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Cardiovascular Disease

Cardiovascular Disease-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Treatment and prevention of cardiovascular disease and thrombosis
The Cleveland Clinic Foundation
September 14, 2017 - N°20170258740

Provided herein are compositions for the treatment and/or prevention of cardiovascular disease (cvd), and methods of application and use thereof. In particular, the present invention provides treatment and/or prevention of cardiovascular disease with compounds that inhibit the production of tma in the gut, such as 3,3-dimethyl-1-butanol (dmb) or other compounds represented by formula i or as shown ...
Methods for treating patients with hyperlipidemia by administering a pcsk9 inhibitor in combination with an ...
Regeneron Pharmaceuticals, Inc.
September 07, 2017 - N°20170253666

The present invention provides methods for treating patients suffering from hypercholesterolemia, wherein the patient is non-responsive to, inadequately controlled by, or intolerant to treatment with a standard lipid modifying therapy. The methods of the invention provide for lowering at least one lipid parameter in the patient by administering a therapeutically effective amount of an antibody or antigen-binding fragment thereof that ...
Extended antegrade epicardial coronary infusion of adeno-associated viral vectors for gene therapy
Celladon Corporation
September 07, 2017 - N°20170252462

The present invention relates to therapies for the treatment of cardiovascular diseases, particularly the delivery of therapeutic agents to heart tissue by direct infusion into the coronary circulation. A preferred embodiment of the invention is a method of treating or preventing a cardiovascular disease by transfecting cardiac cells of a large mammal, the method comprising, identifying an mammal in need ...
Cardiovascular Disease Patent Pack
Download 215+ patent application PDFs
Cardiovascular Disease Patent Applications
Download 215+ Cardiovascular Disease-related PDFs
For professional research & prior art discovery
inventor
  • 215+ full patent PDF documents of Cardiovascular Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Diagnostic method for disorders using copeptin
B.r.a.h.m.s Gmbh
August 24, 2017 - N°20170242037

Disclosed herein is the use of copeptin as a diagnostic marker for the determination of the release of vasopressin, especially in connection with disorders associated with non-physiological alterations of vasopressin release from the neurohypophysis, especially for detection and early detection, diagnosing and monitoring of the course of cardiovascular diseases, renal and pulmonary diseases as well as shock, including septic shock, ...
Soluble epoxide hydrolase inhibitors and uses thereof
X-chem, Inc.
August 24, 2017 - N°20170240526

The present invention features compounds having soluble epoxide hydrolase inhibitory activity. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions, such as cardiovascular diseases, respiratory diseases, inflammation, and diabetes.
Toxic aldehyde related diseases and treatment
Aldeyra Therapeutics, Inc.
August 24, 2017 - N°20170239196

The present invention provides for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, ...
Cardiovascular Disease Patent Pack
Download 215+ patent application PDFs
Cardiovascular Disease Patent Applications
Download 215+ Cardiovascular Disease-related PDFs
For professional research & prior art discovery
inventor
  • 215+ full patent PDF documents of Cardiovascular Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Genetic markers for predicting responsiveness to therapy with hdl-raising or hdl mimicking agent
Hoffmann-la Roche Inc.
August 17, 2017 - N°20170233812

Genotyping methods and compositions for selecting patients with cardiovascular disease who will benefit from treatment with hdl-raising or hdl mimicking agent, in particular with a cetp inhibitor/modulator
Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations
Ionis Pharmaceuticals, Inc.
August 17, 2017 - N°20170233732

Provided herein are methods, compounds, and compositions for reducing expression of apociii mrna and protein in a patient with fredrickson type i dyslipidemia, fcs, lpld. Also provided herein are methods, compounds, and compositions for treating, preventing, delaying, or ameliorating fredrickson type i dyslipidemia, fcs, lpld, in a patient. Further provided herein are methods, compounds, and compositions for increasing hdl levels ...
Cyclic polypeptides for the treatment of heart failure
Ionis Pharmaceuticals, Inc.
August 17, 2017 - N°20170233443

Or an amide, an ester or a salt thereof, or a bioconjugate thereof, wherein x1, x3, x4, x7, x8, x9, x10, x11, x12 and x13 are defined herein. The polypeptides are agonist of the apj receptor. The invention also relates to a method for manufacturing the polypeptides of the invention or bioconjugates thereof, and their therapeutic uses such as treatment ...
Organic compounds
Intra-cellular Therapies, Inc.
August 17, 2017 - N°20170233399

The invention relates to novel inhibitors of phosphodiesterase 1 (pde1), useful for the treatment of diseases or disorders characterized by disruption of or damage to certain cgmp/pkg mediated pathways (e. G., in cardiac tissue). The invention further relates to pharmaceutical composition comprising the same and methods of treatment of cardiovascular disease and related disorders, e. G., congestive heart disease, atherosclerosis, ...
Aza-heteroaryl compounds as pi3k-gamma inhibitors
Intra-cellular Therapies, Inc.
August 17, 2017 - N°20170232016

And pharmaceutically acceptable salts thereof, wherein x, y, z, a, w, r4, r5, and r6 are defined herein, that inhibit the activity of phosphoinositide 3-kinases-gamma (pi3kγ) and are useful in the treatment of diseases related to the activity of pi3kγ including, for example, autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.
Preparation and uses of obeticholic acid
Intra-cellular Therapies, Inc.
August 10, 2017 - N°20170226149

Or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. Obeticholic acid is useful for the treatment or prevention of a fxr mediated disease or condition, cardiovascular disease or cholestatic liver disease, and for reducing hdl cholesterol, for lowering triglycerides in a mammal, or for inhibition of fibrosis. The present invention also relates to processes for the synthesis of ...
Organic compounds
Intra-cellular Therapies, Inc.
August 10, 2017 - N°20170226117

The invention relates to novel inhibitors of phosphodiesterase 1 (pde1), useful for the treatment of diseases or disorders characterized by disruption of or damage to certain cgmp/pkg mediated pathways (e. G., in cardiac tissue). The invention further relates to pharmaceutical composition comprising the same and methods of treatment of cardiovascular disease and related disorders, e. G., congestive heart disease, atherosclerosis, ...
Cardiovascular Disease Patent Pack
Download 215+ patent application PDFs
Cardiovascular Disease Patent Applications
Download 215+ Cardiovascular Disease-related PDFs
For professional research & prior art discovery
inventor
  • 215+ full patent PDF documents of Cardiovascular Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Piperazine derivatives as liver x receptor modulators
Vitae Pharmaceuticals, Inc.
August 10, 2017 - N°20170226067

Provided are novel compounds of formula (i): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are liver x receptor modulators, and which are useful in the treatment of diseases and disorders associated with the liver x receptor. Also provided are the compounds of formula (i) and pharmaceutical compositions thereof for treating atherosclerosis, cardiovascular disease, alzheimer's disease, dermatitis, dyslipidemia, cancer ...
Methods for reducing ldl-cholesterol
Rinat Neuroscience Corp.
August 10, 2017 - N°20170224816

The present invention relates to methods for the treatment of reducing ldl-cholesterol levels in a subject infected with hepatitis c virus (hcv) or at high risk of contracting hcv comprising administration to the subject in need thereof a therapeutically effective amount of an antagonist antibody which specifically binds to a human pcsk9 protein. The subject treatment can be used in ...
Nutritional support method for health issues
Cortcontrol
August 10, 2017 - N°20170224746

A method of improving the outcome or recovery for depression, diabetes, cardiovascular disease, alzheimers progression, or breast cancer. This method consists of administering a food which includes transfer factor, lactic acid generating bacteria, and/or glucans in appropriate combinations and dosage levels. The food reduces cortisol levels, enhances the immune system, and balances hormones and cytokines. Dosage amounts are dependent ...
Phospholipid-containing marine extracts for treatment of cardiovascular diseases
Neptune Technologies & Bioressources, Inc.
August 10, 2017 - N°20170224742

The present invention relates to a method of treatment and/or prevention of cardiovascular disease, rheumatoid arthritis, skin cancer, premenstrual syndrome, diabetes and transdermal transport enhancement. The method comprises the administration of a therapeutically effective amount of krill and/or marine oil to a patient. The present invention also relates to a composition for the treatment and/or prevention of ...
Methods for treating thrombosis using chimeric and humanized anti-histone antibodies
Immunomedics, Inc.
August 03, 2017 - N°20170218059

The present invention concerns chimeric or humanized antibodies or antigen-binding fragments thereof that comprise specific cdr sequences, disclosed herein. Preferably, the antibodies or fragments comprise specific heavy and light chain variable region sequences disclosed herein. More preferably, the antibodies or fragments also comprise specific constant region sequences, such as those associated with the ng1m1,2 or km3 allotypes. The antibodies ...
Novel 3-amino-pyrrolo[3,4-c]pyrazole-5(1h, 4h,6h) carbaldehyde derivatives
Immunomedics, Inc.
August 03, 2017 - N°20170217991

Wherein a, b, r1, r2, r3, r4, r5, r6, r7, r8, r9 and r10 are as defined above. The invention further relates to pharmaceutical compositions comprising the compounds and pharmaceutically acceptable salts and to methods of treating diabetes mellitus and its complications, cancer, ischemia, inflammation, central nervous system disorders, cardiovascular disease, alzheimer's disease and dermatological disase pression, virus diseases, inflammatory ...
Organic compounds
Intra-cellular Therapies, Inc.
August 03, 2017 - N°20170217975

The invention relates to novel inhibitors of phosphodiesterase 1 (pde1), useful for the treatment of diseases or disorders characterized by disruption of or damage to certain cgmp/pkg mediated pathways (e. G., in cardiac tissue). The invention further relates to pharmaceutical composition comprising the same and methods of treatment of cardiovascular disease and related disorders, e. G., congestive heart disease, atherosclerosis, ...
4-aryl-n-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group
Bayer Intellectual Property Gmbh
August 03, 2017 - N°20170217949

The present invention relates to 4-aryl-n-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group of general formula (i) or (ia) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate ...
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