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Baclofen patents



      
           
This page is updated frequently with new Baclofen-related patent applications. Subscribe to the Baclofen RSS feed to automatically get the update: related Baclofen RSS feeds. RSS updates for this page: Baclofen RSS RSS



Date/App# patent app List of recent Baclofen-related patents
08/27/15
20150238452 
 Baclofen and acamprosate based therapy of macular degeneration disorders patent thumbnailBaclofen and acamprosate based therapy of macular degeneration disorders
The present invention relates to combinations and methods for the treatment of macular degeneration disorders. More specifically, the present invention relates to novel combinatorial therapies of age related macular degeneration based on baclofen and acamprosate combination..
Pharnext


08/13/15
20150224092 
 Nootropic compositions for improving memory performance patent thumbnailNootropic compositions for improving memory performance
The invention relates to compositions and methods for improving memory and related functions as alertness, attention, concentration, learning, and language processing. More particularly, the invention relates to compositions comprising at least two drugs selected from cinacalcet, baclofen, acamprosate, mexiletine, sulfisoxazole and torasemide useful to enhance memory and related functions in healthy subjects or subjects suffering from conditions or disorders having a negative impact on their memory..
Pharnext


05/28/15
20150148420 
 Methods for treating insomnia patent thumbnailMethods for treating insomnia
Methods for treating insomnia are disclosed. The methods are directed to administering a pharmaceutically effective amount of baclofen to an individual suffering from insomnia.
Lynn Health Science Institute, Inc.


04/16/15
20150105466 
 Intrathecal baclofen pharmaceutical dosage forms with fewer degradation products patent thumbnailIntrathecal baclofen pharmaceutical dosage forms with fewer degradation products
The present invention relates generally to a sterile, particulate-free, stable intrathecal baclofen solution with less than 0.5% of 4-(4-chlorophenyl)-2-pyrrolidone, a degradation product. These solutions are stable under a variety of storage conditions and for extended periods of time.
Mallinckrodt Llc


02/12/15
20150045437 
 Transdermal delivery kits patent thumbnailTransdermal delivery kits
Provided are kits containing a base composition and an active pharmaceutical ingredient for transdermal delivery of active pharmaceutical ingredients. Examples of active pharmaceutical ingredients include amitriptyline, baclofen, cyclobenzaprine hcl, ibuprofen, lidocaine hcl, naproxen and tramadol, ketoprofen, diclofenac, phenylbutazone, mefenamic acid, flubiprofen, piroxicam, guaifenasin, prilocaine, bupivicaine, tetracaine, nifedipine, verapamil, orphenadrine, imipramine, ketamine, gabapentin, carbamazepine, menthol, capsaicin, clonidine, dexamethasone, dextromethorphan, testosterone, progesterone, and estrogens..
Asclemed Usa, Inc. Dba Enovachem Manufacturing


12/25/14
20140378440 
 Baclofen and acamprosate based therapy of neurological disorders patent thumbnailBaclofen and acamprosate based therapy of neurological disorders
The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and amyloid β toxicity. More specifically, the present invention relates to novel combinatorial therapies of alzheimer's disease, alzheimer's disease related disorders, amyotrophic lateral sclerosis, multiple sclerosis, parkinson's disease, huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury, based on baclofen and acamprosate combination..
Pharnext


12/18/14
20140371153 
 Method for administering omega-conopeptide patent thumbnailMethod for administering omega-conopeptide
The present invention is directed to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl 1, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound.
Jazz Pharmaceuticals International Limited


10/23/14
20140316007 
 Therapeutic combination of memantine and baclofen and pharmaceutical composition containing them patent thumbnailTherapeutic combination of memantine and baclofen and pharmaceutical composition containing them
The present invention relates to the combination of memantine and baclofen active ingredients, and also to the method for achieving body weight loss and thereby treating obesity and related co-morbidities by co-administration of baclofen and memantine.. .

10/02/14
20140296830 
 Methods of administering drugs in an implantable multi-chamber pump patent thumbnailMethods of administering drugs in an implantable multi-chamber pump
One embodiment of the present invention is a method for reducing pain using a multi chamber pump to separately administer multiple drugs. For example, one chamber may contain an omega conopeptide, such as ziconotide, and the other chamber or chambers may contain one or more other drugs, which may include of morphine, hydromorphone, fentanyl, sufentanil, bupivacaine, baclofen, clonidine, and buprenorphine, or their pharmaceutically acceptable salts thereof.

05/08/14
20140128355 
Baclofen solution for low-volume therapeutic delivery
A high concentration baclofen solution is provided suitable for therapeutic use in a medical setting. A high concentration solution of baclofen in multivalent physiological ion solution such as artificial cerebrospinal fluid is provided with concentrations of baclofen of 10 mg/ml.

04/17/14
20140107038 

Method for administering omega-conopeptide


The present invention is directed to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl 1, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound.

04/17/14
20140105973 

Method of treating a disease condition susceptible to baclofen therapy


The present invention discloses a method of treating a disease condition susceptible to baclofen therapy, said method comprising orally administering once-a-day in the evening a controlled release drug delivery system comprising baclofen or its pharmaceutically acceptable salt or its derivatives and pharmaceutically acceptable excipients.. .

03/06/14
20140066501 

Anhydrous and hemihydrate crystalline forms of an (r)-baclofen prodrug, methods of synthesis and methods of use


Crystalline (3r)-4-{[(1s)-2-methyl-1-(2-methylpropanoyloxy)propoxy]carbonylamino}-3-(4-chlorophenyl)butanoic acid anhydrate and crystalline (3r)-4-{[(1s)-2-methyl-1-(2-methylpropanoyloxy)propoxy]carbonylamino}-3-(4-chlorophenyl)butanoic acid hemihydrate, pharmaceutical compositions comprising such compounds, methods of making and methods of using the same are disclosed.. .

12/12/13
20130331451 

High concentration baclofen preparations


Stable aqueous solutions comprising concentrations of baclofen in the range of greater than 2.0 mg/ml up to about 10 mg/ml are disclosed. These solutions can be used as pharmaceuticals for parenteral or oral administration.

10/03/13
20130261186 

Methods of treating autism


Subjects having autism are treated with a composition that includes gamma-aminobutyric acid agonists. The gamma-aminobutyric acid agonist (gaba) can be a gaba(b) agonist, such as baclofen.

08/29/13
20130225499 

Method for administering omega-conopeptide


The present invention is directed to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound.

05/30/13
20130137670 

Zwitterion solution for low-volume therapeutic delivery


A formulation is provided that includes a volume of an aqueous multivalent physiological ion solution compatible with cerebrospinal fluid containing at least one divalent cation of magnesium or calcium, and at least one anion of carbonate or phosphate, and having a ph between 6.5 and 8.0. A zwitterionic therapeutic agent other than baclofen is dissolved the solution to achieve higher concentration or ease of solution and/or storage relative to therapeutic saline solutions of the same agent.

05/23/13
20130131176 

High concentration baclofen preparations


Stable aqueous solutions comprising concentrations of baclofen in the range of greater than 2.0 mg/ml up to about 10 mg/ml are disclosed. These solutions can be used as pharmaceuticals for parenteral or oral administration.

05/02/13
20130109755 

Baclofen formulations and methods for making same


Methods for preparing sterilized baclofen solutions include adjusting the ph to below a desired ph, and steam sterilizing the solution with adjusted ph, which results in the solution having the desired ph. Such solutions may also have low concentrations of 4-cpp.

04/18/13
20130096066 

Pharmaceutical formulation for reducing pain


The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound.

04/11/13
20130090307 

Baclofen and acamprosate based therapy of neurological disorders


The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and amyloid β toxicity. More specifically, the present invention relates to novel combinatorial therapies of multiple sclerosis, alzheimer's disease, alzheimer's disease related disorder, amyotrophic lateral sclerosis, parkinson's disease, huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury, based on baclofen and acamprosate combination..

04/04/13
20130085171 

Compounded transdermal pain management


The present embodiments relate to topically delivered medication (compounded) for treatment of pain, inflammation, muscle fatigue, spasms, and/or other ailments. A transdermal cream may provide the effective topical administration of multiple medications simultaneously.

04/04/13
20130085122 

Baclofen and acamprosate based therapy of neurological disorders


The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and amyloid β toxicity. More specifically, the present invention relates to novel combinatorial therapies of multiple sclerosis, alzheimer's disease, alzheimer's disease related disorder, amyotrophic lateral sclerosis, parkinson's disease, huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury, based on baclofen and acamprosate combination..

02/14/13
20130041026 

Anhydrous and hemihydrate crystalline forms of an (r)-baclofen prodrug, methods of synthesis and methods of use


Crystalline (3r)-4-{[(1s)-2-methyl-1-(2-methylpropanoyloxy)propoxy]carbonylamino}-3-(4-chlorophenyl)butanoic acid anhydrate and crystalline (3r)-4-{[(1s)-2-methyl-1-(2-methylpropanoyloxy)propoxy]carbonylamino}-3-(4-chlorophenyl)butanoic acid hemihydrate, pharmaceutical compositions comprising such compounds, methods of making and methods of using the same are disclosed.. .

01/10/13
20130012587 

Methods of treating autism


Subjects having autism are treated with a composition that includes gamma-aminobutyric acid agonists. The gamma-aminobutyric acid agonist (gaba) can be a gaba(b) agonist, such as baclofen..

01/10/13
20130012586 

Methods of treating fragile x syndrome


Subjects having fragile x syndrome are treated with a composition that includes gamma-aminobutyric acid agonists. The gamma-aminobutyric acid agonist (gaba) can be a gaba(b) agonist, such as baclofen, including racemic and r-baclofen..



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Baclofen topics: Ziconotide, Hydromorphone, Buprenorphine, Intrathecal, Acamprosate, Spinal Cord Injury, Multiple Sclerosis, Spinal Cord, Butyric Acid, Sufentanil, Pharmaceutically Acceptable Salts, Bupivacaine, Antioxidant, Pharmaceutical Formulation, Pharmaceutically Acceptable Salt

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