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Cells patents



      
           
This page is updated frequently with new Cells-related patent applications. Subscribe to the Cells RSS feed to automatically get the update: related Cells RSS feeds. RSS updates for this page: Cells RSS RSS


Date/App# patent app List of recent Cells-related patents
09/25/14
20140289908
 Gene combinations for producing punicic acid in transgenic plants patent thumbnailGene combinations for producing punicic acid in transgenic plants
Transgenic plants with enhanced punicic acid accumulation result from over-expression of pgfadx and pgfad2, and optionally, one or more of pgdgat1, pgdgat2, and pgpdat1. The invention also relates to novel isolated punica granatum diacylglycerol acyltransferases: type 1 (pgdgat1), type 2 (pgdgat2) and phospholipid:diacylglycerol acyltransferases (pgpdat1); polynucleotide sequences encoding the dgats and pdat enzymes; polynucleotide constructs, vectors and host cells incorporating the polynucleotide sequences; and methods of producing and using same..
09/25/14
20140289906
 Compositions having dicamba decarboxylase activity and methods of use patent thumbnailCompositions having dicamba decarboxylase activity and methods of use
Compositions and methods comprising polynucleotides and polypeptides having dicamba decarboxylase activity are provided. Further provided are nucleic acid constructs, host cells, plants, plant cells, explants, seeds and grain having the dicamba decarboxylase sequences.
09/25/14
20140289905
 Polypeptides having xylanase activity and polynucleotides encoding same patent thumbnailPolypeptides having xylanase activity and polynucleotides encoding same
Provided are isolated polypeptides having xylanase activity, catalytic domains and cellulose binding domains, and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. Also provided are nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains..
09/25/14
20140289904
 Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems patent thumbnailPolyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems
Disclosed are novel acyl-coa synthetases and novel acyltransferases, nucleic acid molecules encoding the same, recombinant nucleic acid molecules and recombinant host cells comprising such nucleic acid molecules, genetically modified organisms (microorganisms and plants) comprising the same, and methods of making and using the same. Also disclosed are genetically modified organisms (e.g., plants, microorganisms) that have been genetically modified to express a pks-like system for the production of pufas (a pufa pks system or pufa synthase), wherein the organisms have been modified to express an acyl-coa synthetase, to express an acyl transferase, to delete or inactivate a fatty acid synthase (fas) expressed by the organism, to reduce competition for malonyl coa with the pufa synthase or to increase the level of malonyl coa in the organism, and in one aspect, to inhibit kasii or kasiii.
09/25/14
20140289900
 Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield and/or agricultural characteristics patent thumbnailIsolated polynucleotides and polypeptides, and methods of using same for increasing plant yield and/or agricultural characteristics
Provided are isolated polynucleotides at least 80% identical to seq id nos: 1-479, 813-5173, 8511, 8513, 8515, 8517, 8519, 8521, 8523, 9096-9141 and 9142; and isolated polypeptides at least 80% homologous to an amino acid sequence selected from the group consisting of seq id nos: 624, 480-623, 625-812, 5174-7015, 7017-7021, 7024, 7026-8510, 8512, 8514, 8516, 8518, 8520, 8522, 8524, 9143-9177, such as the polypeptides set forth in seq id no:480-812, 5174-8510, 8512, 8514, 8516, 8518, 8520, 8522, 8524, and 9143-9177, nucleic acid constructs comprising same, transgenic cells and plants expressing same and methods of using same for increasing yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, nitrogen use efficiency, and/or abiotic stress tolerance of a plant.. .
09/25/14
20140289899
 Sugarcane bacilliform viral (scbv) enhancer and its use in plant functional genomics patent thumbnailSugarcane bacilliform viral (scbv) enhancer and its use in plant functional genomics
Identification of new enhancer sequence has significant utility in the plant functional genomics. The sugarcane bacilliform badnavirus (scbv) transcriptional enhancer has been identified.
09/25/14
20140289884
 Nucleotide sequences and corresponding polypeptides conferring improved nitrogen use efficiency characteristics in plants patent thumbnailNucleotide sequences and corresponding polypeptides conferring improved nitrogen use efficiency characteristics in plants
Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells.
09/25/14
20140289882
 Compositions and methods for re-programming cells without genetic modification for repairing cartilage damage patent thumbnailCompositions and methods for re-programming cells without genetic modification for repairing cartilage damage
The present inventions are directed to compositions and methods regarding the reprogramming of other cells (such as embryonic stem cells (escs), induced pluripotent stem cells (ipscs), mscs, fibroblasts, hematopoietic stem cells, endothelian stem cells, adipocytes, chondrocytes, osteoblasts, osteoclasts and endothelial cells) into chondrogenic cells without introducing exogenous genes to the samples. In particular, the present inventions are directed to transducible materials that are capable of transducing into the biological samples but are not genes or causing genetic modifications.
09/25/14
20140289772
 Dynamic determination of presentation of multiple video cells in an on-screen display patent thumbnailDynamic determination of presentation of multiple video cells in an on-screen display
A mosaic video channel displayed on a monitor, with a plurality of individual video feeds being presented at a given time. A mosaic video channel in accordance with the present invention comprises a plurality of video cells presenting at least video information, each video cell associated with one of the plurality of individual video feeds, a cursor, which can be moved between the plurality of video cells, for selecting at least one characteristic associated with a selected video cell, such that the user can then directly select a video program associated with the selected video cell, and a receiver, coupled to the monitor and receiving the plurality of video feeds and mosaic video channel, wherein a blackout criteria is dynamically programmed into the receiver such that when at least one of the video cells is selected by the cursor, the receiver tunes to a channel other than the individual video feed associated with that video cell..
09/25/14
20140289691
 Circuit design support apparatus, circuit design support method, and computer product patent thumbnailCircuit design support apparatus, circuit design support method, and computer product
A circuit design support apparatus includes a processor that is configured to generate area information that indicates a plurality of areas obtained by dividing a predetermined area in a circuit by a constant interval; generate first layout data that indicates arrangement of buffer cells capable of supplying clock signals to other cells, at least one buffer cell being disposed in each of the areas indicated by the area information; generate based on the first layout data, second layout data that indicates arrangement of the buffer cells and arrangement of flip-flop cells disposed in the predetermined area; and output the second layout data.. .
09/25/14
20140289685
Dynamic power driven clock tree synthesis (cts)
Dynamic power driven clock tree synthesis is described. Some embodiments can select one or more cells from a cell library based on power ratios of cells in the cell library.
09/25/14
20140289601
Method for controlling electronic spreadsheet on handheld touch device
The present invention relates to a method for controlling an electronic spreadsheet on a handheld touch device, comprising an operation procedure, a display procedure and a recovery procedure. The operation procedure comprises: receiving a selection touch control signal for selecting cells, determining selected cells in an electronic spreadsheet according to the selection touch control signal, calculating according to a preset processing method, and storing the calculation result.
09/25/14
20140289600
Manipulating of labelled data for data entry in management applications
A method and system for entry of data into content of cells belonging to an output field. Entered into cells of a multidimensional table located within a header record in the table are: input field labels respectively corresponding to input fields in the table entered into a respective unique cell within the header record; and an output label corresponding to the output field entered into a specifically unique cell within the header record and expressed as a mathematical expression of input field labels.
09/25/14
20140289588
Memory system
A memory system (10) is disclosed, which comprises a flash-eeprom nonvolatile memory (11) having a plurality of memory cells that have floating gates and in which data items are electrically erasable and writable, a cache memory (13) that temporarily stores data of the flash-eeprom nonvolatile memory (11), a control circuit (12, 14) that controls the flash-eeprom nonvolatile memory (11) and the cache memory (13), and an interface circuit (16) that communicates with a host, in which the control circuit functions to read data from a desired target area to-be-determined of the flash-eeprom nonvolatile memory and detect an erased area to determine a written area/unwritten area by using as a determination condition whether or not a count number of data “0” of the read data has reached a preset criterion count number.. .
09/25/14
20140289569
Semiconductor storage device, controller, and memory system
According to one embodiment, a semiconductor storage device includes a memory cell array, a plurality of first latch circuits, a first register and a comparator. The memory cell array has a plurality of memory cells associated with columns.
09/25/14
20140289505
Boot partitions in memory devices and systems
The present disclosure includes boot partitions in memory devices and systems, and methods associated therewith. One or more embodiments include an array of memory cells, wherein the array includes a boot partition and a number of additional partitions.
09/25/14
20140289179
Analog multiplier using a memristive device and method for implemening hebbian learning rules using memrisor arrays
A device, comprising: an array of cells, wherein the cells are arranged in columns and rows; wherein each cell comprises a memristive device; an interfacing circuit that is coupled to each cell of the array of cells; wherein the interfacing circuit is arranged to: receive or generate first variables and second variables; generate memristive device input signals that once provided to memristive devices of the array will cause a change in a state variable of each of the memristive devices of the cells of the array, wherein the change in the state variable of each of the memristive devices of the cells of array reflects a product of one of the first variables and one of the second variables; provide the memristive device input signals to memristive devices of the array; and receive output signals that are a function of at least products of the first variables and the second variables;. .
09/25/14
20140288661
Bone tissue engineering by ex vivo stem cells ongrowth into three-dimensional trabecular metal
Adult autologous stem cells cultured on a porous, three-dimensional tissue scaffold-implant for bone regeneration by the use of a hyaluronan and/or dexamethasone to accelerate bone healing alone or in combination with recombinant growth factors or transfected osteogenic genes. The scaffold-implant may be machined into a custom-shaped three-dimensional cell culture system for support of cell growth, reservoir for peptides, recombinant growth factors, cytokines and antineoplastic drugs in the presence of a hyaluronan and/or dexamethasone alone or in combination with growth factors or transfected osteogenic genes, to be assembled ex vivo in a tissue incubator for implantation into bone tissue..
09/25/14
20140288645
Cell migration inhibition system
Generally, an intraocular implant and methods for treating an ocular condition. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye..
09/25/14
20140288642
Artificial valved conduits for cardiac reconstructive procedures and methods for their production
Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit.
09/25/14
20140288615
First time right placement of a dbs lead
The disclosure is directed to a deep brain stimulation (dbs) lead having a distal end for providing therapeutic electrical stimulation to tissue in a stimulation target area of a patient's brain, comprising an array of one or more stimulation elements and sensing elements located at the distal end of the lead; each of the one or more stimulation elements is capable of providing electrical stimulation to the brain tissue in the target area; and each of the one or more sensing elements is capable of detecting electrical signals produced by nerve cells within the brain; wherein after the first implantation of the lead into the brain along a trajectory that is pre-determined by non-surgical procedures, the array of stimulation and sensing elements is capable of facilitating the location of the target area and the determination for each of the stimulation elements of the required stimulation parameters needed to provide the therapeutic stimulation to the brain tissue in the stimulation target area, without requiring any additional implantations of the lead after the first implantation. A stimulation system including the dbs lead and a pulse generator is disclosed.
09/25/14
20140288611
Zero blood flow sensitive heart stimulator
A zero flow responsive heart stimulator contains a zero flow sensors, which generate signals at the moment of the termination of blood inflow in the right atrium and the right ventricle, sensing this the most precisely in the places, where the sinoatrial node and atrioventricular node reside, for the right atrium and the right ventricle, respectively. The stimulator is based on our discovery, that the two nodes are the same sensors in the biological systems, based on the fact that until the filling of the said two chambers continues, the venous blood flow sucks on bernoulli's principle the ca and na cations from the two nodes interstices, preventing the inward currant in their cells, thus delaying the completion of the 0-phase of their depolarization and the action potential, until the blood flow stops.
09/25/14
20140288434
Optical speculum
A system for direct imaging and diagnosing of abnormal cells in a target tissue includes a disposable optical speculum and an image acquisition system having the speculum assembled on and mechanically secured thereto. The image acquisition system is arranged to capture at least one of a single image or multiple images or video of cells within the target tissue using at least one of bright field or dark field ring illumination divided into independently operated segments to obtain a plurality of data sets.
09/25/14
20140288433
Uv imaging for intraoperative tumor delineation
A medical imaging system and method. A uv/visible camera uses a back illuminated silicon imaging detector to observe a surface of a brain of a subject in vivo during brain surgery for excision of a cancerous tumor.
09/25/14
20140288331
Process for preparing metal difluorochelatoborates and use as battery electrolytes or additives in electrochemical cells
The invention relates to a process for preparing metal difluorochelatoborates, in which a metal bis(chelato)borate of the formula m[bl2] is reacted with boron trifluoride and a metal fluoride (mf) and/or a metal salt of the chelating ligand (m2l) where m+ is a monovalent cation selected from the group consisting of lithium, sodium, potassium and ammonium nr4+, where r═h, alkyl (c1 to c8) and l is a chelating agent having two terminal oxygen atoms and having the general formula (ii), where: when m=1 and y1 and y2 together with c1 form a carbonyl group, n=0 or 1 and o=0 or 1 and r1 and r2 are each, independently of one another, h or alkyl having from one to eight carbon atoms (c1-c8) and y3, y4 are each, independently of one another, or3 (r3═c1-c8-alkyl), then n or o≠1: p=0 or 1 and when n and o=0, p=1; or y1, y2, y3, y4 are each, independently of one another, or3 (r3═c1-c8-alkyl), m=1, n=0 or 1, o=1 and p=0; or c2 and c3 are members of a 5- or 6-membered aromatic or heteroaromatic ring (with n, o or s as heteroelement) which can optionally be substituted by alkyl, alkoxy, carboxy or nitrile, where r1, r2, y3 and y4 are absent, m=0 or in the case of 1, y1 and y2 together with c1 form a carbonyl group and p is 0 or 1, in an organic, aprotic solvent.. .
09/25/14
20140288320
Thioesterases and cells for production of tailored oils
The invention features plant acyl-acp thioesterase genes of the fatb class and proteins encoded by these genes. The genes are useful for constructing recombinant host cells having altered fatty acid profiles.
09/25/14
20140288300
Drug-fluorophore complex for specific detection of tumor cells
Disclosed is a drug-fluorophore complex for specific detection of tumor cells. Specifically, the drug-fluorophore complex includes a tumor cell-targeting drug penetrating tumor cells and non-tumor cells at different rates or levels, and a fluorescent substance chemically bonded to the tumor cell-targeting drug.
09/25/14
20140288293
Compositions and methods for nucleic acid extraction
Compositions and methods for the efficient extraction, enrichment and isolation of nucleic acids from fresh, fixed or fixed and embedded cells, tissues, biological materials and cellular source material.. .
09/25/14
20140288287
Sequence-determined dna fragments encoding trehalose-6p phosphatase proteins
The present invention provides dna molecules that constitute fragments of the genome of a plant, and polypeptides encoded thereby. The dna molecules are useful for specifying a gene product in cells, either as a promoter or as a protein coding sequence or as an utr or as a 3′ termination sequence, and are also useful in controlling the behavior of a gene in the chromosome, in controlling the expression of a gene or as tools for genetic mapping, recognizing or isolating identical or related dna fragments, or identification of a particular individual organism, or for clustering of a group of organisms with a common trait..
09/25/14
20140288281
Production of glycoproteins with low n-glycolylneuraminic acid (neu5gc) content
The present invention relates to a medium for the cultivation of eukaryotic cells, the medium comprising as (an) additive(s) dmso, n-acetylmannosamine (nacman), n-acetylglucosamine (nacglc), or any combination of two or more of these additives, including the combination of nacman and nacglc.. .
09/25/14
20140288274
Human monoclonal antibody neutralizing vascular endothelial growth factor receptor and use thereof
The present invention relates to human monoclonal antibodies neutralizing vascular endothelial growth factor receptor and the use thereof. More specifically, relates to human scfv molecules neutralizing vascular endothelial growth factor receptor, and a composition for inhibiting angiogenesis and a composition for treating cancer, which contain the human scfv molecules.
09/25/14
20140288272
Antibody purification and purity monitoring
Processes for producing and purifying recombinant proteins are disclosed. In particular, the present disclosure provides processes of producing and purifying multi-subunit proteins expressed in yeast or filamentous fungal cells.
09/25/14
20140288267
Compositions and methods for modulating rsv infection and immunity
Compositions and methods are provided for the treatment or prevention of rsv disease by modulating rsv infection and immunity. In particular, amino acid sequences in the rsv g glycoprotein, containing the chemokine motif defined as c-x-x-x-c (or cx3c), are identified that are essential in causing rsv infection and disease.
09/25/14
20140288182
Use of carbamide peroxide injection in preparation of virus inactivation medicaments for treating diseases
The invention relates to the field of medicament use, in particular to the clinical use of carbamide peroxide injection series for virus inactivation in the treatment of blood vessel plaque, leukemia, aids and hepatitis, etc. The invention utilizes the affinity of photosensitizers to blood vessel plaque focus, leukemia cells, tumor, and/or virus, which is several times higher than that to normal tissues, so as to destroy focus cells or virus by generating sufficient singlet oxygen (1o2) under the effect of a method using laser, x-ray, ultrasound and medicament, etc., while in condition of using carbamide peroxide injection series.
09/25/14
20140288162
Methods, compositions and screens for therapeutics for the treatment of synovial sarcoma
Methods and compositions are provided for treating human synovial sarcoma (ss). Also provided are screens to identify therapeutics for the treatment of synovial sarcoma.
09/25/14
20140288161
Urocortin-iii and uses thereof
A search of the public human genome database identified a human est, genbank accession number aw293249, which has high homology to known pufferfish urocortin sequences. The full length sequence was amplified from human genomic dna and sequenced.
09/25/14
20140288160
Cleavable lipids
Disclosed herein are novel compounds, pharmaceutical compositions comprising such compounds and related methods of their use. The compounds described herein are useful, e.g., as liposomal delivery vehicles to facilitate the delivery of encapsulated polynucleotides to target cells and subsequent transfection of said target cells, and in certain embodiments are characterized as having one or more properties that afford such compounds advantages relative to other similarly classified lipids..
09/25/14
20140288147
Methods of manipulating the fate of cells
A method of manipulating the fate of a cell which comprises contacting the cell with at least one of (a) a cell fate-determining untranslated/noncoding rna species (cur), (b) a modified cur, or (c) a compound that modifies or affects cur, under condition sufficient to cause a cell-changing or cell-maintaining fate that results in cell regeneration, cell differentiation or cell death, so that an increase of desirable cells or a decrease in undesirable cells can be obtained. Another aspect of the invention relates to a method of manipulating the fate of a cell by contacting the cell with a compound that affects a fate-determining mechanism involving homologous nucleic acid interactions of rna:rna or rna:dna or resolution of such interactions under conditions sufficient to cause a cell-changing or cell-maintaining fate that results in cell regeneration, cell differentiation or cell death, so that an increase of desirable cells or a decrease in undesirable cells can be obtained.
09/25/14
20140288146
Novel trialkyl cationic lipids and methods of use thereof
The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel cationic lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo.
09/25/14
20140288145
Treatment of amyloidosis by compounds that regulate retromer stabilization
The present invention provides pharmaceutical compositions and related methods for stabilizing retromer in cells.. .
09/25/14
20140288135
Aminoalkyloxazole and aminoalkylthiazolecarboxylic acid amides as regeneration-promoting substances for sensory organs and post-mitotic tissues
A method of treating inner ear hardness of hearing and restoring hearing of humans and animals after damage and loss of sensory hair cells in an organ of corti based on regeneration biology includes administering a therapeutically effective amount of a compound including aminoalkyloxazole and aminoalkylthiazole carboxylic acid amides, or a pharmaceutically acceptable salt, a stereoisomer, a stereoisomer mixture, a tautomer or a prodrug compound thereof, directly or indirectly to damaged tissue structures in a cochlea, optionally, by transtympanal injection into a middle ear, by application to a round or oval window of an inner ear or by injection into the inner ear.. .
09/25/14
20140288098
Bruton's tyrosine kinase as anti-cancer drug target
Receptor protein kinases (rptks) transmit extracellular signals across the plasma membrane to cytosolic proteins, stimulating formation of complexes that regulate key cellular functions. Over half of the known tyrosine kinases are implicated in human cancers and are therefore highly promising drug targets.
09/25/14
20140288087
Niche targeting of quiescent cancer stem cells
The disclosure provides methods for determining the self-renewal potential of a cancer stem cell (csc), or for predicting the drugability (susceptibility to a drug) of a csc, and/or for predicting the progression of a cancer that corresponds to the csc. In alternative embodiments, the disclosure provides methods for determining whether a csc in a niche is more pro-apoptotic or more anti-apoptotic in relation to a normal stem cell or a csc from another niche.
09/25/14
20140288078
Use of phosphodiesterase inhibitors for treating multidrug resistance
The present invention relates to methods of treating multidrug resistance in cancerous cells with phosphodiesterase (pde) inhibitors, e.g., pde5 inhibitors. More specifically, the invention relates to methods of treating multidrug resistance that arises, e.g., during administration of chemotherapeutic/antineoplastic (anticancer) agents for treatment of cancer, with a pde5 inhibitor (e.g., sildenafil, vardenafil, and tadalafil).
09/25/14
20140288047
Benzoxazepin pi3k inhibitor compounds and methods of use
Benzoxazepin compounds of formula i, including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, wherein: z1 is cr1 or n; z2 is cr2 or n; z3 is cr3 or n; z4 is cr4 or n; and b is a pyrazolyl, imidazolyl, or triazolyl ring fused to the benzoxepin ring, are useful for inhibiting lipid kinases including p110 alpha and other isoforms of pi3k, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of formula i for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed..
09/25/14
20140288018
Methods for predicting the response to anti-cancer treatment with an agonist of tlr7 or an agonist of tlr8
The present invention relates to methods for predicting the response to treatment with an agonist of tlr7, or an agonist of tlr8 or an anti-cancer agent for treating cancer, in particular non-small cell lung cancer comprising the step of detecting the expression of tlr7 or tlr8 in cancer cells of said patient.. .
09/25/14
20140288010
Compositions and methods for increasing stem cell survival
Compositions and methods of increasing autophagy in a cell, or population of cells are disclosed. The methods generally include contacting the cell or cells with an effective amount of an agent that increases the bioavailability of an active isoform of sdf-1.
09/25/14
20140288009
Collagen-like silk genes
The present invention relates to silk proteins which can be used to produce silk with a collagen-like structure, as well as nucleic acids encoding such proteins. The present invention also relates to recombinant cells and/or organisms which synthesize silk proteins.
09/25/14
20140288003
Inhibition of collagen synthesis
Therapies and compositions for reducing collagen synthesis in mammalian cells and tissues wherein the targets are scleraxis, scleraxis-binding sites, receptor-regulated smads, and/or binding sites for receptor-regulated smads whereby synergistic interactions between scleraxis proteins and receptor-regulated smads are reduced, inhibited, interfered with, stopped, and/or prevented thereby reducing, inhibiting and/or interfering with the activation of collagen 1α2 promoter thereby inhibiting collagen production in mammalian cells and tissues. Alternatively, the therapies and compositions may reduce, inhibit, interfere with, stop, and/or prevent binding of the collagen 1α2 promoter to dna thereby inhibiting expression of the collagen 1α2 gene in mammalian cells and tissues..


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