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|| List of recent Cadaver-related patents
|Methods and materials for producing five carbon building blocks from proline|
This document describes biochemical pathways for producing glutaric acid, 5-aminopentanoic acid, 5-hydroxypentanoic acid, cadaverine or 1,5-pentanediol by forming one or two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a c5 backbone substrate such as d-proline.. .
Invista North America S.á R.l.
|Preparation and producing a preparation comprising mesenchymal stem cells|
Preparation and method for producing a preparation or a tissue derivative that include mesenchymal stem cells, to be used in cellular therapy, for cosmetic treatments, for replacing a tissue or an organ, or inducing or accelerating tissue repair or regeneration. The method includes the steps of extracting tissue containing mesenchymal stem cells, such as adipose tissue, from a cadaveric donor by liposuction or by surgical removal of parts of adipose tissue, and mechanically treating tissue to provide a fluid component, having an oily component, a blood component and/or a sterile solution, and a solid component having cell fragments, cells and one or more cell macro-agglomerates of heterogeneous sizes, thereby separating and removing the fluid component from the solid component, which generates an emulsion of fluid components..
Lipogems International S.p.a.
|Surgical simulation assembly|
A surgical simulation assembly is provided for simulating realistic surgery on animal organs or human cadavers. The surgical simulation assembly comprises a generally flat tray having a central indentation for receiving an organ, at least one drainage aperture and at least one indented trough extending from the central indentation for receiving at least one tube.
|Intervertebral disc repair compositions and methods|
The present invention provides compositions, methods and devices for treatment of degenerative disc disease or the repair of a disc in need of repair. The composition or the formulation includes freshly isolated or culture expanded ela cells, which can be cyropreserved.
Parcell Laboratories, Llc
|Composition containing agmatine, and uses thereof in preparing drugs or neutraceutical substances|
The present invention relates to novel compositions including a mixture of cadaverine, putrescine, spermine and spermidine at a concentration ranging from 0.31 to 0.63 nmol per gram of composition, the composition also including agmatine at a concentration ranging from 120 to 17100 nmol per gram of composition, and uses thereof in the treatment, in a patient, of pathologies associated with cellular hyperproliferation.. .
Nutrialys Medical Nutrition Sa
|Novel synthesis-regulating srna and preparing same|
The present invention relates to a novel customized srna that reduces gene expression in prokaryotic cells, a preparation method thereof, and the use thereof, and more particularly to a synthetic srna comprising an hfq binding site, derived from the srna of any one of micc, sgrs and micf, and a region that base-pairs with the target gene mrna, and to a preparation method thereof and the use thereof. The synthetic srna according to the invention has an advantage in that the degree of inhibition of the target gene can be controlled by regulating the ability of the synthetic srna to bind to the mrna of the target gene.
Korea Advanced Institute Of Science And Technology
|Processes and recombinant microorganisms for the production of fine chemicals|
Recombinant microorganisms with deregulated succinyl-coa synthetase activity, as well as the uses for producing lysine, β-lysine, cadaverine or n-acetylcadaverine thereby are provided. Recombinant polypeptides comprising an amino acid sequence being at least 80% identical to seq id no: 51 or 53 are also provided.
|Intervertebral disc repair, methods and devices therefor|
The present application discloses compositions, methods and devices for treatment of a degenerative intervertebral disc. A composition can comprise chondrocytes expressing type ii collagen.
|Fascia fibrous compositions and methods for their use and manufacture|
Embodiments of the present invention encompass fascia, fat, and dermis fibrous compositions, and methods for their manufacture and use. In a first aspect, embodiments of the present invention encompass methods for obtaining a fascia fiber for use in producing a biotextile.
|Human remains bag with filtration unit|
The present invention is directed to a closeable container for storing a cadaver where the container has a passthrough unit that may allow for filtration and includes an opeanable one-way flow valve that allows for fluids such as gas to travel only from inside the container to the exterior of the container. The passthrough unit includes a coupling for mating with an air purifying canister or cartridge..
Consistent calcium content bone allograft systems and methods
Embodiments of the present invention provides bone graft compositions, and methods for their use and manufacture. A bone graft composition may include a first amount of non-demineralized cancellous bone.
A adhesive composition that includes at least the main components of a hydrolyzable tannin and at least one cationic polymer selected from the group including (poly-)lysine, (poly-)-dl-ornithine, ε-poly-ornithine, (poly-)arginine, (poly-)glutamine, (poly-)asparagine, (poly-)histidine, (poly-)proline, putrescine, spermidine, spermine, cadaverine, agmatine, citrulline and mixtures thereof.. .
Processes and recombinant microorganisms for the production of cadaverine
Recombinant microorganisms comprising dna molecules in a deregulated form which improve the production of cadaverine or n-acetylcadaverine, as well as recombinant dna molecules and polypeptides used to produce the microorganisms are provided. Said microorganisms comprise an intracellular lysine decarboxylase activity and a deregulated cadaverine export activity, or comprise a decreased cadaverine export activity and an enhanced n-acetylcadaverine forming activity.
Minced cartilage systems and methods
Compositions comprising a plurality of cartilage particles from a human adult cadaveric donor, wherein the cartilage particles comprise viable chondrocytes, and a biocompatible carrier are provided. Methods of manufacturing cartilage compositions comprising a plurality of cartilage particles from a human adult cadaveric donor are also provided..
Bone infusion interbody grafts
A bone infusion apparatus for interbody grafts includes a container; a retainer, the retainer including a recess for receiving therein bone graft material; and a lid including a plunger assembly. A method of preparing bone including cadaver bone for use in cervical fusion includes: placing cadaver bone combined with bone collected from a patient into a recess of the retainer; placing the retainer in the container; filling the container with a liquid; attaching a lid the container; depressing a plunger of the lid such that a press head advances toward the retainer causing a dynamic pressure to act on the cadaver bone combined with the bone collected from the patient; suctioning the liquid from the container; removing the combined bone from the retainer; and placing the combined bone removed from the container into a vertebral interspace of the patient..
Method for producing cadaverine
A method of producing cadaverine is more efficient and at a higher yield than production methods by the conventional fermentation methods. The method includes culturing coryneform bacterium/bacteria having a resistance to a ph of 5.5 or less.
Modular staged reality simulator
This invention is directed to a modular staged simulator and a process of simulating medical trauma and maladies for the purpose of training or certifying individuals including medical professionals. More specifically, this disclosure relates to ex vivo training exercises as opposed to traditional forms of training using intact cadavers, in vivo surgery on animal subjects; and supervised apprenticeship performing surgery on human subjects with trauma or maladies under the watch of a skilled medical practitioner..
Method for producing cadaverine
A method produces cadaverine more efficiently and at a higher yield than production methods by the conventional fermentation methods. The method includes culturing coryneform bacterium/bacteria having an ability to produce cadaverine and having a resistance to 2,2′-thiobis(ethylamine).
Stabilized recombinant expression plasmid vector in hafnia alvei and applications thereof
One aspect of the present disclosure relates to a stabilized recombinant expression plasmid vector comprising a polynucleotide encoding an antitoxin gene which expresses a polypeptide that neutralizes a polypeptide toxic to a host cell, the toxic polypeptide being expressed by a toxin gene in the host cell, and a polynucleotide encoding a polypeptide expression product, and the stabilized recombinant expression plasmid vector is derived from a hafnia alvei autonomously replicable backbone plasmid. Other aspects of the present disclosure relate to a transformant transformed with the stabilized recombinant expression plasmid vector disclosed herein, a method of producing biobased cadaverine using the transformant disclosed herein, and biobased cadaverine prepared by the method disclosed herein.
Glycan arrays and methods for their fabrication
The invention relates to glycan arrays with quantified levels of glycan expression and a method for fabricating thereof. The method comprises quantitatively reacting an ω-aminoalkylglycan with an activated polymer of an acrylic acid derivative to obtain glycoconjugated polymer or copolymer and covalently attaching the (co)polymer to a functionalized substrate.
Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
A method of manufacturing a tissue matrix for implantation into a patient is disclosed. The method sets forth collecting embryonic stem cells from a placenta which has been treated to remove residual cord blood and seeding the collected stem cells onto or into a tissue matrix.
Tissue digestion method and apparatus
Tissue digestion methods and apparatuses that provide easy, safe and inexpensive disposal of biological tissue, for example animal carcasses and human cadavers, are disclosed. Embodiments include tissue digesters with elongated cylindrical vessels for holding digestive fluid and baskets for holding tissue within said vessel.
Mutant microorganism having high production of cadaverine, and preparation cadaverine using same
The present invention relates to a mutant microorganism having a high ability to produce cadaverine, and a method for producing cadaverine using the same. More specifically, the invention relates to a mutant microorganism having a high ability to produce cadaverine wherein a gene involved in the cadaverine degradation or utilization pathway is inactivated or deleted, and to a method for producing cadaverine in high yield by culturing the mutant microorganism under aerobic conditions.
Methods for obtaining stem cells
The present invention relates to methods for obtaining stem cells from mammalian cadavers, methods for obtaining or purifying stem cells from a sample likely to contain non-stem cells, methods of regeneration of injured tissues and methods of treatment.. .
Process for production of cadaverine
By a method for producing cadaverine by culturing a microorganism that extracellularly secretes lysine decarboxylase, by-production of lysine is suppressed, the yield of cadaverine relative to glucose consumption is improved compared to conventional production methods, and further, the load on the purification step in purification of cadaverine as a raw material for polyamide can be reduced.. .
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Cadaver topics: Cadaverine, Stem Cells, Fluorescent Label, Quantitative, Embryonic Stem Cell, Implantation, Completeness, Circulation, Extracellular, Sequencing, Transgenic Plants, Transgenic, Recombinant Dna Molecules, Dna Molecules, Pesticides
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