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Bronchopulmonary

Bronchopulmonary-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Use of tgf-beta antagonists to treat infants at risk of developing bronchopulmonary dysplasia
The General Hospital Corporation
August 17, 2017 - N°20170233464

The disclosure relates to methods of treating an infant at risk of developing bronchopulmonary dysplasia, including premature infants, by administering a tgf-β antagonist during the perinatal period, including the prenatal period and/or the postnatal period. For administration during the prenatal period, the tgf-β antagonist can be administered either directly to the infant in utero, or ...
Method for using supplemental vascular endothelial growth factor (vegf) or analog to prevent oxygen induced ...
The General Hospital Corporation
August 10, 2017 - N°20170224774

Disclosed herein is a method for administering systemic (e. G., by intravenous injection) supplemental vascular endothelial growth factor (vegf) to premature infants to prevent the disease sequelae and complications including but not limited to retinopathy of prematurity (rop) and/or paraventricular leukomalacia (pvl) and/or bronchopulmonary dysplasia (bpd) associated with premature births. The vegf is administered to the premature infant ...
Method of identifying and treating premature infants at risk for bpd
Ino Therapeutics Llc
July 27, 2017 - N°20170212133

Methods for identifying premature infants at risk for developing bronchopulmonary dysplasia and/or most likely to benefit from administration of inhaled nitric oxide for prevention of bronchopulmonary dysplasia (bpd). Methods for treating premature infants identified as at risk and/or likely to benefit are provided. Also provided are methods for identifying premature infants that are not at risk for developing ...
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Humanized anti-ige antibodies that crosslink cd23 on b lymphocytes but do not sensitize mast cells
Academia Sinica
May 04, 2017 - N°20170121425

A novel humanized anti-ige antibody is disclosed. The antibody is capable of binding to free ige, membrane-bound ige on b lymphocytes, ige bound by cd23, but not to ige bound by high-affinity ige. Fc receptor on mast cells. The present invention relates to the treatment of ige-mediated diseases, including allergic asthma, allergic rhinitis, atopic dermatitis, food allergy, chronic spontaneous (idiopathic) ...
New treatment
Verona Pharma Plc
April 27, 2017 - N°20170112839

The invention provides a compound for use in treating or preventing a disease or condition selected from cystic fibrosis, chronic obstructive pulmonary disease (copd), asthma, mild pulmonary disease, bronchitis, bronchiectasis, idiopathic bronchiectasis, allergic bronchopulmonary aspergillosis, sinusitis, rhinosinusitis, cftr-related metabolic syndrome (crms), pancreatitis, idiopathic chronic pancreatitis and sjörgren's syndrome, or for use in preventing male infertility caused by congenital ...
Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof
Verona Pharma Plc
January 19, 2017 - N°20170014369

Such compositions can also further comprise various components such as lipids (for example fatty acids, esters thereof or derivatives thereof). Such compositions can be used for example in methods for treating an inflammatory diseases chosen from inflammatory bowel diseases, asthma, acute respiratory distress syndrome, chronic obstructive pulmonary disease, acute lung injury, bronchopulmonary dysplasia, cystic fibrosis, bronchitis, bronchiolitis, arthritis, osteoarthritis, ankylosing ...
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Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
Lutonix, Inc.
October 20, 2016 - N°20160303091

Embodiments of the present invention provide a method for treatment of respiratory disorders such as asthma, chronic obstructive pulmonary disease, and chronic sinusitis, including cystic fibrosis, interstitial fibrosis, chronic bronchitis, emphysema, bronchopulmonary dysplasia and neoplasia. The method involves administration, preferably oral, nasal or pulmonary administration, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and an additive.
Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
Lutonix, Inc.
September 01, 2016 - N°20160250195

Embodiments of the present invention provide a method for treatment of respiratory disorders such as asthma, chronic obstructive pulmonary disease, and chronic sinusitis, including cystic fibrosis, interstitial fibrosis, chronic bronchitis, emphysema, bronchopulmonary dysplasia and neoplasia. The method involves administration, preferably oral, nasal or pulmonary administration, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues).
Methods and compositions for the reduction of neutrophil influx and the treatment of bronchopulmonary displasia, ...
Therabron Therapeutics, Inc.
August 25, 2016 - N°20160243193

The present invention relates generally to the use of recombinant human cc10 (rhcc10), also known as recombinant human uteroglobin, for use as a therapeutic in the treatment of respiratory distress syndrome (rds), bronchopulmonary dysplasia (bpd), chronic lung disease and/or pulmonary fibrosis, asthma and chronic obstructive pulmonary disease (copd). More particularly, the invention provides methods, including broadly the critical dosage ...
Transdermal administration system for use in the treatment of chronic bronchopulmonary diseases
Therabron Therapeutics, Inc.
June 30, 2016 - N°20160184312

Transdermal administration system comprising doxofylline as the active ingredient, for use in the treatment of bronchopulmonary diseases having a broncho-obstructive component.
Compositions and methods of inhibiting gene expression in a lung
Yale University
December 24, 2015 - N°20150368648

The present invention provides compositions and methods for delivery to a lung tissue comprising a small interfering rna (sirna) capable of inhibiting expression of a gene, and a surfactant. In one aspect, a non-polymeric methods composition comprising a small interfering rna (sirna) capable of inhibiting expression of a gene, and a surfactant is disclosed. In other aspects, a method of ...
Surfactant protein d for the treatment of disorders associated with lung injury
Children's Hospital Medical Center
July 02, 2015 - N°20150182599

Surfactant protein d (sp-d) is a 43-kda member of the collectin family of collagenous lectin domain-containing proteins that is expressed in epithelial cells of the lung. Described herein are methods and compositions for the treatment of disorders associated with lung injury, including methods and compositions for the treatment of bronchopulmonary disorder (bpd) using recombinant human surfactant protein d and surfactant ...
Methods for treating inflammatory diseases with compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof
Scf Pharma Inc.
February 26, 2015 - N°20150057348

There are provided methods for treating an inflammatory diseases chosen from inflammatory bowel diseases, asthma, acute respiratory distress syndrome, chronic obstructive pulmonary disease, acute lung injury, bronchopulmonary dysplasia, cystic fibrosis, bronchitis, bronchiolitis, arthritis, osteoarthritis, ankylosing spondylitis and rheumatism. The method comprise administering to a subject in need thereof an effective amount of at least one lipid and an effective amount ...
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Use of tgf-beta antagonists to treat infants at risk of developing bronchopulmonary dysplasia
Scf Pharma Inc.
July 17, 2014 - N°20140199399

The disclosure relates to methods of treating an infant at risk of developing bronchopulmonary dysplasia, including premature infants, by administering a tgf-β antagonist during the perinatal period, including the prenatal period and/or the postnatal period. For administration during the prenatal period, the tgf-β antagonist can be administered either directly to the infant in utero, or ...
Surfactant protein d for the treatment of disorders associated with lung injury
Scf Pharma Inc.
May 15, 2014 - N°20140135268

Surfactant protein d (sp-d) is a member of the collectin family of collagenous lectin domain-containing proteins that is expressed in epithelial cells of the lung. Described herein are methods and compositions for the treatment of disorders associated with lung injury, including methods and compositions for the treatment of bronchopulmonary disorder (bpd).
Detecting, preventing, and treating bronchopulmonary dysplasia
Scf Pharma Inc.
May 08, 2014 - N°20140127232

Provided herein are methods for preventing or treating bronchopulmonary dysplasia (bpd) in a subject. The methods comprise identifying connective tissue mast cells (ctmcs) in a subject and administering an agent that blocks an activity of blocks an increase in a level of or reduces a level of the ctmcs in the subject. Also provided are methods of identifying a subject ...
Solid ambroxol-containing preparation
Scf Pharma Inc.
April 03, 2014 - N°20140094523

The present invention relates to solid preparations containing ambroxol which are obtainable by melt extrusion of the mixture consisting of a) 30 to 80% by weight of ambroxol hydrochloride, b) 2 to 68% by weight of at least one hydrogenated vegetable oil, c) 2 to 68% by weight of at least one mixture containing fatty acid ester and/or hydroxy fatty acid ester and d) 0 to 66% ...
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