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This page is updated frequently with new Bowel-related patent applications. Subscribe to the Bowel RSS feed to automatically get the update: related Bowel RSS feeds. RSS updates for this page: Bowel RSS RSS



Date/App# patent app List of recent Bowel-related patents
07/23/15
20150203537 
 Inhibition of gliadin peptides patent thumbnailInhibition of gliadin peptides
Novel compounds and methods for the inhibition of biological barrier permeability and for the inhibition of peptide translocation across biological barriers are identified. Assays for determining modulators of biological barrier permeability and for peptide translocation across biological barriers are provided.
Alba Therapeutics Corporation


07/23/15
20150202238 
 Compositions and  treatment and prophylaxis of inflammatory bowel disease patent thumbnailCompositions and treatment and prophylaxis of inflammatory bowel disease
Methods and compositions for treating inflammatory bowel disease involve the use of targeted antibiotics in combination with probiotic formulations. The probiotics mitigate many of the deleterious side effects associated with antibiotic use and permit the antibiotic to be administered at a higher dose and for a longer duration than would otherwise be possible in the absence of the probiotic.

07/16/15
20150196602 
 Stem cell therapy for crohn's disease and ulcerative colitis patent thumbnailStem cell therapy for crohn's disease and ulcerative colitis
A therapeutic process for treating an inflammatory bowel disease (ibd) using mesenchymal stem cells includes the steps of isolating a plurality of human mesenchymal stem cells from a human patient, introducing the plurality of human mesenchymal stem cells into the human patient, reducing human pro-inflammatory cytokines, wherein the human pro-inflammatory cytokines include il-12 and il-18, and increasing human anti-inflammatory cytokines, wherein the human anti-inflammatory cytokines include il-10 and tgf-beta. The human mesenchymal stem cells are isolated from an umbilical cord blood or from a human adipose tissue.

07/16/15
20150196589 
 Formulations for alteration of biophysical properties of mucosal lining patent thumbnailFormulations for alteration of biophysical properties of mucosal lining
Conductive formulations containing conductive agents, such as salts, ionic surfactants, or other substances that are in an ionized state or easily ionized in an aqueous or organic solvent environment, and methods of use, have been developed. One or more active agents, such as antivirals, antimicrobials, anti-inflammatories, proteins or peptides, may optionally be included with the formulation.
Pulmatrix, Inc.


07/16/15
20150196511 
 Composition comprising metformin as active ingredient for preventing or treating inflammatory bowel disease patent thumbnailComposition comprising metformin as active ingredient for preventing or treating inflammatory bowel disease
The present invention relates to a composition comprising metformin as an active ingredient for preventing or treating inflammatory bowel disease. The metformin compound or the metformin-etanercept (product name: enbrel) composite according to the present invention may have excellent effects of maintaining the thickness of the small intestine and length of the large intestine normal, inhibiting or decreasing the activity of il-17 and tnf-a, and promoting or increasing the activity of ifnr, and therefore can be effectively used as a pharmaceutical composition for preventing or treating autoimmune diseases including inflammatory bowel disease..
Catholic University Industry Academic Cooperation Foundation


07/16/15
20150196353 
 Electrosurgical resection instrument patent thumbnailElectrosurgical resection instrument
An electrosurgical resection instrument for applying to biological tissue radiofrequency electromagnetic energy has a protective hull comprising a shaped piece of dielectric material mounted to cover an underside of an instrument tip of the instrument. The protective hull acts as a shield to protect tissue that may lie under the instrument tip from damage during treatment.
Creo Medical Limited


07/09/15
20150190548 
 Implant and  producing an implant patent thumbnailImplant and producing an implant
The invention relates to an implant derived from intestinal tissue and to an improved method for producing an implant from intestinal tissue. According to the invention, intestinal tissue comprising a tubular segment of intestine with at least part of its associated vasculature intact is processed by: perfusing the vasculature through a vessel thereof with at least one decellularising medium; and separately perfusing the tubular segment of intestine through its lumen with at least one decellularising medium.
Videregen Limited


07/09/15
20150190433 
 Treatment of inflammatory diseases using placental stem cells patent thumbnailTreatment of inflammatory diseases using placental stem cells
Provided herein are methods of treatment of individuals having an immune-related disease, disorder or condition, for example, inflammatory bowel disease, graft-versus-host disease, multiple sclerosis, rheumatoid arthritis, psoriasis, lupus erythematosus, diabetes, mycosis fungoides (alibert-bazin syndrome), or scleroderma using placental stem cells or umbilical cord stem cells.. .
Anthrogenesis Corporation


07/09/15
20150190389 
 Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorder patent thumbnailCompounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorder
Y is selected from the group consisting of a bond, optionally substituted c1-6 alkylene, optionally substituted benzene, pyridinyl, a polyethylene glycol linker and —(ch2)1-6o(ch2)1-6—, and methods of using such compounds for the treatment of irritable bowel syndrome, chronic kidney disease and end-stage renal disease.. .

07/02/15
20150184244 
 Biomarkers for anti-tnf treatment in ulcerative colitis and related disorders patent thumbnailBiomarkers for anti-tnf treatment in ulcerative colitis and related disorders
Methods and kits are provided for the assessment of the suitability of and/or effectiveness of a target therapy for a tnf mediated-related disorder, such as ulcerative colitis, in a subject, which methods and kits evaluate the presence, absence, and/or magnitude of expression of two or more genes up or down regulated in association with anti-tnf responders in inflammatory gastrointestinal disorders, such as ulcerative colitis, with at least two genes including bcl6 (genbank acc. No.
Janssen Biotech, Inc.


07/02/15
20150182575 

Use of phy906 as treatment for inflammatory bowel disease and/or irritable bowel syndrome


The present invention includes a method of using phy906 for treating a bowel disorder including inflammatory bowel disease and irritable bowel syndrome. Particularly, the present invention provides a multiple symptoms treatment for the bowel disorder..
Yale University


06/25/15
20150175546 

Deuterated vercirnon


Or a pharmaceutically acceptable salt thereof, wherein the variables shown in formula i are as defined in the specification. The compound of formula i is useful for the treatment of a disease selected from the group consisting of inflammatory bowel disease (ibd), such as crohn's disease or ulcerative colitis, and celiac disease..

06/25/15
20150174103 

Urea compounds and their use as enzyme inhibitors


Or a pharmaceutically acceptable salt or derivative thereof. The compound may be used in the treatment or prevention of a disorder selected from appetite regulation, obesity, metabolic disorders, cachexia, anorexia, pain, inflammation, neurotoxicity, neurotrauma, stroke, multiple sclerosis, spinal cord injury, parkinson's disease, levodopa-induced dyskinesia, huntington's disease, gilles de la tourette's syndrome, tardive dyskinesia, dystonia, amyotrophic lateral sclerosis, alzheimer's disease, epilepsy, schizophrenia, anxiety, depression, insomnia, nausea, emesis, alcohol disorders, drug addictions such as opiates, nicotine, cocaine, alcohol and psychostimulants, hypertension, circulatory shock, myocardial reperfusion injury, atherosclerosis, asthma, glaucoma, retinopathy, cancer, inflammatory bowel disease, acute and chronic liver disease such as hepatitis and liver cirrhosis, arthritis and osteoporosis..

06/25/15
20150174080 

Nutritional composition for promoting musculoskeletal health in patients with inflammatory bowel disease (ibd)


A nutritional composition for promoting musculoskeletal health in patients with inflammatory bowel disease is disclosed. The nutritional composition comprises casein protein, vitamin k in a ratio of vitamin k1:vitamin k2 being between 3:1 to 1:3 and the vitamin k providing between 3.5-20 μg/100 kcal of the nutritional composition, vitamin d and alpha-linolenic acid.
Nestec S.a.


06/18/15
20150166558 

Gonadotropin releasing hormone receptor antagonists, the preparation thereof and pharmaceutical composition comprising the same


Disclosed are a gonadotropin releasing hormone receptor antagonist and a pharmaceutical composition including the same, which can be useful in preventing or treating a sex hormone-related disease such as endometriosis, amenorrhea, irregular menstruation, uterine myoma, uterine fibroids, polycystic ovarian disease, lupus erythematous, hypertrichosis, precocious puberty, short stature, acne, alopecia, gonadal steroid-dependent neoplasms, gonadotropin-producing pituitary adenoma, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hyperplasia, contraception, and infertility, as well as alzheimer disease.. .
Sk Chemicals Co., Ltd.


06/18/15
20150164993 

Pharmaceutical composition having preventative or treatment effect on inflammatory bowel diseases


The present invention relates to a pharmaceutical composition, which contains a mixture of extracts of stemonae radix, asparagi tuber, scutellariae radix, schisandrae fructus, rehmanniae radix preparata, armeniacae semen, and moutan cortex radicis, for suppressing the occurrence of inflammatory bowel diseases due to cigarette smoke, a method for preventing or treating inflammatory bowel diseases, a method for suppressing the expression of inflammatory cytokines by using the composition, and to a food composition, which contains a mixture of extracts of stemonae radix, asparagi tuber, scutellariae radix, schisandrae fructus, rehmanniae radix preparata, armeniacae semen, and moutan cortex radicis, for preventing or ameliorating inflammatory bowel diseases due to cigarette smoke. The pharmaceutical composition, according to the present invention, contains the mixture of extracts of stemonae radix, asparagi tuber, scutellariae radix, schisandrae fructus, rehmanniae radix preparata, armeniacae semen, and moutan cortex radicis, thereby reducing the level of mmp12 expression that is known to destroy il-1β, tnf-α, il-6 and mcp-1, which are inflammatory cytokines that accompany the inflammatory bowel diseases, elastin, and collagen, and thus can be widely used in developing a safe and effective inflammatory bowel disease treating agent..
University-industry Cooperation Group Of Kyung Hee University


06/18/15
20150164923 

Use of aminosalicylates in diarrhoea-predominent irritable bowel syndrome


A method for the treatment or prophylaxis of non-inflammatory bowel diseases, diarrhoea-predominant irritable bowel syndrome or other non-specific bowel disorder is disclosed comprising administering to a patient in need of such treatment or prophylaxis an effective amount of balsalazide, or a 4-asa or 5-asa compound modified to include a 4-aba side chain, or a salt or a derivative thereof, or a composition comprising balsalazide the modified compound, or a salt or a derivative thereof together with a suitable carrier. Use of balsalazide, a 4-asa or 5-asa compound modified to include a 4-aba side chain, or a salt or derivative thereof, for the manufacture of a medicament for the treatment or prophylaxis of non-inflammatory bowel diseases, diarrhoea-pre-dominant irritable bowel syndrome or other non-specific bowel disorder is also disclosed..
Salix Pharmaceuticals, Ltd


06/18/15
20150164920 

Controlled release formulation comprising mesalamine


The present invention refers to a controlled release pharmaceutical formulation in solid form comprising mesalamine. The invention also contemplates the preparation of the said formulation and its use for the treatment of patients suffering from inflammatory bowel disease (ibd)..
Laboratorios Del Dr. Esteve S.a.


06/18/15
20150164785 

Devices and methods for treating the gastrointestinal system


Devices and methods for less invasively treating the gastrointestinal system, such as the intestinal mucosa of the small bowel. Embodiments described herein may be used to reduce caloric absorption and effectuate weight loss, for example..
Bridgepoint Medical Inc.


06/18/15
20150164121 

Food supplement composition


A dietary supplement for promoting increased vitality, supporting mood, improving heart health, improving immune strength, improving antioxidant balance, protecting against free radical damage, improving bowel function, and enhancing flavonoid intake. The dietary supplement is a combination of cacao, chia seeds, goji berries, and maca root.
Homeland Housewares, Llc


06/04/15
20150152042 

Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity


Chemical syntheses and medical uses of novel inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, for the treatment and/or management of psychotropic disorders, anxiety disorder, generalized anxiety disorder, depression, post-traumatic stress disorder, obsessive-compulsive disorder, panic disorder, hot flashes, senile dementia, migraine, hepatopulmonary syndrome, chronic pain, nociceptive pain, neuropathic pain, painful diabetic retinopathy, bipolar depression, obstructive sleep apnea, psychiatric disorders, premenstrual dysphoric disorder, social phobia, social anxiety disorder, urinary incontinence, anorexia, bulimia nervosa, obesity, ischemia, head injury, calcium overload in brain cells, drug dependence, attention deficit hyperactivity disorder, fibromyalgia, irritable bowel syndrome, and/or premature ejaculation are described.. .
Auspex Pharmaceuticals, Inc.


06/04/15
20150150953 

Pharmaceutical composition adapted for oral administration and the process for its preparation, for the prevention and treatment of irritable bowel syndrome, based on an intestinal motility modifier and a-d-galactosidase


The invention relates to a pharmaceutical formulation or composition in the form of a tablet, coated tablet, capsule or powder tor reconstitution, for use in irritable bowel syndrome, comprising an intestinal motility modifier and enzyme α-d-galactosidase.. .
Posi Visionary Solutions Llp


06/04/15
20150150934 

Pharmaceutical composition having preventative or treatment effect on inflammatory bowel diseases comprising stemonae radix extract


The present invention relates to a pharmaceutical composition, which comprises a stemonae radix extract, for preventing or treating the occurrence of inflammatory bowel diseases due to cigarette smoke, a method for preventing or treating the occurrence of inflammatory bowel diseases using the composition, a method for suppressing the expression of inflammatory cytokines using the composition, and to a food composition, which comprises the stemonae radix extract, for preventing or treating the occurrence of inflammatory bowel diseases due to cigarette smoke. The pharmaceutical composition comprising the stemonae radix extract, according to the present invention, reduces the level of mmp12 expression that is known to destroy il-1β, tnf-α, and il-6, which are inflammatory cytokines that accompany the inflammatory bowel diseases, and elastin and collagen, and can suppress decrease in the number of lactobacilli in the intestine, and thus can be widely used in developing a safe and effective inflammatory bowel diseases treating agent..
University-industry Cooperation Group Of Kyung Hee University


06/04/15
20150150863 

Compositions and methods for treating pelvic pain and other conditions


Methods are provided for treating conditions including chronic pelvic pain, in which there are palpable trigger points of local areas of muscle restriction and spasticity that recreate or refer pain of patients complaints upon palpation, chronic pelvic pain syndrome, pelvic floor myalgia, pelvic floor dysfunction, interstitial cystitis, levator ani syndrome, coccygodynia, prostatodynia, piriformis syndrome, anal sphincter pain, bowel movement pain, post bowel movement pain, ejaculatory pain, post ejaculatory pain, sitting pain, post bowel movement pain, rectal pain, tailbone pain, urinary frequency, urinary urgency, urinary hesitancy, post urinary pain, overactive bladder, perineal pain, penile pain, vaginismus, anismus, sexual dysfunction, reduced level of ejaculate or reduced penile erection, myofascial pain in muscle tissue of a patient who has one or more trigger points in the muscle tissue, or the pain/sensitivity of pelvic floor muscle trigger points and specific areas of myofascial restriction detected upon palpation in a patient comprising administering to the one or more trigger points of the patient in need thereof a therapeutically effective amount of a calcium channel blocker, or l-arginine, or a combination of a calcium channel blocker and l-arginine, or pharmaceutically acceptable salts, hydrates, solvates and prodrugs thereof; the application of the topical form of the drug can be applied by the patient regularly as part of a self treatment program to heal muscle related pain and muscle related pelvic pain and each optionally together with a corticosteroid such as cortisone of hydrocortisone. The invention further provides methods for myofascial release, trigger point release, and the use of dilators with and without calcium channel blockers for pain conditions.

06/04/15
20150150856 

Novel compounds useful for the treatment of degenerative and inflammatory diseases


The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, diseases involving cartilage degradation, bone and/or joint degradation, for example osteoarthritis; and/or conditions involving inflammation or immune responses, such as crohn's disease, rheumatoid arthritis, psoriasis, allergic airways disease (e.g. Asthma, rhinitis), juvenile idiopathic arthritis, colitis, inflammatory bowel diseases, endotoxin-driven disease states (e.g.

05/28/15
20150148306 

Compositions and methods for the treatment of inflammation


The invention relates to the compounds of formula i or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i, and methods for the treatment of inflammation may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection.

05/28/15
20150147340 

Therapeutic methods for peritoneal carcinomatosis


Described herein are methods and medicaments useful for treating peritoneal carcinomatosis by administering anti-ctgf agents, particularly anti-ctgf antibodies. Methods for prognosing individuals with perinoteal carcinomatosis are also provided.
Fibrogen, Inc.


05/28/15
20150147270 

Constructs for diagnosing and treating inflammatory bowel diseases and colon cancer


The present invention features, inter alia, constructs for the delivery of therapeutic and diagnostic agents to a patient. The constructs can include a nanoparticle, a targeting agent that specifically binds a targeted tissue or cell, a therapeutic moiety, and a hydrogel.
Georgia State University Research Foundation, Inc. Not For Profit Organization


05/21/15
20150141800 

Management, assessment and treatment planning for inflammatory bowel disease


Discussed herein is an image processing device and a corresponding method for assessing inflammatory bowel diseases. A plurality of dynamic mri sequence of images of a bowel that include peristalsis information of the bowel and static mri image(s) of the bowel that identify at areas of inflammation, stenosis, and increased mural thickness of the bowel are processed.
Children's National Medical Center


05/21/15
20150141631 

Pyrazole derivative and use thereof for medical purposes


The present invention provides pyrazole derivatives, uses thereof for medical purposes and so on. More particularly, the present invention relates to pharmaceuticals useful for the prevention or treatment of constipation, which comprise as an active ingredient 3-(3-{4-[3-(β-d-glucopyranosyloxy)-5-isopropyl-1h-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropionamide, or a pharmaceutically acceptable salt thereof.
Kissei Pharmaceutical Co., Ltd.


05/21/15
20150141523 

Compounds for use in the treatment of autoimmune inflammatory disease


And salts thereof is useful in the prophylaxis or treatment of inflammatory bowel disease or other inflammatory autoimmune diseases with similar aetiology involving t-cell proliferation or or function.. .

05/21/15
20150141472 

Aryl-phenyl-sulfonamido-cycloalkyl compounds and their use


The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-phenyl-sulfonamido-cycloalkyl compounds of the following formula (collectively referred to herein as “apsac compounds”). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, in treatment, for example, of inflammation and/or joint destruction and/or bone loss; of disorders mediated by excessive and/or inappropriate and/or prolonged activation of the immune system; of inflammatory and autoimmune disorders, for example, rheumatoid arthritis, psoriasis, psoriatic arthritis, chronic obstructive pulmonary disease (copd), atherosclerosis, inflammatory bowel disease, ankylosing spondylitis, and the like; of disorders associated with bone loss, such as bone loss associated with excessive osteoclast activity in rheumatoid arthritis, osteoporosis, cancer-associated bone disease, paget's disease and the like, etc.; and of cancer, such as a haematological malignancy, a solid tumour, etc..
Pimco 2664 Limited


05/21/15
20150140175 

Human milk permeate compositions and methods of making and using same


This disclosure features human milk permeates and compositions containing the same obtained from fractionated whole human milk. The oligosaccharide rich permeate and permeate compositions of the present invention are useful as nutritional supplements for pre-term and full term infants, for establishing or maintaining gut flora and for treating the symptoms of inflammatory bowel disease..
Prolacta Bioscience


05/21/15
20150140161 

Methods of improving tolerance related to feeding in an infant, toddler, or child


Disclosed are nutritional formulations including predigested fats that can be administered to preterm infants, infants, toddlers, and children for improving tolerance, digestion, and absorption of nutrients and for reducing the incidence of necrotizing enterocolitis, colic, and short bowel syndrome. The predigested fats include fatty acid-containing monoglycerides and/or a fatty acid component..
Abbott Laboratories


05/21/15
20150139990 

Human monoclonal antibody


The invention provides a method for the prophylaxis, improvement, or treatment of inflammatory bowel disease, multiple sclerosis, and psoriasis by administering to a subject an effective amount of an isolated anti-human cd81 antibody capable of binding to a peptide region consisting of the amino acid sequence of amino acid numbers 80 to 175 of seq id no:22.. .
Sumitomo Dainippon Pharma Co., Ltd.


05/14/15
20150133507 

Pharmaceutical compositions comprising glitazones and nrf2 activators


The invention relates to pharmaceutical compositions comprising ppar agonists and nrf2 activators and methods of using combinations of ppar agonists and nrf2 activators for treating diseases such as psoriasis, asthma, multiple sclerosis, inflammatory bowel disease, and arthritis.. .

05/14/15
20150133373 

Transmucosal delivery of engineered polypeptides


Formulations are provided that comprise compounds having inter alia good duration of action, high potency and/or convenient dosing regimens, and a permeation enhancer for transmucosal administration. The compounds are engineered polypeptides which incorporate an albumin binding domain in combination with one or more biologically active polypeptides.

05/14/15
20150133330 

Methods and compositions useful for diagnosing inflammatory bowel disease-associated neoplasia


The present invention relates to the field of biomarkers. More specifically, the present invention relates to the use of micrornas to diagnose and monitor various diseases such as cancer.



Popular terms: [SEARCH]

Bowel topics: Bowel Disease, Inflammatory Bowel Disease, Irritable Bowel Syndrome, Inflammation, Mercaptopurine, Probiotics, Abdominal Pain, Discomfort, Bowel Movement, Gastrointestinal, Ulcerative Colitis, Rheumatoid Arthritis, Jejunal Tube, Spring Mechanism, Small Bowel

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