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Bowel patents



      
           
This page is updated frequently with new Bowel-related patent applications. Subscribe to the Bowel RSS feed to automatically get the update: related Bowel RSS feeds. RSS updates for this page: Bowel RSS RSS


Date/App# patent app List of recent Bowel-related patents
04/30/15
20150119467
 Methods for treatment of pelvic pain and/or comorbid conditions patent thumbnailnew patent Methods for treatment of pelvic pain and/or comorbid conditions
Methods, systems, devices, and medicaments are provided for locally administering to a pelvic-area organ or tissue structure in a patient at least one drug continuously or continually over a treatment period of 24 hours or more in an amount effective to achieve a therapeutic effect in another organ or tissue structure by means of shared or convergent pelvic afferent pathways. The methods systems, devices, and medicaments can be used in the treatment of ic/bps, chronic pelvic pain, vulvodynia, orchialgia, urethral syndrome, dysparenia, chronic prostatitis, chronic pelvic pain, levator ani syndrome, irritative bowel syndrome, or a combination thereof.
Allergan, Inc.
04/30/15
20150119344
 Compositions and methods for the treatment of cardiovascular and neurological diseases patent thumbnailnew patent Compositions and methods for the treatment of cardiovascular and neurological diseases
The invention relates to the compounds of formula i, formula ii and formula iii or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i, formula ii or formula iii and methods for the treatment of cardiovascular and neurological diseases may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection.
04/30/15
20150119321
 System and  losing weight patent thumbnailnew patent System and losing weight
A unique combination of weight loss modalities that produce 20-40 pounds of weigh loss in a six week treatment period. Treatment includes a meal plan chosen to provide adequate protein and nutrition during dieting and to assist metabolism of toxins created from the release of stored fat, high amounts of fiber to assist in collecting toxins and fat in the elimination system and to encourage peristaltic action in the bowel, a bowel toner to further increase peristaltic action in the bowel, stimulating liver functions of fat and toxins.
04/30/15
20150118296
 Controlled release budesonide compositions patent thumbnailnew patent Controlled release budesonide compositions
The present invention relates to controlled release pharmaceutical compositions comprising budesonide. The invention also relates to processes for the preparation of such compositions and using those compositions in the treatment of inflammatory bowel disease and irritable bowel syndrome including mild to moderate ulcerative colitis..
Cadila Healthcare Limited
04/30/15
20150118217
 Treatment of disease conditions via administration of dna repair enzyme patent thumbnailnew patent Treatment of disease conditions via administration of dna repair enzyme
The present invention is directed to compositions and methods of preserving viability of islets of langerhans for transplantation, and treating various disease and other abnormal or pathological conditions, including inflammatory bowel disease, ischemic heart disease, acute lung injury, acute respiratory distress syndrome and radiation-induced brain injury, with dna repair enzymes that are directed to the mitochondria.. .
University Of South Alabama
04/23/15
20150111937
 Compositions and methods for treating intestinal hyperpermeability patent thumbnailCompositions and methods for treating intestinal hyperpermeability
The present invention provides methods, compositions, and kits for treating intestinal hyperpermeability in a subject in need thereof, including conditions such as hyperglycemia and underlying diseases such as diabetes, autism, fibromyalgia, inflammatory bowel disease (ibd), graft versus host disease (gvhd), hiv/aids, multiple organ dysfunction syndrome, irritable bowel syndrome (ibs), celiac disease, eczema, psoriasis, acute pancreatitis, parkinson's disease, depression, chronic fatigue syndrome, asthma, multiple sclerosis, arthritis, ankylosing spondylitis, nonalcoholic fatty liver disease, alcoholic cirrhosis, environmental enteropathy, or kwashiorkor.. .
04/23/15
20150111878
 Compositions and methods for treating intestinal hyperpermeability patent thumbnailCompositions and methods for treating intestinal hyperpermeability
The present invention provides methods, compositions, and kits for treating intestinal hyperpermeability in a subject in need thereof, including underlying diseases such as diabetes, autism, fibromyalgia, inflammatory bowel disease (ibd), graft versus host disease (gvhd), hiv/aids, multiple organ dysfunction syndrome, irritable bowel syndrome (ibs), celiac disease, eczema, psoriasis, acute pancreatitis, parkinson's disease, depression, chronic fatigue syndrome, asthma, multiple sclerosis, arthritis, ankylosing spondylitis, nonalcoholic fatty liver disease, alcoholic cirrhosis, environmental enteropathy, or kwashiorkor.. .
04/23/15
20150111865
 Trk-inhibiting compound patent thumbnailTrk-inhibiting compound
(wherein all symbols represent the same meanings as described in the specification), a salt thereof, an n-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or chagas disease.. .
04/23/15
20150110838
 Compositions and methods for treating crohn's disease and related conditions and infections patent thumbnailCompositions and methods for treating crohn's disease and related conditions and infections
In alternative embodiments, the invention provides a “triple combination” therapy for treating, ameliorating and preventing crohn's disease (or crohn syndrome, terminal or distal ileitis or regional enteritis) or related disorders and conditions in mammals, such as paratuberculosis in mammals, or johne's disease, including genetically-predisposed and chronic disorders, where the microbial or bacterial flora of the bowel is at least one causative or symptom-producing factor; and compositions for practicing same. In alternative embodiments, methods and compositions of the invention comprise or comprise use of therapies, medications, formulations and pharmaceuticals comprising active agents that can suppress or eradicate the microbiota super-infection that causes crohn's disease or paratuberculosis infection in mammals.
04/23/15
20150110834
 Fungal mycobiome as probiotics, diagnostics and therapeutics patent thumbnailFungal mycobiome as probiotics, diagnostics and therapeutics
The present invention relates to methods of using fungal mycobiome as a means of treating and/or diagnosing diseases in a subject. In one embodiment, the present invention provides a method of diagnosing inflammatory bowel disease based on the composition of fungal strains present in the gut of a subject, and treating the subject by administering a probiotic biotherapy.
Cedars-sinai Medical Center
04/23/15
20150110718

Methods and kits for determining a placebo profile in subjects for clinical trials and for treatment of patients


The present invention is directed to methods and assays for identifying subjects participating in clinical trials that may exhibit a placebo response and identifying treatments for subjects with varying degrees of placebo responses. In one aspect, a method of selecting subjects to participate in a clinical trial is disclosed.
Biometheus Llc
04/16/15
20150105356

Materials and methods for treatment and diagnosis of disorders associated with oxidative stress


The subject invention pertains to materials and methods for the prevention and treatment of disease conditions associated with oxidative stress or a compromised reducing environment, including inflammatory bowel diseases such as crohn's disease and ulcerative colitis. Another aspect of the subject invention concerns compositions formulated for administration as an enema.
Therapeutic Research Llc
04/16/15
20150105337

Enterobactin conjugates and uses thereof


The present invention provides novel enterobactin-cargo conjugates, such as compounds of formula (i), and salts thereof, where x is the cargo and may be an antibiotic, a fluorophore, or biotin. The present invention also provides complexes, compositions, kits, and methods that involve the compounds of formula (i) and are useful in delivering a cargo to a bacterium, treating a bacterial infection, cystic fibrosis, and/or inflammatory bowel disease in a subject, preventing a bacterial infection, cystic fibrosis, and/or inflammatory bowel disease in a subject, inhibiting the growth of or killing a bacterium, or determining the concentration of a bacterium in a biological sample.
Massachusetts Institute Of Technology
04/09/15
20150099762

Compounds as rearranged during transfection (ret) inhibitors


This invention relates to novel compounds which are inhibitors of the rearranged during transfection (ret) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to ret dysfunction or where modulation of ret activity may have therapeutic benefit including but not limited to all classifications of irritable bowel syndrome (ibs) including diarrhea-predominant, constipation-predominant or alternating stool pattern, functional bloating, functional constipation, functional diarrhea, unspecified functional bowel disorder, functional abdominal pain syndrome, chronic idiopathic constipation, functional esophageal disorders, functional gastroduodenal disorders, functional anorectal pain, inflammatory bowel disease, proliferative diseases such as non-small cell lung cancer, hepatocellular carcinoma, colorectal cancer, medullary thyroid cancer, follicular thyroid cancer, anaplastic thyroid cancer, papillary thyroid cancer, brain tumors, peritoneal cavity cancer, solid tumors, other lung cancer, head and neck cancer, gliomas, neuroblastomas, von hippel-lindau syndrome and kidney tumors, breast cancer, fallopian tube cancer, ovarian cancer, transitional cell cancer, prostate cancer, cancer of the esophagus and gastroesophageal junction, biliary cancer, adenocarcinoma, and any malignancy with increased ret kinase activity.. .
Glaxosmithkline Intellectual Property Development Limited
04/09/15
20150099713

Method of treating constipation-predominant irritable bowel syndrome


Disclosed is a method of manipulating the rate of gastrointestinal transit in a mammalian subject. Also disclosed is the use, in the manufactiurc of a medicament for the treatment of constipation, of a selective inhibitor of methanogensis, a methanogen-displacing probiotic agent, or a prebiotic agent that inhibits the growth of methanogenic bacteria or promotes the growth of competing non-methanogenic intestinal flora.
Cedars-sinai Medical Center
04/02/15
20150094272

Treatments for gastrointestinal disorders


The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (ibs), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (gerd), duodenogastric reflux, crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein, using peptides and other agents that activate the guanylate cyclase c (gc-c) receptor.. .
Ironwood Pharmaceuticals, Inc.
04/02/15
20150094265

Treatments for gastrointestinal disorders


The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (ibs), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (gerd), duodenogastric reflux, crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein. Using peptides and other agents that activate the guanylate cyclase c (gc-c) receptor..
Ironwood Pharmaceuticals, Inc.
03/26/15
20150086567

Role of ifng methylation in inflammatory bowel disease


The invention relates to method of diagnosing susceptibility to inflammatory bowel disease (ibd) in an individual by obtaining a sample from the individual, assaying the sample to determine the presence or absence of one or more risk genetic variants and/or an increase in ifng dna methylation. In one embodiment, the present invention provides a method of diagnosing susceptibility to inflammatory bowel disease (ibd) in an individual by obtaining a sample from the individual, assaying the sample to determine the presence or absence of one or more risk genetic variants and/or an increase in ifng dna methylation relative to a normal subject, and diagnosing susceptibility to inflammatory bowel disease based on the presence of one or more risk genetic variants and/or an increase in ifng dna methylation relative to a normal subject.
Cedars-sinai Medical Center
03/19/15
20150080861

Sponge sheath for laparoscopic aspirator


The present invention relates to the aspirators, one of the hand tools used in laparoscopic surgery. In the present invention, a sponge sheath that can be fitted on the known aspirator tip structure in order to prevent blockage that may occur in the aspirators by adherence of the bowel and omentum during the aspiration of the interior of the abdomen..
03/19/15
20150080377

Deuterium-enriched pyridinonecarboxamides and derivatives


Are partial or full agonists of serotonin (5-hydroxytryptamine or 5-ht) receptor subtype 4 (5-ht4), and are useful compounds for the prevention and treatment of alzheimer's disease, cognitive and memory dysfunction, mild cognition impairment, memory decline, cognitive impairment associated with schizophrenia, cognitive impairment associated with age-related dementia or alzheimer's disease, cognitive impairment associated with post-coronary bypass surgery, attention deficit hyperactivity disorder, obsessive compulsive disorder, depression, speech improvement in autistic children, sleep apnea in alzheimer's patients, age-related macular degeneration (amd), irritable bowel syndrome, gastroesophageal reflux disease, crohn's disease, emesis, nausea, vomiting, prokinesia, non-ulcer dyspepcia, anxiety, depression, pain, migraine, urinary incontinence, arterial fibrillation, arrhythmia, ischemic stroke, gastric emptying disorders, gastritis, gastrointestinal disorders, feeding disorders, obesity, anorexia, constipation, respiratory depression, and erectile dysfunction.. .
03/19/15
20150079128

Chinese medicinal formulation for treating inflammatory bowel disease and the preparation thereof


This invention relates to a chinese medicinal formulation for the treatment of inflammatory bowel diseases, and a method of preparation thereof. The formulation comprises herbal components selected from a group consisting of radix codonopsis (dangshen), rhizoma atractylodis macrocephalae (bai zhu), sclerotium poriae cocos (fu ling), rhizoma zingiberis officinalis (gan jiang), radix paeoniae alba (bai shao) and rhizoma coptidis (huanglian)..
Hong Kong Baptist University
03/12/15
20150073125

Recombinant probiotic bacteria for the prevention and treatment of inflammatory bowel disease (ibd) and irritable bowel syndrome (ibs)


The present invention relates to the general field of therapy of inflammatory bowel disease (ibd) and/or irritable bowel syndrome (ibs). Thus, the invention relates to a molecule selected from the trappin-2 protein or an active fraction thereof, a member of the wap family proteins or an active fraction thereof or a member of the serpin family proteins or an active fraction thereof for the treatment of irritable bowel syndrome (ibs).
Universite Paris Diderot - Paris 7
03/12/15
20150072962

Novel cholesterol metabolite, 5-cholesten, 3beta-25-diol, disulfate (25hcds) for therapy of metabolic disorders, hyperlipidemia, diabetes, fatty livers diseases and atherosclerosis


5-cholesten, 3β, 25-diol, disulfate (25hcds) has been found to be an authentic pparγ agonist and lxr antagonist, and is used for the therapy of lipid disorders and inflammatory diseases, including without limitation fatty liver, inflammatory bowel, and atherosclerotic diseases.. .
Virgini Commonwealth University
03/12/15
20150072879

Methods for improving inflammatory bowel disease diagnosis


The present invention provides methods and systems to predict and diagnose inflammatory bowel disease (ibd) and subtypes such as ulcerative colitis (uc) and crohn's disease (cd) by detecting the presence, absence, level, and/or genotype of one or more sero-genetic-inflammation markers. Advantageously, with the present invention, it is possible to provide a diagnosis of ibd versus non-ibd, to rule out ibd that is inconclusive for cd and uc, and to differentiate between cd and uc with increased accuracy..
Nestec S.a.
03/12/15
20150072014

Pharmaceutical compositions of sodium picosulfate, magnesium oxide and citric acid


The present invention relates to pharmaceutical compositions of sodium picosulfate, magnesium oxide and citric acid. In particular, the invention relates to pharmaceutical compositions comprise granules having a layer of sodium picosulfate on neutral carrier/s.
Cadila Healthcare Limited
03/05/15
20150065995

Intraluminal occluding catheter


An intraluminal occluding catheter and method for preventing the loss of gas insufflation from a physiological lumen during a medical procedure is presented. The intraluminal occluding catheter is generally comprised of a catheter shaft having a flexible balloon affixed on a distal intraluminal end and a plurality of independent channels extending through the catheter shaft from the external proximal end to the distal intraluminal end.
University Of South Florida
03/05/15
20150065566

Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer


The present invention provides methods for preventing colon cancer by administering, to a patient in need thereof, a polymeric proanthocyanidin composition from a croton species or calophyllum species in an amount sufficient to prevent colon cancer, which composition inhibits cox-2. The present invention also provides methods for treating inflammation locally in the intestines comprising administering to a patient in need thereof, a polymeric proanthocyanidin composition from a croton species or calophyllum species in an amount sufficient to treat inflammation.
03/05/15
20150065530

Biomarker associated with irritable bowel syndrome and crohn's disease


The present invention provides compositions and methods for characterizing irritable bowel syndrome. In particular, the present invention provides compositions and methods for determining polymorphisms associated with ibs-d and crohn's disease.
The Regents Of The University Of Michigan
03/05/15
20150065462

Conjugates of a phospholipid and a drug for the treatment of inflammatory bowel disease


Conjugates of drugs suitable for use in the treatment of inflammatory bowel disease and phospholipids, and their use in the treatment of inflammatory bowel disease, are disclosed. The disclosed conjugates serve as targeted prodrugs which are suitable for oral administration, and which are capable of releasing the drug selectively at the diseased tissue upon activation by pla2..
Ben-gurion University Of The Negev Research And Development Authority


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Bowel topics: Bowel Disease, Inflammatory Bowel Disease, Irritable Bowel Syndrome, Inflammation, Mercaptopurine, Probiotics, Abdominal Pain, Discomfort, Bowel Movement, Gastrointestinal, Ulcerative Colitis, Rheumatoid Arthritis, Jejunal Tube, Spring Mechanism, Small Bowel

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