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Clinical Trial

Clinical Trial-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Systems and methods for drug development
Transparency Life Science, Llc
November 09, 2017 - N°20170323083

Systems and methods are provided for drug development under a fully transparent development model. The model is configured to provide transparency to the patients, the researchers, clinicians, physicians, and any other registered users of the system who wish to contribute. According to various embodiments, the system and model enable drug development that leverage the combined wisdom and insight of the ...
System and method to produce and validate weighted relations between drug and adverse drug reactions
Transparency Life Science, Llc
November 02, 2017 - N°20170316175

A system to produce validated weighted relations between drugs and adverse drug reactions (adrs). At least one processor to monitor social media for links between drugs and adrs; extract a relation between a drug and an adr using named entity recognition to provide a weighted relation between the drug and the adr, the weight based on confidence of the link ...
Method for creating and using registry of clinical trial participants
Transparency Life Science, Llc
October 26, 2017 - N°20170308680

A method of screening participants for a clinical trial by obtaining identifying information chosen from a biometric sample, personal information, physical attributes, and combinations thereof from a prospective participant, optionally generating a unique identifier code, populating a database server with the unique identifier code and participant information and storing the information on non-transitory computer readable media, screening the participant for ...
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Analysis and verification of models derived from clinical trials data extracted from a database
Transparency Life Science, Llc
October 05, 2017 - N°20170286627

This disclosure describes frameworks and techniques directed to the analysis and verification of models extracted from a database. In some cases, the database can include an online database, such as clinicaltrials. Gov administered by the united states national institutes of health. In particular, this disclosure describes implementations that utilize models derived from clinical trial data extracted from a database and ...
Portable devices for detection of antibodies against therapeutic drugs
Transparency Life Science, Llc
October 05, 2017 - N°20170285023

Portable devices for anti-drug antibodies (adas) testing are provided. These devices can be used in various applications, including but not restricted to the following: uniform testing of patients for adas; selection of therapeutic drug for patient treatment; evaluation of the need to change therapeutic drug or to apply tolerance regimens; selection of patients for clinical trials; comparison of therapeutic drugs ...
Medication adherence monitoring system and method
Aic Innovations Group, Inc.
September 28, 2017 - N°20170277861

A medication management system is described that is operable to determine whether a user is actually following a protocol, provide additional assistance to a user, starting with instructions, video instructions, and the like, and moving up to contact from a medication administrator if it is determined that the user would need such assistance in any medical adherence situation, including clinical ...
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Clinical Trial Patent Applications
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Methods and systems for collecting spirometry data
Eresearchtechnology, Inc.
September 28, 2017 - N°20170273597

Disclosed herein are spirometers that can be used for assessment of pulmonary lung function. The disclosed systems, computer readable mediums and methods can be directed towards use in a variety of settings by health care professionals, clinical trial specialists, and individual users.
Method and system for improving site activation through critical path management and improving patient enrollment ...
Eresearchtechnology, Inc.
September 21, 2017 - N°20170270279

The present invention discloses methods for improving clinical trial planning and clinical trial operations deliverables. Specially, this invention introduces methods on shortening enrollment cycle time and/or improving more effective utilization of resources through critical path management in site activation and improvement of patient enrollment in focused site management.
Method of performing clinical trials
Eresearchtechnology, Inc.
August 24, 2017 - N°20170242979

An online clinical trial enrollment system enables patients to directly input their data for standardized processing. It has the steps of a. A patient-operated device for reading displayed commands and inputting responses; b. A server programmed to archive and process data from a plurality of patients, compare, analyze and aggregate information, perform statistical analysis and produce reports on a viewing ...
Biomarkers and methods relating to alzheimer's disease
King's College London
August 03, 2017 - N°20170219611

Alzheimer's disease, the most common cause of dementia in older individuals, is a debilitating neurodegenerative disease for which there is currently no cure. In the past, ad could only be definitively diagnosed by brain biopsy or upon autopsy after a patient died. These methods, which demonstrate the presence of the characteristic plaque and tangle lesions in the brain, are still ...
Methods for predicting risk of developing hypertension
Critical Care Diagnostics, Inc.
August 03, 2017 - N°20170219610

Methods using biomarkers, e. G., serum levels of st2, to predict risk of developing hypertension, as well as methods for treating subjects to reduce the risk of developing hypertension and methods for selecting and/or stratifying subjects for clinical trials of treatments to reduce the risk of hypertension.
Systems and method for implementing biomedical innovation datametrics dashboard
The Mitre Corporation
July 27, 2017 - N°20170213307

Systems and methods for implementing a biomedical innovations datametrics dashboard are presented. The dashboard can utilize data from real-world data sources to inform a simulation model which performs simulations of the biomedical innovation pipeline and related entities and processes. The dashboard can utilize the simulation model as well as feedback solicited from a user to assist in performing multi-objective optimization ...
Clinical trial/patient follow-up platform
The Mitre Corporation
July 27, 2017 - N°20170213015

A method and system is provided to improve the implementation of clinical trials by improving patient interaction and follow-up, data collection, and information processing in order to lower costs and cycle time of clinical trials. The invention and methods embodied produce a non-biased, more positive experience (easier, efficient) and reduce fragmentation of the follow-up process for clinical trial follow-up for ...
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Clinical trial patient retention and health maintenance system
Cerner Innovation, Inc.
July 06, 2017 - N°20170193194

Methods, systems, and computer-readable media are provided for computer based healthcare information to monitor medical parameters of patient and make healthcare recommendations so the patient's electronic medical record can be modified with warnings and healthcare recommendations. These warnings and recommendations can be used so that a clinical study participant does not fall out of the clinical study for not meeting ...
Methods of using gm604 in modulating als disease biomarkers leading to prognosis and therapeutic treatment ...
Genervon Biopharmaceuticals, Llc
June 08, 2017 - N°20170157197

Biomarkers are not as commonly used in als drug development as in the drug development process for oncology. Biomarkers are important component of the als drug development pathway to demonstrate drug effect and target engagement. In a recent phase 2a double-blind, randomized, placebo controlled clinical trial with gm604 (aka mntf, gm6), where als patients were treated with six doses of ...
Mobile chamber apparatuses and related methods
Inflamax Research Inc.
June 08, 2017 - N°20170156961

A mobile chamber apparatus includes a support structure of inflatable support members, and a chamber assembly. The inflatable support members may include transverse and upright sections. The chamber assembly may include a top wall, a bottom wall, and one or more side walls. Connectors may detachably couple the support structure and the chamber assembly. Installed, the support structure supports the ...
Generating rtsm systems for clinical trials
4g Clinical, Inc.
June 01, 2017 - N°20170154168

Management (rtsm) system includes at least one programmable processor and a computer-readable medium storing instructions that, when executed, cause the at least one programmable processor to perform operations including: receiving and editing a specification for clinical trial in a specification editor, checking and improving quality of the specification by a specification checker, presenting the specification and providing feedback to a ...
Immerse software-as-a-service patient empowerment platform for clinical trial participants
Cytolon Digital Health Ag
June 01, 2017 - N°20170154166

The invention relates to system and a computer implemented method for use in the course of a clinical trial and/or precision medicine, wherein patient metrics are acquired and the system comprises selected core modules, methods and/or automated services and selected empowerment apps.
Methods and systems for predictive clinical planning and design
Cytolon Digital Health Ag
May 25, 2017 - N°20170147794

One example method for predictive clinical planning and design includes instantiating a plurality of data objects, each data object of the plurality of data objects comprising clinical trial information; displaying a graphical user interface on one or more display screens, the graphical user interface providing a graphical representation of at least a portion of a clinical trial and comprising a ...
System for remote monitoring and supervision of data
Cytolon Digital Health Ag
May 25, 2017 - N°20170147793

A system for remote monitoring and supervision of data, particularly for activities associated with clinical trials, which comprises: a first station, which pertains to an area in which the data are stored, the station being provided with first processing elements and elements for acquiring an item of information associated with the monitored data; a second station, provided with second processing ...
Electronic data document for use in clinical trial verification system and method
Cytolon Digital Health Ag
May 25, 2017 - N°20170147792

The present invention provides an electronic data document (edd) and related system and method for use in a computerized clinical trial verification system. In an exemplary embodiment, the edd is authenticated by the creator and validated by the receiver, and comprises an image of a source document (sd) that comprises a masked record of at least one interaction between a ...
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