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Cholesterol patents



      
           
This page is updated frequently with new Cholesterol-related patent applications. Subscribe to the Cholesterol RSS feed to automatically get the update: related Cholesterol RSS feeds. RSS updates for this page: Cholesterol RSS RSS


Date/App# patent app List of recent Cholesterol-related patents
09/25/14
20140288187
 Cocoa-based food products patent thumbnailnew patent Cocoa-based food products
The invention is concerned with food products comprising one or more cocoa bean products and a carotenoid compound, particularly with food products which are, or comprise, chocolate. The products of the invention may be used in reducing elevated total cholesterol, triglycerides and inflammatory damage, as well as improving tissue microcirculation and tissue oxygenation..
09/25/14
20140288072
 5 - benzylaminomethyl - 6 - aminopyrazolo [3, 4 -b] pyridine derivatives as cholesteryl ester-transfer protein (cetp) inhibitors useful for the treatment of atherosclerosis patent thumbnailnew patent 5 - benzylaminomethyl - 6 - aminopyrazolo [3, 4 -b] pyridine derivatives as cholesteryl ester-transfer protein (cetp) inhibitors useful for the treatment of atherosclerosis
The present application relates to a series of substituted pyra-zolopyridin-6-amines having the general formula (i), including their stereoisomers and/or their pharmaceutically acceptable salts. Wherein r, r1, r2, ra, raa, rb and n are as defined herein.
09/25/14
20140287994
 Peptides having reduced toxicity that stimulate cholesterol efflux patent thumbnailnew patent Peptides having reduced toxicity that stimulate cholesterol efflux
The present invention provides a family of non-naturally occurring polypeptides having cholesterol efflux activity that parallels that of full-length apolipoproteins (e.g., apo ai and apo e), and having high selectivity for abca1 that parallels that of full-length apolipoproteins. Further, the peptides of the invention have little or no toxicity when administered at therapeutic and higher doses.
09/25/14
20140287479
 Modified lecithin-cholesterol acyltransferase enzymes patent thumbnailnew patent Modified lecithin-cholesterol acyltransferase enzymes
The invention provides compounds, pharmaceutical compositions and methods for treating atherosclerosis, coronary heart disease, thrombosis, and for decreasing or prevention of accumulation of cholesterol in a subject by modifying lcat polypeptide.. .
09/25/14
20140287128
 Emulsified liquid seasoning patent thumbnailnew patent Emulsified liquid seasoning
Provided is a low-calorie, low-cholesterol emulsified liquid seasoning in which syneresis, separation, and setting are suppressed. The emulsified liquid seasoning includes a crosslinked starch, an octenyl succinate-treated starch, and a polysaccharide thickener.
09/25/14
20140286945
 Enzyme inhibitor for cancer treatment patent thumbnailnew patent Enzyme inhibitor for cancer treatment
Disclosed herein is a new and improved therapy for the treatment of diseases including cancer, which comprises the step of altering cell membrane lipid composition by treating a cancer cell with an enzyme inhibitor which inhibits enzymes regulating the cholesterol biosynthetic pathway. The method may also be employed in combination with existing chemotherapeutic agents to combat the drug resistance and enhance the therapeutic efficacy of conventional therapy..
09/18/14
20140276344
 Shunting of dietary lipids including cholesterol patent thumbnailShunting of dietary lipids including cholesterol
Methods and devices for redirecting at least a portion of a fluid from the mesenteric lymphatic system for elimination from the body are disclosed. The fluid may be redirected for elimination through the urinary system or redirected outside the body.
09/18/14
20140275227
 Compositions and methods of altering cholesterol levels patent thumbnailCompositions and methods of altering cholesterol levels
The present invention relates to compositions, methods and kits using polynucleotides, primary transcripts and mmrna molecules.. .
09/18/14
20140275207
 Antisense compounds and methods of use thereof patent thumbnailAntisense compounds and methods of use thereof
Disclosed herein are compounds, compositions and methods for modulating the expression of lmw-ptpase in a cell, tissue or animal. Also provided are methods of target validation.
09/18/14
20140274946
 Method of using nutritional compounds dihydroquercetin (taxifolin) and arabinogalactan in combination with dihydroquercetin (taxifolin) to reduce and control cardiometabolic risk factors associated with metabolic syndrome and hypercholesterolemia patent thumbnailMethod of using nutritional compounds dihydroquercetin (taxifolin) and arabinogalactan in combination with dihydroquercetin (taxifolin) to reduce and control cardiometabolic risk factors associated with metabolic syndrome and hypercholesterolemia
The method of using nutritional compounds including dihydroquercetin (taxifolin). Arabinogalactan and arabinogalactan combined with dihydroquercetin (taxifolin) to reduce and control cardiometabolic risk factors, associated with metabolic syndrome and hypercholesterolemia in a mammal, specifically a human, resulting in the enhancement of metabolism, reduced control levels of cholesterol and triglycerides, reduced oxidative damage in humans and other health benefits..
09/18/14
20140273027
Serological methods and diagnostic tests for syphilis antibodies
A non-treponemal diagnostic test for syphilis infection includes initially dissolving cholesterol in an organic solvent and further diluting the dissolved cholesterol in an ethanol solution comprising cardiolipin and lecithin, permitting a volume of the antigen solution to evaporate in place within a container, rinsing the coated container with buffered saline, stabilizing the antigen coating by overcoating the antigen coating with an inert protein dissolved in buffered saline, decanting the overcoat solution, air-drying the container, and sealing the container in vapor-proof pouches with desiccant, providing an enzyme-labeled conjugate component of a syphilis infection test that is formulated to be compatible with a lipid nature of the cholesterol, the cardiolipin, and the lecithin vdrl antigens, providing a sample diluent that is formulated to be compatible with the lipid nature of the vdrl antigens, and providing a wash fluid that is formulated to be compatible with the lipid nature of the vdrl antigens.. .
09/18/14
20140272080
Spread
A spread or margarine which is intended to serve as a tasty, indulgent product and at the same time provide good health benefits to the consumer. The spread combines high levels both of monounsaturated fatty acids, which are thought to be a beneficial component of the mediterranean diet, and linoleic acid, a known ldl-cholesterol lowering moiety.
09/18/14
20140271998
Fortified egg white products
Egg products are produced which contain healthy components of egg yolks and egg whites, such as choline, lutein, omega-3 fatty acids, vitamins and minerals, but do not contain the unhealthy components of egg yolks such as cholesterol and triglycerides. The healthy yolk components or nutrients are added to egg whites to obtain a yolk-less egg product having the taste, color, and functionality of whole eggs and whole egg products.
09/18/14
20140271821
Liposomal cisplatin compositions for cancer therapy
The present invention provides a composition for the treatment of cancer including zwitterionic liposomes consisting essentially of: 50-65 mol % of a phosphatidylcholine lipid, 30-45 mol % of cholesterol, and 2-8 mol % of a peg-lipid; and cisplatin. Cisplatin is encapsulated in the liposomes in an amount such that the ratio of the total lipid weight to the cisplatin weight is from about 65:1 to about 95:1.
09/18/14
20140271820
Liposome oxaliplatin compositions for cancer therapy
The present invention provides a composition for the treatment of cancer including zwitterionic liposomes consisting essentially of: 50-70 mol % of a phosphatidylcholine lipid, 25-45 mol % of cholesterol, and 2-8 mol % of a peg-lipid; and oxaliplatin. Oxaliplatin is encapsulated in the liposomes in an amount such that the ratio of the total lipid weight to the oxaliplatin weight is from about 20:1 to about 65:1.
09/18/14
20140271815
Heat-and freeze-stable vaccines and methods of making and using same
A vaccine adjuvant composition comprising: a lipid selected from the group consisting of: dipalmitoyl phosphatidlcholine (dppc), dipalmitoyl phosphatidylglycerol (dppg), dioleoyl phosphatidylcholine (dopc), and cholesterol and containing a positively or negatively charged lipid with associated/entrapped protein antigen.. .
09/18/14
20140271796
Oxybutynin-containing transdermal absorption preparation
A transdermal absorption preparation containing at least one drug selected from oxybutynin and pharmaceutically acceptable salts thereof and 0.05% by mass or more of a sterol selected from cholesterols, cholesterol derivatives and cholesterol analogs, relative to a total amount of the transdermal absorption preparation.. .
09/11/14
20140255959
Cholesterol oxidase mutants, compositions, devices, kits and uses thereof
Compositions, devices, kits and methods are disclosed for assaying cholesterol with a cholesterol oxidase mutant that has been modified at an amino acid residue involved in the active site. The cholesterol oxidase mutant has reduced oxidase activity while substantially maintaining its dehydrogenase activity..
09/11/14
20140255539
Nutritional compositions containing structured fat globules and uses thereof
The present disclosure relates to a lipid source for nutritional compositions, comprising an enriched lipid fraction which comprises structured fat globules. The enriched lipid fraction provides fat globules having a desired size and fatty acid composition and may be stabilized by components such as phospholipids, cholesterol, milk-fat globule membrane protein and combinations thereof.
09/11/14
20140255538
Nutritional compositions containing structured fat globules and uses thereof
The present disclosure relates to a lipid source for nutritional compositions, comprising an enriched lipid fraction which comprises structured fat globules. The enriched lipid fraction provides fat globules having a desired size and fatty acid composition and may be stabilized by components such as phospholipids, cholesterol, milk-fat globule membrane protein and combinations thereof.
09/11/14
20140255537
Nutritional compositions containing an enriched lipid fraction and uses thereof
The present disclosure relates to a nutritional composition comprising a fat source that includes an enriched lipid fraction derived from milk. The enriched lipid fraction may contain saturated fatty acids, trans-fatty acids, monounsaturated fatty acids, clas, bcfas, cholesterol, milk fat globule membrane proteins, gangliosides, and mixtures thereof.
09/11/14
20140255317
Preparation comprising hexose-6-phosphate-modified cholesterol derivative
Provided is a compound represented by the general formula (1) (where: g represents a hexose-6-phosphate residue; and l represents a divalent linker group).. .
09/04/14
20140249394
Health monitoring and diagnostic device and network-based health assessment and medical records maintenance system
A health monitoring and diagnostic device (lifestream cholesterol meter) configured as a self-contained testing and diagnostic unit in a clam-shell type case. One side of the case includes a spring-loaded finger stick and a compartment for carrying one or more packages of disposable items including a test strip, a needle for the finger stick, and an alcohol swipe.
09/04/14
20140249226
Methods of administering compositions comprising docosapentaenoic acid
The present invention relates to compositions comprising docosapentaenoic acid and methods of reducing lipid parameters, such as triglycerides, total cholesterol, low density lipoprotein (ldl) cholesterol, non-hdl cholesterol, free fatty acids, and other lipids, comprising administration of omega-3 docosapentaenoic acid.. .
09/04/14
20140249225
Methods of reducing or preventing oxidative modification of membrane polyunsaturated fatty acids
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing or preventing membrane cholesterol domain formation in a subject, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.. .
09/04/14
20140248653
Method for selecting mevalonate synthesis modulators using cells derived from human pluripotent cells
A method for selecting pharmaceutical compounds affecting mevalonate or cholesterol, having a step for putting into contact with the pharmaceutical compounds to be tested, cells of the msc type obtained by a method for producing cells of the msc type from human pluripotent cells or from induced stem cells, including a step for cultivating human pluripotent cells or induced stem cells in a culture medium having the steps of: 1) one or more growth factors selected from fgfs, hgf, pdgfs, egf, herugulins and vegfs, and 2) one or more antioxidants selected from ascorbic acid and its derivatives, vitamin e and n-acetylcysteine.. .
09/04/14
20140248391
Use of infant formula with large lipid globules
The invention relates to infant nutrition comprising large lipid globules. This infant nutrition has programming effects on the body and results in a reduced level of total blood cholesterol later in life when consuming a western style diet.
09/04/14
20140248304
Non-hemolytic llo fusion proteins and methods of utilizing same
The present invention provides recombinant proteins or peptides comprising a mutated listeriolysin o (llo) protein or fragment thereof, comprising a substitution or internal deletion of the cholesterol-binding domain or a portion thereof, fusion proteins or peptides comprising same, nucleotide molecules encoding same, and vaccine vectors comprising or encoding same. The present invention also provides methods of utilizing recombinant proteins, peptides, nucleotide molecules, and vaccine vectors of the present invention to induce an immune response to a peptide of interest..
08/21/14
20140235872
Novel low molecular weight cationic lipids for oligonucleotide delivery
The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and peg-lipids to form lipid nanoparticles with oligonucleotides. It is an object of the instant invention to provide a cationic lipid scaffold that demonstrates enhanced efficacy along with lower liver toxicity as a result of lower lipid levels in the liver.
08/21/14
20140235831
Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
08/21/14
20140235830
Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
08/21/14
20140235723
Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses
The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, alzheimer's disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, syndrome x, thrombotic disorder. Compounds and methods of the invention can also be used to modulate c reactive protein or enhance bile production in a patient.
08/21/14
20140234521
Low fat mayonnaise composition and method of producing the same
Provided are a low fat mayonnaise composition to which cellulose ether is applied, and a method of producing the same, in which the low fat mayonnaise composition includes 50 wt % or less of an emulsion with respect to the total weight of the composition, and cellulose ether and an excipient as a fat substitute. Therefore, with the mayonnaise composition, low fat mayonnaise which includes an oil and fat content of ½ or less may be produced from only a vegetable material having phase stability at various temperatures without using eggs which may lead to an allergy and may serve as a primary source of increasing cholesterol..
08/21/14
20140234403
Liposome production using isopropanol
Provided are compositions and methods for producing a lipidic film. The method comprises the steps of: (i) dissolving a lipid mix in isopropanol to form a homogeneous mix; and (ii) removing the solvent from the homogeneous mix to form a lipidic film, wherein the lipid mix comprises a lipid and cholesterol..
08/14/14
20140228557
Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
08/14/14
20140228547
Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
08/14/14
20140228545
Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
08/14/14
20140228439
Ketone compounds and compositions for cholesterol management and related uses
The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising a ketone compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing alzheimer's disease, syndrome x, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, renal disease, cancer, inflammation, and impotence.
08/14/14
20140228428
Cynara scolymus extracts for the treatment of dyslipidaemia
The present invention relates to the preparation of cynara scolymus leaf extracts, which are useful for the prevention and treatment of dyslipidaemia, in particular to increase hdl cholesterol in patients at cardiovascular risk. Said extracts are useful to normalise the lipid and carbohydrate balances and significantly increase the value of hdl cholesterol by favourably changing the ldl/hdl ratio, especially in post-infarction patients with drug-induced dyslipidaemia..
08/14/14
20140227195
Complex and contrast agent for photoimaging using the same
There is provided a gelatin-icg complex that can suppress leakage of icg included therein. The complex has a gelatin derivative including at least one of a phospholipid covalently bonded to a gelatin or a cholesterol covalently bonded to a gelatin, and indocyanine green..
08/07/14
20140221418
Hyaluronic acid based copolymers
Hyaluronic acid (ha) conjugates or crosslinked has compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof..
08/07/14
20140220114
Methods for treating niemann-pick type c disease
The present invention includes methods for treating niemann-pick type c disease through administration of inhibitors of acyl-coenzyme a:cholesterol acyltransferase 1 (acat1). Acat inhibitors are used to treat symptoms of niemann-pick type c disease and prolong survival of patients with the disease, either alone or in combination with other treatments..
08/07/14
20140220038
Lrp1 as key receptor for the transfer of sterified cholesterol from very-low-density lipoproteins (vldl) to ischaemic cardiac muscle
The invention relates to novel molecules that can modulate one of the mechanisms leading to the massive deposition of cholesterol in the cardiomyocytes and/or in the smooth muscle cells of the vascular wall, during acute myocardial infarction or other clinical situations involving ischaemia. The invention also shows that the blockage of lrp1 by means of certain agents, including a recombinant expression vector, an rnai, an antibody, a sirna etc., prevents the overaccumulation of esterified cholesterol in the cardiomyocytes and/or in the smooth muscle cells of the vascular wall exposed to ischaemia.
07/31/14
20140213502
Chemical modification of apolipoprotein mimetic peptides for the production of therapeutic agents
Hydrocarbon stapling of apolipoprotein mimetic peptides increases the helicity of the peptides, enhances their ability to promote cholesterol efflux by multiple mechanisms and makes them resistant to proteolysis. Hydrocarbon stapled amphipathic helical peptides are useful in the treatment of cardiovascular diseases and other disorders..
07/31/14
20140212528
Irvingia gabonensis to treat and prevent metabolic syndrome and reduce total cholesterol, ldl cholesterol, blood glucose, c-reactive protein, and leptin levels and increasing adiponectin levels
In one embodiment, a method is provided for lowering c-reactive protein levels in a mammal. The method comprises administering a composition containing an effective amount of irvingia gabonensis seed to a mammal to reduce c-reactive protein levels in the mammal.
07/31/14
20140212527
Irvingia gabonensis to treat and prevent metabolic syndrome and reduce total cholesterol, ldl cholesterol, blood glucose, c-reactive protein, and leptin levels and increasing adiponectin levels
In one embodiment, a method is provided for lowering c-reactive protein levels in a mammal. The method comprises administering a composition containing an effective amount of irvingia gabonensis seed to a mammal to reduce c-reactive protein levels in the mammal.
07/31/14
20140212526
Irvingia gabonensis to treat and prevent metabolic syndrome and reduce total cholesterol, ldl cholesterol, blood glucose, c-reactive protein, and leptin levels and increasing adiponectin levels
In one embodiment, a method is provided for lowering c-reactive protein levels in a mammal. The method comprises administering a composition containing an effective amount of irvingia gabonensis seed to a mammal to reduce c-reactive protein levels in the mammal.
07/31/14
20140212525
Irvingia gabonensis to treat and prevent metabolic syndrome and reduce total cholesterol, ldl cholesterol, blood glucose, c-reactive protein, and leptin levels and increasing adiponectin levels
In one embodiment, a method is provided for lowering c-reactive protein levels in a mammal. The method comprises administering a composition containing an effective amount of irvingia gabonensis seed to a mammal to reduce c-reactive protein levels in the mammal.
07/31/14
20140212524
Methods and compositions to reduce fat gain, promote weight loss in mammals
The present disclosure relates to compositions and related methods to reduce body weight, body fat, waist and hip size, plasma total cholesterol, ldl, triglycerides, blood glucose, leptin and c-reactive protein levels and increase in hdl and serotonin levels in an mammal. The lepticore® formulation disclosed, at both the low and high dosages, is helpful in the management of fat gain and its related complications.
07/31/14
20140212523
Methods and compositions to reduce fat gain, promote weight loss in mammals
The present disclosure relates to compositions and related methods to reduce body weight, body fat, waist and hip size, plasma total cholesterol, ldl, triglycerides, blood glucose, leptin and c-reactive protein levels and increase in hdl and serotonin levels in an mammal. The lepticore® formulation disclosed, at both the low and high dosages, is helpful in the management of fat gain and its related complications.
07/31/14
20140212522
Methods and compositions to reduce fat gain, promote weight loss in mammals
The present disclosure relates to compositions and related methods to reduce body weight, body fat, waist and hip size, plasma total cholesterol, ldl, triglycerides, blood glucose, leptin and c-reactive protein levels and increase in hdl and serotonin levels in an mammal. The lepticore® formulation disclosed, at both the low and high dosages, is helpful in the management of fat gain and its related complications.
07/31/14
20140212521
Methods and compositions to reduce fat gain, promote weight loss in mammals
The present disclosure relates to compositions and related methods to reduce body weight, body fat, waist and hip size, plasma total cholesterol, ldl, triglycerides, blood glucose, leptin and c-reactive protein levels and increase in hdl and serotonin levels in an mammal. The lepticore® formulation disclosed, at both the low and high dosages, is helpful in the management of fat gain and its related complications.
07/31/14
20140212477
Hemoglobin-containing liposome and method for producing same
Provided are a hemoglobin-containing liposome having a specific membrane composition which secures high encapsulation efficiency of hemoglobin and exhibits excellent physical stability and in-vivo stability; and a method for producing the hemoglobin-containing liposome. A hemoglobin-containing liposome includes a hemoglobin solution as an internal fluid of a liposome, in which the membrane of the liposome is constituted of a lipid mixture of a phospholipid, cholesterol, and a saturated higher fatty acid, and a molar ratio of the cholesterol to the phospholipid (cholesterol/phospholipid) is 0.7 to 1.0, and the content of stearic acid in the lipid mixture is 25 to 30 mol %.


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This listing is a sample listing of patent applications related to Cholesterol for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Cholesterol with additional patents listed. Browse our RSS directory or Search for other possible listings.
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