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Casein patents

      

This page is updated frequently with new Casein-related patent applications.




Date/App# patent app List of recent Casein-related patents
08/18/16
20160235105 
 Novel compositions patent thumbnailNovel compositions
The invention relates to a dry compositions for lactic acid bacteria and in particular to a dry composition comprising from 109 to 1013 cfu/g of the composition of lactic acid bacteria cells, wherein the composition is characterized by that it also comprises following amounts of protective agents (all amounts of protective agents below are given relative to 1 g of lactic acid bacteria cells in the composition): from 6 to 9 g of trehalose, from 0.1 to 1 g of inulin and from 0.5 to 3 g of hydrolyzed casein, and by that it does not comprise a salt of alginic acid. The composition has an improved storage stability of the cell of interest.
Chr. Hansen A/s


07/21/16
20160205960 
 Improved process for the humanization of animal skim milk patent thumbnailImproved process for the humanization of animal skim milk
Claimed is the preparation of an infant formula base product, comprising: (a) microfiltration (me) of animal skim milk over a membrane having a porosity of 0.10-0.35 micrometer and operating with a volume concentration factor of 1.5-8, resulting in a retentate (mfr) and a permeate (mfp); (b) ultrafiltration (uf) of the mep originating from step (a) over a membrane having a molecular weight cut-off of at most 25 kda and operating with a volume concentration factor of 1.5-8, resulting in a retentate (ufr) and a permeate fuep); (c) combining the mfr from step (a) and the ufr from step (b), to obtain a defined casein/whey ratio. Alternatively, the product of step (a) is used as a protein source.
N.v. Nutricia


07/14/16
20160198753 
 Liquid concentrated human milk fortifier containing hypoallergenic protein and lutein patent thumbnailLiquid concentrated human milk fortifier containing hypoallergenic protein and lutein
The present invention is directed to concentrated liquid human milk fortifiers using extensively hydrolyzed casein as a protein source, a stabilizer system comprising octenyl succinic anhydride modified corn starch in combination with a low acyl gellan gum, and the carotenoid lutein.. .
Abbott Laboratories


06/09/16
20160160234 
 Composition for transferring gene to cell patent thumbnailComposition for transferring gene to cell
Disclosed are a composition for gene transfer, a method for introducing a gene into cell of a non-human animal, a method for introducing a gene into an in vitro cell, and a kit for gene transfer. The composition comprises (a) at least one lipid selected from the group consisting of sorbitan sesquioleate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan trioleate, sorbitan monooleate, l-α-phosphatidylinositol, l-α-dioleoyl phosphatidylethanolamine, octadecylamine, hexadecylamine, dotap, and cardiolipin; (b) at least one protein selected from the group consisting of albumin, casein, gelatin, and sericin; and (c) at least one positively charged substance selected from the group consisting of protamine sulfate, polyarginine, polylysine, polyethyleneimine, and hexadimethrine bromide..
Ishihara Sangyo Kaisha, Ltd.


06/02/16
20160151253 
 Method for cleaning tooth surface, composition for cleaning tooth surface, and  using the composition patent thumbnailMethod for cleaning tooth surface, composition for cleaning tooth surface, and using the composition
Provided is a method for cleaning tooth surfaces including: applying a composition for cleaning tooth surfaces to tooth surfaces, the composition including: 1 to 20% by weight of a casein phosphopeptide-amorphous calcium phosphate complex and/or a casein phosphopeptide-amorphous calcium fluoride phosphate complex; 0.001 to 3% by weight of xylitol and/or sodium saccharin; 20 to 80% by weight of a wetting agent; 0.1 to 20% by weight of silica whose average particle size is no less than 0.5 μm and no more than 50 μm; and water as a main component of a reminder; and maintaining a state in which a part of the composition for cleaning tooth surfaces remains in a mouth.. .
Gc Corporation


05/19/16
20160136238 
 Beta-casein a2 and reducing or preventing symptoms of lactose intolerance patent thumbnailBeta-casein a2 and reducing or preventing symptoms of lactose intolerance
Preventing or reducing the symptoms of lactose intolerance in an animal comprising the consumption by the animal of a composition containing beta-casein, or providing the composition to the animal for consumption, where the beta-casein comprises at least 75% by weight beta-casein a2. The effect is both acute (post-exposure to the composition) and ongoing (future exposure to lactose)..
The A2 Milk Company Limited


05/05/16
20160122358 
 Novel substituted pyrazolo-piperazines as casein kinase 1 d/e inhibitors patent thumbnailNovel substituted pyrazolo-piperazines as casein kinase 1 d/e inhibitors
And pharmaceutically acceptable salts thereof. The compounds of formula (i) inhibit protein kinase activity thereby making them useful as anticancer agents..

04/28/16
20160113997 
 Beta-casein a2 and prevention of inflammation of the bowel patent thumbnailBeta-casein a2 and prevention of inflammation of the bowel
The use of a composition for preventing or reducing the risk of inflammation of the bowel in an animal, wherein the composition contains beta-casein and wherein the beta-casein comprises at least 50% by weight beta-casein a2.. .
The A2 Milk Company Limited


04/21/16
20160106684 
 Casein coated drug-loaded iron oxide nanoparticles patent thumbnailCasein coated drug-loaded iron oxide nanoparticles
This disclosure relates to nanoparticle drug delivery systems composed of casein (cn) coated nanoparticles, e.g., iron oxide nanoparticles coated with an inner layer and an out layer comprising the milk protein casein. In certain embodiments, drug molecules are incorporated into an inner polymeric layer coating the nanoparticles, which are subsequently coated with a casein containing outer layer, i.e., a layer-by-layer (lbl) construction.

04/07/16
20160095332 
 High protein food patent thumbnailHigh protein food
A high protein food may be produced via an extrusion process whereby acid casein is mixed with whey protein, alkali and water. Upon exiting the extruder, the mixture may be cut, dried, and/or tempered, milled and screened before being further processed or packaged.
Erie Foods International, Inc.


03/17/16
20160075889 

Biodegradable fire resistant foam


The instant invention is a fire protectant composition comprising water, a surfactant, a water-soluble polymer, casein, and a calcium salt. The compositions can be applied to materials such as wood in advance of a fire, and after application, the compositions are capable of retaining their fire protectant capacities for days, weeks or even months.
Multi, Inc.


03/10/16
20160067376 

Bone substitute nanocomposites and methods of synthesis using multiphosphorylated peptides


The invention relates to peptides including dede(ssd)ndeg indicated by seq no. 1, rrrdede(ssd)ndeg indicated by seq no.
University Of Pittsburgh - Of The Commonwealth Of Higher Education


03/03/16
20160058823 

Composition and use of a dietary supplement


Composition of a dietary supplement, characterised in that it comprises a mixture of at least a-casein tryptic hydrolysate, siberian or asian ginseng root powder, and lyophilised melon extract.. .
New Matrix, Besloten Vennootschap Met Beperkte Aansprakelijkheid


03/03/16
20160058745 

Casein kinase 1delta (ck 1delta) inhibitors


The invention relates to pharmaceutical compositions having casein kinase 1 delta (ck1δ) inhibitors and to the use of the inhibitors in the treatment of neurodegenerative disorders such as alzheimer's disease.. .
Electrophoretics Limited


03/03/16
20160058027 

Powdered composition for use in an instant milk tea powder


A powdered composition which can be produced by spray-drying, and which can be used as the base of an instant milk tea powder is provided. The powdered composition comprises: 25-35% of di-/tri-saccharides other than lactose; 3-20% of lactose; 2-15% milk protein other than processed soluble caseinate; 35-50% fat; and 3-7% emulsifier.
Conopco, Inc., D/b/a Unilever


03/03/16
20160058025 

Method of producing a composition containing caseinomacropeptide


The present invention pertains to a method of producing caseinomacropeptide (cmp)-containing compositions in high yield and having a very low content of phenylalanine (phe). More specifically, the method involves subjecting a whey derived feed to a combination of ultrafiltration and subsequent cation exchange..
Arla Foods Amba


02/18/16
20160044949 

Protein composition and production process therefor


The present invention provides a protein composition comprising a milk basic protein fraction; and at least one stabilizer selected from the group consisting of soybean polysaccharides, xanthan gum, pectin, gum arabic, gum ghatti, carrageenan, locust bean gum, sodium caseinate, lecithin, and carboxymethylcellulose. The protein composition significantly improves the heat resistance of the milk basic protein fraction.
Megmilk Snow Brand Co., Ltd.


02/18/16
20160044933 

Process and system for preparing dry milk formulae


The invention relates to a process for treating animal skim milk and sweet whey and/or acid whey, comprising: (a) ultrafiltration (uf1) of a first liquid composition comprising animal skim milk with 70-90 wt % casein and 10-30 wt % whey proteins, based on total protein, over a first ultrafiltration membrane having a molecular weight cut-off of 2.5-25 kda using a volume concentration factor of 1.5-6 to obtain a retentate (ufr1) and a permeate (ufp1); (b) ultrafiltration (uf2) of a second liquid composition comprising sweet whey and/or acid whey over a second ultrafiltration membrane having a molecular weight cut-off of 2.5-25 kda using a volume concentration factor of 2-15 to obtain a retentate (ufr2) and a permeate (ufp2); and (c) mixing the uf retentate originating from step (a) with the uf retentate originating from step (b) to obtain a mixture of uf retentates.. .
N.v. Nutricia


02/18/16
20160044932 

Process and system for preparing dry milk formulae


A process and system is disclosed for obtaining a dry milk formula, comprising (a-i) ultrafiltration of an animal skim milk composition comprising 70-90 wt % casein and 10-30 wt % whey proteins, based on total protein, and (a-ii) ultrafiltration of an animal whey composition comprising 0-25 wt % casein and 75-100 wt % whey proteins, based on total protein; or (a-iii) ultrafiltration of a mixture of the compositions of (a-i) and (a-ii), (b) removing polyvalent ions from the uf permeate originating from step (a-i) and/or (a-ii) or (a-iii) to obtain at least one softened uf permeate; (c) combining the at least one softened uf permeate with a uf retentate to obtain a combined product; and (d) drying the combined product to obtain a dry milk formula.. .
N.v. Nutricia


02/11/16
20160037815 

Nutritional compositions including calcium beta-hydroxy-beta-methylbutyrate, casein phosphopeptide, and protein


Nutritional compositions that include calcium ?-hydroxy-?-methylbutyrate and protein, and methods of using and making the nutritional compositions are provided. casein phosphopeptide is utilized to sequester the calcium ?-hydroxy-?-methylbutyrate to reduce the interaction between the divalent calcium ions and protein in the nutritional composition to improve the overall stability, shelf life, and viscosity of the nutritional composition, while also facilitating the absorption of calcium..
Abbott Laboratories


02/04/16
20160029645 

Food product having high milk protein content and process of making same


A food product and process of making the same is provided which results in a high milk protein product having 10% to 25% milk protein content, higher phospholipids compared to unadulterated cow milk, a casein to whey ration of at least 50:50 and is shelf stable for at least six months. In the process whole milk and at least one milk protein source is mixed, heated and contacted with an acid or acidulating substance and co-precipitated to produce a semi-solid precipitate.
Cal Poly Corporation


01/28/16
20160025741 

System and the detection of allergens


Methods and systems for detecting allergens using mass spectrometry are provided herein. In some aspects, a sample can be screened for the presence or quantity of ovalbumin, lysozyme, casein (isoform s1 and s2), lactoglobulin, high and low glutens, wheat, rye, oats, barley, mustard, sesame, and various types of nuts including macadamia, pistachio, brazil, walnuts, peanuts and hazelnuts by detecting one or more peptides specific to the allergen of interest using selected mrm transitions..
Dh Technologies Development Pte. Ltd.


01/28/16
20160022843 

Coated magnetic nanoparticles for imaging enhancement and drug delivery


This disclosure is in the area of diagnostics and nanotechnology. This disclosure provides a method for synthesizing casein coated iron oxide nanoparticles to be used as an mri contrasting agent and targeted drug delivery..
Emory University


01/21/16
20160017003 

Process for the production of cyclosporin-a using the fungus tolypocladium sp. strain nrrl no.: 18950


Provided herein is a process for the production of cyclosporin-a (cyc-a) including the steps of inoculating a nutrient medium with the fungus tolypocladium sp., strain nrrl no. 18950 followed by cultivation under static conditions to obtain a fermented medium with the fungal biomass, and harvesting the biomass and subjecting the harvested biomass to extraction followed by purification to obtain pure cyc-a.
Indian Council Of Medical Research


12/17/15
20150359244 

Method of producing beta-casein compositions and related products


The present invention pertains to a method of producing beta-casein-containing compositions and products obtainable by such methods. More particularly, the invention pertains to a method of producing beta-casein compositions using controlled microfiltration first at a temperature higher than 20 degrees c., followed by cooling of the retentate to 0-15 degrees c.
Arla Foods Amba


12/17/15
20150359238 

Powdery yoghurt material and yoghurt making method


Provided are a yoghurt material for making a homemade yoghurt at home and a yoghurt making method using the yoghurt material. The powdery yoghurt material comprises: a milk powder and a lactic acid bacterium fermented at an ordinary temperature, wherein the powdery yoghurt material is converted into a yoghurt when the material to which water was added is fermented.
Nutrition Act. Co., Ltd.


12/10/15
20150352082 

Substituted benzothiazoles and therapeutic uses thereof for the treatment of human diseases


The invention relates to a family of differently substituted benzothiazoles having inhibitory activity against casein kinase 1 (ck-1) enzyme, as a result of which they are suitable for use in the treatment or prevention of diseases caused by this enzyme, particularly diseases associated with circadian rhythm and inflammatory, autoimmune, psychiatric, neurodegenerative, neurological or ophthalmic diseases, as well as for inducing cell regeneration. .
Consejo Superior De Investigaciones CientÍficas


12/10/15
20150351437 

Method for the preparation of a liquid enteral nutritional composition comprising micellar casein


The invention relates to a method for preparing a shelf-stable liquid enteral composition for providing nutrition, either as a supplement, or as a complete nutrition, comprising a high amount of micellar casein, comprising dissolving a dry blend of micellar casein and digestible carbohydrate.. .
N.v. Nutricia


12/10/15
20150351427 

Method for producing meat substitute products


The invention relates to a method for producing meat substitute products, wherein a mixture of water and a vegetable fat/oil comprising a protein, sodium alginate and methylcellulose is processed by shearing/stirring to produce a stable emulsion, and a colloidal solution of divalent metal cations and micellar casein is added to the emulsion for initiating a fibre formation, wherein the quantity of divalent metal cations is selected such that it leads to the initiation of the fibre formation in combination with the micellar casein.. .
Rovita Gmbh


12/03/15
20150344481 

Novel substituted imidazoles as casein kinase 1 d/e inhibitors


The invention provides compounds of formula (i) and pharmaceutically acceptable salts thereof. The compounds of formula (i) inhibit protein kinase activity thereby making them useful as anticancer agents..
Bristol-myers Squibb Company


12/03/15
20150344480 

Pyrazole substituted imidazopyrazines as casein kinase 1 d/e inhibitors


The invention provides compounds of formula (i) and pharmaceutically acceptable salts thereof. The compounds of formula (i) inhibit protein kinase activity thereby making them useful as anticancer agents..
Bristol-myers Squibb Company


12/03/15
20150343010 

Use of a casein hydrolysate as an antiherpetic agent


The present invention relates to the use of a casein hydrolysate as an antiherpetic agent. This casein hydrolysate has an application in both the treatment and the prevention of the reactivation of a latent infection by a herpesvirus, and is effective both orally and topically.
Ntd Labs, S.l.


11/26/15
20150335577 

Microparticles for encapsulating probiotics, production and uses thereof


The invention relates to microparticles comprising a matrix formed by casein and chitosan, and probiotic bacteria; said matrix protects said probiotic bacteria during (i) processing, (ii) storage and (iii) transit through the gastrointestinal tract, prolonging their lifetime. The present invention also relates to the method for obtaining the microparticles and to the products and compositions incorporating them..
Universidad De Navarra


11/26/15
20150335039 

Cheese compositions and related methods


Described are cheese compositions and methods of making cheese compositions, including methods of formulating cheese compositions, wherein the cheese compositions may include combinations of casein protein, fiber, non-casein protein, non-pregelatinized, modified starch, and a fat component.. .
General Mills, Inc.


11/12/15
20150320102 

Low viscosity, high caloric density oral nutritional composition and related methods


Disclosed embodiments provide low viscosity, high caloric density liquid nutritional compositions. The use of non-micellar milk protein in combination with hydrolyzed caseinate and unique formulation methods allow for improved organoleptic qualities and the production of liquid nutritional compositions displaying low viscosity along with a high caloric density..
Abbott Laboratories


11/12/15
20150320067 

Low-fat processed mozzarella cheese and food items containing same


The invention concerns a process for the production of a low-fat mozzarella comprising the steps of preparing a bulking pre-mix of dry components such as one or a mixture of rennet casein, sodium casein, milk protein concentrate and whey protein concentrate, salt, potassium sorbate and/or sorbic acid, sodium aluminium phosphate, sodium citrate, starch, skim milk powder, and stabiliser; adding said pre-mix to water at ambient temperature; raising the temperature to 80 to 85° c. Whilst stirring the mixture; and adding natural mozzarella, sequestering agent, and citric acid monohydrate or lactic acid until the mixture is smooth and homogeneous..

10/29/15
20150307549 

Agent for preventing arteriosclerosis, agent for suppressing vascular intimal thickening and agent for improving vascular endothelial function


Provided is an agent having at least one of an improving effect on vascular endothelial functions and an inhibitory effect on vascular intimal thickening, as well as a prophylactic of arteriosclerosis, which have excellent safety, improve functions associated with the vascular endothelium, have effects of preventing various diseases associated with vascular endothelial functions and of inhibiting vascular intimal thickening, and may be expected to provide prophylactic effect on arteriosclerosis. The agents of the present invention contain, as an active component: (a) xaa-pro-pro, (b) a hydrolysate of animal milk casein containing xaa-pro-pro, or a concentrate thereof, or (c) a fermentation product containing ile-pro-pro and/or val-pro-pro obtained by fermenting a starting material containing milk protein with a bacterial strain of the species lactobacillus helveticus..
Calpis Co., Ltd


10/22/15
20150301049 

Method for diagnosing and treating kidney injury or disease


The protein kinase c and casein kinase 2 substrate in neurons (pacsin) is a subfamily of membrane-binding proteins, participates in vesicle trafficking and cytoskeleton organization. Pacsin 2 expression is significantly upregulated during the repair phase of post ischemia-reperfusion injured (iri) kidneys, especially on the apical brush border of proximal tubules, which experienced massive damage.
The Brigham And Women's Hospital, Inc.


09/17/15
20150259698 

Plants having enhanced yield-related traits and a making the same


The present invention provides a method for enhancing yield-related traits and/or improving various plant growth characteristics by modulating expression in a plant of a nucleic acid encoding a grp (growth regulating protein). The grp is selected from a lob-domain comprising protein (lob: lateral organ boundaries), herein abbreviated as lbd polypeptide, a jmjc (jumonji-c) polypeptide, a cki (casein kinase i) polypeptide, a bhlh11-like (basic helix-loop-helix 11) protein, a plant homeodomain finger-homeodomain (phdf-hd) polypeptide, an asr (abscisic acid-, stress-, and ripening-induced) polypeptide and/or a squamosa promoter binding protein-like 11 (spl11) transcription factor polypeptide.
Basf Plant Science Gmbh


09/03/15
20150245644 

Composition of nutrients and bioactive substances which promote growth and reduce intolerance and side effects in premature infants


The present disclosure is related to the obtaining of a nutritional formula for the feeding of preterm born infants. The formula comprises a mixture of casein; whey milk protein; alphalactalbumin; beta casein a2 protein, lactose; palmitic acid in beta position; non digestible oligosaccharides; long chain polyunsaturated fatty acids (lc pufas); nucleotides; vitamins and minerals; inositol, choline, taurine and carnitine in concentrations sufficient enough to satisfy nutritional requirements of premature children, besides being better-tolerated..
Nucitec, S.a. De C.v.


08/20/15
20150231157 

Casein micelles for nanoencapsulation of hydrophobic compounds


The present invention relates to the field of food technology and delivery of hydrophobic biologically active compounds, particularly nutrients, via food products and beverages. In particular the present invention provides isolated casein micelles useful for the encapsulation of hydrophobic nutrients, therapeutic and cosmetic compounds, compositions thereof and methods of preparing the micelles..
Technion Research And Development Foundation Ltd.


08/06/15
20150218426 

High performance water-based adhesion compositions and applications


An adhesion composition comprising a) a first polymer that is selected from the group consisting of acrylic polymers, acrylonitrile butadiene, butyl rubber, cellulose acetate, cellulose butyrate, epoxy resins, ethylene vinyl acetate, natural rubber, neoprene, phenolic polymers, polyurethanes, polyvinyl acetate, polyvinyl alcohol, styrene butadiene rubber, casein, dextrin, starch, copolymers thereof and combinations thereof; b) a second polymer selected from the group consisting of ethylene-acrylic acid copolymer, oxidized polyethylene, oxidized ethylene-vinyl acetate copolymer, maleated polyolefin and combinations thereof; and c) a surfactant; where the composition is water-based, having a solids content of greater than about 30% based on the total weight of the composition, with a particle size of about 10 nm to about 2000 nm, and is adapted for adhesion to substrates; and where the first and second polymers are different. The adhesion composition can also comprise a tackifier resin selected from the group consisting of rosin ester resin, rosin acid resin, synthetic hydrocarbon resin, synthetic terpenic resin and combinations thereof.
Honeywell International Inc.


08/06/15
20150216213 

Liquid nutritional formula for phenylketonuria patients


This is a process to make a shelf-stable, liquid, ready-to-drink, aseptic nutritional formula for the treatment of pku, tyrosinemia or other errors of metabolism. The liquid nutritional formula has caseino-glyco-macropeptide as the primary protein source and complementary essential amino acids to complete the requirement profile.
Cambrooke Therapeutics, Inc.


07/30/15
20150209368 

Casein kinase 1delta (ck 1delta) inhibitors


The invention relates to pharmaceutical compositions having casein kinase 1 delta (ck1δ) inhibitors and to the use of the inhibitors in the treatment of neurodegenerative disorders such as alzheimer's disease.. .
Electrophoretics Limited


07/30/15
20150209354 

Casein kinase 1 inhibitors for the treatment of b-cell chronic lymphocytic


Leukemia. .
medicaments for the treatment of the b-cell chronic lymphocytic leukemia, which are inhibitors of casein kinase 1.


07/23/15
20150201638 

Food products and systems and methods of making same


Food products and systems and methods for their production involve microfiltration (“mf”) of fluid skim to form a mf retentate, combining the mf retentate with cream and subjecting the combination to ultrafiltration (“uf”) to form a uf retentate. Prior to uf, the composition is formed of non-acidified components.
Land O'lakes, Inc.


07/16/15
20150196633 

Hypo-allergenic cross-linked proteins for use in the prevention of an allergy against milk-proteins and for use in the induction of oral tolerance


The present invention provides a hypo-allergenic cross-linked protein for use in the prevention of an allergy against milk proteins, or for use in the induction of oral tolerance for milk proteins, said cross-linked protein being selected from cross-linked casein, cross-linked caseinate and combinations thereof. The invention further provides a nutritional composition for use in the prevention of an allergy against milk proteins or for use in the induction of oral tolerance against milk proteins..
Friesland Brands B.v.


06/25/15
20150174080 

Nutritional composition for promoting musculoskeletal health in patients with inflammatory bowel disease (ibd)


A nutritional composition for promoting musculoskeletal health in patients with inflammatory bowel disease is disclosed. The nutritional composition comprises casein protein, vitamin k in a ratio of vitamin k1:vitamin k2 being between 3:1 to 1:3 and the vitamin k providing between 3.5-20 μg/100 kcal of the nutritional composition, vitamin d and alpha-linolenic acid.
Nestec S.a.


06/25/15
20150173396 

Casein products and c02 reversible acidification methods used for their production


The invention provides methods for improving at least one physicochemical property of a product comprising casein micelles, the method comprising applying carbon dioxide to an aqueous product comprising casein micelles to reduce the ph of the product; increasing the ph of the product; and collecting the product comprising casein micelles, in which at least some of the casein micelles of the product are modified in structure by one or more of steps a) and b) compared to naturally occurring casein micelles thereby improving at least one physicochemical property of the product comprising casein micelles. The method reduces viscosity and improves mouth feel of reconstituted product, reduces rehydration time for dried product, improves cheese manufacturing by reducing rennetting or clotting time in cheese manufacture or reducing the amount of rennet required in cheese manufacture..
Murray Goulburn Co-operative Co. Limited


06/18/15
20150164985 

Method for producing a protein and lipid comprising composition with reduced digestive coagulation


The present invention relates to a process of producing a composition comprising at least two different proteins, of which at least one is a casein and at least one is an anti-coagulating protein, comprising the steps of: a) heat-sterilising a first liquid component which comprises said casein in an amount of at least 85 wt % of the total protein content of the first component, b) heat-sterilising a second liquid component comprising said anti-coagulating protein, and c) mixing said first component with said second component to obtain a mixture thereof. The obtained mixture is useful as a food constituent having reduced coagulation in the upper gastro-intestinal tract, more in particular in the stomach..
N.v. Nutricia


06/18/15
20150164122 

High energy liquid enteral nutritional composition


High energy and high protein liquid nutrition enteral compositions are provided that contain micellar casein and caseinate, an optionally a small amount of whey.. .
N.v. Nutricia


06/04/15
20150150274 

Milk products with increased water binding


The present invention relates to a casein concentrate wherein the milk protein comprises not more than 10% serum protein, and wherein the casein micelles have an average size of less than 175 nm in diameter; and wherein the concentrate has a ph below 6,7. Treating milk so as to shift the equilibrium out of the casein micelles and towards the serum phase modifies the micelles so as to allow increased water binding by the casein concentrate.
Arla Foods Amba


05/28/15
20150148283 

Novel casein protein product


The present invention relates to a process for producing a casein protein product comprising the steps of:—providing a casein concentrate starting material,—heat-treating the material,—cooling the heat-treated material,—subjecting the cooled material to a treatment with a crosslinking enzyme,—optionally subjecting the cooled material to a treatment with a coagulant and—processing the material into the casein protein product/allowing the casein protein product to form.. .
Valio Ltd


05/28/15
20150147555 

Multilayer mucoadhering patch with a nonadhering layer comprising casein


A multilayer, mucoadhering patch, comprising a first, exposed layer of adhesive material including a polymer that is capable of adhering to a wet mucous surface in a human or other animal; and a second, exposed layer of nonadhesive material comprising casein.. .
Orahealth Corporation


05/28/15
20150147367 

Method for nanocapsulation of hydrophobic compounds and compositions thereof


Nanoencapsulation of hydrophobic compounds using native casein micelles by means of ph changes and ultrasonication.. .
Tarbiat Modaress University


05/21/15
20150140169 

Enzyme variants


The invention relates to a polypeptide having chymosin activity which: a. Is capable of hydrolysing bovine alpha s1-casein at position f23f24 so as to form αs1-i cn (f24-199) more rapidly than camel chymosin; and b.
Dsm Ip Assets B.v.


05/14/15
20150133428 

Novel substituted pyrazolo-piperazines as casein kinase 1 d/e inhibitors


And pharmaceutically acceptable salts thereof. The compounds of formula (i) inhibit protein kinase activity thereby making them useful as anticancer agents..

05/14/15
20150128329 

Polymeric compositions comprising polyisoprene


A glove, including a polymeric, elastomeric, or latex composition, having a water-based emulsion of a polyisoprene polymer; a first accelerator comprising at least one of a thiourea, a benzothiazole sulphenamide, a thiazole, or a dialkyl dithiocarbamate, or combinations thereof, a second accelerator comprising a thiuram or a xanthogen, or a combination thereof, at least one anti-oxidant, at least one vulcanizing agent; and an activator, wherein a total amount of the first accelerator and the second accelerator ranges from 0.2 to 2.5 phr of the polymeric, elastomeric, or latex composition and the polymeric, elastomeric, or latex composition is substantially free of diphenyl guanidine and/or casein.. .

04/30/15
20150118675 

Immunochromatography detection method


The present invention provides an immunochromatography detection method capable of suppressing non-specific reactions. The present invention relates to an immunochromatography detection method including: a step of adding an analyte dilution solution containing an analyte to a chromatography medium; a step of recognizing a detection target by a labeling substance modified with gold nanoparticles, which is dry-retained at a labeling substance retaining part; a step of developing a composite of the labeling substance and the detection target as a mobile phase; and a step of detecting the detection target in the developed mobile phase at a judgment part, wherein the labeling substance is protected with a polyalkylene glycol having one or more mercapto groups and/or a derivative thereof and then dry-retained together with arginine and casein at the labeling substance retaining part..
Tanaka Kikinzoku Kogyo K.k.


04/23/15
20150111832 

Pharmaceutical combination for the treatment and/or chemosensibilization of refractory tumors to anticancer drugs


This invention is related to a pharmaceutical combination that contains a casein kinase 2 (ck2) peptide inhibitor (termed p15) along with the standard chemotherapeutic drugs used in cancer treatment and which are administered together, separated or sequentially. The chemotherapeutic drugs include cisplatin, taxol, alkaloids from vinca, 5-fluorouracil, doxorubicin, cyclophosphamide, etoposide, mitomycin c, imatinib, iressa, velcade (bortezomib), cytarabine (ara c), fludarabine and mitroxantrone.
Centro De Ingenieria Genetica Y Biotecnologia


04/02/15
20150093459 

Bioactive complex compositions and methods of use thereof


A bioactive complex composition having enhanced oxidative stability, emulsion stability, mineral rich transparent beverages and a wide range of functional health benefits. The composition may include as a base composition individual ingredients or a synergistic blend of mineral salts, omega-3 rich oils, phospholipids, chitosan, and alpha-casein, beta-casein, kappa-casein or protein fragments, glycopeptides, phosphopeptides.
Texas A&m University System


03/26/15
20150086648 

Methods for treating heat stress and related compositions


Methods of treating, reducing, and/or preventing heat stress are provided. For example, provided is a method of treating or preventing heat stress in a subject comprising selecting a subject in need of heat stress treatment or prevention and administering an effective amount of one or more of astaxanthin and milk casein hydrolysate, or a derivative thereof to the subject.
Georgetown University


03/19/15
20150079231 

Method for inhibiting aggregate formation during protein hydrolysis


Disclosed is for inhibiting gel formation during, or resulting from, hydrolysis of protein compositions comprising casein.. .
Glanbia Nutritionals (ireland) Plc


02/19/15
20150051097 

Methods for screening inhibitors of tau phosphorylation by casein kinase i


Methods of screening for candidate compounds capable of inhibiting activity of fyn in phosphorylating tau protein at y394 or binding to fyn to inhibit interaction with tau protein at y394, including determining whether, and optionally the extent, the candidate compounds have these capabilities under conditions where fyn has these capabilities in the absence of the candidate compound. Methods of screening for substances capable of promoting dephosphorylation of tau protein by a phosphatase at a site of tau protein including contacting a candidate substance, the tau protein and a phosphatase capable of dephosphorylating the tau protein under conditions where the phosphatase is capable of dephosphorylating the site in absence of the candidate substance, where the kinase is fyn; determining whether, and optionally the extent, the candidate substance promotes dephosphorylation of the tau protein at the site; and selecting the candidate substance which promotes dephosphorylation of the tau protein the sites..
King's College London


02/12/15
20150045304 


The invention relates to peptides including dede(ssd)ndeg indicated by seq no. 1, rrrdede(ssd)ndeg indicated by seq no.
University Of Pittsburgh - Of The Commonwealth System Of Higher Education


02/12/15
20150045294 

Energy-rich liquid nutritional composition having improved organoleptic properties


The object of the present invention is to provide a liquid enteral composition for providing nutrition, either as a supplement, or as a complete nutrition, comprising a high protein content, in particular micellar casein as major protein source, in a small volume of liquid, in particular 6 to 20 g protein per 100 ml of the liquid composition, the composition further comprising lactic acid and having a ph in the range of 6 to 8. It is also an object of the invention to provide an improved manufacturing process for such liquid enteral compositions..
N.v. Nutricia


01/29/15
20150031078 

Kluyveromyces lactis yeast strain and methods for the production of sugars, ethanol, beta-galactosidase and biomass


The present invention is a kluyveromyces lactis yeast strain comprising the sequence identified by seq id no: 1, and methods for the production of sugars (glucose and galactose), ethanol, β-galactosidase and biomass, in which said kluyveromyces lactis yeast strain is cultured in the presence of a lactose-containing medium. The lactose-containing medium may be milk, whey, whey resulting from the preparation of butter, whey resulting after casein precipitation, milk permeate, whey permeate, acid whey and ypl culture medium..
Queizuar, S.l.


01/29/15
20150030700 

Pharmaceutical combination for the treatment and/or chemosensibilization of refractory tumors to anticancer drugs


This invention is related to a pharmaceutical combination that contains a casein kinase 2 (ck2) peptide inhibitor (termed p15) along with the standard chemotherapeutic drugs used in cancer treatment and which are administered together, separated or sequentially. The chemothearapeutic drugs include cisplatin, taxol, alkaloids from vinca, 5-fluorouracil, doxorubicin, cyclophosphamide, etoposide, mitomycin c, imatinib, iressa and velcade (bortezomib).
Centro De Ingenieria Genetica Y Biotecnologia


01/29/15
20150030687 

Use of fermented milk product for skin treatment


The use of a fermented milk product comprising non-hydrolysed whey proteins which is substantially free of casein proteins for the purpose of improving skin firmness, by structuring collagen without promoting collagen synthesis, when topically applied to skin is provided.. .
Quest International Services B.v.


01/08/15
20150011468 

Uses of casein compositions


casein compositions for increasing the rate of gastric emptying following ingestion of the composition, increasing the digestibility of a protein composition, or increasing the rate of delivery of amino acids to the blood, or for increasing the blood serum concentration of free leucine in a subject, preferably to substantially the same level as whey protein, the casein being about 10 to about 100% calcium depleted, having a degree of hydrolysis less than about 1% and having an unmodified phosphorylation pattern.. .
Fonterra Co-operative Group Limited


12/18/14
20140370155 

Stabilized concentrated liquid human milk fortifier


Disclosed are shelf-stable concentrated liquid human milk fortifiers including extensively hydrolyzed casein. The long term shelf stable, concentrated liquid human milk fortifiers include octenyl succinic acid (osa) modified waxy potato starch as a stabilizer..
Abbott Laboratories


12/18/14
20140370153 

Concentrated low water activity liquid human milk fortifier including extensively hydrolyzed protein


Disclosed are concentrated liquid human milk fortifiers including extensively hydrolyzed casein, and optionally a probiotic. The concentrated liquid human milk fortifier has a low water activity and a low ph, thereby reducing microbial growth in the fortifier..
Abbott Laboratories


12/11/14
20140363819 

Composition to overcome inhibitors in pcr and growth cultures


Provided herein are compositions and methods for improving amplification or detection of a target nucleic acid in a sample containing pcr inhibitors, such as polyphenols. One aspect provides an enhancer composition including casein or polyvinylpyrrolidone, or a modified polymer thereof.

11/27/14
20140349327 

Method for producing fructosyl valyl histidine oxidase preparation


A method for producing a fvho preparation comprising a step of allowing at least one member selected from phosphoric acid, casein peptone, d-glucosamine hydrochloride, melibiose, sorbose, lactose, fructose, melezitose, glucono-1,5-lactone, and ribitol; and a method for producing a dried fvho preparation, comprising a step of allowing bicine to coexist.. .

11/06/14
20140328970 

Nutritional composition comprising whey and hydrolyzed casein and uses thereof


The present disclosure provides a nutritional composition, such as a preterm infant formula that includes a protein source comprising whey protein and hydrolyzed casein protein. The whey protein to hydrolyzed casein ratio may be from about 90:10 to about 50:50 by weight.

10/16/14
20140308398 

Protein fortified yogurts and methods of making


Methods of making protein-fortified yogurt products are described. The methods may include mixing a casein-containing ingredient with starting milk to make a yogurt milk, where the casein-containing ingredient has a casein-to-whey protein ratio of 82:18 or greater.

10/16/14
20140308393 

Reduced calorie infant formulas containing specific whey to casein ratios


The present disclosure is directed to nutrition systems including at least a first and a second reduced calorie infant formula having varying whey to casein protein weight ratios for reducing inflammation-related diseases later in life. Particularly, the nutrition systems may be administered to a newborn infant to reduce the risk of obesity later in life..

10/16/14
20140308369 

Dietary product intended to reduce visceral fat during the pre-operative phase prior to bariatric surgery


An orally administered dietary product intended to reduce an obese person's visceral fat during the pre-operative phase prior to bariatric surgery, the product includes in particular a mixture of: a whey hydrolysate having a molecular weight of between 200 and 10,000 daltons, an isolate and/or a concentrate of whey, and calcium caseinate.. .

10/09/14
20140302224 

Protein seasonings and methods of making the same


A protein seasoning and methods of making the same are provided. A formulation can be provided comprising a base combined with a protein source, which can be combined with various flavored seasonings/ingredients to form protein seasonings that can be added to different foods and/or liquids.

10/09/14
20140302219 

Method for producing a milk product


A method is disclosed for producing an infant formula base, wherein by means of microfiltration, ultrafiltration, and nanofiltration the components of milk are separated into a casein fraction, a whey protein fraction, and a lactose fraction to produce, by suitably combining, a composition in which the amino acid composition is close to that of human milk. An infant formula base having a total protein concentration of about 1.0 to about 1.5% and a β-casein concentration of at least about 11% of the total protein concentration is also disclosed.

09/25/14
20140287057 

Dietary product intended for the prevention of cardiometabolic risk


A dietary product for preventing cardiometabolic risk in humans, in particular for reducing visceral fat and deep subcutaneous fat, includes in particular a mixture of: a whey hydrolysate having a molecular weight of between 200 and 10,000 daltons, an isolate and/or concentrate of whey, and calcium caseinate.. .

09/25/14
20140284272 

Methods for the bioremediation of petroleum in an aquatic environment


In one embodiment, a bioremediation agent and method of bioremediation of an oil spill are disclosed. The bioremediation agent contains oil-digesting bacteria and bacterial nutrients in a buoyant water semi-insoluble and biodegradable casein product.

09/18/14
20140274892 

Reducing the risk of autoimmune disease


The present disclosure provides a method for reducing the risk of autoimmune disease by administering a composition comprising peptides selected from a casein hydrolysate. Such a composition, may reduce the symptoms of autoimmune disease and may be a treatment for autoimmune disease, especially type 1 diabetes.

09/18/14
20140272074 

Crumble process cheese products and methods of production


Crumble process cheese products may be produced by cooling process cheese to freezing temperatures below about 32° f. And holding the process cheese at the freezing temperatures for a sufficient amount of time to cause a freeze-induced denaturation of the protein bonds in the process cheese, thereby providing a modified process cheese with a texture adapted to crumble.

09/18/14
20140271555 

Activating adiponectin by casein hydrolysate


The present disclosure provides a method for activating adiponectin by administering a composition comprising peptides selected from a casein hydrolysate. Such a composition may reduce risk of heart attack and help in maintaining healthy weight.

09/18/14
20140271554 

Reducing proinflammatory response


The present disclosure provides a method for suppressing a proinflammatory response by administering a composition comprising peptides selected from a casein hydrolysate. Such a composition may reduce the levels of proinflammatory cytokines and may be a treatment for inflammatory disease, especially type 1 diabetes.

09/11/14
20140255366 

Novel compositions


The invention relates to a dry compositions for lactic acid bacteria and in particular to a dry composition comprising from 109 to 1013 cfu/g of the composition of lactic acid bacteria cells, wherein the composition is characterized by that it also comprises following amounts of protective agents (all amounts of protective agents below are given relative to 1 g of lactic acid bacteria cells in the composition): from 6 to 9 g of trehalose, from 0.1 to 1 g of inulin and from 0.5 to 3 g of hydrolyzed casein, and by that it does not comprise a salt of alginic acid. The composition has an improved storage stability of the cell of interest.

08/28/14
20140242248 

Continuous cheese production process


Processes and equipment for continuously making a substitute or imitation cheese by feeding a heated first liquid stream including emulsifying salt, water and cheese powder into a cooker which is a twin screw mixer, feeding a heated second liquid stream including oil and casein or a non-dairy protein into the cooker, processing the first liquid stream and the second liquid stream through the cooker to form a cheese composition, and cooling the cheese composition. The cheese composition may be continuously extruded in a desired shape such as sheets or ropes and/or may be continuously cooled and cut into pieces having a reduced size such as a size to approximate shredded cheese..

08/21/14
20140234487 

Dairy based compositions with low lps


The present invention is directed to a method to produce a dairy based food composition with low lps comprising the steps (a) providing a milk with a storage time of less than 264 hours and either (b1) treating the milk with a microfilter of poresize of from 0.01-2 μm such that at least a casein rich fraction and a serum protein rich fraction is obtained, or (b2) treating the milk such that at least 98 wt % of the gram negative bacteria is removed, and heating the milk wherein at least 98wt % of the gram negative bacteria is removed to 60-90° c. The methods of the present invention are very suitable to provide a dairy based food composition wherein less than 5100 eu lps per liter ready to use food composition is present or wherein less than 39 eu lps per gram dry product is present..

08/14/14
20140227422 

Sterilized liquid protein supplement


Disclosed are sterilized liquid protein supplements including extensively hydrolyzed casein for use with human milk and other infant feeding formulas. The sterilized liquid protein supplements have a low ph, thereby inhibiting protein denaturation and reducing microbial growth..

08/07/14
20140219982 

Exogenous opioid peptide-degrading enzyme


The present invention is intended to provide a means for efficiently degrades exogenous opioid peptides. Provided is an exogenous opioid peptide-degrading enzyme preparation which contains one or more components selected from the group consisting of enzyme preparations from penicillium citrinum, aspergillus oryzae, and aspergilius melleus, and exhibits a degradation activity for a wheat gluten-derived opioid peptide and a casein-derived opioid peptide..

07/31/14
20140213762 

Casein hydrolysate


A casein hydrolysate formed by controlled hydrolysis of a casein substrate by an aspergillus-derived (fugal) proteolytic preparation is described. The controlled hydrolysis employs a flavorpro-whey™ formulation and a degree of hydrolysis (% dh) of from 5% dh to 15% dh.

07/31/14
20140213542 

Composition containing s-adenosyl-l-methionine with excellent storage stability


The present invention relates to a composition including s-adenosyl-l-methionine; and at least one kind of additive selected from carboxymethylcellulose, hydroxypropylcellulose, soybean polysaccharide, casein sodium, and zein, in which s-adenosyl-l-methionine is extracted from s-adenosyl-l-methionine-containing cells obtained by culturing a microorganism having an ability to produce same, and the content of the additive in the composition falls within the range of 0.05 to 15 times by mass of s-adenosyl-l-methionine in the composition. The present invention provides a composition containing a high concentration of s-adenosyl-l-methionine, which is useful as a water-soluble physiologically active substance, and being excellent in storage stability and bioabsorbability.



Casein topics: Whey Protein, Emulsifiers, Adrenocorticotropic Hormone, Amino Acid, Membrane Filter, Lactalbumin, Cancer Vaccine, Breast Cancer, Immunization, Polypeptide, Immunogenic, Mammary Gland, Sequencing, Genomic Dna, Casein Protein

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