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Bronchi

Bronchi-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Compound for treating respiratory syncytial virus infection and preparation method and use thereof
Shandong University
April 05, 2018 - N°20180094021

The present invention declares a kind of compound to treat respiratory syncytial virus infection and its preparation method and application. The compound stated is cyclopamine's chemical analogs, has the property of inhibiting respiratory syncytial virus replication, and does not have the property of inhibiting hedgehog signaling pathways. The preparation method stated is to get the cyclopamine's chemical analogs through drug ...
Medical tubes for selective mechanical ventilation of the lungs
April 05, 2018 - N°20180093058

A single lumen endobronchial tube for selective mechanical ventilation of the lungs can include a medical tube having a single lumen with an opening at each of opposed distal and proximal ends of the tube, the opening at the proximal end of the tube being adapted for connection to an external mechanical ventilation device, and the opening at the distal ...
Pyrazolothiazole compound and medicine comprising same
April 05, 2018 - N°20180092919

The compound of the invention has jak1 inhibitory activity, and thus, immunosuppressive effect, anti-inflammatory effect and anti-proliferative effect, and is useful in the treatment of the diseases, for example, rheumatoid arthritis, inflammatory bowel disease, psoriasis and vasculitis, bronchial asthma, chronic obstructive pulmonary disease and eosinophilic sinusitis, nasal polyp.
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System and method for cleansing segments of a luminal network
Covidien Lp
March 22, 2018 - N°20180078119

A method and system for instilling a medium into portions of a luminal network is provided. The method includes generating a model of a luminal network based on images of the luminal network, determining a location of a treatment target in the luminal network, navigating a bronchoscope through the bronchial tree to a target, guiding a catheter through the bronchoscope, ...
Compositions and methods for treating asthma and other lung diseases
The Trustees Of The University Of Pennsylvania
March 15, 2018 - N°20180071233

The present invention provides methods for dilating the bronchi or bronchioles and relaxing a pulmonary smooth muscle in a subject by treating the subject with a pharmaceutical composition, which includes a histone deacetylase (hdac) inhibitor. The ability to dilate the bronchi or bronchioles and relax a pulmonary smooth muscle according to the methods of the invention allows treating, alleviating, or ...
Ibv strains and uses thereof
Biomune Company
March 08, 2018 - N°20180066236

The present invention relates to novel infectious bronchitis virus strains and the uses thereof. The invention particularly relates to an inactivated or attenuated ibv, as well as to vaccine compositions comprising the same and the uses thereof to vaccinate avians. The invention also relates to nucleic acids, infected cells and methods for detecting the infectious bronchitis virus strains of the ...
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Methods of treatment of eosinophilic bronchitis with an anti-il-5 antibody
Glaxosmithkline Llc
March 01, 2018 - N°20180057582

The present invention relates generally to the methods for the treatment and diagnosis of conditions mediated by il-5 and excess eosinophil production, and more specifically to mabs, fabs, chimeric and humanized antibodies. More particularly, the present invention relates generally to the treatment of eosinophilic bronchitis with an anti-il-5 antibody or fragment thereof.
Use of alginate oligomers and cftr modulators in the treatment of conditions associated with cftr ...
Algipharma As
March 01, 2018 - N°20180055873

A method is for the treatment of a condition in a subject, which arises from or is associated with cftr dysfunction. The method includes administering to the subject an effective amount of a cftr modulator together with an effective amount of an alginate oligomer. The condition can be cystic fibrosis (cf), non-compound cftr gene mutation heterozygosity, abnormal mucus clearance in ...
Mint mask and methods of use thereof
Georgetown University
March 01, 2018 - N°20180055785

Provided are methods and devices useful for treating a respiratory disease or disorder involving the central or upper airways. The methods and devices deliver to central or upper airways of a subject a vapor or aerosol comprising an effective amount of an active ingredient selected from the group consisting of menthol, menthone, neomenthol, isomenthol, and menthofuran. The methods are useful ...
Compositions for use in the prevention or treatment of otitis or bronchitis in infants or ...
Nestec S.a.
February 15, 2018 - N°20180042949

The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide and at least one n-acetylated oligosaccharide in particular amounts, for use in preventing and/or treating infections and/or inflammations of the lower respiratory tract and/or of the ear in an infant or a young child.
Composition and method for treating acute respiratory tract infections
Glycom A/s
February 08, 2018 - N°20180036327

A composition and method for using it to prevent and/or relieve symptoms of acute respiratory tract infections, particularly bronchitis, in immune-compromised persons, particularly adults. The composition contains 2′-fucosyllactose and lacto-n-neotetraose and/or lacto-n-tetraose.
Illumination systems and devices for tracheal tubes
Covidien Lp
February 08, 2018 - N°20180035912

Various embodiments of an intubation system include a tracheal tube and an illumination assembly that is removably couplable to a tubular body of the tracheal tube. The tracheal tube may be a double lumen tracheal tube having a first cuff that is adapted to be inflated to seal against the walls of a patient's trachea and a second cuff that ...
Apparatus for treating asthma using neurotoxin
Nuvaira, Inc.
February 01, 2018 - N°20180028748

Apparatus for providing intrabronchial delivery of neurotoxins to control the effects of asthma comprises a shaft having proximal and distal ends and a neurotoxin applicator assembly disposed on the distal end. The neurotoxin applicator assembly comprises a deployable needle assembly, a rotating needle assembly, and a needle-less injection assembly or a nebulizer assembly.
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Method for preparing pluripotent stem cells
Otsuka Pharmaceutical Factory, Inc.
January 18, 2018 - N°20180016549

An object of the present invention is to provide a method capable of inexpensively and conveniently preparing cells having pluripotency and a very low risk of tumorigenic transformation. The cells can be prepared by suspension-culturing mammalian mesenchymal stem cells such as human mesenchymal stem cells from bone marrow (hmsc-bm) and human adipose tissue-derived mesenchymal stem cells (hat-msc) (also referred to ...
Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions
Trustees Of Boston University
January 11, 2018 - N°20180010197

Disclosed herein are assays and methods for the identification of premalignant lesions, as well as methods of determining the likelihood that such premalignant lesions will progress to lung cancer. Also disclosed are methods and assays that are useful for monitoring the progression of premalignant lesions to lung cancer. The assays and methods disclosed herein provide minimally invasive means of accurately ...
Adaptation of attenuated infectious bronchitis virus (ibv) to embryonic kidney cells and vaccine thereby produced
Auburn University
January 11, 2018 - N°20180008698

Disclosed are methods for preparing a vaccine against infection by infectious bronchitis virus (ibv). The methods typically include passing a heterogeneous attenuated population of ibv in chicken embryonic kidney cells, and optionally may include further passaging the heterogeneous attenuated population of ibv in embryonated chicken eggs (ece) in order to obtain passaged attenuated population of ibv. Also disclosed are passaged ...
System and method for navigating within the lung
Covidien Lp
January 11, 2018 - N°20180008212

Methods and systems for navigating to a target through a patient's bronchial tree are disclosed including a bronchoscope, a probe insertable into a working channel of the bronchoscope and including a location sensor, and a workstation in operative communication with the probe and the bronchoscope, the workstation including a user interface that guides a user through a navigation plan and ...
Composition for prevention or treatment of bronchial asthma comprising pkr inhibitor as active ingredient
Chonbuk National University Hospital
January 04, 2018 - N°20180000794

The present invention relates to a composition for prevention or treatment of bronchial asthma comprising a pkr inhibitor as an active ingredient. The pkr inhibitor and derivatives thereof according to the present invention can be used as a pharmaceutical for prevention, amelioration or treatment of bronchial asthma and as a supplementary health food because the pkr inhibitor and derivatives thereof ...
Derivatives of 5-phenyl- or 5-heteroarylathiazol-2-carboxylic amide useful for the treatment of inter alia cystic ...
Proteostasis Therapeutics, Inc.
December 28, 2017 - N°20170369482

The present disclosure is based, in part, on the discovery that disclosed compounds such as those having formula (iiia), (iii), or (iv) can increase cystic fibrosis transmembrane conductance regulator (cftr) activity as measured in human bronchial epithelial (hbe) cells.
Compounds, compositions, and methods for increasing cftr activity
Proteostasis Therapeutics, Inc.
December 28, 2017 - N°20170369480

The present disclosure is directed to disclosed compounds that increase cystic fibrosis transmembrane conductance regulator (cftr) activity as measured in human bronchial epithelial (hbe) cells.
Novel compound and antiviral agent containing same as active ingredient
National University Corporation Chiba University
December 28, 2017 - N°20170368015

An object of the invention is to provide a compound that can be utilized as an antiviral agent, in particular as an anti-rna viral agent, and especially as an anti-rs viral agent. The invention provides a compound indicated by formula (1), wherein r1 each independently represent hydrogen, halogen, hydroxyl, amino, carboxyl, c1-c6 alkyl, c1-c6 alkoxyl, c1-c6 halogenoalkyl, c1...
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