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Bowel-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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3-(6-alkoxy-5-chlorobenzo[d]isoxazol-3-yl)propanoic acid useful as kynurenine monooxygenase inhibitors
December 07, 2017 - N°20170349577

And salts thereof are kmo inhibitors and may be useful in the treatment of various disorders, for example acute pancreatitis, chronic kidney disease, acute kidney disease, acute kidney injury, other conditions associated with systemic inflammatory response syndrome (sirs), huntington's disease, alzheimer's disease, spinocerebellar ataxias, parkinson's disease, aids-dementia complex, hiv infection, amylotrophic lateral sclerosis (als), depression, schizophrenia, sepsis, cardiovascular shock, severe ...
5-ht2b antagonists
December 07, 2017 - N°20170349559

And related methods for treating a person having a disorder characterized by undesirable 5-ht2b receptor signaling, such as migraine, irritable bowel syndrome (ibs), pulmonary arterial hypertension (pah), fibrosis, hepatocellular cancer, a small intestinal neuroendocrine tumor, cardiovascular disorders, and gastrointestinal (gi) tract disorders.
N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and ...
Pimco 2664 Limited
December 07, 2017 - N°20170349551

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted n-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamide compounds (collectively referred to herein as hmc compounds) that are useful, for example, in the treatment of disorders (e. G., diseases) including, inflammation and/or joint destruction ...
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Compositions containing omega-3 oil and uses thereof
Maine Natural Health Company, Inc.
December 07, 2017 - N°20170348272

The invention provides pharmaceutical compositions containing omega-3 oil and a non-hydrophilic co-solvent that have an increased absorption rate. The pharmaceutical compositions may further contain one or more pharmaceutical organic molecules. The invention further provides kits containing these pharmaceutical compositions, methods for formulating pharmaceutical compositions containing omega-3 oil, and methods for decreasing the likelihood of developing cardiovascular disease, decreasing triglyceride or ...
Calcifediol soft capsules
Faes Farma, S.a.
December 07, 2017 - N°20170348249

The present invention relates to calcifediol soft capsules, to their use in the treatment or prevention of diseases related to vitamin d deficiency, such as vitamin d deficiency, demineralization such as hypocalcemia and hypophosphatemia, renal osteodystrophy, rickets, osteoporosis, osteopenia, osteoarthritis, osteoarthrosis, osteomalacia, hypoparathyroidism, and inflammatory bowel disease, and to their process of manufacture.
A system and a method for anal and/or stomal irrigation
Coloplast A/s
December 07, 2017 - N°20170348138

A system for anal and/or stomal irrigation of a user's bowel comprises a reservoir (102) for an irrigating liquid, a catheter (100) for insertion into the rectum and/or stoma of a user and for expelling of the irrigating liquid from a catheter tip, and an expandable retention element (104), such as a balloon, for fixation of the catheter tip within the ...
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  • 226+ full patent PDF documents of Bowel-related inventions.
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Sik inhibitor for use in a method of treating an inflammatory and/or immune disorder
University Court Of The University Of Dundee
November 30, 2017 - N°20170342036

The present invention relates to the discovery that salt inducible kinases (siks) suppress the formation of anti-inflammatory molecules such as il-10, which are important for the resolution of inflammation and identifies sik inhibitors that may be used to treat disorders associated with undesirable inflammation, such as inflammatory bowel disease and/or autoimmune disorders.
Msi-specific frameshift peptides (fsp) for prevention and treatment of cancer
Ruprecht-karls-universität Heidelberg
November 30, 2017 - N°20170340717

Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (msi). The vaccine contains an msi-specific frameshift peptide (fsp) generating humoral and cellular responses against tumor cells or a nucleic acid encoding said fsp. The vaccine of the present invention is particularly useful for the prevention/treatment of colorectal cancer, endometrial cancer, gastric cancer or small ...
Trk-inhibiting compound
Ono Pharmaceutical Co., Ltd.
November 30, 2017 - N°20170340634

The present invention provides a drug containing a compound having trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or chagas disease. A compound represented by the general formula (i), wherein all symbols represent the same meanings as described in the ...
Sulfonyl piperidine derivatives and their use for treating prokineticin mediated gastrointestinal disorders
Takeda Pharmaceutical Company Limited
November 30, 2017 - N°20170340621

The present invention provides compounds of formula (i) and pharmaceutically acceptable salts thereof (formula (i)) in which m, n, w, x, y, z, r1, r2, r3, r4 and r5 are as defined in the specification for use in treating irritable bowel syndrome or inflammatory bowel disease.
Pyridone derivatives as rearranged during transfection (ret) kinase inhibitors
Glaxosmithkline Intellectual Property Development Limited
November 30, 2017 - N°20170340617

This invention relates to novel compounds which are inhibitors of the rearranged during transfection (ret) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to ...
Method for detecting methylation of colorectal cancer specific methylation marker gene for colorectal cancer diagnosis
Genomictree, Inc.
November 23, 2017 - N°20170335407

The present disclosure relates to a method for detecting methylation of the bowel-cancer-specific methylation marker gpm6a (nm_201591, glycoprotein m6a) gene in order to diagnose bowel cancer, and more specifically relates to a method for providing information for diagnosing bowel cancer by detecting the methylation of a bowel-cancer-specific marker gene that is specifically methylated in bowel cancer cells. The ...
Chimeric compounds targeting proteins, compositions, methods, and uses thereof
Biotheryx, Inc.
November 23, 2017 - N°20170334932

The present invention provides chimeric compounds that modulate protein function, to restore protein homeostasis, including cytokine, aiolos, and/or ikaros activity, tnf-alpha activity, ck1-alpha activity and cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, ...
Bowel Patent Pack
Download 226+ patent application PDFs
Bowel Patent Applications
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For professional research & prior art discovery
inventor
  • 226+ full patent PDF documents of Bowel-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Probiotic fermented cereal compositions and methods for treatment of gastrointestinal diseases caused by pro-inflammatory bacteria
Nordisk Rebalance A/s
November 23, 2017 - N°20170333514

The invention covers a novel treatment strategy that considerably improves conventional probiotic treatments of inflammatory bowel diseases, irritable bowel syndrome and other gastrointestinal disorders. Both probiotic microorganisms and the carrier of the probiotic microorganisms in form of a fermented cereal gruel are used as treatment effectors. Phospholipids may also be an effecter. The novel treatment strategy is capable of removing ...
Prevention, treatment, and amelioration of radiation induced enteritis
Nordisk Rebalance A/s
November 23, 2017 - N°20170333458

The present invention provides a new method of ameliorating and/or treating enteritis induced by radiation therapy, alone or in combination with other therapies, for the treatment oil for example, gastrointestinal malignancies, including colorectal, appendiceal, anal, or small bowel cancers; urogenital malignancies, including prostate, bladder, testicular, or penile cancers; gynecologic malignancies, including cervical, endometrial, ovarian, vaginal, or vulvar cancers; or ...
Chimeric compounds targeting proteins, compositions, methods, and uses thereof
Biotheryx, Inc.
November 23, 2017 - N°20170333443

The present invention provides chimeric compounds that modulate protein function, to restore protein homeostasis, including cytokine, aiolos, and/or ikaros activity, tnf-alpha activity, ck1-alpha activity and cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, ...
Novel anti-inflammatory agents
Resverlogix Corp.
November 23, 2017 - N°20170333419

Disclosed are methods of regulating interleukin-6 (il-6) and/or vascular cell adhesion molecule-1 (vcam-1) and methods of treating and/or preventing cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s) by administering a naturally occurring or synthetic quinazolone derivative. The invention provides ...
Gold kiwifruit compositions and methods of preparation and use therefor
Anagenix Ip Limited
November 16, 2017 - N°20170326190

The present disclosure encompasses compositions prepared from kiwifruit. In particular, the invention encompasses compositions prepared from gold varieties of actinidia chinensis. Also encompassed are methods of preparing these compositions. Further encompassed are methods of using these compositions, in particular, for treating or preventing disorders of the gastrointestinal system, including amongst others: inflammation, constipation, bowel irregularity, microbiota imbalances, irritable bowel syndrome, ...
Novel anti-inflammatory agents
Resveriogix Corp.
November 16, 2017 - N°20170326143

Disclosed are methods of regulating interleukin-6 (il-6) and/or vascular cell adhesion molecule-1 (vcam-1) and methods of treating and/or preventing cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s) by administering a naturally occurring or synthetic quinazolone derivative. The invention provides ...
Methods for distinguishing inflammatory bowel diseases using microbial community signatures
Resveriogix Corp.
November 09, 2017 - N°20170321256

The inventive subject matter relates broadly to novel techniques for identification and comparative analysis of sequence features in metagenomic whole-genome shotgun (wgs) sequence data associated with particular disease states in a subject. More particularly, the inventive subject matter relates to diagnostic methods for distinguishing between different types of inflammatory bowel disease in a subject based on the microbial community signature ...
Selective termination of stimulation to deliver post-stimulation therapeutic effect
Medtronic, Inc.
November 09, 2017 - N°20170319849

In some examples, electrical stimulation is delivered to a patient such that selective termination of the stimulation causes a therapeutic effect in the patient after termination of the electrical stimulation to the patient. The electrical stimulation may be insufficient to produce a desired therapeutic effect in the patient during stimulation, but sufficient to induce a post-stimulation desired therapeutic effect following ...
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