|| List of recent Chemist-related patents
| Copper-catalysed ligation of azides and acetylenes|
A copper catalyzed click chemistry ligation process is employed to bind azides and terminal acetylenes to provide 1,4-disubstituted 1,2,3-triazole triazoles. The process comprises contacting an organic azide and a terminal alkyne with a source of reactive cu(i) ion in human blood plasma to form by cycloaddition a 1,4-disubstituted 1,2,3-triazole.
| Method of separating carbon nanotubes|
Provided is a method of separating carbon nanotubes, the method comprising: forming first carbon nanotubes having a first functional group, forming a substrate having a second functional group, and causing the first carbon nanotubes to adhere to the substrate by a click chemistry reaction between the first functional group and the second functional group.. .
| Chemical modification motifs for mirna inhibitors and mimetics|
The present invention provides polynucleotides having chemistry patterns that provide for improved stability, potency, and/or toxicity relative to their use as mirna inhibitors or mirna mimetics. The invention further provides pharmaceutical compositions and formulations comprising the polynucleotides, and methods for treating patients having a condition associated with mirna or mrna expression..
| Method of separating amorphous iron oxides|
A method for separating amorphous iron oxides is provided. The method includes steps of sampling, filtering, dissolving and separating, analyzing the solution containing amorphous radioactive iron oxides and analyzing granules containing crystalline radioactive iron oxides.
| Metal protection layer over sin encapsulation for spin-torque mram device applications|
A magnetic thin film deposition is patterned and protected from oxidation during subsequent processes, such as bit line formation, by an oxidation-prevention encapsulation layer of sin. The sin layer is then itself protected during the processing by a metal overlayer, preferably of ta, al, tin, tan or w.
| Household appliance having a physical alteration element|
A household appliance for treating at least one item according to at least one cycle of operation includes a treating chamber for receiving the at least one item for treatment according to the at least one cycle of operation, a treating chemistry dispenser receiving a unit dose container having an electrically conductive element, a physical alteration element located proximate to the treating chemistry dispenser and operable to physically alter at least a portion of the electrically conductive element and a sensor for sensing the physical alteration.. .
| Household appliance having a physical alteration element|
A household appliance for treating at least one item according to at least one cycle of operation, includes a treating chamber for receiving the at least one item for treatment according to the at least one cycle of operation, a treating chemistry dispenser receiving a unit dose container having an optically sensible element, a physical alteration element located proximate to the treating chemistry dispenser and operable to physically alter at least a portion of the optically sensible element, and a sensor to sense the physical alteration.. .
| Household appliances and methods of control|
A household appliance having a treating chamber in which is received an article for treatment, a treating chemistry dispenser configured to receive a unit dose container for the treating chemistry, and a controller for executing at least one cycle of operation and a method of operating the household appliance to physically alter a unit dose container in conjunction with a at least one cycle of operation and sensing same.. .
| In-situ tco chamber clean|
The present invention discloses new chamber clean chemistries for low temperature, gas phase, in-situ removal of fluorine doped tin oxide (fto) films. These new in-situ cleaning chemistries will enable solar glass and low-emissivity glass manufacturers to improve the quality of fto films produced, as well as reduce costs associated manual cleaning of fto deposition systems.
| Household appliance having a physical alteration element|
A household appliance for treating at least one item according to at least one cycle of operation includes a treating chemistry dispenser receiving a unit dose container and having a door moveable between an opened position and a closed position, a piercing mechanism located proximate to the treating chemistry dispenser and having a piercer that is moveable between a non-piercing position and a piercing position where the piercer is moved to perforate a unit dose container received within the treating chemistry dispenser.. .
|5-position modified pyrimidines and their use|
The present disclosure relates to the field of nucleic acid chemistry, specifically to 5-position modified uridines as well as phosphoramidite and triphosphate derivatives thereof. The present disclosure also relates to methods of making and using the same..
|Monomers and polymers for functional polycarbonates and poly(ester-carbonates) and peg-co-polycarbonate hydrogels|
The invention generally relates to functional polymers and hydrogels. More particularly, the invention provides versatile monomers and polymers with well-defined functionalities, e.g., polycarbonates and poly(ester-carbonates), compositions thereof, and methods for making and using the same.
|Novel amphiphilic graft copolymers|
A novel amphiphilic graft copolymer is described. A process to make amphiphilic graft copolymers via grafting either poly(ethylene oxide) or polylactide side chains onto an eva platform using oxo-anion ring-opening polymerization chemistry is also described.
|Anti-angiogenic gene therapy with soluble vegf receptors -1, -2 and -3 together with paclitaxel prolongs survival of mice with human ovarian carcinoma|
Anti-angiogenic gene therapy with a combination of soluble vascular endothelial growth factors (svegfr) improves the efficacy of chemotherapy with paclitaxel for reducing ovarian cancer mean tumor volume (in cubic millimetres) as measured using magnetic resonance imaging. The study groups were: adlacz control, combination of adsvegfr-1, -2 and -3, combination of adsvegfr-1, -2, -3 and paclitaxel, bevacizumab monotherapy, paclitaxel monotherapy and carboplatin monotherapy.
|Apparatus for control of on site mixing of solid peroxide source and catalyst|
An apparatus for controlling on site generation and mixing of a two or more part chemistry, such as a peroxide source and a catalyst. In particular, the invention discloses an apparatus and dispensing method for separating solid surfaces that undergo an uncontrolled, continuous reaction when contacted with water and allows for delivery of solid reactive chemistries at the same time in a standard spray from the bottom dispensing configuration while preventing continued reaction after the dosing is complete..
|Methods, devices, and materials for metallization|
A method of making an electronic device which in one embodiment comprises providing a substrate, electrolessly depositing a barrier metal at least on portions of the substrate, and using wet chemistry such as electroless deposition to deposit a substantially gold-free wetting layer having solder wettability onto the barrier metal. An electronic device which in one embodiment comprises a metallization stack.
|Double-masking technique for increasing fabrication yield in superconducting electronics|
An improved microfabrication technique for josephson junctions in superconducting integrated circuits, based on the use of a double-layer lithographic mask for partial anodization of the side-walls and base electrode of the junctions. The top layer of the mask is a resist material, and the bottom layer is a dielectric material chosen so to maximize adhesion between the resist and the underlying superconducting layer, be etch-compatible with the underlying superconducting layer, and be insoluble in the resist and anodization processing chemistries.
|Method for monitoring and controlling the chemistry of a zld process in power plants|
A method for monitoring and controlling the chemistry of a zero liquid discharge (zld) process in power plants is described. The method identifies the principal phenomena of precipitation of calcium sulphate and calcium carbonate which can occur in such system and the principal critical sections affected by such precipitation phenomena.
|Megasonic precision cleaning of semiconductor process equipment components and parts|
Apparatuses are provided for cleaning a processing component using megasonic energy including megasonic jets in combination with selective chemistries to remove sub-micron particulate contaminants from the surfaces of the processing component that is used in cleaning semiconductor, medical, or any other processing substrates. The apparatus includes a processing chamber having a carrier element that is configured to support the processing component.
|Use of ingredient water in cleaning applications|
Systems and methods for laundry applications employ ingredient water having a defined specification. The ingredient water specification may include a maximum total dissolved solids (tds) and/or a maximum tds from water hardness ions.
|Methode pour mesurer la resistance de films|
The present invention relates to a method for measuring the effect of a force on a film. In particular, the present invention relates to a method for measuring the effect of a mechanical, hydrodynamic or physical force, for example, on the integrity of a film, for example a film made of microorganisms, foodstuffs and/or chemical substances.
|Method for manufacture and structure of multiple electrochemistries and energy gathering components within a unified structure|
A method for using an integrated battery and device structure includes using two or more stacked electrochemical cells integrated with each other formed overlying a surface of a substrate. The two or more stacked electrochemical cells include related two or more different electrochemistries with one or more devices formed using one or more sequential deposition processes.
|Improved production of anti-peptide antibodies|
Anti-peptide antibodies (apas) are extremely important tools for biomedical research. Many important techniques, such as immunoblots, elisa immunoassays, immunocytochemistry, and protein microarrays are intrinsically linked to apa function and completely dependent on apa quality.
|Pre-operative use of metabolic activation therapy|
Metabolic activation therapy (mat®) is a procedure which uses intravenous insulin pulses administered with oral glucose to deliver an insulin treatment regimen that improves the biochemistry and physiology of diabetic and non-diabetic individuals. If implemented preoperatively to patients with a history of hyperglycemia who undergo surgical and other stress inducing procedures, including those requiring hospitalization, postoperative glycemic control is improved and the insulin required during and after the operation is decreased with no increase in incidents of hypoglycemia.
|Tivozanib response prediction|
A diagnostic method for predicting whether a human tumor will be sensitive or resistant to treatment with tivozanib (av-951) is disclosed. The method is based on measurement of macrophage content in a tissue sample from a tumor.
|High level production of recombinant proteins|
The present technology relates to the fields of biochemistry, molecular biology and medicine. In particular, the present technology relates to methods and compositions for increased expression of recombinant proteins..
|Elimination of n-glycolylneuraminic acid from animal products for human use|
The application is in the field of transgenic (non-human) organisms, sialic acid chemistry, metabolism and antigenicity. More particularly, the invention is related to a method to produce neu5gc-free animals and products therefrom comprising disrupting the cmah gene and thereby reducing or eliminating neu5gc from biological material of non-humans..
|Colloidal solution of silver nanoparticles and method of it preparation|
The invention relates to colloidal solutions of silver nanoparticles and to method of it preparation and can be used in different areas, particularly in medicine, veterinary science, food industry, cosmetology, household chemistry and agrochemistry. Method includes the electrochemical dissolution of silver in the deionized water.
A process for producing an analytical aid for the detection of at least one analyte in a sample, such as a body fluid. The analytical aid includes at least one housing and at least one test element including at least one test chemistry.
|Sensing platform for quantum transduction of chemical information|
A system for determining chemistry of a molecule in a high background interfering liquid environment by application of an electronic signal at a biased metal-electrolyte interface is disclosed. One or more of a resonant exchange of energy between one or more electrons exchanged by the metal and the electrolyte and vibrating bonds of a molecular analyte, for example, may be sensed by measuring small signal conductivity of an electrochemical interface..
An electrical combination including a power tool and a battery pack. The power tool includes power tool terminals.
|Led epitaxial structure|
An led epitaxial structure includes the first layer thin film and the second layer thin film. The first layer thin film and the second layer thin film are polycrystalline aluminum nitride and single crystal aluminum nitride respectively, which have good thermal conductivity, insulation, mechanical intensity, and chemistry stability.
|Methods of forming capacitors|
A method of forming capacitors includes providing first capacitor electrodes within support material. The first capacitor electrodes contain tin and the support material contains polysilicon.
|Sortase-mediated modification of viral surface proteins|
The present invention, in some aspects, provides methods, reagents, and kits for the functionalization of proteins on the surface of viral particles, for example, of bacteriophages, using sortase-mediated transpeptidation reactions. Some aspects of this invention provide methods for the conjugation of an agent, for example, a detectable label, a binding agent, a click-chemistry handle, or a small molecule to a surface protein of a viral particle.
|Dissymmetric particles (janus particles), and method for synthesizing same by means of bipolar electrochemistry|
Dissymmetric particles also called janus particles of micron or submicron size and methods of synthesis of janus particles by bipolar electrochemistry, based on substrates of isotropic or anisotropic shape. The particles include an electrically conductive substrate having at least a chemically and/or physically modified part by deposit of a layer of electrochemically depositable material, and a non-modified part.
|Chemistry compatible coating material for advanced device on-wafer particle performance|
To manufacture a coating for an article for a semiconductor processing chamber, the article including a body of at least one of al, al2o3, or sic, and a ceramic coating on the body. The ceramic coating includes a compound comprising y2o3 in a range from about 50 mol % to about 75 mol %, zro2 in a range from about 10 mol % to about 30 mol %, and al2o3 in a range from about 10 mol % to about 30 mol %, wherein the number of nodules per inch is in a range from about 30 nodules to about 45 nodules and the porosity is in a range from about 2.5% to about 3.2%..
|Money air freshner|
A motivational air freshener that is scented, configured, and decorated to provide motivation to a user. The sight and scent of the motivational air freshener serves as an olfactory and visual reminder of monetary incentives.
|Sensor array mounted on flexible carrier|
A sensor apparatus is disclosed herein. The sensor apparatus includes a flexible carrier that is elongated along a length of the carrier.
|Electronic measurements of monolayers following homogeneous reactions of their components|
The disclosure relates to novel methods for performing a solution based assay reaction with an electroactive active moiety (eam) that subsequently forms a self-assembled monolayer (sam) utilizing the advantages of faster solution reaction kinetics, sam protected electrode and surface based electrochemistry for electronic measurement.. .
|Perfluoroether sealant compositions|
Disclosed are perfluoroethers and perfluoroether compositions useful in high temperature aerospace applications. The perfluoroethers can be adapted for use with various curing chemistries..
|Analyte sensors and methods of using same|
Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor.
|[1,3,4] oxadiazole derivative and application thereof|
The present invention belongs to the medicinal chemistry field, and specifically discloses a [1,3,4]oxadiazole derivative with the structure of general formula (i) and pharmaceutically acceptable salt thereof. The compound can be used to prepare a medicine for preventing or treating a disease of the central nervous system..
|Method of fabricating an ultra low-k dielectric self-aligned via|
Methods of fabricating ultra low-k dielectric self-aligned vias are described. In an example, a method of forming a self-aligned via (sav) in a low-k dielectric film includes forming a trench pattern in a metal nitride hardmask layer formed above a low-k dielectric film formed above a substrate.
|Systematic packaging method|
A systematic packaging method, comprises providing a package, said package operable for packaging an object; and spreading and plating one or more conductive structures on said package; wherein said spreading and plating steps are performed by the methods selected from the group consisting of physically, chemistry deposit and selectively etching.. .
|Device and method for enhanced collection and assay of chemicals with high surface area ceramic|
A method and device for enhanced capture of target analytes is disclosed. This invention relates to collection of chemicals for separations and analysis.
|Hemzem anal pile driver medical device|
The hemzem anal pile driver medical device is a nonabsorbable medical minipad made from 16 ply layered facial tissue paper. The minipad is novel in that it is employed as an anal pessary using the body's own distinct anatomy, physiology, and chemistry to remain in place, and prevent the prolapse of anatomical hemorrhoids.
|Annealing a sacrificial layer|
Methods for semiconductor processing include annealing a sacrificial material to change a characteristic of the sacrificial material. Changes may include reducing line edge roughness, changing density, changing surface chemistry, or changing a dimension of patterns of the sacrificial material.
|Interface device for bio-chip|
An interface device for bio-chip at least comprises an interface unit, said interface unit consisting of instrument interface layer, fluid channel layer and sample interface layer. The instrument interface layer has at least one instrument interface.
|Method of preparing radioisotope nanostructure with ligand-metal framework and application|
This invention relates to a method of preparing a radioisotope nanostructure having a ligand-metal framework, and a radioisotope nanostructure prepared thereby. The method of preparing the radioisotope nanostructure of the invention has a simple preparation process and can thus be applied to mass production of a radioisotope nanostructure.
|Textured surfaces to enhance nano-lubrication|
Embodiments of the present invention may provide textured surfaces to be lubricated, the texturing to enhance the effectiveness of the intended nano-lubrication. The texturing may make asperities and depressions in the surface to be lubricated.
|Automatic lung parameter estimator for measuring oxygen and carbon dioxide gas exchange|
The invention relates to a device for determining two or more respiratory parameters relating to an individual and a method for determining two or more respiratory parameters relating to an individual by means of the device. The disclosed device and method may be used in an individual suffering from pulmonary gas exchange problems relating to gas exchange of oxygen and/or carbon dioxide, e.g.
|Controlled release amine-catalyzed, michael addition-curable sulfur-containing polymer compositions|
Compositions comprising sulfur-containing polymers such as polythioethers, michael acceptors, and controlled release amine catalysts employing michael addition curing chemistries useful in aerospace sealant applications are disclosed. The compositions exhibit extended pot life and the rate of curing can be tailored for specific applications..
|Michael addition curing chemistries for sulfur-containing polymer compositions|
The use of michael addition curing chemistries in compositions comprising sulfur-containing polymers such as polythioethers and polysulfides useful in aerospace sealant applications are disclosed. Sulfur-containing adducts comprising terminal michael acceptor groups are also disclosed..
|Novel method for the selection of specific affinity binders by homogeneous noncompetitive assay|
The invention generally relates to the field of immunochemistry including antibody therapy, diagnostics, and basic research and specifically relates to the area of selecting affinity molecules such as natural antibodies, including artificial antibodies, antibody mimics, and aptamers. The invention relates particularly to a method of selecting affinity molecules using a homogeneous noncompetitive assay in a high throughput process..
|Use of a bis-maleic anhydride cross-linking agent for fixation of a cell or tissue sample|
The present disclosure relates to novel bis-maleic anhydrides and to the surprising discovery that bis-maleic anhydride cross-linking agents can be used for preservation/fixation of a cell or tissue sample. Various bis-maleic anhydride cross-linking agent scan be used in methods requiring fixation of a cell or tissue sample.
|High energy density redox flow device|
Redox flow devices are described in which at least one of the positive electrode or negative electrode-active materials is a semi-solid or is a condensed ion-storing electroactive material, and in which at least one of the electrode-active materials is transported to and from an assembly at which the electrochemical reaction occurs, producing electrical energy. The electronic conductivity of the semi-solid is increased by the addition of conductive particles to suspensions and/or via the surface modification of the solid in semi-solids (e.g., by coating the solid with a more electron conductive coating material to increase the power of the device).
|Plant genome sequence and uses thereof|
The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid molecules from plant cells, in particular, genomic dna sequences from rice plants and nucleic acid molecules that contain markers, in particular, single nucleotide polymorphism (snp) and repetitive element markers.
There is disclosed a method for the manufacture of a crosslinked superabsorbent polymer material. There is further disclosed a crosslinked superabsorbent polymer material manufactured with the method.
|Bioconjugation using bifunctional linkers|
A bifunctional linker and method of use is provided that has a spacer molecule with a functional group on one end configured to couple to the surface of a substrate and a function group on the other end that is configured couple to a biomolecule and methods of use. The preferred bifunctional linker has a poly(ethylene glycol) spacer ranging from 3 to 20 ethylene glycol units that has a silane functional group to react with a substrate and an azide functional group that can couple to a biomolecule that includes an alkyne group.
|Calibration standards for digital histocytometry|
An analytical reference for digital histochemistry is constituted of an on-slide standard used to calibrate biomarker expression in biopsy material and tissue sections. The standard consists of one or more calibration standards, which are derived from cell lines that express biomarkers, and are arranged into a calibration array.
|Cell identification with nanoparticles, compositions and methods related thereto|
The present disclosure provides a method for identifying rare or low-abundant biological entities such as hodgkin's and reed-sternberg cells, circulating tumor cells in peripheral blood, circulating fetal cells, stem cells, somatic cells, hiv-infected t cells, bacteria or viruses in water, adenoviruses, enteroviruses, hepatitis a and e, dengue, swine flu, bovine diarrhea, and protozpa/helminthes. The method uses a suite of nanoparticle-conjugated agents to mark biological targets of interest for subsequent fluorescence imaging.
|Method of forming ice-phobic coating|
The present invention relates to a method for reducing gas hydrate adhesion to the interior surface of a conduit and associated equipment transporting or processing a fluid stream in oil and gas exploration and production, petroleum refining and/or petrochemistry, by providing the conduit interior surface with a coating layer exhibiting a static contact angle of the sessile water drop on the coating layer in air higher than 75° at ambient air conditions, as measured according to astm d7334-08, wherein said coating layer comprises diamond like carbon (dlc) comprising fractions of one or more components selected from the group consisting of silicon (si), oxygen (o) and fluor (f).. .