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This page is updated frequently with new Chromatography-related patent applications. Subscribe to the Chromatography RSS feed to automatically get the update: related Chromatography RSS feeds. RSS updates for this page: Chromatography RSS RSS


Injection-compression molded rotors

Injection-compression molded rotors

Date/App# patent app List of recent Chromatography-related patents
07/02/15
20150185191
 Lamp temperature management  liquid chromatography analyzers patent thumbnailnew patent Lamp temperature management liquid chromatography analyzers
A liquid sample analyzer includes a flow cell, a light source, and a lamp temperature management system. The flow cell is configured to receive a flow of a liquid sample from a liquid sample source.
07/02/15
20150184760
 Injection-compression molded rotors patent thumbnailnew patent Injection-compression molded rotors
A shear valve assembly for use in a high performance liquid chromatography system. The shear valve assembly includes a stator having a plurality of first fluid-conveying features; and a rotor having one or more second fluid-conveying features.
07/02/15
20150183843
 Glycoproteins having lipid mobilising properties and therapeutic applications thereof patent thumbnailnew patent Glycoproteins having lipid mobilising properties and therapeutic applications thereof
A biologically active lipid mobilising agent for use in therapy is disclosed which has the properties and characteristics of a zn-α2-glycoprotein, or of a fragment thereof having an apparent molecular mass mr greater than 6.0 kda as determined by gel exclusion chromatography. Methods of isolation and purification from biological material are also disclosed together with uses of the material for making up pharmaceutical compositions, especially pharmaceutical compositions useful for treating mammals to achieve weight reduction or for controlling obesity.
07/02/15
20150183820
 Scavenger containing protein formed from tandem-type multimer of mutant extracellular domain of protein g patent thumbnailnew patent Scavenger containing protein formed from tandem-type multimer of mutant extracellular domain of protein g
The present invention relates to a capturing agent for an antibody, immunoglobulin g or a protein comprising an fc region of the immunoglobulin g, wherein a protein consisting of a tandem-type multimer of extracellular domain mutants that have binding property to the protein comprising the fc region of the immunoglobulin g is immobilized to a water-insoluble solid support via mainly an amino group, and a column for a chromatography for separating and purifying the protein, which is filled with the capturing agent.. .
06/25/15
20150177199
 Method and  characterizing impurity profile of organic materials patent thumbnailMethod and characterizing impurity profile of organic materials
Method and apparatus for characterizing drug-modified polymers, macromolecules, proteins, antigens, antibodies or nanoparticles and quantitative determination of their impurity profile by two-dimensional liquid chromatography analysis. The first dimension is preferably size exclusion chromatography (sec)—which is also known as gel permeation chromatography in case of non-aqueous samples (gpc)—for complete molecular weight analysis of nanoscale particles.
Bbs Nanotechnology Ltd.
06/25/15
20150177148
 Crosstalk reduction patent thumbnailCrosstalk reduction
Techniques are disclosed relating to analysis and reduction of crosstalk between signals. These techniques may be applicable in many fields, such as single-tube pcr or dna melt analysis, pcr or melt data from neighboring wells of a multi-well plate, capillary electrophoresis data (e.g., dna sequencing), gas chromatography, multispectral imaging, dual-color fluorescence correlation spectrometry, electrical crosstalk, etc.
Luminex Corporation
06/25/15
20150176066
 Inspection tool for nucleic acid chromatography patent thumbnailInspection tool for nucleic acid chromatography
An inspection tool for nucleic acid chromatography includes an elongated porous sheet and a backing member. The porous sheet has a surface including a detection surface that has a strip-shaped indication portion where a nucleic acid probe for capturing the target nucleic acid is fixed.
Ngk Insulators, Ltd.
06/25/15
20150174553
 Porous composite particulate materials, methods of making and using same, and related apparatuses patent thumbnailPorous composite particulate materials, methods of making and using same, and related apparatuses
In an embodiment, a porous composite particulate material includes a plurality of composite particles. Each composite particle includes an acid-base-resistant core particle at least partially surrounded by one or more layers of acid-base-resistant shell particles.
Brigham Young University
06/18/15
20150170776
 Method and  the production of lead 212 for medical use patent thumbnailMethod and the production of lead 212 for medical use
The invention relates to a method for preparing lead (212) for medical use. This method comprises the production of lead (212) by the decay of radium (224) in a generator comprising a solid medium to which the radium (224) is bound, followed by the extraction of the lead (212) from the generator in the form of an aqueous solution a1, characterised in that the lead (212) contained in the aqueous solution a1 is purified from the radiological and chemical impurities, also contained in said aqueous solution, by a liquid chromatography on a column.
Areva Med Sas
06/18/15
20150168585
 Methods for compositional analysis of downhole fluids using data from nmr and other tools patent thumbnailMethods for compositional analysis of downhole fluids using data from nmr and other tools
Apparatus and methods of analyzing a composition of a hydrocarbon-containing fluid including using a nuclear magnetic resonance (nmr) tool to conduct a nmr relaxation measurement, a diffusion measurement, or both on the hydrocarbon-containing fluid to obtain nmr data, using a non-nmr tool to conduct an additional measurement of a reference fluid to obtain non-nmr data wherein the additional measurement comprises gas chromatography, optical observation, or both, and using the nmr data and the non-nmr data in an inversion process to determine an indication of the composition of the hydrocarbon-containing fluid. In some embodiments, the indication is determined over 4 chain length nodes..
Schlumberger Technology Corporation
06/18/15
20150166987

Programmable and reconfigurable microcolumn affinity chromatograpy device, system, and methods of use thereof


The present invention generally relates to microcolumn affinity chromatography devices, systems that include the microcolumn affinity chromatography devices of the present disclosure, methods of using the devices and the systems of the present disclosure, and methods of making the devices and the systems of the present disclosure. In certain embodiments, the microcolumn affinity chromatography device is suitable for conducting affinity chromatography in multiple microcolumns in parallel and/or in series..
Cornell University
06/18/15
20150166705

Method for producing polymer particles, polymer particles, filler for chromatography column, and chromatography column


To provide a method for producing polymer particles from an acrylamide monomer by a normal phase suspension polymerization method, polymer particles, a packing material for a chromatography column using the particles, and a chromatography column. A method for producing polymer particles, comprising dispersing a monomer composition comprising a multifunctional monomer having a plurality of n-substituted acrylamide groups in an aqueous medium; and polymerizing the dispersed monomer composition..
Jsr Corporation
06/18/15
20150166653

Low acidic species compositions and methods for producing and using the same using displacement chromatography


The present invention relates to low acidic species (ar) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods for producing such low ar compositions using displacement chromatography. Methods for using such compositions to treat a disorder, e.g., a disorder in which tnfα is detrimental, are also provided..
Abbvie, Inc.
06/18/15
20150166353

Porous silica powder


An object of the present invention is to provide a porous silica powder suitable for, for example, a gas chromatography support, and the porous silica powder has an average pore diameter of 0.5 to 10 μm as determined by a mercury intrusion method, a volume of pores having a 100 nm or smaller pore diameter of 0.2 cm3/g or less as determined by a nitrogen gas adsorption method, a specific surface area of 0.5 to 100 m2/g as determined by a nitrogen gas adsorption method, and a particle size distribution of 10 to 1000 μm.. .
Shinwa Chemical Industrial Ltd.
06/18/15
20150165343

Multidimensional liquid chromatography separation system and separation protein separation


A multidimensional liquid chromatography separation system has a mobile-phase storage tank, a first liquid transfer device, a second liquid transfer device, a first sample introduction device, a second sample introduction device, a separation device, a collection, storage device, at least two drainage devices and a flow path switching device. A separation method for protein separation using the multidimensional liquid chromatography separation system has the steps of: 1) preparation in advance, 2) the first dimensional separation, 3) collection and storage of the intermediate fraction, 4) the second dimensional or multidimensional separation and repeating the steps 3) and 4)..
Northwest University
06/18/15
20150165342

Apparatus and methods for preparative liquid chromatography


A method of liquid chromatography includes providing one or more solvent reservoirs, providing a solvent pump, drawing one or more solvents into the pump in response to a pressure drop that promotes outgassing of the solvents, and dispersing outgassed bubbles into smaller bubbles to promote re-dissolution of the gas. A liquid-chromatography apparatus includes at least two solvent reservoirs, a pump, at least one bubble-dispersing unit that receives a pressurized flow of proportioned solvents from the pump, and a control unit.
Waters Technologies Corporation
06/11/15
20150160203

Freeze-dried conjugate structure for point-of-care testing (poct) immunochromatography, immunoassay kit comprising the same, and analysis using the kit


In addition, the freeze-dried conjugate structure of the present invention can be provided in a state in which it is received in a chamber additionally comprising a cap. Thus, it can be stored without contamination and is easy to carry.
06/11/15
20150160173

Thin layer chromatography plates and related methods


In an embodiment, a method for manufacturing a thin layer chromatography (“tlc”) plate is disclosed. The method includes forming a layer of elongated nanostructures (e.g., carbon nanotubes), and at least partially coating the elongated nanostructures with a coating including silicon nitride.
Brigham Young University
06/11/15
20150160170

Chromatography column distribution system


A chromatography column distribution system includes a set of first bed support ribs extending radially from an inner, first radial position near the centre of the plate to an outer radial position nearer to the periphery of the plate and at least one set of intermediate bed support ribs starting at an intermediate radial position and extending to an outer radial position nearer to the periphery of the plate. Channels are formed between adjacent bed support ribs.
Ge Healthcare Bio-sciences Ab
06/11/15
20150158877

Dualistic substituted phthalocyanine zinc formula, process of separating the same and use thereof


The invention discloses a pharmaceutical formula used in photodynamic therapy (pdt) for cancer or precancerous lesions. The formula includes four components of disulfonic acid diphthaloyl iminomethyl dualistic substituted phthalocyanine zinc alkali salt.
Fuzhou University
06/11/15
20150157959

Techniques for accelerating thermal equilibrium in a chromatographic column


Techniques are described for accelerating thermal equilibrium in a chromatographic column. An apparatus comprises a chromatography column, and a plurality of temperature control units in thermal contact with the chromatography column.
Waters Technologies Corporation
06/04/15
20150151276

Chromatography media and use thereof


The present invention relates to a novel non-cross linked chromatography media provided with glutathione ligands which may or may not be provided with magnetic particles. The chromatography media is used for production of an affinity media provided with gluthatione ligands for adsorption of gst-tagged proteins..
Ge Healthcare Bio-sciences Ab
05/28/15
20150148545

Protein tyrosine phosphatase inhibitor, preparation method and uses thereof


Disclosed in the present invention is a protein tyrosine phosphatase inhibitor. The preparation method therefor is: extracting the crude product from the isaria fumosorosea wize solid or liquid fermentation broth using ethyl acetate, ethanol, methanol, or a mixed solvent of chloroform and methanol; separating the obtained extract using column chromatography on silica gel; and obtaining the target product.
Hebei University
05/28/15
20150147451

Novel food and feed antioxidants and preservatives based on antioxidant enzymes extracted from animal blood


Disclosed is a process for extracting an antioxidant cocktail (containing a number of antioxidative molecules including but not limited to superoxide dismutase (sod), catalase, glutathione, glutathione peroxidase) from animal sources (i.e., blood or liver) so that it can be used as a food and feed preservative in a non-purified state to prevent rancidity. The antioxidant can also be used in other products such as oils, paint, caulking, plastics, or any other product exposed to oxidation.
Clemson University
05/28/15
20150144782

Systems, devices, and methods for connecting a chromatography system to a mass spectrometer


The invention provides interfaces between analytical instruments, e.g., between chromatography systems and mass spectrometers. In an exemplary embodiment, an ion source is provided for connecting a carbon dioxide-based chromatograph device to a mass spectrometer.
Waters Technologies Corporation
05/28/15
20150143880

High performance liquid chromatography with uv-visible detection


Apparatus and methods for high performance liquid chromatography. The apparatus includes a preparation loop comprising two linear stepping pumps, a sample loop comprising a sample injector, a chromatography column, and a detector device.
Academia Sinica
05/21/15
20150141688

Purification of chlorosilanes using chromatography


The present invention relates to a method for separating organohalosilanes. The method includes introducing a mixture including at least a first organohalosilane and a second organohalosilane onto a chromatographic bed including a stationary phase.
Dow Corning Corporation
05/21/15
20150141623

Protein purification methods to reduce acidic species


The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the amount of charge variants, aggregates, and fragments of a protein of interest, as well as host cell proteins, present in purified preparations by applying particular chromatography conditions during such protein purification.. .
Abbvie, Inc.
05/21/15
20150140600

Mass spectrometry quantitation of p450 isoforms in hepatocytes


A method for screening a drug for cytochrome p450 (cyp) induction is provided and can include incubating the drug with a microsome-containing biological sample and then quantitating at least one cytochrome p450 isoform. The isoforms can be selected from 2b6, 3a4, 1a2, and 3a5 isoforms.
Dh Technologies Development Pte. Ltd.
05/21/15
20150140593

Retention index standards for liquid chromatography


A homologous series of neutrally charged compounds having at least one functional group bearing a positive charge and at least one functional group bearing a negative charge are advantageous retention index standards for liquid chromatography, especially for liquid chromatography-mass spectrometry (lc-ms) methods, more especially for lc-ms methods employing electrospray (esi) or atmospheric pressure chemical ionization (apci) ionization systems.. .
National Research Council Of Canada
05/21/15
20150140266

Biaxially stretched polypropylene film for capacitors


A biaxially stretched polypropylene film for a capacitor containing an isotactic polypropylene. The weight average molecular weight (mw) of the isotactic polypropylene as measured by gel permeation chromatography (gpc) is 250,000 to 450,000, the molecular weight distribution mw/mn is 7 to 12 and mz/mn is 20 to 40, and the value of a difference obtained by subtracting a differential distribution value when the logarithmic molecular weight log(m)=6 from a differential distribution value when log(m)=4.5 on a molecular weight distribution curve thereof is 8% to 20%.
Oji Holdings Corporation
05/21/15
20150139944

Separatone-based protein expression and purification platform


Provided is a separatome-based recombinant peptide, polypeptide, and protein expression and purification platform based on the juxtaposition of the binding properties of host cell genomic peptides, polypeptides, and proteins with the characteristics and location of the corresponding genes on the host cell chromosome, such as that of e. Coli, yeast, bacillus subtilis or other prokaryotes, insect cells, mammalian cells, etc.
Board Of Trustees Of The University Of Arkansas
05/21/15
20150136700

Chromatographic materials


The present invention provides a chromatographic stationary phase material various different types of chromatography. One example chromatographic stationary phase is represented by formula 1 [x](w)a(q)b(t)c (formula 1).
Waters Technologies Corporation
05/21/15
20150135861

Pre-column heating of mobile phase solvent in chromatography systems


An apparatus for heating a flowing fluid includes a tubing assembly, a heater block made of thermally conductive material, and a heater cartridge in thermal communication with the heater block. The heater cartridge is configured to provide heat to the heater block for transfer to fluid flowing through the tubing assembly.
Waters Technologies Corporation
05/14/15
20150133294

Chromatographic materials


In one aspect, the present invention provides a chromatographic stationary phase material for various different modes of chromatography represented by formula 1: [x](w)a(q)b(t)c (formula 1). X can be a high purity chromatographic core composition having a surface comprising a silica core material, metal oxide core material, an inorganic-organic hybrid material or a group of block copolymers thereof.
05/14/15
20150132781

Multiplexed chromatography-immunoassay the characterization of circulating immune complexes


Thus, herein is reported a method for analyzing/characterizing circulating immune complexes (cics) formed in vivo comprising a size-exclusion chromatography of a sample obtained from a mammal to which the drug had been administered at least once for determining the weight/size of the immune complexes, optionally a second non-sec chromatography, and at least one immunoassay, whereby the immune complex is characterized by the correlation of the immune complex size and the immunoassay result/read-out. Also reported herein is the use of a method as reported herein for determining a correlation to altered pharmacokinetics, for determining loss or reduction of efficacy, for determining neutralization of natural counterparts of the drug, for determining immune and hypersensitivity reactions, including serum sickness/type iii hypersensitivity reaction/immune complex-mediated disease..
05/14/15
20150132241

Antiperspirant active compositions having sec chromatogram exhibiting high sec peak 4 intensity


An aluminum salt composition comprising (a) an aluminum salt having an aluminum to chloride molar ratio of about 0.3:1 to about 3:1, an oh:al molar ratio of about 2:1 to about 2.6:1, exhibiting a size exclusion chromatography (sec) chromatogram having a sec peak 4 to peak 3 intensity ratio of at least 7, and a peak 4 intensity greater than a peak 5 intensity in aqueous solution, and (b) at least one buffer chosen from an amino acid, glycine, and betaine, wherein a molar ratio of buffer to aluminum is about 0.1:1 to about 3:1.. .
05/14/15
20150129501

Flash chromatography column apparatus


A flash chromatography apparatus which provides an improved apparatus for large and medium commercial scale flash chromatography columns. More particularly, the invention relates to a flash chromatography column and cartridge system for positioning and ease of loading and unloading of stationary phase agent in the flash chromatography column.
05/14/15
20150129474

Techniques for thermally insulating a liquid chromatographic column


An apparatus for performing liquid chromatography includes a chromatography column, and an insulating member surrounding the chromatography column wherein the insulating member is formed from a vacuum chamber surrounding the chromatography column. Another apparatus for performing liquid chromatography includes a chromatography column, and an insulating member surrounding the chromatography column, wherein the insulating member includes aerogel.
05/14/15
20150128685

Sampling device


The invention relates to a sampler for providing a sample for high-performance liquid chromatography, in which a volume of liquid to be taken up into a cylinder can be aspirated by means of a first drive and can be compressed to a high pressure level by means of a second drive independent of the first drive or can be decompressed from this level in a controlled manner.. .
05/07/15
20150126764

Method for the purification of prostaglandins


The present invention provides a method for the purification of a prostaglandin by supercritical fluid chromatography, said method comprising the use of a stationary phase and a mobile phase comprising carbon dioxide, provided that when the stationary phase is unmodified silica gel, the prostaglandin is not luprostiol. The invention also provides prostaglandins obtainable by the method..
Johnson Matthey Public Limited Company
05/07/15
20150126760

Highly unsaturated fatty acid or highly unsaturated fatty acid ethyl ester with reduced environmental pollutants, and producing same


A highly unsaturated fatty acid or a highly unsaturated fatty acid ethyl ester that has been produced using as a feedstock oil a fat or oil that contains highly unsaturated fatty acids as constituent fatty acids and which has been reduced in the contents of environmental pollutants, wherein among the dioxins contained, polychlorinated dibenzoparadioxins (pcdds) and polychlorinated dibenzofurans (pcdfs) are contained in amounts of less than 0.05 pg-teq/g and coplanar pcbs (co-pcbs) in amounts of less than 0.03 pg-teq/g. Also disclosed is a method for producing the highly unsaturated fatty acid or highly unsaturated fatty acid ethyl ester by the steps of removing free fatty acids and environmental pollutants by thin-film distillation from a feedstock oil, ethyl esterifying the resulting fat or oil, and refining the same by rectification and column chromatography..
Nippon Suisan Kaisha, Ltd.
05/07/15
20150126715

Highly glycosylated long-acting human growth hormone protein and production same


The present invention relates to a long-acting human growth hormone nexp-hgh protein and its production method. More specifically, it relates to a specific isoform of long-acting human growth hormone nexp-hgh protein in which human growth hormone is fused with a highly glycosylated alpha-1 antitrypsin mutant whereby long-acting properties in vivo are increased.
Alteogen, Inc.
05/07/15
20150126700

Curable resin composition and cured product thereof, encapsulating agent, and optical semiconductor device


The curable resin composition includes a compound (u) containing an aliphatic carbon-carbon unsaturated bond and a compound (h) containing a hydrosilyl group and includes at least one of a ladder-type silsesquioxane [a1] and a ladder-type silsesquioxane [a2], where the ladder-type silsesquioxane [a1] contains an aliphatic carbon-carbon unsaturated bond and has a number-average molecular weight of 500-1500 and a molecular weight dispersity (mw/mn) of 1.00-1.40 as determined by gel permeation chromatography and calibrated with a polystyrene standard, and the ladder-type silsesquioxane [a2] contains a hydrosilyl group and has a number-average molecular weight of 500-1500 and a molecular weight dispersity (mw/mn) of 1.00-1.40 as determined by gel permeation chromatography and calibrated with a polystyrene standard.. .
05/07/15
20150126403

Method of identifying proteins in human serum indicative of pathologies of human lung tissues


A method of identifying proteins present in human serum which are differentially expressed between normal individuals and patients known to have non-small cell lung cancers and asthma, as diagnosed by a physician. Human serum specimens from each population are digested with trypsin or any other suitable endoproteinase and analyzed using a liquid chromatography electrospray ionization mass spectrometer.
Cancer Prevention And Cure, Ltd
05/07/15
20150125877

Weak affinity chromatography


The present invention provides methods for analyzing a target compound from a biological sample. In one aspect, a method for analyzing a target compound in a biological sample can comprise delivering a biological sample through an affinity column, the affinity column having a binding ligand coupled to a stationary structural support, wherein the affinity column has a high density of the binding ligand per the stationary structural support and wherein the binding ligand has been preselected to cause weak affinity separation zonal retardation of the target compound from the biological sample forming a target compound fraction and a biological sample fraction and detecting the target compound by mass spectrometry..
05/07/15
20150125859

Nucleic acid chromatography method, composition for nucleic acid chromatography and kit containing same


Provided is a nucleic acid chromatography method ensuring a stable detection state, and a composition and kit for use in nucleic acid chromatography. For this purpose, the nucleic acid chromatography method is provided with a step of performing chromatography by supplying a chromatography liquid containing a target nucleic acid to a solid-phase carrier on which is fixed a detection probe capable of capturing the nucleic acid, wherein the chromatography liquid contains one or two or more kinds of water-soluble polymers..
Ngk Insulators, Ltd.
05/07/15
20150123399

High pressure fitting with self-releasing ferrule


A fitting assembly is provided having a nut and a self-releasing ferrule, which in certain embodiments may be assembled by an operator. The fitting assembly includes a nut with a first end, and a second end that defines a slot, and a ferrule with a first end that defines one or more slots, and a second end, with the second end of the nut adapted to receive the first end of the ferrule, the second end of the ferrule adapted to be received in a component or fitting of a liquid chromatography system.
Idex Health & Science Llc
05/07/15
20150122988

Chromatography apparatus and methods using multiple microfluidic substrates


An apparatus for chemical separations includes a first substantially rigid microfluidic substrate defining a first fluidic port; a second substantially rigid microfluidic substrate defining second fluidic port; and a coupler disposed between the first and second substrates, the coupler defining a fluidic path in fluidic alignment with the ports of the first and second substrates. The coupler includes a material that is deformable relative to a material of the first substrate and a material of the second substrate.
Waters Technologies Corporation
05/07/15
20150122365

Components with an atomic layer deposition coating and methods of producing the same


Liquid chromatography and gas chromatography components with a conformal protective coating on internal surfaces thereof and methods for producing the same are provided. The conformal protective coating is formed via an atomic layer deposition (ald) process.
Agilent Technologies, Inc.
05/07/15
20150121996

Automated sample injection apparatus, multiport valve, and methods of making and using the same


Automated sample injection apparatus, multiport valves, and chromatography systems containing an automated sample injection apparatus and/or a multiport valve are disclosed. Methods of making and using automated sample injection apparatus and multiport valves within chromatography systems are also disclosed..
Alltech Associates, Inc.
04/30/15
20150119605

Process for the preparation of pillar[5]quinone


The present invention relates to a process for the preparation of pillar[5]quinone and further relates to an easy-to-operate and chromatography-free process for the preparation of crystalline pillar [5] quinone by the oxone/iodobenzene-mediated oxidative de-aromatization of readily available 1,4-dimethoxypillar[5] arenes in good. .
Council Of Scientific & Industrial Research
04/30/15
20150118675

Immunochromatography detection method


The present invention provides an immunochromatography detection method capable of suppressing non-specific reactions. The present invention relates to an immunochromatography detection method including: a step of adding an analyte dilution solution containing an analyte to a chromatography medium; a step of recognizing a detection target by a labeling substance modified with gold nanoparticles, which is dry-retained at a labeling substance retaining part; a step of developing a composite of the labeling substance and the detection target as a mobile phase; and a step of detecting the detection target in the developed mobile phase at a judgment part, wherein the labeling substance is protected with a polyalkylene glycol having one or more mercapto groups and/or a derivative thereof and then dry-retained together with arginine and casein at the labeling substance retaining part..
Tanaka Kikinzoku Kogyo K.k.
04/30/15
20150115151

Ion mobility spectrometer


A method and apparatus are disclosed for improving ion mobility spectrometry by using a fast and spatially wide ion gate based on local rf field barrier opposed to a switching dc field. The improvement accelerates the ion mobility analysis and improves charge throughput and dynamic range of the ims.
Leco Corporation
04/23/15
20150112609

Plus-fraction corrections for heavy hydrocarbon liquids


A method of determining the plus-fraction correction for a heavy oil sample including analyzing the heavy oil sample using gas chromatography, selecting an elution ratio based on the percentage of plus-fraction elution, applying the elution ratio to provide a maximum carbon number and a plus-fraction correction to compensate for the non-elution of the plus-fraction. An elution ratio as a function of the percentage of c60+ elution is provided.
Weatherford Canada Partnership
04/23/15
20150111844

Polyphenol composition


A polyphenol composition derived from camellia sinensis and contains flavonol aglycones and flavonol glycosides, in a weight ratio [(b)/(a)] of the following total contents (b) to (a) is from 0.01 to 18, wherein (a) total content of the flavonol aglycones contained in solids of the polyphenol composition after hydrolysis as measured by high-performance liquid chromatography, and (b) total content of the polyphenols contained in solids of the polyphenol composition as measured by the ferrous tartrate method.. .
Kao Corporation
04/23/15
20150111307

Organic colored microparticles, diagnostic reagent kit containing the same, and in vitro diagnosis method


Provided are an immunochromatography kit that is highly sensitive and capable of multicoloration, and organic colored microparticles that are ideal as an element of the immunochromatography kit. Organic colored microparticles having an average grain size between 10 and 1,000 nm and a color intensity between 1.0 and 5.0 are prepared using cellulose as the starting material.
Asahi Kasei Fibers Corporation
04/23/15
20150111305

Multielectrode electrolytic device and method


An electrolytic device comprising: a central sample flow channel, first and second regenerant flow channels, first and second charged barriers disposed between said sample flow channel and first and second regenerant flow channels, and pairs of oppositely charged, spaced electrodes disposed in the regenerant flow channels. Also, electrolytic devices with a different electrode configuration are described.
Dionex Corporation
04/23/15
20150111025

Dispersion liquid of carbon nanotube-containing composition and conductive molded body


The present invention relates to a dispersion liquid of a carbon nanotube-containing composition which contains a carbon nanotube-containing composition, a dispersant with a weight-average molecular weight of 5,000 to 60,000 as determined by gel permeation chromatography, and an aqueous solvent. The present invention provides a dispersion liquid of a carbon nanotube-containing composition which shows high dispersibility on a base while maintaining high dispersibility for the carbon nanotube-containing composition..
Toray Industries, Inc.
04/23/15
20150111023

In-situ heated deposition of parylene to enhance pore penetration into silicone


Coating porous material, such as pdms, with parylene n, c, d, and af-4 by vapor deposition polymerization is described in which a temperature of the porous material's surface being coated is heated to between 60° c. And 120° c., or 80° c.
California Institute Of Technology
04/23/15
20150110862

Sweet gum fruit extract as a therapeutic agent


Sweet gum (liquidambar styraciflua l., family hamamelidaceae) fruit extract was discovered to possess potent activities against multiple targets of the pi3k (phosphatidylinositide 3-kinase) pathway, especially the pi3k/akt and mtor pathways. At a very low concentration of 1.85 μg/ml (ic50), sweet gun extract showed the ability of simultaneously blocking the pathways of pi3k/akt (upstream), mtor (mammalian target of rapamycin) (downstream), as well as its downstream protein products s6k and s6.
Board Of Regents
04/23/15
20150110803

Low acidic species compositions and methods for producing and using the same using displacement chromatography


The present invention relates to low acidic species (ar) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods for producing such low ar compositions using displacement chromatography. Methods for using such compositions to treat a disorder, e.g., a disorder in which tnfα is detrimental, are also provided..
Abbvie, Inc.
04/23/15
20150107334

Continuous measurement chromatography and continuous stochastic perturbation chromatography


A method and system for continuous measurement chromatograph involves stochastically modulating a system variable. The sample can be introduced into a chromatography column.
Massachusetts Institute Of Technology
04/23/15
20150107332

Microfluidic contaminant trap for trapping contaminants in gas chromatography


Microfluidic contaminant traps of certain representative embodiments illustratively comprise: an inlet configured to connect directly or indirectly to a sample inlet of a gas chromatography (gc) system; an outlet configured to connect directly to an inlet of a gc column or indirectly to the gc column via another fluidic component; an interlayer comprising a channel; an upper layer disposed over and bonded to the interlayer; and a coating disposed over the channel. The coating reduces interactions of analytes from a sample provided at the inlet of the microfluidic contaminant trap with the microfluidic contaminant trap..
Agilent Technologies, Inc.
04/23/15
20150107331

Integrated hydrocarbon analysis


Petroleum or other hydrocarbon samples can be analyzed in parallel by 1) gc-field ionization time of flight mass spectrometer (gc-fi-tof ms) and 2) two dimensional gas chromatography (2d-gc) equipped with a flame ionization detector (fid). The combined techniques allow for improved quantitative characterization of the compounds within a hydrocarbon sample.
Exxonmobil Research And Engineering Company
04/16/15
20150106029

Method of characterizing crude oil by high pressure liquid chromatography


A system and a method are provided for calculating the cetane number, octane number, pour point, cloud point and aniline point of a crude oil fractions from the density and high pressure liquid chromatography (hplc) of a sample of the crude oil.. .
04/16/15
20150104849

Methods of purifying recombinant adamts13 and other proteins and compositions thereof


Provided herein are methods for purifying recombinant a disintegrin-like and metallopeptidase with thrombospondin type 1 motif 13 (adamts13) protein from a sample. The method comprises enriching for adamts13 protein by chromatographically contacting the sample with hydroxyapatite under conditions that allow adamts13 protein to appear in the eluate or supernatant from the hydroxylapatite.
Baxter International Inc.
04/16/15
20150104833

Novel protein having b-glucosidase activity and uses thereof


By combination of hydrophobic chromatography and strongly basic anion-exchange chromatography, a novel, highly hydrophobic β-glucosidase was successfully identified from acremonium cellulolyticus. Further, a gene corresponding to the identified β-glucosidase was isolated.
Meiji Seika Pharma Co., Ltd.


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Chromatography topics: Chromatography, Chromatograph, Antibodies, Mass Spectrometry, Spectrometry, Quantitative, High Resolution, Switching Valve, Cross Section, Protein A Affinity Chromatography, Amino Acid, Silica Gel, Carboxylic Acid, Antifungal, Isoleucine

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