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Autologous

Autologous-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Gm-csf/cd40l vaccine and checkpoint inhibitor combination therapy
H. Lee Moffitt Cancer Center And Research Institute, Inc.
June 14, 2018 - N°20180162943

A method is disclosed for treating a cancer in a subject. The method comprises administering to the subject a composition comprising a therapeutically effective amount of a checkpoint inhibitor and a therapeutically effective amount of a tumor vaccine.
Using autologous mesenchymal stem cells to treat multiple system atrophy
Mayo Foundation For Medical Education And Research
June 14, 2018 - N°20180161374

This document provides methods and materials for treating multiple system atrophy in a mammal. Specifically, the methods comprises intrathecally administering to the mammal a composition comprising autologous mesenchymal stem cells (e.g.
Method of progenitor cell isolation from different organs by natural destruction of extracellular matrix
Reelabs Private Limited, A Company Incorporated Under Provisions Of The Companies Act 1956
May 03, 2018 - N°20180119093

The present invention is directed to novel methods comprising the isolation of viable fetal progenitor cells from organs of aborted fetus. The invention comprises the use of natural proteolytic, collagenolytic and fibrinolytic activity of autologous abortive placenta tissue extract..
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Method for three dimensional printing artificial skin
3d Global Biotech Inc.
April 19, 2018 - N°20180105781

The present invention discloses a method for three dimensional printing artificial skin. The method comprises the following steps of: printing a dermis layer by a hydrogel combined with an autologous dermal cell and; printing an epidermis layer on the dermis layer by a hydrogel combined with an autologous kerationocytes cell; implanting a plurality of progenitor cells for sweat glands and ...
Systems and methods for autologous biological therapeutics
Greyledge Technologies, Llc
April 12, 2018 - N°20180100133

An autologous cell concentrating system and method are disclosed. The system has a blood separation component, a first vessel, a second vessel, a first valve, a second valve, and a concentration and flow logic and control component.
Composition and methods of genome editing of b-cells
Dana-farber Cancer Institute, Inc.
April 05, 2018 - N°20180094243

The present invention provides methods compositions and methods of preparing autologous b-cells that secrete a monoclonal of interest useful in immunotherapy.. .
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Dna vector and transformed tumor cell vaccines
Morphogenesis, Inc.
March 29, 2018 - N°20180085448

Customized whole cell cancer vaccines can be produced from autologous (ex vivo or in situ) or allogeneic human or veterinary patient cell lines. Cells are transformed with s.
Cell maintainer for autologous cell therapy production
Thrive Bioscience, Inc.
March 22, 2018 - N°20180079999

In some aspects, the invention relates to automated cell culture incubators and their methods of use. In one aspect, the disclosure provides cell culture incubators having an airlock chamber, a storage chamber and/or an internal chamber.
Furin-knockdown and gm-csf-augmented (fang) cancer vaccine
Gradalis, Inc.
March 15, 2018 - N°20180073038

Compositions and methods for cancer treatment are disclosed herein. More specifically, the present invention describes an autologous cancer vaccine genetically modified for furin knockdown and gm-csf expression.
Autologous cell multidimensional molding apparatus
3d Global Biotech Inc.
March 15, 2018 - N°20180072973

The present invention discloses an autologous cell multidimensional molding apparatus, which can customize an artificial implant by using an autologous cell. The autologous cell multidimensional molding apparatus comprises a barotropic room, an autologous cell culturing module, a supplying module, a multi-axis molding module, and an implant saving module.
Cell scaffold constructs
Inregen
March 15, 2018 - N°20180071074

The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.. .
Methods to accelerate wound healing in diabetic subjects
Joslin Diabetes Center, Inc.
March 08, 2018 - N°20180066327

Methods of accelerating wound healing in diabetic subjects using autologous cell grafts treated to specifically inhibit protein kinase c delta (pkc6), as well as cells and compositions for use in these methods. Provided herein are methods for preparing cells for application to a wound in a diabetic subject.
Methods for isolating and proliferating autologous cancer antigen-specific cd8+ t cells
National Cancer Center
March 01, 2018 - N°20180057793

Provided is a method for isolating and proliferating autologous cancer antigen-specific cd8+t cells, and more particularly, a method for selecting an epitope recognized by cd8+ t cells from autologous cancer antigens present in blood of individual cancer patients; and isolating autologous cancer antigen-specific cd8+ t cells by using a peptide of the selected epitope, and a method of massively ...
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Ex vivo liquid biopsy
Helomics Corporation
February 22, 2018 - N°20180052168

Embodiments disclosed herein provide in vitro methods for use in the culture and biochemical analysis of normal or malignant cells in autologous, allogeneic, and xenogeneic fluids and the biomarkers secreted from those cells over time and in response to various changing conditions. The methods disclosed herein provide a clinical diagnostic and research platform that provides for the study of fundamental ...
Surgical wound healing composition and method of applying the same
February 22, 2018 - N°20180050066

Compositions and methods are disclosed for improving the healing of surgical wounds, and specifically for improving the survival rate, color retention rate, density, and scarring rate of a hair follicular graft following a hair transplantation surgery. The composition may be a suspension for injection proximal to the surgical graft recipient site, with the suspension comprising 0.4-0.5 ml of a suspension ...
Systems and methods to reduce injury in the heart
Cardiac Pacemakers, Inc.
February 15, 2018 - N°20180043071

This document discusses, among other things, systems and methods to reduce ischemic or metabolic injury to a patient's heart. A system to reduce ischemic or metabolic injury to a patient's heart may include a pulse generator for generating electrical pulses or shock, a pacing lead with at least one pacing electrode configured to deliver electrical pulses received from the pulse ...
Human cord blood as a source of neural tissue repair of the brain and spinal ...
Saneron Ccel Therapeutics, Inc.
February 15, 2018 - N°20180042968

The present invention relates to the use of umbilical cord blood cells from a donor or patient to provide neural cells which may be used in transplantation. The isolated cells according to the present invention may be used to effect autologous and allogeneic transplantation and repair of neural tissue, in particular, tissue of the brain and spinal cord and to ...
Percutaneous cannula assembly
Adimend Biosciences, Llc
February 15, 2018 - N°20180042590

The dual syringe with percutaneous cannula is a medical device for harvesting and transferring cells for autologous transplantation without the requirement of a surgical setting or ambulatory care. The dual syringe is a closed sterile system that allows for the harvesting syringe to harvest the cells/tissue from a first location of a patient which is then centrifuged to aggregate ...
Method for harvesting and transplanting cells
Adimend Biosciences, Llc
February 15, 2018 - N°20180042589

The dual syringe with percutaneous cannula is a medical device for harvesting and transferring cells for autologous transplantation without the requirement of a surgical setting or ambulatory care. The dual syringe is a closed sterile system that allows for the harvesting syringe to harvest the cells/tissue from a first location of a patient which is then centrifuged to aggregate ...
Methods and compositions based on diphtheria toxin-interleukin-3 conjugates
Scott & White Memorial Hospital
January 25, 2018 - N°20180022788

The present invention provides methods for inhibiting interleukin-3 receptor-expressing cells, and, in particular, inhibiting the growth of such cells by using a diphtheria toxin-human interleukin-3 conjugate (dt-il3) that is toxic to cells expressing the interleukin-3 receptor. In preferred embodiments, the dt-il3 conjugate is a fusion protein comprising amino acids 1-388 of diphtheria toxin fused via a peptide linker to full-length, ...
System for generating high concentration factors for low cell density suspensions
Flodesign Sonics, Inc.
January 18, 2018 - N°20180016570

Acoustophoretic devices and methods for concentrating targeted biological cells in a reduced volume using multi-dimensional acoustic standing waves are disclosed. The methods include flowing a mixture of a host fluid and the biological cells through an acoustophoretic device.
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