 Patent Application Title |
Patent App Num. |
Date |
 Levocarrimycin, pharmaceutical compositions, preparation methods and uses thereof | 20130150316 | 20130613 |
 The present invention relates to levocarrimycin, its pharmaceutical compositions, preparation methods and application. Levocarrimycin is a mixture of isovalerylspiramycin III, II and I as main components and contains some isobutyrylspiramycin III and II, butyrylspiramycin III and II, propionylspiramycin III and II, as well as acetylspiramycin III and II, among which, the content of isovalerylspiramycin III is no less than 30 wt %, the total content of isovalerylspiramycin III, II and I is no less than 60 wt %, and the content of acylspiramycin is 80-98 wt %. Specific optical rotation of said levocarrimycin is [α]D=−52°˜−57° in the solution of 0.02 g/ml chloroform at temperature of 25° C. The present invention also relates to the crystalline compound of isovalerylspiramycin III, II or I in levocarrimycin, and pharmaceutical... |
| Process | 20130109877 | 20130502 |
 The present invention provides a process for the preparation of Pd2(dba)3.CHCl3 comprising the steps of: (a) reacting a Pd(II) complex with an alkali metal halide in at least one alcohol solvent; and (b) reacting the product of step (a) with a mixture comprising dibenzylideneacetone, chloroform and an inorganic base to form Pd2(dba)3.CHCl3.
... |
| Composition with increased stress cracking resistance | 20120322932 | 20121220 |
 Provided is a molding composition comprising, based on the total weight of the composition, (A) 50.0% by weight to 99.5% by weight of at least one (co)polymer which is a homopolymer or copolymer of at least 80% by weight of methyl methacrylate, (B) 0.5% by weight to 50.0% by weight of at least one copolymer obtained by polymerization of a monomer, and (C) at least one low molecular weight (meth)acrylate (co)polymer having a solution viscosity in chloroform at 25° C. (ISO 1628—part 6) of less than or equal to 55 ml/g.
... |
| Method of selectively applying an antimicrobial coating to a medical device or device material | 20120183674 | 20120719 |
 A process for depositing nanoparticles on a surface. The process includes the steps of: providing a sol including a volatile non-aqueous liquid and nanoparticles suspended in the non-aqueous liquid; processing the sol to form a plurality of droplets; depositing the plurality of droplets on a surface; and evaporating the non-aqueous liquid from the surface leaving a residue of nanoparticles. The liquid can be selected from heptane, chloroform toluene, and hexane and mixtures thereof and the nanoparticles are desirably silver nanoparticles. The plurality of droplets may be formed by a spray process. The surface may be selected from a particular area, region, portion, or dimension of a medical device, device material, packaging material or combinations thereof. The residue of nanoparticles desirably provides antimicrobial properties.
... |
| Antipsychotic agents and standardized antipsychotic fractions from rauwolfia tetraphylla and process of their isolation | 20120184576 | 20120719 |
 The present invention relates to bioactive extracts its fractions and isolation of compound from Rauwolfia tetraphylla. The extracts and fractions are useful for the treatment of psychosis based on in-vivo validation on animal model and proportional binding affinities for dopaminergic-D2, Cholinergic (muscarinic) and Serotonergic (5HT2A) receptors for antipsychotic activity. The present invention relates to novel antipsychotic activity in the leaf alkaloids of Formula 1 and 2 named tetrahydroalstonine, 10-methoxytetrahydroalstonine, isoreserpiline, 10-derαethoxyreserpiline, 11-demethoxyreserpiline, reserpiline and α-yohimbine. The present invention also relates to processes for obtaining antipsychotic extracts as well as for the isolation of alkabids of formula 1 and 2 from the leaves of Rauwolfia tetraphylla. The present invention particularly relates to significant antipsychotic activity in the MeOH extract, ethylacetate and chloroform fractions of R. tetraphylla and... |
Subscribe to updates on this page: Chloroform RSS  |
| Two-component developer, replenishing developer, and image-forming method | 20120094225 | 20120419 |
| A two-component developer containing a cyan toner and a magnetic carrier, the cyan toner having the following characteristics: (i) when the concentration of the cyan toner in a solution of the cyan toner in chloroform is represented by Cc (mg/ml) and the absorbance of the solution at a wavelength of 712 nm is represented by A712, a relationship between Cc and A712 satisfies the relationship of 2.00<A712/Cc<8.15; (ii) the lightness L* and chroma C* of the cyan toner determined in a powder state satisfy the relationships of 25.0≦L*≦40.0 and 50.0≦C*≦60.0; and (iii) the absolute value for the triboelectric charge quantity of the cyan toner measured by a two-component method using the cyan toner and the magnetic carrier is 50 mC/kg or more and 120 mC/kg or... |
| Semiconductor nanoparticles and method for producing same | 20120074361 | 20120329 |
| Copper(II) acetate, zinc(II) acetate, and tin(IV) acetate are weighed so that the total amount of metal ions is 2.0×10−4 mol and the molar ratio of ions is Cu:Zn:Sn=2:1:1, and 2.0 cm3 of oleylamine is added to prepare a mixed solution. Apart from this, 1.0 cm3 of oleylamine is added to 2.0×10−4 mol of sulfur powder to prepare a mixed solution. These mixed solutions are separately heated at 60° C. and mixed at room temperature. The pressure in a test tube is reduced, followed by nitrogen filling. The test tube is heated at 240° C. for 30 minutes and then allowed to stand until room temperature. The resultant product is separated into a supernatant and precipitates by centrifugal separation. The separated supernatant is filtered, methanol is added... |
| Moulding compound for mouldings with high weather resistance | 20120015141 | 20120119 |
| A moulding compound comprises a copolymer (I)a), produced by polymerisation of 90-100% by weight methylmethacrylate, styrene and malic acid anhydride, and optionally 0-10% by weight additional monomers which can be copolymerised with methylmethacrylate, a (co)polymer (II)b), produced by polymerisation of 80-100% by weight methylmethacrylate and optionally 0-20% by weight additional monomers which can be copolymerised with methylmethacrylate, and has a solution viscosity in chloroform at 25° C. (ISO 1628 Part 6) of 50 to 55 ml/g, as well as c) optional conventional additives, auxiliary agents and/or fillers. The moulding compound is characterised in that the copolymer (I) has a solution viscosity in chloroform at 25° C. (ISO 1628 Part) of 55 ml/g or less. Also disclosed are mouldings produced by thermoplastic processing of the moulding compound... |
| Novel process for the preparation of esomeprazole and salts thereof | 20100324298 | 20101223 |
| A novel process for the preparation of omeprazole and its enantiomers, such as esomeprazole, as well as the preparation of related 2-(2-pyridinylmethyl-sulphinyl)-1H-benzimidazoles, including pantoprazole, lansoprazole and rabeprazole, as recemates or single enantiomers, and their alkali or alkaline salts has been developed. The novel process involves the surprising discovery that protection of the free-base benzimidazole sulfoxide (e.g. omeprazole or esomeprazole), by reaction with an alkyl, aryl or aralkyl chloroformate following oxidation of the corresponding sulfide, eliminates the need for its direct isolation. Subsequent removal of the protecting group with a solution of alkali or alkaline earth alkoxide in a C1-C4 alcohol directly provides the corresponding salt. By eliminating the need to handle the free-base benzimidazole sulfoxide, this advantageous procedure provides increased chemical yields over processes described in... |
| Photoelectric conversion device, production method thereof and imaging device | 20100308372 | 20101209 |
| wherein λL1, λL2, λM1 and λM2 are the wavelength at an absorption intensity of ½ of the maximum absorption intensity in the wavelength range of from 400 to 800 nm, each of λL1 and λL2 represents the wavelength in a chloroform solution spectrum when the photoelectric conversion material is dissolved in chloroform, and each of λM1 and λM2 represents the wavelength in a thin-film absorption spectrum of the photoelectric conversion material alone, provided that λL1<λL2 and λM1<λM2.
... |
| Flexible poly(arylene ether) composition and articles thereof | 20100276180 | 20101104 |
| A thermoplastic composition comprises poly(arylene ether) having an initial intrinsic viscosity greater than 0.25 dl/g as measured in chloroform at 25° C.; a polyolefin having a melt temperature greater than or equal to 120° C. and a melt flow rate of 0.3 to 15; a first block copolymer having a aryl alkylene content greater than or equal to 50 weight percent based on the total weight of the first block copolymer; a second block copolymer having an aryl alkylene content less than 50 weight percent based on the total weight of the second block copolymer; and a flame retardant, wherein the poly(arylene ether) is present in an amount greater than the amount of polyolefin. The composition is useful in the production of covered wire.
... |
| Two-component developer, replenishing developer, and image-forming method | 20100248126 | 20100930 |
| A two-component developer containing a magenta toner and a magnetic carrier, wherein the magenta toner has the characteristics: (i) when the concentration of the magenta toner in a solution of the magenta toner in chloroform is represented by Cm (mg/ml) and the absorbance of the solution at a wavelength of 538 nm is represented by A538, a relationship between Cm and A538 satisfies the relationship of 2.00<A538/Cm<6.55; (ii) the lightness L* and chroma C* of the cyan toner determined in a powder state satisfy the relationships of 35.0≦L*≦45.0 and 60.0≦C*≦72.0; and (iii) the absolute value for the triboelectric charge quantity of the magenta toner measured by a two-component method using the magenta toner and the magnetic carrier is 50 mC/kg or more and 120 mC/kg or... |
| Poly-beta-peptides from functionalized beta-lactam monomers and antibacterial compositions containing same | 20100222250 | 20100902 |
| Disclosed is a method of making β-polypeptides. The method includes polymerizing β-lactam-containing monomers in the presence of a base initiator and a co-initiator which is not a metal-containing molecule to yield the product β-polypeptides. Specifically disclosed are methods wherein the base initiator is potassium t-butoxide, lithium bis(trimethylsilyl)amide (LiN(TMS)2), potassium bis(trimethyl-silyl)amide, and sodium ethoxide, and the reaction is carried out in a solvent such as chloroform, dichloromethane, dimethylsulfoxide, or tetrahydrofuran.
... |
Subscribe to updates on this page: Chloroform RSS |
| Two-component developer, replenishing developer, and image-forming method | 20100203438 | 20100812 |
| A two-component developer containing a yellow toner and a magnetic carrier, wherein the yellow toner has the characteristics: (i) when the concentration of the yellow toner in a solution of the yellow toner in chloroform is represented by Cy (mg/ml) and the absorbance of the solution at a wavelength of 422 nm is represented by A422, a relationship between Cy and A422 satisfies the relationship of 6.00<A422/Cy<14.40; (ii) the lightness L* and chroma C* of the yellow toner determined in a powder state satisfy the relationships of 85.0≦L*≦95.0 and 100.0≦C*≦115.0; and (iii) the absolute value for the triboelectric charge quantity of the yellow toner measured by a two-component method using the yellow toner and the magnetic carrier is 50 mC/kg or more and 120 mC/kg or... |
| Development of a fermentative enrichment culture and two pure isolates that biotransform high concentrations of chloroform and other halomethanes | 20100184170 | 20100722 |
| Disclosed are fermentative enrichment cultures and two pure isolates there from for use in biotransformation of halomethanes. Disclosed bioaugmentation cultures are dominated by Enterobacteriaceae, and are implemented together with one or more electron donors such as corn syrup, glucose, and the like, and a corrinoid catalyst such as vitamin B12. Disclosed cultures and implementation methods can be utilized to transform single halomethanes or mixtures of halomethanes at high rates to non-toxic end products being primarily carbon monoxide, carbon dioxide, and, organic acids.
... |
| Composition with increased stress cracking resistance | 20100174022 | 20100708 |
| The mouldings obtainable from the composition are distinguished in particular by improved stress cracking resistance and are suitable in particular for coverings, finishes or films.
... |
| Process for bacterial production of polypeptides | 20100173389 | 20100708 |
| Refractile particles containing a heterologous polypeptide as an insoluble aggregate are recovered from bacterial periplasm. The process involves culturing bacterial cells so as to express nucleic acid encoding phage lysozyme and nucleic acid encoding the heterologous polypeptide under separate promoters, disrupting the cells mechanically to release the phage lysozyme so as to release refractile particles from the bacterial cellular matrix, and recovering the released refractile particles from the periplasm. Chloroform is not used in any step and the recovery step minimizes co-recovery of cellular debris with the released refractile particles.
... |
| Preparative method of dihydrocucurbitacin f-25-o-acetate and the use thereof in the manufacture of medicaments for treating cancers | 20100168451 | 20100701 |
| A method for producing dihydrocucurbitacin F-25-0-acetate consisting of the steps as followed: percolating radix hemsleyae using acetone as solvents to obtain extract; eluting the extract in silica gel column using chloroform: methanol as eluting agent (gradient) to obtain the crude; recrystallizating the crude using methanol or ethanol to obtain di-hydrocucurbitacin F-25-O-acetate (purity:>98%). And the use of dihydrocucurbitacin F-25-O-acetate in the manufacture of medicaments for treating cancers of liver, lung, stomach, larynx, prostate and leukemia.
... |
| Process for preparing enantiomerically enriched amino-alcohols | 20100168385 | 20100701 |
| (d) reducing the Cbz N-protected amino acid ester with a borohydride reducing agent in an organic solvent or mixture of organic solvents to form a Cbz N-protected amino-alcohol
... |
| Preparation of gabapentin enacarbil intermediate | 20100160666 | 20100624 |
| Allyl 1 {[(α-isobutanoyloxyethoxy)carbonyl]aminomethyl}-1-cyclohexane acetate can be prepared by combining allyl 1-aminomethyl-1-cyclohexane acetate hydrochloride, a polar organic solvent, chloroethyl chloroformate, and an amine base or an inorganic base selected from a group consisting of carbonate and bicarbonate to provide a reaction mixture; and adding isobutyric acid to the reaction mixture. The product can be purified and/or converted to gabapentin enacarbil.
... |
| Two-component developer, replenishing developer, and image-forming method | 20100159380 | 20100624 |
| A two-component developer containing a cyan toner and a magnetic carrier, wherein the cyan toner has the characteristics: (i) when the concentration of the cyan toner in a solution of the cyan toner in chloroform is represented by Cc (mg/ml) and the absorbance of the solution at a wavelength of 712 nm is represented by A712, a relationship between Cc and A712 satisfies the relationship of 2.00<A712/Cc<8.15; (ii) the lightness L* and chroma C* of the cyan toner determined in a powder state satisfy the relationships of 25.0≦L*≦40.0 and 50.0≦C*≦60.0; and (iii) the absolute value for the triboelectric charge quantity of the cyan toner measured by a two-component method using the cyan toner and the magnetic carrier is 50 mC/kg or more and 120 mC/kg or... |
| Coloured composition with increased stress cracking resistance | 20100148401 | 20100617 |
| The invention relates to a composition containing, in relation to the total weight of said composition, A) between 50.0% by weight and 99.5% by weight of at least one (meth)acrylate (co)polymer and B) between 0.5% by weight and 50.0% by weight of at least one copolymer, obtained by the polymerisation of a monomer mixture consisting of i. between 70% by weight and 92% by weight of a vinyl aromatic monomer and ii. between 8% by weight and 30% by weight of acryl nitrile or methacryl nitrile or mixtures thereof iii. between 0% by weight and 22% by weight of at least one other monomer, the composition having at 50° C. a ΔE of less than 0.15, ΔE being defined according to the relationship (1): (1) in... |
| Demulsifying and dehydrating formulations for heavy crude oils based on block copolymers bifunctionalized with amines | 20100140141 | 20100610 |
| The present invention relates to demulsifying and dehydrating formulations of heavy crude oil based block copolymers amine bifunctionalized with low polydispersities. These formulations can contain solvents whose boiling point is in the range from 35 to 200° C., preferably: dichloromethane, chloroform, toluene, xylenes, turbosine, naphtha or mixtures thereof.
... |
| Poly(arylene ether) composition and a covered conductor with flexible covering wall and large size conductor | 20100122845 | 20100520 |
| Disclosed herein is covered conductors with a normal to large conductor cross-section area (AWG 5 to AWG 24). The thickness of the coating can be, for example, 0.25 to 8.0 millimeter (mm). Also disclosed are a thermoplastic composition comprising a poly(arylene ether) having an intrinsic viscosity greater than 0.25 dl/g as measured in chloroform at 25° C., a styrenic resin, a polyolefin resin, and optionally a flame retardant, a compatibilizer, or a combination of a flame retardant and a compatibilizer. The coating comprises the thermoplastic composition described above.
... |
| Varnish compositions for electrical insulation and method of using the same | 20100119716 | 20100513 |
| A process for preparing a redistributed poly(phenylene ether), comprising reacting a poly(phenylene ether) in a reactive diluent monomer with a polyhydric phenol in the presence of a redistribution catalyst to form a composition comprising a redistributed poly(phenylene ether) in the reactive monomer diluent. The redistributed poly(phenylene ether) exhibits an intrinsic viscosity in the range of about 0.06 deciliters per gram to about 0.25 deciliters per gram, measured in chloroform at 25° C. The redistributed poly(phenylene ether) can be functionalized and admixed with unsaturated resin such as an unsaturated polyester resin or vinyl ester resin to obtain a varnish composition that, when cured, can form an electrically insulative thermoset.
... |
| Process for preparing o-chloromethylphenylglyoxylic esters, improved process for preparing (e)-2-(2-chloromethylphenyl)-2-alkoximinoacetic esters, and novel intermediates for their preparation | 20100113778 | 20100506 |
| and intermediates for their preparation.
... |
| High temperature melt processable semi-crystalline poly (aryl ether ketone) containing a (4-hydroxyphenyl) phthalazin-1 (2h)-one comonomer unit | 20100113688 | 20100506 |
| Compositions and methods for a melt processable semicrystalline poly(aryl ether ketone) incorporating phthalazinone and 4,4′-biphenol as comonomer units are described herein. The polymers are resistant to and insoluble in common organic solvents and liquids as well as in aggressive organic solvents such as chloroform and chlorinated liquids. The polymers are melt processable via techniques such as extrusion, injection molding, and compression molding. The semicrystalline poly(aryl ether ketone) containing phthalazinone comonomer units have properties which make them suitable for manufacturing high temperature resistant molded systems and other articles.
... |
| Fluorescent detection of proteins in polyacrylamide gels | 20100089753 | 20100415 |
| The mechanism of the UV light-induced reaction between the indole moiety of tryptophan and chloroform, and the structure of the modified tryptophan and polypeptides including such modified tryptophan residues. The excited indole moiety, which is formed upon UV light irradiation, emits a solvated electron which initiates a series of events that yield fluorescent derivatives that have CHO group covalently bound to the indole moiety. These derivatives are herein referred to as formyltryptophan, and are relatively stable. Similar reactions are observed when 5-hydroxytryptophan, 5-fluorotryptophan, or N-methylindolacetate are used in place of tryptophan, or when other haloalkanes, such as trichloracetic acid, trichlorethanol, trichlorethane, bromoform, and iodoactetate are used in place of chloroform. The derivatives can be used in a variety of applications in fluorescence spectroscopy, and for nuclear... |
| Process for the preparation of tauroursodesoxycholic acid | 20100069654 | 20100318 |
| The present invention relates to a novel method for preparing tauroursodeoxycholic acid which comprises a step of selective precipitation of the impurities present in the suspension obtained from the reaction of an aqueous solution of sodium taurinate with an acetonic solution of a mixed anhydride of ursodeoxycholic acid with an alkyl chloroformate.
... |
| Methods for chemical recovery of non-carrier-added radioactive tin from irradiated intermetallic ti-sb targets | 20100064853 | 20100318 |
| The invention provides a method of chemical recovery of no-carrier-added radioactive tin (NCA radiotin) from intermetallide TiSb irradiated with accelerated charged particles. An irradiated sample of TiSb can be dissolved in acidic solutions. Antimony can be removed from the solution by extraction with dibutyl ether. Titanium in the form of peroxide can be separated from tin using chromatography on strong anion-exchange resin. In another embodiment NCA radiotin can be separated from iodide solution containing titanium by extraction with benzene, toluene or chloroform. NCA radiotin can be finally purified from the remaining antimony and other impurities using chromatography on silica gel. NCA tin-117m can be obtained from this process. NCA tin-117m can be used for labeling organic compounds and biological objects to be applied in medicine for... |
| Cyan toner | 20100062355 | 20100311 |
| Provided is a cyan toner which, while being a capsule-type toner having excellent low-temperature fixability, has excellent offset resistance and charging performance and can obtain high-quality images. A cyan toner having at least a resin (a) having a polyester as a main component, a colorant, and a wax, in which glass transition temperatures (° C.) Tg(0.5) and Tg(4.0) obtained at a rate of temperature increase of 0.5° C./min or 4.0° C./min satisfy 40.0≦Tg(0.5)≦60.0 and 2.0≦Tg(4.0)−Tg(0.5)≦10.0, and wherein, when the concentration of the cyan toner in an ethyl acetate dispersion is Cc1 (mg/ml), and the light absorbance at a wavelength of 712 nm of the dispersion is A(ethyl acetate)712, A(ethyl acetate)712/Cc1<0.15 is satisfied, and wherein, when the concentration of the cyan toner in a chloroform solution is... |
| Functionalized boron nitride nanotubes | 20100051879 | 20100304 |
| A plasma treatment has been used to modify the surface of BNNTs. In one example, the surface of the BNNT has been modified using ammonia plasma to include amine functional groups. Amine functionalization allows BNNTs to be soluble in chloroform, which had not been possible previously. Further functionalization of amine-functionalized BNNTs with thiol-terminated organic molecules has also been demonstrated. Gold nanoparticles have been self-assembled at the surface of both amine- and thiol-functionalized boron nitride Nanotubes (BNNTs) in solution. This approach constitutes a basis for the preparation of highly functionalized BNNTs and for their utilization as nanoscale templates for assembly and integration with other nanoscale materials.
... |
| Continuous method for producing acyl peroxides | 20100036152 | 20100211 |
| The invention relates to a continuous method for producing acyl peroxides. According to said method, an acyl chloride, carboxylic acid anhydride or chloroformate is reacted with an organic hydroperoxide or hydrogen peroxide in at least two mixed reaction zones that are connected in series, the acyl compound, the peroxy compound and an aqueous solution of a base being supplied to the first reaction zone. The first reaction zone comprises a cycle for the two-phase reaction mixture via a heat exchanger in which the reaction mixture is cooled. The method allows the reaction to be carried out reliably and with high space-time yields.
... |
| Method to remove repetitive sequences from human dna | 20100021971 | 20100128 |
| The invention discloses an innovative method to deplete repetitive sequences from human DNA. The method comprises (a) providing a source DNA containing both unique and repetitive sequences and sonicating the source DNA to smaller fragments; (b) providing a driver DNA containing sequences complementary to the repetitive sequences of the source DNA and labeled with a non-radioactive label, (c) hybridizing the source DNA and the driver DNA in the presence of a molecule that binds the label to form a complex; (d) removing the hybridized repetitive sequences from the complex by using RNAase and electrophoresis or by incubating with a mixture of phenol, chloroform, and ethanol; and (e) recovering the remaining source DNA wherein said repetitive sequences being significantly removed.
... |
| Crystalline forms of quetiapine hemifumarate | 20100016579 | 20100121 |
| The present invention relates to novel crystalline forms of quetiapine hemifumarate, denominated quetiapine hemifumarate form II and quetiapine hemifumarate form III. These novel crystalline forms of quetiapine hemifumarate have been characterized by methods including x-ray powder diffraction (XRD), Fourier transform IR spectroscopy (FTIR), differential scanning calorimetry (DSC), and thermal gravimetric analysis (TGA). Methods for preparation of the novel crystalline quetiapine hemifumarate form II as its chloroform solvate and its dichloromethane solvate, form III as its chloroform solvate, and form I are provided.
... |
| Poly(arylene ether) composition and a covered conductor with thin wall and small size conductor | 20100012373 | 20100121 |
| A covered conductor comprising: a conductor; and a covering comprising a thermoplastic composition and the thermoplastic composition comprises: a poly(arylene ether) having an intrinsic viscosity greater than 0.25 dl/g as measured in chloroform at 25° C., a poly(alkenyl aromatic)polymer, a polyolefin resin and optionally a flame retardant and a compatibilizer, wherein the covered conductor essentially meets the performance requirement of ISO 6722, wherein the covering is disposed over the conductor, wherein the conductor has a cross section that meets as least one of following: (i) American Wire Gauge (AWG) from AWG 56 to AWG 26, (ii) a cross-section area from 0.000122 to 0.128 mm2 (corresponding to AWG 56 to AWG 26 according to ASTM B256-02); (iii) a nominal diameter from 0.0124 to 0.404 mm (corresponding to... |
| Preparation of alkoxysulfates | 20100010251 | 20100114 |
| A process for the preparation of alkoxysulfates from organic compounds containing one or more nucleophilic groups by reacting said organic compound, in a water-miscible solvent selected from the group consisting of sulfur-containing solvents such as dimethylsulfoxide (DMSO) or sulfolane, or polar solvents such as tetrahydrofuran (THF), dimethylformamide (DMF), dimethylacetamide (DMA) and hexamethylphosphoric triamide (HMPT), with an alkylene sulfate, in a non-water-miscible solvent selected from the group consisting of chlorinated solvents such as methylene chloride, chloroform, carbon tetrachloride, trichloroethane or chlorinated aromatics, such as chlorobenzene or dichlorobenzene, and non-chlorinated aromatics, such as toluene or xylenes, in the presence of a base selected from the group consisting of hydroxides, carbonates and hydrogen carbonates of alkali metals or alkaline earth metals.
... |
| Insecticidal extract from legume plants and method of preparing the same | 20100009912 | 20100114 |
| The invention may be summarized as follows. The present invention provides insecticides comprised of naturally-occurring compounds, such as, for example, PA1b-related peptides and terpenoid saponins. The present invention also provides for identification and characterization of a synergistic insecticidal effect between peptides and saponins extracted from plants. Furthermore, simplified extraction procedures are provided that avoid the use of a chloroform defatting step or a column chromatography step.
... |
| Methods of dispersing carbon nanotubes | 20090317660 | 20091224 |
| A method is described for preparing carbon nanotube dispersions in organic solvents such as chloroform and methyl ethyl ketone. Structures resulting from organic dispersions are also disclosed. The dispersing agents used in this method comprise long chain hydrocarbons, halogen-substituted hydrocarbons, fluorocarbons, or a mixture of hydrocarbons, halogen-substituted hydrocarbons, and fluorocarbons; wherein the hydrocarbons, halogen-substituted hydrocarbons and fluorocarbons have from 6 to 40 carbons in a chain, at least one alkene or alkyne moiety, and at least one pendant carboxylic acid, phosphonic acid, and/or sulfonic acid group or an ester of these acids.
... |
| Microwave synthesis of metal-carbon nanotube composites | 20090304923 | 20091210 |
| The present disclosure provides for improved soluble carbon nanotube (“CNT”) composites at least partially coated with a metal material, and improved methods for the synthesis, generation or formation of substantially soluble carbon nanotube composites via heating conditions (e.g., microwave reactions). For example, the present disclosure provides for methods for the rapid, controllable, environmentally-friendly formation of substantially soluble carbon nanotube composites via in-situ microwave-assisted reactions, wherein the carbon nanotube composites are at least partially coated with nanometal particles (e.g., nanoplatinum particles), and wherein the nanocomposites are substantially soluble in water and/or in organic solvents (e.g., o-dichlorobenzene (ODCB), chloroform, tetrahydrofuran (THF), ethanol, toluene, hexane and DMF).
... |
| Method for suspension polymerization of polyvinyl chloride with the creation of a catalyst directly in the reactor and stabilizing-suspending agent added thereto for said reaction | 20090292091 | 20091126 |
| Production method of polyvinyl chloride in an agitated reactor under pressure, including polymerization of vinyl monomers in aqueous suspension, of the type in which at least one vinyl monomer in aqueous solution is introduced into a reactor under agitation, having the following steps: a)—adding a stabilizing-suspending agent in hydroalcoholic suspension of an inorganic mineral powder containing at least magnesium and hydroxyl groups to said reactor, b)—adding to said reactor b1) a base; b2) a peroxide compound; b3) a chloroformate; and b4) an organic acid anhydride whereupon the separate addition of b1), b2), b3), b4), to form the reaction catalyst in situ is only and exclusively in said reactor in order to create said catalyst progressively and under the control of the addition of said stabilizing-suspending agent... |
| Varnish compositions for electrical insulation and method of using the same | 20090269488 | 20091029 |
| A varnish composition for producing an electrically insulative thermoset coating is disclosed. The varnish composition includes a functionalized poly(phenylene ether) having at least one aliphatic unsaturated group and exhibiting an intrinsic viscosity in the range of about 0.06 to about 0.25 deciliter per gram, measured in chloroform at 25° C. The varnish composition further includes an unsaturated polyester resin or vinyl ester resin, a reactive liquid monomer, and a compatibilizing agent. When cured, the polymers and reactive liquid monomer form an electrically insulative thermoset.
... |
| Varnish compositions for electrical insulation and method of using the same | 20090269488 | 20091029 |
| A varnish composition for producing an electrically insulative thermoset coating is disclosed. The varnish composition includes a functionalized poly(phenylene ether) having at least one aliphatic unsaturated group and exhibiting an intrinsic viscosity in the range of about 0.06 to about 0.25 deciliter per gram, measured in chloroform at 25° C. The varnish composition further includes an unsaturated polyester resin or vinyl ester resin, a reactive liquid monomer, and a compatibilizing agent. When cured, the polymers and reactive liquid monomer form an electrically insulative thermoset.
... |
| Process for the preparation of polycarbonates and diaryl carbonate | 20090240021 | 20090924 |
| The present invention relates to a process for the continuous preparation of polycarbonates or diaryl carbonates by the method of the phase boundary process, in which both the mixing of the organic and aqueous phase and the upstream oligomerization step or aryl chloroformate and/or diaryl carbonate preparation step are effected in a special pump.
... |
| Thermoplastic transparent composition having ability to absorb light with wavelength of 410 nm and molded body thereof | 20090208755 | 20090820 |
| The present invention provides a thermoplastic transparent composition comprising: (A) 100 parts by mass of a transparent thermoplastic resin; and (B) 0.3 to 3.0 parts by mass of an ultraviolet absorber having an absorption band in the range at least of 340 to 410 nm, when determined in a chloroform solution, and also provides a molded article of the same. The thermoplastic transparent composition of the present invention has excellent transparency and shuts off light of 410 nm in wavelength. It can be widely used in the fields of optics, electrics, electronics, medical materials and others. For example, it can be formed into a lighting apparatus cover to provide a lighting apparatus having excellent mothproof property.
... |
| Thermoplastic transparent composition having ability to absorb light with wavelength of 410 nm and molded body thereof | 20090208755 | 20090820 |
| The present invention provides a thermoplastic transparent composition comprising: (A) 100 parts by mass of a transparent thermoplastic resin; and (B) 0.3 to 3.0 parts by mass of an ultraviolet absorber having an absorption band in the range at least of 340 to 410 nm, when determined in a chloroform solution, and also provides a molded article of the same. The thermoplastic transparent composition of the present invention has excellent transparency and shuts off light of 410 nm in wavelength. It can be widely used in the fields of optics, electrics, electronics, medical materials and others. For example, it can be formed into a lighting apparatus cover to provide a lighting apparatus having excellent mothproof property.
... |
| Process for the preparation of amorphous calcium salt of atorvastatin | 20090182030 | 20090716 |
| A process for the preparation of amorphous atorvastatin calcium. The process includes providing a reaction mixture having a pH between 6.5 and 8.0 containing a sodium salt of atorvastatin and tetrahydrofuran. A non-cyclic chlorinated organic solvent selected from the group consisting of dichloromethane, trichloroethane, tetrachloroethane and chloroform or addition of cyclic hydrocarbon solvent selected from the group consisting of cyclohexane, cyclopentane and methyl cyclohexane is added to provide a mixture of organic solvents. An equivalent or an excess quantity of a source of calcium ions selected from the group consisting of calcium acetate and calcium chloride is added. Amorphous atorvastatin calcium is isolated from an organic phase comprising the mixture of organic solvents.
... |
| Process to extract quassinoids | 20090171102 | 20090702 |
| A means for the extraction and crystallization of quassinoids such as quassin and neoquassin from natural sources containing these compounds, using compounds that are Generally Recognized As Safe by the U.S. Food and Drug Administration is provided. In particular, a means for extraction that does not require use of lead acetate, chloroform, methanol, or diethyl ether is provided. The process includes a means of removing non-polar and very polar substances from an extracted residue to enhance crystallization of quassinoids from the residue.
... |
| Process for the preparation of an anti microbial extract from leaves of the plant callistemon rigidus | 20090163526 | 20090625 |
| A process for the preparation of an antimicrobial extract from leaves of the plant Callistemon rigidus by cold extract using organic solvents selected from methanol, ethanol, chloroform, dichlorom ethane, hexane, diethyl and ether, concentrating the filtrate in vacuo to obtain the crude extract.
... |
| Process for the preparation of an anti microbial extract from leaves of the plant callistemon rigidus | 20090163526 | 20090625 |
| A process for the preparation of an antimicrobial extract from leaves of the plant Callistemon rigidus by cold extract using organic solvents selected from methanol, ethanol, chloroform, dichlorom ethane, hexane, diethyl and ether, concentrating the filtrate in vacuo to obtain the crude extract.
... |
| Method of manufacturing (s)-n-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride (duloxetine) | 20090143600 | 20090604 |
| A method of preparation of (S)—N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine of formula (I) or its pharmaceutically acceptable salt, in which (RS)—N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine of formula (III) is reacted with an optically active acid, after which a crystallization is made of that diastereoisomer which yields, by reaction with an inorganic or organic base, (S)—N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine of formula (S)-III, which is then demethylated using alkylchloroformates, followed by a hydrolysis and optional conversion of the compound of formula (I) to its salt.
... |
| Angelicae sinensis extracts useful for treatment of cancers | 20090111870 | 20090430 |
| An acetone extract, chloroform extract or hexane extract of Angelicae sinensis and/or the active components purified therefrom, such as n-butylidenephthalide, are administered alone or in combination with one or more chemotherapy drugs and are effective in treating cancers.
... |
| Formulation of antimicrobial film, coatings and/or sprays containing portulaca oleracea extract and film prepared therefrom | 20090104289 | 20090423 |
| An antimicrobial film formulation is prepared by extracting Portulaca oleracea using chloroform, petroleum ether or hot water, filtering and concentrating the extract, processing the concentrated extract into a liquid or powder state, and completely dissolving 0.25-0.5% (w/v) of the Portulaca oleracea extract, 1.5-2% (w/v) of chitosan and 0.5-2% (w/v) of glycerol in 100% (v/v) of vinegar (containing about 3-5% acetic acid).
... |
| Method for preparing ester compounds as bleach activators | 20090105495 | 20090423 |
| A method for preparing an ester bleach activator compound is disclosed. The method includes (A) preparing fatty acid monoester; (B) making chloroformate by reacting the fatty acid monoester with at least one selected from the group consisting of phosgene, diphosgene and triphosgene in the presence of base; and (C) reacting the chloroformate with hydroxybenzene, its derivatives, or its salts in solvent. According to the method, the ester bleach activator compound can be made in a simple and economic way.
... |
| Process for the synthesis of l-(+)-ergothioneine | 20090093642 | 20090409 |
| This invention relates to a novel process for the preparation of optically pure L-(+)-ergothioneine. The process for the chemical synthesis of L-ergothioneine comprises steps which consist of reacting L-histidine alkyl ester with an acid halide, chloroformate or pyrocarbonate in the presence of a base, hydrolysis of the alkyl-(S,Z)-2,4,5-triamidopent-4-enoate to obtain a (S)-alkyl 2,5-diamido-4-oxopentanoate, acid catalyzed hydrolysis of the (S)-alkyl 2,5-diamido-4-oxopentanoate followed by reaction with a metal thiocyanate to obtain the thiohistidine, protection of the sulfur of thiohistidine as the tert-butyl thioether, dialkylation of the primary amine to obtain a tertiary amine, quaternization of the tertiary amine, and removal of the protecting group to obtain the desired (S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trialkylammonio)propanoate (I). This process affords a better yield and is capable of practical application at large scale.
... |
| Multiplexing matrix-analyte stereo electronic interactions for high throughput shotgun metabolomics | 20090065687 | 20090312 |
| A shotgun metabolomics approach using MALDI-tandem mass spectrometry was developed for the rapid analysis of cellular metabolites. Through the use of neutral organic solvents to inactivate endogenous enzyme activities (i.e., methanol/chloroform/H2O extraction), multiplexed extraction conditions and combinatorial alterations in matrix stereoelectronic composition and analyte interactions, multiple suites of metabolites were directly ionized and quantitated directly from biologic extracts without the need for prior chromatographic separation. Through combinatorial alterations in 9-aminoacridine charge, aromaticity and stacking, a set of multiplexed conditions was developed that allowed identification of many hundreds of peaks corresponding to metabolites from mouse heart extracts. Identification of metabolite peaks was based on mass accuracy and isomeric species were assigned based on diagnostic fragment ions present during tandem mass spectrometry for many of the identified metabolite... |
| Method for making polyethylene glycol carbonates | 20090054621 | 20090226 |
| A method for making a alkyl polyethylene glycol carbonate by the step of: (a) reacting mono-alkyl polyethylene glycol (MPEG) such as MPEG having an average molecular weight of 20,000 grams per mole and a polydispersity of less than 1.1, a chloroformate such as p-nitrophenyl chloroformate, an aromatic solvent such as toluene and an amine such as tripentyl amine. And, a method for making a multi-armed polyethylene glycol carbonate by the step of: (a) reacting a multi-armed polyethylene glycol having at least one hydroxyl group, a chloroformate, an aromatic solvent and an amine.
... |
| novel process for preparation of cefprozil intermediate | 20090048460 | 20090219 |
| [R-(Z)]-[4-hydroxy-α-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]] benzeneacetic acid, mono potassium salt is reacted with ethyl chloroformate to obtain mixed anhydride which is then silylated with N,O-bis(trimethylsilyl)acetamide. The silylated compound obtained is reacted with [7-trimethylsilylamino-3-(Z/E-propen-1-yl)-3-cephem-4-carboxylic acid]trimethylsilyl ester and deprotected with aqueous hydrochloric acid to give cefprozil.
... |
| Physiologically active substance nk13650p3, method of producing the same and use thereof | 20090041799 | 20090212 |
| A physiologically active substance NK13650P3 having the following physicochemical properties or a pharmacologically acceptable salt thereof. 1) Appearance: pale yellow powder 2) Molecular formula: C29H37N7O15 3) Molecular weight: 723 4) Hydrogen nuclear magnetic resonance spectrum: spectrum measured at 600 MHz in heavy water contains the following signals: chemical shift value δ ppm: 7.05(1H, 3), 7.00(1H, d), 6.96(1H, d), 6.83(1H, s), etc. 5) Carbon nuclear magnetic resonance spectrum: spectrum measured at 150 MHz in heavy water contains the following signals: chemical shift value δ ppm: 181.5(s), 181.4(s), 179.9(s), 179.2(s), 174.5(s), 174.3(s), 171.5(s), 165.4(s), etc. 6) Ultraviolet light spectrum: spectrum measured in aqueous solution contains the following UV absorption bands: λmax (MeOH): 196.5 nm, 224.5 nm, 322.5 nm 7) Solubility: highly soluble in water but insoluble in methanol,... |
| Thermoplastic resin composition having ability to absorb light with wavelength of 420 nm and molded body thereof | 20090029172 | 20090129 |
| The present invention provides a thermoplastic resin composition comprising: (A) 100 parts by mass of a transparent thermoplastic resin; (B) 0.1 to 2.0 parts by mass of an ultraviolet absorber having an absorption band in the range at least of 340 to 410 nm, when determined in a chloroform solution; and (C) 0.005 to 0.25 parts by mass of an iron oxide fine particle having a mean primary particle diameter of 10 to 80 nm, and a molded article of the same. The thermoplastic resin composition of the present invention has excellent transparency, and shuts off light of 420 nm in wavelength. It can be widely used in the fields of optical, electric and electronic appliances, medical materials and others, and, for example, if it is... |
| Method for producing self-assembled construction | 20090020221 | 20090122 |
| A liquid (14) is prepared by dissolving and dispersing poly-ε-caprolactone, polyacrylamide and fine particles in chloroform. Viscosity of the liquid (14) is adjusted. Further, a substrate (30) is produced. A frame (31) is provided such that a thickness t1 is 0.5 mm. The liquid (14) is cast onto the casting area (30a) surrounded by the frame (31). A casting film (21) is formed by moving a scraper blade (33) and leveling the surface of the cast liquid (14). A plurality of droplets are formed in a systematic arrangement in the casting film (21) through condensation on the casting film (21). The droplets are evaporated by drying to form pores. Thus, the self-assembled construction having a honeycomb structure with a thickness of 5 μm and a pore... |
| Portable analytical system for detecting organic chemicals in water | 20080289397 | 20081127 |
| A portable analytical system for detecting organic chemicals in water comprising a miniature preconcentrator and a SAW detector, the latter being characterized by a nanoporous carbon coating that provides improved response compared to prior art polymer coatings, particularly when detecting low concentrations of trihalomethane chemicals, such as chloroform and bromoform.
... |
| Method for the preparation of (s)-n-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride (duloxetine) | 20080293952 | 20081127 |
| A method of preparation of (S)—N-methyl-3-(1-naphthyloxy)-3-(2-mienyl)propylamine of Formula (I) and its pharmaceutically acceptable salts, comprising a) reaction of (RS)—N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine with optically active D-tartaric acid or an acid salt derived from D-tartaric acid forming a mixture of diastereoisomeric salts of N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine and D-tartaric acid (2:1), b) isolation of the salt (S)—N,N-dimethyl-3-(naphthyloxy)-3-(2-thienyl)propylamine/D-tartrate (2:1) from the mixture of diastereoisomeric salts in an organic solvent, water or a mixture thereof and release of (S)—N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine by action of an inorganic or organic base, c) demethylation of (S)—N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine by action of an alkylchloroformate of formula ClCOOR (R=C1-C5 alkyl, or C6-C12 aryl or alkylraryl), especially phenyl, ethyl or methyl chloroformate, and d) hydrolytic release of the duloxetine base of formula I and optionally conversion of the base to a salt with the respective... |
| Optical element | 20080285144 | 20081120 |
| An optical element includes a first liquid, a second liquid, and a container, wherein the first liquid and the second liquid substantially differ in refractive index and are immiscible, the first liquid and the second liquid are hermetically placed in the container so that an interface between the first liquid and the second liquid forms a specific shape, the shape of the interface between the first liquid and the second liquid is changed by applying a voltage between the first liquid and the second liquid through electrodes formed in the container, and the container is (1) a resin container of which an inner surface portion of a container wall has a resin phase with a fluorine atom content higher than that of an internal portion of... |
| Two-component developer, replenishing developer, and image-forming method | 20080286668 | 20081120 |
| An object of the present invention is to provide a two-component developer which can achieve a high-definition image with a smaller toner laid-on level than a conventional one, provides a color gamut comparable to that of printing, can respond to an increase in printing speed, and allows an image with a stable tinge to be formed even in long-term use. The object can be achieved by a two-component developer containing a cyan toner and a magnetic carrier, the two-component developer being characterized in that the cyan toner has the following characteristics: (i) when the concentration of the cyan toner in a solution of the cyan toner in chloroform is represented by Cc (mg/ml) and the absorbance of the solution at a wavelength of 712 nm is... |
| Novel process for preparation of cefprozil intermediate | 20080281093 | 20081113 |
| The present invention relates to a process for preparing a key intermediate of cefprozil and use of this intermediate in the preparation of cefprozil thereby avoiding impurity-causing self-acylation. [R-(Z)]-[4-hydroxy-α-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]]benzeneacetic acid, mono potassium salt is reacted with ethyl chloroformate to obtain mixed anhydride which is then silylated with N,O-bis(trimethylsilyl)acetamide. The silylated compound obtained is reacted with [7-trimethylsilylamino-3-(Z/E-propen-1-yl)-3-cephem-4-carboxylic acid]trimethylsilyl ester and deprotected with aqueous hydrochloric acid to give cefprozil.
... |
| Method for producing biomaterials from bone tissue and material used for osteoplasty and tissue engineering | 20080262632 | 20081023 |
| A method for obtaining of biomaterials for osteoplasty and tissue engineering cleans a bone of natural origin, which is sawn to plates with a thickness of 0.2 to 2.0 cm, washed twice in 0.1 M phosphate buffer at 65° C., pH 5.8-6.0, calculated as two volumetric parts of the buffer solution per one part of bone, digested in a solution of activated 0.1-0.4% papain at 65° C. for 24 hours. The plates are washed with 5 volumes of water at the temperature 40-80° C., treated with 0.4 N alkali solution at room temperature for 10-24 hours, washed with flowing water, dried, defatted in ethanol/chloroform mixtures in proportion of 1:2 and then in proportion of 2:1, decalcified in 0.4-1 N hydrochloric acid, treated with 1.5-3% hydrogen peroxide... |
| Vaccine adjuvant properties of lipsomes formed at elevated temperatures from the polar chloroform extractable lipids from mycobacterium bovis | 20080248094 | 20081009 |
| The invention relates to a liposome comprising a chloroform soluble and extractable total polar lipid of Mycobacterium spp, particularly a chloroform soluble extractable total polar lipid of Mycobacterium bovis BCG. The chloroform soluble and extractable polar lipid may comprise at least one of phosphatidylinositol (PI), phosphatidylinositol mannoside (PIM1), phosphatidylinositol dimannoside (PIM2), mono and dipalmitoylated forms of PIM1 and PIM2, phospholipid of 899 m/z, phosphatidylethanolamine and cardiolipid. The liposome may be prepared by drying chloroform soluble and extractable lipid and then hydrating said dried lipid at a temperature of 65 to 75° C. in water or phosphate buffered saline (PBS). The liposome may be used, for example, to activate dendritic cells to secrete cytokines and modulate an immune response in a mammal, or to direct an immune... |
| Spray dried compositions | 20080206349 | 20080828 |
| The invention provides a method comprising the steps of: (i) providing an emulsion of: a) an aqueous solvent, such as water, b) a carrier material dispersible or soluble in (a), said carrier material being solid at ambient temperature, and preferably being a polymer and inorganic salt or a surfactant, c) a volatile second liquid phase (for example, chloroform) which is not miscible with (a), and d) a material which is dispersible or soluble in (c) but not in (a), and, (ii) Drying the emulsion at above ambient temperature (preferably by spray drying) to simultaneously remove (a) and (c) and thereby obtain the material (b) in solid form with (d) dispersed therein.
... |
| Mass separation method of magnolol from magnoliae cortex radix | 20080188693 | 20080807 |
| The present invention related to method for the mass separation of magnolol from Magnoliae cortex or Magnoliae radix. The method comprises the steps of: 1) crushing Magnoliae cortex or Magnoliae radix, extracting the crushed material with organic solvent, adding n-hexane to the extract so as to obtain a n-hexane layer; 2) concentrating the n-hexane layer in a water bath at a temperature of 30-40 ° C. and a revolution speed of 40-200 RPM under reduced pressure so as to form a crude crystal; and 3) removing the n-hexane from the crude crystal, completely dissolving the crude crystal in chloroform, adding n-hexane to the n-hexane-containing solution, and leaving the solution to stand at room temperature so as to recrystallize the solution. In the method, a column chromatography... |
| Process for the preparation of sucralose by the chlorination of sugar with triphosgene (btc) | 20080103298 | 20080501 |
| In one embodiment of the invention a method to prepare sucralose-6-acylate through chlorinating sucrose-6-acylater by BTC in the process of sucralose preparation is disclosed. In this embodiment a Vilsmeier reagent is firstly prepared below 0° C. by dissolving BTC in DMF or in component solvent, containing DMF, toluene, dichloroethane, chloroform and carbon tetrachloride. Consequently, sucrose-6-ester was chlorinated by Vilsmeier reagent. BTC can also be dissolved in one or several organic solvent such as toluene, dichloroethane, chloroform and carbon tetrachloride, and added to a DMF solution of sucrose-6-acylate for chlorination. Sucralose was prepared through de-esterifying the obtained sucralosed 6-ester using sodium methoxide/methanol or sodium ethoxide/ethanol.
... |
| Method of controllable morphology of self-assembled monolayers on substrates | 20080075885 | 20080327 |
| Method of controlling the morphology of self-assembled monolayers (SAMS) on substrates having hydrophilic surfaces. The hydrophilic surface is exposed to a fluid having a mixture of molecules which can self-assemble on the hydrophilic surface and hydrophobic molecules for a sufficient length of time so that the molecules which can self-assemble on the hydrophilic surface form a complete self-assembled monolayer. In a particular embodiment octadecylphosphonic acid (OPA) molecules have been self-assembled on oxidized substrates including but not limited to mica, silicon, sapphire, quartz and aluminum by spin-coating a solution containing the octadecylphosphonic acid (OPA) molecules and hydrophobic molecules such as chloroform or trichloroethylene under a controlled relative humidity. Control of the morphology of OPA SAMs is affected by adjusting humidity and the duration of spin-coating. Atomic force... |
| Separation of an organic phase from a mixture comprising organic and aqueous phases by solid phase systems | 20080053911 | 20080306 |
| The present invention relates to a method for separation of a mixture comprising an organic and an aqueous phase making use of a solid phase system. Still further the invention refers to a specific solid phase system, namely a spin column which can be used in order to carry out said method in an easy way. According to preferred embodiments the organic phase is phenol or phenol/chloroform.
... |
| Compound extracted from husk and fruit stem of xanthoceras sobifolia and its extracting method and use thereof | 20080058273 | 20080306 |
| A method on its extraction: grinding the husk and fruit stem of Xanthoceras Sobifolia into particles, extracting the particles with solvents, filtrating, reclaiming the solvent and collecting the concentrated solution, passing the collection through macroporous resin, eluting it by solvent, reclaiming the solvent to get the enriched solution, drying the solution to form a brown solid which called total saponins; then dissolving the total saponins in water, extracting by normal butyl alcohol, having the extraction dried to obtain brown powder, chromatographing the powder resolved solution by silica gel column repeatedly, receipting the gradient elution with 100:(35˜60) chloroform:methanol, reclaiming the eluted solution, refining and re-crystallize the left solution, will obtain the white raphide which is the invention compound—Xanthoceraside. It is verified that the compound can be used... |
| Novel process for the preparation of esomeprazole and salts thereof | 20070287839 | 20071213 |
| A novel process for the preparation of omeprazole and its enantiomers, such as esomeprazole, as well as the preparation of related 2-(2-pyridinylmethyl-sulphinyl)-1H-benzimidazoles, including pantoprazole, lansoprazole and rabeprazole, as recemates or single enantiomers, and their alkali or alkaline salts has been developed. The novel process involves the surprising discovery that protection of the free-base benzimidazole sulfoxide (e.g. omeprazole or esomeprazole), by reaction with an alkyl, aryl or aralkyl chloroformate following oxidation of the corresponding sulfide, eliminates the need for its direct isolation. Subsequent removal of the protecting group with a solution of alkali or alkaline earth alkoxide in a C1-C4 alcohol directly provides the corresponding salt. By eliminating the need to handle the free-base benzimidazole sulfoxide, this advantageous procedure provides increased chemical yields over processes described in... |
| Provision of vascular grafts with an active principle | 20070264304 | 20071115 |
| One or more substances of the group consisting of gentamicin palmitate, gentamicin myristate, gentamicin laurate, tobramycin palmitate, tobramycin myristate, tobramycin laurate, amikacin palmitate, amikacin myristate, amikacin laurate, vancomycin palmitate, vancomycin laurate, and vancomycin myristate are suitable for providing vascular grafts with an antithrombogenically active principle. The appropriate method for providing vascular grafts with an antithrombogenically active principle particularly comprises the following steps of A immersing the graft body in an alcoholic solution or an alcoholic solution with a readily volatile solvent, such as chloroform, wherein the alcoholic solution is of a member of the group consisting of gentamicin palmitate, gentamicin myristate, gentamicin laurate, tobramycin palmitate, tobramycin myristate, tobramycin laurate, amikacin palmitate, amikacin myristate, amikacin laurate, vancomycin palmitate, and vancomycin myristate, or of spraying said solution on... |
| New process for the preparation of 4-hydroxalkylamino-2-nitro-anisoles | 20070249868 | 20071025 |
| by reaction of a 4-halogeno-3-nitro-aniline of formula (II) with a chloroalkyl-chloroformate of formula (III), alkaline ring closure of the resulting carbamate and nucleophilic replacement of the halogeno atom by a methoxy group to form a derivative of formula (IV), and finally ring opening of the resulting cyclic carbamate by treatment with methanolic alkali metal hydroxide, followed by neutralization with inorganic or organic acids, wherein the complete reaction is executed in a non-aqueous medium; as well as process for the preparation of 2-amino-4-hydroxyalkylamino-anisoles of formula (V).
... |
| Biosensor to determine potassium concentration in human blood serum | 20070227886 | 20071004 |
| The present invention relates to the development of a biosensor to determine potassium in human blood serum using dibenzo-18-crown-6 (DB18C6) as ionophore. Human blood serum contains potassium in ppm levels i.e. 137 to 200 mg/litre and sodium co exists with a 30 times higher concentration. Such a high concentration tends to interfere the selectivity towards potassium, but DB18C6 proves to have an excellent selectivity towards potassium and is highly sensitive to the lowest concentration of potassium levels present in the human blood serum. So the present invention reports the fabrication and characterization of ISFET (Ion Selective Field Effect transistor) coated with a monolayer of crown ether, dissolved in chloroform, on the gate of electrode.
... |
| Moulding compound for mouldings with high weather resistance | 20070222117 | 20070927 |
| A moulding compound comprises a copolymer (I)a), produced by polymerisation of 90-100% by weight methylmethacrylate, styrene and malic acid anhydride, and optionally 0-10% by weight additional monomers which can be copolymerised with methylmethacrylate, a (co)polymer (II)b), produced by polymerisation of 80-100% by weight methylmethacrylate and optionally 0-20% by weight additional monomers which can be copolymerised with methylmethacrylate, and has a solution viscosity in chloroform at 25° C. (ISO 1628 Part 6) of 50 to 55 ml/g, as well as c) optional conventional additives, auxiliary agents and/or fillers. The moulding compound is characterised in that the copolymer (I) has a solution viscosity in chloroform at 25° C. (ISO 1628 Part) of 55 ml/g or less. Also disclosed are mouldings produced by thermoplastic processing of the moulding compound... |
| High selectivity catalysts for the conversion of carbon tetrachloride to chloroform | 20070225530 | 20070927 |
| A process for the hydrodechlorination of carbon tetrachloride to produce chloroform utilizes a supported catalyst having a bimetallic components of platinum and iridium. The bimetallic catalyst may be promoted with small amounts of a third metal, such as tin, titanium, germanium, rhenium, silicon, lead, phosphorus, arsenic, antimony, bismuth or mixtures thereof. By-product production is decreased and duration of catalyst activity is improved by the use of the catalyst of this invention.
... |
| Use of polyalkyl (meth)acrylates in lubricating oil compositions | 20070219101 | 20070920 |
| (EN) The invention relates to the use of polyalkyl ester for reducing the temperature in a lubricating oil composition. The polyalkyl ester has a specific viscosity $g(h)sp/c of between 5 and 30 ml/g, measured in chloroform at 25° C.
... |
| Methods for the production of 3-o-deactivated-4'-monophosphoryl lipid a (3d-mla) | 20070212758 | 20070913 |
| Herein is disclosed a method for producing lipopolysaccharide (LPS), comprising: (a) growing a culture of deep rough mutant bacterial strain in a medium; (b) maintaining the culture in stationary phase for at least about 5 hr; (c) harvesting cells from the culture; and (d) extracting LPS from the cells. The method allows for the production of an LPS which can be used to produce a 3-O-deacylated monophosphoryl lipid A (3D-MLA) having at least about 20 mol % of the hexaacyl congener group. Also herein is disclosed a method of extracting lipopolysaccharide (LPS) from a culture of deep rough mutant bacterial strain cells, comprising: (a) extracting the cells with a solution consisting essentially of at least about 75 wt % of an aliphatic alcohol having from 1... |
| Glove having butyl rubber layer to provide resistance to ketone family chemicals | 20070157363 | 20070712 |
| A laminate of three layers includes a middle butyl rubber layer, whereas the inner layer and outer layer materials could be chosen from natural rubber latex, carboxylated acrylonitrile butadiene rubber latex, polychloroprene, polyisoprene, carboxylated styrene butadiene, and other synthetic elastomers. Even with one material used for both inner layer and outer layer, different formulations could be used. The resultant multilayer structure provides good resistance to ketone family chemicals such as acetone and MEK. The glove also exhibits superior or much improved resistance to solvent such as DMSO, chloroform, methanol, et al as compared to currently commercially available thin wall gloves made from natural rubber latex and carboxylated acrylonitrile butadiene synthetic rubber latex. The time elapsed before the material experiences breakthrough after exposure to a ketone family... |
| Pharmaceutical compositions | 20070154520 | 20070705 |
| having an ethylene carbonate content of 70 to 100 Mol %, an intrinsic viscosity of 0.4 to 4.0 dl/g measured in chloroform at 20° C. at a concentration of 1 g/dl and a glass transition temperature of from 5 to 50° C., degradable by surface erosion which is governed by a non-hydrolytic mechanism.
... |
| Thermal interface material (tim) with carbon nanotubes (cnt) and low thermal impedance | 20070147472 | 20070628 |
| According to embodiments of the present invention, a very thin thermal interface material (TIM) is developed, which is composed of carbon nanotubes, silicon thermal grease, and chloroform. The carbon nanotubes and chloroform comprise the filler and the silicone thermal grease comprises the matrix.
... |
| Angelicae sinensis extracts useful for treatment of cancers | 20070134351 | 20070614 |
| The invention provides an acetone extract, chloroform extract or hexane extract of Angelicae sinensis and/or the active components purified therefrom, such as n-butylidenephthalide, which are effective in treating cancers.
... |
| Methods for preparing irinotecan | 20070135471 | 20070614 |
| Methods for manufacturing 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxy-camptothecin are described comprising I. reacting a mixture of 1-chlorocarbonyl-4-piperidinopiperidine hydrochloride and 7-ethyl-10-hydroxycamptothecin in a polar aprotic solvent with a base in the presence of catalytic amounts of a N-containing cyclic organic compound having 3 to 20 carbon atoms and optionally in the presence of a water binding agent in an amount which effectively binds any water present in the above reactants and solvents; or II. reacting: (a) 7-Ethyl-10-hydroxycamptothecin in a polar aprotic solvent with phosgene, trichlormethyl-chloroformate, bis(trichloromethyl)carbonate or a alternative to phosgene and a base in the presence of catalytic amounts of a N-containing cyclic organic compound having 3 to 20 carbon atoms; and (b) subsequently with piperidinopiperidine and an amine base.
... |
| Polyfunctional poly(arylene ether) method | 20070106051 | 20070510 |
| A polyfunctional poly(arylene ether) resin may be prepared by a method that includes oxidatively copolymerizing a monohydric phenol and a polyhydric phenol in an aromatic hydrocarbon solvent in the presence of a catalyst comprising a metal ion and a nitrogen-containing ligand to form a solution comprising a polyfunctional poly(arylene ether) having an intrinsic viscosity of about 0.04 to about 0.3 deciliter per gram at 25° C. in chloroform; and contacting the polyfunctional poly(arylene ether) solution with an aqueous solution of a chelating agent to extract the metal ion from the solution; wherein the chelating agent and metal ion are present in a molar ratio of about 1.0 to about 1.5. The method reduces the formation of a dispersion during the chelation step.
... |
| Methods for chlorinating sucrose-6-ester | 20070100139 | 20070503 |
| Methods for chlorinating sucrose-6-esters to produce 1′,4,6′-trichlorosucrose-6-esters include providing a reaction mixture in a temperature-controlled vessel at a temperature less than about 65° C., the reaction mixture comprising sucrose-6-ester, a tertiary amide, and a chloroformiminium chloride salt, which forms an O-alkylformiminium chloride adduct with the hydroxyl groups of the sucrose-6-ester. The methods for chlorinating the sucrose-6-ester further include subjecting the chloroformiminium chloride salt, tertiary amide, and sucrose-6-ester reaction mixture to an elevated temperature between about 75° C. and 100° C. for a period of time sufficient to produce a chlorinated product mixture of chlorinated sucrose-6-ester products consisting essentially of 1′,4,6′-trichlorogalacto-sucrose-6-ester.
... |
| Process for the preparation of imidazo[4,5-c]-quinolin-4-amines | 20070100146 | 20070503 |
| wherein R is hydrogen, C1 to C6 alkyl, C1 to C6 alkoxy or halo, R1 and R2 are independently hydrogen, C1 to C10 alkyl, C1 to C10 alkoxy, C3 to C10 cycloalkyl, C3 to C10 alkenyl, C5 to C10 cycloalkenyl, C2 to C10 alkynyl, C6 to C20 aryl or substituted C6 to C20 aryl and n is the integer 1 or 2 by reacting the corresponding N-oxide with an aqueous solution of ammonia and a C1 to C6 alkyl, C6 to C20 aryl or substituted C6 to C20 aryl chloroformate thereby forming said compound formula (1).
... |
| Siloxane bishchloroformates | 20070093629 | 20070426 |
| A continuous method for the preparation of bischloroformates of siloxane bisphenols, said method comprising introducing into a flow reactor and contacting therein at least one siloxane bisphenol, at least one metal hydroxide, at least one metal salt, at least one solvent and phosgene to form a flowing reaction mixture having an organic phase and an aqueous phase and forming bischloroformates of siloxane bisphenols in the flowing reaction mixture.
... |
| Poly-beta-peptides from functionalized beta-lactam monomers and antibacterial compositions containing same | 20070087404 | 20070419 |
| Disclosed is a method of making β-polypeptides. The method includes polymerizing β-lactam-containing monomers in the presence of a base initiator and a co-initiator which is not a metal-containing molecule to yield the product β-polypeptides. Specifically disclosed are methods wherein the base initiator is potassium t-butoxide, lithium bis(trimethylsilyl)amide (LiN(TMS)2), potassium bis(trimethyl-silyl)amide, and sodium ethoxide, and the reaction is carried out in a solvent such as chloroform, dichloromethane, dimethylsulfoxide, or tetrahydrofuran.
... |
| Method for the detection of a cannabinoid, detection kit, and developing solvent | 20070077660 | 20070405 |
| The invention relates to a method and detection kit for the detection of a cannabinoid in a cannabis sample. The method is based on TLC and the method and kit enables everyone to avoid laborious, time consuming and expensive analytical research and determine the cannabinoid content. Good results are obtained with a developing solvent with at least 25 vol. % chloroform and at least 25 vol. % 1,2-dichloro ethane.
... |
| Catalyst for polycarbonate production and process for producing polycarbonate | 20070043199 | 20070222 |
| Provided are a catalyst for producing polycarbonate comprising a reaction product obtained by reacting (a) a catalyst carrier containing nitrogen or phosphorus with (b) a palladium compound and (c) a metal compound having a redox catalytic ability and a production process for polycarbonate, comprising a first step in which an aromatic dihydroxy compound and monovalent phenol are reacted with carbon monoxide and oxygen to produce a polycarbonate prepolymer and a second step in which the above polycarbonate prepolymer is subjected to solid state polymerization to produce polycarbonate, wherein the above catalyst is used in the first step described above. The catalyst of the present invention is readily separated from polycarbonate and can repeatedly be used, and the above catalyst makes it possible to efficiently produce polycarbonate... |
| Folate-modified cholesterol-bearing pullulan as a drug carrier | 20070042970 | 20070222 |
| Folate modified cholesterol-bearing pullulan (FA-CHP) was synthesized by the reaction of folic acid γ-2-aminoethylamide and 4-nitorophenyl chloroformate-activated cholesterol-bearing pullulan, wherein folate and pullulan are connected through a NH—CH2—CH2—NH group. Approximately 0.5-1 folates are connected per about 100 glycoside units of pullulan. Then, several combinations of FA-CHP, cholesterol-bearing pullulan (CHP) and doxorubicin (DOX) mixture were tested for cancer selective cytotoxicity. A mixture of FA-CHP, CHP and DOX of 1:4:0.02 (weight ratio) gave sharp and selective damage to cells of a human epidermoid cancer KB known as expressing a high level of folate receptor. The same mixture inhibited the growth of HuH7 cells, which is a human hepatocellular carcinoma and is unknown as a folate receptor.
... |
| Polyphenylene sulfide resin compositions | 20070021549 | 20070125 |
| A polyphenylene sulfide resin composition which comprises 100 parts by weight of a polyphenylene sulfide resin (A) and, compounded therewith, 1 to 100 parts by weight of glass fibers (B) having a single-fiber diameter of 12 μm or lager and has a crystallization temperature during cooling of 205° C. or lower. Also provided is a polyphenylene sulfide resin composition which comprises 100 parts by weight of a polyphenylene sulfide resin (A) and, compounded therewith, 1 to 100 parts by weight of glass fibers (B) having a single-fiber diameter of 10 to 12 μm, excluding 12 μm, has a crystallization temperature during cooling of 205° C. or lower and a chloroform-extractable content of 0.5 wt. % or lower, and gives a 2 mm-thick molded product which has... |
| Process for the manufacture of citalopram hydrobromide | 20060293530 | 20061228 |
| The present invention describes an improved process for the preparation of pure 1-(4′-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-phthalanecarbonitrile and its bromide salt (citalopram hydrobromide), which is a well known antidepressant. Another aspect of the invention is isolation of crystalline (4-Bromo-2-hydroxymethyl)phenyl-(4-fluorophenyl)-3-(dimethylaminopropyl)methanol (Bromodiol) and conversion of desmethylcitalopram which is formed during the cyanide exchange reaction, to citalopram by heating with a mixture of formaldehyde and formic acid in chloroform. The resulting citalopram is purified using conventionally extraction methodology.
... |
| Method for the preparation of aromatic chloroformates | 20060293535 | 20061228 |
| A method for preparing an aromatic chloroformate comprising, introducing a mixture of at least one aromatic hydroxyl compound, phosgene, at least one solvent, and at least one organic base into a flow reactor to obtain a unidirectionally flowing reaction mixture. The unidirectionally flowing reaction mixture is maintained at a temperature between about 0° C. and about 60° C. to produce a single product stream comprising an aromatic chloroformate.
... |
| Adjuvant combinations of liposomes and mycobacteriaial lipids for immunization compositions and vaccines | 20060286128 | 20061221 |
| The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldioctadecylammonium-bromide/chloride (DDA) and a lipid extract from The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from <The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from Mycobacterium bovis. The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from Mycobacterium bovis<The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from Mycobacterium bovis BCG The present invention provides a vaccine adjuvant consisting of a... |
| Pharmaceutical composition useful for the treatment of hepatocellular carcinoma | 20060280817 | 20061214 |
| The present invention relates to anticancer activity against hepatocellular carcinoma of an extract and fraction isolated from flowers of Butea monosperma. Particularly, this invention relates to anticancer activity against hepatocellular carcinoma of a composition containing markered flavonoid glycosides such as butrin and isobutrin in the range of 2 to 9% by weight, isolated from the flowers of Butea monosperma by extracting the flowers with polar solvent like ethanol, methanol, aqueous ethanol or water, removing fatty non-polar constituents by triturating the extract with solvents such as ethylene chloride, methylene chloride, chloroform or ethyl acetate, suspending the residue in water, extracting with n-butanol and freeze drying the aqueous part.
... |
| Process to extract quassinoids | 20060281808 | 20061214 |
| A means for the extraction and crystallization of quassinoids such as quassin and neoquassin from natural sources containing these compounds, using compounds that are Generally Recognized As Safe by the U.S. Food and Drug Administration is provided. In particular, a means for extraction that does not require use of lead acetate, chloroform, methanol, or diethyl ether is provided. The process includes a means of removing non-polar and very polar substances from an extracted residue to enhance crystallization of quassinoids from the residue.
... |
| Organosilicon compounds and method of manufacturing the same | 20060281890 | 20061214 |
| (wherein R is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or a phenyl group, R's may be the same or different and are individually an alkyl group having 1 or 2 carbon atoms or a phenyl group, and n is an integer of 4 to 2500).
... |
| Natural essential oil sanitary insect pest repellent and its use | 20060257441 | 20061116 |
| [Object] This invention provides a dispersion containing an insect pest repellent active substance, and an adhesive or bond, ink, resin pellets, a resin product, and a sheet or a film which can exhibit a long term repellent active effect by the particles carrying the dispersion. [Means for achieving the object] The invention also concerns with a natural essential oil having a sanitary pest repellent activity; a dispersion containing, as an active component, at least one of: a first fraction of copaiba oil given by silica gel column chromatography using hexane as an elution solvent, a second fraction given by silica gel column chromatography using a 4:4:1 mixture of hexane/chloroform/ethyl acetate as an elution solvent, and a third fraction given by fractionating the remnant of the second... |
| Process for bacterial production of polypeptides | 20060240522 | 20061026 |
| Refractile particles containing a heterologous polypeptide as an insoluble aggregate are recovered from bacterial periplasm. The process involves culturing bacterial cells so as to express nucleic acid encoding phage lysozyme and nucleic acid encoding the heterologous polypeptide under separate promoters, disrupting the cells mechanically to release the phage lysozyme so as to release retractile particles from the bacterial cellular matrix, and recovering the released retractile particles from the periplasm. Chloroform is not used in any step and the recovery step minimizes co-recovery of cellular debris with the released retractile particles.
... |
| Insecticidal extract from legume plants and method of preparing the same | 20060216367 | 20060928 |
| The invention may be summarized as follows. The present invention provides insecticides comprised of naturally-occurring compounds, such as, for example, PA1b-related peptides and terpenoid saponins. The present invention also provides for identification and characterization of a synergistic insecticidal effect between peptides and saponins extracted from plants. Furthermore, simplified extraction procedures are provided that avoid the use of a chloroform defatting step or a column chromatography step.
... |
| Anti-inflammatory and cure for ageing, alzheimer's disease on phloroglucinol derivatives | 20060205808 | 20060914 |
| The fresh seeds obtained from the fresh fruits of Garcinia subelliptica, were extracted with chloroform at room temperature. The CHCl3 extract was concentrated under reduced pressure to afford a brown residue. This residue was subjected to column chromatography (silica gel) and eluted with appropriate solvent system to give two phloroglucinol derivatives (Compounds 1 and 4). Compound 1 exhibited potent inhibitory effects on the release of β-glucuronidase and lysozyme from rat neutrophils stimulated with formyl-Met-Leu-Phe(fMLP)/cyto-chalasin B (CB). Compound 1 also exhibited potent inhibitory effect on the superoxide anion generation in rat neutrophils stimulated with fMLP/CB. Compound 4 exhibited potent inhibitory effect on NO production in lipopolysaccharide (LPS)/interferon-γ (IFN-γ)-activation in N9 cells. These Compounds may be developed as anti-inflammatory, anti-cancer agent, cure for ageing, and Alzheimer's disease treatment... |
| Resin composition and transparent shaped article | 20060199015 | 20060907 |
| A transparent shaped article comprised of a resin composition containing an alicyclic structure-containing polymer and a hindered amine compound, the hindered amine compound having (1) a 400 nm light transmittance measured by a 10 mm light path cell in a 5 wt % chloroform solution of 90% or more and (2) a molecular weight of 1500 or more. According to the present invention, it is possible to provide a transparent shaped article free from ablation and clouding of the surface of the shaped article upon exposure by short wavelength light such as that of a blue laser of a wavelength of 350 nm to 530 nm and able to keep stable transparency against exposure of short wavelength light such as that of a blue laser.
... |
| Compact water purification apparatus | 20060186026 | 20060824 |
| A compact water purification apparatus (70) for purifying water from a municipal water supply prior to a point of use has multiple water purification units (72, 74, 76, 78) that can include cartridge filters for removing such as chlorine, rust and sediment, chlorine and heavy metal, dissolved iron and hydrogen sulfide, chlorine and chloroform, lead, and sediment. Also connected in series is an ultraviolet light source (80). A bypass conduit (18) connected in parallel with the water purification units and valves (30, 32, 34) permits the water from the supply to flow directly to the point of use.
... |
| Process for the immobilization of enzymes | 20060141596 | 20060629 |
| The present invention relates to a novel process for the immobilization of the enzyme on biocompatible gold nanoparticle encapsulated free-standing membranes. The binding of the enzyme occurs through the amine groups and cysteine residues to the gold nanoparticles. The free-standing gold nanoparticle membrane was synthesized at the interface between chloroform containing bis(2-(4-aminophenoxy)ethyl)ether (DAEE) and aqueous chloroauric acid solution. The membrane is formed spontaneously by the reduction of AuCl4− ions by DAEE, this process leading to the formation of gold nanoparticles. The concomitant process of oxidation of DAEE leads to the creation of a polymeric matrix in which the gold nanoparticles are embedded. The gold nanoparticle membrane is extremely stable, robust, easily handled, malleable and can be grown over large areas and thickness by suitably varying the... |
| Flexible poly(arylene ether) composition and articles thereof | 20060135661 | 20060622 |
| A thermoplastic composition comprises poly(arylene ether) having an initial intrinsic viscosity greater than 0.25 dl/g as measured in chloroform at 25° C.; a polyolefin having a melt temperature greater than or equal to 120° C. and a melt flow rate of 0.3 to 15; a first block copolymer having a aryl alkylene content greater than or equal to 50 weight percent based on the total weight of the first block copolymer; a second block copolymer having an aryl alkylene content less than 50 weight percent based on the total weight of the second block copolymer; and a flame retardant, wherein the poly(arylene ether) is present in an amount greater than the amount of polyolefin. The composition is useful in the production of covered wire.
... |
| Polycarbonate-based resin composition for extrusion using sizing die and molded article | 20060127675 | 20060615 |
| wherein a unit of each of (Pa) and (Pb) is μmol/g; as well as a molded product produced by extrusion-molding the resin composition using a sizing die. The above polycarbonate resin composition exhibits good mechanical properties and a good moldability, and is suitable for extrusion molding using a sizing die.
... |
| Novel condensation polymers from n, n*-disubstituted disulfonamides | 20060128924 | 20060615 |
| The present invention relates to novel condensation polymers where N,N*-disubstituted disulfonamides are copolymerized with an organic acid dihalide such as dicarboxylic acid dichlorides, disulfonic acid dichlorides, bis chloroformates, diphosphoryl acid dichlorides, diphosphonyl acid dichlorides, or phosgene or with diisocyanates. The polymers obtained are thermoplastic and useful in molding and extrusion application.
... |
| Process for producing nanoparticles of paclitaxel and albumin | 20060121119 | 20060608 |
| A process for producing nanoparticles of paclitaxel and albumin having antitumor properties, by which a mixture obtained by adding paclitaxel in powder form to an aqueous solution of albumin with chloroform is subjected to high pressure homogenization treatment.
... |
| Angelicae sinensis extracts useful for treatment of cancers | 20060110469 | 20060525 |
| The invention provides an acetone extract, chloroform extract or hexane extract of Angelicae sinensis and/or the active components purified therefrom, such as n-butylidenephthalide, which are effective in treating cancers.
... |
| Resin composition, and method for producing the same | 20060106162 | 20060518 |
| A resin composition having excellent impact resistance and heat resistance, comprising a poly-3-hydroxybutyrate, and a core-shell latex rubber comprising an acrylic rubber and/or silicone-acrylic rubber copolymer as a core component and polymethyl methacrylate as a shell component, or a specific thermoplastic polyurethane, is disclosed. The resin composition satisfies the following requirements (c) and (d): (c) a crystallization temperature when heated from room temperature to 180° C. at a temperature rising rate of 80° C./min by a differential scanning calorimeter, maintained at 180° C. for 1 minute, and then cooled at a temperature lowering rate of 10° C./min is 110-170° C.; and (d) a weight average molecular weight (Mw) in terms of polystyrene conversion when a chloroform soluble component is measured with a gel permeation chromatography is... |
| Method for the preparation of aliphatic chloroformates | 20060084822 | 20060420 |
| A method for preparing an aliphatic chloroformate comprising, introducing a mixture of at least one aliphatic hydroxyl compound, phosgene, at least one solvent, and optionally at least one organic base into a flow reactor to obtain a unidirectional flowing reaction mixture. The at least one aliphatic hydroxyl compound comprises at least one aliphatic hydroxyl group. The unidirectional flowing reaction mixture is maintained at a temperature between about 0° C. and about 60° C. to produce a single product stream comprising an aliphatic chloroformate.
... |
