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Bowel patents



      
           
This page is updated frequently with new Bowel-related patent applications. Subscribe to the Bowel RSS feed to automatically get the update: related Bowel RSS feeds. RSS updates for this page: Bowel RSS RSS


Date/App# patent app List of recent Bowel-related patents
12/11/14
20140364604
 Method of making monomethyl fumarate patent thumbnailMethod of making monomethyl fumarate
Methods of making monomethyl fumarate, which can then also be used in methods of making prodrugs of monomethyl fumarate, are disclosed. Monomethyl fumarate and prodrugs of monomethyl fumarate are useful for treating neurodegenerative, inflammatory, and autoimmune diseases including multiple sclerosis, psoriasis, irritable bowel disorder, ulcerative colitis, arthritis, chronic obstructive pulmonary disease, asthma, parkinson's disease, huntington's disease, and amyotrophic lateral sclerosis..
12/11/14
20140364373
 Novel enteric combination therapy patent thumbnailNovel enteric combination therapy
There is disclosed herein a composition for treating gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers' diarrhoea, chronic idiopathic nausea, ibd-associated constipation and diarrhoea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, parkinson's disease, ms, alzheimer's disease, motor neurone disease or autism, the composition comprising: (i) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (ii) at least one anti-clostridial agent selected from the above combined with an opioid blocking agent. There is also disclosed herein a method of treating various gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers' diarrhoea, chronic idiopathic nausea, ibd-associated constipation and diarrhoea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, parkinson's disease, ms, alzheimer's disease, motor neurone disease or autism, the method comprising administering orally, via enema or by suppository: (i) a composition of the invention; (ii) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (iii) at least one anti-clostridial agent selected from the above and an opioid blocking agent to a patient in need of such treatment..
12/11/14
20140363673
 Therapeutic agent for inflammatory bowel disease patent thumbnailTherapeutic agent for inflammatory bowel disease
The present invention provides a therapeutic and/or prophylactic agent for inflammatory bowel disease and an nf-kb activation inhibitor, each of which comprises chitin nanofibers or chitosan nanofibers.. .
12/11/14
20140363397
 Method for treatment of disorders of the gastrointestinal system patent thumbnailMethod for treatment of disorders of the gastrointestinal system
There are provided novel synthetic stool preparations comprising bacteria isolated from a fecal sample from a healthy donor. The synthetic stool preparations are used for treating disorders of the gastrointestinal tract, including dysbiosis, clostridium difficile infection and recurrent clostridium difficile infection, prevention of recurrence of clostridium difficile infection, treatment of crohn's disease, ulcerative colitis, irritable bowel syndrome, inflammatory bowel disease, and diverticular disease, and treatment of food poisoning such as salmonella.
12/04/14
20140357655
 Spiroindoline derivatives as gonadotropin- releasing hormone receptor antagonists patent thumbnailSpiroindoline derivatives as gonadotropin- releasing hormone receptor antagonists
Spiroindoline derivatives, process for their preparation and pharmaceutical compositions thereof, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially sex-hormone-related diseases in both men and women, in particularly those selected from the group of endometriosis, uterine fibroids, polycystic ovarian disease, hirsutism, precocious puberty, gonadal steroid-dependent neoplasia such as cancers of the prostate, breast and ovary, gonadotrope pituitary adenomas, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hypertrophy, contraception and infertility (e.g., assisted reproductive therapy such as in vitro fertilization). The present application relates in particular to spiroindoline derivatives as gonadotropin-releasing hormone (gnrh) receptor antagonists..
12/04/14
20140356316
 Amine polymers for use as bile acid sequestrants patent thumbnailAmine polymers for use as bile acid sequestrants
The present invention provides crosslinked amine polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical compositions thereof can be administered to subjects to treat various conditions, including hypercholesteremia, diabetes, pruritus, irritable bowel syndrome-diarrhea (ibs-d), bile acid malabsorption, and the like..
11/27/14
20140350384
 Apparatus and method for use in analyzing a patient's bowel patent thumbnailApparatus and method for use in analyzing a patient's bowel
An apparatus and method are provided for use in studying a patient's bowel which combines recording and analysis of physiologic parameters and patient sensory perception. A pain input detector, a pain transducer, and a processor are provided.
11/27/14
20140349986
 Substituted aminoindanes and analogs thereof, and the pharmaceutical use thereof patent thumbnailSubstituted aminoindanes and analogs thereof, and the pharmaceutical use thereof
And the pharmaceutical use thereof. Medicaments which comprise compounds of this type are suitable for the prevention or treatment of diverse disorders such as, for example, of respiratory disorders, cystic fibrosis disorders, acute or chronic renal disorders or bowel disorders..
11/27/14
20140348942
 Treatments for gastrointestinal disorders patent thumbnailTreatments for gastrointestinal disorders
The present invention provides pharmaceutical compositions and methods of treating lower gastrointestinal disorders, including inflammatory bowel disease (ibd), diverticulitis, colon cancer, an inflammatory disorder, obesity, congestive heart failure, benign prostatic hyperplasia (bph), pain, salt retention or fluid retention.. .
11/20/14
20140343110
 Uses of 4'-desferrithiocin analogs patent thumbnailUses of 4'-desferrithiocin analogs
Macular degeneration, closed head injury, stroke, irritable bowel disease, and reperfusion injury are all associated with biological injury due to reactive oxygen species, probably due to focal iron overload in many instances. The present invention provides methods and pharmaceutical compositions for treating these diseases and conditions using desferrithiocin analogs of formula (i).
11/20/14
20140342996
Treatments for gastrointestinal disorders
The present invention provides pharmaceutical compositions and methods of treating lower gastrointestinal disorders, including irritable bowel syndrome and constipation.. .
11/20/14
20140342988
Adrenomedullin and adrenomedullin binding protein for ischemia/reperfusion treatment
Methods of treating a mammal at risk for ischemia-reperfusion injury are provided. The methods comprise administrating an adrenomedullin binding protein-1 (ambp-1) to the mammal in sufficient amount to reduce the injury.
11/13/14
20140336604
Devices and methods for treating accidental bowel leakage
Described here are body liners and methods for treating accidental bowel leakage using one or more body liners. The body liners may be formed from one or more liner layers and in some instances may comprise one or more adhesive regions to connect the body liners to the skin of a wearer.
11/13/14
20140336569
Device for the trans-anal drainage of stool from the rectum of a patient and/or for the trans-anal application of inflowing liquid through a catheter-like element
A device for emptying stool from the rectum of a patient by means of a shaft body which is introduced into the bowel via the anus and is able to buckle or fold axially and radially, and which is provided with a dumbbell- or hourglass-shaped balloon body for assuring the transanal positioning of the device. The invention comprising a design of, and choice of material, for the shaft body and the balloon envelope, and by the positioning of the balloon body on the shaft body, wherein the axial deflection of the free forward end of the shaft body is limited and an uncontrolled deflection of the shaft is prevented, and the probability of perforation of the bowel wall under the effect of force acting on the shaft body from an axial direction is reduced by the intestinal tube..
11/13/14
20140336119
Polypeptides targeting glycosylated muc2 proteins, methods of synthesis, their nucleic acids and uses thereof
The invention relates to polypeptides, defined through a consensus sequence, having a length from 10 to 80 amino-acid residues, and whose polypeptidic sequence comprises or consists of the consensus sequence p1(xa)p3(xb)p5(xc)p6(xd)p7 (seq id no: 1), presenting specific patterns. The polypeptides of the invention target glycosylated muc2 proteins.
11/13/14
20140335205
Materials and methods for treatment of disorders associated with oxidative stress
The subject invention pertains to materials and methods for the prevention and treatment of disease conditions associated with oxidative stress or a compromised reducing environment, including inflammatory bowel diseases such as crohn's disease and ulcerative colitis. Therapeutic compositions of the invention include compositions that can neutralize hydrogen peroxide, such as reducing agents and oxidizing agents.
11/06/14
20140330068
Method for modulating the enteric nervous system to treat a disorder
Non-invasive and/or natural orifice procedures, apparatus and methods for modulating the enteric nervous system using one or more energy modalities. A system may include a probe for insertion into a natural orifice (e.g., nasogastrically, orogastrically, nasojejunally) with or without a tube to therapeutically apply energy to modulate one or more portions of the enteric nervous system.
11/06/14
20140329818
Methods of using prodrugs of methyl hydrogen fumarate and pharmaceutical compositions thereof
Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions comprising prodrugs of methyl hydrogen fumarate, and methods of using prodrugs of methyl hydrogen fumarate and pharmaceutical compositions thereof for treating diseases such as psoriasis, asthma, multiple sclerosis, inflammatory bowel disease, and arthritis are disclosed.. .
11/06/14
20140329799
Aminopyrimidinones as interleukin receptor-associated kinase inhibitors
This invention relates to aminopyrimidinone compounds of formula (i) that are inhibitors of interleukin receptor-associated kinases, in particular irak-4, and are useful in the treatment or prevention of inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease.. .
11/06/14
20140329765
Methods and compositions for the treatment of gastrointestinal disorders
Compositions and related methods for treating ibs and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (gerd), duodenogastric reflux, crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase c (gc-c) receptor..
11/06/14
20140329738
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
The invention provides novel guanylate cyclase-c agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cgmp-dependent phosphodiesterase.
11/06/14
20140328934
Granules for pharmaceutical preparations, methods and apparatus for their production
Disclosed are improved granular pharmaceutical preparations, together with improved methods and apparatus for preparation of granules for use in such preparations. Such methods are especially useful for making granules for solid oral dose pharmaceutical preparations, and are particularly suited to the production of granules comprising 5-aminosalicylic acid (5-asa) for the treatment of inflammatory bowel disease.
11/06/14
20140328879
Probiotic bifidobacterium strains
Probiotic bifidobacterium strain ah1205 or mutants or variants thereof are immunomodulatory following oral consumption and are useful in the prophylaxis and/or treatment of inflammatory activity such as undesirable gastrointestinal inflammatory activity for example inflammatory bowel disease.. .
11/06/14
20140328859
Antibodies and methods for wnt pathway-related diseases
The transmembrane e3 ubiquitin ligases znrf3 and rnf43 are negative regulators of β-catenin and the wnt signaling pathway in eukaryotic cells. The activity of znrf3 can be modulated by antibody binding to its extracellular domain, thus causing an increase in wnt signaling.
11/06/14
20140328808
Technique for isolating/culturing colorectal epithelial stem cell, and technique for transplanting colorectal epithelium employing said technique
It is an object of the present invention to provide a culture medium for in vitro culture of a colorectal epithelial stem cell or the like, a method of in vitro culturing a colorectal epithelial stem cell or the like using the culture medium, a prophylactic or therapeutic agent for a bowel disease containing a colorectal epithelial stem cell or the like cultured by the method, a method of administrating, i.e., transplanting a colorectal epithelial stem cell or the like cultured by the method to a bowel disease patient, and a method of isolating a colorectal epithelial stem cell or the like. The culture medium for in vitro culture of a colorectal epithelial stem cell and/or a colorectal epithelial cell characteristically contains serum albumin, wnt3a, and r-spondin-1..
10/30/14
20140323534
Uses of 3'-desferrithiocin analogs
Macular degeneration, closed head injury, stroke, irritable bowel disease, and reperfusion injury are all associated with biological injury due to reactive oxygen species, probably due to focal iron overload in many instances. The present invention provides methods and pharmaceutical compositions for treating these diseases and conditions using desferrithiocin analogs of formula (i).
10/30/14
20140322302
Therapeutic peptides
Therapeutic peptides having guanylyl cyclase c agonist activity are disclosed. The therapeutic peptides are analogues of the e.
10/30/14
20140322278
Modulation of tissue transglutaminase activation in disease
Compositions and methods are provided for modulating the physiological activation of tissue transglutaminase (tg2); which methods can include inhibiting the activation of tg2 associated with enteric inflammatory disorders, which disorders may include celiac disease, irritable bowel syndrome, crohn's disease, dermatitis herpetiformis, and the like. In other embodiments of the invention, methods are provided for reducing undesirable paracellular transport in enteric tissues, in particular the paracellular transport of molecules greater than about 500 mw, e.g.
10/23/14
20140315888
Novel heterocyclic derivatives and their uses
The present invention relates to novel heterocyclic compounds useful in preparing drugs for treatment of diseases associated with various functions of the histamine 4 receptor. Especially, the said drugs are useful for treatment of inflammatory diseases, allergy, pain, nasal polyps, rhinitis, chronic sinusitis, nasal congestion, nasal itch, asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, atopic dermatitis, psoriasis, eczema, pruritus, itchy skin, urticaria, idiopathic chronic urticaria, scleroderma, conjunctivitis, keratoconjunctivitis, ocular inflammation, dry eye, cardiac dysfunction, arrhythmia, atherosclerosis, multiple sclerosis, inflammatory bowel disease (including colitis, crohn's disease, ulcerative colitis), inflammatory pain, neuropathic pain, osteoarthritic pain, autoimmune thyroid disease, immune-mediated (also known as type i) diabetes, lupus, post-operative adhesions, vestibular disorders and cancer..
10/23/14
20140315849
Therapeutic agent for inflammatory diseases, containing adenosine n1-oxide as an effective ingredient
The present invention has an object to provide an effective and safe therapeutic agent for inflammatory diseases such as sepsis, hepatitis, and inflammatory bowel disease, and solves the above object by providing a therapeutic agent for inflammatory diseases containing adenosine n1-oxide or a derivative thereof as an effective ingredient.. .
10/23/14
20140315846
Andrographis paniculata extract
An extract of andrographis paniculata extract containing androgapholide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysaccharides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease..


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Bowel topics: Bowel Disease, Inflammatory Bowel Disease, Irritable Bowel Syndrome, Inflammation, Mercaptopurine, Probiotics, Abdominal Pain, Discomfort, Bowel Movement, Gastrointestinal, Ulcerative Colitis, Rheumatoid Arthritis, Jejunal Tube, Spring Mechanism, Small Bowel

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