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Blood-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Method for non-invasive prenatal testing using parental mosaicism data
Natera, Inc.
June 22, 2017 - N°20170177786

Provided herein are methods for determining the ploidy state of one or more chromosome in a developing fetus. The subject methods provide for increase accuracy by utilizing information about the mosaicism level of one or more chromosomes of interest in the mother of fetus. The mosaicism level of one or more chromosomes of interest is determine for the maternal tissue ...
Systems and methods for assessing pulmonary gas transfer using hyperpolarized 129xe mri
Duke University
June 22, 2017 - N°20170176559

Methods and systems for assessing pulmonary gas exchange and/or alveolar-capillary barrier status include obtaining at least one mri image and/or image data of 129xe dissolved in the red blood cells (rbc) in the gas exchange regions of the lungs of a patient. The image is sufficiently sensitive to allow a clinician or image recognition program to assess at ...
Method
Mars, Incorporated
June 22, 2017 - N°20170176466

A method is provided, comprising feeding a cat a foodstuff comprising a protein to fat ratio of 1:0. 27 to 1:0. 63 on a gram:gram as fed or dry matter basis, and measuring the level of glucose-dependent insulinotropic polypeptide (gip) in a blood sample from the cat before and after feeding the foodstuff. A reduction in gip levels and/or maintaining low levels ...
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Markers and therapeutic indicators for glioblastoma multiforme (gbm)
Institute For Systems Biology
June 22, 2017 - N°20170176439

A signature of proteins occurring in glioblastoma multiforme (gbm) tissue comprised of 33 cell surface proteins (gbmsig) that distinguish subjects with gbm from healthy controls with more than 98% accuracy is described. In addition, four of the members of this signature are particularly useful as blood-borne markers of gbm. Certain other members of the signature are indicators of the possible efficacy of ...
Systems and methods for a versatile electrochemical test strip that may include one or more ...
Polymer Technology Systems, Inc.
June 22, 2017 - N°20170176410

A test strip for electrochemical testing of a blood analyte includes a plurality of test sites for the electrochemical testing of analytes on a single test strip. Each test site includes a first receiving port, the first receiving port for receiving a blood sample, the first receiving port at a first end of the test strip. The test site further ...
Biochemical analysis of pbmc
Todos Medical Ltd.
June 22, 2017 - N°20170176327

A method is provided comprising, obtaining an infrared (ir) spectrum of a peripheral blood mononuclear cells (pbmc) sample by analyzing the sample by infrared spectroscopy; and based on the infrared spectrum, generating an output indicative of the presence of a solid tumor or a pre-malignant condition. Other embodiments are also provided.
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Methods for assessing liver pathologies
The Chinese University Of Hong Kong
June 22, 2017 - N°20170175195

The present invention provides a new method for detecting or monitoring a liver disease in a subject that has no indication of any liver pathologies, by measuring the amount of concentration of albumin mrna in an acellular blood sample from the subject, and then comparing the amount or concentration of albumin mrna with a standard control.
Rapid, low-sample-volume cholesterol and triglyceride assays
Theranos, Inc.
June 22, 2017 - N°20170175168

Reagents, assays, methods, kits, devices, and systems for rapid measurement of cholesterol and cholesterol sub-fractions from a blood sample are provided. Total cholesterol, low density lipoprotein cholesterol, and high density lipoprotein cholesterol can be measured in a single assay using kinetic measurements, under conditions in which cholesterol sub-species are converted to a detectable product at distinct rates. The detectable product ...
Method for detecting a plasmodium infection
Siemens Healthcare Diagnostics Products Gmbh
June 22, 2017 - N°20170175162

The invention relates to a method for detecting a plasmodium infection in a patient blood sample, wherein a differential analysis of the polymorphonuclear neutrophil granulocytes in the sample is performed, and the distribution of the cell volume and the cell density, the number of thrombocytes in the sample, and the distribution of the cell density of the thrombocytes in the ...
Methods and apparatus for creating particle derivatives of hdl with reduced lipid content
Hdl Therapeutics
June 22, 2017 - N°20170174747

The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of hdl without substantially affecting ldl. These derivatives of hdl are particles with reduced lipid content, particularly reduced cholesterol content. These particles have the capacity to bind cholesterol and are administered to a patient to enhance cellular cholesterol efflux and reduce cholesterol ...
Tfpi inhibitors and methods of use
Baxalta Incorporated
June 22, 2017 - N°20170174727

The invention provides peptides that bind tissue factor pathway inhibitor (tfpi), including tfpi-inhibitory peptides, and compositions thereof. Peptide complexes also are provided. The peptides may be used to inhibit a tfpi, enhance thrombin formation in a clotting factor-deficient subject, increase blood clot formation in a subject, treat a blood coagulation disorder in a subject, purify tfpi, and identify a tfpi-binding ...
Medical systems, devices and methods
Baxalta Incorporated
June 22, 2017 - N°20170173262

There is disclosed a medical system comprising one or more sensors associated with one or more actuators. Various embodiments describe sensors and/or actuators, logic circuits, user interfaces, association schemes, communication schemes, security schemes, cryptographic schemes, medical management rules, social mechanisms, energy management schemes, time and/or space schemes, body analytes and/or biomarkers, blood glucose and/or interstitial glucose ...
Modular blood treatment systems, units, and methods
Fresenius Medical Care Holdings, Inc.
June 22, 2017 - N°20170173251

A portable adapter is provided that can include a closure system configured to control the flow of blood and/or dialysate between the adapter and a blood treatment apparatus. Modular systems are also provided that include the portable adapter engaged with various units such as a portable blood processing module, a non-portable base module, and/or a remote module. Methods ...
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Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using ...
Celonova Biosciences Germany Gmbh
June 22, 2017 - N°20170172933

Particles are provided for use in therapeutic and/or diagnostic procedures. The particles include poly[bis(trifluoroethoxy) phosphazene] and/or a derivatives thereof which may be present throughout the particles or within an outer coating of the particles. The particles can also include a core having a hydrogel formed from an acrylic-based polymer. Barium sulfate may also be provided to ...
Medical containers and system components with non-dehp plasticizers for storing red blood cell products, plasma ...
Fresenius Hemocare Netherlands B.v.
June 22, 2017 - N°20170172847

A container for blood or a blood component is provided, the container comprising one or more container walls defining an interior chamber, the container walls comprising one or more layers, the layers comprising or consisting of a composition comprising one or more polymeric materials and at least one extractable agent selected from the group consisting of a terephthalate ester, a ...
Intraluminal devices configured for directional expansion
Fresenius Hemocare Netherlands B.v.
June 22, 2017 - N°20170172777

Methods and devices useful, for example, in the field of angioplasty and stenting are disclosed. In some embodiments, the methods, devices and kits are configured for directional expansion inside a lumen, for example of a blood vessel obstructed by plaque. In some embodiments, the directional expansion displaces the plaque in a desired direction.
Electrochemical protection of conducting circuit in the body of a patient
Cook Medical Technologies Llc
June 22, 2017 - N°20170172644

The preferred embodiment provides apparatus for ablating a vessel by generating heat within a vessel to cause blood clotting to occlude the vessel. The apparatus includes an electrically resistive element at the distal end of the apparatus, the resistive element being uncoated and therefore in bare form. An alternating current supply feeds electrical current through the resistive element to cause ...
Direct stream hydrodynamic catheter system
Boston Scientific Limited
June 22, 2017 - N°20170172603

A direct stream hydrodynamic catheter system is provided for the removal of thrombus, lesions and the like including provisions for the infusion of drugs, lysing fluids and the like into a blood vessel. Physician controlled powered direct fluid jet streams emanate from a fluid jet emanatory in the form of robust radially directed fluid jet streams to impinge upon and ...
Aneursym occlusion system and method
Penumbra, Inc.
June 22, 2017 - N°20170172581

An aneurysm occlusion system includes a device positionable within a cerebral blood vessel covering a neck of an aneurysm on the blood vessel. The device includes an expandable tubular element having a lumen surrounded by a sidewall including a plurality of gaps. When expanded, the tubular element includes longitudinal standards arrayed helically in a proximal to distal direction. The standards ...
Neck-worn physiological monitor
Tosense, Inc.
June 22, 2017 - N°20170172517

The invention provides a neck-worn sensor that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate ...
Neck-worn physiological monitor
Tosense, Inc.
June 22, 2017 - N°20170172516

The invention provides a neck-worn sensor that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate ...
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