration of randomization for different clinical trials with various electronic data capture (edc) systems. The distributed clinical trial system includes a method of randomizing subjects in a multi-arm clinical trial.
08/14/14
20140229197
Distributed randomization and supply management in clinical trials
A distributed clinical trial system that provides configurability, reusability and integration of randomization and inventory configurations for different clinical trials with various electronic data capture (edc) systems. The distributed clinical trial system includes a method of dispensing medication in a multi-arm clinical trial.
08/07/14
20140222448
Drug labeling tool
A tool for aiding a user author labels for drugs. The tool receives inputs that define requirements for a label, or aggregated requirements for a set of related labels.
08/07/14
20140222444
Method and system for clinical trial management
A method of managing a clinical trial includes verifying compliance with pre-determined data collection protocols in real time of medical data collected by peripheral clinical trial centers participating in the clinical trial, sending compliance verifications, collecting review reports submitted by the reviewers on the medical data, such as medical imaging data, according to a predetermined question-and-answer format, evaluating the answers in the review reports, for concordance, and transmitting at least one electronic notification pertaining to a result obtained from the evaluating, wherein at least one of the verifying, sending, collecting, evaluating, and transmitting is performed using at least one processor. A system for implementing the method also is provided..
08/07/14
20140222349
System and methods for pharmacogenomic classification
The invention provides a system and methods for the determination of the pharmacogenomic phenotype of any individual or group of individuals, ideally classified to a discrete, specific and defined pharmacogenomic population(s) using machine learning and population structure. Specifically, the invention provides a system that integrates several subsystems, including (1) a system to classify an individual as to pharmacogenomic cohort status using properties of underlying structural elements of the human population based on differences in the variations of specific genes that encode proteins and enzymes involved in the absorption, distribution, metabolism and excretion (adme) of drugs and xenobiotics, (2) the use of a pre-trained learning machine for classification of a set of electronic health records (ehrs) as to pharmacogenomic phenotype in lieu of genotype data contained in the set of ehrs, (3) a system for prediction of pharmacological risk within an inpatient setting using the system of the invention, (4) a method of drug discovery and development using pattern-matching of previous drugs based on pharmacogenomic phenotype population clusters, and (5) a method to build an optimal pharmacogenomics knowledge base through derivatives of private databases contained in pharmaceutical companies, biotechnology companies and academic research centers without the risk of exposing raw data contained in such databases.
08/07/14
20140221858
System and apparatus for providing diagnosis and personalized abnormalities alerts and for providing adaptive responses in clinical trials
A personalized real-time automated cardiovascular monitoring system monitors abnormalities in a patient's cardiovascular activity data through the use of individually adjusted electrocardiogram holter apparatus (holter/ecg device) that provides an automatic medical diagnosis of cardiac abnormalities and generates abnormality alert signals representative of certain abnormalities in patient's cardiac activities. The signals are transmitted using a wireless network through a bi-directional wireless protocol.
07/31/14
20140215490
Managing healthcare information in a distributed system
A system and method for managing healthcare information is disclosed. The data servers each include a data manager that comprises a controller, a grid engine, applications, an application manager and a user interface engine.
07/31/14
20140214448
Method and apparatus for verification of medication adherence
A system and method of confirming administration of medication in a clinical trial is provided. The method comprises the steps of receiving information identifying a particular medication prescription regimen in accordance with the clinical trial, determining one or more procedures for administering such prescription regimen and identifying one or more activity sequences associated with such procedures.
07/31/14
20140213608
Enhancement of impaired motor and mental functions, using dextromethorphan and oxidase enzyme inhibitor
During clinical trials on patients suffering from neurological disorders, it has been observed that some patients obtain dramatic improvements in motor control and/or higher mental functioning, when they receive a combination of dextromethorphan and quinidine, at suitable dosages. Improved motor control has been exemplified to date by improved ability to swallow and/or speak, among victims of stroke, head injury, or als.
07/31/14
20140213607

During clinical trials on patients suffering from neurological disorders, it has been observed that some patients obtain dramatic improvements in motor control and/or higher mental functioning, when they receive a combination of dextromethorphan and quinidine, at suitable dosages. Improved motor control has been exemplified to date by improved ability to swallow and/or speak, among victims of stroke, head injury, or als.
07/24/14
20140206561
Method for providing information on antidepressant therapeutic effect using single nucleotide polymorphism
Disclosed is a method for providing information on the therapeutic effect of an ssri antidepressant by identifying tph2 gene polymorphism rs4760815, slc6a4 gene polymorphism 5-httlpr, slc6a4 gene polymorphism rs2066713, gad1 gene polymorphism rs3828275, and grik2 gene polymorphism rs543196. Through the disclosed method, it is possible to select an antidepressant based on genetic information, to prevent the worsening or relapse of depression, and to establish customized depression treatment models which are effective in the development of customized new drugs, and appropriate for korean people.
07/17/14
20140200954
Research and development and market viability analysis framework for drugs, biologics and medical devices
A drug, biologic or medical device evaluation software tool for determining optimized research, development and commercialization pathways. The method comprises a) providing comparative clinical trial, value proposition and marketplace success predictors as metrics from a selected range of therapeutically relevant marketplace competitors anticipated at the time of the launch of the new product to a computer device b) assigning comparative benefit and risk scores to the product in research and development relative to these competitors c) incorporating specific feedback from physicians, health plans, healthcare service providers and payers to validate these scores d) offering scenario planning on multiple research, development and marketing options based on theoretical benefit and risk alternative scoring, and refined through various metric weighting and apportioning functions within the tool..
07/10/14
20140194467
Plasma cell disorders
The invention relates to novel biological markers for plasma cell disorders, such as multiple myeloma, and in particular to the use of micrornas as diagnostic and prognostic markers in assays for detecting such disorders. The invention also relates to methods of determining the efficacy of treating a plasma cell disorder with a therapeutic agent, and kits for carrying 5 out the assays and methods.
06/26/14
20140181098
Methods and systems for retrieval of experts based on user customizable search and ranking parameters
Methods and systems for finding experts based upon user customizable search and ranking criteria, and providing the search results at a person or expert level are disclosed. The methods generally entail cataloging data within one or more document databases, and includes the steps of (a) inputting disparate data sources which may include publications, awarded grants, clinical trials, and/or patents; (b) processing the data within each document in the document database(s); (c) creating a document profile for each document using relevant keywords; (d) assigning weighting factors to the relevant keywords based upon selected attributes; (e) assigning an identifier to each document and document author; (f) removing duplicate document data using a disambiguation algorithm; (g) extracting author level attributes from the retrieved documents; and (h) creating or updating each document profile.
06/12/14
20140164265
Clinical trial adverse event reporting system
A system is provided that sends data to a safety compliance management system in response to an adverse event. The system receives a first event in response to a first interaction by a user, where the first event indicates that the adverse event is to be reported to the safety compliance management system.
06/12/14
20140164015
Clinical trial adverse event data change reporting system
A system is provided that sends data changes to a safety compliance management system. The system defines at least one data field as a significant data field.
06/12/14
20140162901
Needle array assembly and method for delivering therapeutic agents
A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports.
06/12/14
20140162360
Needle array assembly and method for delivering therapeutic agents
A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports.
06/12/14
20140160436
System and method for evaluating intraocular lens performance
Systems and methods for providing improved techniques for evaluating performance of intraocular lenses. Such techniques can be used to evaluate lens designs and can help reduce the need for multiple clinical trials that may otherwise be needed to evaluate multiple design iterations.
06/12/14
20140158126
Drug delivery device for the treatment of patients with respiratory diseases
Drug delivery devices that include a microphone and processing circuitry that can detect operating events, such as peak inspiratory flow (pif) and breath actuated mechanism (bam) in dry powder inhalers can be used to improve clinical trials by providing information about the way in which the inhalers under test are being used.. .


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Clinical Trial topics: Clinical Trial, Clinical Trials, Compliance, User Interface, Scheduling, Graphical User Interface, Stem Cells, Disaccharide, Amniotic Fluid, Antioxidant, Antioxidants, Bovine Serum, Electronic Device, Portable Electronic Device, Operational Data Store

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