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Blood-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).

Molecular characterization of circulating tumor cells
Menarini Silicon Biosystems, Inc.
February 15, 2018 - N°20180045712

The disclosed invention includes methods and kits for the removal of white blood cells from samples of immunomagnetically enriched rare cells by treating the sample with a leukocyte marker conjugated to a hapten which adheres to the white blood cells and treating the resulting product with a second medium that adheres to the hapten of the white blood cells that ...
Method for evaluating coagulation ability of blood specimen, and reagent, reagent kit and device to ...
Sysmex Corporation
February 15, 2018 - N°20180045709

The present invention relates to a method for evaluating coagulability of a blood specimen obtained from a subject to whom a substance having a coagulation factor viii-substituting activity is administered. The present invention also relates to a reagent for blood coagulation analysis, a reagent kit for blood coagulation analysis, and an apparatus for blood coagulation analysis. Furthermore, the present invention ...
Methods for segregating particles using an apparatus with a size-discriminating separation element having an elongate ...
Angle North America, Inc.
February 15, 2018 - N°20180045708

The disclosure relates to an apparatus for segregating particles on the basis of their ability to flow through a stepped passageway. At least some of the particles are unable to pass through a narrower passageway bounded by a segregating step, resulting in segregation of the particles. The breadth of the leading edge of at least one step of the apparatus ...
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Method for production of heparin and heparan sulfate
Newsouth Innovations Pty Limited
February 15, 2018 - N°20180044442

This present disclosure relates to a method of producing a proteoglycan having anticoagulant activity, comprising of and providing a cell transfected with a recombinant nucleic acid encoding a core protein having one or more glycosaminoglycan attachment sites; and incubating the cell under conditions to promote the production of a proteoglycan comprising the core protein linked to heparin and/or hs ...
Substituted bridged urea analogs as sirtuin modulators
Glaxosmithkline Llc
February 15, 2018 - N°20180044338

Provided herein are novel substituted bridged urea and related analogs and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, ...
Assembly with a guide wire and a fixator for attaching to a blood vessel
Endovascular Development Ab
February 15, 2018 - N°20180043136

A fixator assembly comprising a fixator for fixing inside a blood vessel, the fixator being able to slide proximally along a guide wire. The assembly comprising means for preventing the fixator from moving distally of the preventing means. A tubular element for introduction into a blood vessel of a person, the tubular element comprising an end opening and a plurality ...
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Femoral arterial cannula capable of guiding bidirectional perfusion flow
Samsung Life Public Welfare Foundation
February 15, 2018 - N°20180043085

The present invention relates to a cannula for femoral arterial bidirectional (a heart direction and a distal lower extremity direction) perfusion. The cannula, which has a cannula tube to be inserted into a blood vessel of the femoral artery, includes a perfusion guide channel formed as a concave part from a predetermined portion of an inner circumferential surface at an ...
Magnetic filtration devices and methods related thereto
The Regents Of The University Of California
February 15, 2018 - N°20180043083

In vivo and ex vivo positionable magnetic filtration devices are provided that magnetically filter one or more therapeutic agents conjugated to a magnetic particle in blood flowing in a blood vessel.
Adaptive peritoneal dialysis intra-session adjustments for overall session optimization
Medtronic, Inc.
February 15, 2018 - N°20180043078

The invention relates to systems and methods for adjusting one or more dialysis parameters for delivering a peritoneal dialysis cycle to a patient based on patient or system parameters. The systems and methods include various sensors, flow paths, and processors to adjust the dialysis parameters used to deliver peritoneal dialysis therapy, for a specific peritoneal dialysis cycle. For example, a ...
Compounds for improving the half-life of von willebrand factor
Csl Behring Recombinant Facility Ag
February 15, 2018 - N°20180043012

The invention relates to a compound, preferably an antibody, capable of binding to the receptor protein clec10a for use in the treatment of a blood coagulation disorder.
Injectable microtissue systems, devices, and methods
The Trustees Of Columbia University In The City Of New York
February 15, 2018 - N°20180042970

Spheroid microtissues that can mimic native tissue-like structure and function, spheroid production methods that are high-throughput, suitable for efficient production, maintainable over long-term culture, and/or offer repeatable control over size distribution. Spheroids that have blood vessels, including spheroids with functional, blood-perfused vascular networks upon injection in vivo. Dissolvable hydrogel microwell arrays for high throughput parallel formation of spheroids in ...
Treatment of retinopathy of prematurity (rop)
The Cleveland Clinic Foundation
February 15, 2018 - N°20180042915

Disclosed herein are methods of treating retinopathy of prematurity (rop) in a premature and/or low birth weight infant in need thereof, comprising administering to the infant an effective amount of a compound represented by structural formula i, structural formula ia or structural formula ii described herein, or a pharmaceutically acceptable salt thereof. Also disclosed herein are methods of inhibiting ...
Perivascular drug delivery system
Wisconsin Alumni Research Foundation
February 15, 2018 - N°20180042844

The present technology provide compositions that are drug delivery systems for the sustained release of anti-stenotic drugs for the treatment and prevention of occlusion of blood vessels, particularly after perivascular surgery. The compositions include a hydrogel, unimolecular micelles dispersed within the hydrogel, and an effective amount of anti-stenotic drug dispersed within the unimolecular micelle. The hydrogel may be a di-or ...
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Methods and devices to remove thromboembolic material from blood vessels
February 15, 2018 - N°20180042628

A guard device for removal of thromboembolic material from a blood vessel includes a placement catheter having at least one axial lumen, a shield device having a pusher wire with an expandable braid assembly attached to its distal end and deliverable through the lumen of the placement catheter. The expandable braid assembly has a distal end with a distal tip ...
Blood clot aspiration catheter
February 15, 2018 - N°20180042623

A blood clot aspiration catheter includes an aspiration/flushing lumen having a distal portion that is insertable into a blood vessel of a patient, an aspiration device configured to create an aspiration phase to aspirate clot and blood into the aspiration/flushing lumen and a flushing phase to flush non-clotted blood from the aspiration/flushing lumen, a one-way valve configured ...
Surgical clamping devices
Vascular Devices Pty. Ltd.
February 15, 2018 - N°20180042613

Clamping devices for occluding a blood vessel comprise a pair of jaws for receiving the blood vessel therebetween, one or more inflatable membranes within the jaws and at least one handle coupled to the pair of jaws via a hollow arm. The at least one handle comprises an actuator coupled to the one or more inflatable membranes via the hollow ...
Medical-information processing apparatus and x-ray ct apparatus
Toshiba Medical Systems Corporation
February 15, 2018 - N°20180042569

A medical-information processing apparatus according to an embodiment includes processing circuitry. The processing circuitry acquires medical image data that is obtained during imaging on the subject in a resting state in the time phase where the relationship between the volume of blood flow and the pressure in a blood vessel in the cardiac cycle of the subject indicates a proportional ...
Sensors for prosthetic heart devices
St. Jude Medical, Cardiology Division, Inc.
February 15, 2018 - N°20180042555

Prosthetic heart devices may be implanted into the heart with a sensor coupled to the device, the sensor being configured to measure physiological data, such as blood pressure, in the heart. Devices that may employ such sensors include prosthetic heart valves and occlusion devices, although sensor systems may be deployed in the heart separate from other implantable devices. The sensors ...
Biological signal detecting device, biological signal processing device, and blood pressure measuring system
Ai Technology Inc.
February 15, 2018 - N°20180042499

A radio wave transmitted from an oscillation source through a first antenna is received each by a second antenna and a third antenna, and a synchronous detection is performed. Variation in impedance of a subject, i. E., variation in impedance of a human body, causes an effect equivalent to performing amplitude modulation with respect to an unmodulated radio wave, and ...
System and method for measuring vital signs
Pelletric Llc
February 15, 2018 - N°20180042496

A portable wearable computing device configured to continuously obtain data indicative of a patient's vital signs is disclosed. The portable wearable computing device includes a temperature sensor configured to obtain data indicative of body temperature of the patient. The portable wearable computing device further includes a blood oxygen saturation sensor configured to obtain data indicative of amount of oxygen present ...
Body-worn pulse oximeter
Sotera Wireless, Inc.
February 15, 2018 - N°20180042495

The invention provides a body-worn system that continuously measures pulse oximetry and blood pressure, along with motion, posture, and activity level, from an ambulatory patient. The system features an oximetry probe that comfortably clips to the base of the patient's thumb, thereby freeing up their fingers for conventional activities in a hospital, such as reading and eating. The probe secures ...