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Clinical Trial

Clinical Trial-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Biomarkers and methods relating to alzheimer's disease
King's College London
August 03, 2017 - N°20170219611

Alzheimer's disease, the most common cause of dementia in older individuals, is a debilitating neurodegenerative disease for which there is currently no cure. In the past, ad could only be definitively diagnosed by brain biopsy or upon autopsy after a patient died. These methods, which demonstrate the presence of the characteristic plaque and tangle lesions in the brain, are still ...
Methods for predicting risk of developing hypertension
Critical Care Diagnostics, Inc.
August 03, 2017 - N°20170219610

Methods using biomarkers, e. G., serum levels of st2, to predict risk of developing hypertension, as well as methods for treating subjects to reduce the risk of developing hypertension and methods for selecting and/or stratifying subjects for clinical trials of treatments to reduce the risk of hypertension.
Systems and method for implementing biomedical innovation datametrics dashboard
The Mitre Corporation
July 27, 2017 - N°20170213307

Systems and methods for implementing a biomedical innovations datametrics dashboard are presented. The dashboard can utilize data from real-world data sources to inform a simulation model which performs simulations of the biomedical innovation pipeline and related entities and processes. The dashboard can utilize the simulation model as well as feedback solicited from a user to assist in performing multi-objective optimization ...
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System and method for automatic unstructured data analysis from medical records
Dhristi Inc.
July 06, 2017 - N°20170193197

According to various embodiments, a method for automatic unstructured data analysis of medical data is provided. The method comprises receiving an unstructured data set corresponding to medical data. The unstructured data set includes data items from a first source and a second source. The method includes extracting, from the unstructured data set, a plurality of keywords and key phrases corresponding ...
Clinical trial patient retention and health maintenance system
Cerner Innovation, Inc.
July 06, 2017 - N°20170193194

Methods, systems, and computer-readable media are provided for computer based healthcare information to monitor medical parameters of patient and make healthcare recommendations so the patient's electronic medical record can be modified with warnings and healthcare recommendations. These warnings and recommendations can be used so that a clinical study participant does not fall out of the clinical study for not meeting ...
Methods of using gm604 in modulating als disease biomarkers leading to prognosis and therapeutic treatment ...
Genervon Biopharmaceuticals, Llc
June 08, 2017 - N°20170157197

Biomarkers are not as commonly used in als drug development as in the drug development process for oncology. Biomarkers are important component of the als drug development pathway to demonstrate drug effect and target engagement. In a recent phase 2a double-blind, randomized, placebo controlled clinical trial with gm604 (aka mntf, gm6), where als patients were treated with six doses of ...
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Clinical Trial Patent Applications
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Generating rtsm systems for clinical trials
4g Clinical, Inc.
June 01, 2017 - N°20170154168

Management (rtsm) system includes at least one programmable processor and a computer-readable medium storing instructions that, when executed, cause the at least one programmable processor to perform operations including: receiving and editing a specification for clinical trial in a specification editor, checking and improving quality of the specification by a specification checker, presenting the specification and providing feedback to a ...
Immerse software-as-a-service patient empowerment platform for clinical trial participants
Cytolon Digital Health Ag
June 01, 2017 - N°20170154166

The invention relates to system and a computer implemented method for use in the course of a clinical trial and/or precision medicine, wherein patient metrics are acquired and the system comprises selected core modules, methods and/or automated services and selected empowerment apps.
Methods and systems for predictive clinical planning and design
Cytolon Digital Health Ag
May 25, 2017 - N°20170147794

One example method for predictive clinical planning and design includes instantiating a plurality of data objects, each data object of the plurality of data objects comprising clinical trial information; displaying a graphical user interface on one or more display screens, the graphical user interface providing a graphical representation of at least a portion of a clinical trial and comprising a ...
System for remote monitoring and supervision of data
Cytolon Digital Health Ag
May 25, 2017 - N°20170147793

A system for remote monitoring and supervision of data, particularly for activities associated with clinical trials, which comprises: a first station, which pertains to an area in which the data are stored, the station being provided with first processing elements and elements for acquiring an item of information associated with the monitored data; a second station, provided with second processing ...
Electronic data document for use in clinical trial verification system and method
Cytolon Digital Health Ag
May 25, 2017 - N°20170147792

The present invention provides an electronic data document (edd) and related system and method for use in a computerized clinical trial verification system. In an exemplary embodiment, the edd is authenticated by the creator and validated by the receiver, and comprises an image of a source document (sd) that comprises a masked record of at least one interaction between a ...
System and method for identity and role base access management
Cytolon Digital Health Ag
May 25, 2017 - N°20170147790

The present disclosure relates to system(s) and method(s) for enabling role based privileged access to a user for accessing a plurality of applications. The system is configured to maintain a user profile in a profile database. The user profile stores authentication details and a functional role as well as application role and privilege level corresponding to each application ...
Monitoring device and a method of monitoring drug adherence in a clinical trial
Wipro Limited
May 18, 2017 - N°20170140128

The present disclosure relates to a monitoring device and a method of monitoring drug adherence in a clinical trial. In one embodiment, the monitoring device determines that an authenticated user has consumed the medication comprising the drug and further determines that the authenticated user who has consumed the drug is associated with the corresponding monitoring device. Furthermore, the monitoring device ...
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Predicting rapid decline in renal function in diabetes
University Of Dundee
April 27, 2017 - N°20170115310

Methods of predicting rapid decline in renal function in diabetes employing panels of biomarkers. The methods are useful for predicting risk of decline of renal function in individual subject and also for selecting subjects for clinical trials.
System and method for clinical trial candidate matching
Intelligent Medical Objects, Inc.
April 20, 2017 - N°20170109502

A computer-implemented system and method for identifying potential clinical trial participants from one or more databases of patient electronic health information includes analyzing the clinical trial requirements and mapping those requirements to an interface terminology, where concepts of the interface terminology include a key concept and a group of one or more additional concepts that are related in the context ...
System and method for evaluating risks of clinical trial conducting sites
Algorithm Inc
April 13, 2017 - N°20170103190

A computer implemented method for evaluating risks of clinical trial conducting sites is provided. The method includes steps of (i) obtaining a first data that corresponds to a first duration from the clinical trial conducting sites; (ii) performing a regression analysis on the first data to obtain a number of monitoring visit findings at a site in accordance with an ...
Solution for drug discovery
Northrop Grumman Systems Corporation
April 06, 2017 - N°20170098032

A drug discovery system may include a data platform and a drug discovery module. The data platform may be scalable to include a plurality of data sources. The data sources may include at least a clinical research database providing results of clinical trials. The drug discovery module may include a pharmaco-genomic mapper configured to provide a mapping of drugs to ...
Cell line-based redirected t-cell cytotoxicity assay
Aptevo Research And Development Llc
March 30, 2017 - N°20170089885

This disclosure provides a cell-based assay for testing the potency of multispecific binding molecules which specifically bind a t-cell antigen and a target antigen for redirected t-cell-mediated cellular cytotoxicity. The assay uses the tall-104 t-cell line as effector cells, and provides a sensitive, specific, and reproducible method for ensuring that purity, activity, and stability of multispecific binding molecule batches can ...
Methods of determining patient response by measurement of her-2 expression
Laboratory Corporation Of America Holdings
March 23, 2017 - N°20170082626

Methods are provided for determining or otherwise assessing the response of a patient to treatment, in particular, to cancer treatment. The methods include the analysis of samples for the presence or the absence of her2 markers alone or in conjunction with other biomarkers, such as her3 markers. In certain examples, the probable time to progression can be determined by first ...
Systems and methods for recording a collection of a sample of a patient
Sanis Biomedical Llc
March 09, 2017 - N°20170068803

The systems and methods described herein provide a smarttube collection and logging technique of a patient's (or clinical trial participant/subject) action of self-collection of a biologic sample during a sample collection event. The system for recording the sample collection event may include a shipping container comprising a sensor area, a switch and a microcontroller and sample collector positioned on ...
System for operating a clinical trial
Eclinicalhealth Limited
March 02, 2017 - N°20170061103

There is provided a system for operating a clinical trial, and a method for conducting a clinical trial using said system, wherein the system is capable of uniting all stakeholders in a single instance model. More particularly there is provided a paperless system for operating and management of data for a clinical trial which is capable of operating across different ...
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