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Bioactive patents



      
           
This page is updated frequently with new Bioactive-related patents. Subscribe to the Bioactive RSS feed to automatically get the update: related Bioactive RSS feeds.

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Date/App# patent app List of recent Bioactive-related patents
04/10/14
20140099389
 Topical anti-inflammatory combination patent thumbnailnew patent Topical anti-inflammatory combination
Provided, among other things, is a method of treating or ameliorating an indication of non-mucosal topical tissue comprising periodically applying to such disease affected tissue a composition comprising: an effective amount of an appropriate composition of herbal bioactive comprising active(s) of one or more of sambucus nigra, centella asiatica or echinacea purpurea, and an effective amount of a quaternary ammonium surfactant.. .
04/10/14
20140099370
 Controlled release of biologically active compounds patent thumbnailnew patent Controlled release of biologically active compounds
The present invention relates to biodegradable polymers (e.g., polyesters and polyester amides) derived from functionalized biologically active compounds that can provide site specific delivery of bioactive compounds upon biodegradation in a controlled manner.. .
04/03/14
20140094414
 Composition for preventing or treating neurodegenerative disease including bioactive peptide as effective component patent thumbnailComposition for preventing or treating neurodegenerative disease including bioactive peptide as effective component
There is provided a new use of protein hydrolysates and peptide derived from seahorses for preventing or treating a neurodegenerative disease, and more particularly a composition and health functional foods for preventing or treating a neurodegenerative disease including seahorse protein hydrolysates or peptide isolated and purified from the same as an effective component.. .
04/03/14
20140093912
 Methods of making bioactive collagen medical scaffolds such as for wound care dressings, hernia repair prosthetics, and surgical incision closure members patent thumbnailMethods of making bioactive collagen medical scaffolds such as for wound care dressings, hernia repair prosthetics, and surgical incision closure members
A method of preparing a crosslinked, collagen-based medical scaffold is provided, comprising: (a) immersing a sample of fibrous and/or non-fibrous collagen in a buffered acidic, aqueous solution comprising an alcohol; (b) contacting the collagen in solution with a catalytic component comprising 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride for a time at least sufficient to effect reaction between amino and carboxyl groups present on the collagen and to yield crosslinked collagen that is resistant to pronase degradation; and (c) drying the crosslinked collagen to yield a porous, crosslinked collagen article wherein the porous, crosslinked collagen article demonstrates a pore size of 10-500 microns. Also provided are bioactive collagen medical scaffolds for wound care dressings, hernia repair prosthetics, and surgical incision closure members, prepared using the method above..
03/27/14
20140087000
 Method and system for treatment of biological tissue patent thumbnailMethod and system for treatment of biological tissue
A composition for reconstruction, replacement or repair of damaged or diseased biological tissue comprising an extracellular matrix (ecm) composition that includes an ecm scaffold component derived from a mammalian source and at least one additional bioactive component selected from the group consisting of a statin and a chitin derivative.. .
03/20/14
20140081192
 Primary dressing for moist wound healing, and method for producing said primary dressing patent thumbnailPrimary dressing for moist wound healing, and method for producing said primary dressing
The invention relates to a primary dressing for moist wound healing with a reduced risk of inflammation. The elastic primary dressing according to the invention for moist wound healing is in the form of a lattice or a netting made of elongated elastic bodies, said lattice or netting containing non-resorbable elongated bodies that consist of silicone and optionally at least one additive selected from active pharmacological ingredients, collagens, hydrocolloids, and/or dyes.
03/20/14
20140080096
 Guided tissue regeneration membrane patent thumbnailGuided tissue regeneration membrane
A guided tissue regeneration membrane has a top surface, a bottom surface and the two surfaces are characterized by the plurality of through conical holes. Each of the plurality of through holes has a base opening on the top surface and a tip opening on the bottom surface.
03/20/14
20140079834
 Bioactive fractions and compounds from dalbergia sissoo for the prevention or treatment of osteo-health related disorders patent thumbnailBioactive fractions and compounds from dalbergia sissoo for the prevention or treatment of osteo-health related disorders
The present invention relates to bioactive fractions and compounds from dalbergia sissoo for the prevention or treatment of osteo-health related disorders. The present invention relates in the field of pharmaceutical composition that provides new plant extracts, their fractions and pure compound isolated from natural sources that are useful for the prevention and/or treatment of various medical indications associated with estrogen dependent or independent diseases or syndromes or disorders preferably in the prevention or treatment of estrogen dependent or independent diseases or syndromes or disorders caused in humans and animals, and achievement of peak bone mass during skeletal growth and health in humans and animals.
03/20/14
20140079789
 Bioglass with glycosaminoglycans patent thumbnailBioglass with glycosaminoglycans
One or more particles of bioactive glass coated with a glycosaminoglycan, wherein the glycosaminoglycan is bound to the bioactive glass and methods of treatment using such particles.. .
03/20/14
20140079757
 Oral drug delivery formulations patent thumbnailOral drug delivery formulations
The invention generally relates to the preparation and use of consumable products for delivering a bioactive agent to an oral cavity of a mammal. In certain embodiments, the invention provides a consumable product that releases a bioactive agent within an oral cavity of a mammal, the product including a polymer matrix and one or more bioactive agents, in which the matrix is of a heterogeneous thickness..
03/20/14
20140079743
Coatings of acrylamide-based copolymers
An implantable device including a conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided.. .
03/20/14
20140076763
Peelable pouch for transdermal patch and method for packaging
A peelable pouch comprises a substantially flat enclosure formed by first and second opposing flexible plies. A seat extends along at least a portion of a perimeter of the opposing plies.
03/20/14
20140075993
Fabrication of porous glass bioscaffolds by sol-gel and polymer sponge methods
Provided herein are biocompatible scaffolds and methods of preparing such bioscaffolds. The methods provide a superior high surface area, interconnected nanomacroporous bioactive glass scaffold, by combining a sol-gel process and polymer sponge replication methods.
03/13/14
20140072640
Coating method
A method of coating an article includes the steps of providing a powder comprising coated particles; and spray coating the powder onto a surface of the article to form a composite coating. The spray coating may be carried out by combustion spraying, gas plasma spraying, including vacuum plasma spraying (vps), and cold spraying.
03/13/14
20140072544
Polybacterial preparation with health benefits: antioxidant effect, reduction of cholesterol concentration, anti-inflammatory immunomodulating effect and release of bioactive peptides inhibiting angiotensin-converting enzyme
This invention relates to polybacterial probiotic preparation, which includes new strains of lactic acid bacteria lactobacillus gasseri 7/12 nbimcc no. 8720, lactobacillus plantarum f12 nbimcc no 8722 and lactobacillus helveticus a1, nbimcc no 8721 and has the following set of properties: antioxidant, hypocholesterolemic effect, anti-inflammatory immunomodulating effect, ability to release bioactive peptides that inhibit angiotensin-converting enzyme (ace), which is responsible for the high blood pressure.
03/06/14
20140066694
Immobilized bioactive hydrogel matrices as surface coatings
The present invention is directed to a stabilized bioactive hydrogel matrix coating for substrates, such as medical devices. The invention provides a coated substrate comprising a substrate having a surface, and a bioactive hydrogel matrix layer overlying the surface of the medical device, the hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component, the first and second high molecular weight components each being selected from the group consisting of polyglycans and polypeptides, wherein at least one of the first and second high molecular weight components is immobilized (e.g., by covalent cross-linking) to the surface of the substrate..
03/06/14
20140065216
Bioactive dose having containing a material for modulating ph of a bodily fluid to help or hinder
A bioactive dose for delivering a bioactive agent to a mammal, includes a solid bioactive dosage unit containing at least one bioactive agent and a rapid release coating provided on at least one outer surface of the solid bioactive dosage unit, the rapid release coating containing a material having a property of rapidly modulating a ph of bodily fluids in which the material comes in contact in a direction towards an ideal absorptive ph or towards an ideal ph to hinder absorption of the at least one bioactive agent given the pka that least at one bioactive agent. A modified liquid that is administered prior to, contemporaneous with, or following the delivery of a bioactive agent is also described.
02/27/14
20140058188
Energetic modulation of nerves
In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another.
02/27/14
20140056963
Extended production of nitric oxide from a microencapsulated nitrite salt and an aqueous acidified gel
Methods and compositions are provided for generating and applying long-lasting therapeutic nitric oxide (no) gas from the reaction of a least one microencapsulated nitrite salt and an activating volume of an aqueous acidified gel that has sufficient acidity to convert the nitrite salt to a nitric oxide (no) and further provides a reducing property that retains the no in bioactive form. .
02/20/14
20140053299
Pufa polyketide synthase systems and uses thereof
Disclosed are the complete polyunsaturated fatty acid (pufa) polyketide synthase (pks) systems from schizochytrium, and biologically active fragments and homologues thereof. More particularly, this invention relates to nucleic acids encoding such pufa pks systems, to proteins and domains thereof that comprise such pufa pks systems, to genetically modified organisms (plants and microorganisms) comprising such pufa pks systems, and to methods of making and using the pufa pks systems disclosed herein.
02/20/14
20140051643
Anticancer agent
The present invention thus provides microbial products as anticancer agents and pharmaceutical compositions comprising isolated and purified proteins or synthetic peptides, and methods of using them for the treatment of cancer. It is very important to develop new anticancer bioactive peptides having high activity and low toxicity; given that most currently available anticancer therapies either have significant toxicity, and/or are prone to development of resistance..
02/20/14
20140051571
Bacillus megaterium bioactive compositions and metabolites
Provided are bioactive compositions and metabolites derived from bacillus and particularly bacillus megaterium cultures responsible for controlling pests as well as their methods of use for controlling pests. Further provided are pesticidal bacillus megaterium strains..
02/20/14
20140050765
Devices and methods for tissue engineering
A resorbable tissue scaffold in a glass ceramic composition forms a rigid three-dimensional porous matrix having a bioactive composition. Porosity in the form of interconnected pore space is provided by the space between the glass-ceramic fiber forming the porous matrix.
02/20/14
20140050689
Tissue grafted with a biodegradable polymer
Novel implantable tissue fixation methods and compositions are disclosed. Methods and compositions of tissue, fixed using polymeric and/or variable length crosslinks, and di- or polymercapto compounds are described.
02/13/14
20140046401
Retinal prosthesis
A retinal prosthesis including a microelectrode array, a polymer layer and a layer of bioactive molecule is provided. The microelectrode includes a plurality of microelectrodes.
02/13/14
20140046019
Hydroswellable, segmented, aliphatic polyurethanes and polyurethane ureas
Hydroswellable, absorbable and non-absorbable, aliphatic, segmented polyurethanes and polyurethane-urea capable of swelling in the biological environment with associated increase in volume of at least 3 percent have more than one type of segments, including those derived from polyethylene glycol and the molecular chains are structurally tailored to allow the use of corresponding formulations and medical devices as carriers for bioactive agents, rheological modifiers of cyanoacrylate-based tissue adhesives, as protective devices for repairing defective or diseased components of articulating joints and their cartilage, and scaffolds for cartilage tissue engineering.. .
02/13/14
20140046018
Biodegradable polymer - bioactive moiety conjugates
The invention relates to a biodegradable polymer comprising a plurality of releasable bioactive moieties, the releasable bioactive moieties being pendant from and covalently bonded to the biodegradable polymer backbone, wherein the biodegradable polymer backbone is formed from monomeric units that are each coupled via a biodegradable moiety, and wherein the bioactive moieties are capable of being released at a rate equal to or faster than the rate of biodegradation of the polymer backbone.. .
02/13/14
20140044769
Composite absorbable/biodegradable rings for controlled drug delivery
A fiber-reinforced composite ring for the controlled release of at least one bioactive agent includes a biocompatible matrix reinforced with absorbable/biodegradable fibers capable of providing the mechanical properties needed for inserting and maintaining the ring in a body cavity for a desired period of time. Such ring system as can be used for the intravaginal, intraperitoneal, and subcutaneous delivery of at least one bioactive agent, including those used as contraceptives, antimicrobial agents, and/or antiviral agents, as well as those for the treatment of cancer..
02/13/14
20140043588
Contact lens use in the treatment of an ophthalmologic condition
The disclosure relates to the use of contact lenses for treating ophthalmologic conditions, such as presbyopia, induced myopia, computer vision syndrome, insufficient accommodation, or a condition associated with insufficient accommodation. The contact lens may be selected based on a measured sagittal depth and/or eccentricity of the cornea.
02/06/14
20140039479
Energetic modulation of nerves
In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another.
02/06/14
20140039163
Cholesterol-dependent cytolysin variant and use thereof in dds
The present invention provides a carrier capable of delivering a medical agent capsule encapsulating a medical agent to various target cells and tissues to cause the medical agent to be taken therein in an efficient and highly safe manner, and a drug delivery system using the carrier. The carrier has a cell or tissue specific antibody bound to an antibody binding domain of a cholesterol-dependent cytolysin variant of the present invention.
02/06/14
20140039052
Formulations of lipophilic bioactive molecules
This invention provides aqueous and non-aqueous clear formulations including at least one lipophilic bioactive molecules and an amphiphilic solubilizing agent. Exemplary aqueous formulations include a water-soluble reducing agent, which diminishes or prevents chemical degradation of the lipophilic bioactive molecule.
02/06/14
20140037743
Microencapsulated bioactive agents for oral delivery and methods of use thereof
The presently claimed and disclosed inventive concept(s) contemplates a novel polymeric oral dosage form (transmucosal delivery vehicle) for delivery of pharmaceutical and nutriceutical bioactive agents to the mucosa and bloodstream of the intestine. The oral dosage form of the presently claimed and disclosed inventive concept(s) comprises a polymeric coating which encapsulates the bioactive agent and inhibits degradation and dissolution of the bioactive agent within the stomach and within the lumen of the intestine until after passing through the mucosal wall of the small and/or large intestine.
02/06/14
20140037708
Composition for spatio and/or temporal release of bioactive material
The present invention provides a biocompatible composition that comprises a bioactive material and a method for using the same. In particular, the composition of the invention is useful for spatio and/or temporal release of the bioactive material.
02/06/14
20140035201
Components incorporating bioactive material
There are provided methods of producing a component incorporating a bioactive material. In one embodiment the method comprises: (a) using a screw extruder to mix a polymeric material (i) with a bioactive material (ii) and melt the polymeric material (i); and (b) making a component by moulding; and wherein the polymeric material (i) is of a type which includes: (i) phenyl moieties; (ii) ketone moieties; and (iii) ether moieties.
01/30/14
20140031950
Bone graft materials and methods
Compositions, materials, methods and kits for bone grafting are described. In some embodiments, a bone graft composition includes about 15% to about 20% by weight collagen, about 55% to about 70% by weight bioactive glass, and about 15% to about 30% by weight a calcium phosphate.
01/30/14
20140031303
Bioactive hybrid of ionic/polyhydroxyl, lipophilic and covalently reactive moieties and method of use
A combination of the following three structures in a single molecule imparts a surprisingly broad range of beneficial effects in promoting and maintaining health. First, a strongly hydrophilic moiety, either a cation or anion or a polyhydroxyl group, with two or preferably three or more hydroxyl groups.
01/30/14
20140031289
Poly(organophosphazene) containing degradation controllable ionic group, preparation method thereof and use thereof
The present invention relates to a thermosensitive phosphazene-based polymer having a degradation controllable ionic group, a use thereof, and a use thereof as a material for delivering bioactive substances. The phosphazene-based polymer according to the present invention has the thermosensitivity of showing the temperature-dependent sol-gel phase transition.
01/30/14
20140031285
Photodegradable groups for tunable polymeric materials
Here, we present a photodegradable microparticle system that can be employed to entrap and deliver bioactive proteins to cells during culture. By using a photosensitive delivery system, experimenters can achieve a wide variety of spatiotemporally regulated release profiles with a single microparticle formulation, thereby enabling one to probe many questions as to how protein presentation can be manipulated to regulate cell function.
01/30/14
20140030309
Disrupted cartilage products
This invention provides disrupted cartilage products, methods of manufacturing disrupted cartilage products, and methods of treating a subject comprising administering a cartilage product. The cartilage products are manufactured by a method comprising disrupting a collagen matrix, e.g.
01/23/14
20140025035
Multi-lumen biologic-delivering device
Arrangements and methods for delivering bioactive agents and/or cells into an extended volume of tissue are disclosed. In one embodiment, a cell-delivering needle arrangement has a tube positioned within a tube and fixedly attached to a wall thereof.
01/23/14
20140024992
Cylindrical structure having lumen to be implanted into human body
A cylindrical structure having a lumen to be implanted into a human body. The cylindrical structure has a coating layer formed on at least one part of an inner surface of either or both ends of the cylindrical structure, wherein the coating layer includes a polymer for drug release control and a bioactive material..
01/23/14
20140024714
Artificial oil bodies
The present invention relates to artificial oil bodies comprising oleosin (which, as presently defined, also encompasses caleosin, steroleosin and polyoleosin), a surfactant such as a phospholipid, and an oil comprising fatty acids, such as polyunsaturated fatty acids having four or more double bonds. The present invention also relates to methods of preparing said artificial oil bodies.
01/23/14
20140023711
Bioactive surface capable of genetically modifying biological cells or tissues and use thereof
The invention relates to a bioactive surface comprising a polymer matrix, a connecting complex comprising at least one compound covalently bound to the surface of the polymer matrix, and a gene transfer vector bound to the connecting complex, wherein the compound of the complex is covalently bound to the transfer vector using a group selected from among carboxyl, amino, isocyanate and hydroxyl. The invention also relates to the use of the bioactive surface for transferring a nucleic acid to a cell.
01/16/14
20140018339
Methods for treating chronic or unresolvable pain and/or increasing the pain threshold in a subject and pharmaceutical compositions for use therein
Methods are provided for reducing chronic inflammatory pain, increasing the levels of endogenous opioid peptides, as well as increasing the pain threshold of a subject having symptoms of androgen deficiency, comprising transdermally administering a composition comprising a bioactive androgen on a daily basis. In addition, the invention also relates to increasing the levels of endogenous opioid peptides in a human subject by administering an androgen composition to the subject.
01/16/14
20140017292
Methods of manufacturing cartilage products
This invention provides porated cartilage products and methods of producing porated cartilage products. Optionally, the cartilage products are sized, porated, and digested to provide a flexible cartilage product.
01/16/14
20140017283
Porated cartilage products
This invention provides porated cartilage products, methods of producing porated cartilage products, and methods of treating subjects by administering cartilage products. Optionally, the cartilage products are sized, porated, and digested to provide a flexible cartilage product.
01/16/14
20140017281
Novel ionically crosslinked materials and methods for production
Compositions including crosslinked collagen and bioactive glass having an average pore size of at least 100 microns and methods of preparation thereof.. .
01/09/14
20140012222
Long term drug delivery devices with polyurethane-based polymers and their manufacture
This invention is related to the use of polyurethane-based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs..
01/09/14
20140011742
Bioactive peptides and proteins containing bioactive peptides, their uses and processes for making the same
A process for treating a protein before hydrolytic digestion, the process comprising exposing the protein to at least one cycle of microwave irradiation to produce a microwave treated protein containing one or more bioactive peptides. Further hydrolyzing the microwave treated protein to release at least one of the one or more bioactive peptides.
01/09/14
20140011739
Protozoan variant-specific surface proteins (vsp) as carriers for oral drug delivery
The invention provides compositions for oral delivery and methods of treatment using vsp carriers, such as giardia sp. Variable surface proteins (vsp), to deliver therapeutic agents.
01/09/14
20140011224
Novel bacterial strain of achromobacter sp. mtcc 5605 and a highly enantioselective epoxide hydrolase isolated therefrom
The present invention relates to a novel epoxide hydrolase enzyme which aims to achieve a high degree of resolution towards a broader range of substrates with high enantioselectivity and yields with minimal product inhibition. The invention further relates to a new bacterial strain achromobacter sp.
01/09/14
20140010885
Self-assembling nanoparticle drug delivery system
A self-assembling nanoparticle drug delivery system for the delivery of various bioactive agents including peptides, proteins, nucleic acids or synthetic chemical drugs is provided. The self-assembling nanoparticle drug delivery system described herein includes viral capsid proteins, such as hepatitis b virus core protein, encapsulating the bioactive agent, a lipid layer or lipid/cholesterol layer coat and targeting or facilitating molecules anchored in the lipid layer.
01/09/14
20140010858
Polymers for implantable devices exhibiting shape-memory effects
The present invention is directed to polymeric compositions comprising a biodegradable copolymer that possesses shape-memory properties and implantable devices (e.g., drug-delivery stents) formed of materials (e.g., a coating) containing such compositions. The polymeric compositions can also contain at least one non-fouling moiety, at least additional biocompatible polymer, at least one biobeneficial material, at least one bioactive agent, or a combination thereof.
01/09/14
20140010770
High unsaponifiables and methods of using the same
Materials with high levels of unsaponifiable matter, such as extracts from plants, produce hydrolysates with unique properties. The application of a hydrolysis process to materials, particularly materials with a high level of unsaponifiables (e.g., at least 6 weight percent of the material), produces a product with properties significantly different from those products resulting from the conventional saponification of materials with less than 6 weight percent of unsaponifiables.
01/02/14
20140005674
Multi-lumen central access vena cava filter apparatus for clot management and method of using same
A combined multi-lumen central access catheter and an embolic filter including ports proximal and distal the filter for fluid infusion and/or pressure sensing and infusion ports in the catheter to permit infusion of bioactive agents, flushing agents and/or contrast agents and managing the capture of the clot thereafter.. .
01/02/14
20140005541
Coated medical device
A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon.
01/02/14
20140005097
Bioactive peptides and methods of using same
Disclosed are peptide ligands for g-protein coupled receptors that are useful for treating disorders associated with g-protein coupled receptor activation.. .
01/02/14
20140004200
Polymer compositions with bioactive agent, medical articles, and methods
A polymer composition that includes a hydrophilic amine-containing polymer, an optional secondary organic polymer, an optional foaming agent, and a bioactive agent distributed therein, wherein the bioactive agent is selected from the group consisting of a silver compound, a copper compound, a zinc compound, and combinations thereof.. .
01/02/14
20140004199
Drug carrier for tumor-targeted therapy, its preparation method and its use
The present invention discloses a drug carrier with the capability of systemic administration through intravenous injection, its preparation methods and it is used for tumor gene therapy, it is belong to the field of tumor-targeted therapy. The carrier of the present invention is a novel liposome which is composed of dotap or its analogue and lecithin or its derivative in molar ratio of 20:(7-13), it can form stable complex with bioactive materials, and can deliver these bioactive material to the targeted cells cultured in vitro or in vivo.
01/02/14
20140004040
Methods and compositions for targeting sites of neovascular growth
Compositions and methods for targeted delivery to and detection of sites of neovascular growth, including tumor vasculature, are provided. Compositions include polypeptides conjugated to or complexed with a bioactive compound, wherein the polypeptide is capable of binding to an oec or a circulating progenitor thereof.
12/26/13
20130345740
Multi-lumen central access vena cava filter apparatus for clot management and method of using same
A combined multi-lumen central access catheter and an embolic filter including ports proximal and distal the filter for fluid infusion and/or pressure sensing and infusion ports in the catheter to permit infusion of bioactive agents, flushing agents and/or contrast agents and managing the capture of the clot thereafter.. .
12/26/13
20130345627
Multi-lumen central access vena cava filter apparatus for clot management and method of using same
A combined multi-lumen central access catheter and an embolic filter including ports proximal and distal the filter for fluid infusion and/or pressure sensing and infusion ports in the catheter to permit infusion of bioactive agents, flushing agents and/or contrast agents and managing the capture of the clot thereafter.. .
12/26/13
20130345314
Compositions and methods for treating a damaged cardiovascular element
In the present invention, the applicants describe methods and compositions of treating damaged cardiovascular elements and cardiovascular conditions including hypotension, atherosclerotic lesions, vulnerable plaque, and acute myocardial infarct. The applicants demonstrate the ability of a biomembrane sealing agent to accumulate on the walls of damaged blood vessels and help improving mean arterial pressure following tissue injury.
12/26/13
20130344520
Thrombin substrate and assay for determining the level of bioactive thrombin in a sample
Substrates for thrombin and assays for determining the level of bioactive thrombin in a sample are disclosed, wherein the substrate has the general formula: a-x—z-a′ wherein one of either a or a′ comprises a luminescent chelate and the other one of a or a′ comprises a first partner of a binding pair, x forms a tri- or tetra-peptide, and z comprises a linker.. .
12/26/13
20130344174
Bioactive fractions and compounds from polygonum genus, their use in anti-diarrhea and the method of preparation
The present invention discloses the utility of factions and compounds from polygonum chinense linn in anti-diarrhea. The invention also includes their preparation and application method for anti-diarrhea treatment..
12/26/13
20130344126
Bioerodable poly(etheresteramides) and medical article uses
Bioerodable poly(etheresteramides) and matrices formed therefrom, such as medical device coatings, are described. The matrices show desirable erosion properties desirable for therapeutic use.


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Bioactive topics: Polypeptide, Aqueous Solution, Distributed, Therapeutics, Steoporosis, Intravenous, Osteoporosis, Side Effects, Computer Program, Biopolymer, Sacroiliac Joint, Immobilization, Condensation, Antimicrobial Resistance, Aluminum Phosphate

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