FreshPatents.com Logo
Enter keywords:  

Track companies' patents here: Public Companies RSS Feeds | RSS Feed Home Page
Popular terms

[SEARCH]

Follow us on Twitter
twitter icon@FreshPatents

Web & Computing
Cloud Computing
Ecommerce
Search patents
Smartphone patents
Social Media patents
Video patents
Website patents
Web Server
Android patents
Copyright patents
Database patents
Programming patents
Wearable Computing
Webcam patents

Web Companies
Apple patents
Google patents
Adobe patents
Ebay patents
Oracle patents
Yahoo patents

[SEARCH]

Cells patents



      
           
This page is updated frequently with new Cells-related patent applications. Subscribe to the Cells RSS feed to automatically get the update: related Cells RSS feeds. RSS updates for this page: Cells RSS RSS


Date/App# patent app List of recent Cells-related patents
08/14/14
20140230101
 Enzymes that synthesize zingiberene patent thumbnailEnzymes that synthesize zingiberene
The invention relates to nucleic acids encoding a zingiberene synthase that enables host cells and plants to make zingiberene that is useful in fragrances and for repelling or killing insects. The invention also relates to isolated zingiberene synthases and to methods for making zingiberenes..
08/14/14
20140230098
 Polypeptides having endoglucanase activity and polynucleotides encoding same patent thumbnailPolypeptides having endoglucanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having endoglucanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140230097
 Polypeptides having xylanase activity and polynucleotides encoding same patent thumbnailPolypeptides having xylanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140230096
 Polypeptides having cellobiohydrolase activity and polynucleotides encoding same patent thumbnailPolypeptides having cellobiohydrolase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140230093
 Regulatory polynucleotides and uses thereof patent thumbnailRegulatory polynucleotides and uses thereof
The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants.
08/14/14
20140230091
 Modified plants with increased oil content patent thumbnailModified plants with increased oil content
Methods and means are provided to increase the oil content of plants, particularly oleaginous plants by preventing feedback inhibition by 18:1-coenzyme a or 18:1-acyl carrier protein of the acetyl coa-carboxylase enzyme in cells of these plants in various manners.. .
08/14/14
20140230088
 Gene silencing patent thumbnailGene silencing
The invention provides methods and compositions useful in target sequence suppression and target sequence validation. The invention provides polynucleotide constructs useful for gene silencing, as well as cells, plants and seeds comprising the polynucleotides.
08/14/14
20140230080
 Method for inducing hepatocellular variation, and production method for chimeric non-human animal having humanized liver patent thumbnailMethod for inducing hepatocellular variation, and production method for chimeric non-human animal having humanized liver
The present invention provides (1) a method for producing a non-human animal having a humanized liver, comprising transplanting human hepatic stem cells and/or hepatic progenitor cells and/or immature hepatocytes to a liver-damaged non-human animal to induce the differentiation of the cells into hepatocytes, (2) a non-human animal having a humanized liver, produced by the method, (3) a method for examining the pharmacokinetics and/or hepatotoxicity of a test substance, comprising using the animal, (4) a method for producing human hepatocytes, comprising transplanting human hepatic stem cells and/or hepatic progenitor cells and/or immature hepatocytes to a liver-damaged non-human animal to induce the differentiation of the cells into hepatocytes, and (5) a method for examining the pharmacokinetics and/or hepatotoxicity of a test substance, comprising using human hepatocytes produced by the method.. .
08/14/14
20140229987
 Interactive media guidance application with intelligent navigation and display features patent thumbnailInteractive media guidance application with intelligent navigation and display features
Methods and systems are disclosed that allow a user to efficiently navigate media selections in an interactive media guidance application and easily identify media for viewing. The disclosed methods and systems provide an environment wherein video assets are displayed according to a user preference on a mosaic page with multiple cells.
08/14/14
20140229908
 Power routing in standard cells patent thumbnailPower routing in standard cells
An integrated circuit created from a cell library of compact cells. The cell library includes cells having a metal trace routed along the boundary of the cells for carrying a power supply voltage.
08/14/14
20140229905
System and method of circuit layout for multiple cells
A circuit layout method comprises inputting layout data into a circuit layout system. The layout data represents a plurality of patterns in a plurality of cells.
08/14/14
20140229813
System and method for a spreadsheet application supporting diverse formulaic functions
A spreadsheet application or other application supporting formulaic cells that automatically provides support for a number of diverse formulaic functions. The automatically provided diverse formulaic functions include a function returning the value of the formula logic if the logic can be evaluated without an error.
08/14/14
20140229673
Scheduling of reactive i/o operations in a storage environment
A system and method for effectively scheduling read and write operations among a plurality of solid-state storage devices. A computer system comprises client computers and data storage arrays coupled to one another via a network.
08/14/14
20140229664
Preloading data into a flash storage device
Programmer's data that is transferred from a programming device to a storage device is initially stored in a memory device of the storage device by using a durable data-retention storage setup. After the storage device is embedded in a host device, the programmer's data is internally (i.e., in the storage device) read from the memory device and rewritten into the memory device by using a conventional storage setup.
08/14/14
20140229663
Selectively programming data in multi-level cell memory
Devices, systems, methods, and other embodiments associated with accessing memory are described. In one embodiment, a method detects that a power quality associated with a volatile memory in a computing device meets a threshold value and in response thereto, reprogramming data from the volatile memory to a flash memory comprising multi-level cells.
08/14/14
20140229654
Garbage collection with demotion of valid data to a lower memory tier
Method and apparatus for managing data in a memory. In accordance with some embodiments, a first tier of a multi-tier memory structure is arranged into a plurality of garbage collection units (gcus).
08/14/14
20140229115
Methods for diagnosing diseases and evaluating treatments therefor using pet
The present invention relates to methods for determining whether a mammal has a disease, such as diabetes, using pet data analysis techniques. These methods include administering to a mammal a pet-compatible tracer, such as a radioligand specific for a vesicular monoamine transporter 2 (vmat2) receptor, and measuring total functional β-cell capacity (volume) of the mammal's pancreas using pet data analysis techniques.
08/14/14
20140229078
Shovel and method of controlling shovel
A shovel includes a lower-part movable body, an upper-part turnable body turnably mounted on the lower-part movable body, a boom including a first end rotatably attached onto the upper-part turnable body, an arm including a first end rotatably attached to a second end of the boom, a work element rotatably attached to a second end of the arm, an electrical energy storage device including multiple electrical energy storage cells, and mounted on the upper-part turnable body, a controller configured to control the charge and discharge of the electrical energy storage device, and multiple voltage measurement parts configured to measure the respective cell voltages of the electrical energy storage cells. Information on the cell voltages is transmitted to the controller..
08/14/14
20140228970
Tissue engineering device and construction of vascularized dermis
An inkjet printing method, system, and computer-usable tangible storage device to print cells and biomaterials for three-dimensional cellular scaffolds and engineered skin grafts are disclosed. The process simultaneously deposits living cells, nutrients, growth factors, therapeutic drugs along with biomaterial scaffolds at the right time and location.
08/14/14
20140228935
Intravascular functional element and system for such a functional element
The invention relates to an intravascular functional element with a tubular grid structure (12) that has a wire (10) or several wires (10) respectively of an alloy with nickel and titanium as alloying elements, wherein a mixed oxide layer with a layer thickness of 15 nm to 100 nm and containing tio2 and at least one nitride, especially titanium oxynitride and/or titanium nitride, is formed on the surface of the wire or on the surface of the wires (10)/of the wires (10), wherein the grid structure forms cells of mutually crossing wires (10) or wire segments of the wire (10) in longitudinal direction and in circumferential direction respectively and in circumferential direction there are disposed at least 6 cells, especially at least 12 cells, especially at least 16 cells, especially at least 24 cells, especially at least 36 cells, especially at least 48 cells.. .
08/14/14
20140228918
Actively and selectively cooled cushioning surface
A cushioning surface for cooling tissue that reaches a predefined level of immersion into the cushioning surface, comprising: a segmented fluid cushion comprising a plurality of cells interconnected to allow fluid to flow from each cell to at least one of the other plurality of cells; and wherein one or more of the plurality of cells contains a heat exchange material. The cushioning surface may further comprise a cooling element associated with and for removing heat from the one or more cells containing a heat exchange material..
08/14/14
20140228910
Method and system for processing cancer cell electrical signals for medical therapy
A scientific computer system with processor capable of recording, storing, and reprogramming the natural electrical signals of cancer cells as found in tumors of humans and animals. The reprogramming process is designed to create a confounding electrical signal for retransmission into a malignant tumor to damage or shut-down the cellular internal electrical communication system.
08/14/14
20140228857
Automated cell patch clamping method and apparatus
In an automated method for in vivo multiple cell patch clamping, cell patch clamping devices are automatically moved into position and targeted to multiple corresponding cells. Cell contact is determined by analyzing the temporal series of measured resistance levels at the clamping devices as they are moved.
08/14/14
20140228837
Control of cardiac excitability using high frequency signals
Certain embodiments of the present disclosure are directed toward devices, methods and systems for controlling depolarization in cardiac cells. One such device includes one or more circuits that are configured and arranged to generate an electrical stimulus at a high frequency.
08/14/14
20140228812
Method for reducing tumors and transforming cancer cells
This invention is related to a phenol-quinone therapy that shrinks tumors and transforms cancer cells. The therapy include four phases.
08/14/14
20140228681
In vivo optical flow imaging
Amplitude decorrelation measurement is sensitive to transverse flow and immune to phase noise in comparison to doppler and other phase-based approaches. However, the high axial resolution of oct makes it very sensitive to the pulsatile bulk motion noise in the axial direction, resulting in unacceptable signal to noise ratio (snr).
08/14/14
20140228620
Sequentially programmed magnetic field therapeutic system (spmf)
A comprehensive system for inducing cellular regeneration and/or degeneration processes and methods of treatment based on such processes through generating and applying a sequentially programmed magnetic field (spmf) to the area to be treated. In the case of regeneration and degeneration of cells, the pulsing frequencies are in the range of about 0.1 to about 2000 hz based on the indication of the disease type which was determined by either the patient's mri, ct, ultrasound or other diagnostic information.
08/14/14
20140228458
Method and apparatus for reticulating foam material using shock waves in a gaseous environment
The present document describes a method and apparatus to rapidly reticulate closed-cell or partially closed-cell foams. The method involves the propagation of an energy impulse inside the foam; the energy impulse can be a shock wave.
08/14/14
20140228441
Novel compounds modulating the hedgehog protein signaling pathway, marked forms thereof, and applications
The invention relates to compounds of formula (i), and the use thereof as a drug, particularly for the treatment of tumors associated with hyperactivation of the hedgehog protein signaling pathway, treatment of neurodegenerative diseases, treatment of diseases related to cerebral development (holoprosencephaly), for stem cell monitoring treatment of cerebrovascular accidents and cardiovascular accidents, treatment of diseases involving oligodendrocytes and diseases involving neurolemmocytes, for application thereof in vitro for modulating human or animal stem cell renewal, and for the treatment of diabetes. The invention also relates to pharmaceutical compositions having a compound of formula (i).
08/14/14
20140228436
Organ protection solution and its method of use
An organ protectant solution which is intravenously administered includes a high concentration of cell-impermeant molecules and at least one oncotic agent. The cell-impermeant molecules preferentially load into the interstitial space and the oncotic agent(s) is/are restricted to the vasculature space.
08/14/14
20140228427
Pharmaceutical composition containing wogonin as an active ingredient for preventing or treating asthma
The present invention relates to a pharmaceutical composition for the prevention or treatment of asthma comprising wogonin as an active ingredient. The wogonin of the present invention is excellent not only in relieving airway hypersensitivity that causes asthma in vivo, in inhibiting reactive oxygen species generation in the airway, and in inhibiting the infiltration of inflammatory cells in the bronchus, but also in inhibiting the generation of ige in serum and bronchoalveolar lavage fluid, and in inhibiting the expressions of th2 cytokines in the lung.
08/14/14
20140228425
Inhibitor for corneal epithelial cell death, inhibitor characterized by combining hyaluronic acid and flavin adenine dinucleotide
A combination of hyaluronic acid or a salt thereof and flavin adenine dinucleotide or a salt thereof can be an inhibitor for corneal epithelial cell death induced by ultraviolet irradiation and/or dryness because it significantly inhibits the decline of the number of living cells in corneal epithelial cells induced by ultraviolet irradiation or dryness.. .
08/14/14
20140228407
Tetra-pyridine compounds and composition for protecting cells, tissues and organs against ischemia-reperfusion injury
The invention provides a novel tetra-pyridine compound and a composition containing this compound for protecting and preserving cells, tissues and organs against ischemia-reperfusion injury. A method and use of the tetra-pyridine compound for preventing or treating ischemia-reperfusion injury or for protecting and preserving excorporeal tissue or organ from ischemia and oxygen radical-related damage are also provided..
08/14/14
20140228349
5,7-substituted-imidazo[1,2-c]pyrimidines
Compounds of formula i: and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which r1, r2, r3, r4, r5, r6, x1 and x2 have the meanings given in the specification, are inhibitors of one or more jak kinases and are useful in the treatment of autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.. .
08/14/14
20140228332
Method for enhancing the secretion of glp-1 using bitter compounds
The present invention provides a method for enhancing the secretion of glp-1 of the intestinal endocrine l-cells using a bitter compound, wherein the bitter compound is a cucurbitane-triterpenoid or allyl isothiocyanate. The bitter compound can regulate the secretion of glp-1, thus is potentially reliable for the development of medicament or healthy victual..
08/14/14
20140228246
Ecm composition, tumor microenvironment platform and methods thereof
The present disclosure relates to an extra cellular matrix composition specific for cancer type and a tumor microenvironment platform for long term culturing of tumor tissue, wherein said culturing provides human ligands and tumor tissue micro-environment to mimic physiologically relevant signalling systems. The present disclosure further relates to the development of a clinical response predictor and its application in the prognostic field (selection of treatment option for the patient) and translational biology field (development of anticancer drugs).
08/14/14
20140228236
Biomarkers, methods, and compositions for inhibiting a multi-cancer mesenchymal transition mechanism
The present invention relates to the discovery that the modulation of particular micrornas can be employed to inhibit a mesenchymal transition that, in certain instances, correlates with resistance to therapy and recurrence as the corresponding cells acquire properties of stem cells as they start undergoing this transition, as well as with invasiveness, e.g., invasion of certain cells of primary tumors into adjacent connective tissue during the initial phase of metastasis. Accordingly, the identification inhibitors of this mechanism, such as inhibitors of certain micrornas, disclosed herein, can be used for inhibiting the mesenchymal transition to reduce the invasive nature of certain cells of primary cancerous tumors and, in certain instances, to prevent the recurrence of cancer by inhibiting the induction of stem cell-like features in certain cancer cells..
08/14/14
20140228231
Method to estimate age of individual based on epigenetic markers in biological sample
The invention provides methods and materials that use observation of dna characteristics to obtain information relating to the age of individuals. The instant disclosure identifies 88 sites in or near 80 genes for which the degree of cytosine methylation in epithelial and/or white blood cells is significantly correlated with age.
08/14/14
20140228064
Code planning for wireless communications
Scrambling code conflicts can be mitigated by primary scrambling code reuse that minimizing a potential interference primary scrambling codes are applied to a first set of cells located in a portion of the network being considered. A second set of cells are evaluated for primary scrambling code reuse based on a distance parameter and/or a coverage area.
08/14/14
20140228036
Overlapping cells for wireless coverage
A system is provided for overlapping cells for wireless coverage in a cellular communication system. The system includes a beam-weight generator and beamformer coupled to the beam-weight generator.
08/14/14
20140228031
Neighbor selection for handover in a radio access network
The following methods are disclosed: a method of initiating handover of a user equipment, ue, in a cellular network comprising a plurality of enhanced node bs, enbs, the method comprising: receiving at a source enb, from the ue, a handover measurement report containing a physical cell identifier, pci, of a cell of a neighboring enb; at the source enb, performing a lookup of a neighbor relation relation table to identify a global cell identity and access mode associated with the pci; and using the identified global cell identity and the access mode to determine an enb identity for said neighboring enb. A method of initiating handover of a user equipment, ue, in a cellular net-work comprising a plurality of enhanced node bs, enbs, the method comprising: receiving at a source enb, from the ue, a handover measurement report containing a physical cell identifier, pci, of a cell of a neighboring enb; at the source enb, performing a lookup of a neighbor relation table to identify a plurality of global cell identities associated with the pci, the neighbor relation table also containing, for each such global cell identity, pcis of neighboring cells; selecting the correct global cell identity from said plurality of global cell identities by comparing the pcis of further neighboring enbs cells reported by the ue with the neighboring pcis of each of said plurality of global cell identities; and deriving from the selected correct global cell identity, an enb identity of said neighboring enb.
08/14/14
20140228028
Multiple input multiple output (mimo) based concurrent scan of neighbor cells
Methods, systems, and devices are described for concurrently performing handoff-related measurements for neighbor cells using multiple input multiple output (mimo) antenna resources. In one example, a mobile device is in communication with a serving cell.
08/14/14
20140227853
Method for forming resistance-switching memory cell with multiple electrodes using nano-particle hard mask
In a fabrication process for reversible resistance-switching memory cells, a bottom electrode layer is coated with nano-particles. The nano-particles are used to etch the bottom electrode layer, forming multiple narrow, spaced apart bottom electrode structures for each memory cell.
08/14/14
20140227840
3d non-volatile memory device and method for fabricating the same
A non-volatile memory device having a string of a plurality of memory cells that are serially coupled, wherein the string of memory cells includes a plurality of second channels of a pillar type, a first channel coupling lower end portions of the plurality of the second channels with each other, and a plurality of control gate electrodes surrounding the plurality of the second channels.. .
08/14/14
20140227823
Array of monolithically integrated thin film photovoltaic cells and associated methods
A process of forming an array of monolithic ally integrated thin film photo voltaic cells from a stack of thin film layers formed on an insulating substrate includes forming at least one cell isolation scribe in the stack of thin film layers. A second electrical contact layer isolation scribe is formed for each cell isolation scribe adjacent to a respective cell isolation scribe.
08/14/14
20140227822
Method for forming solar cells
A method for forming a thin film solar cell that includes one or more moisture barrier layer made of a water-insoluble material for protection against water and oxygen damage to the top electrode layer material is disclosed.. .
08/14/14
20140227787
Crispr-cas systems and methods for altering expression of gene products
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors and vector systems, some of which encode one or more components of a crispr complex, as well as methods for the design and use of such vectors.
08/14/14
20140227786
Retroviral vector particles and methods for their generation and use
The present invention relates to methods of host cell transduction utilising ecotropic retroviral vector particles. The retroviral vector particle may comprise an envelope of friend murine leukaemia virus, in particular the envelope encoded by molecular clone pvc-211 and the host cell may be engineered to recombinantly express the rec1 receptor.
08/14/14
20140227784
Adherent cell culture method
Provided are a method capable of evaluating adherent cells under an environment similar to an in vivo environment by a culture method similar to a two-dimensional culture, and applications thereof. An adherent cell culture method uses, as a culture chamber (10), a chamber in which two or more culture spaces each having an equivalent diameter (d) that is 1 to 5 times the diameter of a desired spheroid and each having a height (h) that is 0.3 to 5 times the equivalent diameter are arranged and a surface of each of the culture spaces has a water contact angle of 45 degrees or less.
08/14/14
20140227781
Cancer tissue-derived cell mass and a process for preparing same
Disclosed is a novel cell mass derived from a cancer tissue, which can reflect the in vivo behavior of a cancer cell correctly. Also disclosed is a process for preparing the cell mass.
08/14/14
20140227780
Method for producing megakaryocytes and/or platelets from pluripotent stem cells
Where r1 to r7, w, x, y, z, ar1 and n are as defined in the description to differentiate them into megakaryocytes and/or platelets.. .
08/14/14
20140227775
Multilayered cell culture apparatus
A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s).
08/14/14
20140227769
Device and method for industrial cultivation of cells
A compact, high-yield, bio-reactor for use as small, medium and large-scale production unit for hosting and culturing of stem cells or living cells or micro organism and producing by multiplication or expression one or more biologic compounds for medical and biological applications.. .
08/14/14
20140227768
Novel apparatus and method to propagate biological material
The present application discloses a novel microbiological apparatus and methods of using the same. The apparatus is a rolling pen comprising of a socket and a ball with its unique rolling head to transfer a biological material from a first location to a second location in an aseptic manner.
08/14/14
20140227766
Purification of biological products by constrained cohydration chromatography
Materials and methods for use of constrained cohydration agents in the purification of biological materials such as antibodies, viruses, cells, and cellular organelles in connection with convective chromatography, fluidized bed or co-precipitation applications.. .
08/14/14
20140227763
Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140227761
Polypeptides having xylanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140227760
Polypeptides having xylanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140227757
Integrated processes for conversion of lignocellulosic biomass to bioproducts and systems and apparatus related thereto
An integrated biological process for cellulosic bioproduct production is provided, which, in one embodiment, results in high ethanol productivity, enzyme recycling and reuse of yeast cells. The integrated process can be an integrated separate hydrolysis and fermentation (shf) process or an integrated fast simultaneous saccharification and co-fermentation (fsscf) process.
08/14/14
20140227756
Egvi endoglucanase and nucleic acids encoding the same
The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding egvi amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding egvi, recombinant egvi proteins and methods for producing the same..
08/14/14
20140227754
Glucoamylase variants with altered properties
The present disclosure relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present disclosure provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions and cleaning compositions.
08/14/14
20140227743
Dna polymerases with increased 3'-mismatch discrimination
Disclosed are mutant dna polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods.
08/14/14
20140227741
Biological systems for production of highest quality proteins
Vaccines and therapeutic proteins, including polyclonal and monoclonal antibodies, must be maximally pure and stable in their most active native form. This is a requirement for their maximal efficacy, specificity and stability as well as for precluding immune responses against erroneous or damaged moieties.
08/14/14
20140227739
Polypeptides having endoglucanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having endoglucanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140227738
Polypeptides having protease activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having protease activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140227736
Methods and materials for obtaining induced pluripotent stem cells
This document provides methods and materials involved obtaining induced pluripotent stem (ips) cells. For example, methods and materials for increasing the efficiency for making ips cells as well as methods and materials for selecting ips cells are provided..
08/14/14
20140227727
Unconventional protein secretion
The present invention relates to an expression cassette comprising a nucleotide sequence encoding an amino acid sequence, a fragment or variant thereof which directs unconventional protein secretion and a nucleotide sequence encoding a protein of interest. Also contemplated is a vector which comprises the expression cassette, host cells comprising the vectors as well as methods and uses for the production of a polypeptide of interest..
08/14/14
20140227705
Safe sequencing system
The identification of mutations that are present in a small fraction of dna templates is essential for progress in several areas of biomedical research. Though massively parallel sequencing instruments are in principle well-suited to this task, the error rates in such instruments are generally too high to allow confident identification of rare variants.
08/14/14
20140227703
Epigenetic marker for the identification of il17 positive t cells in complex samples
The present invention relates to a method, in particular an in vitro method for identifying il-17 expressing t cells in a blood and/or tissue sample derived from a mammal, comprising analysing the methylation status of at least one cpg position in the gene il-17a, wherein a demethylation of said at least one cpg position in said sample when compared to an analogous position in a non il-17 blood cell is indicative for a il-17 positive cd4 positive t cell. The analyses according to the invention can identify il-17 positive t cells and distinguish them from all other cells in complex samples, such as, for example, other blood cells.
08/14/14
20140227701
Methods and kits for determining dna repair capacity
In one aspect, the disclosure provides methods, compositions, vectors and kits for determining dna repair capacity in cells or a subject.. .
08/14/14
20140227694
Epigenetic markers of pluripotency
Epigenetic methods for assessing pluripotency of a cell population, such as a stem cell culture are provided. For example, pluripotency can be assessed by determining dna methylation status at the rab25, nanog, ptpn6, mgmt, gbp3 and/or lyst gene regions.
08/14/14
20140227682
System and method for the detection of abnormalities in a biological sample
The present invention is related to a method or system for the detection of abnormalities in a biological sample comprising cells. Said method or system comprises at least the following steps, or is capable to carry out, and/or comprises means capable to carry out, at least the following steps, respectively: a) acquiring an image of said sample by digital image acquisition, b) optionally, carrying out digital image processing, c) selecting a field of view, d) determining, by digital image processing, whether or not, in said field of view, cell aggregates exist, and e1) selecting a new field of view and carrying on with step c) if, in step d), it turns out that, in said field of view, the determination of cell aggregates is negative, or e2) carrying out further process steps if in step d), it turns out that, in said field of view, the determination of cell aggregates is affirmative..
08/14/14
20140227634
Gas-diffusion electrode
The invention relates to a gas-diffusion electrode provided with a sintered and cast gas-diffusion layer having a high elastic modulus. The electrode is useful as hydrogen-consuming anode or oxygen-consuming cathode of depolarised electrolytic cells such as electrowinning, chlor-alkali or electrodialysis cells..
08/14/14
20140227630
Fuel cell separator plates
The invention relates to separator plates (108) for fuel cells, and in particular to separator plates having particular geometries for improved edge sealing properties. Exemplary embodiments of the invention include a fuel cell separator plate (308) having first and second opposing faces (304, 305), the separator plate having a series of corrugations (301) extending, and providing air flow paths (302), between first and second opposing edges of the plate, wherein crests of corrugations along the first face (304) proximate the first edge (303) of the plate are depressed to be coplanar with adjacent crests of corrugations along the second face such that a greater contact surface on the second face (305) is provided compared with the first face (304)..
08/14/14
20140227629
Half-cell spacer material for enhanced flow distribution
Disclosed is method for enhancing electrolyte flowing mechanism within electrodes in flow battery cells by employing half-cell spacer screens that may be welded to at least one surface of each electrode sheet. Half-cell spacer screens may provide a constant gap thickness between electrode sheet and micro-porous separator membrane.
08/14/14
20140227627
Anion transport membrane
An anion transport membrane is provided enabling efficient anion exchange across the membrane, which could be used in applications like fuel cells, water electrolyzers, or water filtration systems. The structural membrane morphology is based on a hydrophobic polysulfone membrane backbone and co-grafted thereon hydrophilic poly(ethylene glycol) grafts and anion conducting quaternary ammonium species.
08/14/14
20140227617
System and method for managing water generated by fuel cells
A system and method for managing water produced by fuel cells where this waste water is captured and used for agricultural, industrial or community purposes along with electricity generated by the fuel cells. Water from a coastal (or lake coast) region can be converted by electricity into hydrogen and oxygen gas or hydrogen and chlorine gas with the hydrogen gas being piped to remote regions for conversion into fresh water and electricity by fuel cells.
08/14/14
20140227615
Water recapture/recycle system in electrochemical cells
A system for managing water content in one or more electrochemical cells, each comprising a plurality of electrodes and a liquid ionically conductive medium, includes a first gas-phase conduit for receiving humid gas-phase associated with the electrochemical cell. The system also includes a desiccator unit communicated to the first air conduit and configured for extracting water from the humid gas-phase.
08/14/14
20140227592
Zinc anode alkaline electrochemical cells containing bismuth
A negative electrode active material for a zinc anode alkaline electrochemical cell includes (i) particles, comprising bismuth, and (ii) powder, comprising zinc. The particles have an average particle size of at most 135 nm..
08/14/14
20140227591
Cathode
The present invention provides novel cathodes having a reduced resistivity and other improved electrical properties. Furthermore, this invention also presents methods of manufacturing novel electrochemical cells and novel cathodes.
08/14/14
20140227584
Fluorinated electrolyte compositions
Electrolyte compositions containing a solvent mixture comprising 2,2,-difluoroethyl acetate and ethylene carbonate are described. The electrolyte compositions are useful in electrochemical cells, such as lithium ion batteries..
08/14/14
20140227579
Electrode assembly having excellent degree of freedom in shape thereof in thickness direction, secondary cell battery, battery pack, and device including electrode assembly
There is provided an electrode assembly having increased degrees of structural freedom in the thickness direction thereof. The electrode assembly includes negative and positive electrodes alternately stacked with separators interposed therebetween, wherein the electrode assembly is formed by stacking n electrode stacks where n is a natural number equal to or greater than 2, each of the electrode stacks comprises electrodes having the same area and stacked with separators interposed therebetween, and neighboring electrode stacks of the electrode stacks have different electrode areas, wherein a first electrode stack of the electrode stacks is formed by stacking unit cells respectively including an odd number of electrodes, and the other electrode stacks stacked on the first electrode are formed by stacking unit cells respectively including an even number of electrodes..
08/14/14
20140227577
Middle or large-sized battery pack of novel air cooling structure
A middle- or large-sized battery pack having two or more hexahedral battery modules, each including a plurality of chargeable and dischargeable plate-shaped unit cells, mounted in a pack case, wherein the battery pack removes heat generated during the charge and discharge of the unit cells using an air cooling method, the unit cells of each of the battery modules are vertically stacked such that the number of the unit cells corresponds to a height of a battery pack installation space defined in a vehicle while neighboring unit cells are spaced apart from each other such that a coolant channel is defined between the respective unit cells, the pack case is formed in a shape corresponding to the battery pack installation space in the vehicle, and a coolant for removing heat from the unit cells is introduced through at least one side of the pack case.. .
08/14/14
20140227576
Single cell and battery made of a plurality of single cells
A single cell for a battery includes an electrode stack situated within a cell housing formed from two electrically conductive shell-shaped housing side walls situated essentially in parallel opposite one another, having a shell flange extending around the edges. The shell flanges are joined to one another to form a flange area and are electrically insulated from one another.
08/14/14
20140227574
Iron flow batterty
An iron based redox flow cell. The redox flow cell comprises a first half-cell comprising a first electrolyte providing a source of fe2+ ions and an electrode disposed within the first half-cell; a second half-cell comprising a second electrolyte providing a source of fe2+ and fe3+ ions and an electrode disposed within the second half-cell; and a separator between the first and second half-cells, where (a) the second electrolyte comprises a fe3+ stabilizing agent; (b) the first electrolyte comprises a hydrogen evolution suppressing agent; or (c) the first electrolyte comprises a hydrogen evolution suppressing agent, and the second electrolyte comprises a fe3+ stabilizing agent..
08/14/14
20140227571
Device for monitoring an electrical accumulation battery and associated method
A device is provided for monitoring an electrical accumulation battery that includes a set of cells connected in series. The device includes means for measuring a current intensity delivered by the battery; means for measuring an electrical voltage between an upstream connection point and a downstream connection point of each cell of the battery; a recorder that records a zero-current electrical voltage between the upstream connection point and the downstream connection point of each cell of the battery; and an electrical resistance estimator configured to periodically estimate an electrical resistance of each cell in the battery, between the upstream connection point and the downstream connection point..
08/14/14
20140227568
Battery system with selective thermal management
The present invention is directed to battery systems. In various embodiments, the present invention provides a battery system having a first battery group and a second battery group.
08/14/14
20140227521
Amino acid-conjugated cyanoacrylate polymer particles
Disclosed are cyanoacrylate polymer particles which comprise an amino acid(s) and have an average particle diameter of less than 1000 nm. The amino acid-containing particles according to the present invention can kill cancer cells by inducing apoptosis-like cell death.
08/14/14
20140227480
Structure for construction and method for manufacturing same
Disclosed are a structure for construction, which includes a hollow structure having a plurality of cells provided therein with hollows, arranged in a set three-dimension pattern, and partitioned by cell walls, and a cover enclosing the outside of the hollow structure, and a method of manufacturing the same. In this way, because the plurality of hollow cells of the hollow structure are partitioned by the cell walls and provided therein with the hollows, the overall weight can be reduced, and the rigidity and strength can be maintained at an adequate level despite the reduced weight.
08/14/14
20140227391
Polypeptides having alpha-glucosidase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having alpha-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides..
08/14/14
20140227341
Methods of using regenerative cells to promote wound healing
Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient.
08/14/14
20140227339
Regenerative tissue grafts and methods of making same
A graft containing a scaffold that includes a matrix in which are positioned mesenchymal progenitor cells (mpcs) has the capacity to substantially improve wound healing, including wounds resulting from injury to nerve, bone and vascular tissue. Mpcs can be harvested from debrided muscle tissue following orthopaedic trauma.
08/14/14
20140227336
Tissue engineering methods and compositions
Cells are employed in conjunction with unique biologically-compatible scaffold structures to generate differentiated tissues and structures, both in vitro and in vivo. The presently disclosed subject matter further relates to methods of forming and using improved tissue engineered scaffolds that can be used as substrates to facilitate the growth and differentiation of cells..
08/14/14
20140227321
Anti-viral compounds
Disclosed herein are compounds and related compositions for the treatment of viral infection, including rna viral infection, and compounds that can modulate the rig-i pathway in vertebrate cells, including compounds that can activate the rig-i pathway.. .
08/14/14
20140227320
Anti-viral compounds
Disclosed herein are compounds and related compositions for the treatment of viral infection, including rna viral infection, and compounds that can modulate the rig-i pathway in vertebrate cells, including compounds that can activate the rig-i pathway.. .
08/14/14
20140227308
Recombinant protein carrying human papillomavirus epitopes inserted in an adenylate cyclase protein or fragment thereof therapeutic uses thereof
The invention relates to a recombinant protein comprising one or several polypeptides bearing one or several epitopes of one or several hpv antigens, said polypeptides being inserted in the same or different permissive sites of an adenylate cyclase (cyaa) protein or of a fragment thereof, wherein said cyaa fragment retains the property of said adenylate cyclase protein to target antigen presenting cells. It also concerns polynucleotides encoding the same.
08/14/14
20140227305
Epstein-barr-virus vaccine
The present invention relates to a vaccine comprising a particle, said particle comprising (i) at least one epstein-barr virus (ebv) structural polypeptide, (ii) at least one ebv lytic polypeptide, (iii) membrane lipids, said particle being devoid of ebv dna, wherein (a) the b-cell transformation capacity of one or more ebv polypeptides required for b-cell transformation as comprised in said particle is disabled while their immunogenicity is maintained; and/or (b) said particle is devoid of one or more ebv polypeptides required for b-cell transformation. Furthermore, the invention relates to a method for generating a particle, to a cell obtained in the method of the invention, a kit comprising the vaccine or the particle generated according to the method of the invention.
08/14/14
20140227304
Vaccines for preventing and treating alzheimer's disease
Disclosed herein are vaccines comprising an amyloid beta antigen and a nucleic acid encoding the amyloid beta antigen, or a variant thereof. T cell proliferation can be inhibited and itreg cells can be stimulated in the subject administered the vaccine.
08/14/14
20140227296
Modified glycolipids and methods of making and using the same
The invention is directed to compositions and methods related to proteins that are physically associated with ceramide-like glycolipids for use as activators of nkt cells. The compositions and methods of the present invention are useful for the prevention and treatment of diseases..
08/14/14
20140227292
Anti-mcam antibodies and associated methods of use
Described herein are anti-mcam antibodies and antigen binding fragments thereof that are capable of inhibiting the interaction between mcam and its ligand, a protein comprising a laminin α-4 chain. These anti-mcam antibodies and antigen binding fragments thereof may be useful for, for example, treating inflammatory conditions characterized by the infiltration of mcam-expressing cells into a site of inflammation in the body..
08/14/14
20140227290
Method for increasing n-glycosylation site occupancy on therapeutic glycoproteins produced in pichia pastoris
Described is a method for increasing the n-glycosylation site occupancy of a therapeutic glycoprotein produced in recombinant host cells modified as described herein and genetically engineered to express the glycoprotein compared to the n-glycosylation site occupancy of the therapeutic glycoprotein produced in a recombinant host cell not modified as described herein. In particular, the method provides recombinant host cells that overexpress a heterologous single-subunit oligosaccharyltransferase, which in particular embodiments is capable of functionally suppressing the lethal phenotype of a mutation of at least one essential protein of the yeast oligosaccharyltransferase (otase) complex, for example, the leishmania major stt3d protein, in the presence of expression of the host cell genes encoding the endogenous otase complex.
08/14/14
20140227288
Pnmt as a novel marker for progenitor cells
In certain aspects, the present invention provides methods and compositions relating to a pnmt-positive progenitor cell. In certain aspects, the present invention relates to methods for isolating and transplanting the subject progenitor cells, and methods for treating diseases such as myocardiac injuries and neurodegenerative disorders..
08/14/14
20140227286
Annexin a2 as immunological target
Annexina2 (anxa2), a member of the annexin family of calcium-dependent, phospholipid binding proteins, is one of a panel of identified antigens recognized by the post-vaccination sera of patients who demonstrated prolonged disease-free survival following multiple vaccinations. Annexina2 is abundantly expressed in pancreatic adenocarcinomas and cell surface/membrane annexina2 increases with the progression from premalignant lesions to invasive pancreatic adenocarcinomas.
08/14/14
20140227278
Antibodies to human signal peptide-containing proteins
The invention provides a human signal peptide-containing proteins (sigp) and polynucleotides which identify and encode sigp. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists.
08/14/14
20140227275
Methods of treating and diagnosing pancreatitis
The present invention provides nucleotide and amino acid sequences that identify and encode novel expressed chemokines (panec-1 and panec-2) from human pancreas cells. The present invention also provides for antisense molecules to the nucleotide sequences which encode panec-1 and panec-2, expression vectors for the production of purified panec-1 and panec-2, antibodies capable of binding specifically to panec-1 and panec-2, hybridization probes or oligonucleotides for the detection of panec-1- or panec-2-encoding nucleotide sequences, genetically engineered host cells for the expression of panec-1 and panec-2, diagnostic tests for chemokine activation based on panec-1- and panec-2-encoding nucleic acid molecules and antibodies capable of binding specifically to the protein..
08/14/14
20140227273
Multi-specific binding molecules targeting aberrant cells
Described are proteinaceous molecules comprising at least two, preferably three to six, binding domains that bind specifically to at least two different binding sites on aberrant cells. These multi-domain and multi-specific binding molecules are preferably used in selectively modulating biological processes.
08/14/14
20140227272
Anti-leukocyte adhesion for the mitigation of potential adverse events caused by cd3-specific binding domains
The present invention relates in essence to a compound which decreases or inhibits the binding of mammalian t-cells to mammalian endothelial cells for use in a method of prophylaxis and/or amelioration and/or treatment of clinical adverse events caused by therapy which comprises re-directing of t-cells against target cells in a patient. Methods of treatment of patients having or being at risk of clinical adverse events caused by therapy which comprises re-directing of t-cells against target cells are also contemplated..
08/14/14
20140227270
Bispecific anti-cxcr7 immunoglobulin single variable domains
The present invention relates to particular polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the present invention provides immunoglobulin single variable domains inhibiting cxcr7 mediated tumour growth..
08/14/14
20140227268
Agents that engage antigen-presenting cells through dendritic cell asialoglycoprotein receptor (dc-asgpr)
The present invention includes compositions and methods for making and using anti dc-asgpr antibodies that can, e.g., activate dcs and other cells.. .
08/14/14
20140227263
Use of fgfr1 extra cellular domain proteins to treat cancers characterized by ligand-dependent activating mutations in fgfr2
The present invention relates to the use of fibroblast growth factor receptor i (fgfr1) extracellular domain (ecd) polypeptides for treatment of cancers characterized by ligand dependent activating mutations in fibroblast growth factor receptor 2 (fgfr2). For example, the present invention relates to the treatment of endometrial cancers and other cancers wherein tumor cells express fgfr2 mutants in the igii-igiii hinge region or igiii domain of the protein, such as at amino acid positions 252 and/or 253..
08/14/14
20140227262
Pd-1 antagonists and methods for treating infectious disease
Methods and compositions for treating an infection or disease that results from (1) failure to elicit rapid t cell mediated responses, (2) induction of t cell exhaustion, t cell anergy or both, or (3) failure to activate monocytes, macrophages, dendritic cells and/or other apcs, for example, as required to kill intracellular pathogens. The method and compositions solve the problem of undesired t cell inhibition by binding to and blocking pd-1 to prevent or reduce inhibitory signal transduction, or by binding to ligands of pd-1 such as pd-l1, thereby preventing (in whole or in part) the ligand from binding to pd-1 to deliver an inhibitory signal.
08/14/14
20140227261
Use of omega fatty acids for treating disease
Eicosapentaenoic acid (epa) and docosahexaenoic acid (dha), or a salt or an ester thereof, are provided for use in the treatment and/or prophylaxis of a condition selected from macular oedema, conditions causing damage to retinal photoreceptors and/or retinal pigment epithelial cells, and dry eyes in a mammal, wherein the combined dosage of eicosapentaenoic acid and docosahexaenoic acid is from 5 mmol to 25 mmol per day, and wherein the molar ratio of eicosapentaenoic acid to docosahexaenoic acid is in the range of from 1:1 to 5:1. Compositions comprising epa and dha and at least one pharmaceutically acceptable excipient, and kits containing epa, dha and further therapeutic agents are also provided.
08/14/14
20140227257
Monoclonal antibodies that neutralize anthrax protective antigen (pa) toxin
The present invention relates to monoclonal antibodies that bind or neutralize anthrax protective antigen (pa) toxin. The invention provides such antibodies, fragments of such antibodies retaining anthrax pa toxin-binding ability, fully human or humanized antibodies retaining anthrax pa toxin-binding ability, and pharmaceutical compositions including such antibodies.
08/14/14
20140227253
Antigen binding molecules that bind egfr, vectors encoding same, and uses thereof
The present invention relates to antigen binding molecules (abms). In particular embodiments, the present invention relates to recombinant monoclonal antibodies, including chimeric, primatized or humanized antibodies specific for human egfr.
08/14/14
20140227246
Pharmaceutical anti-angiogenic composition including a microrna-382 inhibitor
The present invention relates to an anti-angiogenic composition, and more particularly, to a pharmaceutical anti-angiogenic composition including a microrna-382 inhibitor. The inventors of the present invention have confirmed that microrna-382, the expression of which is elevated in stomach cancer cells in a low oxygen environment, affects the promotion of angiogenesis induced in a low oxygen environment.
08/14/14
20140227245
Pharmaceutical angiogenic composition including a microrna-382 activator
The present invention relates to an angiogenic composition, and more particularly, to a pharmaceutical angiogenic composition including a microrna-382 activator. The inventors of the present invention have confirmed that microrna-382, the expression of which is elevated in stomach cancer cells in a low oxygen environment, affects the promotion of angiogenesis.
08/14/14
20140227240
Regeneration of spinal discs
Compositions and processes for the effective and efficient regeneration of spinal discs are provided. These compositions contain stem cells, donor cells, and platelet plasma compositions.
08/14/14
20140227237
Rna engineered t cells for the treatment of cancer
The present invention relates to compositions and methods for generating rna chimeric antigen receptor (car) transfected t cells. The rna-engineered t cells can be used in adoptive therapy to treat cancer..
08/14/14
20140227236
Hiv-resistant stem cells and uses thereof
Disclosed are recombinant stem cells that are resistant to hiv infection. Also disclosed are their uses in treating aids..
08/14/14
20140227235
Cartilage cell treatment comprising collagen, hyaluronic acid derivative, and stem cell derived from mammal umbilical cord
The present invention relates to a medical composite biomaterial. More specifically, the present invention relates to a medical composite biomaterial including collagen and a hyaluronic acid derivative.
08/14/14
20140227234
Methods of using regenerative cells to promote wound healing
Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient.
08/14/14
20140227233
Treatment of urinary incontinence with regenerative glue
The invention relates to methods for the treatment of urinary incontinence (ui) and stress urinary incontinence (sui) in both men and women by replacement of a damaged, absent or injured pubo-urethral ligament (pul) via a simple injection of “regenerative glue.” for example, in the case of ui, the injection of “regenerative glue” at the pul site will adhere the ventral surface of the urethra to the dorsal surface of the symphysis pubis (i.e. The space of retzius), and further provide regenerative material for continuous replacement of deficient tissues and cells.
08/14/14
20140227232
Methods and compositions for delivery of exogenous factors to nervous system sites
The present invention relates to treatment methods and methods for sustained delivery of one or more exogenous factors to desired nervous system sites. In certain embodiments, the invention relates to the use of biodegradable microspheres to deliver exogenous factors, such as the morphogenic factor, sonic hedgehog (shh), to the site of spinal cord injury.
08/14/14
20140227226
Infectivity-enhanced conditionally-replicative adenovirus and uses thereof
A modified adenovirus capable of overcoming the problem of low level of coxsackie-adenovirus receptor (car) expression on tumor cells and methods of using such adenovirus are provided. The fiber protein of the adenovirus is modified by insertion or replacement so as to target the adenovirus to tumor cells, and the replication of the modified adenovirus is limited to tumor cells due to specific promoter control or mutations in e1a or e1b genes..
08/14/14
20140227222
Cyclin dependent kinase inhibitors and methods of use
The presently disclosed subject matter relates to methods and compositions for protecting healthy cells from damage due to dna damaging agents. In particular, the presently disclosed subject matter relates to the protective action of selective cyclin dependent kinase 4/6 (cdk4/6) inhibitors administered to subjects that have been exposed to or that are at risk of exposure to dna damage..
08/14/14
20140227185
Glutathione-based drug delivery system
The invention relates to methods of targeted drug delivery of compounds, including, chemical agents, (poly)peptides and nucleic acid based drugs (like dna vaccines, antisense oligonucleotides, ribozymes, catalytic dna (dnazymes) or rna molecules, sirnas or plasmids encoding thereof). Furthermore, the invention relates to targeted drug delivery of compounds to extravascular and intracellular target sites within cells, tissues and organs, in particular to target sites within the central nervous system (cns), into and across the blood-brain barrier, by targeting to glutathione transporters present on these cells, tissues and organs.
08/14/14
20140227178
Humanized anti-hla-dr antibodies
The present invention concerns compositions and methods of use of humanized anti-hla-dr antibodies. In preferred embodiments, the antibodies induce apoptosis and inhibit proliferation of lymphoma cells without inducing cdc or adcc.
08/14/14
20140227175
Cathepsin-binding compounds bound to a carrier and their diagnostic use
The invention relates to cathepsin-binding compounds bound to a carrier comprising a diagnostic moiety, for use in the diagnosis of inflammatory diseases, and/or for use in the diagnosis of neoplastic diseases, wherein the cathepsin-binding compound binds to inflammatory cells of the tumour stroma. The invention also relates to cathepsin b-targeting compounds and cathepsin b-binding and liposome-binding compounds..
08/14/14
20140227174
Skin permeating and cell entering (space) peptides and methods of use therefor
Compositions that facilitate the delivery of an active agent or an active agent carrier wherein the compositions are capable of penetrating the stratum corneum (sc) and/or the cellular membranes of viable cells are provided. In some embodiments, the compositions include a peptide, an active agent, and a carrier that includes the active agent, wherein the peptide has an amino acid sequence set forth in any of seq id nos: 1-18; the peptide is associated with and/or conjugated to the active agent, the carrier, or both; the carrier is selected from the group consisting of a micelle, a liposome, an ethosome, and combinations thereof; and the composition is capable of penetrating a stratum corneum (sc) layer when contacted therewith or penetrating a cell when contacted therewith, and optionally wherein the composition further includes one or more free peptides having an amino acid sequence set forth in any of seq id nos: 1-18.
08/14/14
20140227172
Diagnosis and treatment of prostate cancer
The methods of the present disclosure are directed toward methods of diagnosis and treatment of cancer in a subject. The present disclosure provides methods of diagnosing abnormal cells in a subject by measuring the level of hexim-1 in a sample from the subject, where elevated levels of hexim-1 indicate abnormal cells.
08/14/14
20140227135
Cell series structure for analysis device
To reduce the amount of warping deformation of a reaction cell block for an analysis device in which reaction cells and a holder are formed integrally in a complex shape with a resin material. At least one rib is provided on the front surface or the rear surface of one or both of a reaction cell arrangement face 4 or a coupling face 5 of a reaction cell block 18, the coupling face 5 being adapted to join the reaction cell arrangement face 4 and a flange face for attachment to an analysis device, whereby rigidity is increased..


Popular terms: [SEARCH]



Follow us on Twitter
twitter icon@FreshPatents

###

This listing is a sample listing of patent applications related to Cells for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Cells with additional patents listed. Browse our RSS directory or Search for other possible listings.
     SHARE
  
         


FreshNews promo



0.9174

6555

1 - 1 - 155