This page is updated frequently with new Blood-related patent applications.
| Managing insulin administration|
A method includes obtaining blood glucose measurements and blood glucose times of a patient from a blood glucose meter and executing a patient management program configured to display on a screen a graphical user interface having a trend window of the blood glucose measurements on the time line. The patient management program is configured to receive, in the trend window magnifying inputs for a magnification window superimposed on a segment of the timeline to specify a date range for a magnified window.
| Medmobile device|
The medmobile device (mmd), is a medical device or circuit, software, application or app, software program, or platform, that enables a smart phone, tablet, laptop, computer, or any other mobile computer device, to take mobilized blood pressure readings, temperature readings, pulse readings, heart readings (ekg/ecg), and other vital sign readings, of a patient located outside of a heath care facility; and to monitor, track, store, process, the patient's data or information. This is accomplished by a special software app or program installed on a smart phone, tablet, computer, or any other mobile computer device, network, or platform.
Mcleanics Technology Corporation
| Method for acquiring information on cause of prolongation of coagulation time, and device|
The present invention relates to a method for acquiring information on a cause of prolongation of coagulation time. The present invention also relates to a device, a system and a computer program for analyzing blood coagulation..
| Device, determining a fibrinogen level in a blood sample|
The present invention relates to device (10) for determining a fibrinogen level (20) in a sample (22) comprising, a first input for obtaining an attenuance signal (24) over time indicative of a fibrin polymerization of said sample (22), a second input for obtaining a reactant concentration signal (28) over time indicative of a reactant concentration in said sample (22), wherein the reactant is any substance leading to the cleavage of fibrinogen to fibrin, a simulation unit (16) running a model (32) using the reactant concentration signal (28) as an input to provide a simulated attenuance signal (34) over time, and an evaluation unit (18) configured to infer the fibrinogen level (20) of said sample (22) by comparing the attenuance signal (24) over time with the simulated attenuance signal (34) over time.. .
Koninklijke Philips N.v.
| Method and detecting vector-borne diseases in humans|
Screening human subjects for vector-borne disease is provided and carried out using thymidine kinase 1 alone or in combination with c-reactive protein as biomarkers which are measured in a blood sample, and the measurements are used to compute an index that allows a practitioner to compare results from different subjects and between different populations of subjects, and the screening for vector-borne disease can also be used on subjects that are undergoing treatment to monitor the progress of an infection and the results of the treatment.. .
Veterinary Diagnostics Institute, Inc.
| Whole blood measurement method associated to hematocrit (hct) and whole blood measurement circuit thereof|
A whole blood measurement method associated to hematocrit (hct) and a whole blood measurement circuit thereof is applied in the detection of hct of a whole blood sample to be tested. Herein, a time to digital converting circuit (tdc) is used for counting charging time or discharging time of a fixed capacitor and a to-be-tested sample, and a capacitance difference that is related to hct is generated according to the charging time or the discharging time, so as to provide a reference for a whole blood feature test..
Holtek Semiconductor Inc.
| Method and determining markers of health by analysis of blood|
Biomarkers of high blood pressure are measured to identify high blood pressure of the subject based on one or more biomarkers. In many embodiments, the response of the biomarker to blood pressure occurs over the course of at least an hour, such that the high blood pressure identification is based on a cumulative effect of physiology of the subject over a period of time.
| Detecting hematological disorders using cell-free dna in blood|
Techniques are provided for detecting hematological disorders using cell-free dna in a blood sample, e.g., using plasma or serum. For example, an assay can target one or more differentially-methylated regions specific to a particular hematological cell lineage (e.g., erythroblasts).
The Chinese University Of Hong Kong
| Blood sample assay method|
The invention provides an enzymatic method for measuring the concentration of one or more analytes in the plasma portion of a blood derived sample, containing a first and a second component, where said second component interferes with the measurement of said first component. The method includes: i) diluting the sample with a reagent mixture; ii) substantially removing blood cells; iii) using a reagent which serves to temporarily prevent reaction of the second component, to generate a blocked second component; iv) causing the selective reaction of a constituent of each analyte to directly or indirectly generate detectable reaction products, where one of the analytes is the first component; v) monitoring the detectable reaction product or products; vi) relating an amount of the detectable product or products and/or a rate of formation of the detectable product or products to the concentration of each analyte, where the concentration of at least the first component is related to a corresponding detectable reaction product by means of estimating an un-measurable (fictive) endpoint.
| Neurovascular puncture-avoidant sheath|
A device and method for a guidance sheath is provided which is configured to prevent laceration or puncture of nerves, blood vessels and surrounding tissue, during positioning of a coaxially located needle employed for various medical procedures, such as, the administration of an anesthetic blockade, neuromonitoring, electromyography or a therapeutic intervention.. .
Non-cleavable polymer conjugated with alpha v beta 3 integrin thyroid antagonists
Chemical compositions and methods of synthesis thereof. The compositions disclosed and described herein are directed toward and classified as anti-angiogenic thyrointegrin antagonists, which may be capable of reacting with one or more cell surface receptors of the integrin αvβ3 receptor family.
Medicinal composition of extract of seed of emblica officinalis and preparing the same
A composition having an extract of seed of emblica officinalis. Methods of preparing extract of seed of emblica officinalis.
An improved medical implant device directed to, inter alia, (i) avoiding unwanted initial drug “burst” problems, (ii) providing a more level amount of drug delivery, (iii) reducing blood clotting, (iv) reducing the amount of drug material that remains in the implant device, and/or (v) novel materials for an implant device.. .
Therapeutic tissue modulation devices and methods
According to various embodiments, systems, devices and methods for modulating targeted nerve fibers (e.g., hepatic neuromodulation) or other tissue are provided. Systems, devices and methods for cooling energy delivery members are also provided.
Methods and systems for removing tissue from body cavities
A stone or tissue capture device comprises a shaft with a deployable sweeping/containment structure at its distal end. The shaft is adapted to be removably placed over and connected to a conventional endoscope.
Percsys Secured Creditors, Llc
Digital subtraction angiography
Digital subtraction angiography is used to improve the contrast of images of patient vasculature. A non-contrast image is recorded with no contrast medium injected into the patient, and then a succession of contrast images is captured after the injection of a contrast medium.
Koninklijke Philips N.v.
Systems and methods to detect respiratory diseases
Systems and methods for monitoring patients with respiratory diseases are described. A system may include a sensor circuit to sense a respiration signal and at least one hemodynamic signal.
Cardiac Pacemakers, Inc.
Vascular treatment evaluation system, and method therefor
Provided is a system for supporting the treatment of vascular diseases by performing a blood flow simulation based on a medical image, the system comprising: an input unit that reads the medical image, fluid properties and boundary conditions from a data storage unit; a blood flow analysis execution unit that obtains a pressure field and a flow velocity field based on the medical image read by the input unit; a blood flow information calculation unit that calculates, based on the pressure field and the flow velocity field, blood flow information about a specific blood vessel being treated; a vascular treatment risk assessment unit that calculates, based on the calculated blood flow information, the proportion of a blood flow volume flowing into an aneurysm as a risk factor associated with the vascular treatment of the blood vessel being treated; and display units that display the calculation results to a user.. .
Biocompatible implantable sensor apparatus and methods
Enzymatic and non-enzymatic detectors and associated membrane apparatus, and methods of use, such as within a fully implantable sensor apparatus. In one embodiment, detector performance is controlled through selective use of membrane configurations and enzyme region shapes, which enable accurate detection of blood glucose level within the solid tissue of the living host for extended periods of time.
Ischemic precondition treatment equipment and use and method thereof for judging health condition of blood vessels
Disclosed is ischemic precondition treatment equipment and a use and method thereof for judging health condition of blood vessels. A gas way structure (4) is arranged inside a shell of ischemic precondition training treatment equipment.
System and continuous monitoring of blood pressure
The present invention describes a system and method for continuous monitoring of central (aortic) and peripheral blood pressure. The system includes a fully mobile, non-invasive, continuous blood pressure monitoring system that includes one or more biostrip devices affixed on a user, coupled with an application running on a computing device, which is further connected to a web server in the cloud.
Fourth Frontier Technologies Pvt. Ltd.
Blood pressure measurement cuff and sphygmomanometer
A blood pressure measurement cuff includes a clamp mechanism that sandwiches a measurement site. The clamp mechanism includes a first clamp portion having a shape that is curved along a first half of the measurement site and a second clamp portion having a shape that is curved along a second half of the measurement site.
Omron Healthcare Co., Ltd.
Blood flow measurement device
In an embodiment, a controller included in a blood flow measurement apparatus controls a scanner to iteratively scan one or more cross sections of an interested blood vessel. An image forming unit forms a phase image that represents chronological change in phase difference in the one or more cross sections based on data acquired through iterative scan.
Kabushiki Kaisha Topcon
Blood flow measurement device
A scanner of a blood flow measurement apparatus of an embodiment alternately performs first scan and second scan for first and second cross sections both intersecting an interested blood vessel. An image forming unit forms one or more images of the first cross section including a phase image of the first cross section and an image of the second cross section.
Kabushiki Kaisha Topcon
Biometric information processing device, biometric information processing method and non-transitory computer-readable recording medium
A biometric information processing device including: a memory; a processor coupled to the memory and the processor configured to: extract a surface pattern and a blood vessel pattern of a living body from a biometric image; extract a feature point of the surface pattern; and extract a feature of the blood vessel pattern corresponding to a position of the feature point.. .
Biological information recognition apparatus and scanning the biological information recognition apparatus
The present invention relates to a method a biological information recognition apparatus and a method for activating, by the biological information recognition apparatus, a recognition row and a recognition column including a plurality of piezoelectric elements in various patterns. More specifically, the present invention relates to a biological information recognition apparatus which may be used to identify a user by recognizing biological information, such as the fingerprint, blood vessels, and bones of the user and a method for driving the same.
Befs Co., Ltd.
Biomarkers for seizures
The application relates to markers for seizures and epilepsy. Polypeptide expression panels or arrays are provided, comprising one or more probes capable of binding specific polypeptides in blood plasma or blood serum of a mammalian subject.
The Trustees Of The University Of Pennsylvania
Arteriosclerosis and cancer detection method using deoxyhypusine synthase gene as indicator
The present inventors have surprisingly found that a deoxyhypusine synthase (dhps) gene, which was previously reported to correlate with prostate cancer and cervical cancer, is highly responsive to arteriosclerosis or digestive system cancer, whereby the gene can be used as a desired marker for arteriosclerosis or digestive system cancer. The present invention has been accomplished on the basis of this finding.
National University Corporation Chiba University
Strip module and acquiring information of a sample
A method for measuring blood glucose levels by a portable terminal using a strip module is provided. The strip module includes a dye pad having a color that changes in response to a sample applied to the dye pad.
Samsung Electronics Co., Ltd.
Diagnostic assay for tissue transplantation status
A method of detecting circulatory nucleic acids from a transplanted tissue in a transplant recipient, the method comprising: amplifying circulatory nucleic acids from a transplanted tissue in a blood sample from the transplant recipient, and detecting amplification of a copy number deletion (cnd) polymorphism from the transplanted tissue, and related methods for determining the status of a donor tissue transplanted into a recipient.. .
Murdoch Childrens Research Institute
Processing blood samples to detect target nucleic acids
Provided herein are porous polymer monolith materials and processes that enable integration of blood fractionation, specific nucleic acid amplification and/or detection of nucleic acids from whole blood.. .
Processing blood samples to detect target nucleic acids
Provided herein are porous polymer monolith materials and processes that enable integration of blood fractionation, specific nucleic acid amplification and/or detection of nucleic acids from whole blood.. .
Hepatocyte based insulin gene therapy for diabetes
A method and vectors for controlling blood glucose levels in a mammal are disclosed. In one embodiment, the method comprises the steps of: treating the hepatocyte cells of a patient with a first, second or third vector, wherein the first vector comprises a promoter enhancer, glucose inducible regulatory elements, a liver-specific promoter, a gene encoding human insulin with modified peptidase and an albumin 3′utr and lacks an hgh intron, wherein the second vector comprises an hgh intron, glucose inducible regulatory elements, a liver-specific promoter, a gene encoding human insulin with modified peptidase site and an albumin 3′utr and lacks a promoter enhancer, wherein the third vector comprises an hgh intron, glucose inducible regulatory elements, a liver-specific promoter, a gene encoding human insulin with modified peptidase site, an albumin 3′utr and a promoter enhancer and observing the patient's insulin levels, wherein the patient's insulin levels are controlled..
Wisconsin Alumni Research Foundation
Chaotrope- and volatile-free purifying nucleic acids from plasma
The presently disclosed subject matter provides methods and kits for purifying nucleic acids from blood plasma using a functionalized solid phase comprising a silica or polymer backbone and non-chaotropic and ethanol-free buffers.. .
The Johns Hopkins University
Gammadelta t cell expansion procedure
A method for expanding a population of γδ t-cells is provided in which isolated activated peripheral blood mononuclear cells (pbmcs) are cultured in a medium comprising transforming growth factor beta (tgf-β) under conditions in which the production of effector γδ t-cells having therapeutic activity against malignant disease is favored. The use of tgf-β in the production of effector cells in particular vγ9vδ2 t-cells is also described and claimed..
King's College London
Blood plasma and plasma fractions as therapy for tumor growth and progression
The invention relates to treating individuals with cancer by using blood plasma or blood plasma fractions as treatment.. .
Systems and methods for making encapsulated hourglass shaped stents
Systems and methods for the manufacture of an hourglass shaped stent-graft assembly comprising an hourglass shaped stent, graft layers, and an assembly mandrel having an hourglass shaped mandrel portion. Hourglass shaped stent may have superelastic and self-expanding properties.
Expandable lead jacket
Methods, devices and systems for separating an implanted object, such as a lead attached to a cardiac conduction device, from formed tissue within a blood vessel are provided. The methods, devices and systems for separating a lead from the tissue relate to dilating the tissue surrounding the lead from underneath the tissue and/or between the lead and the tissue..
The Spectranetics Corporation
Clot retrieval system
A platform of devices for removing obstructions and other objects within a blood vessel or other interior lumen of an animal is provided. The system may be deployed in the lumen from a catheter(s) and the system includes a proximal hub, and a distal basket comprised of a plurality of cells.
Legacy Ventures Llc
System for and treating aneurysms
An apparatus for treating an aneurysm in a blood vessel includes a wire to be advanced within a tube and an occlusion element disposed on the wire. The occlusion element includes a cover and an inner anchoring member.
Galaxy Therapeutics, Llc
Ultrasonic measurement apparatus
An ultrasonic measurement apparatus includes an ultrasonic probe that emits an ultrasonic wave to the arm, detects a reflected wave from the arm, and outputs an ultrasonic signal, an image processing unit that forms an ultrasonic image on the basis of the ultrasonic signal, and a first display device and a second display device that displays the ultrasonic image, in which the ultrasonic image includes a blood vessel image indicating a blood vessel included in the arm, and a subtractive color needle image indicating a puncture needle inserted into the blood vessel, and in which predetermined colors corresponding to relative positions between the blood vessel and the puncture needle are displayed in the ultrasonic image.. .
Seiko Epson Corporation
Electrical coupling of pulse transit time (ptt) measurement system to heart for blood pressure measurment
Wrist-worn devices and related methods measure a pulse transit time non-invasively and calculate a blood pressure value using the pulse transit time. A wrist-worn device include a wrist-worn elongate band, at least four ekg or icg electrodes coupled to the wrist-worn device for detecting a ventricular ejection of a heart, a photo-plethysmogram (ppg) sensor coupled to the wrist-worn device for detecting arrival of a blood pressure pulse at the user's wrist, and a controller configured to calculate a pulse transit time (ptt) for the blood pressure pulse.
Method and device for determining at least one physiological parameter
The method serves to determine at least one physiological parameter of a patient. A pulse measurement signal of a pulse pressure wave propagating within the blood vessels and emanating from the heart is acquired at a pulse measurement point.
Blood pressure monitoring using a multi-function wrist-worn device
The present invention provides non-invasive devices, methods, and systems for determining a pressure of blood within a cardiovascular system of a user, the cardiovascular system including a heart and the user having a wrist covered by skin. More particularly, the present invention discloses a variety of wrist-worn devices having a variety of sensors configured to non-invasively engage the skin on the wrist of the user for sensing a variety of user signals from the cardiovascular system of the user.
Integrated light emitting display and sensors for detecting biologic characteristics
A bio-sensor device, integrated with a display portion, includes a surface for touching by a body part, such as a finger. A light source, such as an array of leds, emit light through the surface so as to be reflected and partially absorbed by the body part an array of photodetectors detects light reflected back by the body part and generates signals corresponding to an image of the light reflection, which corresponds to the light absorption pattern in the body part.
Light emitter and sensors for detecting biologic characteristics
A bio-sensor device includes a surface for touching by a body part, such as a finger. A light source, such as an array of leds, emit light through the surface so as to be reflected and partially absorbed by the body part an array of photodetectors detects light reflected back by the body part and generates signals corresponding to an image of the light reflection, which corresponds to the light absorption pattern in the body part.
Identification of novel disease states using viscoelastic analysis in the presence of an thrombolytic agent
In some embodiments, the invention provides methods for detecting an aberrant fibrinolysis condition in a patient. The method includes subjecting a blood sample from the patient to a viscoelastic analysis in the presence of a known amount of a thrombolytic agent, to obtain a coagulation characteristic value of the patient; and comparing the coagulation characteristic value of the patient to a coagulation characteristic value of a healthy individual, the coagulation characteristic value of the healthy individual obtained by subjecting a blood sample from a healthy individual to the viscoelastic analysis in the presence of the known amount of the thrombolytic agent, wherein a difference in the coagulation characteristic value of the patient as compared to the coagulation characteristic value of the healthy individual identifies the patent as having aberrant fibrinolysis.
The Regents Of The University Of Colorado, A Body Corporate
Method for collecting medical data
A method for measuring a glucose level of a blood sample by detecting the test medium inside a media slot of a glucometer, reading the test medium inside said media slot, analyzing a result of the reading, generating the glucose level of a blood sample disposed on the test medium, producing digital data representing the glucose level of the blood sample, encoding the digital data within an audio signal; and wirelessly and repeatedly transmitting the digital data until the test medium is removed.. .
The presence of hemozoin as an indicator of malaria in a blood sample is detected by magnetic separation, dissolution and spectroscopic analysis.. .
Haute Ecole De La Communaute Francaise En Hainaut
Methods and compositions for treating amyloid deposits
The present disclosure provides methods of determining a-beta in a mammal before and after treatment of an amyloid disorder, comprising obtaining a first blood sample from the mammal; administering to the mammal a treatment for an amyloid disorder; obtaining a second blood sample from the mammal; quantifying a level of a-beta in the first blood sample and in the second blood sample; and determining the level of a-beta in the mammal before and after treatment of the amyloid disorder.. .
The General Hospital Corporation
Aggregation-assisted separation of plasma from whole blood
Methods for separating blood plasma from whole blood in the absence of performing centrifugation are provided. The method combines mechanical filtration and blood cell aggregation and is adapted for use in poc clinical testing..
The Johns Hopkins University
Method and analyzing individual cells or particulates using fluorescent quenching and/or bleaching
A method for analyzing a blood sample is provided that includes the steps of: providing a blood sample having one or more of each first and second constituents; admixing a colorant with the sample, which colorant is operative to cause the first constituents and second constituents to fluoresce and absorb light; illuminating at least a portion of the sample; e) imaging a portion of the sample; determining a fluorescence value for each the first constituents and second constituents; determining an optical density value for each of the first constituents and second constituents; and identifying the first constituents and the second constituents using the determined fluorescence and optical density values.. .
Abbott Point Of Care, Inc.
Evanescent hemolysis detection
Analyte content in a cell free portion of a body fluid, such as blood, is optically determined without centrifugation or other preliminary steps for separating the cell free portion from the body fluid. A channel is configured for containing a flowing sample of the body fluid along an optical boundary.
Instrumentation Laboratory Company
Cell surface marker depletion in a sample processing device
The disclosure provides methods, devices, and kits for conducting a quantitative analysis of a whole blood sample. Various modifications to the disclosed methods, devices, and kits are described..
Roche Molecular System, Inc.
Detection of human umbilical cord tissue-derived cells
The invention relates to methods for detecting allogeneic therapeutic cells (such as human umbilical cord tissue-derived cells (hutc)) in blood. The methods includes the steps of identifying one or more one or more markers positive for allogeneic therapeutic cells (e.g.
Depuy Synthes Products, Inc.
Method of measuring adaptive immunity
Compositions and methods for measuring adaptive immune receptor (t cell receptor and immunoglobulin) diversity are described, and find uses for assessing immunocompetence and other purposes. Means are provided for assessing the effects of diseases or conditions that compromise the immune system and of therapies aimed to reconstitute it.
Fred Hutchinson Cancer Research Center
Methods and compositions for delivering interleukin-1 receptor antagonist
Methods and compositions generating and using an interleukin-1 receptor antagonist (il-1ra)-rich solution. Methods for generating and isolating interleukin-1 receptor antagonist include incubating a liquid volume of white blood cells and platelets with polyacrylamide beads to produce interleukin-1 receptor antagonist.
Biomet Biologics, Llc
Systems and methods for selective auto-retroperfusion along with regional mild hypothermia
Systems and methods for selective auto-retroperfusion along with regional mild hypothermia. In at least one embodiment of a system for providing a retroperfusion therapy to a venous vessel of the present disclosure, the system comprises a catheter for controlling blood perfusion pressure, the catheter comprising a body having a proximal open end, a distal end, a lumen extending between the proximal open end and the distal end, and a plurality of orifices disposed thereon, each of the orifices in fluid communication with the lumen, and at least one expandable balloon, each of the at least one expandable balloons coupled with the body, having an interior that is in fluid communication with the lumen, and adapted to move between an expanded configuration and a deflated configuration, and a flow unit for regulating the flow and pressure of a bodily fluid, and a regional hypothermia system operably coupled to the catheter, the regional hypothermia system operable to reduce and/or regulate a temperature of the bodily fluid flowing therethrough..
Tearaway sheath introducer and method
Disclosed is a tearaway sheath introducer. The sheath includes a sheath hub disposed on an end thereof, wherein the sheath is configured to receive a dilator therethrough, further wherein the dilator comprises a hub with a locking mechanism.
Vascutech Medical Llc
Devices for assisting with advancement of catheters and related systems and methods
The various embodiments herein relate a catheter advancement device having an elongate shaft and a capsule attached to or integral with the shaft, and related methods for assisting with advancement of catheters such as guiding catheters while reducing damage to the inner wall of the blood vessel. Some capsules have a distal plug portion and a neck portion having a smaller diameter than the plug.
Virtual reality guided meditation with biofeedback
A guided meditation system, such as a virtual reality (vr) guided meditation system, provides biofeedback. Wearable devices (e.g., fitness trackers) record information about a physiological state of a user (e.g., heart rate, blood pressure, sleep, and activity data).
Odyssey Science Innovations, Llc
Intravenous sensing system
An intravenous sensing system includes an intravenous needle that may be inserted into an artery. Thus, the intravenous needle may receive blood from the artery.
Method of ameliorating clotting pathologies and related materials and methods
Methods for reducing blood clotting in a subject are provided, including methods to reduce the risk of and/or treat blot clotting pathologies. Also provided are compositions useful to reduce the risk or treat blood clotting pathologies..
The Ohio State University
Vessel access catheter
The described invention provides endovascular devices that share the following general features: a working segment, a support segment, a working lumen, a support lumen, a side hole, and an angled extension. A described endovascular device includes an outer support catheter and an inner catheter with a side hole optionally containing an angled extension disposed at least partially within the lumen defined by the outer support catheter.
Walzman Innovations, Llc
Medical device for treatment of defective blood vessels, body cavities, and body ducts
A medical device to be inserted in a defect blood vessel, body cavity, or body duct for treatment thereof is disclosed, wherein it comprises an essentially cylindrically formed elongated resilient sheath device (2) wherein it has a distal end (3) and a proximal end (4), wherein said sheath device (2) along its circumferential surface in the axial direction is provided with a slotted opening (5) having connection with a first bore (6) arranged in the axial direction of said sheath device (2), said first bore (6) having the ability to house an elongated fiber body (7), wherein said sheath device (2) has the ability to be clamped around a major part of the perimeter of said fiber body (7), and wherein said sheath device (2) in its axial direction also is provided with a second bore (8) having the ability to house an injection means (9), as well as a kit containing said medical device, and a method for treatment of defective blood vessels, body cavities, and body ducts by use of said medical device.. .
Catheter assembly for blood clots removal
An extension catheter is introduced through the guide catheter and inserted into the treatment area, the extension catheter may have an expandable tip. A suction pump is coupled to the proximal end of the guide catheter to aspirate blood clots or other issue from the treatment location outside the body..
Temporary occlusion of blood vessel using extra-luminal balloon
A method of treating a vessel, such as sclerotherapy, includes moving a short balloon catheter to a position at which a compliant extra-luminal balloon is outside of the vessel at an occlusion site, and between the vessel and a non-compliant bearing surface. The vessel is occluded at the occlusion site by inflating the compliant extra-luminal balloon of the balloon catheter, and bearing an outer surface of the balloon against the vessel and the non-compliant bearing surface.
Cook Medical Technologies Llc
A system and a measuring arterial parameters
The present invention relates to a system for measuring the arterial parameters. The system of the invention comprises a signal unit for providing radio frequency (rf) ultrasound signal and demodulated rf ultrasound signal and of the data relating thereto from the signal acquired therefrom; a detection unit for detecting the presence of blood flow in an artery; an identification unit for identifying the said artery; a processing unit for processing the said data and for providing the distension waveform of the said artery; and an estimating unit for estimating at least one of a plurality of localized arterial parameters of the said artery.
Koninklijke Philips N.v.
Blood pressure measurement device
A blood pressure measurement device includes an annular bracelet that comes into contact with the user's wrist; a display that is disposed on the outer surface of the bracelet and includes a display surface; a camera that is disposed on the outer surface of the bracelet, has an optical axis tilted from the direction of a normal to the display surface, and captures images of the user; a pulse wave sensor that is disposed on an inner surface of the bracelet and detects a pulse wave at the user's wrist; and a processing circuit that estimates the user's blood pressure. The processing circuit calculates a first pulse wave timing from a temporal change in luminance in the cheek region in the images, determines a second pulse wave timing from the detected pulse wave, and estimates the blood pressure from a time difference between the first and second pulse wave timings..
Panasonic Intellectual Property Management Co., Ltd.
Device and system of blood collection, and method thereof
A device for collecting a blood sample is provided. The device includes a collection unit, at least one capillary tube, a vacuum connector, and a storage unit.
Winnoz Technology, Inc.
Insulin delivery system and methods with risk based set points
A method may include obtaining blood glucose level readings over a diurnal period for each of a plurality of days and determining an estimated variability of the blood glucose levels over the diurnal period for the plurality of days. The method may also include modifying, based on the estimated variability of the blood glucose level, a target blood glucose level to a modified target blood glucose level, and delivering insulin, using an insulin pump, during the diurnal period based on the modified target blood glucose level..
Bigfoot Biomedical, Inc.
Method of operating a long-term blood pressure measurement device
The invention relates to a method of operating a long-term blood pressure measurement device having a measurement sensor for detecting a pulse wave signal, having a measurement sensor for body current signals, having a pressure cuff for a non-invasive determination of the blood pressure, having a control and evaluation unit for determining blood pressure values, on the one hand from signals acquired by means of the pressure cuff (pressure cuff signals), and, on the other hand from a pulse wave transit time that is derived from body current signals and pulse wave signals, and having a memory for storing blood pressure values.. .
Muller & Sebastiani Elektronik Gmbh
Non-intrusive portable sleep apnea assessment system
A method of sleep apnea diagnosis includes providing interrogatories at a user interface; receiving responses to the interrogatories at the user interface; receiving blood pressure measurement information from a blood pressure monitoring device; receiving heart rate measurement information from a heart rate monitoring device; and determining, from the responses to the interrogatories, the blood pressure measurement information and the heart rate measurement information, a classification of a subject, the classification being either having sleep apnea disorder or not having sleep apnea disorder.. .
The Regents Of The University Of California
Automated microscopic cell analysis
Disclosed in one aspect is a method for performing a complete blood count (cbc) on a sample of whole blood by metering a predetermined amount of the whole blood and mixing it with a predetermined amount of diluent and stain and transferring a portion thereof to an imaging chamber of fixed dimensions and utilizing an automated microscope with digital camera and cell counting and recognition software to count every white blood cell and red blood corpuscle and platelet in the sample diluent/stain mixture to determine the number of red cells, white cells, and platelets per unit volume, and analyzing the white cells with cell recognition software to classify them.. .
Blood coagulometer and method
An apparatus for determining blood clotting capacity comprises an actuator to cyclically move a member within a sample of blood received in a well in a tray and one of a deflection sensor and a position sensor to determine the position of the wetted member upon being acted upon by the actuator. The theoretical position of the wetted member, as determined using a known actuator force and wetted member physical data, is compared to the sensed deflection or position of the wetted member, and the resistance to movement of the wetted member caused by the blood is determined and correlated to a clotting capacity..
Board Of Regents The University Of Texas System
Microfluidic chip for coagulation sensing
Example implementations relate to coagulation sensing. For example, a microfluidic chip for coagulation sensing may include a microfluidic channel, an outlet at an end of the microfluidic channel having an air interface, and an impedance sensor located within the microfluidic channel and within a particular proximity to the air interface, the impedance sensor to determine a stage of a coagulation cascade of a blood sample flowing through the microfluidic channel to the impedance sensor..
Hewlett-packard Development Company, L.p.
Determining blood glucose in a small volume sample receiving cavity and in a short time period
The concentration of glucose in a blood sample is determined by methods utilizing test strips having a sample receiving cavity having a volume from about 0.3 μl to less than 1 μl and determining the glucose concentration within a time period from about 3.5 seconds to about 8 seconds.. .
Roche Operations Ltd.
Methods and compositions for treating ineffective erythropoiesis
In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.. .
Acceleron Pharma Inc.
Method for treating diabetes and other glucose regulation disorders using stem cells
Various embodiments of the invention provide methods of treating diabetes and other glucose regulation disorders. In one embodiment, the method comprises removing l-cells from a donor, obtaining stem cells from a patient, and culturing the l-cells in the presence of the stem cells under conditions such that the stem cells differentiate into stem cell-derived l-cells (scdlc).
Incube Labs, Llc
Automated microscopic cell analysis
This disclosure describes single-use test cartridges, cell analyzer apparatus, and methods for automatically performing microscopic cell analysis tasks, such as counting blood cells in biological samples. A small unmeasured quantity of a biological sample such as whole blood is placed in the disposable test cartridge which is then inserted into the cell analyzer.
Predicted time to assess and/or control a glycemic state
Presented here are techniques for controlling glucose levels of a patient based on predicted time to a target glucose level. One methodology predicts a trajectory of the blood glucose level based on past observations of the blood glucose level, determines a cost expression based on the trajectory, and affects a future command to an infusion pump to affect a cost value according to the cost expression.
Medtronic Minimed, Inc.
Renal therapy system including a blood pressure monitor
An example renal therapy system includes a blood pressure monitor configured to output blood pressure data concerning a patient and a renal therapy machine communicatively coupled to the blood pressure monitor. The renal therapy machine is configured to generate ultrafiltration (“uf”) removed data from a prescribed renal therapy treatment performed by the renal therapy machine on the patient, and transmit the uf removed data and the blood pressure data via a network.
Baxter Healthcare Sa
Dialysis system including wireless patient data
An example dialysis system includes a dialysis machine and a receiver coded with at least one of an address or a personal identification number (“pin”). The dialysis machine is configured to perform a prescribed dialysis treatment on a patient, generate ultrafiltration (“uf”) removed data over the prescribed dialysis treatment performed by the dialysis machine, and transmit the uf removed data.
Baxter Healthcare Sa
Protein-coupled red blood cell compositions and methods of their use
Methods and compositions for using n-hydroxysuccinimide and n-hydroxysulfosuccinimide to covalently couple protein(s) to the surface of red blood cells universally, rapidly and conveniently are provided. In one embodiment, the compositions promote immune tolerance in a subject.
Augusta University Research Institute, Inc.
Lactococcus lactis strains for producing bioactive peptides having anti-hypertensive and cholesterol-lowering effects
New lactococcus lactis strains, nrrl b-50571 and nrrl b-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides that reduce blood pressure, lower ldl-cholesterol (bad cholesterol) and present antioxidant properties for better cardiovascular health. These biologically active peptides may be produced within the food for the production of a food product, such as a functional food, or they may be produced from protein sources and subsequently added to a food as part of the formulation or as part of a food supplement or a pharmaceutical preparation..
Centro De Investigación En Alimentación Y Desarrollo, A.c. (ciad)
Uses of poria cocos epidermis extract, poricoic acid a, and poricoic acid b in regulating blood glucose level
A method for regulating blood glucose level is provided. The method comprises administering to a subject in need an effective amount of at least one of poricoic acid a and poricoic acid b, wherein at least one of poricoic acid a and poricoic acid b can be used in the form of a plant extract, and wherein in the plant extract, poricoic acid a and poricoic acid b are present in a total amount of at least 30 wt %, based on the total weight of the plant extract..
Sinphar Pharmaceutical Co., Ltd.
Products are described for treating epithelial tissues of the human or animal body including liquid compositions containing whole blood, or parts of blood including blood plasma, blood serum, blood platelets and growth factors derivable from blood. Other compositions disclosed include solid reservoirs of collagen or amniotic membrane into which whole blood or parts of blood have been absorbed.
Inhibiting blood pressure drop in the treatment of erectile dysfunction
Pharmaceutical compositions and formulations are provided herein comprising a phosphodiesterase type 5 inhibitor, such as sildenafil citrate; and, an adenosine receptor (a1, a2a, a2b, and a3 receptors) antagonist, such as caffeine, for (i) treating erectile dysfunction while (ii) inhibiting the lower of the blood pressure, (iii) increasing the bioavailability of the compositions, and (iv) reducing the tmax in the subject. Methods of making and administering oral disintegrating tablets are also provided..
Melatonin-based nasal compositions and uses thereof
Disclosed is an improved composition characterized in containing a combination of melatonin and 5-htp in a nasal administration for the rapid treatment of insomnia, anxiety, and related disorders in mammals, including humans. The present invention relates also to a pharmaceutical composition comprising 5-htp and melatonin which utilizes the known effects of two substances to provide sleep improvement, relaxation, and reduced anxiety via rapid delivery of the combination, via nasal administration, for short-term alleviation of sleep disorder and anxiety-related symptoms.
The Lester Smith Medical Research Institute, Llc
Method of treating hypertension
The present invention relates to methods and composition for treatment of hypertension. Particularly the present invention provides a method of treating hypertension comprising orally administering once a day to a human patient in need thereof the compound valsartan in an extended release dosage form, wherein said extended release valsartan dosage form reduces mean systolic and diastolic blood pressure in a patient during a time period of about 20 hours to about 24 hours after administration to a greater extent than an immediate release formulation of valsartan..
Rubicon Research Private Limited
Methods and composition for treatment of cardiovascular conditions
The present invention relates to methods for treatment of cardiovascular conditions selected from high blood pressure, heart failure, or heart attack. The present invention further relates to a method of treating cardiovascular conditions comprising orally administering once a day to a human subject in need thereof the compound valsartan in an extended release dosage form, wherein the ratio of mean plasma concentration of valsartan provided by the extended release dosage form to the mean plasma concentration of valsartan provided by an immediate release dosage form of valsartan over 8 hour to 24 hour period after administration is greater than 1 in a single dose human pharmacokinetic study..
Rubicon Research Private Limited
Inverting temporary valve sheath
A percutaneous device including a temporary valve attached to a sheath, the sheath having an inverting section for delivery and removal thereof from a blood vessel. The sheath is inverted for delivery, housing the valve between inverted layers thereof.
Valve Medical Ltd.
Magnetic assisted in-situ tubular stentgraft fenestration
A magnet assisted surgical device, system, and method employs magnetic sections, catheters, and guidewires to modify tubular stentgrafts in-situ. One example application provides a more reliable way for surgeons to modify stentgrafts insitu to allow blood flow to continue to branching blood vessels that would otherwise be blocked by the stentgraft itself.
Texas Heart Institute
Artificial blood vessel and preparation method thereof
The artificial blood vessel comprises a cortex layer, a fibroblast layer, a smooth muscle cell layer, an endothelial cell layer and an inner cavity. According to the artificial blood vessel, the endothelial layer, the smooth muscle cell layer, the fibroblast layer and the cortex layer are orderly arranged in a three-dimensional space by utilizing integrated technologies of plasma spraying, electrospraying, electrospining, intra-mold pouring and 3d printing; anticoagulant activity of the artificial blood vessel is enhanced by adopting an anticoagulation factor; step-by-step induced differentiation of stem cells in the artificial blood vessel is realized by adopting a growth factor controlled release method; and the artificial blood vessel is cultured by a pulsatile reactor, so that the artificial blood vessel structurally and functionally simulates natural animal blood vessels and provides a corresponding substitute for vascular transplantation and repair..
Filter and occluder systems and associated methods and devices
Various aspects of the instant disclosure relate to flow devices including filters and occluders for modifying flow in body conduits such as blood vessels. In some examples, such devices include a support structure and a flow media coupled to the support structure.
W. L. Gore & Associates, Inc.
Removable embolus blood clot filter and filter delivery unit
A blood clot filter, collapsible toward a central longitudinal axis into a collapsed configuration for insertion into a blood vessel and radially expandable outwardly from the longitudinal axis to an expanded configuration for contact with the inner wall of the blood vessel at two longitudinal spaced locations. A first plurality of elongate arms, in the expanded configuration, curve outwardly from the longitudinal axis toward the leading end of the filter to form a first filter basket and to center a hub at the trailing end of the filter within the vessel.
C.r. Bard, Inc.
Energy delivery to intraparenchymal regions of the kidney
A method to apply a nerve inhibiting cloud surrounding a blood vessel includes creating a treatment plan, wherein the treatment plan prescribes application of the nerve inhibiting cloud towards at least a majority portion of a circumference of a blood vessel wall, and applying the nerve inhibiting cloud towards the majority portion of the circumference of the blood vessel wall for a time sufficient to inhibit a function of a nerve that surrounds the blood vessel wall.. .
Kona Medical, Inc.
Cardiovascular access and device delivery system
A system and method of accessing a heart of a patient is provided. A cardiac access channel is established through an apical wall of the heart to provide direct access through the apical wall to the left ventricle.
Cedars-sinai Medical Center
Methods and treating embolism
A method and apparatus for treating a clot in the blood vessel of a patient, and particularly the treatment of a pulmonary embolism is disclosed. The treatment includes restoring flow through the clot followed by clot removal, either partially or substantially completely.
Inceptus Medical, Llc
Blood pressure measurement apparatus and blood pressure measurement method
A blood pressure measurement apparatus includes circuitry configured to: detect a pulse of a subject, and obtain a photoplethysmography signal; and obtain estimated blood pressure of the subject based on the photoplethysmography signal. The circuitry receives parameter information, generates time information based on the photoplethysmography signal, applies a blood pressure estimation equation to the time information and the parameter information to calculate the estimated blood pressure, receives basic blood pressure information for the subject and the time information, and performs learning processing of applying a learning operational equation to statistical time information, which is obtained by performing statistical processing on the time information, and the basic blood pressure information to update the parameter information..
Remote monitoring device
A remote monitoring device is connected to a rubber strap and contains: a controller, a global system for mobile communication (gsm), a global positioning system (gps), a wi-fi & blue tooth, and a near field communication (nfc). The controller includes a microprocessor, a blood pressure sensing unit, a heartbeat sensing unit, a temperature sensing unit, and a wireless signal transmitting unit.
Blood analysis method and apparatus
A capillary chamber for performing chemical and physical analysis using a plurality of whole blood samples is presented. Following a loading of the whole blood samples into a plastic tube, the whole blood samples are distributed into a collection chamber and the capillary chamber has means of adding respective vaccines or similar biological products into each capillary tubes.
Blood vessel imaging apparatus and personal authentication system
In the conventional art, there has been a problem that it is difficult to perform, with a high usability and at a high precision, authentication that accepts a wide range of variation of showing attitude of a hand or a finger and ensures obtaining a clear blood-vessel image of a finger. Provided is a blood-vessel image capturing apparatus including an opening portion formed in a surface of a housing, plural light sources disposed beside the opening portion and arranged in a lattice pattern, a sensor configured to obtain position information of a hand shown above the opening portion, a light amount control portion configured to select an irradiation light source to irradiate the hand from the plural light sources on a basis of the position information and control a light amount of the irradiation light source, and an image capturing portion configured to capture an image of a blood vessel included in a finger portion of the hand irradiated with light from the irradiation light source..
Intravascular absorbable stent detection and diagnostic methods and systems
In part, the disclosure relates to systems and methods of detecting struts in a blood vessel. In one embodiment, an intravascular data collection system and an intravascular data collection probe are used.
Lightlab Imaging, Inc.
Systems and methods for non-pulsatile blood volume measurements
This relates to systems and methods for determining one or more of a user's physiological signals. The one or more of the user's physiological signals can be determined by measuring pulsatile blood volume changes.
Dynamic analysis apparatus and dynamic analysis system
A dynamic analysis apparatus may include a setting section which sets a target region in a lung region of a chest dynamic image; a conversion section which calculates a representative value of a pixel signal value in the target region, and converts the pixel signal value; an extraction section which extracts a pulmonary blood flow signal from the image; and a calculation section which calculates a change in the pulmonary blood flow signal, and calculates a feature amount regarding pulmonary blood flow. The setting section may determine a size of the target region based on a size of a body part other than a lung blood vessel, a movement amount of a body part other than the lung blood vessel or subject information of the chest dynamic image, the subject information regarding a subject of the radiation imaging, and the setting section may set the target region..
Konica Minolta, Inc.
System and distinguishing blood components
A method for measuring concentrations of blood cell components is provided. The method comprises: obtaining a blood sample from a subject, the blood sample comprising red blood cells (rbcs), white blood cells (wbcs), and platelets (plts); mixing the blood sample with a non-lysing aqueous solution to form a sample mixture comprising a predetermined tonicity; passing the sample mixture through a flow cell; emitting light towards the flow cell; measuring an amount of light absorbed by the rbcs; measuring an amount of light scattered by wbcs, and plts; determining a concentration of each of the rbcs, wbcs, and plts present in the sample mixture from the measured amount of light absorbed by the rbcs and scattered by the wbcs and plts..
Non-invasive detection of fetal genetic traits
blood plasma of pregnant women contains fetal and (generally >90%) maternal circulatory extracellular dna. Most of said fetal dna contains ≦500 base pairs, said maternal dna having a greater size.
Pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
Pyrazole derivatives of formula (ia) and pharmaceutical compositions thereof that modulate the activity of the serotonin 5ht2a receptor. Formula (ia).
Arena Pharmaceuticals, Inc.
Novel pentadienoyl piperidine derivative and use thereof
The present invention relates to a novel pentadienoyl piperidine derivative, a pharmaceutical composition containing the same for prevention or treatment of metabolic diseases, and a functional food composition using the same for improvement or relief of metabolic diseases. The pentadienoyl piperidine derivative of the present invention inhibits the differentiation of preadipocytes, reduces body weight, visceral fat, blood lipid levels, and blood glucose levels, improves a blood liver function index, and suppresses metabolic inflammation responses.
Snu R&db Foundation
Apparatus and methods for delivering devices for reducing left atrial pressure
A device for regulating blood pressure between a patient's left atrium and right atrium, and apparatus for delivery the device, are provided. The delivery apparatus may include one or more latching legs, a release ring, a pull chord, and a catheter wherein the latching legs are configured to engage the device for delivery.
A dietary fibre composition
The invention provides a composition comprising glucomannan, carrageenan, xanthan gum and a monovalent or divalent cation salt. The composition is suitable for use in managing weight, combating obesity, combating metabolic syndrome, promoting satiety, reducing appetite, combating diabetes, lowering blood cholesterol, lowering blood pressure, reducing postpranial glycaemia, or increasing insulin sensitivity..
Inqpharm Group Sdn Bhd
Methods of treating hemoglobinopathies
Methods of alleviating the symptoms of hemoglobinopathies, including, but not limited to, sickle cell disease, β-thalassemia, and hemoglobin h disease are provided. In some embodiments, the methods comprise administering an inhibitor selected from an erk inhibitor, a mek inhibitor, and, a raf inhibitor.
Ureteral stent for placement in a kidney and bladder
Provided is a ureteral stent (=50) including a bladder portion (=52) positioned in a bladder of a patient, a kidney portion (=54) positioned in a kidney and ureteral passageway of the patient, and one or more tethers (=56) coupling the bladder portion to the kidney portion. The ureteral stent allows urine to pass around a blockage, and allows a ureter orifice connecting the ureteral passageway to the bladder to move between a compressed state and an uncompressed state to prevent or minimize urinary reflux, flank pain, blood in the urine, etc., while allowing the bladder portion to move freely in the bladder to prevent the bladder portion from irritating the trigone muscle..
University Hospitals Health System, Inc.
Endovascular docking apparatus and method
Exemplary embodiments of apparatuses and methods of providing an endovascular′dock within a blood vessel are provided. An apparatus for vascular surgery can be provided, having an external tubular graft capable of expansion and configured to be placed within a sheath in an unexpended state, a first tubular structure provided internally within the external tubular graft and configured for placement of a graft therein, and a second tubular structure provided internally within the external tubular graft and configured for placement of a graft therein.
Blood clot filter with local thrombolytic drug delivery
A thrombus capture and lysis device including a filter sized to be implanted within a blood vessel. The filter includes a plurality of hollow elements defining a mesh sized to span an area of the blood vessel.
Catheter and improved ablation
An ablation electrode is mounted on the distal end of a catheter with a first portion inside and a second portion outside the catheter. The second portion is adapted to have a surface that makes maximum contact with a tissue to be ablated, leaving a minimum area not covered by the tissue and potentially exposed to blood.
Sirona Medical Technologies, Inc.
Removable medical device implantable in blood vessels, particularly in the thoracic aorta with aneurysm
The device is provided with extraction means (5) for extracting the duct (4) from the body of the subject in whom it is inserted. The extraction means (5) are associated with the duct (4) and communicate with the outside of the body..
Lancet device with first-drop removal
A medical puncturing device having a wicking element disposed on a portion of the medical puncturing device is disclosed. The wicking element allows a user to remove a first drop of blood upon puncturing the skin using the medical puncturing device.
Becton, Dickinson And Company
Method and system for determining a blood glucose level for a patient
The present disclosure refers to a method for determining a blood glucose level for a patient, the method comprising detecting a present sensor signal in a present continuous interstitial blood glucose measurement for a patient; providing measurement data representing the present sensor signal; providing sensor signal correction data representing a patient-specific signal correction, the sensor signal correction data being determined from a former interstitial blood glucose measurement for the patient and comprising at least one of time delay data representing a patient-specific time delay Δt between a blood glucose value measured in a continuous interstitial blood glucose measurement and a blood glucose reference value measured in a capillary blood glucose measurement, and sensor sensitivity data representing, for the patient, a patient-specific sensor sensitivity for the sensor, determining corrected measurement data representing a corrected present sensor signal by applying the sensor signal correction data to the present sensor signal; and determining a blood glucose level for the patient from the corrected measurement data.. .
Roche Diabetes Care, Inc.
Electronic device and control method
An electronic device according to one aspect includes a blood flow data acquisition unit configured to acquire information related to blood flowing inside a living body as blood flow data based on doppler shift, a power spectrum calculator configured to calculate a power spectrum of the blood flow data based on the blood flow data, and an outline index calculator configured to calculate an outline index from the power spectrum. An electronic device according to one aspect further includes an estimator configured to estimate viscosity of the blood based on the outline index, and the estimator is configured to display an estimation result of the viscosity of the blood on a display..
Method of calculating blood pressure using a mobile device
Apparatus and associated methods relate to determining a user's blood pressure via information collected by a camera and a microphone of a portable communication device (pcd). In an illustrative example, the pcd simultaneously records a blood flow and a pulsation for the user.
Smn Medical P.c.
Device for analyzing insulin secretion ability, system for analyzing insulin secretion ability provided with same, and analyzing insulin secretion ability
The present invention enables evaluation of insulin secretion ability by a simpler method. A device for analyzing insulin secretion ability that comprises: an input unit inputting at least a fasting blood sugar level and an hba1c level; an estimated hba1c calculation unit calculating an estimated hba1c level from the inputted fasting blood sugar level and hba1c level; and an evaluated insulin secretion ability calculation unit calculating an evaluated insulin secretion ability on the basis of the hba1c level inputted by the input unit and the estimated hba1c level calculated by the estimated hba1c calculation unit..
Method for determining risk of diabetes
A method of determining risk of diabetes is provided. In one embodiment, the method comprises: a) measuring the levels of a plurality of biomarkers in a blood samples obtained from a patient, wherein the plurality of biomarkers comprises at least five of the following biomarkers: glucose, adiponectin, crp, il2ra, ferritin, insulin and hba1c; b) calculating a diabetes risk score for the patients using the levels and, optionally, patient age and/or gender.
Methods for blood typing and antibody screening
The invention features systems and methods for the detection of analytes, particularly antigens, complement, and antibodies present in blood. The invention features a system for the detection of antigens, complement, and antibodies on the surface of rbcs and circulating antibodies in the blood..
Diagnostic of obliterative arteriopathies
The invention relates to a method of diagnosis or prognosis of an obliterative arteriopathy in a subject, comprising determining the expression level of adenosine a2a receptors expressed at the cell surface of peripheral blood mononuclear cells obtained from said subject. The invention also relates to an agonist-like monoclonal antibody directed to the human adenosine a2a receptor, useful for carrying out this method..
Systems and methods for neuromodulation of sympathetic and parasympathetic cardiac nerves
A catheter system configured for delivering a neuromodulation therapy, includes a first therapeutic element positionable in a first target vessel selected from the group of blood vessels consisting of the superior vena cava, left brachiocephalic vein, right brachiocephalic vein, azygos vein or azygos arch, and a second therapeutic element in a second target vessel selected from the group of blood vessels consisting of the superior vena cava, left brachiocephalic vein, right brachiocephalic vein, internal jugular vein, azygos vein or azygos arch. The system and associated method deliver therapeutic energy to at least one parasympathetic nerve fiber external to the first target vessel using the first therapeutic element, and deliver therapeutic energy to at least one sympathetic nerve fiber external to the second target vessel using the second therapeutic element..
System and relieving high blood sugar factor of diabetes
A system and method for relieving high blood sugar factor of diabetes includes an energy wave generator with an energy wave's frequency control mode. The energy wave's frequency control mode includes multiple controls for controlling and generating energy waves with corresponding energy densities to effect on diabetic patient's body, so as to reduce and eliminate the high blood sugar factors of the diabetic patient..
Systems and methods for treating a carotid artery
Systems and methods are adapted for treating the carotid artery. The systems include interventional catheters and blood vessel access devices that are adapted for transcervical insertion into the carotid artery.
Device and regulating pressure in a heart chamber
A device for regulating blood pressure in a heart chamber is provided. The device includes a shunt positionable within a septum of the heart.
Method for enhanced uptake of viral vectors in the myocardium
The present invention relates to improved therapies for the treatment of heart disease, particularly the improved delivery of therapeutic agents to heart tissue by direct infusion into the coronary circulation. A preferred embodiment of the invention is a method of treating or preventing a cardiovascular disease by transfecting cardiac cells of a large mammal, the method comprising, identifying a mammal in need of treatment or prevention of heart disease, supplying no to the coronary circulation prior to, and/or during the infusion of a therapeutic polynucleotide into a blood vessel of the coronary circulation in vivo, where the therapeutic polynucleotide is infused into the blood vessel over a period of at least about three minutes, where the coronary circulation is not isolated or substantially isolated from the systemic circulation of the mammal; and where the therapeutic polynucleotide transfects cardiac cells of the animal resulting in the treatment or prevention of the heart disease..
Composition, containing high-hardness mineral water prepared from salty underground water or deep-sea water, for preventing or alleviating decrease in blood pressure or symptoms related thereto
The present invention relates to a composition, containing, as an active ingredient, high-hardness mineral water prepared from salty underground water or deep-sea water, for preventing or alleviating a decrease in blood pressure or symptoms related thereto. According to the present invention, the high-hardness mineral water prepared from salty underground water or deep-sea water, especially, prevents a rapid decrease in blood pressure or mitigates the degree of decrease in blood pressure, during or after exercise, and thus can be used to prevent or alleviate symptoms related to a rapid decrease in blood pressure during or after exercise..
Use of nitrite salts in chronic ischemia
Methods of treating a subject who has chronic tissue ischemia are disclosed. The methods can include administering to the subject a pharmaceutical composition comprising inorganic nitrite or a pharmaceutically acceptable salt thereof, for a time and in an amount sufficient to result in blood vessel growth in the ischemic tissue.
Method for improving interstitial flow
Provided is a prophylactic and/or therapeutic drug for mild cognitive impairment, which can improve interstitial flow in cerebral blood vessel and the like to achieve sufficient clearance of harmful proteins accumulated in the brain. The prophylactic and/or therapeutic drug includes 6-[4-(1-cyclohexyl-1h-tetrazole-5-yl)butoxy]3,4-dihydrocarbostyril or a salt thereof as an active ingredient.
S isomers of alpha-methyl-hydrocinnamic acid for the treatment of blood disorders
The present intervention generally relates to compositions comprising s-isomer of alpha-methyl-hydrocinnamic acid for the treatment and/or prevention of blood disorders and blood deficiencies, as well as methods for treating blood disorders and/or blood deficiency in a subject by administering a composition comprising s-isomer of alpha-methyl-hydrocinnamic acid to the subject to ameliorate at least one symptom associated with the blood disorder. Another aspect relates to administration of an s-isomer of alpha-methyl-hydrocinnamic acid stimulate multi-lineage hematopoietic cell production in a subject, for example, increasing the numbers of circulating neutrophils, erythrocytes and platelets.
Heart valve prosthesis
A heart valve prosthesis includes a valve frame (2), on which frame several valve leaflets (8) are fastened, as well as a fastening region which connects axially onto the valve frame (2), for fastening in a blood vessel. The fastening region includes a stabilizing ring (14, 14′, 14″, 14″′, 14″″) which defines a given shape and a given diameter and is connected to the valve frame (2) is a force-decoupled manner..
Method of reshaping a body part
A method of reshaping a body part including the step of injecting a quantity of filler material into a subperiosteal plane of a facial region thereby depositing a body of filler between the periosteum and bone of the facial region. The method includes the step of piercing a periosteum of the facial region with a syringe.
Blood vessel dissecting device
A blood vessel dissecting device is disclosed, which includes a dissecting device which, when being inserted into a living body along a blood vessel, dissects tissue in a direction of alignment thereof with the blood vessel, and a cutting device which, when being inserted into the living body along the blood vessel, cuts tissue surrounding the blood vessel in a direction of alignment thereof with the blood vessel. The cutting device includes a main body section which is inserted into the living body and holds the tissue between itself and the dissecting device, and a cutting section which cuts the tissue held between the main body section and the dissecting device..
Blood vessel dissecting device and blood vessel dissecting method
A blood vessel dissecting device is disclosed, which includes at least two dissecting devices, which are inserted into a living body along a blood vessel to dissect tissue in a direction of alignment thereof with the blood vessel. The at least two dissecting devices include a first dissecting device and a second dissecting device.
Spectrum-neutral determination of calcareous deposits in blood vessels
A method is described for the determination of a calcium score for a patient to be examined with the aid of a ct system. The method is used to define patient-specific ct-acquisition parameters.
Blood-flow analysis device for blood-flow simulation, method therefor, and computer software program
The present method is a method for executing a computational fluid analysis on a blood flow in a computation object region, and displaying the analysis results, comprising the steps of: obtaining, by a computer, blood vessel shape data extracted from medical images; causing, by the computer, a user to specify a computation object region from the blood vessel shape data; retrieving, by the computer, a template according to the specified computation object region, wherein the template stores computation conditions validated for a blood flow analysis of the specified computation object region; and executing, by the computer, the computational fluid analysis of the blood flow in the computation object region by applying the computation conditions to the blood vessel shape data, and outputting the analysis results.. .
Systems and methods for non-invasive blood pressure measurement
Systems and methods for non-invasive blood pressure measurement are disclosed. In some embodiments, a system comprises a wearable member configured to generate first and second signals (e.g., ppg signals), and a blood pressure calculation system.
System and adjusting the blood glucose level of a person
A system for adjusting blood glucose level including an insulin delivery device configured to release insulin into the body of a person, and an eeg monitor having an eeg sensing part including eeg electrodes. The eeg monitor can be arranged in the ear region of the person with the eeg sensing part arranged subcutaneously at the scalp or arranged in the ear canal.
Blood-vessel recognition device and surgical treatment device
A surgical treatment device is provided with: an action portion; a light emitting part that radiates laser light onto living tissue; a light receiving part that receives scattered light of the laser light scattered by the living tissue; a light detection unit that detects the intensity of the scattered light received by the light receiving part; a frequency analysis unit that obtains time-series data indicating a temporal change in the intensity of the scattered light detected by the light detection unit, to extract an amount of frequency spectrum shift of the scattered light, included in the time-series data; and a determination unit that determines a feature of a blood vessel in the living tissue on the basis of the amount of frequency spectrum shift.. .
Method for glucose monitoring
A method for non-invasive glucose monitoring includes the following steps. At least one ray of light is emitted from at least one light source.
Systems and methods for revascularization assessment
Disclosed herein are systems and methods for revascularization assessment. The methods can in some cases include one or more of the steps of measuring blood perfusion as a function of time to obtain time series data, mathematically transforming the time series data into a power spectrum, calculating at least one parameter of the power spectrum within a specific frequency range, and using the at least one calculated parameter as a discriminator for the first population and the second population..
Air circuit structure, blood pressure measuring instrument thereof, and air circuit box
An air circuit structure comprises the air circuit box, an air charging pump, a cuff air nozzle, air discharging valves and an air pressure examination sensor. The air circuit box comprises a shell with a cavity formed inside.
Automated intravascular plaque classification
Methods and apparatus automatically classify intravascular plaque using features extracted from intravascular optical coherence tomography (ivoct) imagery. One example apparatus includes an image acquisition circuit that accesses a set of ivoct images, a pre-processing circuit that generates a blood vessel mask based on the ivoct images, a feature extraction circuit that defines a three dimensional (3d) volume of interest centered on a location in a member of the set of ivoct images, a classification circuit that generates a classification based on a probability that a voxel represents a type of plaque, and a visualization circuit that provides a visualization, substantially in real time, of a member of the set of ivoct images and the classification, where the visualization includes a sector classification image, a labeled image, or a 3d visualization.
Case Western Reserve University
Retinal image processing
The disclosure relates to a non-transitory computer-readable storage medium storing computer program instructions which, when executed by a processor, cause the processor to process image data defining an image of a retina to determine a location of an anatomical feature of the retina in the image by receiving the image data; calculating, for each of a plurality of pixels of the image data, a respective local orientation vector indicative of the orientation of any blood vessel present in the image; calculating a normalised local orientation vector for each of the plurality of pixels; operating on an array of accumulators, wherein each accumulator in the array is associated with a respective pixel of the image data; and determining the location of the anatomical feature in the image of the retina using the location of a pixel of the image data which is associated with an accumulator having accumulated an accumulated value.. .
Retinal image processing
The present disclosure relates to a computer-readable storage medium storing instructions that can cause a processor to process image data defining an image of a vascular structure of temporal vascular arcades of a retina to estimate a location of the fovea of the retina in the image by transforming received image data such that the vascular structure in the image defined by the transformed image data is more circular than the vascular structure defined by the image data; calculating, for each of a plurality of pixels of the transformed image data, a respective local orientation vector indicative of the orientation of any blood vessel present in the image; calculating a normalised local orientation vector for each of the pixels; operating on an array of accumulators; and estimating the location of the fovea in the image of the retina using the location of a pixel of the transformed image data.. .
Methods, systems, and produtcs for measuring health
Methods, systems, and products measure health data related to a user. Often times a weight scale, blood pressure monitor, or other medical measurement device is shared among a group of users.
At&t Intellectual Property I, L.p.
Dixon mr imaging with suppression of flow artifacts
The invention relates to a method of mr imaging of a body (10) of a patient. It is an object of the invention to provide a method that enables efficient compensation of flow artifacts, especially for mr angiography in combination with dixon water/fat separation.
Koninklijke Philips N.v.
Diagnosis of cancer
A method is provided including obtaining an infrared (ir) spectrum of a blood plasma sample by analyzing the blood plasma sample by infrared spectroscopy, and based on the infrared spectrum, generating an output indicative of the presence of a solid tumor or a pre-malignant condition. Other applications are also described..
Todos Medical Ltd.
Binding assay analysis
Methods for determining a sample concentration of target entities in a sample, for example, determining a concentration of target antigens or antibodies in a blood sample or other biological sample.. .
Measuring volume and constituents of cells
A method for determining a mean cell volume for a blood sample includes: illuminating the sample with incident light at a plurality of illumination wavelengths and obtaining a two-dimensional image of the sample at each of the plurality of illumination wavelengths; identifying a plurality of cells that appear in each of the images; for each one of the plurality of cells, determining an integrated optical density corresponding to each of the plurality of illumination wavelengths; for each one of the plurality of cells, determining a cell volume based on the integrated optical densities corresponding to each of the plurality of illumination wavelengths; and determining the mean cell volume for the blood sample from the cell volumes for each one of the plurality of cells.. .
Roche Diagnostics Hematology, Inc.
System and multiplexed affinity purification of proteins and cells
In accordance with an embodiment of the invention, there is provided a method for: a) high-throughput, multiplexed, affinity-based separation of proteins—especially low abundance proteins—from complex biological mixtures such as serum; and b) high-throughput, multiplexed, affinity-based separation of cells—especially rare cells—from complex biological mixtures such as blood or blood fractions. The separation of proteins or cells is achieved based on differential binding to affinity-capture beads of different sizes and then sorting the protein-bound or cell-bound beads using the concept of centrifugal-induced dean migration in a spiral microfluidic device.
The Massachusetts General Hospital
Sensor container for mounting a temperature sensor, and associated refrigerator
A refrigerator for storing products includes a sensor container configured to position at least one temperature sensor within a refrigerated interior in a cabinet of the refrigerator. The sensor container includes a main body portion enclosing a hollow interior space configured to receive a ballast liquid, and a plurality of dry wells which each extend generally horizontally between a closed end within the hollow interior space and an open end.
Thermo Fisher Scientific (asheville) Llc
An implantable assembly is described for acquisition of neuronal electrical signals at a selected location which propagate along at least one nerve fiber contained in a nerve fiber bundle, as well as for selective electrical stimulation of the at least one nerve fiber, having: an implantable electrode assembly (e) which is disposed on a biocompatible support substrate which can be positioned around the nerve fiber bundle in a cuff, which has a cylindrical support substrate surface (i) which in the implanted condition is orientated facing the nerve fiber bundle, on which a first electrode assembly for locationally selective acquisition of the neuronal electrical signals and selective electrical stimulation of the at least one nerve fiber, and on which a second electrode assembly is disposed to record an ecg signal, and an analysis and control unit (a/s) which can be electrically conductively connected or is connected to the implantable electrode assembly (e), in which the locationally selective acquired neuronal electrical signals as well as the ecg signal can be analyzed in a time-resolved manner such that a neuronal time signal correlated with a physiological parameter, such as blood pressure, can be derived.. .
Hydrogel prodrug for treatment
Aspects of the invention described herein include a hydrogel prodrug and methods of making a hydrogel prodrug for drug delivery. Also contemplated are methods of treating, inhibiting, ameliorating or inhibiting a disease or disorder.
Viking Scientific, Inc.
Method for treating hyperglycemia with glp-1
A method for treating hyperglycemia and/or diabetes in a subject is provided. In particular, the method is directed for the treatment of patients with type 2 diabetes mellitus who have a fasting blood glucose concentration greater than about 8 mm, wherein the patient is administered a formulation comprising a glp-1 molecule and a diketopiperazine by pulmonary inhalation with a dry powder inhalation system..
Halogenated insulin analogues of enhanced biological potency
An insulin molecule comprises an asp substitution at position b10, glu at one or more of positions corresponding to a8, b28, and b29, and a halogenated phenylalanine at position b24. The analogue may optionally include (i) n-terminal deletion of one, two or three residues from the b chain, (ii) a mono-peptide or dipeptide c-terminal extension of the b-chain containing at least one acidic residue, and (iii) other modifications known in the art to enhance the stability of insulin.
Case Western Reserve University
Methods of using potassium channel inhibitors (blockers) for fluid resuscitation
Methods and pharmaceutical treatments of fluid resuscitation in which a selective potassium channel inhibitor is administered to a patient in a therapeutic amount sufficient to stabilize blood pressure and/or to reduce the amount of the resuscitation fluid otherwise required to resuscitate the patient.. .
Loyola University Of Chicago
Novel compounds supports hematopoietic stem cells and red blood cells
The present disclosure relates to methods of using a compound to induce regeneration of hematopoietic stem cells or increase the recovery of red blood cells. In some aspects, the present methods can be used to with or in place of erythropoietin in patients to mitigate the side effects of erythropoietin..
The Board Of Regents Of The University Of Texas System
Pharmaceutical formulations of pegylated liposomes and blood coagulation factors
The present invention provides a pharmaceutical composition for subcutaneous administration comprising a blood factor and a colloidal particle comprising about 0.5 to 20 mole percent of an amphipathic lipid derivatized with a biocompatible hydrophilic polymer, wherein the blood factor is not encapsulated in said colloidal particle.. .
Cantab Biopharmaceuticals Patents Limited
Grid pattern laser treatment and methods
Embodiments of the invention provide systems and methods for treating the retina and/or other areas of a patient's eye. The procedures may involve using one or more treatment beams (e.g., lasers) to cause photocoagulation or laser coagulation to finely cauterize ocular blood vessels and/or prevent blood vessel growth to induce one or more therapeutic benefits.
Procedures for vascular occlusion
A method of reducing blood flow within an aneurysm includes: injecting a contrast agent into a blood vessel including an aneurysm; expanding a stent, from a delivery device, across the aneurysm; and confirming that a stagnated area forms in the aneurysm. The stagnated area can form a crescent shape, a mushroom shape, a hemispherical shape, and/or a flat side.
Bone scaffold improvements
Bone graft scaffold arrangements are described that can be used in minimally invasive posterolateral spinal fusion. The bone graft scaffold apparatus comprise a housing which comprises a cavity for receiving bone growth promoting materials and a plurality of apertures.
Methods and systems for controlling blood pressure
Systems and methods for controlling blood pressure via electrical stimulation of the heart are disclosed. Embodiments may include at least two different stimulation patterns, each configured to reduce blood pressure to a different degree, and may alternate between stimulation patterns based on the need of a patient, for example, alternating between day and night or between periods of strenuous and light activity.
Backbeat Medical, Inc.
Dissection prosthesis system and method
A dissection prosthesis system for implantation within a blood vessel includes a first prosthesis and a second prosthesis. The first prosthesis includes a first stent ring, a second stent ring, a first graft material band coupling the first stent ring to the second stent ring, a third stent ring, and a second graft material band coupling the second stent ring to the third stent ring.
Medtronic Vascular, Inc.
Hybrid catheter for vascular intervention
A catheter for debulking of an undesired deposit from an inner surface of at least one of a blood vessel wall and a stent located in a blood vessel, the catheter having a tip section comprising: circumferentially-directed laser optics; and a circular-action cutter, wherein said circumferentially-directed laser optics is configured to transmit laser radiation for modifying an area of the undesired deposit thereby preparing said area for penetration of said cutter, wherein said cutter is configured to cut through said modified area and thereby debulk at least a part of the undesired deposit. In addition, a catheter for pacemaker and icd (implantable cardioverter defibrillator) lead extraction is disclosed..
Eximo Medical Ltd.
Thrombectomy device, extraction of vascular thrombi from a blood vessel
A thrombectomy device including a delivery catheter; a tapered dilator catheter configured to be movably disposed within the delivery catheter; and an expandable aspiration funnel configured to be movably disposed within the delivery catheter in a retracted position and at least partially outside the delivery catheter in an extended position, the funnel comprising a non-permeable covering, a diameter of a distal end of the funnel being greater in the extended position than in the retracted position, the funnel being configured to adapt its shape and length to a surrounding blood vessel such that the funnel lengthens as it narrows to retain a thrombus within the funnel. The invention also includes methods of using the device..
Anaconda Biomed, S.l.
Systems and methods for attaching a prosthesis within a body lumen or hollow organ
Systems and methods introduce and prosthesis into a blood vessel or hollow body organ by intra-vascular access. The prosthesis is secured in place by fasteners which are implanted by an applier that is also deployed by intra-vascular access.
Medtronic Vascular, Inc.
Feces color detection device
A plurality of color sensing sections are attached to a toilet seat so as to test a health state or a fecal occult blood portion every time by capturing the feces surface color during defecation. Before feces which have been excreted from a body sink into a water-seal portion, the circumference of the feces is optically captured to detect the color of the surface of the feces.
Setech Co., Ltd.
Handheld biometric sensor for mobile devices
A system and method comprises structure for receiving in a handheld device biometric or environmental data from the vicinity of the handheld device. The system may include a handheld mobile device such as a cellular telephone, or that device and a separate mechanical housing configured be held in a hand of a user and to clamp to or contain the handheld device.
Intelligent dental ornament and using the same
The invention provides an intelligent dental ornament and a method of using the same, the intelligent dental ornament comprising: a dental ornament body with a cavity, a tester located within the cavity and for detecting a physiological parameter, a battery used by the tester, and a trigger switch for triggering the tester to start test; the dental ornament body is further provided with a through-hole for at least one pipette of the tester stretching out of the dental ornament body, and a sealing cover for sealing the through-hole. When the trigger switch activates the tester, the sealing cover is opened, and the pipette of the tester stretches out of the dental ornament body through the through-hole to obtain the saliva of the subject, and the physiology parameter in the saliva is detected, and the detection result is sent to an external device in communication with the tester.
Boe Optical Science And Technology Co., Ltd.
Apparatus and methods for imaging blood vessels
Various portable systems, devices and methods for imaging or visualizing blood vessels or other body tissue to facilitate accurate placement of a needle or other elongate instrument in blood vessels or other body tissue are described herein. In certain variations an imaging system for aiding needle insertion in a patient may include a mountable unit having an illumination source, an image sensor, and a display for displaying an image based on image information from the image sensor.
Health tracking device
A device may receive, from a plurality of sensors, sensor data relating to a user. The device may include a plurality of types of sensors including a spectrometer and one or more of an accelerometer, a heart rate sensor, a blood pressure sensor, a blood sugar sensor, a perspiration sensor, a skin conductivity sensor, or an imaging sensor.
Viavi Solutions, Inc.
Blood pressure meter and less individual dependent cuff thereof
A blood pressure cuff less dependent on individual's arm shape with downsized dimensions is introduced with medical approval accuracy. The present invention comprises an occlusion component configured to occlude the artery, and a flexible plastic core to limit the degree of freedom of said occlusion component towards body portion, and a spacer occupying the volume between said core and said occlusion component to improve the compliance towards body portion..
Method and device for detecting blood flow rate
A method and device for detecting a blood flow rate are disclosed. The method comprises steps: providing a detection light source, and projecting a light of the detection light source onto a skin of a living body and reach a blood vessel; using a photo sensor to receive a plurality of polarized light beams which are formed by the light of the detection light source reflected by expanding or contracting the blood vessel, wherein the photo sensor respectively generates a first ppg signal and a second ppg signal in blood vessel expansion and contraction; using a microprocessor to acquire at least one first ppg signal and at least one second ppg signal, calculating an offset of received light beams and a time derivative thereof according to a sequence of the first ppg signal and the second ppg signal, and converting the offset and time derivative into a blood flow rate..
Non-invasive blood pressure monitors, methods and computer program product of operating the same
Method of operating a non-invasive blood pressure, nibp, monitor to measure the blood pressure of a subject, the nibp monitor comprising a cuff, a pressure sensor for measuring the pressure in the cuff and for outputting a pressure signal representing the pressure in the cuff and a physiological parameter sensor, the method comprising obtaining a first measurement of pulse rate or heart rate for the subject during inflation of the cuff, the first measurement being obtained from the pressure signal; obtaining a second measurement of the pulse rate or heart rate for the subject during inflation of the cuff, the second measurement being obtained from the physiological parameter sensor; comparing the first measurement and the second measurement; and estimating the reliability of a blood pressure measurement obtained by the nibp monitor during inflation of the cuff based on the result of the step of comparing.. .
Koninklijke Philips N.v.
Delicious garlic shakes and smoothies
These delicious shakes or smoothies, has the active compound called allicin, which comes from the garlic. Allicin is the key ingredient for helping to lower our metabolic risk factors.
Method, apparatus, and system to identify branches of a blood vessel
In part, the disclosure relates to an automated method of branch detection with regard to a blood vessel imaged using an intravascular modality such as oct, ivus, or other imaging modalities. In one embodiment, a representation of a-lines and frames generated using an intravascular imaging system is used to identify candidate branches of a blood vessel.
Methods and compositions related to lipoproteins in blood samples
Methods and compositions related to lipoproteins reactions are provided. Particularly, quantitation of lipoprotein subgroup particle numbers may be used to detect lipoprotein's response to oxidation conditions and incubation conditions.
Method of assessing disease condition of cancer
A method, system and computer-readable medium for assessing a disease condition of a cancer of a subject, including: receiving a blood sample from the subject; isolating a plurality of circulating tumor cells (ctcs) from the blood sample; measuring at least one of cell or cell nucleus sizes of each of the plurality of ctcs; determining a measured ctc size distribution of the plurality of ctcs based on the measuring; comparing the measured ctc size distribution to a reference ctc size distribution using a computer; and assigning the disease condition of the cancer of the subject based on the comparing.. .
Apparatus, method, system for the determination of the aggregation rate of red blood cells
The present invention generally relates to an apparatus, method, system for the determination of the aggregation rate of red blood cells. More specifically, the invention concerns a method, system, and the relative apparatus used to determine the aggregation rate of red blood cells, and other parameters related to these, such as viscosity, deformability, elasticity, density, in the field of in vitro medical analyses, using optical systems after or during inducted forces for red blood cell disruption and redistribution generated by ultrasound waves..
Host and intestinal microbiota derived metabolomic blood plasma signature for prior radiation injury
Provided are methods of determining prior radiation dose exposure levels for subjects, and kits therefor. Also provided are methods of treatment..
Bacteria identification and antibiotic susceptibility profiling device
The system described herein for bacterial identification can be used as a point-of-care or lab-based diagnostic system. In some implementations, the system can be used to detect other foreign agents within blood or other samples.
Device and separating cells
The invention relates to devices, methods and kits for separating biological materials, particularly populations of cells of different densities. The invention finds particular utility in the separation of blood into its different component parts or cellular populations.
Methods and apparatuses for stimulating blood vessels in order to control, treat, and/or prevent a hemorrhage
Methods of preventing, treating, and/or controlling a hemorrhage in an organ of a patient include providing electrical stimulation to the arteries, veins, nerves innervating the arteries or veins, or walls of the organ. The apparatus has at least one electrode operably connected to a stimulus generator and placed in electrical communication with an artery, vein, nerve, or organ wall.
Methods, systems, and computer readable media for physiology parameter-invariant meal detection
Methods, systems, and computer readable media for physiology parameter-invariant meal detection are disclosed. According to one system, the system includes at least one processor and a meal detection module implemented using the at least one processor.
Blood component separation device
A blood component separation device for separating a plurality of blood components from blood sampled from a blood donor, and collecting platelets, includes: an donor calculation unit that calculates a predicted platelet recovery rate from a hematocrit value of the blood and a platelet concentration of the blood, and calculates a recommended processing amount of the blood recommended for collecting a target number of units of platelets on the basis of the calculated predicted platelet recovery rate, wherein the operating unit sets the predicted platelet recovery rate calculated from any the hematocrit value and any the platelet concentration to be smaller by a predetermined value α when the blood donor is female than that when the blood donor is male.. .
Composite preparation, containing novel 3-(4--(benzyloxy)phenyl)hex-4-inoic acid derivative and another active ingredient, for preventing or treating metabolic diseases
The present invention relates to a pharmaceutical composition for preventing or treating metabolic diseases, in which a novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative and at least another active ingredient, which is selected from the group consisting of dipeptidyl peptidase-4 (dppiv) inhibitor-based, sulfonylurea-based, thiazolidinedione (tzd)-based, biguanide-based, and sodium/glucose cotransporter 2 (sglt2) inhibitor-based drugs, may be administered in combination or in the form of a composite preparation. The use of the composition of the present invention can provide a remarkably excellent blood sugar reducing effect in various animal diabetic disease models, and the composition of the present invention can be favorably used as a pharmaceutical composition for preventing or treating metabolic diseases, such as obesity, diabetes type i, diabetes type ii, glucose intolerance symptoms, insulin resistance symptoms, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, dyslipidemia, and syndrome x..
Administration of berberine metabolites
In various implementations, berberine metabolites, such as dihydroberberine and/or tetrahydroberberine, may be administered to manage blood glucose levels, increase ketone levels (e.g., blood concentration of ketones), and/or for therapeutic purposes in humans. The administration of a pharmaceutically effective amount of berberine metabolites, such as dihydroberberine, may reduce fasting blood glucose levels, improve glucose tolerance, and/or improve blood ketone response.
Administration of butyrate, beta-hydroxybutyrate, and related compounds in humans
In various implementations, beta-hydroxybutyrate, related compounds, and/or one or more other compounds may be administered to an individual to cause weight loss, weight maintenance, elevate blood ketone levels, maintain blood ketone levels, reduce blood glucose levels, maintain blood glucose levels, improve energy, focus, mood, cognitive function, or aide with neurological or inflammatory disorders and/or combinations thereof. Other compounds may include short chain fatty acids, short chain triglycerides, medium chain fatty acids, medium chain triglycerides, long chain fatty acids, long chain triglycerides, berberine, metabolites of berberine (e.g., dihydroberberine), and/or combinations thereof..
Nanoparticles for controlled lysis of blood clots
Fibrinolytic nanoparticles including a polymeric core having a surface that is functionalized with a cationic amphiphilic compound, and a fibrinolytic agent dispersed within the core, are described herein. The fibrinolytic nanoparticles can be used in method of dissolving a blood clot in a subject by administering to the subject a therapeutically effective amount of fibrinolytic nanoparticles..
Treatments for blood sugar levels and muscle tissue optimization using extracorporeal acoustic shock waves
A method of treating red blood cells of a human patient has the steps of activating an acoustic shock wave generator or source to emit acoustic shock waves and subjecting a vascular system containing red blood cells and surrounding muscle tissue peripherally through an extremity of a patient to the acoustic shock waves by stimulating the extremity wherein the extremity is positioned within a path of the emitted shock waves and away from a geometric focal volume or point of the emitted shock waves. The methods also treat muscle tissue of aging patients, from muscle regeneration or athletes for legal performance enhancement without drugs..
A plaque tack can be used for holding plaque against blood vessel walls such as in treating atherosclerotic occlusive disease. The plaque tack can be formed as a thin, annular band for holding loose plaque under a spring or other expansion force against a blood vessel wall.
System and locating and identifying the functional nerves innervating the wall of arteries and catheters for same
System and method for locating and identifying nerves innervating the wall of arteries such as the renal artery are disclosed. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve.
Ablation catheter device
An ablation catheter device (100) comprises a hollow catheter main body (102), an ablation mechanism (103) and a control mechanism. The ablation mechanism (103) comprises a support assembly (110) capable of being expanded and compressed radially, an end (120) and a plurality of modulation units.
Pulmonary-vein cork device with ablation guiding trench
A method includes inserting into a patient body a catheter, which includes an insertion tube and at least an expandable distal-end device coupled to a distal end of the insertion tube. The distal-end device is expanded in a blood vessel, thereby forming an annular guiding trench between the distal-end device and a circumference of the blood vessel, the annular trench shaped to receive and guide a distal tip of a medical instrument.
Tissue-removing catheter with adjustment mechanism
A tissue removing catheter includes an apposition mechanism that selectively imparts an axially compressive load on the catheter body to bend the catheter and urge a tissue-removing element toward a blood vessel wall. The apposition mechanism can include one or more adjustment lines and an adjustment mechanism for selectively tensioning one of the adjustment lines to impart the compressive load on the catheter body.
Snap link-type surgical clip
A surgical clip includes a first clamping leg and a second clamping leg, the two clamping legs, when in use, being movable towards each other such that they squeeze a blood vessel shut and are linked to each other via a connecting piece which applies a closing force forcing the two clamping jaws towards each other, with two additional springs being provided in addition to the connecting piece which functions as the main spring and amplifying the closing force, the additional springs being arranged in parallel to the main spring and acting in opposite directions.. .
Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery.
Surgical instrument with detection sensors
Aspects of the present disclosure are presented for a surgical instrument having one or more sensors at or a near an end effector and configured to aide in the detection of tissues and other materials and structures at a surgical site. The detections may then be used to aide in the placement of the end effector and to confirm which objects to operate on, or alternatively, to avoid.
Surgical retraction device
A surgical appliance includes a pair of opposed prongs slideably disposed on an elongated locking track for retracting neurovascular and musculotendinous anatomical structures through an incision for affording access to deeper structures for inserting osteosynthesis hardware in the surgical treatment of a distal radius fracture or other surgical procedure. The prongs extend from retractors that traverse the locking track for opposed linear movement while recessed in a surgical working region accessible through an incision.
Devices and methods for measuring vascular deficiency
The present invention relates to devices and methods for measuring vascular deficiency using doppler ultrasound detection. Embodiments can be used to monitor the condition of surgical tissue flaps or other conditions in which obstruction in the vascular system can impact patient health.
Device to hold multiple blood pressure reading units with position indicator
A device to hold multiple blood pressure reading units with position indicator has a blood pressure monitor holder with a shelf portion holding multiple blood pressure monitors. The holder is moveably attached using a position indicator attached to the patient using a collar.
Blood pressure cuff with tapered bladder
A blood pressure cuff may comprise an alignment component, a sleeve, and a tapered inflatable bladder disposed within the sleeve. The tapered inflatable bladder may have a width that increases as the distance from the alignment component increases, and the tapered inflatable bladder and the alignment component may be configured to position the blood pressure cuff around a limb having a blood vessel and a circumference, such that at a position coincident with the blood vessel, the width of the tapered inflatable bladder is about 40% of the circumference of the limb.