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 Intelligent blood pressure monitoring patent thumbnailIntelligent blood pressure monitoring
In some implementations, a user device can assist a user with intelligent blood pressure monitoring. For example, the user device can present notifications and/or reminders that prompt the user to take blood pressure measurements at a prescribed time or according to a prescribed schedule.
Apple Inc.


 Detection of restensosis risk in patients receiving a stent patent thumbnailDetection of restensosis risk in patients receiving a stent
Provided is a method of selecting a stent for implantation in the circulatory system of a human being. The method comprises obtaining a blood sample from a patient who requires implantation of a stent and testing said blood sample to determine a platelet coagulability level.

 Apparatus for monitoring blood coagulation patent thumbnailApparatus for monitoring blood coagulation
There is disclosed an apparatus is disclosed for monitoring blood coagulation comprising a main body; a test chamber for receiving a fluid sample; and a rotor disposed within the test chamber. The rotor comprises a buoyancy chamber for reducing the apparent weight of the rotor when fluid is positioned within the test chamber..
Benson Viscometers Ltd.


 Fgf2 truncations and mutants and uses thereof patent thumbnailFgf2 truncations and mutants and uses thereof
The present disclosure provides fgf2 mutant proteins, such as those having an n-terminal deletion, point mutation(s), or combinations thereof, which can reduce blood glucose in a mammal. Thus, the disclosed mutant fgf2 proteins can be used to treat one or more metabolic diseases.
Salk Institute For Biological Studies


 A  generating a monitoring signal using a supervising entity or safety module patent thumbnailA generating a monitoring signal using a supervising entity or safety module
The present invention relates to method for generating a monitoring signal by monitoring laboratory values of a patient using a medical app (122). The medical app (122) is executed on a mobile device (102) of the patient, wherein the execution of the medical app (122) on the mobile device (102) of the patient is supervised by a supervising entity or safety module (106, 128), the supervising entity or safety module (106, 128) comprising at least executable program instructions (130).
Roche Diabetes Care, Inc.


 Heart assist device with expandable impeller pump patent thumbnailHeart assist device with expandable impeller pump
An impeller includes a hub and a blade supported by the hub. The impeller has a stored configuration in which the blade is compressed so that its distal end moves towards the hub, and a deployed configuration in which the blade extends away from the hub.
Tc1 Llc


 Stable micelle and/or liposome compositions and uses thereof patent thumbnailStable micelle and/or liposome compositions and uses thereof
Pharmaceutical compositions comprising stabilized self-assembling amphiphilic molecular structure (sams) having average diameters of 120 nm or less with a low zeta potential of less than 30 mv to be used for total parenteral nutrition (tpn) or total parenteral alimentation (tpa), increase blood pressure, renal dialysis, transport and release hydrophobic gases, exchange transfusion to replace blood, extracorporeal membrane oxygenation (ecmo), open constricted or blocked blood vessels, treat septic shock and irreversible shock due to sepsis and/or severe blood loss irreversible septic shock, treat dilutional coagulopathy of severe blood loss and bleeding with loss of clotting factors, and replace lost volume in childhood diseases that cause hypovolemia or severe hypovolemia, treat traumatic brain injury, burns, diagnosis of diseases and methods of making and using said compositions.. .
Vivacelle Bio, Inc.


 Endovascular method and apparatus with electrical feedback patent thumbnailEndovascular method and apparatus with electrical feedback
An apparatus for delivering energy, and in particular laser energy, to a tissue is adapted to minimize or eliminate burn back caused by contact between the energy delivery apparatus and bodily fluids by (i) preventing the energy delivery apparatus from contacting bodily fluids or tissues that might burn or cause the apparatus to burn; and/or (ii) monitoring the apparatus to detect overheating in order to withdraw the apparatus or control the energy supply in case overheating is detected. The apparatus is applicable, by way of example, to treatment of blood vessels using endovascular techniques..

 Atherectomy devices and methods patent thumbnailAtherectomy devices and methods
Rotational atherectomy devices and systems can remove or reduce stenotic lesions in blood vessels by rotating an abrasive element within the vessel. The abrasive element can be attached to a distal portion of an elongate flexible drive shaft that extends from a handle assembly.
Cardio Flow, Inc.


 Puncture range determination apparatus and method patent thumbnailPuncture range determination apparatus and method
Provided are a puncture range determination apparatus and a puncture range determination method in which the hardness of tissue is considered as well as blood vessels. A blood vessel (32) is detected through performing doppler processing.
Fujifilm Corporation


Flexible medical device with marker band and sensor

A system and method for determining a ph level of blood in a vessel of a patient including a flexible elongated device configured and dimensioned for insertion in the vessel of the patient. The elongated device has a tubular portion, a marker band positioned distally of the tubular portion and a ph sensor positioned within the marker band to measure the ph level of blood downstream of the blood clot and an indicator to indicate the measured ph..
Makaha Medical, Llc.

Medical image processing apparatus, medical image diagnosis apparatus and recording medium

According to the embodiments, a medical image diagnosis apparatus includes a memory and processing circuitry. The memory stores volume data on a target portion including a vessel network and a plurality of blood vessels connected to the vessel network.
Toshiba Medical Systems Corporation

Non-invasive blood pressure monitor, a operating the same, and a computer program implementing said method

According to an aspect there is provided a method of obtaining a measurement of the blood pressure of a subject using a non-invasive blood pressure, nibp, monitor and including using a pulse rate sensor and a cuff that is to be placed around a limb of the subject, the method comprising using the pulse rate sensor to obtain information on the pulse rate of the subject; adapting a pressure signal filter according to the obtained information on the pulse rate of the subject; starting inflation of the cuff; obtaining a pressure signal representing the pressure in the cuff as the cuff is inflated; filtering the pressure signal using the adapted pressure signal filter during inflation of the cuff; and processing the filtered pressure signal to obtain a blood pressure measurement for the subject during inflation of the cuff.. .
Koninklijke Philips N.v.

Blood pressure measuring auxiliary device and blood pressure measuring apparatus, and design method therefor

A blood pressure measuring auxiliary device, a blood pressure measuring apparatus and a design method therefor are provided. During a blood pressure measurement, the measured pressure values and beating sound are recorded, so that the recorded pressure values and sound may be played back, which improves the accuracy of the auscultatory method; and the parameters used in the oscillometric method may be adjusted, which improves the accuracy of the oscillometric method.

Systems and methods for assessing vasculature health and blood clots

A system and method for determining a ph level of blood in a vessel of a patient including a flexible elongated member configured and dimensioned for insertion in the vessel of the patient, a sensor positioned at the distal portion of the elongated member, and a connector connecting the elongated member to an indicator. The sensor measures the ph level of blood downstream of the blood clot.
Makaha Medical, Llc.

Method for determining collateral information describingthe blood flow in collaterals, medical imaging device, computer program and electronically readable data medium

Determining collateral information describing blood flow in collaterals of a blood vessel system in a target region of a patient from a four-dimensional vascular data set describing image values of temporal flow of a contrast medium and/or marked blood constituents as recorded by a medical imaging device is provided. A method includes segmenting the blood vessel system in the vascular data set and determining collaterals among the segmented blood vessels by a collateral classifier.

Methods of obtaining 3d retinal blood vessel geometry from optical coherent tomography images and methods of analyzing same

Embodiments relate to extracting blood vessel geometry from one or more optical coherent tomography (oct) images for use in analyzing biological structures for diagnostic and therapeutic applications for diseases that can be detected by vascular changes in the retina. An oct image refers generally to one or more images of any dimension obtained using any one or combination of oct techniques.
Bio-tree Systems, Inc.

Method for determining patient-specific blood vessel information

The present invention relates to a method for determining patient-specific blood vessel information. More specifically, the present invention relates to a method for determining patient-specific cardiovascular information by applying a simplified coronary circulation model thereto.
Knu-industry Cooperation Foundation

Spoof detection by ultrasonic subdermal probe

Methods and systems of determining whether an object is alive, and therefore part of a live individual, are described. An object having an outer surface (e.g.
Qualcomm Incorporated

Method for measurement of peptidic degradation products of a proteolytic cascade in blood samples

The invention discloses a method for measurement of peptidic degradation products of a proteolytic cascade in biological samples, especially blood samples, wherein the sample is incubated until a steady state equilibrium is reached for at least one peptidic degradation product involved in said proteolytic cascade and wherein said at least one peptidic degradation product in steady state equilibrium of the proteolytic cascade is quantified in the sample.. .
Attoquant Diagnostics Gmbh

Circulating tumor cell diagnostics for identification of resistance to androgen receptor targeted therapies

The disclosure provides a method of predicting de novo resistance to androgen receptor (ar) targeted therapy in a tumor of a prostate cancer patient comprising (a) performing a direct analysis comprising immunofluorescent staining and morphological characteristization of nucleated cells in a blood sample obtained from the patient to generate circulating tumor cell (ctc) data, wherein the analysis comprises determining a measurable feature of a panel of traditional and non-traditional ctc biomarkers for de novo resistance to androgen receptor (ar) targeted therapy, and (b) evaluating the ctc data to determine the probability of de novo resistance to the ar targeted therapy in the tumor of the prostate cancer patient. Further disclosed are the panel of traditional and non-traditional ctc biomarkers for the methods..
Epic Sciences, Inc.

Methods of diagnosing proliferative disorders

The present invention relates to methods of diagnosing and/or prognosing proliferative disorders, especially brain cancers (e.g. Gliomas).
University Of Central Lancashire

Reagents and methods for detecting pnh type ii white blood cells and their identification as risk factors for thrombotic disorders

The disclosure relates to methods for detecting pnh type ii cell populations in biological samples as well as methods for determining whether a patient is at an increased risk for developing thrombocytopenia or thrombosis based on the percentage of pnh type ii cells in the patient's blood. The disclosure also features reagents and conjugates for use in the methods..
Alexion Pharmaceuticals, Inc.

Flexible biological fluid filters

Filter assemblies are processing biological fluid, such as blood or a blood component containing leukocytes. The filter assemblies include a flexible housing with first and second walls.
Fenwal, Inc.

Localized treatment of tissues through transcatheter delivery of active agents

Embodiments herein include catheters and methods for the localized treatment of tissues through transcatheter delivery of active agents. In an embodiment, a method herein can include inserting a catheter into the lumen of a blood vessel.
Surmodics, Inc.

Delivery system for active agent coated balloon

Embodiments herein include delivery systems for active agent coated balloons and related methods. In an embodiment, a delivery system can include a tunneling sheath and a balloon catheter.
Surmodics, Inc.

Regulating entry into a closed-loop operating mode of an insulin infusion system

An electronic controller for an insulin infusion device includes at least one processor device and at least one memory element that cooperate to provide a processor-implemented closed-loop initiation module. The initiation module is operated to obtain a most recent calibration factor for a continuous glucose sensor, the most recent calibration factor representing a first conversion value applicable to convert a first sensor value to a first blood glucose value.
Medtronic Minimed, Inc.

Chelator-targeting ligand conjugates for cardiovascular imaging

Disclosed are methods of imaging a site in a heart of a subject to detect cardiovascular disease that involve stressing a subject, administering to the stressed subject an effective amount of a radionuclide-labeled chelator-glucose analog conjugate, and imaging the heart of the subject by detecting a signal generated by the conjugate in the heart of the subject. Also disclosed are methods of imaging a peripheral blood vessel in a subject by using a detectable amount of a radionuclide-labeled chelator-glucose analog conjugate.
Cell>point, Llc

Method for preparing universal plasma

The present invention relates to an universal plasma, originating from a mixture of plasmas originating from donor individuals of blood groups a, b, ab and/or o and compatible with all the blood groups and the preparation process thereof.. .
Laboratoire Francais Du Fractionnement Et Des Biotechnologies

Use of nitrite salts for the treatment of cardiovascular conditions

It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial, for example, to tissues in regions of low oxygen tension.
Wake Forest University

Non-anticoagulant sulfated or sulfonated synthetic polymers

The present invention provides pharmaceutical formulations including a non-anticoagulant, non-saccharide polymer that with at least one sulfate or sulfonate moiety. The pharmaceutical formulations of the invention are of use to improve blood clotting in a subject.
Baxalta Gmbh

Erythrocyte function improving agent

An object of the present invention is to provide an agent for improving red blood cell function which has both high antioxidant action and high ability to migrate into red blood cells, and can effectively protect red blood cells against oxidative stress. Cucurbitaxanthin a and/or a derivative thereof has an ability to migrate into red blood cells significantly higher than that of the other carotenoids reported to migrate into red blood cells, and can effectively protect red blood cells against oxidative stress, and thus, is effective as an agent for improving red blood cell function..
Glico Nutrition Co., Ltd.

Methods & systems to determine multi-parameter managed alarm hierarchy during patient monitoring

The present specification discloses systems and methods of patient monitoring in which multiple sensors are used to detect physiological parameters and the data from those sensors are correlated to determine if an alarm should, or should not, be issued, thereby resulting in more precise alarms and fewer false alarms. Electrocardiogram readings can be combined with invasive blood pressure, non-invasive blood pressure, and/or pulse oximetry measurements to provide a more accurate picture of pulse activity and patient respiration.
Spacelabs Healthcare Llc

Surgical resection apparatus

Surgical cutting apparatus having a treatment channel and a measurement channel for conveying microwave energy from a source to an antenna at a cutting edge. The measurement channel operates at lower power than the treatment channel for determining when higher energy can be safely applied.
Creo Medical Limited

Methods and medical elongate bodies

A method and a medical elongate body are configured to prevent stagnation or turbulence of blood flow in a recess of a rugged pattern formed in a blood vessel due to bulging of a blood vessel wall at a lesion part of the blood vessel. The method involves partitioning an inside of the blood vessel into upstream and downstream sides of the recess, and introducing gel into the recess to at least partially fill the recess.
Terumo Kabushiki Kaisha

Method and accelerated disintegration of blood clot

Systems and methods for treating a blood clot include a catheter to be inserted into a patient. The catheter is used to deliver low stability microbubbles toward the blood clot in the patient.
University Of Virginia Patent Foundation

Insulin management

A method of managing insulin includes receiving blood glucose measurements on a computing device from a glucometer. The blood glucose measurements are separated by a time interval.
Aseko, Inc.

Measurement device and measuring psychology stress index and blood pressure

A measurement device and method for measuring psychology stress index and blood pressure is disclosed. When the measurement device is in the psychology stress measurement mode and a pressurizing motor unit is pressurizing an airbag unit with a variable speed, the micro-processor unit may control the pressurizing motor unit to stop pressurizing the airbag unit after the pressure signal is determined as a pulse signal, and the micro-processor unit may measure the pulse signal to determine the psychology stress index.
Avita Corporation

Sleep state monitoring system based on pulse wave measurement

A sleep state monitoring system is provided a pressure sensor, an optical sensor, and a controller. The pressure sensor detects a change in pressure of a pulse wave propagating through a blood vessel to measure a voltage value as a first voltage value of arterial pressure, and the optical sensor detects a change in pressure of a pulse wave propagating through the blood vessel by use of an optical signal to measure a voltage value as a second voltage value of a vascular pulse wave signal.
Act Medical Service Co., Ltd.

Methods and devices for analyte sensing in potential spaces

Use of the peritoneal space provides a more direct tracking of blood glucose, capturing faster glucose kinetics, avoiding membrane/encapsulation effects, having less lag time and lag time variability, and eliminating the effect of variations in skin temperature, cardiac output, and body position during sleep. A peritoneal sensor system may be implanted within the peritoneal space and may generally include a sensor/sampler portion, which is implanted in the peritoneal space, and a control portion/controller, which may be implanted elsewhere, such as subcutaneously, or may be external to the patient..

Wrist worn accelerometer for pulse transit time (ptt) measurements of blood pressure

Wrist-worn devices and related methods measure a pulse transit time non-invasively and calculate a blood pressure value using the pulse transit time. A wrist-worn device includes an accelerometer, a photo-plethysmogram (ppg) or a pulse pressure sensor, and a controller.
Apple, Inc.

System for predicting risk of onset of cerebrovascular disease

Attempts have been made in the past to predict the risk of onset of a disease from biological information, but, in practical terms, it is difficult to continuously acquire biological information on a regular basis, and there is no increase in the accuracy of predicting variations in the risk of onset of a disease based only on the acquired biological information. A compact pulse wave information acquisition element is fitted to a measurement subject, information is continuously acquired on a regular basis, and the risk of onset of cerebrovascular disease is predicted from fluctuations in blood pressure and pulse waveform on the basis of the pulse wave information continuously acquired on a regular basis..
Shinano Kenshi Co., Ltd.

Precise estimation of glomerular filtration rate from multiple biomarkers

The present invention relates to the field of nephrology. More specifically, the present invention provides methods and compositions useful for more precisely estimating glomerular filtration rate (gfr).
Tufts Medical Center, Inc.

Steap3 as a biochemical marker of red blood cell storage and toxicity

Compositions and methods for determining post-transfusion survival or toxicity of red blood cells and the suitability of red blood cell units for transfusion by measuring the levels of one or more markers in a red blood cell sample are provided.. .
Bloodworks

Electrical characteristic measuring device and program

To an electrical characteristic measuring device that further improves the accuracy of measurement of an electrical characteristic of a blood sample. Provided is an electrical characteristic measuring device including: a measuring unit configured to measure an electrical characteristic of a blood sample; and an alert generation unit configured to issue an alert signal when an erythrocyte sedimentation rate in the blood sample exceeds a prescribed standard during measurement of the blood sample..
Sony Corporation

Method for discriminating red blood cells from white blood cells by using forward scattering from a laser in an automated hematology analyzer

A method for identifying, analyzing, and quantifying the cellular components of whole blood by means of an automated hematology analyzer and the detection of the light scattered, absorbed, and fluorescently emitted by each cell. More particularly, the aforementioned method involves identifying, analyzing, and quantifying the cellular components of whole blood by means of a light source having a wavelength ranging from about 400 nm to about 450 nm and multiple in-flow optical measurements and staining without the need for lysing red blood cells..
Abbott Laboratories

Apparatus and extracting microbial cells

Methods and devices are provided for pre-treatment of a sample containing microbial cells. In some embodiments, the pre-treatment of the sample is performed via the initial selective lysis, within a sample pre-treatment vessel, of non-microbial cells, such as blood cells, and the subsequent centrifugal separation of the sample to remove the resulting debris and concentrate the microbial cells.
Qvella Corporation

Cannula with light-emitting optical fiber

A catheter device to visually identify a blood vessel may include a cannula. The cannula may include a distal tip, an elongated tubular shaft, and an inner lumen formed by the elongated tubular shaft.
Becton, Dickinson And Company

Apparatus and sterilizing blood

A method and apparatus to neutralize or destroy pathogens in red blood cell concentrate (rbcc). The apparatus may include a lamp to provide ultra-violet (uv) light having a predetermined wavelength, a focusing member to focus the uv light from the lamp, a chamber assembly to receive the rbcc at a predetermined flow rate and to cause the received rbcc to be exposed to the focused uv light, and a controller.

Methods for increasing red blood cell levels and treating ineffective erythropoiesis

In certain aspects, the present disclosure provides compositions and methods for increasing red blood cell and/or hemoglobin levels in a subject in need thereof. Subjects in need include, for example, subjects having anemia and/or ineffective erythropoiesis as a result of having reduced gata-1, heat shock factor and/or nfe2 levels as compared to the levels in a reference population..
Acceleron Pharma Inc.

Sugar compositions for treating hemophilia a and/or von willebrand disease

The invention relates to compositions comprising an isolated sugar for use in the treatment of von willebrand disease and/or hemophilia a, wherein the sugar is an accessible sugar residue derived from abo(h) blood group antigen.. .
Csl Behring Gmbh

Method for preparing a biological tissue construct and use of autologous cells obtained specifically

The method for preparing a tissue construct for medical purposes uses endothelial progenitor cells (epc) which have not been passaged multiple times and have a content of eoec (early outgrowth endothelial progenitor cells) and loec (late outgrowth endothelial progenitor cells). These cells and fibroblasts and/or muscle cells, viz.
Medizinische Hochschule Hannover (mhh)

Platelet rich plasma formulations and use thereof

Compositions for platelet rich plasma (prp) are provided. Generally, these compositions comprise a higher concentration of platelets than whole blood.

Compositions and methods for increasing red blood cells

The invention relates generally to a composition and method for increasing the frequency, amount, or presence of red blood cells in peripheral blood. In one embodiment, the invention comprises the inhibition of, or genetic modification of the genes encoding, one or more scavenger receptors.
Yale University

Devices and methods for controlling blood perfusion pressure along with regional mild hypothermia

Methods and devices for controlling blood perfusion pressure along with regional mild hypothermia. In at least one embodiment of a device for controlling blood perfusion pressure within a vessel of the present disclosure, the device comprises an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure, a partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel and to equalize the first blood pressure at the first area with the second blood pressure at the second area, and a regional hypothermia system operably coupled thereto, the regional hypothermia system operable to reduce and/or regulate a temperature of a bodily fluid flowing therethrough..
Cvdevices, Llc

Controlled irrigated catheter ablation systems and methods thereof

The present invention relates to open irrigated catheter ablation systems and methods used in connection with open irrigated catheter systems. The systems and related methods can control irrigation fluid flow to obtain temperature responses indicative of temperatures associated with an ablation procedure.
St. Jude Medical, Atrial Fibrillation Division, Inc.

Arthroendoscopical surgical method

An arthroscopical surgical method using an ultrasonic treatment device for a joint includes: transmitting ultrasonic vibration to a treatment portion of the ultrasonic treatment device, removing an injured region of an articular cartilage so that a subchondral bone is exposed, and forming a cartilage edge which is nearly angled at 90° with the exposed surface of the subchondral bone to form a pool-shaped depression; forming a hole which pierces up to a cancellous bone of the subchondral bone through the depression, and scratching blood vessels in the cancellous bone; causing bleeding from the blood vessels so that blood is retained in the depression via the hole.. .
Olympus Corporation

Thin wall constructions for vascular flow diversion

Devices that can be delivered into a vascular system to divert flow are disclosed herein. According to some embodiments, devices are provided for treating aneurysms by diverting flow.
Covidien Lp

Methods and systems for endovascularly clipping and repairing lumen and tissue defects

An implantable closure structure is delivered using minimally invasive techniques, and inhibits the migration of liquid and particulate matter from inside a physiological cavity or opening, such as an aneurysm or a septal defect, as well as inhibiting the flow of liquid and particulate matter, such as from an associated blood vessel or chamber, into the physiological cavity or opening. The device has a closure structure that covers the neck or opening of a cavity and has one or more anchoring structures for supporting and retaining the closure structure in place across the cavity or opening..
Pulsar Vascular, Inc.

Acoustic streaming for fluid pool detection and identification

Ultrasound-based acoustic streaming for deciding whether material is fluid is dependent upon any one or more of a variety of criteria. Examples are displacement, speed (230), temporal or spatial flow variance, progressive decorrelation, slope or straightness of accumulated signal to background comparisons over time, and relative displacement to adjacent soft tissue.
Koninklijke Philips N.v.

Method and image data system for generating a combined contrast medium and blood vessel representation of breast tissue to be examined, computer program product and computer-readable medium

A method for generating a combined contrast medium and blood vessel representation of contrast-enhanced image data of breast tissue to be examined includes capturing first and second contrast-medium-influenced x-ray projection measurement data of the breast tissue with respective differing first and second x-ray energies. First and second image data sets are reconstructed based respectively on the first and second measurement data.
Siemens Healthcare Gmbh

Image processing method and apparatus, and program

In displaying a tomographic image in a slice in a three-dimensional (3d) medical image, for the purpose of achieving better recognition of a vascular structure contained in the slice without degrading spatial resolution of the slice, there is provided an image processing apparatus comprising: identifying section for identifying a slice of interest in a 3d medical image representing an anatomical part including a blood vessel; and projecting section for applying projection processing to pixel values in a slice axis direction of the slice for a region in the 3d medical image including the slice and wider than a slice width of the slice.. .
General Electric Company

Method and heart rate and respiration rate estimation using low power sensor

Provided is a system for measuring biological signals of a user, which includes a sensor module configured to acquire ballistocardiogram (bcg) signals of a user via a present channel, where the present channel is at least one channel of the sensor module, a decomposition module configured to decompose the bcg signals to decomposed signals, a reconstruction module configured to reconstruct at least a portion of the decomposed signals to reconstructed signals, a processing module configured to process the reconstructed signals to at least one of a heart rate, respiration rate, phases of respiration, and blood pressure, and a display module configured to display at least one output corresponding to the at least one of the heart rate, the respiration rate, phases of respiration, and the blood pressure on a display device.. .
Samsung Electronics Co., Ltd.

Blood pressure measurement device and blood pressure measurement

A blood pressure measurement device comprises a case, a first electrode and a stress sensor. The case includes a first surface and a second surface.
Maisense Inc.

Blood pressure estimation apparatus, sphygmomanometer, blood pressure estimation system, and blood pressure estimation method

Provided are a blood pressure estimation apparatus, a sphygmomanometer, a blood pressure estimation system, and a blood pressure estimation method which allow continuous blood pressure measurement without adding stress to a subject's body. A plurality of sensors and a controller are included.
Kyocera Corporation

Method and fractional flow reserve measurements

A method of determining fractional flow reserve (ffr) in a blood vessel having stenosis includes injecting fluid into the blood vessel upstream of the stenosis using a power fluid injector, measuring pressure drop across the stenosis, and calculating ffr from measured pressure drop. The injected fluid may comprise a contrast medium.
Bayer Health Care Llc

Automatic analyzer

A high-throughput automatic analyzer integrates a biochemical analysis section and a blood coagulation analysis section. The analyzer is capable of achieving a reduction in size, system cost, and lifecycle cost.
Hitachi High-technologies Corporation

Methods for differentiating ischemic stroke from hemorrhagic stroke

The invention relates to a method for differentiating ischemic stroke from hemorrhagic stroke in a patient and to a method for selecting a patient suffering stroke for a therapy with an antithrombotic agent or with an agent capable of reducing blood pressure based on the determination of the level of gfap in a sample of said patient in combination with one or more markers selected from the group consisting of nef3, β-synuclein, carns1 and rbp4, or based on determining the level of rbp4 in a sample of said patient. Furthermore, the invention relates to a kit comprising a reagent for detecting the level of a marker selected from gfap nef3, β-synuclein, carns1, rbp4 or a combination thereof and to the use of the said kit in the methods of the invention..
Fundacio' Hospital Universitari Vall D'hebron- Institut De Recerca

Assessment of heart failure and arrhythmic risk stratification by measuring circulating hu proteins

This invention relates to a diagnostic test measuring circulating hu proteins or gene transcripts in a blood sample to assess arrhythmic risk in heart failure patients. The invention addresses this need and features a diagnostic/prognostic test for measuring circulating hu levels in a sample to assess arrhythmic risk in heart failure patients, alternatively, to determine the risk of scd.
Rhode Island Hospital

Method for capturing rare cells in blood

A method for capturing rare cells in blood includes isolating rare cells in blood from blood, the method including a step of removing white blood cells from the blood before blood filtration using a filter.. .

Method for flagging a sample

A hematology analyzer is provided. In certain embodiments, the hematology analyzer comprises: a) a flow cell; b) a light source for directing light to the flow cell; c) a plurality of detectors for detecting a plurality of optical characteristics of a blood cell passing through the flow cell; and d) a data analysis workstation programmed to: i.
Abbott Laboratories

Methods of making a test sensor

A sensor, and methods of making, for determining the concentration of an analyte, such as glucose, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and may include an insertion monitoring trace to determine correct positioning of the sensor in a connector.
Abbott Diabetes Care Inc.

Method for capturing rare cells in blood

A method for capturing rare cells in blood includes isolating rare cells in blood from blood, the method including a step of removing white blood cells from the blood after blood filtration using a filter.. .

Automatic monitoring cell culture growth

In the automated method according to the invention for monitoring cell culture growth, in particular bacterial growth, a receiving dish (24) with a nutrient medium (38) is provided onto and/or into which is applied a cell culture, in particular a sample of human or animal tissue, such as blood, to which bacteria have been added and which also contains one or a plurality of reagents, in particular antibiotics. A microscope (10) having a camera (18) and an image acquisition plane adapted to be moved along the optical axis (20) is provided, and the receiving dish (24) is brought into the microscope (10) for monitoring a potential growth of the cell culture in the nutrient medium (38).
Fraunhofer-gesallschaft Zur Förderung Der Angewandten Forschung E.v.

Tumor vascular disrupting agent polypeptide, gene, expression vector, and use thereof

The present invention relates to a tumor vascular disrupting agent polypeptide, gene, expression vector, and use thereof. The tumor vascular disrupting agent polypeptide has the amino acid sequence as shown by seq id no: 1.
Beijing Hua'an Innovation Biotechnology Co., Ltd.

Apparatus and promoting angiogenesis in ischemic tissue

A biologics delivery device and method of use for promoting angiogenesis in occluded vessels and ischemic tissue of a patient are provided, wherein the biologics delivery device includes a catheter having a proximal end, a distal region having a distal end, and a side wall defining a catheter lumen; an expandable member disposed in the distal region, the expandable member configured to support a subintimal space in an occluded blood vessel of a patient, and to transition between a collapsed state and an expanded state; and a hollow needle having a penetration tip deployable from inside the catheter lumen to outside the catheter lumen, and into tissue surrounding the occluded blood vessel, wherein the expandable member in the expanded state allows the flow of oxygenated blood to the occluded blood vessel. Methods of using the inventive biologics delivery device also are provided to deposit the biologic from a subintimal space to tissue surrounding the occluded blood vessel..

Indwelling assembly

An indwelling assembly includes an inner needle having a sharp needlepoint, an inner needle hub fixed to the inner needle, a hollow elongated outer member in which the inner needle is positioned and movable in a distal direction relative to the inner needle after puncturing the blood vessel to position the elongated outer member at a desired position in the blood vessel, an outer member hub fixed to hollow elongated outer member, a projection removably connected to the outer member hub and configured to be engaged by a finger of the user to apply a force to the projection causing the outer member hub and the hollow elongated outer member to move together with the projection in the distal direction relative to the inner needle and the inner needle hub, and an elongated movable member that is movable relative to the hollow elongated outer member and the outer member hub.. .
Terumo Kabushiki Kaisha

Anthracenyl-tetralactam macrocycles and their use in detecting a target saccharide

Wherein r9 and r10 are suitably hydrophilic substituents, which may be used to selectively bind to a target saccharide such as glucose and which exhibits a detectable spectroscopic response to such binding, thus enabling its use in the detection and correction of blood glucose concentrations in vivo.. .

Compositions and methods for producing elevated and sustained ketosis

Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of (2-7 mmol/l), with or without dietary restriction. The combination results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance in a short period of time.
University Of South Florida

Local administration-type pharmaceutical for improving dysphagia

A dysphagia improving composition characterized in that a substance having an inhibitory action on an angiotensin converting enzyme, which is a degrading enzyme of substance p, is administered locally in a dosage not influencing blood pressure, and a pharmaceutical for improving dysphagia containing the composition.. .
Meiji Seika Pharma Co., Ltd.

Blood vessel dissection device and blood vessel dissection method

A blood vessel dissecting device is disclosed, which includes a dissecting device configured to be inserted into a living body along a blood vessel to dissect tissue surrounding the vessel from tissue surrounding the vessel in a direction along a longitudinal extent of the blood vessel; and a cutting device configured to fee inserted into the living body along the longitudinal extent of the blood vessel to cut the tissue surrounding the blood vessel so the direction of longitudinal extent of the blood vessel.. .
Terumo Kabushiki Kaisha

Electro-cauterizing bi-polar surgical forceps

A bi-polar forceps for providing electro-cauterization of tissue and blood vessels including first and second elongated beams extending from a rearmost interconnected end to forward most separated probe ends. The beams each include rearmost base portions, intermediate angled portions and forward most extending portions such that the probe ends are established in a non-linear arrangement relative to the rearmost portions.

Methods and devices for cutting and abrading tissue

The present invention provides an atherectomy catheter which has a cutting element that is able to cut both soft tissue and hard tissue, and methods of cutting material from a blood vessel lumen using a rotating cutting element. The cutting element has a sharp cutting edge that surrounds a cup-shaped surface and at least one surface of abrasive material.
Covidien Lp

Ultrasound catheter and methods for making and using same

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen.
Flowcardia, Inc.

Vascular closure device

The present disclosure relates to a vascular closure device adapted for use in closing a puncture in a blood vessel after e.g. A percutaneous interventional procedure.
M-v Arterica Ab

Method for characterisation of perivascular tissue

Methods for volumetric characterisation of perivascular adipose tissue use data collected by computed tomography (ct) scanning. The volumetric characterisation of perivascular adipose tissue allows the inflammatory status of underlying blood vessels to be established by ct scanning.
Oxford University Innovation Limited

Systems and methods for color visualization of ct images

A computed tomography (ct) imaging system includes a ct imaging unit, a display unit and at least one processor. The ct imaging unit includes an x-ray source and a ct detector.
General Electric Company

Diagnosis support apparatus, operating method, and non-transitory computer readable medium

A diagnosis support apparatus for physiological monitoring includes a data acquisition device for obtaining information of a heartbeat waveform of an examinee. An extractor extracts blood pressure fluctuations based on changes of blood pressure of the examinee from the heartbeat waveform.
Fujifilm Corporation

Blood sample management using open cell foam

A specimen transfer device adapted to receive a blood sample is disclosed. The specimen transfer device includes a housing and an actuation member.
Becton, Dickinson And Company

Iglass: infrared thermography for learning thermoregulation performance

An infrared thermography based technique is described for monitoring an individual's thermoregulation performance and thermal comfort level through measuring the skin temperature on several points the face as the face has a high density of blood vessels and it is typically not covered by clothing. This technique allows for continuous monitoring during normal daily activities and instantaneous identification of thermoregulation performance and thermal comfort.
University Of Southern California

Method and system for recommending a set of insulin dosages for a patient

Disclosed is a method and system for recommending a set of insulin dosages for a patient. The method estimates a blood glucose level of the patient using a physiological glucose-insulin module based on a set of patient-related information.
Quattro Folia Oy

Method and non-contact estimation of pulse transmit time

A method, non-transitory computer readable medium and apparatus for estimating a pulse transmit time (ptt) to calculate a blood pressure are disclosed. For example, the method includes receiving a series of video images over a period of time that includes a first location of an individual and a second location of the individual, calculating a first set of luminance values of the first location and a second set of luminance values of the second location, estimating the ptt based on an average time difference from consecutive peaks of the first set of luminance values and the second set of luminance values and transmitting the ptt to a blood pressure calculation device to calculate the blood pressure based on the ptt that is estimated..
Xerox Corporation

Apparatus for recognizing biometric information and activating a plurality of piezoelectric element individually

The present invention relates to a biological information recognition apparatus and a method for selectively activating, by the biological information recognition apparatus, a plurality of piezoelectric elements. More particularly, the present invention relates to a biological information recognition apparatus which may be used to identify a user by recognizing biological information, such as the fingerprint, blood vessels, and bones of a finger of the user, and a method of driving the same.
Befs Co., Ltd.

Background-suppressed, reduced field-of-view radial magnetic resonance imaging

Embodiments relate to a method and system to improve fat suppression and reduce motion and off-resonance artifacts in magnetic resonance imaging (mri) by using a background-suppressed, reduced field-of-view (fov) radial imaging. The reduction of such artifacts provides improved diagnostic image quality, higher throughput of mri scans for the imaging center, and increased patient comfort.
Northshore University Healthsystem

Multipurpose mass spectrometric assay panels for peptides

Methods are provided for estimating the relative amounts of identifiable compartments, such as different types of cells or cell components, within a biological sample. The methods use mass spectrometric analysis to quantitate compartment-specific molecules and thereby allow calculation of the amount of each compartment that is present in a biological sample.
Siscapa Assay Technologies, Inc.

Protein and autoantibody biomarkers for the diagnosis and treatment of lung cancer

Aspects of the present disclosure include methods of producing a circulating analyte profile of a subject. The methods include contacting a blood sample from a subject with a panel of probes for specific binding to analytes, and detecting the presence or absence of binding of the analytes to probes of the panel of probes.
The Board Of Trustees Of The Leland Stanford Junior University

Calibration and image processing devices, methods, and systems

In part, the invention relates to systems and methods of calibrating a plurality of frames generated with respect to a blood vessel as a result of a pullback of an intravascular imaging probe being pullback through the vessel. A calibration feature disposed in the frames that changes between a subset of the frames can be used to perform calibration.
Lightlab Imaging, Inc.

Preservation of cell-free nucleic acids

A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids..
Streck, Inc.

Spray drier assembly for automated spray drying

A spray drier system is provided for spray drying a liquid sample such as blood plasma. The spray drier system may include a spray drier device adapted to couple with a spray drier assembly.
Velico Medical, Inc.

Axial lengthening thrombus capture system

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (pe), deep vein thrombosis (dvt), cerebrovascular embolism, and other vascular occlusions.. .
Kp Medcure, Inc.

Intravenous catheter insertion and blood sample devices and use

A catheter insertion device includes a housing, a needle, a catheter, and a guide wire. The needle has a proximal end positioned in the housing and a distal end extending beyond a distal end of the housing in a first position.
Vascular Pathways, Inc.

System, method and article for controlling the dispensing of insulin

An integrated circuit includes circuitry to control a process. The process includes adjusting fuzzy-logic control parameters based on received and retrieved blood glucose-related data, predicting blood glucose levels based on the received blood-glucose-related data, and generating control signals to control dispensing of insulin based on the received blood glucose-related data and the fuzzy-logic control parameters.
Dose Safety

Blood pump systems and methods

The present invention relates to a rotary blood pump with a double pivot contact bearing system with an operating range between about 50 ml/min and about 1500 ml/min, wherein the force on the upper bearing is less than 3n during operating speeds up to 6000 rpm. The rotary blood pump is part of a blood pump system that includes blood conduit(s), a control system with optional sensors, and a power source.
Flow Forward Medical, Inc.

Pressure sensing extracorporeal circulation device

An extracorporeal blood circulation system reduces the risk of generation of air bubbles entering the circulation circuit associated with placement of a pressure sensor that detects a patient's blood pressure at a blood removal line. Instead of directly measuring pressure at the blood removal line where suction exists, an intermediate part pressure sensor detects pressure between a centrifugal pump and an oxygenator.
Terumo Kabushiki Kaisha

Corticosteroid formulations and methods for the treatment of joint pain in patients with diabetes

This invention relates to the use of corticosteroids in patients with diabetes, including patients with type 2 diabetes, to treat pain, including pain caused by inflammatory diseases such as osteoarthritis or rheumatoid arthritis without increasing or otherwise significantly impacting blood glucose concentrations in diabetic patients, and to slow, arrest or reverse structural damage to tissues caused by an inflammatory disease, for example damage to articular and/or periarticular tissues caused by osteoarthritis or rheumatoid arthritis without increasing or otherwise impacting blood glucose concentrations. More specifically, a formulation of triamcinolone acetonide (tca) is administered locally to diabetes patients, including type 2 diabetes patients, as a sustained release dosage form (with or without an immediate release component) that results in efficacy levels accompanied by clinically insignificant or no measurable effect on blood glucose levels..
Flexion Therapeutics, Inc.

Blockstent device and methods of use

What is disclosed is a medical device comprising a compressed, cylindrical or oblong, thin-walled, expandable metal structure (a “blockstent”) and a flexible, elongated device (a “delivery catheter”) to position the compressed blockstent into the lumen of a blood vessel segment to be treated, and methods of use for occlusion of treated blood vessel segments. A blockstent can be made with ductile metals such as gold, platinum, or silver such that the blockstent will conform to the shape of the lumen of the treated blood vessel segment during expansion and allow for the shape of the blockstent to be permanently changed by the application of an external force.
Metactive Medical, Inc.

Devices and methods for forming stents in vivo

Materials and methods for generating conformable stents at sites of stenosis in bodily vessels (e.g., blood vessels) are provided herein.. .
Mayo Foundation For Medical Education And Research

Thin-film cuff for endothelialization of endovascular grafts

Methods and devices are provided for the use of thin-film cuffs on endovascular grafts. A method includes forming a fenestrated thin-film nitinol sheet, expanding the fenestrated thin-film nitinol sheet to expand the fenestrations, and attaching the expanded thin-film nitinol sheet to a longitudinal end of a cover for an endovascular graft to form a cuff for the endovascular graft.
Nsvascular, Inc.

Tissue welding and cutting apparatus and method

A surgical apparatus and methods for severing and welding tissue, in particular blood vessels. The apparatus includes an elongated shaft having a pair of relatively movable jaws at a distal end thereof.
Maquet Cardiovascular Llc

Blood vessel treatment method

A blood vessel treatment method including inserting a medical device into a blood vessel, the medical device including an elongate shaft portion and a contact portion configured to contact a biological tissue in the blood vessel; bringing the contact portion into contact with the biological tissue in the blood vessel; twisting the blood vessel by moving the contact portion; and releasing a treatment agent from the medical device for occluding or contracting a lumen of the blood vessel.. .
Terumo Kabushiki Kaisha

Flexible intra-vascular aneurysm treatment stent

An intra-vascular aneurysm-treatment stent and a method for lowering pressure within an aneurysm bubble in a blood vessel. A stent coil is insertable into a blood vessel, the coil made of a material sufficiently flexible to move around curves, loops, and corners in the blood vessel.

Method for acquiring and processing image data of an examination object

A method for acquiring and processing image data of an examination object is provided. A three-dimensional bone model and a three-dimensional blood vessel model are provided.

Diabetes control using postprandial feedback

Disclosed is a postprandial glucose-measuring device for preventing the development of or reversing t2d. Included are methods for using the device as well as better use for invasive and noninvasive glucose meters.

Optimizing analyte sensor calibration

Method and apparatus for optimizing analyte sensor calibration including receiving a current blood glucose measurement, retrieving a time information for an upcoming scheduled calibration event for calibrating an analyte sensor, determining temporal proximity between the current blood glucose measurement and the retrieved time information for the upcoming calibration event, initiating a calibration routine to calibrate the analyte sensor when the determined temporal proximity is within a predetermined time period, and overriding the upcoming scheduled calibration event using the current blood glucose measurement are provided.. .
Abbott Diabetes Care Inc.

Cuff-less multi-sensor system for statistical inference of blood pressure with progressive learning/tuning

In one embodiment of the invention, a cuff-less blood pressure measuring system is disclosed including cuff-less blood pressure scanner with a vital signs signal processor having an adaptive blood pressure model. A machine learning process is further disclosed to tune the adaptive blood pressure model of the cuff-less blood pressure measuring system to the user..
Scanadu Incorporated

Image processor, image processing method, and endoscope system

An image processor calculates diagnosis support parameters on the basis of the state of blood vessels of an observation object. The image processor includes an image acquisition unit that acquires an endoscopic image, a blood vessel extraction unit that extracts blood vessels, using the endoscopic image, a blood vessel information calculation unit, and a blood vessel parameter calculation unit.
Fujifilm Corporation

Rapid screening and evaluation of diabetes and prediabetes by glycated hemoglobin mass spectrometry

The method describes rapid screening of whole blood samples, pin prick and blood spot cards, subjected to maldi-tof mass spectrometry. The spectra is generated and compared to those from normal healthy controls.
Map Ip Holding Limited

Method for measuring concentration of analyte in blood sample, and biosensor system

The method includes: acquiring data a related to a temperature of a blood sample on a sensor chip, based on a dimension of a current flowing in the blood sample by applying a first voltage to the pair of electrodes in contact with the blood sample, the first voltage being set so as to reduce an effect of hematocrit on a temperature measurement result; acquiring data b related to the concentration of an analyte in the blood sample, based on a dimension of a current flowing in the blood sample by applying a second voltage that is equal to or less than the first voltage, utilizing a reaction mediated by an oxidoreductase that uses the analyte in the blood sample as a substrate; and measuring a concentration that determines the analyte concentration in the blood sample based on the data a and the data b.. .
Panasonic Healthcare Holdings Co., Ltd.

Whole blood hemolysis sensor

The present invention pertains to a hemolysis sensor, a hemolysis sensor system and methods of utilizing the hemolysis sensor or hemolysis sensor system to monitor or detect hemolysis in a sample, such as a whole blood sample, a plasma sample, a serum sample or hemolyzed blood. The hemolysis sensor responds to extracellular hemoglobin levels, for example, extracellular hemoglobin in a whole blood sample as a method for detecting hemolysis in whole blood..
Instrumentation Laboratory Company

Methods for treating a disease that develops or progresses as a result of decrease or loss of activity of blood coagulation factor viii and/or activated blood coagulation factor viii

The inventors discovered that by administering a pharmaceutical composition comprising a bispecific antigen-binding molecule that recognizes blood coagulation factor ix and/or activated blood coagulation factor ix and blood coagulation factor x and/or activated blood coagulation factor x according to a given dosage regimen, diseases that develop and/or progress due to a decrease or deficiency in the activity of blood coagulation factor viii and/or activated blood coagulation factor viii can be prevented and/or treated more effectively.. .
Chugai Seiyaku Kabushiki Kaisha

Extended antegrade epicardial coronary infusion of adeno-associated viral vectors for gene therapy

The present invention relates to therapies for the treatment of cardiovascular diseases, particularly the delivery of therapeutic agents to heart tissue by direct infusion into the coronary circulation. A preferred embodiment of the invention is a method of treating or preventing a cardiovascular disease by transfecting cardiac cells of a large mammal, the method comprising, identifying an mammal in need of treatment or prevention of a cardiovascular disease, infusing a therapeutic polynucleotide into a blood vessel of the coronary circulation in vivo, where the therapeutic polynucleotide is infused into the blood vessel over a period of at least about three minutes, where the coronary circulation is not isolated or substantially isolated from the systemic circulation of the mammal; and where the therapeutic polynucleotide transfects cardiac cells of the animal resulting in the treatment or prevention of the cardiovascular disease..
Celladon Corporation

Infusable solution for local treatment of blood vessels and vascular grafts and methods of using such a solution

A novel treatment for dialysis patients needing a hemodialysis graft by providing a therapeutic formulation that can be infused to such patients, which may mitigate graft-related neointimal hyperplasia, thrombosis, and/or related mechanisms of graft failure. The therapeutic formulation may include sirolimus and/or other olimus drug(s).
Cylerus, Inc.

Organic vaccination an alternative method to traditional preventative vaccination

The disclosed method provides an alternative approach of preventative vaccination which consists primarily of extracting and purifying monocytes, naive t and b lymphocytes from a patient and educating said lymphocytes against a pathogen in vitro until a population of antigen-specific memory lymphocytes are created with a memory against an infectious agent. Said memory lymphocytes are administered to a subject in a solution which consist primarily of blood plasma derived from said subject.

Extract of toona sinensis from supercritical fluid extraction for treating diabetes and metabolic disease, the preparation method and the use thereof

The toona sinensis extract of the present invention is prepared using supercritical fluid technique, wherein the method includes steps of: (a) drying the leaves of t. Sinensis; (b) pulverizing the leaves as particles; and (c) extracting the particles with supercritical carbon dioxide to obtain the t.
Kaohsiung Medical University

Beverages for enhancing sexual performance

Described herein are beverages that can enhance sexual performance in both men and women. For example, the beverages are useful in promoting endurance and stamina and in increasing sexual desire as well as blood flow to the genital region.
Hydro One Llc

Systems and methods for intraprocedural evaluation of renal denervation

The present disclosure provides methods, systems, and apparatuses for providing real time intraprocedural operational feedback to the operator as to the success of a renal denervation procedure and its overall effectiveness for reducing the blood pressure of a subject to allow for more precise and thorough ablation of the renal artery and better patient outcomes. Using this real time feedback generated through the electrical stimulation of multiple points about the circumference of the renal artery at specific times during the procedure, the operator can assess the desired procedural endpoint and whether the amount of renal denervation provided to the subject is sufficient, or whether the subject may benefit from further denervation of the renal artery.
St. Jude Medical, Cardiology Division, Inc.

Shape-memory polymer foam device for treating aneurysms

A system for treating an aneurysm in a blood vessel or vein, wherein the aneurysm has a dome, an interior, and a neck. The system includes a shape memory polymer foam in the interior of the aneurysm between the dome and the neck.
The Texas A&m University System

Biological information measurement apparatus and biological information measurement method

A biological information measurement apparatus includes an irradiation unit configured to irradiate a living body with light or sound waves as measurement waves; a detection unit configured to detect the measurement waves having passed through the inside of the living body; and a computational unit configured to obtain a change over time in blood flow rate and a change over time in blood vessel cross-sectional area based on a detection result from the detection unit, and to obtain a pulse wave propagation velocity from the change over time in blood flow rate or the change over time in blood vessel cross-sectional area.. .
Seiko Epson Corporation

Blood pressure sensors

An aspect of the disclosure pertains to a wrist-worn device that may be characterized by the following features: an external surface that is not in contact with the user when the wrist-worn device is worn; a force sensor; a ppg sensor disposed on the wrist-worn device; and control logic configured to: (i) generate one or more sensor data samples, each sensor data sample including data that links force data generated by the force sensor when a user presses a against the external surface at a given time with heart rate data obtained from the ppg sensor at the given time; and (ii) calculate an estimate of blood pressure from the one or more sensor data samples. As examples, the force sensor may be a force sensitive touch screen or film, a strain gauge integrating into the device, or a calibrated spring element configured to be pressed by the user..
Fitbit, Inc.

Pulse wave measurement device and blood pressure measurement device

A pulse wave measurement device includes an acceleration sensor that detects a vibration and a vibration transmitter that transmits a vibration caused by pulsation in a measured site, wherein a length of the vibration transmitter in a specific direction is longer than a length of the acceleration sensor in a longitudinal direction.. .
Nec Corporation

Processor device for endoscope, operation method thereof, and non-transitory computer readable medium

There is provided a processor device for an endoscope capable of accurately acquiring an observation distance. An endoscope system has an endoscope, and a light source device, and a processor device.
Fujifilm Corporation

Biological information measurement apparatus and biological information measurement method

A biological information measurement apparatus includes an irradiation unit configured to irradiate a living body with light or sound waves as measurement waves; a detection unit configured to detect measurement waves having passed through the inside of the living body; and a computational unit configured to obtain a change over time in blood flow rate and a change over time in blood vessel cross-sectional area based on a detection result from the detection unit, to divide a waveform, into a waveform for a progressive-wave component and a waveform for a reflected-wave component using the change over time in blood flow rate or the change over time in blood vessel cross-sectional area, and to obtain the degree of sclerosis of a blood vessel from the waveform for a progressive-wave component and the waveform for a reflected-wave component.. .
Seiko Epson Corporation

Blood pressure determination device, blood pressure determination method, recording medium for recording blood pressure determination program, and blood pressure measurement device

For the purpose of determining blood pressure with high precision, a blood pressure determination device of the present invention includes: pulse wave calculating means that calculates, on the basis of a pressure signal in a specific time period and of a pulse wave signal measured in the specific time period due to pressure related to the pressure signal, a plurality of timings at which the pulse wave signal satisfies a predetermined condition, a time period that represents a difference between the timings, and a pressure value of the pressure signal in the time period, and calculates pulse wave information that associates the time period with the pressure value; data extracting means that extracts a specific data range from the pulse wave information on the basis of an arterial viscoelasticity indicator; and blood pressure determining means that determines diastolic blood pressure on the basis of a correspondence relationship between a pressure value and a time period within the data range.. .
Nec Corporation

Nucleoside-containing compositions and methods for treating red blood cells

blood storage and/or rejuvenating compositions that include d-ribose and a nucleoside other than inosine (e.g., guanosine) are disclosed herein. Such compositions can be useful in methods for treating (e.g., storing and/or rejuvenating) red blood cells..
Viacell, Llc.

Portable devices and methods for measuring nutritional intake

A system for monitoring nutritional intake is described. The system includes a wearable housing configured for releasable attachment to a user; a biosensor supported by the wearable housing for disposition adjacent to a blood vessel; the biosensor configured to collect pulse profile data; an output device; and a processing circuit connected to the biosensor and the output device.
Blacktree Fitness Technologies Inc.

Marker for depression, assay method, determining depression, screening antidepressants, and kit

Disclosed herein are a method and a kit using a novel marker associated with depression. The marker for depression includes one or more selected from a noradrenaline transporter and a dopamine transporter.
Meijo University

Blood coagulation analyzer and blood coagulation analyzing method

A blood coagulation analyzer comprises: a light irradiation unit configured to apply light onto a container configured to store a measurement specimen containing a sample and a reagent, and comprising: light sources including a first light source configured to generate light of a first wavelength for blood coagulation time measurement, a second light source configured to generate light of a second wavelength for synthetic substrate measurement, and a third light source configured to generate light of a third wavelength for immunonephelometry measurement; and optical fiber parts facing the respective light sources; a light reception part configured to receive light transmitted through the container; and an analysis unit configured to analyze the sample using an electric signal outputted from the light reception part.. .
Sysmex Corporation

Method for improved accuracy of blood testing

This disclosed method improves the accuracy of testing blood for the levels of contaminant, such as lead, cadmium and mercury, in individuals. The method comprises cleaning the area where the skin will be penetrated to obtain the blood sample to remove the contaminant to be measured in the blood.
Esca Tech, Inc.

Equilibrium potential estimating method, equilibrium potential estimating device, concentration estimating device, program, medium and blood sugar estimating device

If it is determined to sweep the voltage, sweeping the voltage in an opposite direction to a sweep direction in the previous sweeping.. .

Improved process for the preparation of immunoglobulin g (igg)

The present invention is directed to processes for extracting igg from an unused waste precipitate produced during normal plasma fractionation processes via a separate fractionation process, thereby increasing the overall yield of igg from blood plasma.. .
Bio Products Laboratory Limited

Balloon catheter systems for delivery of dry drug delivery vesicles to a vessel in the body

Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles.
Caliber Therapeutics, Inc.

Catheter

A catheter that prevents excessive concentration of stress while providing sufficient flexibility to a distal end portion of the catheter, even when the catheter is inserted and curved in patient's a blood vessel. Thus, breakage of the catheter at a radiopaque marker is prevented/reduced.
Asahi Intecc Co., Ltd.

Hemodialysis device

A hemodialysis device is described herein. An exemplary hemodialysis device includes an import tube, a dialysis tube, and an export tube.

Method of decreasing blood sugar

The invention relates to a method of decreasing blood sugar by inhibition of α-glucosidase activity in a subject in need thereof, comprising administering pu-erh tea polysaccharides (ptps) to the subject, wherein the active ingredients in ptps are neutral sugar, protein, polyphenol, and uronic acids.. .
Chung Shan Medical University

Ophthalmic compositions

The present invention discloses novel ophthalmic preparations for the treatment of corneal pathologies comprising umbilical cord blood plasma.. .
Fondazione Irccs Ca' Granda-ospedale Maggiore Policlinico

Use of cord blood plasma to treat nk cell-mediated diseases and ifn-γ mediated diseases

The present invention shows that cb plasma contains soluble nkg2d ligands and that the incubation of pbmcs with cb plasma results in decreased cytotoxicity, decreased proliferation and inhibition of ifny production by nkg2d bearing cells, in particular, nk cells. Interaction of nkg2d with soluble nkg2d ligand leads to blocking of the nkg2d receptor, and renders nkg2d bearing cells refractory to activation and inhibits cell functions.
Instituto De Salud Carlos Iii

Piezoelectric compression stocking

The present disclosure provides a compression stocking that comprises a tubular fabric body and a piezoelectric material that is incorporated into the tubular fabric body. The piezoelectric material changes shape in response to actuation energy to generate a compressive force.
Dajustco Ip Holdings Inc.

Enhancement of aqueous flow

Drainage of body fluid from an area of undesirably high pressure can be accomplished by interconnecting an artificial non-blood fluid conduit with the vascular system. For example, an artificial non-blood fluid conduit can be inserted into the eye to fluidly interconnect the anterior chamber with a location of lower pressure.
Orange County Glaucoma, Pc

Method and allowing blood flow through an occluded vessel

A device arranged to sustain and/or provide at least partial patency of a small blood vessel exhibiting an occlusion, the device constituted of a tubular body expandable from a first small diameter state for manipulation to, and through, the occlusion of the small blood vessel and a second large diameter state, the inner dimensions of the second large diameter state being no more than 50% of the diameter of the small blood vessel at the occlusion location, the device presenting a conduit for blood flow through the occlusion when in the large diameter state. In one embodiment the small blood vessel is an intracranial blood vessel..
Perflow Medical Ltd.

Dissecting device and dissecting system

A dissecting device for dissecting tissue surrounding a blood vessel in a living body. The dissecting device includes a grasping section that includes an insertion lumen.
Terumo Kabushiki Kaisha

Treatment device

A treatment device is disclosed, which includes a dissecting section main body which is configured to dissect tissue in a living body when inserted into the living body along a blood vessel, and which has a slit permitting a branch vessel branched from the blood vessel to enter into the slit, a stanching section which is disposed at the slit and which presses and cauterizes the branch vessel introduced into the slit, and a cutting section which is disposed at the slit and which cuts the cauterized branch vessel.. .
Terumo Kabushiki Kaisha

Expandable body device and use

Disclosed herein are devices, designs, methods of manufacturing and using medical devices comprising expandable bodies for treating saccular vascular aneurysms and occluding segments of blood vessels and other biological conduits. Exemplary expandable bodies include hollow gold structures that can be folded, wrapped, and compressed, joined to a delivery device, advanced to location in the body of patient in need of treatment, expanded by injection of a fluid into the central void, and separated from the delivery device, remaining in place in an open, expanded form without the addition of support structures to the central void.
Metactive Medical, Inc.

Methods and devices for treatment of vascular defects

Methods of implanting a device in the lumen of a blood vessel are described. The method includes providing a microcatheter and a device.
Sequent Medical, Inc.

Dissecting device

A dissecting device that includes a grasping section and a dissecting member. The grasping section has an insertion lumen that permits an imaging device to be positioned therein.
Terumo Kabushiki Kaisha

System and adventitial tissue characterization

Disclosed herein is a system and method for characterizing adventitial tissue. In one aspect, a system and method is disclosed that characterizes tissue types within the adventitial tissue including nerve bundles and blood vessels.
Volcano Corporation

X-ray/intravascular imaging colocation method and system

In the present invention, a method and associated system is provided that produces a new sequence of combined x-ray/fluoro images obtained in synchrony with intravascular dataset/images. This synchronization is based on the time tags recorded at the acquisition of one dataset of the x-ray/fluoroscopic images and the intravascular images/datasets and the cardiac cycle correspondence between the combined x-ray/fluoro datasets/images.
General Electric Company

Intelligent inflatable cuff for arm-based blood pressure measurement

This disclosure provides devices and methods for estimating blood pressure using intelligent oscillometric blood pressure measurement techniques, where some implementations of the devices include multiple biometric sensors and/or can obtain sensor data from a connected device. In some implementations, the devices automatically determine an identity of a user.
Fitbit, Inc.

Method and the continous estimation of human blood pressure using video images

The invention described provides a way to use video image to estimate the human artery blood pressure reducing or completely eliminating the need for human contact (non invasive). Since video images can be stored and transmitted, the estimation of the blood pressure can be performed locally, remotely and in real time or offline..
Lakeland Ventures Development Llc

Systems and methods for modified pulse transit time measurement

A wearable apparatus selects at least two signal channels corresponding to an arterial signal, the channels associated with corresponding optical sensors of the wearable apparatus. Data is obtained from signal channels over a predetermined time.
Echo Labs, Inc.

Human metabolic condition management

Systems and methods for extracting blood glucose patterns and suggesting a behavior may include receiving, at a computing device comprising a processor, temporal data including information regarding glucose readings; identifying, by the computing device, at least one pattern based on metabolite levels extracted from the temporal data the model including variables corresponding to each of the patterns; formulating, by the computing device, a model for predicting a metabolic response; and storing the model on a data storage device. Based on the model, the behavior may be suggested to maintain a blood glucose level within a desired range..

E-triage: an electronic emergency triage system

An embodiment in accordance with the present invention provides a system that uses simple standardized patient information routinely collected at triage to distribute patients amongst triage levels based on critical and time-sensitive outcomes. The present invention estimates the probability of electronic medical record (emr) recorded events for patients at triage.
The Johns Hopkins University

Methionine aminopeptidase overexpression in the peripheral blood and peripheral blood mononuclear cells is a marker for colorectal cancer screening, diagnosis and prognosis

A method of screening/prognosis/diagnosis for colorectal cancer (crc) wherein methionine aminopeptidase 2 (metap2) levels are detected in a non-tumor sample such as peripheral blood, peripheral blood mononuclear cells (pbmc) or lymphocytes. Based on the metap2 levels, the individual may be selected for further testing..
Vastcon

System and in vitro blood vessel modeling

The present invention provides an in vitro blood vessel model for investigation of drug induced vascular injury and other vascular pathologies. The in vitro blood vessel model provides two channels separated by a porous membrane that is coated on one side by an endothelial cell layer and is coated on the other side by a smooth muscle cell layer, wherein said model is susceptible to the extravasation of red blood cells across said porous membrane due to drug induced vascular injury..
The Charles Stark Draper Laboratory, Inc.

Pericyte assay for transendothelial migration

A test animal for identifying blood vessel transendothelial migration-affecting factors or agents is described. The test animal comprises an implanted tissue mimicking model with a composite vascular structure comprising pericytes on test animal vasculature.
Case Western Reserve University

Vacuum-assisted plasma separation

A plasma separation system and process for providing filtered plasma from a blood sample is described. The system may include a blood separation well having a separation membrane for filtering the blood sample.
Siemens Healthcare Diagnostics Inc.

Device and detection of haemoglobin and its complexes

An electrochemically active device is provided for collecting and retaining a blood sample with at least a two-electrode member connected to conductive tracks. A receptor with an integral receptor-membrane arranged on the two-electrode member, to receive non-electrochemically active heamoglobin bioanalyte and its complexes from red blood cells (rbc) of said blood sample, through a lysing agent and convert the non-electrochemically active heamoglobin bioanalyte and its complexes, into an electrochemically active bioanalyte and its electrochemically active complexes.
Indian Institute Of Science

Contact-type patch, staining method using the same, and manufacturing method thereof

The present disclosure relates to a gel-phase patch that performs a function of assisting in staining during a staining process such as a process of coming into contact with a specimen such as blood to perform a staining function of staining the specimen, a process of fixing the specimen, or a process of forming an optimal ph at a specimen stained by a staining sample. According to an aspect of the present disclosure, a contact-type staining patch includes a staining solution that reacts with a specimen and a gel receptor provided as a gel matrix of a mesh structure in which a pore that accommodates the staining solution is formed and the mesh structure prevents the staining solution in the pore from leaking or degenerating, and having a contact surface that comes into contact with the specimen to transfer some of the staining solution to the specimen..
Noul Co., Ltd.

Contact-type patch, staining method using the same, and manufacturing method thereof

The present disclosure relates to a gel-phase patch that performs a function of assisting in staining during a staining process such as a process of coming into contact with a specimen such as blood to perform a staining function of staining the specimen, a process of fixing the specimen, or a process of forming an optimal ph at a specimen stained by a staining sample. According to an aspect of the present disclosure, a contact-type staining patch includes a staining solution that reacts with a specimen and a gel receptor provided as a gel matrix of a mesh structure in which a pore that accommodates the staining solution is formed and the mesh structure prevents the staining solution in the pore from leaking or degenerating, and having a contact surface that comes into contact with the specimen to transfer some of the staining solution to the specimen..
Noul Co., Ltd.

Pressure sensor, pressure sensor system, microphone, blood pressure sensor and touch panel

According to one embodiment, a pressure sensor includes a film portion, a sensor unit, and a structure body. The film portion has a front surface and is deformable.
Kabushiki Kaisha Toshiba

Blood glucose lowering compound

The present invention relates to the field of medicine and the treatment of diabetes or hyperglycemia within that field. More particularly, the invention relates to a compound that lowers blood glucose, pharmaceutical compositions containing such a compound, and therapeutic uses of such a compound..
Amunix Operating Inc.

Methods and systems for lowering blood pressure through reduction of ventricle filling

Methods and devices for reducing ventricle filling volume are disclosed. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure.
Backbeat Medical, Inc.

Drug treatment method and delivery device

Provided is a treatment method and a medical device that can intentionally and locally administer a drug to a lesion area appearing in a narrow blood vessel such as a retinal blood vessel and a spinal blood vessel. The treatment method has an introduction step of introducing a medical elongated body having a drug holder for holding a drug into a living body, an arrangement step of arranging the drug holder at a treatment target inside the living body, and a discharge step of discharging the drug to the treatment target by releasing the drug held by the drug holder..
Terumo Kabushiki Kaisha

Catheter grip

The present disclosure provides a catheter grip device that secures to a catheter shaft and provides easier manipulation of the catheter shaft for the user. For example, the catheter shaft, such as for an electrophysiology catheter, may insert into a patient's blood vessel.

System for analyzing vascular refill during short-pulse ultrafiltration in hemodialysis

A method includes: receiving measurements of a blood-related parameter corresponding to a patient undergoing hemodialysis; estimating a value of one or more hemodialysis treatment-related parameters by applying a vascular refill model based on the received measurements of the blood-related parameter, wherein the one or more hemodialysis treatment-related parameters are indicative of an effect of vascular refill on the patient caused by the hemodialysis; determining, based on the one or more estimated values of the one or more hemodialysis treatment-related parameters, a hemodialysis treatment-related operation; and facilitating performance of the treatment-related operation. The vascular refill model is a two-compartment model based on a first compartment corresponding to blood plasma in the patient's body, a second compartment based on interstitial fluid in the patient's body, and a semi-permeable membrane separating the first compartment and the second compartment..
Fresenius Medical Care Holdings, Inc.

Ventricular assist device method and apparatus

Apparatus for use with a ventricular assist device that is assisting cardiac function of a biological subject, the apparatus including an electronic processing device that determines a flow rate of blood through the ventricular assist device, analyses the flow rate to determine a flow parameter value at least partially indicative of a change in the flow rate during diastole; and uses the flow parameter value to either derive at least one blood pressure parameter value at least partially indicative of a blood pressure in the biological subject or control the ventricular assist device.. .
St Vincent's Hospital Sydney Limited

Device for prevention of shunt stenosis

A method and a kit for the prevention of venous stenosis associated with the use of hemodialysis av shunts. The kit may use a bifurcated needle for providing access to the shunt or blood vessel.
Technion Research & Development Foundation Ltd.

Lung volume reduction therapy using crosslinked non-natural polymers

One aspect of the invention relates to a hydrogel comprising a non-natural polymer comprising a plurality of pendant nucleophilic groups and a crosslinker comprising at least two pendant electrophilic groups. Another aspect of the invention relates to a hydrogel comprising a non-natural polymer comprising a plurality of pendant electrophilic groups and a crosslinker comprising at least two pendant nucleophilic groups.
Pulmonx

Soybean extracts and combinations thereof with polyethoxylated castor oil and other adjuvants for controling blood sugar levels and for hepatoprotection

Provided are compositions and methods using soy extracts and fractions thereof, optionally in combination with castor oil, for controlling blood sugar levels in a subject, treating liver damage and restoring liver function, treating, preventing, ameliorating, reducing or delaying the onset of acute or chronic toxic effect of a drug, treating an immune related disorder, and for enhancing the therapeutic effect of a therapeutic agent in a subject.. .
Natural Shield Israel 2016 Ltd

Methods of use of inhibitors of phosphodiesterases and modulators of nitric oxide, reactive oxygen species, and metalloproteinases in the treatment of peyronie's disease, arteriosclerosis and other fibrotic diseases

The present methods and compositions are of use for treatment of conditions involving fibrosis, such as peyronie's disease plaque, penile corporal fibrosis, penile veno-occlusive dysfunction, dupuytren's disease nodules, vaginal fibrosis, clitoral fibrosis, female sexual arousal disorder, abnormal wound healing, keloid formation, general fibrosis of the kidney, bladder, prostate, skin, liver, lung, heart, intestines or any other localized or generalized fibrotic condition, vascular fibrosis, arterial intima hyperplasia, atherosclerosis, arteriosclerosis, restenosis, cardiac hypertrophy, hypertension or any condition characterized by excessive fibroblast or smooth muscle cell proliferation or deposition of collagen and extracellular matrix in the blood vessels and/or heart. In certain embodiments, the compositions may comprise a pde-4 inhibitor, a pde-5 inhibitor, a compound that elevates cgmp and/or pkg, a stimulator of guanylyl cyclase and/or pkg, a combination of a compound that elevates cgmp, pkg or no with an antioxidant that decreases ros, or a compound that increases mmp activity..
Los Angeles Biomedical Research Institute At Harbor- Ucla Medical Center

Modular stent graft systems and methods with inflatable fill structures

An apparatus includes a first stent graft that is at least partially insertable into a first blood vessel. The first stent graft has a first end, a second end, an inside surface, and an outside surface.
Endologix, Inc.

Introducer sheath having a multi-layer hub

An introducer assembly includes an elongate sheath sized for insertion into a blood vessel of a patient and a hub. The hub can be coupled to a proximal portion of the sheath and can include a first hub portion and a second hub portion.
Abiomed, Inc.

Transthoracic pulmonary doppler ultrasound for evaluating the heart or lung via doppler shift power spectrum

Operation of a patient's heart or lungs may be analyzed by transmitting ultrasound energy into the patient's lung, and detecting doppler shifts of reflected ultrasound induced by moving borders between blood vessels in the lung and air filled alveoli that surround the blood vessels. Movement of the border is caused by pressure waves in the blood vessels that result in changes in diameter of those blood vessels.
Echosense Jersey Limited

Fluid collection device and related methods

Articles and methods for collecting and/or facilitating transfer of fluids are generally provided. In some embodiments, an article comprises a fluid collection region for introducing a fluid, such as a sample (e.g., blood sample) or a reagent, into a fluidic system.
Opko Diagnostics, Llc

Continuous analyte sensor

Disclosed herein are embodiments of a continuous analyte sensor that can be used to measure glucose or lactate levels in a patient, along with other analytes. In some embodiments, the sensor can be located in the tissue or a blood vessel of a patient, and a probe can be located on the skin of the patient generally adjacent to the sensor.
The Regents Of The University Of California

Catheter grip with hinge

The present disclosure provides a catheter grip device that secures to a catheter shaft and provides easier manipulation of the catheter shaft for the user. For example, the catheter shaft, such as for an electrophysiology catheter, may insert into a patient's blood vessel.

Device and measurement of intracranial pressure

The device for non-invasive monitoring of intracranial pressure (1) includes a measuring mat (2), processor unit (3), device for recording electrical activity of the heart (4), device for invasive measurement of arterial blood pressure (5), imaging device 6 and network connector (7). The measuring mat includes the processor unit (3) and sensors, at least one sensor (8) monitoring mechanical movement caused by the bloodstream dynamics.
Linet Spol. S.r.o.

Method for oscillatory non-invasive blood pressure (nibp) measurement and control unit for an nibp apparatus

There is provided a method for use in cuff-based oscillatory non-invasive blood pressure (nibp) measurement. The method comprises: progressively altering the volume of air in a cuff of a nibp measurement apparatus during a measurement period; obtaining a plurality of measurements of the flow rate of the air into/out of the cuff during the measurement period; obtaining a plurality of measurements of the air pressure in the cuff during the measurement period; and determining a relationship between quasi-static cuff compliance and cuff pressure by calculating the quasi-static cuff compliance at a plurality of instances during the measurement period, based on the flow rate measurements and the air pressure measurements obtained during the measurement period..
Koninklijke Philips N.v.

System and method to determine blood pressure

A system, method, and device for monitoring a physiological characteristic of a user includes a wearable monitoring device including one or more leds configured to emit light toward a user's skin tissue and two or more sensors laterally disposed along a longitudinal axis of an extremity of a user. Each sensor generates a signal based on an intensity of received light from a location against or adjacent to the sensor where a pulse wave resulting from a user's heart beat passes.
Garmin Switzerland Gmbh

Method and electronic device for cuff-less blood pressure (bp) measurement

A method and an electronic device for measuring blood pressure are provided. The method includes illuminating, by a ppg sensor included in the electronic device, skin of a user and measuring a ppg signal based on an illumination absorption by the skin.
Samsung Electronics Co., Ltd.

Blood pressure estimation based on pulse wave velocity

One aspect of the subject matter described in this disclosure can be implemented in a device capable of estimating blood pressure. The device includes two or more sensors capable of performing measurements along an artery.
Qualcomm Incorporated

Blood pressure measurement method, blood pressure measurement device, blood pressure measurement program, and recording medium for recording said program

A blood pressure measurement method of acquiring a change in a blood pressure with respect to time includes a pulse wave acquisition step of acquiring a time waveform based on a volume pulse wave, a dn point detection step of detecting a dn point, which corresponds to a dicrotic notch point in a blood pressure waveform indicating the change in the blood pressure with respect to time, in the time waveform, and a waveform correction step of correcting the time waveform so that a time waveform value at the dn point becomes a predetermined blood pressure value and acquiring the change in the blood pressure with respect to time.. .
Hamamatsu Photonics K.k.

Telemonitoring system !

Disclosed is a telemonitoring system and associated methods. A doctor creates a care plan for a patient with a chronic condition, such as diabetes.
Esvyda!, Inc.

Hgh determination for use to guide prevention of a major adverse cardiac event or a cardiovascular disease in a subject

A method of determining whether a subject has a vascular risk that can be reduced by blood pressure lowering therapy with antihypertensive drugs (e.g. Angiotensin converting enzyme inhibitor (ace inhibitor), angiotensin receptor blocker (arb), beta-adrenoreceptor blocker (beta-blocker) and/or statins) by determining the level of hgh, and/or its isoforms in a blood sample of said subject and comparing the determined level of hgh, and/or its isoforms in said blood sample with a pre-determined threshold..
Sphingotec Gmbh

Methods and segregation of particles

The disclosure relates to an apparatus for segregating particles on the basis of their ability to flow through a stepped passageway. At least some of the particles are accommodated in a passage bounded by a first step, but at least some of the particles arc unable to pass through a narrower passage bounded by a second step, resulting in segregation of the particles.
Angle North America, Inc.

Biological information measurement device, and biological informatoin measurement method using same

The present invention has an object of improving the measurement accuracy in a biological information measurement device, e.g., for measuring a blood glucose level. The device is configured to be able to change at least one of i) a voltage value to be applied to the second input terminal and the third input terminal (i.e., the blood component measurement counter electrode 7 and the blood component measurement working electrode 6) in the second biological information measurement mode d and ii) a voltage application time during which a voltage is applied to the second input terminal and the third input terminal in the second biological information measurement mode d based on the first biological information in the first biological information measurement mode a.
Panasonic Healthcare Holdings Co., Ltd.

Methods and compositions for analyzing glucose-6-phosphate dehydrogenase activity in blood samples

Methods and compositions for the detection of glucose-6-phosphate dehydrogenase (g6pd) enzyme activity in blood samples are described. Some embodiments disclosed herein provide methods for detecting g6pd activity in undiluted or minimally diluted blood samples, including obtaining a blood sample, and detecting g6pd activity present in the undiluted or minimally diluted blood sample by epifluorescence.
Becton, Dickinson And Company

Centrifuge and centrifuging a blood sample

A centrifuge comprising a rotor having a rotational axis, at least one receptacle for a blood sample container, controller means for controlling the rotational speed of the rotor, at least one optical transmitter for transmitting an optical signal, at least one optical receiver for registering the amplitude of the optical signal, where the optical signal is configured to pass through the blood sample container where the optical receiver detects the amplitude of the optical signal when it is directed through the blood sample container, where the amplitude of the optical signal reflects the translucency of the blood sample, where the controller means is configured to discontinue the rotational movement of the rotor when the amplitude of the optical signal over time has fulfilled a predefined pattern indicating that at least the fibrin compression phase of the blood sample is started.. .
Reapplix Aps

Apparatus and thermocyclic biochemical operations

An amplicon separation apparatus and process for enabling the identification of a plurality of target dna molecules in a sample such as blood, the apparatus including a consumable and a docking instrument for receiving the consumable. The consumable incorporates a reaction vessel heating station, a reaction vessel content transfer station, an amplicon size separation station, and a reader station.

Improved medicine delivery

Improved systems and methods for medicine delivery, and in particular, improved insulin pen needles and related devices are provided. Smart injection devices record and transfer data including medicine level, delivered dose, dose confirmation, and dose time and date.
Becton, Dickinson And Company

Adjusting insulin delivery rates

A method may include displaying to a user an interface at which the user inputs a fear of hypoglycemia index (fhi), the fhi corresponding to an acceptable probability of a blood glucose level being below a threshold blood glucose level. The method may also include receiving blood glucose data for a person with diabetes (pwd).
Bigfoot Biomedical, Inc.

Conjugate for treating malaria

A peptide-polymer conjugate is provided for use in treating malaria infections, and in particular terminal or drug resistant malaria infections. The conjugate is formed from a polymer to which a peptide having activity against a malaria parasite is co-valently attached.
Stellenbosch University

Opioid peptide

The invention also relates to pharmaceutical, nutritional and nutraceutical compositions comprising the peptide and to the use of the same for analgesic purposes, and/or for providing a feeling of satiety, and/or for lowering arterial blood pressure in a subject.. .

Vascular device marker attachment

A medical device can include an elongate manipulation member, and a thrombectomy device connected to the elongate manipulation member. The thrombectomy device can have a first configuration and a second configuration, the thrombectomy device being expandable from the first configuration to the second configuration.
Covidien Lp

Apparatus and treatment of in-stent restenosis

A catheter and catheter system can use energy tailored for remodeling and/or removal of target material proximate to a body lumen, often of stenotic material or tissue in the luminal wall of a blood vessel of a patient. An elongate flexible catheter body with a radially expendable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radically engage the luminal wall when the structure expands.
Boston Scientific Scimed, Inc.

Fluid jet tissue resection and cold coagulation (aquablation) methods and apparatus

An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses.
Procept Biorobotics Corporation

Systems, methods and devices for removing obstructions from a blood vessel

Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body.
Concentric Medical, Inc.

Vascular device visibility

A medical device can include an elongate manipulation member, and a thrombectomy device connected to the elongate manipulation member. The thrombectomy device can have a first configuration and a second configuration, the thrombectomy device being expandable from the first configuration to the second configuration.
Covidien Lp

Ultrasound devices for estimating blood pressure and other cardiovascular properties

An ultrasound cardiovascular measuring device may include an ultrasonic sensor system having an ultrasound transmitter layer configured to generate ultrasonic plane waves and a focusing layer that includes one or more lenses. One or more of the lenses may be configured to generate output signals corresponding to detected ultrasonic reflections.
Qualcomm Incorporated

Methods and devices for calculating blood pressure based on measurements of arterial blood flow and arterial lumen

An system for calculating blood pressure may include a sensor system and a control system. The control system may be capable of controlling one or more sensors of the sensor system to take at least two measurements, the at least two measurements including at least one measurement taken at each of two or more different measurement elevations of a subject's limb.
Qualcomm Incorporated

Medical apparatus

A medical apparatus includes a laser light source for blood vessel sensing configured to irradiate illumination light for detecting a blood vessel, a photodetector configured to detect return light of the illumination light, an optical-characteristic processing circuit configured to calculate, based on a detection result of the return light, at least one of information concerning scattering of blood cells in the blood vessel and information concerning absorption by blood, a blood-vessel-characteristic determination circuit configured to determine a characteristic of the blood vessel based on an optical characteristic calculation result, and a laser light source for guide configured to irradiate, based on the determined characteristic of the blood vessel, notification light on an irradiation near region including an irradiation region.. .
Olympus Corporation

Systems and methods for a blood collector with enhanced volume using capillary techniques

A blood sampler device includes a sampler body forming a hollow internal chamber with upper and lower openings, the sampler body including a sealing device disposed adjacent to the upper opening. The blood sampler device further includes a blood collector adapted to be inserted into the sampler body, the blood collector including a plurality of capillary channels..
Polymer Technology Systems, Inc.

Non-invasive measuring blood glucose in the human body utilizing a modified ceramic coaxial resonator

A system and method for measuring glucose levels in a user's blood without having to draw a blood sample. A wave energy source emits wave energy.

Blood pressure cuff assembly for ambulatory blood pressure monitor

A blood pressure cuff assembly for an ambulatory blood pressure monitor may include a hollow cuff and an elastic liner provided on the reverse side of the cuff. An airbag may be provided in the cuff.
Xi'an Shen Mindray Medical Electronics Research Institute Co., Ltd.

Time synchronization in a medical device system or network

Medical devices can perform a plurality of functions, such as sensing, monitoring, deriving and/or calculating various physiological statuses of a patient (e.g., blood pressure, temperature, respiration rate, etc.). Medical devices can also be used to image part or all of a patient's body, to deliver a treatment, or to manage information related to a patient's care.
Zoll Medical Corporation

Physiological sensor delivery device and method

An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve.
Acist Medical Systems, Inc.

Apparatus, chronic disease monitoring

An apparatus, system, and method for monitoring a person suffering from a chronic medical condition predicts and assesses physiological changes which could affect the care of that subject. Examples of such chronic diseases include (but are not limited to) heart failure, chronic obstructive pulmonary disease, asthma, and diabetes.
Resmed Sensor Technologies Limited

Sensor and device for lifetime imaging and detection applications

A method of luminance lifetime imaging includes receiving incident photons at an integrated photodetector from luminescent molecules. The incident photons being received through one or more optical components of a point-of-care device.
Tesseract Health, Inc.

Wireless blood pressure measuring techniques

According to certain inventive techniques, a blood pressure recording device includes at least one blood pressure sensor, a display configured to visually present received data, a wireless transceiver, a memory storing a reminder time, and a processor including a clock. The processor is configured to: receive blood pressure data from the at least one blood pressure sensor; process the blood pressure data to form a systolic reading and a diastolic reading; transmit the systolic reading and the diastolic reading to the display for visual presentation to a user; transmit the systolic reading and the diastolic reading to the wireless transceiver for wireless transmission; retrieve the reminder time from the memory; compare the reminder time to a time of the clock; and generate an alert when the clock time is equal to the reminder time..
Carematix, Inc.

Processor device for endoscope,operation method thereof, and non-transitory computer readable medium

There is provided a processor device for an endoscope capable of acquiring a blood vessel index value of a specific observation distance used for predetermined diagnostic criteria. A distance acquisition unit acquires a non-magnified observation distance at the start of the change of the imaging magnification, and acquires magnified observation distance at the end of the change of the imaging magnification.
Fujifilm Corporation





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