|| List of recent Cells-related patents
| Phacosporacea resistant soybean plants|
The present invention relates to a method of increasing resistance against fungal pathogens of the family phacosporaceae in transgenic plants and/or plant cells. In these plants, the ethylene signaling pathway and/or activity of the ethylene signaling compounds is changed.
| Application of ossro1c gene in controlling rice drought resistance|
Rice ossro1c gene conferring enhanced drought resistance of a plant is provided, wherein the said gene encodes an amino acid sequences as set forth in seq id no: 2. Dna constructs, transgenic plants or cells comprising the ossro1c gene and the uses of the ossro1c gene in improving though resistance of a plant are also provided.
| Chimeric promoters capable of mediating gene expression in plants upon pathogen infection and uses thereof|
Described are synthetic promoters capable of mediating gene expression in plants upon pathogen infection. Furthermore, recombinant genes and vectors comprising said chimeric promoters as well as host cells transformed with such chimeric promoters, recombinant genes, or vectors are provided.
| Error protection for integrated circuits|
A method for providing error detection and/or correction to an array of storage cells includes determining a sensitive direction and an insensitive direction of the storage cells and adding a first error control mechanism to the array of storage cells in the insensitive direction. The method also includes adding a second error control mechanism to the array of storage cells in the sensitive direction.
| At-speed scan testing of clock divider logic in a clock module of an integrated circuit|
An integrated circuit comprises scan test circuitry and additional circuitry subject to testing utilizing the scan test circuitry. The scan test circuitry comprises a scan chain having a plurality of scan cells.
| Systems and methods for accessing memory|
Methods of mapping memory cells to applications, methods of accessing memory cells, systems, and memory controllers are described. In some embodiments, a memory system including multiple physical channels is mapped into regions, such that any region spans each physical channel of the memory system.
| Determining soft data for fractional digit memory cells|
Apparatuses and methods for determining soft data for fractional digit memory cells are provided. One example apparatus can include a controller to determine states of memory cells of a group of memory cells operated as fractional digit memory cells, and determine soft data based, at least partially, on dimensions to which particular memory cells correspond with respect to the group of memory cells, determined states of the memory cells with respect to a state adjacent a state corresponding to a swapping shell, and whether a particular memory cell is a candidate for swapping..
| Semiconductor device and method of operating the same|
A method of operating a semiconductor device may comprise storing data in memory cells coupled to first word lines of memory blocks including the first word lines and second word lines located respectively between the first word lines, detecting a memory block, where data stored in the memory cells of the first word lines is invalidated, from the memory blocks, and storing data in memory cells coupled to the second word lines of the detected memory block.. .
| Management of and region selection for writes to non-volatile memory|
Management of and region selection for writes to non-volatile memory of an ssd improves performance, reliability, unit cost, and/or development cost of an ssd. A controller receives and determines characteristics of writes (e.g.
| Multilevel cell nonvolatile memory system|
A multilevel cell (mlc) nonvolatile memory system including a plurality of memory cells each cell storing first bit data and second bit data, and a controller programming the plurality of memory cells on a page-by-page basis, the controller programming original data to an original block and programming copy data that is the same as the original data to a mirroring block, wherein first bit page data and second bit page data of the original data are programmed to memory cells connected to the same word line, but the first bit page data and second bit page data of the copy data are programmed to memory cells connected to different word lines.. .
| Methods and system for image guided cell ablation with microscopic resolution|
The invention provides systems and method for the removal of diseased cells during surgery. .
| Method for infusing stem cells|
A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface.
| Led induced tattoo removal system and method of use|
An led induced tattoo removal system and method of use that utilizes an ultra bright led having a principal peak with a peak at 640 nm-700 nm for tattoo removal without causing collateral skin damage and without causing pain to a subject is disclosed. The tattoo removal method includes an led, which generates light in a specific range of wavelengths proven to be effective for this purpose.
| Method for diagnosing cancer|
Wherein r1, r2, r3, r4, r5, r6, r7, r8, and r9 are as defined above; wherein fluorescence emitted by a compound of formula (ii) is indicative of the presence of cancerous cells or tissue.. .
| Magnetic field measurement apparatus|
A magnetic field measurement apparatus includes a probe beam irradiating unit that radiates a probe beam. A gas cell is arranged on an optical axis of the probe beam and shows a linear dichroism with respect to the probe beam between a first axis and a second axis.
| Deep tissue flowmetry using diffuse speckle contrast analysis|
Blood flow rates can be calculated using diffuse speckle contrast analysis in spatial and time domains. In the spatial domain analysis, a multi-pixel image sensor can be used to detect a spatial distribution of speckles in a sample caused by diffusion of light from a coherent light source that is blurred due to the movement of scatterers within the sample (e.g., red blood cells moving within a tissue sample).
| Method and apparatus for in vivo collection of circulating biological components|
The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis.
| Targeting micrornas for the treatment of liver cancer|
Provided herein are methods for the treatment of liver cancer. These methods encompass the administration of a compound comprising a modified oligonucleotide, wherein the modified oligonucleotide is targeted to a mirna.
| Proteins from the webs of nephilengys cruentata, avicularia juruensis and parawixia bistriata spiders isolated from brazilian biodiversity|
The present invention relates to molecules isolated from the nucleic acid that encodes spider web proteins or fragments of these or other derivatives of these. The invention also refers to a chimerical gene and an expression vector containing molecules isolated from the nucleic acid that codes for proteins related to the webs of nephilengys, cruentata, avicularia juruensis and parawixia bistriata spiders.
| Therapeutic trail fusion protein and preparation and use thereof|
This invention relates to the biotechnology area, and provides a kind of trail chimeric protein, dna sequence encoding this chimeric protein, vectors comprising this dna, host cells or transgenic animals that contain one of the vectors, and preparation methods for the said chimeric protein and its applications. The said trail fusion protein from the n to c terminal comprises human leucine zipper sequence, human trail protein, human trail extracellular domain or a fragment thereof.
| Fluorescent labeling of living cells|
Wherein each of the variables are as defined herein.. .
| Novel n- and c-terminal substituted antagonistic analogs of gh-rh|
There is provided a novel series of synthetic analogs of hgh-rh(1-29)nh2 (seq id no: 1) and hgh-rh(1-30)nh2. Of particular interest are those carrying phac, n-me-aib, dca, ac-ada, fer, ac-amc, me-nh-sub, phac-ada, ac-ada-d-phe, ac-ada-phe, dca-ada, dca-amc, nac-ada, ada-ada, or ch3—(ch2)10—co-ada, at the n-terminus and β-ala, amc, apa, ada, ae2a, ae4p, ε-lys(α-nh2), agm, lys(oct) or ahx, at the c-terminus.
| Mrm/srm assay for death receptor 5 protein|
Specific peptides, and derived ionization characteristics of those peptides from death receptor 5 (dr5) protein are provided that are particularly advantageous for quantifying the dr5 protein directly in biological samples that have been fixed in formalin by the method of selected reaction monitoring/multiple reaction monitoring (srm/mrm) mass spectrometry. Such biological samples are chemically preserved and fixed wherein the biological sample is selected from tissues and cells treated with formaldehyde containing agents/fixatives including formalin-fixed tissue/cells, formalin-fixed/paraffin embedded (ffpe) tissue/cells, ffpe tissue blocks and cells from those blocks, and tissue culture cells that have been formalin fixed and or paraffin embedded.
| Srm/mrm assay for the fatty acid synthase protein|
Specific peptides, and derived ionization characteristics of the peptides, from the fatty acid synthase (fasn) protein are provided that are particularly advantageous for quantifying the fasn protein directly in biological samples that have been fixed in formalin by the method of selected reaction monitoring (srm) mass spectrometry, or what can also be termed as multiple reaction monitoring (mrm) mass spectrometry. Such biological samples are chemically preserved and fixed and are selected from tissues and cells treated with formaldehyde containing agents/fixatives including formalin-fixed tissue/cells, formalin-fixed/paraffin embedded (ffpe) tissue/cells, ffpe tissue blocks and cells from those blocks, and tissue culture cells that have been formalin fixed and or paraffin embedded.
| Engineered nucleic acids and methods of use thereof for non-human vertebrates|
Provided are formulations, compositions, kits and methods for delivering biological moieties such as modified nucleic acids into cells to induce, reduce or modulate protein expression in non-human vertebrates.. .
| Methods for producing interfering rna molecules in mammalian cells and therapeutic uses for such molecules|
Methods for producing interfering rna molecules in mammalian cells are provided. Therapeutic uses for the expressed molecules, including inhibiting expression of hiv, are also provided..
| Method of enhancing lysosomal alpha-galactosidase a|
A method of enhancing the activity of lysosomal α-galactosidase a (α-gal a) in mammalian cells and for treatment of fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds.. .
| Lpa2 receptor-specific benzoic acid derivatives|
Disclosed are compounds effective for inhibiting cellular apoptosis and for protecting cells and tissues from the apoptotic effects of chemotherapeutic agents and/or ionizing radiation. Compounds of the invention act as agonists of the lpa2 receptor.
| Methods and compositions for inhibiting cellular proliferation and surgical adhesion|
The present invention provides compositions and methods to inhibit fibrosis and scarring associated with surgery. The present invention relates to the discovery that a synthetic anionic polymer consisting of dextran-sulfate (anionic carbohydrate) conjugated to tirofiban (an anti-platelet agent which prevents platelet activation and aggregation) can effectively inhibit adhesions that form during surgery.
| Stromal derived factor inhibition and cxcr4 blockade|
The invention relates to inhibition of sdf-1α expression in subacromial bursa cells by cxcr-4 inhibitors. Bursal cell migration in response to sdf-α stimulation is also decreased in the presence of cxcr4 inhibitors.
| T cell receptors and related materials and methods of use|
The invention provides t cell receptors (tcrs) having antigenic specificity for a cancer antigen, e.g., tyrosinase. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, and pharmaceutical compositions.
| Peptide for inducing regeneration of tissue and use thereof|
(means for solution) multiple peptides were synthesized, and the migration-promoting activity of each peptide was evaluated. As a result, the present inventors successfully identified multiple peptides that have migration-promoting activity on a pdgfrα-positive bone marrow mesenchymal stem cell line (msc-1).
| Polypeptides having protease activity and polynucleotides encoding same|
The present invention relates to isolated polypeptides having protease activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
| Ovarian markers of follicular maturity and uses thereof|
The present invention relates to field of fertility. The invention identifies biological ovarian markers from follicular cells, from follicular fluid, from cumulus cells and from oocytes which are indicative of follicular maturity in mammals.
| Esophageal cancer markers|
The present invention is directed to methods for diagnosing cancer in a subject. Morphologically normal epithelial cells of the esophagus are assayed for marker expression.
| Assay for metastatic potential of tumor cells|
The present invention relates to methods, compositions and kits related to a novel in vitro assay for a high-capacity and high-throughput method for measuring the ability of cancer cells to migrate in a three-dimensional cellular assay. The three-dimensional cellular invasion assay provides a method for determining and quantitating the metastatic potential and invasive capacity of a cancer cell.
| Methods for preimplantation genetic diagnosis by sequencing|
The present disclosure provides methods for determining the ploidy status of an embryo at a chromosome from a sample of dna from an embryo. The ploidy state is determined by sequencing the dna from one or more cells biopsied from the embryo, and analyzing the relative amounts of each allele at a plurality of polymorphic loci on the chromosome.
| Method of measuring adaptive immunity|
A method of measuring immunocompetence is described. This method provides a means for assessing the effects of diseases or conditions that compromise the immune system and of therapies aimed to reconstitute it.
| Method of measuring adaptive immunity|
A method of measuring immunocompetence is described. This method provides a means for assessing the effects of diseases or conditions that compromise the immune system and of therapies aimed to reconstitute it.
| Rnai-based method of screening and characterizing drug combinations|
In one aspect, the invention is directed to a method of characterizing a mechanism of action of a combination of agents. The method comprises contacting a plurality of populations of cells with a combination of agents to be assessed, wherein each population of cells have one gene of interest targeted by a small hairpin rna (shrna) and wherein the gene of interest regulates cell death and a plurality of genes that regulate cell death are targeted in the plurality of populations of cells.
| Apparatus and method for transmitting power headroom information in a multi-carrier system|
A method of transmitting a power headroom by a user equipment (ue) in a multi-carrier system. The method includes: receiving power determination information from a base station (bs); determining a maximum transmission power value for each of a plurality of serving cells by using the power determination information and a ue specific parameter; determining a power heaadroom (ph) for the each of the plurality of serving cells on the basis of the maximum transmission power value for each of a plurality of serving cells; and transmitting control information to the bs, the control information comprising the maximum transmission power value and the ph for the each of the plurality of serving cells, wherein the control information includes information that indicates a specific cell for which the maximum transmission power value and the ph are provided among the plurality of serving cells..
| Generic positioning protocol|
In an aspect, a generic positioning protocol (gpp) may be used to support satellite-based positioning methods and terrestrial-based positioning methods for different access types. A terminal may exchange a first gpp message with first information for a positioning method and an access type supported by gpp.
| Method for inter-radio access technology cell reselection|
A method for performing cell reselection first determines a current cell selection quality value. The cell selection quality value is compared to a predetermined threshold.
| Method and apparatus for providing detection of a compatible network|
An approach is provided for searching and detecting cells. System synchronization sequences are detected.
| Memory cells, integrated devices, and methods of forming memory cells|
Some embodiments include integrated devices, such as memory cells. The devices may include chalcogenide material, an electrically conductive material over the chalcogenide material, and a thermal sink between the electrically conductive material and the chalcogenide material.
| Method of manufacturing see-through thin film solar cells|
A method of manufacturing see-through thin film solar cells includes the steps of: placing a patterned photo mask above a first substrate which has a photoelectric conversion film formed on the surface thereof; and ablating the photoelectric conversion film via a laser beam passing through the patterned photo mask to form at least one hollow-out zone with different transmittance. By incorporating the laser beam with the photo mask in the manufacturing process, the problem of shortened laser lifespan caused by frequent switching of the laser for ablating patterns that occurs to the conventional technique can be resolved.
| Strain induced reduction of switching current in spin-transfer torque switching devices|
Partial perpendicular magnetic anisotropy (ppma) type magnetic random access memory cells are constructed using processes and structural configurations that induce a directed static strain/stress on an mtj to increase the perpendicular magnetic anisotropy. Consequently, reduced switching current of the mtj results.
| Methods for obtaining positive transformants of a filamentous fungal host cell|
The present invention relates to methods for obtaining positive transformants of a filamentous fungal host cell, comprising: transforming a tandem construct into a population of cells of the filamentous fungal host a tandem construct and isolating a transformant of the filamentous fungal host cell comprising the tandem construct. The present invention also relates to such tandem constructs, filamentous fungal host cells comprising such tandem constructs, and methods of producing multiple recombinant proteins..
| Human pluripotent stem cells induced from undifferentiated stem cells derived from a human postnatal tissue|
Establishment of human pluripotent stem cells having properties close to human es cells with the genome of the patient per se that can circumvent immunological rejection of transplanted cells from cells derived from a postnatal human tissue are described. Human pluripotent stem cells can be induced by introducing three genes of oct3/4, sox2 and klf 4, or three genes of oct3/4, sox2 and klf 4 plus the c-myc gene or a histone deacetylase (hdac) inhibitor of undifferentiated stem cells present in various human postnatal tissues in which each gene of tert, nanog, oct3/4 and sox2 has not undergone epigenetic inactivation..
| Composition and method for delivery of living cells in a dry mode having a surface layer|
The present invention generally relates to compositions and methods of delivering living cells in a dry mode, wherein the compositions include a surface layer disposed on the outer surface of the composition that is permeable to carbon dioxide and oxygen. The compositions may be used to deliver living cells to a delivery point without the use of expensive refrigerants such as dry ice or liquid nitrogen..
| Microfluidic system for nucleic acid analysis|
A microfluidic system for analyzing nucleic acid, the microfluidic system including a reagent supply device including a sample chamber into which a sample can be injected, one or more reagent chambers for containing one or more reagents for extracting nucleic acid from the sample, and a waste chamber in which the used reagent can be discarded; a binding-lysis chamber in which cells are captured from the sample and lysed to form a cell lysate containing nucleic acid; plurality of particles for cell binding disposed in the binding-lysis chamber; a plurality of rehydration chambers into which the cell lysate formed in the binding-lysis chamber can be distributed and mixed with a nucleic acid amplification reagent to form an amplification reaction mixture; a plurality of amplification chambers in which a nucleic acid amplification reaction is performed on the amplification reaction mixture introduced from the plurality of rehydration chambers; and a flow channel system including an outlet and a plurality of inlets connected to the reagent supply device and forming an integrated fluid flow between the binding-lysis chamber, the rehydration chambers, and the amplification chambers.. .
| Metabolically engineered yeasts for the production of ethanol and other products from xylose and cellobiose|
The present invention provides yeast cells that produce high concentrations of ethanol, culture media and bioreactors comprising the yeast cells, and methods for making and using the yeast cells in efficiently producing ethanol.. .
| Vector with codon-optimised genes for an arabinose metabolic pathway for arabinose conversion in yeast for ethanol production|
The present invention relates to novel expression cassettes and expression vectors, comprising three nucleic acid sequences for araa, arab and arad, each coding for a polypeptide of an l-arabinose metabolic pathway, in particular, a bacterial l-arabinose metabolic pathway. The invention particularly relates to expression cassettes and expression vectors, comprising codon-optimised nucleic acid sequences for araa, arab and arad.
| Biological synthesis of difunctional alkanes from carbohydrate feedstocks|
Aspects of the invention relate to methods for the production of difunctional alkanes in host cells. In particular, aspects of the invention describe components of genes associated with the difunctional alkane production from carbohydrate feedstocks in host cells.
| Method for purifying bacterial cells|
The present invention relates to a process for providing purified bacteria-containing concentrates, comprising at least the steps of adding an aqueous solution to a first bacteria-containing concentrate to provide a bacteria-containing suspension, wherein the volume of the added aqueous solution is in the range of 0.3 liters to 10 liters per liter of said first bacteria-containing concentrate; and concentrating said bacteria-containing suspension to provide a second bacteria-containing concentrate. Further, the present invention relates to the purified concentrates per se..
| Bioactive carbon nanotube composite functionalized with b-sheet polypeptide block copolymer, and preparation method thereof|
The present invention relates to a bioactive carbon nanotube composite functionalized with a β-sheet polypeptide block copolymer by combination self-assembly, which shows excellent water dispersion, and has biological activity so as to be used as stimulus-responsive and adaptable biomaterials or in the manufacture of cnt-based electronic biosensor devices. In addition, the bioactive carbon nanotube composite can be used as a composition for delivery of a biological active material into cells.
| Methods of synthesizing heteromultimeric polypeptides in yeast using a haploid mating strategy|
Methods are provided for the synthesis and secretion of recombinant hetero-multimeric proteins in mating competent yeast. A first expression vector is transformed into a first haploid cell; and a second expression vector is transformed into a second haploid cell.
| Dna vector production system|
A vector production system is provided. The system comprises recombinant cells designed to encode at least a first recombinase under the control of an inducible promoter and the cells include an expression vector encoding a nucleic acid of interest within the regulatory elements of the expression vector which are flanked on either side by a target sequence for at least the first recombinase.
| Polypeptides having glucoamylase activity and polynucleotides encoding same|
Provided are isolated polypeptides having glucoamylase activity, catalytic domains, and polynucleotides encoding the polypeptides, catalytic domains. Also provided are nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains..
| Method for screening alpha-amylases|
The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants..
| Three-dimensional cell culture methods for test material assessment of cell differentiation|
The present specification discloses three-dimensional in vitro cell-based methods to assess a test matrix polymer ability to support differentiation of a population of cells methods of screening a material for its ability to stimulate cell growth and/or differentiation.. .
| Fc-function assay|
The present invention discloses a method of assaying fc-function in an immunoglobulin containing sample by contacting the sample, in the presence of a complement, with red blood cells modified to incorporate a f-s-l peptide-lipid construct. The f-s-l peptide construct comprises a functional group (f) that is a target antigen for a complement activating immunoglobulin, a spacer group (s) covalently linking f to l and a lipid group (l).
| Method for identifying agents that inhibit cell migration, promote cell adhesion and prevent metastasis|
Disclosed are methods for identification of agents that modulate cell attachment, cell migration and cell viability. Cancer and primary cells adhered to a matrix are treated with agent(s) that modulate actrii signaling and cell adhesion.
| Rationale, methods, and assays for identifying human and non-human primate taste specific genes and use thereof in taste modulator and therapeutic screening assays|
This invention relates to novel rationale and methods for identifying human and primate taste-specific genes, including genes involved in salty taste perception, especially human salty taste perception, but also genes involved in sweet, bitter, umami, and sour taste perception, and genes involved in other taste cell or taste receptor related activities such as digestive function and digestive related diseases, taste cell turnover, immunoregulation of the oral and digestive tract, and metabolic regulation such as in diabetes and obesity, the genes identified using these methods, and assays for identifying taste modulators (enhancers or blockers) and potential therapeutics using these genes. These compounds have potential application in modulating (enhancing or blocking) taste perception, especially salty taste perception and as potential therapeutics.