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Cancer patents

      

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 Light-trapping cancer cell stage testing method patent thumbnailLight-trapping cancer cell stage testing method
A light-trapping cancer cell stage testing method includes: measuring a first average escape velocity or range of first cancer cells and a second average escape velocity or range of second cancer cells whose stage is known and differ from that of the first cancer cells and whose types are known; utilizing the first average escape velocity and the second average escape velocity to calculate a reference ratio to build a database; selecting stage-unknown cancer cells and measuring an escape velocity of the stage-unknown cancer cells (type-known); utilizing the escape velocity of the stage-unknown cancer cells and an escape velocity of reference-stage cancer cells to calculate a ratio; and determining a stage of the stage-unknown cancer cells with a result comparing the ratio of the escape velocities for the stage-unknown cancer cells with the reference ratios stored in the database.. .
National Kaohsiung University Of Applied Sciences


 Treating bax(delta)2-positive cancer with chemotherapies targeting caspase 8 patent thumbnailTreating bax(delta)2-positive cancer with chemotherapies targeting caspase 8
Discovery of a new bax isoform, baxΔ2, in cancer cell lines and primary tumors is described. The baxΔ2 isoform resulted from combination of bax microsatellite mutation and alternative splicing bax exon 2.
Mumetel, Llc


 Foxc1 antibodies and methods of their use patent thumbnailFoxc1 antibodies and methods of their use
In one embodiment, an isolated antibody or functional fragment thereof which binds an antigenic peptide sequence of human foxc1 is provided herein. Such antibodies or functional fragments may be used to diagnose, prognose or treat basal-like breast cancer.
John Wayne Cancer Institute


 Method for controlling cancer metastasis or cancer cell migration by modulating the cellular level of lysyl trna synthetase patent thumbnailMethod for controlling cancer metastasis or cancer cell migration by modulating the cellular level of lysyl trna synthetase
The present invention relates to a novel function of lysyl trna synthetase, that is, lysyl trna synthetase interacts with 67lr through translocation of krs into plasma membrane, and so enhances tumor (or cancer) cell migration, thereby having an effect on cancer metastasis. More specifically, it relates to method for controlling cancer metastasis or cancer cell migration by modulating an cellular level of lysyl trna synthetase, an use of an expression vector comprising a construct inhibiting krs expression for preventing or treating cancer, an use of an agent inhibiting krs activity for preventing or treating cancer, a method for screening an agent which modulates cancer metastasis or cancer cell migration, a method for screening an agent inhibiting an interaction between krs and 67lr.
Medicinal Bioconvergence Research Center


 Devices and methods for prognosis prediction for melanoma cancer patent thumbnailDevices and methods for prognosis prediction for melanoma cancer
The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers.
Ludwig Institute For Cancer Research


 Broad range gene and genotype papillomavirus transcriptome as a biomarker of papillomavirus-associated cancer stages patent thumbnailBroad range gene and genotype papillomavirus transcriptome as a biomarker of papillomavirus-associated cancer stages
The present invention provides compositions, kits, and method for determining the levels of expression of human polyoma or papillomavirus species and rna transcripts. These levels can be used for the prognosis of risk of developing virally-induced cancers.
L'assistance Publique - Hopitaux De Paris


 Biliary tract cancer detection kit or device, and detection method patent thumbnailBiliary tract cancer detection kit or device, and detection method
The present invention provides a kit or device for the detection of biliary tract cancer, and a method for detecting biliary tract cancer. The present invention relates to a kit or device for the detection of biliary tract cancer, comprising a nucleic acid capable of specifically binding to mirna in a sample of a subject, and a method for detecting biliary tract cancer, comprising measuring the mirna in vitro..
National Cancer Center


 Determining cancer aggressiveness, prognosis and responsiveness to treatment patent thumbnailDetermining cancer aggressiveness, prognosis and responsiveness to treatment
The invention provides methods of determining the aggressiveness, prognosis and response to therapy for particular cancers, which include comparing the expression levels of one or a plurality of differentially expressed genes from one or more 5 functional metagenes, including a carbohydrate/lipid metabolism metagene, a cell signalling metagene, a cellular development metagene, a cellular growth metagene, a chromosome segregation metagene, a dna replication/recombination metagene, an immune system metagene, a metabolic disease metagene, a nucleic acid metabolism metagene, a post-translational modification metagene, a protein 10 synthesis/modification metagene and a multiple networks metagene. The method disclosed herein may be particularly suitable as a companion diagnostic for cancer therapies..
The Council Of The Queensland Institute Of Medical Research


 Monomers and oligonucleotides comprising cycloaddition adduct(s) patent thumbnailMonomers and oligonucleotides comprising cycloaddition adduct(s)
In one embodiment, the invention relates compounds and processes for conjugating ligand to oligonucleotide. The invention further relates to methods for treating various disorders and diseases such as viral infections, bacterial infections, parasitic infections, cancers, allergies, autoimmune diseases, immunodeficiencies and immunosuppression..

 Antagonists for abdominal vasopressin v2 receptor and uses thereof patent thumbnailAntagonists for abdominal vasopressin v2 receptor and uses thereof
Provided herein are antagonists or binding agents of an abnormal vasopressin receptor v2 (e.g., abnv2), such as antibodies and antigen-binding portions thereof specific for the receptor, for identifying and targeting cancer cells expressing such abnormal vasopressin receptor v2. Additionally provided are methods of using said antagonists or binding agents, for example, to image cancer cells or in biological samples, or diagnose cancers, both in vivo and in vitro.
Woomera Therapeutics, Inc


Provasopressin antagonists and uses thereof

Provided herein are pro-vp antagonists, such as antibodies and antigen-binding portions thereof specific for pro-vp, for identifying and targeting expressing cancer cells. Applicants additionally provide methods of using said compositions, for example to image cancer cells in vivo and in biological samples.
Woomera Therapeutics, Inc.

Constructs having a sirp-alpha domain or variant thereof

The present disclosure features signal-regulatory protein α (sirp-α) polypeptides and constructs that are useful, e.g., to target a cell (e.g., a cancer cell or a cell of the immune system), to increase phagocytosis of the target cell, to eliminate immune cells such as regulatory t-cells, to kill cancer cells, to treat a disease (e.g., cancer) in a subject, or any combinations thereof. The sirp-α constructs include a high affinity sirp-α d1 domain or variant thereof that binds cd47 with higher affinity than a wild-type sirp-α.
Alexo Therapeutics Inc.

Gemcitabine prodrugs and uses thereof

And pharmaceutically acceptable salts thereof. For compounds of formula i, r1 and r2 are independently selected from the group consisting of h, —c(═o)—(ch2)2-aryl, and —c(═o)—(ch2)n—c(═o)—nh-aryl.

Multi-modal bioprobe for bladder cancer imaging and photodynamic therapy

The present invention relates to a new generation of pdt agents based on porphyrin-lanthanide complexes with specific functional groups which can specifically localize on particular tumors, and their pdt processes can be monitored via nir emission from erbium. In particular, the present invention provides a multi-modal lanthanide-porphyrin pdt agent (er—r3) that are capable of killing the bladder tumor cells selectivity via 1o2 from porphyrin moiety and affording the fluorescence imaging simultaneously upon er—r3 binding with the integrin αvβ3 isoform in bladder cancer cells..
Hong Kong Baptist University

Pharmacophore for trail induction

There are disclosed imidazolinopyrimidinone compounds that have activity to induce trail gene expression in macrophages. There is further disclosed a method for treating various cancers comprising administering effective amounts of an imidazolinopyrimidinone having the structure of formula i herein.
The Scripps Research Institute

Methods involving macrophage tumor cell fusion hybrids

Methods of identifying circulating macrophage-tumor cell fusion hybrids from a subject, methods of screening test compounds for inhibition of activity of in vitro and in vivo derived macrophage-tumor cell fusion hybrids, and methods of assessing the probability of survival of a human subject with pancreatic cancer past one year are disclosed.. .
Oregon Health & Science University

Targeting cancer cells and tissue using filamentous plant virus particles

A filamentous plant virus carrier comprising a filamentous plant virus particle that has been modified to carry an imaging agent or cytotoxic compound is described. The filamentous plant virus carrier can be used in a method of targeting cancer cells and tissue by administering it to a subject.
Case Western Reserve University

Cytokine-chitosan bioconjugates and methods of using the same

Compositions including chitosan covalently linked to a cytokine or growth factor are provided herein. The compositions can be used to produce pharmaceutical compositions and can be used in methods of treating a variety of diseases or disorders.
The Board Of Trustees Of The University Of Arkansas

Cancer treatments

This document provides methods and materials related to treating cancer (e.g., skin cancer). For example, methods and materials relating to the use of a composition containing albumin-containing nanoparticle/antibody complexes (e.g., abraxane®/anti-vegf polypeptide antibody complexes) to treat cancer (e.g., skin cancer) are provided..
Mayo Foundation For Medical Education And Research

Compositions comprising anti-cd38 antibodies and carfilzomib

Disclosed herein are compositions and kits which comprise anti-cd38 antibodies and carfilzomib compounds. Also disclosed are methods for treating cancers, such as multiple myeloma, in subjects with the compositions and kits..
The Regents Of The University Of California

Combinatorial immunotherapy for pancreatic cancer treatment

The invention features compositions and methods for treating and preventing pancreatic cancer.. .
The Johns Hopkins University

Combination of cd95/cd95l inhibition and cancer immunotherapy

The present invention relates to the treatment of cancer using a combination of an inhibitor of the cd95/cd95l signaling system and an immunotherapeutic agent, e.g. A cancer vaccine or a checkpoint inhibitor.
Apogenix Ag

Method for treating drug resistant cancer

The present invention relates to a method for treating a subject with a cancer resistant to a chemotherapeutic drug comprising administering to said subject a therapeutically effective amount of prochlorperazine or its analog or metabolite, or a pharmaceutically acceptable salt thereof, in combination of the chemotherapeutic drug. The present invention also relates to a method for preventing cancer metastasis with the combination of prochlorperazine in combination of a chemotherapeutic drug..
National Yang Ming University

Compounds and methods for the treatment of cancer

Compositions and methods are disclosed in embodiments relating to induction of cell death such as in cancer cells. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed.
The Board Of Trustees Of The University Of Illinois

Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof

Human therapeutic treatment compositions comprise at least two of a curcumin component, a harmine component, and an isovanillin component, and preferably all three in combination. The agents are effective for the treatment of human conditions, especially human cancers..
Ions Pharmaceutical S.à R.i.

Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof

Human therapeutic treatment compositions comprise at least two of a curcumin component, a harmine component, and an isovanillin component, and preferably all three in combination. The agents are effective for the treatment of human conditions, especially human cancers..
Ions Pharmaceutical S.à R.l.

Suppression of undesired 18 fdg uptake within inflammatory lymph nodes and inflamed tissues on positron emission tomography scans that are obtained for neoplastic staging

Positron emission tomography (pet, pet-ct, or pet-mri) scans utilizing 18fdg (fluorodeoxyglucose) are often performed for the evaluation of the extent of neoplastic disease, specifically to assess for the extent of metastases, in order to guide cancer staging and treatment. 18fdg is typically avidly taken up by neoplastic cells, but also by inflamed tissues such as lymph nodes.

Diagnostic device of optics type for breast

The present invention relates to an optical breast diagnostic apparatus taking an image of a breast for diagnosing an abnormality in a female breast, including a hemispherical cover covering the breast with certain spacing; a light source installed inside the hemispherical cover; and a photographing device detachably installed on the hemispherical cover to take an infrared image of the breast. The optical breast diagnostic apparatus has an effect of objectively evaluating the diagnosis of breast cancer by obtaining an image from simple infrared imaging using a camera, without undergoing a complex process such as radiography..
U Biomed Inc.





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This listing is a sample listing of patent applications related to Cancer for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Cancer with additional patents listed. Browse our RSS directory or Search for other possible listings.


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