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Sponge sheath for laparoscopic aspirator
|| List of recent Bowel-related patents
| Role of ifng methylation in inflammatory bowel disease|
The invention relates to method of diagnosing susceptibility to inflammatory bowel disease (ibd) in an individual by obtaining a sample from the individual, assaying the sample to determine the presence or absence of one or more risk genetic variants and/or an increase in ifng dna methylation. In one embodiment, the present invention provides a method of diagnosing susceptibility to inflammatory bowel disease (ibd) in an individual by obtaining a sample from the individual, assaying the sample to determine the presence or absence of one or more risk genetic variants and/or an increase in ifng dna methylation relative to a normal subject, and diagnosing susceptibility to inflammatory bowel disease based on the presence of one or more risk genetic variants and/or an increase in ifng dna methylation relative to a normal subject.
Cedars-sinai Medical Center
|Sponge sheath for laparoscopic aspirator|
The present invention relates to the aspirators, one of the hand tools used in laparoscopic surgery. In the present invention, a sponge sheath that can be fitted on the known aspirator tip structure in order to prevent blockage that may occur in the aspirators by adherence of the bowel and omentum during the aspiration of the interior of the abdomen..
|Deuterium-enriched pyridinonecarboxamides and derivatives|
Are partial or full agonists of serotonin (5-hydroxytryptamine or 5-ht) receptor subtype 4 (5-ht4), and are useful compounds for the prevention and treatment of alzheimer's disease, cognitive and memory dysfunction, mild cognition impairment, memory decline, cognitive impairment associated with schizophrenia, cognitive impairment associated with age-related dementia or alzheimer's disease, cognitive impairment associated with post-coronary bypass surgery, attention deficit hyperactivity disorder, obsessive compulsive disorder, depression, speech improvement in autistic children, sleep apnea in alzheimer's patients, age-related macular degeneration (amd), irritable bowel syndrome, gastroesophageal reflux disease, crohn's disease, emesis, nausea, vomiting, prokinesia, non-ulcer dyspepcia, anxiety, depression, pain, migraine, urinary incontinence, arterial fibrillation, arrhythmia, ischemic stroke, gastric emptying disorders, gastritis, gastrointestinal disorders, feeding disorders, obesity, anorexia, constipation, respiratory depression, and erectile dysfunction.. .
|Chinese medicinal formulation for treating inflammatory bowel disease and the preparation thereof|
This invention relates to a chinese medicinal formulation for the treatment of inflammatory bowel diseases, and a method of preparation thereof. The formulation comprises herbal components selected from a group consisting of radix codonopsis (dangshen), rhizoma atractylodis macrocephalae (bai zhu), sclerotium poriae cocos (fu ling), rhizoma zingiberis officinalis (gan jiang), radix paeoniae alba (bai shao) and rhizoma coptidis (huanglian)..
Hong Kong Baptist University
|Recombinant probiotic bacteria for the prevention and treatment of inflammatory bowel disease (ibd) and irritable bowel syndrome (ibs)|
The present invention relates to the general field of therapy of inflammatory bowel disease (ibd) and/or irritable bowel syndrome (ibs). Thus, the invention relates to a molecule selected from the trappin-2 protein or an active fraction thereof, a member of the wap family proteins or an active fraction thereof or a member of the serpin family proteins or an active fraction thereof for the treatment of irritable bowel syndrome (ibs).
Universite Paris Diderot - Paris 7
|Novel cholesterol metabolite, 5-cholesten, 3beta-25-diol, disulfate (25hcds) for therapy of metabolic disorders, hyperlipidemia, diabetes, fatty livers diseases and atherosclerosis|
5-cholesten, 3β, 25-diol, disulfate (25hcds) has been found to be an authentic pparγ agonist and lxr antagonist, and is used for the therapy of lipid disorders and inflammatory diseases, including without limitation fatty liver, inflammatory bowel, and atherosclerotic diseases.. .
Virgini Commonwealth University
|Methods for improving inflammatory bowel disease diagnosis|
The present invention provides methods and systems to predict and diagnose inflammatory bowel disease (ibd) and subtypes such as ulcerative colitis (uc) and crohn's disease (cd) by detecting the presence, absence, level, and/or genotype of one or more sero-genetic-inflammation markers. Advantageously, with the present invention, it is possible to provide a diagnosis of ibd versus non-ibd, to rule out ibd that is inconclusive for cd and uc, and to differentiate between cd and uc with increased accuracy..
|Pharmaceutical compositions of sodium picosulfate, magnesium oxide and citric acid|
The present invention relates to pharmaceutical compositions of sodium picosulfate, magnesium oxide and citric acid. In particular, the invention relates to pharmaceutical compositions comprise granules having a layer of sodium picosulfate on neutral carrier/s.
Cadila Healthcare Limited
|Intraluminal occluding catheter|
An intraluminal occluding catheter and method for preventing the loss of gas insufflation from a physiological lumen during a medical procedure is presented. The intraluminal occluding catheter is generally comprised of a catheter shaft having a flexible balloon affixed on a distal intraluminal end and a plurality of independent channels extending through the catheter shaft from the external proximal end to the distal intraluminal end.
University Of South Florida
|Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer|
The present invention provides methods for preventing colon cancer by administering, to a patient in need thereof, a polymeric proanthocyanidin composition from a croton species or calophyllum species in an amount sufficient to prevent colon cancer, which composition inhibits cox-2. The present invention also provides methods for treating inflammation locally in the intestines comprising administering to a patient in need thereof, a polymeric proanthocyanidin composition from a croton species or calophyllum species in an amount sufficient to treat inflammation.
Biomarker associated with irritable bowel syndrome and crohn's disease
The present invention provides compositions and methods for characterizing irritable bowel syndrome. In particular, the present invention provides compositions and methods for determining polymorphisms associated with ibs-d and crohn's disease.
The Regents Of The University Of Michigan
Conjugates of a phospholipid and a drug for the treatment of inflammatory bowel disease
Conjugates of drugs suitable for use in the treatment of inflammatory bowel disease and phospholipids, and their use in the treatment of inflammatory bowel disease, are disclosed. The disclosed conjugates serve as targeted prodrugs which are suitable for oral administration, and which are capable of releasing the drug selectively at the diseased tissue upon activation by pla2..
Ben-gurion University Of The Negev Research And Development Authority
Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof
These compounds are useful in the treatment, prevention, prophylaxis, management, or adjunct treatment of all medical conditions related to inhibition of bruton's tyrosine kinase (btk), such as inflammatory and/or autoimmune disorder, cell proliferation, rheumatoid arthritis, psoriasis, psoriatic arthritis, transplant rejection, graft-versus-host disease, multiple sclerosis, inflammatory bowel disease, allergic diseases, asthma, type 1 diabetes, myasthenia gravis, hematopoetic disfunction, b-cell malignancies, systemic lupus, erythematosus or other disorders.. .
Therapeutic uses of humanized antibodies against alpha-4 integrin
The invention provides methods of treatment using humanized immunoglobulins that specifically bind to alpha-4 integrin. The methods are useful for treatment of asthma, atherosclerosis, aids dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, transplant rejection, graft versus host disease, tumor metastasis, nephritis, atopic dermatitis, psoriasis, myocardial ischemia, and acute leukocyte mediated lung injury..
Biogen Idec Ma Inc.
4-oxo-2-pentenoic acid and the health of the digestive tract
The present invention relates generally to compositions with a health benefit. In particular, the invention relates to the field of inflammatory disorders of the digestive tract, for example, ileitis, colitis, rectal inflammation, pharyngitis, leaky gut syndrome, irritable bowel syndrome and inflammatory bowel disease.
Methods for treating inflammatory diseases with compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof
There are provided methods for treating an inflammatory diseases chosen from inflammatory bowel diseases, asthma, acute respiratory distress syndrome, chronic obstructive pulmonary disease, acute lung injury, bronchopulmonary dysplasia, cystic fibrosis, bronchitis, bronchiolitis, arthritis, osteoarthritis, ankylosing spondylitis and rheumatism. The method comprise administering to a subject in need thereof an effective amount of at least one lipid and an effective amount of at least one compound chosen from compounds of the present disclosure.
Scf Pharma Inc.
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
The invention provides novel guanylate cyclase-c agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cgmp-dependent phosphodiesterase.
Synergy Pharmaceuticals, Inc.
Method, composition and package for bowel cleansing
The present invention provides a highly palatable colon cleansing formulation that utilizes a low chloride electrolyte-replenishing base solution. When formulated with polyethylene glycol and a selected sugar alcohol, the formulation offers the advantages of superior palatability without undesirable concomitant side effects or a decrease in cleansing efficacy..
Braintree Laboratories, Inc.
Controlled-release solid dosage forms of mesalamine
Described are controlled-release solid dosage forms of mesalamine. In one aspect of the invention the controlled-release solid dosage forms of mesalamine are capsules comprising a plurality of coated mini-tablets.
Steroid sparing agents and methods of using same
This invention relates generally to methods of treating inflammatory bowel diseases (ibd), asthma, crohn's disease (cd), multiple sclerosis (ms), rheumatoid arthritis (ra), graft versus host disease (gvhd), host versus graft disease, and various spondyloarthropathies, comprising administering a steroid-sparing effective amount of an immunoglobulin or small molecule composition to a patient in need thereof. The invention also relates generally to combination therapies for the treatment of these conditions..
Biogen Idec Ma Inc.
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Bowel topics: Bowel Disease, Inflammatory Bowel Disease, Irritable Bowel Syndrome, Inflammation, Mercaptopurine, Probiotics, Abdominal Pain, Discomfort, Bowel Movement, Gastrointestinal, Ulcerative Colitis, Rheumatoid Arthritis, Jejunal Tube, Spring Mechanism, Small Bowel
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