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Cholesterol patents



      
           
This page is updated frequently with new Cholesterol-related patent applications. Subscribe to the Cholesterol RSS feed to automatically get the update: related Cholesterol RSS feeds. RSS updates for this page: Cholesterol RSS RSS


Date/App# patent app List of recent Cholesterol-related patents
07/17/14
20140200217
 Smoothened antagonism for the treatment of hedgehog pathway-related disorders patent thumbnailSmoothened antagonism for the treatment of hedgehog pathway-related disorders
The invention provides methods for modulating, e.g., antagonizing, the activity of the hedgehog signaling pathway, and for treating hedgehog related disorders such as cancers (e.g., medulloblastoma). In particular, the invention provides methods for inhibiting aberrant growth states resulting from phenotypes such as ptch loss-of-function, hedgehog gain-of-function, smoothened gain-of-function or gli gain-of-function by administering to a mammal combinations of smoothened inhibitors (e.g., a compound of formula i, formula ii, or formula iii, or any of the compounds listed herein or incorporated by reference) and cholesterol biosynthesis pathway inhibitors (e.g., statins), gli inhibitors, and/or phosphatidylinositol 3-kinase (pi3k) inhibitors..
07/17/14
20140199341
 Use of antrodia camphorata for treating diseases patent thumbnailUse of antrodia camphorata for treating diseases
The present invention relates to the use of antrodia camphorata in the treatment of skin conditions, such as acne vulgaris, urticaria and eczema, allergic rhinitis, diabetes mellitus and its complications, cancer cachexia, hypercholesterolemia, gout in a subject in need of such treatment. The present invention is also directed to the use of antrodia camphorata in the prevention and treatment of oral cancer and arterial restenosis, in a subject in need of such prevention.
07/17/14
20140199296
 Cancer drug and uses patent thumbnailCancer drug and uses
A pharmaceutical composition comprising a cancer therapeutic that is capable of inhibiting and/or reducing the ability of a cancer cell to take up and utilize glucose or other energy source, a lipid or other building block of a cell membrane or organelle, and/or cholesterol. The pharmaceutical composition can comprise one or more cancer therapeutics that can be administered individually or in combination to an individual..
07/17/14
20140199270
 Methods and compositions to reduce fat gain, promote weight loss in mammals patent thumbnailMethods and compositions to reduce fat gain, promote weight loss in mammals
The present disclosure relates to compositions and related methods to reduce body weight, body fat, waist and hip size, plasma total cholesterol, ldl, triglycerides, blood glucose, leptin and c-reactive protein levels and increase in hdl and serotonin levels in an mammal. The lepticore® formulation disclosed, at both the low and high dosages, is helpful in the management of fat gain and its related complications.
07/10/14
20140194506
 Use of potassium piperonyl pentadienoate for lowering blood lipid patent thumbnailUse of potassium piperonyl pentadienoate for lowering blood lipid
The invention provides the use of potassium piperonyl pentadienoate for lowering blood lipid, including the use of the potassium piperonyl pentadienoate in the preparation of medicaments and health-care products for lowering serum total cholesterol, lowering low density lipoprotein cholesterol, lowering triglyceride as well as preventing the decrease of high density lipoprotein cholesterol.. .
07/10/14
20140194492
 Methods for treating hypercholesterolemia patent thumbnailMethods for treating hypercholesterolemia
Disclosed herein are antisense compounds and methods for decreasing ldl-c in an individual having elevated ldl-c. Additionally disclosed are antisense compounds and methods for treating, preventing, or ameliorating hypercholesterolemia and/or atherosclerosis.
07/10/14
20140194436
 Heteroarylmethyl amides patent thumbnailHeteroarylmethyl amides
Wherein a1, a2, a3 and r1 to r8 are defined in the description, and to pharmaceutically acceptable salts thereof, their manufacture, pharmaceutical compositions containing them and their use as medicaments for the treatment and/or prophylaxis of diseases which can be treated with hdl-cholesterol raising agents, such as particularly dyslipidemia, atherosclerosis and cardiovascular diseases.. .
07/10/14
20140193485
 Orally administrable liposomally encapsulated reduced glutathione, with ace inhibitors for reversal and prevention of oxidation of cholesterol and of low density lipoprotein patent thumbnailOrally administrable liposomally encapsulated reduced glutathione, with ace inhibitors for reversal and prevention of oxidation of cholesterol and of low density lipoprotein
The invention proposes the combination of reduced glutathione in a liposome (liposomal reduced glutathione) with a specified concentration of reduced glutathione within the liposome for the oral administration of a therapeutically effective amount to ameliorate the progression of vascular disease, including atherosclerosis, diabetes, hypertension, narrowing of arteries leading to decreased blood flow, ischemic events, and the formation of blood clots, abnormal platelet aggregation, and thrombotic events, by reducing the amount and effect of oxidized cholesterol, oxidized hdl and oxidized ldl. The invention also proposes combining liposomal encapsulated glutathione with ace inhibitors in order to improve the effect of lowering not only cholesterol but also the oxidized cholesterol as well as oxidized hdl and oxidized ldl.
07/03/14
20140187489
 Mucosal delivery of drugs patent thumbnailMucosal delivery of drugs
The present invention provides a composition comprising or consisting of components (a) (i) at least one mono-alkanoyl glycerol ester, wherein alkanoyl is selected from c4 to c21 alkanoyl, preferably from octanoyl and decanoyl; and (b) (i) at least one compound selected from cholesterol, phosphatidyl cholines and phosphatidyl glycerols, wherein the acyl moieties of the phosphatidyl moieties are independently selected from c6 to c21 alkanoyl and c6 to c21 alkenoyl.. .
07/03/14
20140183059
 Microfluidic devices for multiplexed electrochemical detection patent thumbnailMicrofluidic devices for multiplexed electrochemical detection
The multiplexed electrochemical microfluidic paper-based analytical device comprises multiple detection zones for the detection of multiple biochemical analytes from one single sample. Cavity valves integrated on the device will deliver the sample to different detection zones.
06/26/14
20140179900
Treatment of atherosclerosis with cholesterol ester transport protein mimotopes
The present invention relates to the use of compounds for producing a medicament for preventing and/or treating atherosclerosis, atherosclerosis risk diseases and atherosclerosis sequelae.. .
06/26/14
20140179661
N1-cyclic amine-n5-substituted biguanide derivatives, methods of preparing the same and pharmaceutical composition comprising the same
A n1-cyclic amine-n5-substituted biguanide derivative of formula 1 or a pharmaceutically acceptable salt thereof, a method of manufacturing the same, and a pharmaceutical composition including the biguanide derivative or the pharmaceutically acceptable salt thereof as an active ingredient are provided. The biguanide derivatives have an effect of inhibiting cancer cell proliferation and also exhibit anticancer activity including inhibition of cancer metastasis and cancer recurrence, because they are effective in activating ampk, which is associated with the control of energy metabolism, even when administered in a small dose compared with conventional drugs.
06/26/14
20140179660
N1-cyclic amine-n5-substituted phenyl biguanide derivatives, methods of preparing the same and pharmaceutical composition comprising the same
An n1-cyclic amine-n5-substituted phenyl biguanide derivative of formula 1 or a pharmaceutically acceptable salt thereof, a method of manufacturing the same, and a pharmaceutical composition including the biguanide derivative or the pharmaceutically acceptable salt thereof as an active ingredient are provided. The biguanide derivatives have an effect of inhibiting cancer cell proliferation and also exhibit anticancer activity including inhibition of cancer metastasis and cancer recurrence, because they are effective in activating ampk, which is associated with the control of energy metabolism, even when administered in a small dose compared with conventional drugs.
06/26/14
20140179656
Neurogenesis screening method and uses thereof
Provided herein are methods for detecting and/or confirming the neurogenesis effect of cholesterol and/or oxysterol utilizing adipose-derived stem cells (adscs). Further provided are methods of promoting neurogenesis in adscs.
06/26/14
20140178891
Diagnosis, prevention and treatment of disorders characterized by undesirable cell proliferation
The present invention relates to compositions and methods for the reduction of atherosclerotic plaques and the decrease in the level of total serum cholesterol, triglycerides, serum ldl cholesterol, and serum hdl cholesterol. The present invention also relates to methods for the diagnosis, prevention and treatment of atherosclerosis and mycoplasma associated diseases, cardiotoxicity related to cancer treatment, and chagas disease related cardiomyopathies..
06/26/14
20140178462
Amphoteric liposomes comprising neutral lipids
An amphoteric liposome comprising neutral lipids wherein said neutral lipids are selected from the group comprising cholesterol or mixtures of cholesterol and at least one neutral or zwitterionic lipid and wherein k (neutral) of said mixtures is 0.3 or less. Said amphoteric liposome may encapsulate an active agent, such as nucleic acid therapeutics.
06/26/14
20140178317
Anhydrous antisun cream comprising a non-emulsifying elastomeric organopolysiloxane, a matting agent and a non-silicone organic oil thickener
The present invention relates to an anhydrous composition in cream form, characterized in that it comprises, in a cosmetically acceptable support: (a) at least one oily phase; (b) at least one non-emulsifying elastomeric organopolysiloxane; (b) a photoprotective system capable of screening out uv radiation; (c) at least one matting agent; (d) at least one non-silicone organic thickener for the oily phase, chosen from: (1) crystalline polymers, preferably semi-crystalline polymers, (2) fatty acid esters of dextrin, (3) hydrophobic-modified polysaccharides, (4) crystalline olefin copolymers, (5) crystalline polycondensates, (6) polymers of lipophilic polyamide type, (7) lipophilic polyureas and polyurethanes, (8) block polymers, (9) cholesterol-based liquid-crystal agents and mixtures thereof; the said composition not comprising any humectant.. .
06/19/14
20140171391
Method for treating sepsis in patients with albumin, cholesterol and hdl levels above minimum thresholds
The invention relates to a method for treating sepsis in subjects who exhibit serum albumin levels, and one of total cholesterol or hdl levels, above minimum threshold values. The method involves intravenous administration of an emulsion, which contains a phospholipid, a neutral lipid, and a cholate salt..
06/19/14
20140170688
Rapid, low-sample-volume cholesterol and triglyceride assays
Reagents, assays, methods, kits, devices, and systems for rapid measurement of cholesterol and cholesterol sub-fractions from a blood sample are provided. Total cholesterol, low density lipoprotein cholesterol, and high density lipoprotein cholesterol can be measured in a single assay using kinetic measurements, under conditions in which cholesterol sub-species are converted to a detectable product at distinct rates.
06/19/14
20140170233
Natural feed mixture for breeding domesticated water birds
The invention relates to a natural feed mixture for breeding domesticated water birds, comprising a high carbohydrate containing basic component poor in methyl-donors, a component rich in carbohydrates, having hepatic insulin-sensitizing properties, hypothalamic appetite-stimulating plant parts, natural substances blocking cholesterol synthesis in the liver, and an additive for protecting the formation of non-cholesterol- mevalonate products.. .
06/19/14
20140170210
Methods for treating immunosuppression
The present invention includes methods for increasing white blood cell counts through administration of inhibitors of acyl-coenzyme a:cholesterol acyltransferase 1 (acat1). Acat inhibitors are used to treat symptoms of immunosuppression, either alone or in combination with other treatments..
06/12/14
20140163114
Trans-clomiphene metabolites and uses thereof
The present invention relates to substantially pure metabolites of irara-clomiphene. The invention is also directed to pharmaceutical compositions comprising these metabolites and their use in treating disorders including secondary hypogonadism, type 2 diabetes, elevated cholesterol, elevated triglycerides, wasting, lipodystrophy, female and male infertility, benign prostate hypertrophy, prostate cancer, breast cancer, ovarian cancer and endometrial cancer..
06/12/14
20140162376
Compositions and methods to assess the capacity of hdl to support reverse cholesterol transport
The invention provides compositions and methods for assessing the capacity of high density lipoprotein (hdl) to support reverse cholesterol transport in blood by measuring exchange if hdl-specific spin-labeled lipoprotein probes and electron paramagnetic spectroscopy. The invention also provides methods to identify individuals at risk for cardiovascular disease, to monitor the treatment of cardiovascular disease and in the development of therapies to treat cardiovascular disease.
06/12/14
20140161927
Ready to eat seafood patties, seafood balls, and seafood burgers
A ready to eat seafood patties, seafood balls, and seafood burgers system having ingredients combined in proportions substantially including: seafood; binding agent; and seasoning. The seafood is cooked to make the seafood patty.
06/12/14
20140161798
Anti-pcsk9 and methods for treating lipid and cholesterol disorders
The present invention provides compositions and methods for treating disorders of cholesterol and lipid metabolism by administration of an anti-pcsk9 antibody or a peptide inhibitor of pcsk9.. .
06/05/14
20140155475
Modified polynucleotides for treating lipase a, lysosomal acid, cholesterol esterase protein deficiency
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmrna molecules.. .
06/05/14
20140154217
Lactococcus lactis strains, and bacterial preparations thereof, for the production of bioactive peptides having anti-hypertensive and cholesterol-lowering effects in mammals; nutritional and therapeutic products produced therefrom
New lactococcus lactis strains, nrrl b-50571 and nrrl b-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides that reduce blood pressure, lower ldl-cholesterol (bad cholesterol) and present antioxidant properties for better cardiovascular health. These biologically active peptides may be produced within the food for the production of a food product, such as a functional food, or they may be produced from protein sources and subsequently added to a food as part of the formulation or as part of a food supplement or a pharmaceutical preparation..
05/29/14
20140148476
Methods for treating obesity and disorders associated with hyperlipidemia in a mammal
The disclosure relates to methods for treating hyperlipidemia in a mammal. The present disclosure also relates to methods for treating and/or controlling obesity in a mammal.
05/29/14
20140148399
Compositions and methods for treating or ameliorating obesity or for reducing diabetic hypercholesterolemia
Obesity is one of the major health concerns in the twenty-first century and is one of the leading causes of preventable death. It is a strong risk factor for type 2 diabetes.
05/29/14
20140147869
Method and kit for measuring cholesterol in low-density lipoproteins
A new measurement method by which ldl cholesterol can be measured readily and precisely is provided. The measurement method is for measuring ldl cholesterol in a sample..
05/22/14
20140142396
Health measurement systems
A device for monitoring health is disclosed. The device includes a body scale housing, a controller, one or more sensors, and a communications device.
05/22/14
20140141071
Orally administrable liposomally encapsulated reduced glutathione, with n-o enhancing compounds for reversal and prevention of oxidation of cholesterol and of low density lipoprotein
The invention proposes the sure of reduced glutathione in a liposome (liposomal reduced glutathione) for the oral administration of a therapeutically effective amount to ameliorate the progression of vascular disease, including atherosclerosis, diabetes, hypertension, narrowing of arteries leading to decreased blood flow, ischemic events, and the formation of blood clots, abnormal platelet aggregation, and thrombotic events, by reducing the amount and effect of oxidized cholesterol, oxidized hdl and oxidized ldl. The invention also proposes combining liposomal encapsulated glutathione with statin drugs to improve the effect of lowering not only cholesterol but also the oxidized cholesterol as well as oxidized hdl and oxidized ldl.
05/22/14
20140140971
Compositions comprising alkaline sphingomyelinases for use as a dietetic preparation, food supplement or pharmaceutical product and methods for using them
The invention relates to a composition which, depending on the user, may be taken as a nutritional, dietetic or strictly therapeutic preparation, comprising as its active substance alkaline sphingomyelinase which is capable of preventing or treating various pathological conditions including cancerous processes, inflammatory processes of the intestine, hypercholesterolaemia and infections with helicobacter pylori.. .
05/15/14
20140134235
Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors
The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.. .
05/08/14
20140128399
Methods and compositions for treating urinary tract infections using agents that mimic or elevate cyclic amp
Methods and compositions are provided for treating a urinary tract infection (uti). The methods involve administering to a subject in need thereof a camp elevator or agent that mimics camp, particularly a labdane diterpene such as forskolin or a derivative or analog thereof in a therapeutically effective amount to treat a uti.
05/08/14
20140127386
Vegetable oil composition containing palm mid-fraction fat and method of reducing plasma cholesterol
A method and composition for reducing the cholesterolemic effect in mammals of ingesting a blended nutritional fat composition containing a palm mid-fraction (pmf) hardstock fat combined with an unsaturated vegetable oil. The composition is solid or semi-solid at 20° c.
05/08/14
20140127349
Vegetable oil composition containing palm mid-fraction fat and method of reducing plasma cholesterol
A method and composition for reducing the cholesterolemic effect in mammals of ingesting a blended nutritional fat composition containing a palm mid-fraction (pmf) hardstock fat combined with an unsaturated vegetable oil. The composition is solid or semi-solid at 20° c.
05/08/14
20140127334
Drug compound for the control of blood glucose, blood lipids and weight
This invention provides compound health food compound containing licorice extract, which is made by alcohol-soluble and water-insoluble radix glycyrrhizae extracts and wolfberry. The compound can be used for the prevention and/or treatment of high blood sugar, high cholesterol and/or obesity.
05/08/14
20140127182
Using gnmt as a novel therapeutic or preventing agent for fatty liver related diseases
The present invention relates to a use of glycine n-methyltransferase (gnmt) in treating or preventing fatty liver related disease, such as nonalcoholic fatty liver disease (nafld) or hepatocellular carcinoma (hcc). The use of gnmt for treating or preventing fatty liver diseases is achieved by enhancing gnmt-npc2 interaction, and thus decreasing or preventing the accumulation of lipid and cholesterol in hepatic cells or tissues..
05/08/14
20140127164
Bacterial strains belonging to the genus bifidobacterium for use in the treatment of hypercholesterolaemia
Selected bacterial strains belonging to the genus bifidobacterium for use in the treatment of hypercholesterolaemia are described. In particular, a food composition or supplement product or medical device or pharmaceutical composition has said bacterial strains in association with sterols or phytosterols and/or stanols or phytostanols and/or glucomannan and/or konjac gum and/or prebiotic fibres and/or fermented red rice and/or betaglucans from oats, oat bran, barley, barley bran and/or aloe arborescens gel in lyophilized form..
05/01/14
20140120568
System and methodology for analyzing low-density lipoprotein transport within a multi-layered arterial wall
Low-density lipoprotein (ldl) transport while incorporating the thickening of the arterial wall and cholesterol lipid accumulation can be analyzed. A multi-layered model can be adopted to represent the heterogeneity using the darcy-brinkman and staverman filtration equations to describe transport within the porous layers of the wall.
05/01/14
20140120239
Dietary supplement and methods of use
One aspect of the invention provides dietary fiber compositions comprising effective amounts of glucomannan, xanthan gum, and alginate to produce a desired viscosity. The invention also provides food products comprising an effective amount of a dietary fiber composition.
04/24/14
20140113953
Targeting micrornas for metabolic disorders
Provided herein are methods and compositions for the treatment of metabolic disorders. Also provided herein are methods and compositions for the reduction of blood glucose level, the reduction of gluceoneogenesis, the improvement of insulin resistance and the reduction of plasma cholesterol level.
04/24/14
20140113948
Drug combinations and uses
The present specification discloses compositions comprising a pharmaceutical composition to reduce or maintain ldl and/or cholesterol levels in an individual and a plurality of therapeutic compounds to increase or maintain hdl levels in an individual. The present specification also discloses a treatment protocol wherein a pharmaceutical composition is administered to an individual on a schedule wherein the pharmaceutical composition is provided for a period of time and then not provided to the individual and this treatment protocol is repeated for the term of the individual's treatment..
04/24/14
20140112986
Proliposomal testosterone formulations
Novel testosterone formulations are disclosed where testosterone is incorporated into a phospholipid/cholesterol system to produce a proliposomal powder dispersion. The proliposomal powder dispersions of the invention may be formulated with pharmaceutically acceptable excipients to form pharmaceutical compositions.
04/17/14
20140107196
Anti-cancer lead molecule
Derivatives of plumbagin can be selectively cytotoxic to breast cancer cells. Derivative ‘a’ (acetyl plumbagin) has emerged as a lead molecule for testing against estrogen positive breast cancer and has shown low hepatotoxicity as well as overall lower toxicity in nude mice model.
04/17/14
20140107067
Compositions comprising dietary fat complexers and methods for their use
This invention relates to fat containing consumable food products comprising α-cyclodextrin. The food products have reduced levels of bioavailable fat but have substantially the same fat, cholesterol and caloric content as a like food without α-cyclodextrin.
04/17/14
20140107029
Methods and apparatus for creating particle derivatives of hdl with reduced lipid content
The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of hdl without substantially affecting ldl. These derivatives of hdl are particles with reduced lipid content, particularly reduced cholesterol content.
04/17/14
20140105879
Flour-based functional food
The invention relates to a functional flour-based food composition, in particular baked products, and a method for the preparation thereof. Specific substances of vegetable origin principally containing policosanols, isoflavones and vegetable statins are added to the flour, or to the dough for preparing the aforesaid baked products.
04/10/14
20140100275
Methods of administering compositions comprising docosapentaenoic acid
The present invention relates to compositions comprising docosapentaenoic acid and methods of reducing lipid parameters, such as triglycerides, total cholesterol, low density lipoprotein (ldl) cholesterol, non-hdl cholesterol, free fatty acids, and other lipids, comprising administration of omega-3 docosapentaenoic acid.. .
04/10/14
20140100274
Methods of administering compositions comprising docosapentaenoic acid
The present invention relates to compositions comprising docosapentaenoic acid and methods of reducing lipid parameters, such as triglycerides, total cholesterol, low density lipoprotein (ldl) cholesterol, non-hdl cholesterol, free fatty acids, and other lipids, comprising administration of omega-3 docosapentaenoic acid.. .
04/10/14
20140100273
Methods of administering compositions comprising docosapentaenoic acid
The present invention relates to compositions comprising docosapentaenoic acid and methods of reducing lipid parameters, such as triglycerides, total cholesterol, low density lipoprotein (ldl) cholesterol, non-hdl cholesterol, free fatty acids, and other lipids, comprising administration of omega-3 docosapentaenoic acid.. .
04/10/14
20140100272
Methods of administering compositions comprising docosapentaenoic acid
The present invention relates to compositions comprising docosapentaenoic acid and methods of reducing lipid parameters, such as triglycerides, total cholesterol, low density lipoprotein (ldl) cholesterol, non-hdl cholesterol, free fatty acids, and other lipids, comprising administration of omega-3 docosapentaenoic acid.. .
04/10/14
20140099392
Phaleria macrocarpa extract, extraction process and its use as cholesteryl ester transferase protein (cetp) inhibitor
An extract and/or herbal fraction and pharmaceutical preparation include extract of phaleria macrocarpa which for the purpose of this invention, is referred to as dlbs1449. The herbal extract according to the teaching of this invention is effectively applicable to inhibit the expression and activity of cholesteryl ester transferase protein (cetp), increase hdl cholesterol level, decrease ldl cholesterol level without raising blood pressure therefore it is further applicable in atherosclerosis therapy..
04/10/14
20140099385
Inhibition of fatty acid and cholesterol uptake by carbon monoxide (co)
An object of the present invention is to provide a composition for inhibiting fatty acid and cholesterol uptake in a living cell which is an inhibitor for fatty acid or cholesterol uptake by a living cell, comprising carbon monoxide (co) or a compound capable of releasing co in vivo.. .
04/10/14
20140099312
Methods for treating hypercholesterolemia and reducing ldl-c using antibodies to pcsk9
The present invention provides methods for treating hypercholesterolemia and reducing ldl-c. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an anti-pcsk9 antibody or antigen-binding fragment thereof..
04/03/14
20140094405
Cholesterol derivatives of inhibitors of viral fusion
The present invention relates to compounds comprising at least ten contiguous amino acids of the hr2 domain of a type 1 viral fusogenic protein of an enveloped virus, or a derivative thereof, attached at the c-terminal to cholesterol or a derivative thereof; or a pharmaceutically acceptable salt thereof which inhibit viral fusion. Thus compounds of the invention are useful to prevent or treat diseases caused by an enveloped virus..
04/03/14
20140093564
Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with simvastatin
The present invention is directed to novel pharmaceutical compositions comprising fixed dose combinations of a dipeptidyl peptidase-4 inhibitor (dpp-4 inhibitor), or a pharmaceutically acceptable salt thereof, and simvastatin, or pharmaceutically acceptable salt thereof, methods of preparing such pharmaceutical compositions, and methods of treating type 2 diabetes and hypercholesterolemia with such pharmaceutical compositions. In particular, the invention is directed to pharmaceutical compositions comprising fixed-dose combinations of sitagliptin phosphate and simvastatin..
04/03/14
20140093513
Methods of lowering proprotein conversate subtilisin/kexin type 9 (pcsk9)
The invention relates to new methods of modulating cholesterol by inhibiting proprotein convertase subtilisin/kexin type 9 (pcsk9) with fatty acid derivatives; and new methods for treating or preventing a metabolic disease comprising the administration of an effective amount of a fatty acid derivative. The present invention is also directed to fatty acid bioative derivatives and their use in the treatment of metabolic diseases..


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This listing is a sample listing of patent applications related to Cholesterol for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Cholesterol with additional patents listed. Browse our RSS directory or Search for other possible listings.
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