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Casein patents

      

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new patent Casein kinase 1delta (ck 1delta) inhibitors and their use in the treatment of neurodegenerative diseases such as tauopathies
The invention relates to pharmaceutical compositions comprising casein kinase 1 delta (ck1δ) and to the use of said inhibitors in the treatment of neurodegenerative disorders such as alzheimer's disease.. .
Electrophoretics Limited


Gypsum plaster-based material containing casein and activated carbon
A plaster-based material, in particular a plasterboard intended for the interior fitting of dwellings, contains a mixture of casein and active charcoal. The plaster-based material is used for reducing the amount of volatile organic compounds present in the atmosphere inside dwellings, offices or public buildings..
Saint-gobain Placo


Beta-casein a2 and blood glucose levels
Regulating the level of glucose in the blood of an animal comprising the consumption by the animal of a composition containing beta-casein, or providing the composition to the animal for consumption, where the beta-casein comprises at least 75% by weight beta-casein a2. Uses include managing the symptoms of hyperglycaemia and associated conditions including diabetes.
The A2 Milk Company Limited


Casein peptide for use in the treatment of uterine infections
The present disclosure relates to a casein peptide for use in the treatment of an uterine infection in a female mammalian animal, to methods of treatment of such infections by administering to a female mammalian animal at least one casein peptide, to the use of casein peptide for the preparation of a pharmaceutical composition for treatment of uterine infection and to a kit for said treatment. The casein peptide is preferably a casein hydrolysate, e.g.
Mileutis Ltd.


Multivalent breast cancer vaccine
Compositions and methods for immunization against human breast cancer are disclosed. In one embodiment the multivalent antigenic composition is provided comprising immunogenic polypeptides selected from the group consisting of human α-lactalbumin, αs1 casein, β-casein and κ-casein..
The Cleveland Clinic Foundation


Nutritional composition comprising hydrolyzed protein
Liquid nutritional compositions include specific combinations of protein, carbohydrate, and fat for the nutritional support of individuals with particular needs, such as individual suffering from obesity. The compositions comprise a source of at least one omega-6 fatty acid and a source of at least one omega-3 fatty acid with a ratio of omega-6 to omega-3 of 1:5 to 1:1.
Abbott Laboratories


Liquid nutritional formula for phenylketonuria patients
This is a process to make a shelf-stable, liquid, ready-to-drink, aseptic nutritional formula for the treatment of pku, tyrosinemia or other errors of metabolism. The liquid nutritional formula has caseino-glyco-macropeptide as the primary protein source and complementary essential amino acids to complete the requirement profile.
Cambrooke Therapeutics, Inc.


Methods for determining drug efficacy for the treatment of diffuse large b-cell lymphoma, multiple myeloma, and myeloid cancers
Provided herein, in some embodiments, are methods of using certain cereblon-associated proteins, such as aiolos, ikaros, interferon (ifn), and ifn pathway proteins, casein kinase 1, alpha 1 (csnk1a1), and zfp9, as biomarkers for use in predicting and monitoring clinical sensitivity and therapeutic response to certain compounds in patients having various diseases and disorders, such as cancers (e.g., diffuse large b-cell lymphoma (dlbcl), multiple myeloma (mm), myelodysplasia syndromes (mds) and acute myeloid leukemia (aml)) and ifn-associated disorders. Also provided herein, in certain embodiments, are methods of determining the efficacy of an immunomodulatory compound..
Celgene Corporation


Substituted 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine derivatives as casein kinase 1 d/e inhibitors
And pharmaceutically acceptable salts thereof. The compounds of formula (i) inhibit protein kinase activity thereby making them useful as anticancer agents..

High energy liquid enteral nutritional composition
High energy and high protein liquid nutrition enteral compositions are provided that contain micellar casein and caseinate, an optionally a small amount of whey.. .
N.v. Nutricia


Infant nutrition for improvement in insulin sensitivity later in life

The present invention relates to a nutritional composition for use in treatment, prevention and/or reducing the risk of a metabolic syndrome disorder appearing later in life, wherein the nutritional composition comprises casein.. .
Nestec S.a.

Compositions and methods for treating a pathogenic metabolic condition of the gut microbiota and derived diseases

Calcium caseinate.. .

Concentrate for milky beverages

The present invention relates to a liquid dairy concentrate for mixing with an aqueous medium to form a beverage, the concentrate comprising casein and at least 5 wt % fat, wherein a ratio of fat to casein is from 3:1 to 18:1.. .
Kraft Foods R&d, Inc.

Powdered oil or fat composition and process for producing same

Provided is a powdered oil or fat composition comprising as essential components: an edible oil or fat; an indigestible dextrin; and a casein salt. It is preferable that the powdered oil or fat composition comprises 5 to 84.9% by mass of the edible oil or fat, 5 to 85% by mass of the indigestible dextrin, 0.1 to 10% by mass of the casein salt, and 0.1 to 2% by mass of the edible emulsifier.
The Nisshin Oillio Group, Ltd.

Use of fermented milk product for skin treatment

The use of a fermented milk product comprising non-hydrolysed whey proteins which is substantially free of casein proteins for the purpose of improving skin firmness, by structuring collagen without promoting collagen synthesis, when topically applied to skin is provided.. .
Givaudan S.a.

Novel compositions

The invention relates to a dry compositions for lactic acid bacteria and in particular to a dry composition comprising from 109 to 1013 cfu/g of the composition of lactic acid bacteria cells, wherein the composition is characterized by that it also comprises following amounts of protective agents (all amounts of protective agents below are given relative to 1 g of lactic acid bacteria cells in the composition): from 6 to 9 g of trehalose, from 0.1 to 1 g of inulin and from 0.5 to 3 g of hydrolyzed casein, and by that it does not comprise a salt of alginic acid. The composition has an improved storage stability of the cell of interest.
Chr. Hansen A/s

Improved process for the humanization of animal skim milk

Claimed is the preparation of an infant formula base product, comprising: (a) microfiltration (me) of animal skim milk over a membrane having a porosity of 0.10-0.35 micrometer and operating with a volume concentration factor of 1.5-8, resulting in a retentate (mfr) and a permeate (mfp); (b) ultrafiltration (uf) of the mep originating from step (a) over a membrane having a molecular weight cut-off of at most 25 kda and operating with a volume concentration factor of 1.5-8, resulting in a retentate (ufr) and a permeate fuep); (c) combining the mfr from step (a) and the ufr from step (b), to obtain a defined casein/whey ratio. Alternatively, the product of step (a) is used as a protein source.
N.v. Nutricia

Liquid concentrated human milk fortifier containing hypoallergenic protein and lutein

The present invention is directed to concentrated liquid human milk fortifiers using extensively hydrolyzed casein as a protein source, a stabilizer system comprising octenyl succinic anhydride modified corn starch in combination with a low acyl gellan gum, and the carotenoid lutein.. .
Abbott Laboratories

Composition for transferring gene to cell

Disclosed are a composition for gene transfer, a method for introducing a gene into cell of a non-human animal, a method for introducing a gene into an in vitro cell, and a kit for gene transfer. The composition comprises (a) at least one lipid selected from the group consisting of sorbitan sesquioleate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan trioleate, sorbitan monooleate, l-α-phosphatidylinositol, l-α-dioleoyl phosphatidylethanolamine, octadecylamine, hexadecylamine, dotap, and cardiolipin; (b) at least one protein selected from the group consisting of albumin, casein, gelatin, and sericin; and (c) at least one positively charged substance selected from the group consisting of protamine sulfate, polyarginine, polylysine, polyethyleneimine, and hexadimethrine bromide..
Ishihara Sangyo Kaisha, Ltd.

Method for cleaning tooth surface, composition for cleaning tooth surface, and using the composition

Provided is a method for cleaning tooth surfaces including: applying a composition for cleaning tooth surfaces to tooth surfaces, the composition including: 1 to 20% by weight of a casein phosphopeptide-amorphous calcium phosphate complex and/or a casein phosphopeptide-amorphous calcium fluoride phosphate complex; 0.001 to 3% by weight of xylitol and/or sodium saccharin; 20 to 80% by weight of a wetting agent; 0.1 to 20% by weight of silica whose average particle size is no less than 0.5 μm and no more than 50 μm; and water as a main component of a reminder; and maintaining a state in which a part of the composition for cleaning tooth surfaces remains in a mouth.. .
Gc Corporation

Beta-casein a2 and reducing or preventing symptoms of lactose intolerance

Preventing or reducing the symptoms of lactose intolerance in an animal comprising the consumption by the animal of a composition containing beta-casein, or providing the composition to the animal for consumption, where the beta-casein comprises at least 75% by weight beta-casein a2. The effect is both acute (post-exposure to the composition) and ongoing (future exposure to lactose)..
The A2 Milk Company Limited

Novel substituted pyrazolo-piperazines as casein kinase 1 d/e inhibitors

And pharmaceutically acceptable salts thereof. The compounds of formula (i) inhibit protein kinase activity thereby making them useful as anticancer agents..

Beta-casein a2 and prevention of inflammation of the bowel

The use of a composition for preventing or reducing the risk of inflammation of the bowel in an animal, wherein the composition contains beta-casein and wherein the beta-casein comprises at least 50% by weight beta-casein a2.. .
The A2 Milk Company Limited

Casein coated drug-loaded iron oxide nanoparticles

This disclosure relates to nanoparticle drug delivery systems composed of casein (cn) coated nanoparticles, e.g., iron oxide nanoparticles coated with an inner layer and an out layer comprising the milk protein casein. In certain embodiments, drug molecules are incorporated into an inner polymeric layer coating the nanoparticles, which are subsequently coated with a casein containing outer layer, i.e., a layer-by-layer (lbl) construction.

High protein food

A high protein food may be produced via an extrusion process whereby acid casein is mixed with whey protein, alkali and water. Upon exiting the extruder, the mixture may be cut, dried, and/or tempered, milled and screened before being further processed or packaged.
Erie Foods International, Inc.

Biodegradable fire resistant foam

The instant invention is a fire protectant composition comprising water, a surfactant, a water-soluble polymer, casein, and a calcium salt. The compositions can be applied to materials such as wood in advance of a fire, and after application, the compositions are capable of retaining their fire protectant capacities for days, weeks or even months.
Multi, Inc.

Bone substitute nanocomposites and methods of synthesis using multiphosphorylated peptides

The invention relates to peptides including dede(ssd)ndeg indicated by seq no. 1, rrrdede(ssd)ndeg indicated by seq no.
University Of Pittsburgh - Of The Commonwealth Of Higher Education

Composition and use of a dietary supplement

Composition of a dietary supplement, characterised in that it comprises a mixture of at least a-casein tryptic hydrolysate, siberian or asian ginseng root powder, and lyophilised melon extract.. .
New Matrix, Besloten Vennootschap Met Beperkte Aansprakelijkheid

Casein kinase 1delta (ck 1delta) inhibitors

The invention relates to pharmaceutical compositions having casein kinase 1 delta (ck1δ) inhibitors and to the use of the inhibitors in the treatment of neurodegenerative disorders such as alzheimer's disease.. .
Electrophoretics Limited

Powdered composition for use in an instant milk tea powder

A powdered composition which can be produced by spray-drying, and which can be used as the base of an instant milk tea powder is provided. The powdered composition comprises: 25-35% of di-/tri-saccharides other than lactose; 3-20% of lactose; 2-15% milk protein other than processed soluble caseinate; 35-50% fat; and 3-7% emulsifier.
Conopco, Inc., D/b/a Unilever

Method of producing a composition containing caseinomacropeptide

The present invention pertains to a method of producing caseinomacropeptide (cmp)-containing compositions in high yield and having a very low content of phenylalanine (phe). More specifically, the method involves subjecting a whey derived feed to a combination of ultrafiltration and subsequent cation exchange..
Arla Foods Amba

Protein composition and production process therefor

The present invention provides a protein composition comprising a milk basic protein fraction; and at least one stabilizer selected from the group consisting of soybean polysaccharides, xanthan gum, pectin, gum arabic, gum ghatti, carrageenan, locust bean gum, sodium caseinate, lecithin, and carboxymethylcellulose. The protein composition significantly improves the heat resistance of the milk basic protein fraction.
Megmilk Snow Brand Co., Ltd.

Process and system for preparing dry milk formulae

The invention relates to a process for treating animal skim milk and sweet whey and/or acid whey, comprising: (a) ultrafiltration (uf1) of a first liquid composition comprising animal skim milk with 70-90 wt % casein and 10-30 wt % whey proteins, based on total protein, over a first ultrafiltration membrane having a molecular weight cut-off of 2.5-25 kda using a volume concentration factor of 1.5-6 to obtain a retentate (ufr1) and a permeate (ufp1); (b) ultrafiltration (uf2) of a second liquid composition comprising sweet whey and/or acid whey over a second ultrafiltration membrane having a molecular weight cut-off of 2.5-25 kda using a volume concentration factor of 2-15 to obtain a retentate (ufr2) and a permeate (ufp2); and (c) mixing the uf retentate originating from step (a) with the uf retentate originating from step (b) to obtain a mixture of uf retentates.. .
N.v. Nutricia

Process and system for preparing dry milk formulae

A process and system is disclosed for obtaining a dry milk formula, comprising (a-i) ultrafiltration of an animal skim milk composition comprising 70-90 wt % casein and 10-30 wt % whey proteins, based on total protein, and (a-ii) ultrafiltration of an animal whey composition comprising 0-25 wt % casein and 75-100 wt % whey proteins, based on total protein; or (a-iii) ultrafiltration of a mixture of the compositions of (a-i) and (a-ii), (b) removing polyvalent ions from the uf permeate originating from step (a-i) and/or (a-ii) or (a-iii) to obtain at least one softened uf permeate; (c) combining the at least one softened uf permeate with a uf retentate to obtain a combined product; and (d) drying the combined product to obtain a dry milk formula.. .
N.v. Nutricia

Nutritional compositions including calcium beta-hydroxy-beta-methylbutyrate, casein phosphopeptide, and protein

Nutritional compositions that include calcium ?-hydroxy-?-methylbutyrate and protein, and methods of using and making the nutritional compositions are provided. casein phosphopeptide is utilized to sequester the calcium ?-hydroxy-?-methylbutyrate to reduce the interaction between the divalent calcium ions and protein in the nutritional composition to improve the overall stability, shelf life, and viscosity of the nutritional composition, while also facilitating the absorption of calcium..
Abbott Laboratories

Food product having high milk protein content and process of making same

A food product and process of making the same is provided which results in a high milk protein product having 10% to 25% milk protein content, higher phospholipids compared to unadulterated cow milk, a casein to whey ration of at least 50:50 and is shelf stable for at least six months. In the process whole milk and at least one milk protein source is mixed, heated and contacted with an acid or acidulating substance and co-precipitated to produce a semi-solid precipitate.
Cal Poly Corporation

System and the detection of allergens

Methods and systems for detecting allergens using mass spectrometry are provided herein. In some aspects, a sample can be screened for the presence or quantity of ovalbumin, lysozyme, casein (isoform s1 and s2), lactoglobulin, high and low glutens, wheat, rye, oats, barley, mustard, sesame, and various types of nuts including macadamia, pistachio, brazil, walnuts, peanuts and hazelnuts by detecting one or more peptides specific to the allergen of interest using selected mrm transitions..
Dh Technologies Development Pte. Ltd.

Coated magnetic nanoparticles for imaging enhancement and drug delivery

This disclosure is in the area of diagnostics and nanotechnology. This disclosure provides a method for synthesizing casein coated iron oxide nanoparticles to be used as an mri contrasting agent and targeted drug delivery..
Emory University

Process for the production of cyclosporin-a using the fungus tolypocladium sp. strain nrrl no.: 18950

Provided herein is a process for the production of cyclosporin-a (cyc-a) including the steps of inoculating a nutrient medium with the fungus tolypocladium sp., strain nrrl no. 18950 followed by cultivation under static conditions to obtain a fermented medium with the fungal biomass, and harvesting the biomass and subjecting the harvested biomass to extraction followed by purification to obtain pure cyc-a.
Indian Council Of Medical Research

Method of producing beta-casein compositions and related products

The present invention pertains to a method of producing beta-casein-containing compositions and products obtainable by such methods. More particularly, the invention pertains to a method of producing beta-casein compositions using controlled microfiltration first at a temperature higher than 20 degrees c., followed by cooling of the retentate to 0-15 degrees c.
Arla Foods Amba

Powdery yoghurt material and yoghurt making method

Provided are a yoghurt material for making a homemade yoghurt at home and a yoghurt making method using the yoghurt material. The powdery yoghurt material comprises: a milk powder and a lactic acid bacterium fermented at an ordinary temperature, wherein the powdery yoghurt material is converted into a yoghurt when the material to which water was added is fermented.
Nutrition Act. Co., Ltd.

Substituted benzothiazoles and therapeutic uses thereof for the treatment of human diseases

The invention relates to a family of differently substituted benzothiazoles having inhibitory activity against casein kinase 1 (ck-1) enzyme, as a result of which they are suitable for use in the treatment or prevention of diseases caused by this enzyme, particularly diseases associated with circadian rhythm and inflammatory, autoimmune, psychiatric, neurodegenerative, neurological or ophthalmic diseases, as well as for inducing cell regeneration. .
Consejo Superior De Investigaciones CientÍficas

Method for the preparation of a liquid enteral nutritional composition comprising micellar casein

The invention relates to a method for preparing a shelf-stable liquid enteral composition for providing nutrition, either as a supplement, or as a complete nutrition, comprising a high amount of micellar casein, comprising dissolving a dry blend of micellar casein and digestible carbohydrate.. .
N.v. Nutricia

Method for producing meat substitute products

The invention relates to a method for producing meat substitute products, wherein a mixture of water and a vegetable fat/oil comprising a protein, sodium alginate and methylcellulose is processed by shearing/stirring to produce a stable emulsion, and a colloidal solution of divalent metal cations and micellar casein is added to the emulsion for initiating a fibre formation, wherein the quantity of divalent metal cations is selected such that it leads to the initiation of the fibre formation in combination with the micellar casein.. .
Rovita Gmbh

Novel substituted imidazoles as casein kinase 1 d/e inhibitors

The invention provides compounds of formula (i) and pharmaceutically acceptable salts thereof. The compounds of formula (i) inhibit protein kinase activity thereby making them useful as anticancer agents..
Bristol-myers Squibb Company

Pyrazole substituted imidazopyrazines as casein kinase 1 d/e inhibitors

The invention provides compounds of formula (i) and pharmaceutically acceptable salts thereof. The compounds of formula (i) inhibit protein kinase activity thereby making them useful as anticancer agents..
Bristol-myers Squibb Company

Use of a casein hydrolysate as an antiherpetic agent

The present invention relates to the use of a casein hydrolysate as an antiherpetic agent. This casein hydrolysate has an application in both the treatment and the prevention of the reactivation of a latent infection by a herpesvirus, and is effective both orally and topically.
Ntd Labs, S.l.

Microparticles for encapsulating probiotics, production and uses thereof

The invention relates to microparticles comprising a matrix formed by casein and chitosan, and probiotic bacteria; said matrix protects said probiotic bacteria during (i) processing, (ii) storage and (iii) transit through the gastrointestinal tract, prolonging their lifetime. The present invention also relates to the method for obtaining the microparticles and to the products and compositions incorporating them..
Universidad De Navarra

Cheese compositions and related methods

Described are cheese compositions and methods of making cheese compositions, including methods of formulating cheese compositions, wherein the cheese compositions may include combinations of casein protein, fiber, non-casein protein, non-pregelatinized, modified starch, and a fat component.. .
General Mills, Inc.



Casein topics:
  • Whey Protein
  • Emulsifiers
  • Adrenocorticotropic Hormone
  • Amino Acid
  • Membrane Filter
  • Lactalbumin
  • Cancer Vaccine
  • Breast Cancer
  • Immunization
  • Polypeptide
  • Immunogenic
  • Mammary Gland
  • Sequencing
  • Genomic Dna
  • Casein Protein


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    This listing is a sample listing of patent applications related to Casein for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Casein with additional patents listed. Browse our RSS directory or Search for other possible listings.


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