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Cardiac Arrhythmia patents



      
           
This page is updated frequently with new Cardiac Arrhythmia-related patent applications. Subscribe to the Cardiac Arrhythmia RSS feed to automatically get the update: related Cardiac RSS feeds. RSS updates for this page: Cardiac Arrhythmia RSS RSS


Methods and compositions for correlating genetic markers with sudden cardiac death risk

Duke University

Methods and compositions for correlating genetic markers with sudden cardiac death risk

Separating clinically relevant sources of electrical activity in ecg signals

Ben-gurion University Of Negev Research & Development Authority

Separating clinically relevant sources of electrical activity in ecg signals


Date/App# patent app List of recent Cardiac Arrhythmia-related patents
08/13/15
20150223760 
 Screening procedure for identifying risk of arrhythmia patent thumbnailScreening procedure for identifying risk of arrhythmia
A screening procedure and apparatus enables those at risk of cardiac arrhythmia to be identified. The procedure utilises a blood flow detector (12) in conjunction with a signal analysis unit (18) to monitor a sequence of multiple heart pulses, hence to deduce the values of a sequence of multiple heart pulse intervals, and to analyse the sequence of multiple heart pulse intervals to deduce a risk parameter whose value enables those at risk of cardiac arrhythmia to be identified.
To Health Limited


07/30/15
20150211066 
 Methods and compositions for correlating genetic markers with sudden cardiac death risk patent thumbnailMethods and compositions for correlating genetic markers with sudden cardiac death risk
The present invention provides a method of identifying a subject as having an increased risk of sudden cardiac death or cardiac arrhythmia by detecting in the subject the presence of various polymorphisms associated with an increased risk of sudden cardiac death or cardiac arrhythmia.. .
Duke University


07/30/15
20150208939 
 Separating clinically relevant sources of electrical activity in ecg signals patent thumbnailSeparating clinically relevant sources of electrical activity in ecg signals
This invention provides a fully automatic method and a system for detecting and classifying cardiac arrhythmias from a surface ecg record. The method defines four relevant parameters whose values are extracted from said ecg record.
Ben-gurion University Of The Negev Research & Development Authority


07/23/15
20150202451 
 Multisite heart pacing with adjustable number of pacing sites for terminating high frequency cardiac arrhythmias patent thumbnailMultisite heart pacing with adjustable number of pacing sites for terminating high frequency cardiac arrhythmias
High frequency cardiac arrhythmias and fibrillations are terminated by electric field pacing pulses having an order of magnitude less energy than a conventional cardioversion or defibrillation energy. The frequency and number of the pulses are selected based on a frequency analysis of a present high frequency cardiac arrhythmia or fibrillation.
Max-planck-gesellschaft Zur Foerderung Der Wissenschaften E.v


07/23/15
20150201991 
 Ablation of myocardial tissues with nanosecond pulsed electric fields patent thumbnailAblation of myocardial tissues with nanosecond pulsed electric fields
An apparatus and methods for performing ablation of myocardial tissues are disclosed. The apparatus includes a plurality of ablation electrode configurations to which nanosecond pulsed electric fields are applied.
Old Dominion University Research Foundation


07/16/15
20150197475 
 Tri-salt form of metformin patent thumbnailTri-salt form of metformin
Provided herein are tri-salt compounds comprising a compound having two acidic functional groups and one basic functional groups (e.g., aspartate or glutamate), metformin, and polyunsaturated fatty acids, such as eicosapentaenoate or docosahexaenoate. The salts can be used in the treatment of diabetes, diabetes with concomitant dyslipidemia (e.g., high triglycerides) and diabetes exacerbated cardiovascular complications, such as cardiac arrhythmia, cardiac ischemia, myocardial infarction, cardiomyopathy, and stroke.
Thetis Pharmaceuticals Llc


07/16/15
20150196758 
 Systems and methods for detecting cardiac arrhythmias patent thumbnailSystems and methods for detecting cardiac arrhythmias
Systems and methods for coordinating detection and/or treatment of abnormal heart activity using multiple implanted devices within a patient. In one example, cardiac activity may be sensed by two or more medical device, including a leadless cardiac pacemaker.
Cardiac Pacemakers, Inc.


07/16/15
20150196757 
 Communication of therapy activity of a first implantable medical device to another implantable medical device patent thumbnailCommunication of therapy activity of a first implantable medical device to another implantable medical device
Cardiac activity of the heart can be sensed using, for example, one or more leadless cardiac pacemakers (lcps) that are implanted in a close proximity to the heart. Sensing cardiac activity by the one or more leadless cardiac pacemakers (lcps) can help the system in determining an occurrence of cardiac arrhythmia.
Cardiac Packemakers, Inc.


07/16/15
20150196756 
 Systems and methods for treating cardiac arrhythmias patent thumbnailSystems and methods for treating cardiac arrhythmias
Systems and methods for coordinating treatment of abnormal heart activity using multiple implanted devices within a patient. In one example, abnormal heart activity may be sensed by a medical device system.
Cardiac Pacemakers, Inc.


07/16/15
20150196605 
 Compositions and methods for preventing cardiac arrhythmia patent thumbnailCompositions and methods for preventing cardiac arrhythmia
Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject.. .
Cormatrix Cardiovascular, Inc.


07/02/15
20150183842 

Cardiac arrhythmia treatment methods


Disclosed are methods of preventing or treating cardiac arrhythmia. In one embodiment, the methods include administering to an amount of at least one polynucleotide that modulates an electrical property of the heart.
The Johns Hopkins University


07/02/15
20150182171 

Sensing vector selection in a cardiac stimulus device with postural assessment


Methods, implantable medical devices and systems configured to perform analysis of captured signals from implanted electrodes to identify cardiac arrhythmias. In an illustrative embodiment, signals captured from two or more sensing vectors are analyzed, where the signals are captured with a patient in at least first and second body positions.
Cameron Health, Inc.


06/25/15
20150173828 

Small loop ablation catheter


A catheter system for creating lesions for the treatment of cardiac arrhythmias is disclosed that includes a catheter having a distal ablation segment that has an electrode array comprising a plurality of spaced ablation and recording electrode devices arranged in a tight loop configuration that is used to create a series of overlapping loop-shaped ablation footprints to produce a continuous lesion resembling a chain-link configuration.. .

06/18/15
20150164960 

Compositions and methods for preventing cardiac arrhythmia


Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject.. .
Cormatrix Cardiovascular, Inc.


06/18/15
20150164959 

Compositions and methods for preventing cardiac arrhythmia


Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject.. .
Cormatrix Cardiovascular, Inc.


06/18/15
20150164871 

Pharmaceutical compositions for combination therapy


This invention relates to the use of pharmaceutical compositions comprising a therapeutically effective amount of a sodium channel inhibitor, in a combination with a small-conductance calcium-activated potassium (sk) channel inhibitor, for the treatment of cardiac arrhythmias.. .
Acesion Pharma


06/11/15
20150157764 

Compositions and methods for preventing cardiac arrhythmia


Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject.. .
Cormatrix Cardiovascular, Inc.


06/04/15
20150150914 

Compositions and methods for preventing cardiac arrhythmia


Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject.. .
Cormatrix Cardiovascular, Inc.


06/04/15
20150150913 

Compositions and methods for preventing cardiac arrhythmia


Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject.. .
Cormatrix Cardiovascular, Inc.


05/28/15
20150148854 

Medical monitoring and treatment device with external pacing


A non-invasive bodily-attached ambulatory medical monitoring and treatment device with pacing is provided. The noninvasive ambulatory pacing device includes a battery, at least one therapy electrode coupled to the battery, a memory storing information indicative of a patient's cardiac activity, and at least one processor coupled to the memory and the at least one therapy electrode.
Zoll Medical Corporation


05/21/15
20150142070 

Systems and methods for leadless cardiac resynchrinization therapy


Techniques and systems for monitoring cardiac arrhythmias and delivering electrical stimulation therapy using a subcutaneous device (e.g. Subcutaneous implantable (sd)) is described.
Medtronic, Inc.


05/21/15
20150142069 

Systems and methods for leadless cardiac resynchronization therapy


Techniques and systems for monitoring cardiac arrhythmias and delivering electrical stimulation therapy using a subcutaneous device (e.g. Subcutaneous implantable (sd)) and a leadless pacing device (lpd) are described.
Medtronic, Inc.


05/21/15
20150139966 

Methods of using hcn genes to treat cardiac arrhythmias


The subject invention is directed to methods of treating cardiac pacing dysfunction by administering hcn genes, alone or in combination with other genes.. .
Medtronic, Inc.


05/14/15
20150134030 

Cardiac defibrillation with vagus nerve stimulation


A method and system for treating cardiac arrhythmias which includes inserting one or more electrodes into a patient's neck, and connecting the electrodes to the vagus nerve in the patient's neck. A cardiac monitoring device detects a cardiac arrhythmia.

05/14/15
20150133909 

Energy delivery systems and uses thereof


The present invention relates to comprehensive systems, devices and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, systems, devices, and methods are provided for treating a tissue region (e.g., a tumor) through application of energy..

05/14/15
20150133527 

Regulation of cardiac sodium channels by sirt1 and sirt1 activators


Methods are provided herein for treating cardiac arrhythmias, such as for treating an arrhythmia syndrome, for example brugada syndrome, in a subject. In some embodiments, the methods include selecting a subject with brugada syndrome and administering to the subject an effective amount of an agent that increases the expression or activity of sirt1 in the subject.

05/07/15
20150126884 

System for heart performance characterization and abnormality detection


A system improves analysis, diagnosis and characterization of cardiac function signals (including surface ecg signals and intra-cardiac electrograms) based on cardiac electrophysiological activity momentum computation, characterization and mapping. The system calculates an electrophysiological signal momentum of different portions of cardiac signals including a timing, location and severity of cardiac pathology and improves reliability of diagnosis, detection, mapping to an identified medical condition, and characterization.
Siemens Medical Solutions Usa, Inc.


04/30/15
20150119670 

Devices, systems, and methods for treating cardiac arrhythmias


Medical devices are described for performing mapping, ablating, pacing, and/or defibrillating procedures on one or more layers of the cardiac wall via an epicardial or extra-pericardial approach in a minimally invasive (e.g., orthoscopic) surgical procedure. One of the medical devices described includes a main support member and one or more secondary support members extending outwardly from the main support member having electrodes configured to receive electrical impulses.
The Charlotte-mecklenburg Hospital Authority D/b/a Carolinas Healthcare System


03/19/15
20150080977 

Implantable medical device telemetry in disruptive energy field


An implantable medical device may include a telemetry module, a sensing module, a therapy delivery module, and a processor. The processor may be configured to detect a patient event based on data generated by the sensing module, operate the imd in a first mode in which the telemetry module is disabled and the therapy delivery module is at least partially disabled when the patient event is not detected, and operate the imd in a second mode in which the telemetry module is enabled and the therapy delivery module is at least partially disabled when the patient event is detected.
Medtronic, Inc.


03/12/15
20150073246 

Method for mapping ventricular/atrial premature beats during sinus rhythm


While detecting a cardiac arrhythmia, a mapping electrode of a probe is used to associate a local activation time with a first location in a region of interest in the heart. While detecting an absence of the cardiac arrhythmia, the local activation time is associated with a second location in the heart.
Biosense Webster (israel) Ltd.


02/05/15
20150037431 

Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities


Methods and kits for treating a cardiac arrhythmia using a platelet rich plasma (prp) composition are provided. Any type of arrhythmia may be treated using the prp composition.
Bioparadox, Llc


01/15/15
20150018693 

Method and monitoring a subject for atrial fibrillation


What is disclosed is a method for monitoring a subject for cardiac arrhythmia such as atrial fibrillation using an apparatus that can be comfortably worn by the subject around an area of exposed skin where a photoplethysmographic (ppg) signal can be registered. In one embodiment, the apparatus is a reflective or transmissive wrist-worn device with emitter/detector pairs fixed to an inner side of a band with at least one illuminator emitting source light at a specified wavelength band.
Xerox Corporation


01/01/15
20150005652 

Database and algorithm for evaluating efficacy of an electrophysiology procedure


The present invention provides an improved, internet-based system that seamlessly collects cardiovascular data from a patient before, during, and after a procedure for ep or an id. During an ep procedure, the system collects information describing the patient's response to pes and the ablation process, ecg waveforms and their various features, hr and other vital signs, hr variability, cardiac arrhythmias, patient demographics, and patient outcomes.
Perminova Inc.


01/01/15
20150005650 

Internet-based system for evaluating t waves within ecg waveforms to determine the presence of cardiac abnormalities


The present invention provides an improved, internet-based system that seamlessly collects cardiovascular data from a patient before, during, and after a procedure for ep or an id. During an ep procedure, the system collects information describing the patient's response to pes and the ablation process, ecg waveforms and their various features, hr and other vital signs, hr variability, cardiac arrhythmias, patient demographics, and patient outcomes.
Perminova Inc.


12/25/14
20140377217 

Compositions for preventing cardiac arrhythmia


Disclosed herein are compositions and methods for treating or preventing a cardiac arrhythmia in a subject.. .

12/18/14
20140371804 

Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries


A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a relatively low voltage electric field in such a way as to effectively unpin the anatomical reentry. Preferably, the relatively low voltage electric field is defined by at least one unpinning shock(s) that are lower than an expected lower limit of vulnerability as established, for example, by a defibrillation threshold test.
Washington University


12/11/14
20140364757 

Cardio mapping cardio mapping


A method and system for determining the mechanism of cardiac arrhythmia in a patient is disclosed. The method basically entails measuring the impedance of cardiac tissue in a portion of the patient's heart using a catheter during an episode of supraventricular tachycardia to produce an iso-impedance map of that cardiac tissue on a video display and analyzing the pattern of the iso-impedance map to differentiate focal arrhythmia caused by a circumscribed region of focal firing and reentrant arrhythmia caused by a macroreentrant circuit.

12/11/14
20140363841 

Induced pluripotent stem cell (ipsc)-derived cardiomyocyte-like cells and uses thereof


The present invention relates to a method for screening an agent as a drug candidate using induced pluripotent stem cell-derived cardiomyocyte-like cells (ipsc-cms). The method is useful for screening cardiovascular agents and/or agents affecting cardiac function.

11/27/14
20140350631 

Sensing vector selection in a cardiac stimulus device with postural assessment


Methods, implantable medical devices and systems configured to perform analysis of captured signals from implanted electrodes to identify cardiac arrhythmias. In an illustrative embodiment, signals captured from two or more sensing vectors are analyzed, where the signals are captured with a patient in at least first and second body positions.

11/27/14
20140350422 

Systems for detecting cardiac arrhythmias


A system for calculating a variability value that is indicative of af by obtaining a signal sequence of a plurality of rr intervals by monitoring electrical activity of a patient's heart. Each rr interval is converted into an instantaneous heart rate value and sorted into ascending order.

11/20/14
20140343444 

Rapid visual cuing cardiac ekg rhythms


The present invention is a visual cuing device which allows users to rapidly and easily identify ecg/ekg cardiac arrhythmias and twelve lead ecg/ekg arrhythmias. A visual cuing device contains a plurality of panels with a plurality of graphically displayed ecg/ekg abnormalities alternated with visually high-contrast, solid colored text sections.

11/13/14
20140336718 

Adaptive medium voltage therapy for cardiac arrhythmias


Aspects of the invention are directed to advanced monitoring and control of medium voltage therapy (mvt) in implantable and external devices. Apparatus and methods are disclosed that facilitate dynamic adjustment of mvt parameter values in response to new and changing circumstances such as the patient's condition before, during, and after administration of mvt.

11/06/14
20140330091 

Heart failure decompensation prediction based on cardiac rhythm


Systems and methods of detecting an impending cardiac decompensation of a patient measure an electrocardiogram signal of the patient. An incidence of cardiac arrhythmias is determined from the electrocardiogram signal.

11/06/14
20140329311 

Induction of human embryonic stem cell derived cardiac pacemaker or chamber-type cardiomyocytes by manipulation of neuregulin signaling


The present invention is directed to methods of producing cardiomyocytes having a nodal/pacemaker phenotype and cardiomyocytes having an atrial/ventricular phenotype. Isolated populations of nodal/pacemaker and atrial/ventricular cardiomyocytes are also disclosed.

10/23/14
20140316385 

Methods of treating a cardiac arrhythmia by thoracoscopic production of a cox maze iii lesion set


Methods of treating a subject for a cardiac arrhythmia are provided. Aspects of the methods include thoracoscopically producing a cardiac cox maze iii set of lesions in cardiac tissue of the subject in a manner sufficient to treat the subject for the cardiac arrhythmia..

10/02/14
20140296335 

Short acting phenylalkylamine calcium channel blockers and uses thereof


The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods..

09/18/14
20140277305 

Devices, systems, and methods for managing patient temperature and correcting cardiac arrhythmia


Methods, devices, and systems for temperature management and ventricular defibrillation are disclosed. Methods, devices, and systems for positioning an electrode in the esophagus of a subject and managing the core body temperature of the subject are disclosed.

09/04/14
20140249221 

Tri-salt form of metformin


Provided herein are tri-salt compounds comprising a compound having two acidic functional groups and one basic functional groups (e.g., aspartate or glutamate), metformin, and polyunsaturated fatty acids, such as eicosapentaenoate or docosahexaenoate. The salts can be used in the treatment of diabetes, diabetes with concomitant dyslipidemia (e.g., high triglycerides) and diabetes exacerbated cardiovascular complications, such as cardiac arrhythmia, cardiac ischemia, myocardial infarction, cardiomyopathy, and stroke.

08/28/14
20140243641 

Methods and system for real-time cardiac mapping


A method and system of electroanatomical mapping comprises bringing a patient's image such as a fluoroscopic image and intracardiac signals into a computer based mapping system. Electroanatomical mapping or superimposing of cardiac electrical activity on fluoroscopic image is provided by placing visual indicators on electrode pairs of various catheters including standard catheters and ablation catheter.

08/14/14
20140227693 

Genetic markers for risk management of atrial fibrillation, atrial flutter, and stroke


The invention relates to procedure and methods of determining a susceptibility to cardiac arrhythmia, including atrial fibrillation, atrial flutter and stroke, by assessing the presence or absence of alleles at polymorphic markers found to be associated with atrial fibrillation, atrial flutter and stroke. The invention further relates to kits encompassing reagents for assessing such markers, and diagnostic methods, uses and procedures for utilizing such susceptibility markers..

08/07/14
20140222097 

Apparatus and identifying atrial arrhythmia by far-field sensing


In a subcutaneous implantable cardioverter/defibrillator, cardiac arrhythmias are detected to determine necessary therapeutic action. Cardiac signal information is sensed from far field electrodes implanted in a patient.

08/07/14
20140221993 

Cardiac ablation devices and methods


Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often used to ablate epicardial tissue in the vicinity of at least one pulmonary vein, various embodiments may be used to ablate other cardiac tissues in other locations on a heart.

08/07/14
20140221845 

Determining cardiac arrhythmia from a video of a subject being monitored for cardiac function


What is disclosed is a system and method for processing a time-series signal generated by video images captured of a subject of interest in a non-contact, remote sensing environment such that the existence of a cardiac arrhythmia can be determined for that subject. In one embodiment, a time-series signal generated is received.

07/31/14
20140214104 

Systems and methods for leadless pacing and shock therapy


Techniques and systems for monitoring cardiac arrhythmias and delivering electrical stimulation therapy using a subcutaneous implantable cardioverter defibrillator (sicd) and a leadless pacing device (lpd) are described. For example, the sicd may detect a tachyarrhythmia within a first electrical signal from a heart and determine, based on the tachyarrhythmia, to deliver anti-tachyarrhythmia shock therapy to the patient to treat the detected arrhythmia.

07/17/14
20140200183 

Treatment of cardiac arrhythmias


Compositions of the invention, including compounds that bind to a receptor for a glucagon-like peptide-1, an incretin, a glucagon-like peptide-1 (glp-1), an exendin, or an agonist, an analog (preferably an agonist analog), a derivative, or a variant of any of aforementioned compounds, are used in the prevention and treatment of arrhythmias associated with cardiac ischemia, cardiac ischemia-perfusion and/or congestive heart failure. The invention relates to both the method and compositions for such treatment..

07/03/14
20140187895 

Delivery system for delivering a medical device to a location within a patient's body


Devices, systems and methods are provided for deployment of one or more functional devices, such as therapeutic and/or diagnostic medical devices and/or positioning devices, at various locations relative to a defined operative path. The devices, systems, and methods can include a guide system and a positioning element.

06/12/14
20140163343 

Apparatus, system, and monitoring physiological signs


An apparatus, system, and method monitors the motion, breathing, heart rate and sleep state of subjects, e.g., humans, in a convenient, non-invasive/non-contact, and low-cost fashion. More particularly, the motion, breathing, and heart rate signals are obtained through processing applied to a raw signal obtained in a non-contact fashion, typically using a radio-frequency sensor.

06/12/14
20140162970 

Treating cardiac arrhythmias, heart failure, peripheral artery disease and stroke with cyclopentyl-triazolo-pyrimidine or derivative thereof


The present invention relates to new methods for treating and/or preventing cardiac arrhythmias, heart failure, stroke and/or peripheral artery disease by administering a composition comprising triazolopyrimidine, or derivative or metabolite thereof. In particular, the present invention relates to methods for treating cardiac arrhythmias, heart failure, stroke and/or peripheral artery disease by administering cyclopentyl-triazolopyrimidine..

06/05/14
20140155885 

Cardiac ablation devices and methods


Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. The devices and methods are used to ablate epicardial tissue in the vicinity of the pulmonary veins, and other locations on a heart.

05/01/14
20140122048 

System and personalized cardiac arrhythmia risk assessment by simulating arrhythmia inducibility


A method of determining a likelihood of an occurrence of a cardiac arrhythmia in a patient includes receiving three-dimensional imaging data of said patient's heart, constructing a whole-heart model for simulating at least one of electrophysiological activity or electromechanical activity of the patient's heart using the three-dimensional imaging data, simulating a response of the patient's heart to each of a plurality of stimulations to a corresponding plurality of different locations within the patient's heart using the whole-heart model, classifying each simulation outcome for each stimulation as one of a normal heart rhythm or a cardiac arrhythmia, calculating a likelihood index based on results of the classifying, and determining the likelihood of the occurrence of the cardiac arrhythmia in the patient based on the likelihood index. Software and data processing systems that implement the above methods are also provided..

04/24/14
20140114167 

Patient-readable portable cardiac monitor


Systems and devices to gather data from a subject's heart, analyze said data to determine whether the subject is experiencing cardiac arrhythmia, and display results of said determining. Use, and display of cardiac condition information, are preferably simple and unambiguous to untrained users..

04/24/14
20140113008 

Assessment of iron deposition post myocardial infarction as a marker of myocardial hemorrhage


The invention is directed to methods for diagnosing reperfusion/non-reperfusion hemorrhage and predicting cardiac arrhythmias and sudden cardiac death in subjects comprising using imaging techniques to detect regional iron oxide deposition. The invention also provides treatment methods for subject at increased risk of sudden cardiac death..



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Cardiac Arrhythmia topics: Arrhythmia, Cardiac Arrhythmia, Arrhythmias, Cardiac Arrhythmias, Fibrillation, Medical Device, Implantable Medical Device, Epinephrine, Ventricular, Tachycardia, Atrial Fibrillation, Atrial Fib, Electrical Signal, Sleep Apnea, Rheumatoid Arthritis

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