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Cells patents



      
           
This page is updated frequently with new Cells-related patent applications. Subscribe to the Cells RSS feed to automatically get the update: related Cells RSS feeds. RSS updates for this page: Cells RSS RSS


Battery pack

Electrocatalyst for solid polymer fuel cell

Date/App# patent app List of recent Cells-related patents
07/17/14
20140201871
 Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same patent thumbnailnew patent Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
07/17/14
20140201862
 Compositions and methods for altering alpha- and beta-tocotrienol content patent thumbnailnew patent Compositions and methods for altering alpha- and beta-tocotrienol content
Preparation and use of isolated nucleic acids useful in altering the oil phenotype in plants. Isolated nucleic acids and their encoded polypeptides that alter alpha- and beta-tocotrienol content in seeds and oil obtained from the seeds.
07/17/14
20140201858
 Methods for site-specific genetic modification in stem cells using xanthomonas tal nucleases (xtn) for the creation of model organisms patent thumbnailnew patent Methods for site-specific genetic modification in stem cells using xanthomonas tal nucleases (xtn) for the creation of model organisms
The invention relates to organisms and compositions comprising one or more stem cells or one or more embryos, wherein the one or more stem cells or one or more embryos comprise one or more of the following mutations: (i) a deletion mutation; (ii) a knockout mutation; and/or (iii) an addition of a heterologous nucleic acid sequence; wherein the one or more mutations of (i), (ii), and/or (iii) are site-specific mutations caused by a xanthomonas tal nuclease (xtn). The invention also relates to method of mutating an embryo, ips cell, stem cell, or more particularly a spermatogonial stem cell by exposing the nucleic acid sequence contained within such embryos or cell with a xanthomonas tal nuclease..
07/17/14
20140201856
 Animal models and therapeutic molecules patent thumbnailnew patent Animal models and therapeutic molecules
The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.. .
07/17/14
20140201855
 Mutant luciferases patent thumbnailnew patent Mutant luciferases
Described are mutant luciferases, nucleic acids that encode them, cells and animals expressing them, methods of use thereof, and kits.. .
07/17/14
20140201854
 Animal models and therapeutic molecules patent thumbnailnew patent Animal models and therapeutic molecules
The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.. .
07/17/14
20140201695
 Power grid design for integrated circuits patent thumbnailnew patent Power grid design for integrated circuits
A method of generating a power grid to supply current to a plurality of cells of an integrated circuit includes routing an initial power grid representing a power usage estimate for the plurality of cells. The method also includes performing power grid analysis prior to routing of signal wires to make a determination of whether the initial power grid meets power requirements of the integrated circuit, and selectively modifying portions of the initial power grid based on the performing the power grid analysis to generate the power grid..
07/17/14
20140201606
 Error protection for a data bus patent thumbnailnew patent Error protection for a data bus
A system for providing error detection or correction on a data bus includes one or more caches coupled to a central processing unit and to a hub by one or more buses. The system also includes a plurality of arrays, each array disposed on one of the buses.
07/17/14
20140201600
 Apparatus and method for encoding data for storage in multi-level nonvolatile memory patent thumbnailnew patent Apparatus and method for encoding data for storage in multi-level nonvolatile memory
A controller for a nonvolatile memory includes an encoder and a decoder. The memory includes memory cells that each store data using more than two levels.
07/17/14
20140201599
 Error protection for integrated circuits in an insensitive direction patent thumbnailnew patent Error protection for integrated circuits in an insensitive direction
A method for providing error detection, or error detection combined with error correction, to an array of storage cells includes determining a sensitive direction and an insensitive direction of the storage cells and adding an error control mechanism to the array of storage cells in the insensitive direction. The insensitive direction is a direction perpendicular to a width of a gate conductor of the storage cells..
07/17/14
20140201596
new patent Adaptation of analog memory cell read thresholds using partial ecc syndromes
A method includes storing data that is encoded with an error correction code (ecc) in a group of analog memory cells. The memory cells in the group are read using multiple sets of read thresholds.
07/17/14
20140201593
new patent Efficient memory architecture for low density parity check decoding
A low density parity check (ldpc) decoder integrated on a single semiconductor substrate may comprise one or more arrays of first-type memory cells and one or more arrays of second-type memory cells. The ldpc decoder may be configured to store intrinsic messages in the array of first-type cells and to store extrinsic messages in the array of second-type cells.
07/17/14
20140201584
new patent Scan test circuitry comprising at least one scan chain and associated reset multiplexing circuitry
An integrated circuit comprises scan test circuitry and additional circuitry subject to testing utilizing the scan test circuitry. The scan test circuitry comprises at least one scan chain having a plurality of scan cells.
07/17/14
20140201547
new patent Selective precharge for power savings
Embodiments of a memory device are disclosed that may allow for detecting the opportunity for energy savings and implementing the energy savings for each access to the memory device. The memory device may include a plurality of columns, an address comparator, and a timing and control circuit.
07/17/14
20140201495
new patent Page miss handler including wear leveling logic
Embodiments of the invention describe an apparatus, system and method for utilizing a page miss handler having wear leveling logic/modules for memory devices. Embodiments of the invention may track an amount of writes directed towards cells of a memory device, and determine whether a linear address specified by a system write transaction is included in a translation-lookaside buffer (tlb).
07/17/14
20140201484
new patent Data access and management system as well as a method for data access and data management for a computer system
The present invention permits improved data access and improved data management in a computer system. To this end, data are divided into individual partial data (f) and stored in cells (z) of storage devices (c) in such a way that the partial data (f) being accessed and managed are present in the computer system in a redundant manner.
07/17/14
20140201433
new patent Selective activation of programming schemes in analog memory cell arrays
A method for data storage includes defining a first programming scheme that programs a group of analog memory cells while reducing interference caused by at least one memory cell that neighbors the group, and a second programming scheme that programs the group of the analog memory cells and does not reduce all of the interference reduced by the first programming scheme. One of the first and second programming schemes is selected based on a criterion defined with respect to the analog memory cells.
07/17/14
20140201339
new patent Method of conditioning communication network data relating to a distribution of network entities across a space
A method and apparatus for conditioning communication network data relating to a distribution of network entities across a space, for subsequent processing of the network data, is disclosed. The method comprises dividing the space into a grid comprising a plurality of discrete cells, so that each cell comprises a unique location within the space.
07/17/14
20140201219
new patent Method and apparatus for searching an image, and computer-readable recording medium for executing the method
The present disclosure relates to a method and apparatus for searching an image, and to a computer-readable recording medium for executing the method. The apparatus for searching an image of the present disclosure obtains features of an input image; and obtains words that correspond to the features respectively and an adjacent word that is adjacent to the words corresponding to the features.
07/17/14
20140201128
new patent System and method for processing and/or analyzing olap based data according to one or more parameters
A system and method for processing a base vector derived from data stored in an olap cube. The system comprises a component configured for defining a base vector and a comparison vector, wherein the comparison vector comprises one or more dimensions corresponding to dimensions of the base vector.
07/17/14
20140200723
new patent System and method for energy distribution
A dispatch planner (dp) is a component in an energy system controller that controls the operation of energy resources interconnected into one energy system to provide optimal energy management for a customer. In one embodiment, the energy storage system includes an electric load, dispatchable sources of energy such as an electrical grid, diesel generators, combined heat and power generators; renewable sources of energy such as photo-voltaic cells and wind turbines; and stored energy resources such as electrochemical batteries or pumped hydro reserves..
07/17/14
20140200678
new patent Biomaterials with microsphere gradients and core and shell microspheres
Methods can prepare tissue engineering scaffolds that include a plurality of biocompatible core/shell microspheres linked together to form a three-dimensional matrix. The matrix can include a plurality of pores for growing cells.
07/17/14
20140200660
new patent Valve prosthesis frames
A prosthesis can include a collapsible, reexpandable frame comprising first, second, and third sets of struts that define first and second rows of expandable cells. In some embodiments, the struts of the first, second, and third set of struts can be tapered.
07/17/14
20140200503
new patent Systems, devices, and methods for isolation of stem cells
The present disclosure relates, in some embodiments, to apparatus, systems, methods, and compositions for purifying cells (e.g., adipocytes, stem cells) from mammalian tissues (e.g., adipose tissues). For example, the present disclosure relates to apparatus, systems, methods, and compositions for purifying and/or preserving adipocytes and/or stem cells from fat tissue of a mammalian subject according to some embodiments..
07/17/14
20140200481
new patent Apparatus and methods for noninvasive monitoring of cancerous cells
A system for noninvasively monitoring cancerous cells within bodily fluid accumulated due to ascites, pleural effusion or pericardial effusion is provided including an implantable pump having control circuitry; a charging and communication system configured to periodically charge and communicate with the implantable pump to retrieve performance data; and monitoring and control software, suitable for use with conventional personal computers, for configuring and controlling operation of the implantable pump and charging and communication system. The implantable pump is configured to move fluid containing cancerous cells from a body cavity to the bladder such that the fluid may be excreted during urination, collected and analyzed with an analysis station to assess progress of the cancer or efficacy of a cancer treatment program..
07/17/14
20140200458
new patent Three dimensional metamaterials from conformal polymer coating layers
A manufacture for supporting propagation of terahertz waves includes a stack of layers made of a conformal protective polymer coating material; and an array of cells patterned on each of said layers, each cell including a metallic structure.. .
07/17/14
20140200330
new patent Isolation of phosphoproteins, glycoproteins and fragments thereof
The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. A lanthanide metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups.
07/17/14
20140200260
new patent Methods for determining and inhibiting rheumatoid arthritis associated with the braf oncogene in a subject
The invention provides methods for determining whether a subject is suffering from a rheumatoid arthritis associated with the braf oncogene comprising contacting isolated fibroblasts from the subject with a molecule or pool of molecules directed to the braf oncogene; and culturing the sample in the presence of the agent and determining whether braf oncogene expression by the cell is decreased and/or whether cells in the sample return to a less transformed phenotype, exhibit decreased cell proliferation and/or exhibit increased contact inhibition, any of which is indicative that the subject is suffering from a rheumatoid arthritis associated with the braf oncogene.. .
07/17/14
20140200250
new patent Anti-cancer agents
Described herein are compounds that may be selectively activated to produce active anti-cancer agents in tumor cells. Also disclosed are pharmaceutical compositions comprising the compounds, and methods of treating cancer using the compounds..
07/17/14
20140200145
new patent Method of metabolic evolution
The invention relates to a method for metabolic evolution of a variant of a natural small aromatic molecule product of a metabolic pathway, by somatic in vivo assembly and recombination of said metabolic pathway employing a gene mosaic of at least one gene a, which comprises a) in a single step procedure (i) transforming a cell with at least one gene a having a sequence homology of less than 99.5% to another gene to be recombined that is an integral part of the cell genome or presented in the framework of a genetic construct, (ii) recombining said genes, (iii) generating a gene mosaic of the genes at an integration site of a target genome, wherein said at least one gene a has a single flanking target sequence either at the 5′ end or 3′ end anchoring to the 5′ or 3′ end of said integration site, (iv) recombining eventual further genes of said metabolic pathway, and b) selecting clones comprising said gene mosaic and said eventual further genes capable of expressing said variant, methods of preparing a library of cells producing variants of natural small aromatic molecule products of a metabolic pathway, the libraries so produced and used to prepare said variants.. .
07/17/14
20140200029
new patent Measurement configuration map for measurement event reporting in cellular communications network
Cells of a cellular communications network are divided into a plurality of areas. For each area, measurement event data is determined, wherein the measurement event data trigger a measurement event in a user equipment, and when the measurement event is detected by the user equipment based on the measurement event data, the measurement event is reported by the user equipment.
07/17/14
20140200020
new patent Channel quality index determination
A method of a transceiver arranged to operate in a cellular communication system comprising cells is disclosed. The method comprises receiving a transmission from a first cell; determining an interfering signal and its occupation in time and/or frequency; determining reduced values in the received signal corresponding to the occupation in time and/or frequency of the interfering signal; and measuring a quotient between desired signal and non-desired signal of reference symbols of the received signal.
07/17/14
20140199821
new patent Variable-resistance material memories and methods
Variable-resistance memory material cells are contacted by vertical bottom spacer electrodes. Variable-resistance material memory spacer cells are contacted along the edge by electrodes.
07/17/14
20140199806
new patent Dielectric structures in solar cells
A dielectric, structure and a method of forming a dielectric structure for a rear surface of a silicon solar cell are provided. The method comprises forming a first dielectric layer over the rear surface of the silicon solar cell, and then depositing a layer of metal such as aluminum over the first dielectric layer.
07/17/14
20140199805
new patent Tio2 aerogel-based photovoltaic electrodes and solar cells
A photoelectrode is disclosed having a conductive lead and a titania aerogel in electrical contact with the lead. The aerogel is coated with a photosensitive dye.
07/17/14
20140199782
new patent Method to screen high affinity antibody
The current invention reports a method for producing an antibody comprising the steps of a) providing a plurality of hybridoma cells each expressing an antibody, b) determining the time dependent amount of said antibody bound to the respective antigen by surface plasmon resonance at different temperatures and different antibody concentrations, c) calculating with the time dependent amount determined in b) based on equations (ii) to (xiii) at least the thermodynamic parameters (i) standard association binding entropy (Δs°‡ass), (ii) standard dissociation binding entropy (Δs°‡diss), (iii) standard binding entropy (Δs°), (iv) free standard binding enthalpy (Δg°), (v) standard dissociation free binding enthalpy (Δg°‡diss), (vi) standard association free binding enthalpy (Δg°‡ass), (vii) −tΔs°, (viii) dissociation rate constant kd, (ix) equilibrium binding constant kd, and (x) association rate constant ka, d) selecting a hybridoma cell producing an antibody with at least two of the following: i) a standard association binding entropy of less than 10 j/k*mol, ii) an absolute standard dissociation binding entropy of 100 j/mol*k or more, iii) an absolute standard binding entropy of 100 j/mol*k or more, e) producing an antibody by cultivating said selected cell under conditions suitable for the expression of said antibody and recovering said antibody from the cells or/and the cultivation medium.. .
07/17/14
20140199766
new patent Transgenic system for reversibly immortalizing mammalian quiescent cells
A transgene for endowing human quiescent cells from primary cultures with exogenously inducible telomere length homeostasis and cell cycle traverse is described. The transgene includes at least three promoter sequences; a g1-specific rna interference sequence which is operably linked downstream of a first promoter sequence; a telomere length maintenance gene sequence which is operably linked downstream to a second promoter sequence; a scaffold/matrix attachment region (s/mar) element positioned downstream in frame with said telomere length maintenance gene sequence and an exogenously-inducible transcriptional regulation system.
07/17/14
20140199763
new patent Compositions and methods to immunize against hepatitis c virus
Compositions comprising viral antigens and antigenic peptides corresponding to or derived from hepatitis c virus (hcv) proteins or fragments thereof, fused to heavy and/or light chain of antibodies, or fragments thereof specific for dendritic cells (dcs) are described herein. Included herein are immunostimulatory compositions (hcv vaccines, hcv antigen presenting dendritic cells, etc.) and methods for increasing effectiveness of hcv antigen presentation by an antigen presenting cell, for a treatment, a prophylaxis or a combination thereof against hepatitis c in a human subject, and methods of providing immunostimulation by activation of one or more dendritic cells, methods to treat or prevent hepatitis c..
07/17/14
20140199761
new patent Promoter-regulated differentiation-dependent self-deleting cassette
Targeting constructs and methods of using them are provided for differentiation-dependent modification of nucleic acid sequences in cells and in non-human animals. Targeting constructs comprising a promoter operably linked to a recombinase are provided, wherein the promoter drives transcription of the recombinase in an differentiated cell but not an undifferentiated cell.
07/17/14
20140199753
new patent Sporulation-deficient b. texasporus cells and methods for efficient and cost-effective inactivation and use thereof
Novel strains and methods for their use are provided. Particularly, foods and other oral products or treatments containing sporulation-deficient brevibacillus strain when administered to a subject can inhibit or reduce the number of pathogens in the subject and improve the health of the subject..
07/17/14
20140199751
new patent Protein extraction
A method for releasing the content of the periplasmic space of bacterial cells is provided, which comprises incubating the bacterial cells in a solution containing styrene maleic acid copolymer (sma). Also provided is a method of preparing a substantially pure sample of recombinant polypeptide.
07/17/14
20140199748
new patent Kit and method for the capture of tumor cells
The invention relates to a kit and method for the capture of tumor cells in a body fluid sample. The kit and method of the invention can capture living tumor cells but not non-living tumor cells or cell fragments so that the tumor species can be further identified by further culture of the captured tumor cells.
07/17/14
20140199743
new patent High-nitrogen loading for ammonia processing via anaerobic digestion
A method and system to improve anaerobic digestion are disclosed. Simultaneous digestion of dairy manures with various food wastes improves anaerobic process stability and methane production.
07/17/14
20140199742
new patent Method for producing isopropyl alcohol by continuous culture
A method of producing isopropyl alcohol includes: culturing an isopropyl alcohol-producing escherichia coli under a bacterial cell growth condition in which the escherichia coli stably proliferates in an isopropyl alcohol production period while continuously supplying a substrate solution to a culture tank and continuously removing a product-containing culture solution from the culture tank, the substrate solution containing a plant-derived raw material, the number of cells of the isopropyl alcohol-producing escherichia coli in the culture tank being maintained during the culturing, and the isopropyl alcohol-producing escherichia coli having isopropyl alcohol production ability introduced or modified by genetic recombination; bringing the isopropyl-alcohol-producing escherichia coli into contact with the plant-derived raw material in the culture tank to produce isopropyl alcohol; and recovering the isopropyl alcohol produced by the isopropyl alcohol-producing escherichia coli from the culture solution that contains the product and that has been removed from the culture tank.. .
07/17/14
20140199736
new patent Pichia ciferrii cells and use thereof
The invention relates to genetically modified pichia ciferrii cells, to the use thereof and to a method of producing sphingoid bases and sphingolipids.. .
07/17/14
20140199729
new patent Method for reducing heterogeneity of antibodies and a process of producing the antibodies thereof
The present disclosure relates to a method of reducing heterogeneity in antibodies during culturing, wherein the heterogeneity is due to proportion of charge variant of the antibody. The disclosure also comprises a process of growing cells in a cell culture system that results in antibodies with the reduced heterogeneity.
07/17/14
20140199726
new patent Production of biofuel from tissue culture sources
The present invention provides a method for the production of at least one fatty acid and/or oil from a plant cell suspension culture, the method comprising (i) maintaining a cell suspension culture of oil-producing plant cells under conditions such that the cultured cells synthesise and secrete at least one fatty acid and/or oil into the cell suspension culture medium; and (ii) extracting the thus secreted at least one fatty acid and/or oil from the cell suspension culture medium.. .
07/17/14
20140199719
new patent Impedance-based sensing of adherent cells on a digital microfluidic device
Devices and methods are provided for measuring, on a digital microfluidic platform, electrical signals associated with the impedance of adherent cells. In one embodiment, a sub-droplet of cell culture media containing adherent cells is passively dispensed at a pre-selected electrode location where a local hydrophilic surface region is provided, and adherent cells are attached to the local hydrophilic surface region.
07/17/14
20140199717
new patent Multiplex mrm assay for evaluation of cancer
The current disclosure provides specific peptides, and derived ionization characteristics of the peptides from the estrogen receptor (er), progesterone receptor (pr), and/or antigen ki67 (ki67) proteins that are particularly advantageous for quantifying the er, pr, and/or ki67 proteins directly in biological samples that have been fixed in formalin by the method of selected reaction monitoring/multiple reaction monitoring (srm/mrm) mass spectrometry. Such biological samples are chemically preserved and fixed wherein the biological sample is selected from tissues and cells treated with formaldehyde containing agents/fixatives including formalin-fixed tissue/cells, formalin-fixed/paraffin embedded (ffpe) tissue/cells, ffpe tissue blocks and cells from those blocks, and tissue culture cells that have been formalin fixed and or paraffin embedded.
07/17/14
20140199714
new patent Method for detecting cancer cells metastasizing into sentinel lymph node
A method for detecting a sentinel lymph node generating a microenvironment suitable for micrometastasis within the sentinel lymph node of carcinoma cells from a primary tumor or for detecting micrometastasis within the sentinel lymph node. A detecting agent is injected into the primary tumor, or tissue or a lymph node nearby the tumor, which allows the detecting agent to reach the sentinel lymph node by lymphatic circulation.
07/17/14
20140199708
new patent Cell-based methods for measuring activity of a protein inhibitor
The invention provides a method for determining the activity of an inhibitor of a target protein that has a deleterious effect on cell growth. The principle of the claimed method is that a compound that inhibits the function of an overexpressed protein will relieve the detrimental effect of such overexpression in a concentration-dependent manner, thereby allowing the determination of the activity of the compound in inhibiting its target protein in live cells..
07/17/14
20140199706
new patent Methods and compositions for enhancing proteasome activity
This invention relates to methods and compositions for enhancing proteasome activity in a cell. The methods and compositions for enhancing the activity of the proteasome in cells modulate the activity of ubp6 (yeast) or usp14 (human), an endogenous inhibitor of the proteasome.
07/17/14
20140199702
new patent Canceration information providing method and canceration information providing device
There is provided a canceration information providing method which can detect the possibility of cancer in the initial stage with high accuracy. The canceration information providing method for providing information pertaining to canceration of cells includes: acquiring measurement data including first data pertaining to size of a cell nucleus and second data pertaining to size of a cytoplasm for each cell contained in a measurement sample which includes cells collected from epithelial tissue; extracting the measurement data of cells to be analyzed, which are at least some of the cells located toward the basal membrane side of the cells existing in the surface layer in the epithelial tissue, from the measurement data of a plurality of cells in the measurement sample based on the first data and the second data acquired for each cell; and analyzing the extracted measurement data and outputting the information pertaining to the canceration of cells..
07/17/14
20140199700
new patent Method for producing intestinal cells
An object of the present invention is to provide a method of producing intestinal cells by use of pluripotent stem cells as a starting material. According to the present invention, provided is a method of producing intestinal cells, comprising the steps of: (a) inducing differentiation of pluripotent stem cells into definitive endoderm cells; and (b) culturing the definitive endoderm cells in the presence of (2′z,3′e)-6-bromoindirubin-3′-oxime (bio) and n-[(3,5-difluorophenyl)acetyl]-l-ala-2-phenyl-l-gly-tert-butyl-oh (dapt) to thereby induce differentiation of the definitive endoderm cells into intestinal cells..
07/17/14
20140199693
new patent Method of analysing a blood sample of a subject for the presence of a disease marker
The present invention relates to a method of analysing a blood sample of a subject for the presence of a disease marker, said method comprising the steps of a) extracting nucleic acid from anucleated blood cells in said blood sample to provide an anucleated blood cells-extracted nucleic acid fraction, and b) analysing said anucleated blood cells-extracted nucleic acid fraction for the presence of a disease marker, wherein said disease marker is a disease-specific mutation in a gene of a cell of said subject, or wherein said disease marker is a disease-specific expression profile of genes of a cell of said subject.. .
07/17/14
20140199680
new patent Disposable fluid circuits and methods for cell washing
Systems and methods for the washing and processing of biological fluid/biological cells are disclosed. The systems and methods utilize a disposable fluid circuit including a spinning membrane separation device to wash the biological cells..
07/17/14
20140199679
new patent Bioreactor
A bioreactor for the formation of mature blood cells from haematopoietic stem cells is disclosed. The bioreactor comprises a first zone and a second zone.
07/17/14
20140199618
new patent Methods of measuring overlay errors in area-imaging e-beam lithography
One embodiment relates to a method of measuring overlay errors for a programmable pattern, area-imaging electron beam lithography apparatus. Patterned cells of an overlay measurement target array may be printed in swaths such that they are superposed on patterned cells of a first (base) array.
07/17/14
20140199613
new patent Proton-conducting composite membrane for fuel cells
The present invention relates to a membrane that includes a porous polymer material made of a polyimide with interconnected macropores and impregnated with protic ionic liquid conductors (clip), as well as to the method for manufacturing same and to the uses thereof. The membranes of the invention fulfil the need for membranes including clips, which have good proton-conducting properties as well as good physical properties, in particular high thermal and mechanical stability, in addition to a wide range of electrochemical stability..
07/17/14
20140199611
new patent Proton-conducting membrane, method for their production and their use in electrochemical cells
The present invention relates to a novel proton-conducting polymer membrane based on polyazole polymers which, owing to their outstanding chemical and thermal properties, can be used widely and are suitable in particular as polymer electrolyte membrane (pem) for producing membrane electrode assemblies or so-called pem fuel cells.. .
07/17/14
20140199610
new patent Proton-conducting membrane, method for their production and their use in electrochemical cells
The present invention relates to a novel proton-conducting polymer membrane based on polyazole polymers which, owing to their outstanding chemical and thermal properties, can be used widely and are suitable in particular as polymer electrolyte membrane (pem) for producing membrane electrode assemblies or so-called pem fuel cells.. .
07/17/14
20140199609
new patent Electrocatalyst for solid polymer fuel cell
Provided is an electrocatalyst for solid polymer fuel cells capable of increasing the active surface area for reactions in a catalyst component, increasing the utilization efficiency of the catalyst, and reducing the amount of expensive precious metal catalyst used. Also provided are a membrane electrode assembly that uses this electrocatalyst and a solid polymer fuel cell.
07/17/14
20140199592
new patent High sulfur content copolymers and composite materials and electrochemical cells and optical elements using them
The present invention relates generally to high sulfur content polymeric materials and composites, methods for making them, and devices using them such as electrochemical cells and optical elements. In one aspect, a polymeric composition comprising a copolymer of sulfur, at a level in the range of at least about 50 wt % of the copolymer, and one or more monomers each selected from the group consisting of ethylenically unsaturated monomers, epoxide monomers, and thiirane monomers, at a level in the range of about 0.1 wt % to about 50 wt % of the copolymer..
07/17/14
20140199591
new patent Pasted nickel hydroxide electrode and additives for rechargeable alkaline batteries
A pasted positive nickel hydroxide electrode for use in battery cells (e.g., in nickel zinc cells, and nickel metal hydride cells) includes nickel hydroxide particles, a cobalt metal and/or cobalt compound and a sulfur-containing complexing agent capable of forming a complex with cobalt. The presence of the sulfur-containing complexing agent, such as dialkyldithiocarbamate (e.g., sodium diethyldithiocarbamate) improves lifetime and capacity utilization of the nickel electrode.
07/17/14
20140199585
new patent Low symmetry molecules and phosphonium salts, methods of making and devices formed there from
Synthesis of molecules and salts is disclosed having low average symmetry and their use in many applications, including but not limited to: as electrolytes in electronic devices such as memory devices including static, permanent and dynamic random access memory, as electrolytes in energy storage devices such as batteries, electrochemical double layer capacitors (edlcs) or supercapacitors or ultracapacitors, electrolytic capacitors, as electrolytes in dye-sensitized solar cells (dsscs), as electrolytes in fuel cells, as a heat transfer medium, high temperature reaction and/or extraction media, among other applications. In particular, synthesis methods and processes to form molecules and salts having low average symmetry using mixed grignard reagents are disclosed..
07/17/14
20140199580
new patent Electronic device
To provide an electronic device having high capacity and high reliability. To provide an electronic device with a small size which can be provided indoors even when it has high capacity.
07/17/14
20140199574
new patent Battery and motor vehicle comprising said battery
A battery includes at least one battery module that has several battery cells arranged next to each other on a support plate. The battery module is arranged with the support plate on a base plate of the battery or on a base plate of a lower unit of the battery.
07/17/14
20140199573
new patent Battery pack
A battery pack is disclosed. In one aspect, the battery pack includes a battery cell comprising first and second sides opposing each other, a first cell holder coupled to the first side of the battery cell and a second cell holder coupled to the second side of the battery cell.
07/17/14
20140199570
new patent Battery pack
A battery pack which includes a plurality of contact portions in a terminal accommodating portion provided in each of cell receiving portions of a plurality of battery cells, so that one selected from the plurality of contact portions can be electrically connected to electrode terminals of the battery cells even if the plurality of battery cells have different widths of wide walls. In addition, since the battery pack includes a series/parallel switch provided outside an external pack, a connection method of a plurality of battery cells provided inside the external pack can be switched to series/parallel connection.
07/17/14
20140199569
new patent Predicted sensor information for a battery
A computer-implemented method for predicting a value of a cell parameter is provided, wherein the cell is one of a plurality of cells of a battery pack. The method includes determining which other different conditions of the cell and which similar and/or different conditions of any other cell of the plurality of cells correlate with the cell condition, determining values of one or more parameters from the same cell or any other cell of the plurality of cells that correspond to the determined conditions that correlate with the cell condition, and predicting the value of the cell parameter based on the determined values..
07/17/14
20140199514
new patent Reinforced structural member and frame structures
Disclosed are frame members and mullions for a window frame that comprise a reinforcing member that is surrounded by an outer plastic layer. The outer plastic layer is held securely to the reinforcing member as a result of a waist banding effect that comprises an inward force created by the outer plastic layer as it cools and contracts around the reinforcing member.
07/17/14
20140199415
new patent Pharmaceutical combination comprising a cip2a silencing agent for use in the treatment of a hyperproliferative disorder, preferably one with impaired p53 function
The invention is based on a finding that silencing cip2a (ki-aa1524) gene sensitizes cancer cells for apoptosis-inducing activity of certain small molecule chemotherapeutic agents. Thus, the invention is directed to a respective combination therapy, sensitization method and pharmaceutical compositions.
07/17/14
20140199379
new patent Compositions having means for targeting at least one antigen to dendritic cells
A composition that can be used as a vaccine containing means for targeting at least one antigen to dendritic cells and as adjuvants a granulocyte macrophage colony stimulating factor and a cpg oligodeoxynucleotide and/or a cpg-like oligodeoxynucleotide. This composition can used to treat cancers, infectious diseases caused by bacterial, viral, fungal, parasitic or protozoan infections, allergies and/or autoimmune diseases..
07/17/14
20140199377
new patent Multiple growth factor compositions, methods of fabrication, and methods of treatment
Disclosed are compositions with sustained-release carriers associated with at least two different types of growth factors and methods of fabrication and treatments thereof. In some embodiments, simultaneous release of the growth factors may be preferred while in other embodiments, sequential release of the growth factors may be preferred.
07/17/14
20140199363
new patent Bone-regeneration material
The invention relates to a process for producing a bone-regeneration material. According to the method, a bio-compatible, open-pored body is exposed to a vacuum and osteoinductive and/or osteogenic substances are absorbed into the pores of the body, for example by means of a vacuum generated therein.
07/17/14
20140199348
new patent Anti-viral compounds
Disclosed herein are compounds and related compositions for the treatment of viral infection, including rna viral infection, and compounds that can modulate the rig-i pathway in vertebrate cells, including compounds that can activate the rig-i pathway.. .
07/17/14
20140199345
new patent Immunostimulatory oligodeoxynucleotides
The present invention relates to immunostimulatory oligodeoxynucleotides, vectors and vaccines comprising such oligodeoxynucleotides, to their use as a medicament, to their use in preventing or combating infectious disease, to methods for the detection of such oligodeoxynucleotides and to cells to be used in these methods.. .
07/17/14
20140199344
new patent Anti-measles cancer immunotherapy
The present invention provides methods for treating specific populations of cancer patients by immunotherapy. The methods comprise administering an immunogenic composition eliciting an immune response to measles virus to patients having measles virus-immunoreactive cancer cells..
07/17/14
20140199340
new patent Tolerogenic synthetic nanocarriers for inducing regulatory b cells
Disclosed are synthetic nanocarrier methods, and related compositions, comprising b cell and/or mhc class ii-restricted epitopes and immunosuppressants in order to generate tolerogenic immune responses, such as the generation of antigen-specific regulatory b cells.. .
07/17/14
20140199330
new patent Protein involved in detection of cancer metastasis and a treatment thereof
Using phosphoproteomics, we profiled the phosphorylation levels of hundreds of proteins concurrently across an isogenic model of breast cancer metastasis. Among them is trpv4, a calcium channel that we found to be overexpressed in invasive breast tumors compared to ductal carcinoma in situ, a pre-neoplastic lesion and normal tissues.
07/17/14
20140199327
new patent Methods of promoting differentiation
Provided herein are methods of promoting cell fate change, particularly differentiation of tumor cells, by inhibition of usp1, uaf1, and/or id (e.g., id1, id2, and/or id3).. .
07/17/14
20140199319
new patent Methods for increasing the efficiency of hybridoma generation
Disclosed herein are methods for improving the efficiency of the production of hybridomas, e.g., through enrichment of igg expressing b cells. Also disclosed are hybridoma compositions produced using these methods as well as methods for producing antibodies with the hybridomas..
07/17/14
20140199315
new patent Sp35 antibodies and uses thereof
Endogenous sp35 is a negative regulator for neuronal survival, axon regeneration, oligodendrocyte differentiation and myelination (negative regulator). Molecules that block endogenous sp35 function, such anti-sp35 antibodies can be used as therapeutics for the treatment of neuron and oligodendrocyte dysfunction.
07/17/14
20140199313
new patent Process for the production of fine chemicals
The present invention relates to a process for the production of the fine chemical in a microorganism, a plant cell, a plant, a plant tissue or in one or more parts thereof, preferably in plastids. The invention furthermore relates to nucleic acid molecules, polypeptides, nucleic acid constructs, vectors, antibodies, host cells, plant tissue, propagation material, harvested material, plants, microorganisms as well as agricultural compositions and to their use..
07/17/14
20140199312
new patent Ddr1-binding agents and methods of use thereof
The present invention relates to ddr1 binding agents and methods of using the agents for treating diseases such as cancer. The present invention provides antibodies that specifically bind to an extracellular domain of ddr1 and modulate ddr1 activity.
07/17/14
20140199311
new patent Pharmaceutical composition for treatment and/or prophylaxis of cancer
This invention provides an antibody targeting a cancer antigenic protein specifically expressed on the surface of cancer cells and use thereof as a therapeutic and/or preventive agent for cancer. More specifically, the present invention provides an antibody, or a fragment thereof which has immunological reactivity with a caprin-1 protein, the antibody comprising a heavy chain variable region comprising complementarity determining regions of seq id nos: 5, 6, and 7 and a light chain variable region comprising complementarity determining regions of seq id nos: 9, 10, and 11, and a pharmaceutical composition for treatment and/or prevention of cancer, comprising the same as an active ingredient..
07/17/14
20140199310
new patent Compositions comprising agents that inhibit neuropilin and tolloid like 2
We disclose agents that inhibit the expression of neto-2 which has elevated expression in cancer stem cells; the use of neto-2 as a diagnostic or prognostic marker of tumour initiation; the use neto-2 polypeptides in the identification of agents that inhibit activity; and including antibodies that bind neto-2 and vaccines comprising neto-2 polypeptides.. .
07/17/14
20140199308
new patent Compositions and methods to enhance the immune system
The invention relates to the field of molecular medicine. In particular, it relates to compositions and methods to enhance the clearance of aberrant cells, e.g.
07/17/14
20140199307
new patent Dosage regimen for administering a cd19xcd3 bispecific antibody to patients at risk for potential adverse effects
The present invention relates to a method for assessing (analyzing) the risk of potential adverse effects for a human patient mediated by the administration of a cd19xcd3 bispecific antibody to said patient comprising determining the ratio of b cells to t cells of said patient, wherein a ratio of about 1:5 or lower is indicative for a risk of potential adverse effects for said patient or determining the total b cell count of said patient, wherein a total b cell count of less than about 50 b cells per microliter of peripheral blood is indicative for a risk of potential adverse effects for said patient. Accordingly, the present invention relates a method (dosage regimen) for administering a cd19xcd3 bispecific antibody to a human patient having a b:t cell ratio of about 1:5 or lower and/or a total b cell count of less than about 50 b cells per microliter of peripheral blood, comprising (a) administering a first dose of said antibody for a first period of time; and consecutively (b) administering a second dose of said antibody for a second period of time, wherein said second dose exceeds said first dose.
07/17/14
20140199299
new patent Combination therapies and methods using anti-cd3 modulating agents and anti-il-6 antagonists
This invention relates generally to compositions that contain multiple modulating agents, e.g., multiple modulating agents that target cd3 on t cells and neutralize one or more biological activities of interleukin-6 (il-6), such as cd3 modulators including anti-cd3 antibodies and anti-il-6 antagonists including anti-il-6 antibodies, anti-il-6r antagonists including anti-il-6r antibodies, and/or anti-il-6/il-6r complex antagonists including anti-il-6/il-6r binding antibodies, and methods of using these compositions in the treatment, amelioration and/or prevention of relapse of an autoimmune disease.. .
07/17/14
20140199280
new patent Modulation of bio-electrical rhythms via a novel engineering approach
The present invention relates to novel compositions and methods to induce, and/of modulate bio-electrical rhythms (e.g. In cardiac, neuronal and pancreatic cells) by fine-tuning the activity of hcn-encoded pacemaker channels via a novel protein- and genetic-engineering approach to augment or attenuate the associated physiological responses (e.g.
07/17/14
20140199279
new patent Methods for enhancing the delivery of gene-transduced cells
The present invention provides novel methods for enhancing the delivery of transduced cells to a subject, which include both methods of selecting for transduced cells and methods of enhancing the reconstitution by transduced cells in a transplant recipient. The present invention further provides transfer vectors, including lentiviral vectors, useful in practicing the methods of the present invention.
07/17/14
20140199278
new patent Brown adipocyte modification
Methods and therapeutics are provided for treating metabolic disorders by increasing activation of brown adipose tissue. Generally, the methods and therapeutics can increase activation of brown adipose tissue to increase energy expenditure and induce weight loss.
07/17/14
20140199277
new patent Methods of treatment of retinal degeneration diseases
The methods comprise administering cells having properties of stem cells or progenitor cells, to the retina and reprogramming of retinal cells mediated by cell fusion of said cells with said retinal cells, said reprogramming being mediated by activation of the wnt/β-catenin signalling pathway.. .
07/17/14
20140199276
new patent Inkjet printing of tissues and cells
Provided herein is an apparatus for printing cells which includes an electrospinning device and an inkjet printing device operatively associated therewith. Methods of making a biodegradable scaffold having cells seeded therein are also provided.
07/17/14
20140199275
new patent Treating tear film disorders with mesenchymal stem cells
This invention provides methods of preventing, reducing or inhibiting one or more symptoms of a tear film disorder by administration to a subject mesenchymal stem cells.. .
07/17/14
20140199274
new patent Neuronal progenitor cells and uses
Provided are methods of isolating a novel cell population of midbrain dopaminergic neuronal progenitor cells derived from stem cells using a novel combination markers. The cell population may be used for cell therapies for the treatment of parkinson's disease and as substrates in pharmacological assays..
07/17/14
20140199273
new patent Methods for diagnosis, prognosis and methods of treatment
The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population.
07/17/14
20140199138
new patent Semiconductor wafer handling transport
Modular wafer transport and handling facilities are combined in a variety of ways deliver greater levels of flexibility, utility, efficiency, and functionality in a vacuum semiconductor processing system. Various processing and other modules may be interconnected with tunnel-and-cart transportation systems to extend the distance and versatility of the vacuum environment.


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