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Bowel patents



      
           
This page is updated frequently with new Bowel-related patent applications. Subscribe to the Bowel RSS feed to automatically get the update: related Bowel RSS feeds. RSS updates for this page: Bowel RSS RSS


Date/App# patent app List of recent Bowel-related patents
07/10/14
20140194698
 Abdominal retractor patent thumbnailAbdominal retractor
Devices and methods for retracting tissue, such as bowels and organs, within the body of a patient are generally disclosed. In particular, the present disclosure describes surgical retractors having a series of intersecting strands defining openings there between, wherein the openings are enlargeable by slidable passage of the strands relative to one another.
07/10/14
20140193408
 Soluble proteins for use as therapeutics patent thumbnailSoluble proteins for use as therapeutics
The present invention relates to improved binding proteins, for use as a medicament, in particular for the prevention or treatment of autoimmune and inflammatory disorders, for example allergic asthma and inflammatory bowel diseases. The invention more specifically relates to a soluble protein, comprising a complex of two heterodimers, wherein each heterodimer essentially consists of: (i) a first single chain polypeptide comprising: (a) an antibody heavy chain sequence having vh, ch1, ch2, and ch3 regions; and (b) a monovalent region of a mammalian binding molecule fused to the vh region; and (ii) a second single chain polypeptide comprising: (c) an antibody light chain sequence having a vl and cl region; and (d) a monovalent region of a mammalian binding molecule fused to the vl region; characterised in that each pair of vh and vl cdr sequences has specificity for an antigen, such that the total valency of said soluble protein is six.
07/10/14
20140193388
 Modified phosphatases patent thumbnailModified phosphatases
The invention relates to phosphatases and more in specific to (genetically) modified phosphatases, pharmaceutical compositions comprising (genetically) modified phosphatases and the use of (genetically) modified phosphatases for treating or curing for example sepsis, inflammatory bowel disease or other inflammatory diseases, or renal failure. The invention further relates to a method for producing phosphatases..
07/10/14
20140193332
 Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders patent thumbnailCompositions and methods for the diagnosis and treatment of inflammatory bowel disorders
The present invention is directed to compositions of matter useful for the diagnosis and treatment of inflammatory bowel diseases in mammals and to methods of using those compositions of matter for the same.. .
07/03/14
20140187859
 Endoluminal introducer patent thumbnailEndoluminal introducer
An introducer for use during endoscopic procedures provides insufflation, washing, and aspiration functions, and provides for the protection of the endoluminal surface during laparoscopic examination of an anastomosis or suture line following low anterior resection of the bowel. The introducer may be designed for the insertion of an endoscope capable of white light and/or near infra-red fluorescence imaging into the rectum for analysis of an anastomosis following low anterior resection of the bowel..
07/03/14
20140187602
 Anti-sense oligonucleotides targeted against exon 9 of il-23r alpha gene and method of using same to induce exon skipping and to treat inflammatory bowel diseases patent thumbnailAnti-sense oligonucleotides targeted against exon 9 of il-23r alpha gene and method of using same to induce exon skipping and to treat inflammatory bowel diseases
The present invention relates to anti-sense oligonucleotides (aons) used to induce exon 9 skipping in il-23rαgene. Exon 9 skipping of the il23rα gene ultimately causes specific induction of a novel soluble truncated il-23rα (Δ9) protein, characterized by a lack in a transmembrane domain and has a unique eight (8) amino acids (glkegsyc) at its c-terminus end as a result of frame-shift.
07/03/14
20140187579
 Tip60 inhibitors patent thumbnailTip60 inhibitors
This invention is in the fields of immunology and autoimmunity. More particularly it concerns pharmaceutical compositions comprising compounds which are useful agents for inhibiting the functions of tip60 and the use of such compounds in the treatment of an individual suffering, for example, from ulcerative colitis and other irritable bowel diseases..
07/03/14
20140187521
 Amelioration of intestinal fibrosis and treatment of crohn's disease patent thumbnailAmelioration of intestinal fibrosis and treatment of crohn's disease
Methods of treating patients with inflammatory bowel disease, intestinal fibrosis, or crohn's disease involve administering a therapeutic amount of card-024 or related compound.. .
07/03/14
20140187517
 Method for treating intestinal diseases presenting at least one inflammatory component patent thumbnailMethod for treating intestinal diseases presenting at least one inflammatory component
The present disclosure relates to methods for treating intestinal diseases presenting at least one inflammatory component such as inflammatory bowel disease or diverticular disease and/or maintaining remission of intestinal diseases presenting at least one inflammatory component such as inflammatory bowel disease (ibd) or diverticular disease using budesonide mmx compositions.. .
07/03/14
20140187490
 Val (8) glp-1 composition and method for treating functional dyspepsia and/or irritable bowel syndrome patent thumbnailVal (8) glp-1 composition and method for treating functional dyspepsia and/or irritable bowel syndrome
A method of treating functional dyspepsia and/or irritable bowel syndrome in mammals in need of treatment is disclosed herein. The method comprises administering to the mammal a formulation by inhalation, wherein the formulation avoids first pass metabolism of the active ingredient.
07/03/14
20140186450
Gastroresistant pharmaceutical formulations containing rifaximin
The object of the invention consists of pharmaceutical formulations containing rifaximin in the shape of microgranules made gastroresistant by an insoluble polymer at ph values between 1.5 and 4.0 and soluble at ph values between 5.0 and 7.5, by their preparation and by their use in the manufacture of medicinal preparations useful in the treatment of inflammatory bowel diseases (ibd) and mainly crohn's disease.. .
06/26/14
20140179693
Methods for treating vascular leak syndrome
Disclosed are methods for treating vascular leak syndrome. Further disclosed are methods for treating vascular leakage due to inflammatory diseases, inter alia, sepsis, lupus, inflammatory bowel disease.
06/26/14
20140179620
Gene expression markers for inflammatory bowel disease
The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more ibd markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an ibd in the mammalian subject from which the test sample was obtained.. .
06/26/14
20140179549
Methods for identifying inflammatory bowel disease patients with dysplasia or cancer
The present invention provides methods for identifying ibd patients with dysplasia or cancer. In particular embodiments, the methods of the invention may comprise determining the presence or level of at least one or a panel of mirnas in a sample obtained from an ibd patient to establish a mirna expression profile, and comparing the mirna expression profile with one or more pre-established model mirna expression profiles.
06/26/14
20140179537
Compositions and methods for diagnosing colon disorders
The present invention relates to methods and compositions for diagnosing, monitoring, prognosticating, analyzing, etc., polymicrobial diseases. The present invention also relates to the microbial community present in the digestive tract and lumen in normal subjects, and subjects with digestive tract diseases, especially diseases of the colon, such as inflammatory bowel disease, including ulcerative colitis, crohn's syndrome, and pouchitis.
06/26/14
20140178492
Bowel cleansing composition
The invention provides compositions for rapid bowel cleansing comprising a water-soluble mixture of polyethylene glycol and sodium phosphate(s). The compositions are particularly useful for preparing the bowel prior to surgery or diagnostic procedures such as colonoscopies.
06/26/14
20140178404
Use of neuregulin-4 for treatment of inflammatory bowel disease and necrotizing enterocolitis
The invention provides methods, pharmaceutical compositions and kits for treating, inhibiting and/or reducing the severity of inflammatory bowel disease and necrotizing enterocolitis in a subject in need thereof by administering an effective amount of a composition comprising an activator of erbb4.. .
06/26/14
20140175018
Diagnosing and treating inflammatory diseases
A method of diagnosing, monitoring progression of, or monitoring treatment of inflammatory bowel disease comprises determining the levels of cd14+hla-drhi monocytes or monocytes expressing ccr7 or ccr9 or both ccr7 and ccr9 in a sample obtained from a subject, wherein high levels of cd14+hla-drhi monocytes or monocytes expressing ccr7 or ccr9 or both ccr7 and ccr9, or increased levels of cd14+hla-drhi monocytes or monocytes expressing ccr7 or ccr9 or both ccr7 and ccr9 compared to control, indicate the presence or progression of inflammatory bowel disease. Similar methods for diagnosing irritable bowel syndrome are also described.
06/19/14
20140170178
Msi-specific frameshift peptides (fsp) for prevention and treatment of cancer
Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (msi). The vaccine contains an msi-specific frameshift peptide (fsp) generating humoral and cellular responses against tumor cells or a nucleic acid encoding said fsp.
06/19/14
20140170173
Method of inducing immune tolerance comprising administering carbonic anhydrase i
The purpose of the present invention is to provide a method for treating autoimmune diseases. Disclosed is a method or the like for the treatment of autoimmune diseases, which utilizes an antigen-specific tolerogenic antigen presenting cell.
06/12/14
20140162963
Treatment of constipation-predominant irritable bowel syndrome
The invention provides methods for treating a patient with constipation-predominant irritable bowel syndrome by administering a therapeutically effective dose of linaclotide.. .
06/05/14
20140154275
Gene expression markers for crohn's disease
The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more ibd markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an ibd in the mammalian subject from which the test sample was obtained.. .
06/05/14
20140154214
Selective glucagon-like-peptide-2 (glp-2) analogues
Glp-2 analogues are disclosed which comprise one of more substitutions as compared to h[gly2]glp-2 and which may have the property of an increased small intestine/colon and stomach/colon selectivity. More particularly, preferred glp-2 analogues disclosed herein comprise substitutions at one or more of positions 11, 16, 20, 24 and/or 28 of the wild-type glp-2 sequence, optionally in combination with further substitutions at position 2 and one or more of positions 3, 5, 7, and 10, and/or a deletion of one or more of amino acids 31 to 33 and/or the addition of a n-terminal or c-terminal stabilizing peptide sequence.
05/22/14
20140142163
Antisense oligonucleotides (odn) against smad7 and uses thereof in medical field
The invention relates to antisense oligonucleotidic sequences (odn) against smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as crohn's disease and ulcerative colitis.. .
05/22/14
20140142100
New macrolides and their use
The use of said compounds as medicaments, in particular for the treatment or prevention of inflammatory and allergic diseases, pharmaceutical compositions containing said compounds and to processes for their preparation. The invention relates in particular to macrolide compounds with antiinflammatory activity mediated primarily through inhibition of phosphodiesterase 4 (pde4) which makes them useful for the treatment and/or prevention of inflammatory and allergic diseases such as chronic obstructive pulmonary disease (copd), asthma, rheumatoid arthritis, atopic dermatitis or inflammatory bowel disease or proliferative diseases such as cancer..
05/22/14
20140141990
Performance of a biomarker panel for irritable bowel syndrome
The present invention provides a method of using a panel of serological and genetic biomarkers to distinguish ibs subjects from healthy subjects and/or to differentiate ibs subtypes from each other. The present invention also provides a method of using one or more psychological measures of a subject in conjunction with a panel of serological and/or genetic biomarkers to further aid in diagnosing ibs or discriminating ibs subtypes from each other..
05/22/14
20140141077
Composition for use in treating and preventing inflammation related disorder
The present invention is related to a use for treating and preventing inflammation related disorder of a composition containing a drug and hyaluronic acid (ha) or ha mixture, whereas the ha or the ha mixture as a delivery vehicle can be a formulation including at least two has having different average molecular weights. The composition has been demonstrated to be capable of reducing the therapeutic dose of a drug on the treatment and prevention of inflammation related disorders is acute inflammatory disease, chronic obstructed pulmonary disease, coeliac disease, conjunctivitis, otitis, allergic rhinitis, gingivitis, aphthous ulcer, bronchitis, gastroesophageal reflux disease (gerd), esophagitis, gastritis, enteritis, peptic ulcer, inflammatory bowel disease (ibd), crohn's disease, irritable bowel syndrome (ibs), intestinal inflammation or allergy, urethritis, cystitis, vaginitis, proctitis, eosinophilic gastroenteritis, or rheumatoid arthritis..


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Bowel topics: Bowel Disease, Inflammatory Bowel Disease, Irritable Bowel Syndrome, Inflammation, Mercaptopurine, Probiotics, Abdominal Pain, Discomfort, Bowel Movement, Gastrointestinal, Ulcerative Colitis, Rheumatoid Arthritis, Jejunal Tube, Spring Mechanism, Small Bowel

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This listing is a sample listing of patent applications related to Bowel for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Bowel with additional patents listed. Browse our RSS directory or Search for other possible listings.
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