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Cardiovascular Disease

Cardiovascular Disease-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Measurement of serum lipoproteins
Vap Diagnostics Laboratory Inc.
November 09, 2017 - N°20170322135

Although a more accurate estimate of a person's risk of cardiovascular disease can be made on the basis of the number of lipoprotein particles per unit volume in the person's blood, current methods all rely on measuring the mass of lipoprotein cholesterol per unit volume. It has been discovered that a rapid and accurate lipoprotein particle count can be obtained ...
Amide-substituted pyridinyltriazole derivatives and uses thereof
Bayer Pharma Aktiengesellschaft
November 09, 2017 - N°20170320854

The present invention relates to novel 5-(carboxamide)-1-pyridinyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.
Preparation containing chlorogenic acid crystal form and use thereof
Sichuan Jiuzhang Biological Science And Technology Co., Ltd.
November 09, 2017 - N°20170319530

A preparation containing a chlorogenic acid crystal form. The crystal form is an orthorhombic crystal system, a space group is p212121, cell parameters are as follows: a=7. 7291(2)Å, b=10. 9808(2)Å, c=36. 5334(7)Å, α=β=γ=90. 00°, z=8, and a cell volume is 3100. 65(11)Å3. The content of the chlorogenic acid crystal form in the ...
Cardiovascular Disease Patent Pack
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Cardiovascular Disease Patent Applications
Download 215+ Cardiovascular Disease-related PDFs
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inventor
  • 215+ full patent PDF documents of Cardiovascular Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Fused heterocyclic compounds as selective bmp inhibitors
Sichuan Jiuzhang Biological Science And Technology Co., Ltd.
November 02, 2017 - N°20170313701

The present invention provides small molecule inhibitors of bmp signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with bmp signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation.
Method for the synthesis of hydroxy-triglycerides and uses thereof for the prevention and treament of ...
Sichuan Jiuzhang Biological Science And Technology Co., Ltd.
November 02, 2017 - N°20170313646

The present invention relates to hydroxy-triglycerides, their synthesis, a pharmaceutical and/or nutraceutical composition which comprises at least one of said hydroxy-triglycerides, and a method which comprises the administration to a patient of a therapeutically effective quantity of at least one of said hydroxy-triglycerides or at least one of said pharmaceutical and/or nutraceutical compositions, for the prevention and/or ...
Method for enhanced uptake of viral vectors in the myocardium
Sichuan Jiuzhang Biological Science And Technology Co., Ltd.
November 02, 2017 - N°20170312373

The present invention relates to improved therapies for the treatment of heart disease, particularly the improved delivery of therapeutic agents to heart tissue by direct infusion into the coronary circulation. A preferred embodiment of the invention is a method of treating or preventing a cardiovascular disease by transfecting cardiac cells of a large mammal, the method comprising, identifying a mammal ...
Cardiovascular Disease Patent Pack
Download 215+ patent application PDFs
Cardiovascular Disease Patent Applications
Download 215+ Cardiovascular Disease-related PDFs
For professional research & prior art discovery
inventor
  • 215+ full patent PDF documents of Cardiovascular Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Use of recombinant lymphocyte activation gene-3 as a companion therapeutic for patients at risk for ...
Sichuan Jiuzhang Biological Science And Technology Co., Ltd.
November 02, 2017 - N°20170312338

A method for classifying patients at risk for cardiovascular disease, other chronic inflammatory diseases, cardiovascular and/or non-cardiovascular morbidity and mortality based on a risk assessment for lymphocyte activation gene 3 (lag3) protein deficiency, and for mediating the risk using recombinant lymphocyte activation gene-3 or lag3 mimetic as a companion therapeutic alone or in combination with a statin and/or an ...
Use of nitrite salts in chronic ischemia
Sichuan Jiuzhang Biological Science And Technology Co., Ltd.
November 02, 2017 - N°20170312310

Methods of treating a subject who has chronic tissue ischemia are disclosed. The methods can include administering to the subject a pharmaceutical composition comprising inorganic nitrite or a pharmaceutically acceptable salt thereof, for a time and in an amount sufficient to result in blood vessel growth in the ischemic tissue. The subject can be diagnosed as having a medical condition ...
Measurement of serum lipoproteins
Vap Diagnostics Laboratory Inc.
October 26, 2017 - N°20170307504

Although a more accurate estimate of a person's risk of cardiovascular disease can be made on the basis of the number of lipoprotein particles per unit volume in the person's blood, current methods all rely on measuring the mass of lipoprotein cholesterol per unit volume. It has been discovered that a rapid and accurate lipoprotein particle count can be obtained ...
Anti-endothelial lipase compounds and methods of using the same in the treatment and/or prevention ...
Shifa Biomedical Corporation
October 26, 2017 - N°20170305887

Endothelial lipase (el) inhibitors and methods of using such inhibitors for treating conditions implicating el are provided herein. The present invention meets the needs in the field by providing small molecule inhibitors of el function that can be used therapeutically to raise hdl cholesterol levels in blood, and can be used in the prevention and/or treatment of cholesterol and ...
Compositions and methods for inhibiting bmp
University Of Houston System
October 26, 2017 - N°20170305883

The present invention provides small molecule inhibitors of bmp signaling and compositions and methods for inhibiting bmp signaling. These compounds and compositions may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with bmp signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as ...
Treatment of cardiovascular disease using actrii ligand traps
Washington University
October 26, 2017 - N°20170304397

Provided herein are methods of treating diseases associated with vascular calcification and/or cardiovascular disease in a subject by using the level of a biomarker, in particular, snail homolog 1 (snai1), phosphosmad2, phosphosmad3, urinary protein, dickkopf homolog 1 (dkk1), collagen type 1 alpha 1 (col1a1), activin (e. G., free activin), runt-related transcription factor 2 (runx2), alkaline phosphatase (alp), bone-specific alkaline phosphatase (bsap), c-terminal type 1 ...
Cardiac troponin i detection during pregnancy for cardiovascular disease identification and risk assessment
Washington University
October 19, 2017 - N°20170299612

The present invention provides systems and methods for determining and reporting the cardiac troponin i (ctni) concentration in a sample from a pregnant woman (in the first, second, or third trimester) by determining whether the sample (ctni) concentration is higher than a 99th percentile ctni concentration from a corresponding first, second, or third trimester uncomplicated pregnancy control group, thereby determining ...
Cardiovascular Disease Patent Pack
Download 215+ patent application PDFs
Cardiovascular Disease Patent Applications
Download 215+ Cardiovascular Disease-related PDFs
For professional research & prior art discovery
inventor
  • 215+ full patent PDF documents of Cardiovascular Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin
Washington University
October 19, 2017 - N°20170296506

The present application provides methods for treating cardiovascular conditions. The methods can include administering a transient receptor potential vanilloid 1 (trpv1) receptor agonist to an epidural space. The methods can be used to treat a variety of conditions such as hypertension, prehypertension, mild hypertension, severe hypertension, refractory hypertension, congestive heart failure and myocardial scarring.
Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof
University Of Texas Board Of Regents
October 12, 2017 - N°20170292159

The present invention provides compositions and methods based on genetic polymorphisms that are associated with cardiovascular diseases, particularly coronary heart disease (especially myocardial infarction) or hypertension. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods ...
Methods for treating hyperlipidemia with an angptl8 inhibitor and an angptl3 inhibitor
Regeneron Pharmaceuticals, Inc.
October 12, 2017 - N°20170291937

The present invention provides methods for treating patients suffering from hyperlipidaemia, wherein the patient is non-responsive to, inadequately controlled by, or intolerant to treatment with a standard lipid modifying therapy. The methods of the invention provide for lowering at least one lipid parameter in the patient by administering a therapeutically effective amount of an antibody or antigen-binding fragment thereof that ...
Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with serm
Endorecherche, Inc.
October 12, 2017 - N°20170290847

Novel methods for prevention, reduction or elimination of the incidence of male androgen deficiency symptoms or diseases including male hypogonadism-associated symptoms and diseases associated with low serum testosterone and/or low dhea or low total androgens in susceptible warm-blooded animals including humans involving administration of an amount of a sex steroid precursor, particularly dehydroepiandrosterone (dhea) and a selective estrogen receptor ...
Inhibitors of the renal outer medullary potassium channel
Merck Sharp & Dohme Corp.
October 05, 2017 - N°20170283416

The present invention provides compounds of formula i and the pharmaceutically acceptable salts thereof, which are inhibitors of the romk (kir1. 1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt ...
Chelator-targeting ligand conjugates for cardiovascular imaging
Cell>point, Llc
October 05, 2017 - N°20170281806

Disclosed are methods of imaging a site in a heart of a subject to detect cardiovascular disease that involve stressing a subject, administering to the stressed subject an effective amount of a radionuclide-labeled chelator-glucose analog conjugate, and imaging the heart of the subject by detecting a signal generated by the conjugate in the heart of the subject. Also disclosed are ...
Inhibitors of the renal outer medullary potassium channel
Merck Sharp & Dohme Corp.
September 28, 2017 - N°20170275302

The present invention provides compounds of formula (i) and the pharmaceutically acceptable salts thereof, which are inhibitors of the romk (kir1. 1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt ...
Inhibitors of the renal outer medullary potassium channel
Merck Sharp & Dohme Corp.
September 28, 2017 - N°20170275298

The present invention provides compounds of formula i and the pharmaceutically acceptable salts thereof, which are inhibitors of the romk (kir1. 1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt ...
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