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Autologous patents



      
           
This page is updated frequently with new Autologous-related patents. Subscribe to the Autologous RSS feed to automatically get the update: related Autologous RSS feeds.

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Date/App# patent app List of recent Autologous-related patents
04/17/14
20140107699
 Active loaded fixation devices patent thumbnailActive loaded fixation devices
The present disclosure relates to methods for producing, including intra-operatively obtaining, a fixation device, and fixation devices produced thereby, containing an autologous cell concentrate from a physiological solution, wherein the cell concentrate is isolated without the need for centrifugation.. .
04/10/14
20140101786
 Generation of autologous t-cells in mice patent thumbnailGeneration of autologous t-cells in mice
The invention provides an animal model and methods of generating large numbers of diverse, functional, naïve t cells in mice using bone marrow cells from adult donors.. .
04/10/14
20140099383
 Topical dermal formulations patent thumbnailTopical dermal formulations
An autologous topical formulation containing conditioned medium obtained from culture of autologous fibroblasts has been developed. Unlike other topical formulations, it is autologous since it is derived solely from cells obtained by the person who is to use the formulation.
04/10/14
20140099287
 Plasma protein concentrate for cell delivery in regenerative applications patent thumbnailPlasma protein concentrate for cell delivery in regenerative applications
The invention is directed to concentrating autologously-derived plasma, using the concentrated plasma fluid to dilute the patient's cells and applying the combination of concentrated fluid with cells at a site of pathology or mixing the combination of concentrated fluid with cells with a particulate material like a bone void filler prior to placing the mixture at a site of pathology.. .
04/03/14
20140093482
 Methods and apparatuses for isolating and preparing stem cells patent thumbnailMethods and apparatuses for isolating and preparing stem cells
The present invention relates to a method of preparing a population of stem cells for autologous implantation to a subject. The cells are activated by irradiating the cells with one or more wavelengths of yellow and red and/or green light.
03/27/14
20140087469
 System and process for genetic and epigenetic treatment patent thumbnailSystem and process for genetic and epigenetic treatment
Transplantation of total or partial organs or tissues from one person to another creates severe immunologic problems and does not obtain a genetic rejuvenation, for example, of half the biological age of the donor's selected tissue. The invention permits, without a return to an embryonic stage, to develop an autologous and genetic rejuvenated (agr) tissue that can be grafted without graft rejection in the donor's body.
03/27/14
20140087002
 Autologous lymph node transfer in combination with vegf-c or vegf-d growth factor therapy to treat lymphedema and to improve reconstructive surgery patent thumbnailAutologous lymph node transfer in combination with vegf-c or vegf-d growth factor therapy to treat lymphedema and to improve reconstructive surgery
Materials and methods are provided to improve survival of lymph nodes and integration of lymph nodes into a lymphatic network, following lymph node transplantation. The treatment or prevention of lymphedema is also addressed.
03/13/14
20140071787
 Method and apparatus to create autologous clotting serum patent thumbnailMethod and apparatus to create autologous clotting serum
A clotting serum production device including a main chamber, an inlet housing, and an outlet port. The main chamber is defined by a first end wall, a second end wall opposite to the first end wall, and a side wall extending between the first end wall and the second end wall.
03/06/14
20140065629
 Methods of treating diseases patent thumbnailMethods of treating diseases
In one example, the present invention comprises deliberate tumor insult and sequencing of the t cell repertoire before and after the insult in order to detect and sequence the tcr alpha and beta loci of highly expanded t cell clonotypes. In some examples, this information is used in turn to create autologous genetically engineered t cells with tcr sequences that target the individual's tumor..
03/06/14
20140065098
 Method to augment immune system in response to disease or injury patent thumbnailMethod to augment immune system in response to disease or injury
In one example, the present invention comprises a deliberate insult or the recognition that an insult has occurred in a patient, which insult induces an immune recognition event. The t cell repertoire is catalogued from samples of the patient's lymphocytes from before and after the insult in order to detect and sequence the tcr alpha and beta loci of highly expanded t cell clonotypes.
03/06/14
20140065096
Cancer therapy by ex vivo activated autologous immune cells
Disclosed are therapeutic methods for ex-vivo activation of immune cells from a cancer patient for the purpose of inducing tumor regression and/or suppressing metastasis and/or tumor recurrence. In one embodiment mononuclear cells of a patient are isolated from peripheral blood and activated by a combination of innate immune system activators together with means allowing for t cell activation..
02/27/14
20140056842
Cellular therapeutic approaches to traumatic brain and spinal cord injury
The described invention provides cellular therapeutic approaches for treating a vascular insufficiency following a traumatic injury to head or spine that results in an injury to brain, spinal cord, or both by administering a therapeutic amount of an isolated, nonexpanded population of autologous mononuclear cells comprising a subpopulation of cd34+ cells, which further contains a subpopulation of potent sdf-1 mobile cd34+/cxcr-4 cells that have cxcr-4-mediated chemotactic activity.. .
02/20/14
20140051662
Treatment of multiple myeloma with masitinib
The present invention relates to the treatment of multiple myeloma, especially for the treatment of those patients with refractory or first relapsed multiple myeloma, and in particular patients with t(4;14) multiple myeloma, comprising administration of a tyrosine kinase inhibitor or a mast cell inhibitor, especially masitinib or a pharmaceutically acceptable salt thereof, administered in association with an additional care in multiple myeloma; for example, autologous stem-cell transplantation, targeted therapies, anti-myeloma agents such as alkylating agents, corticosteroids, or immunomodulatory agents, including bortezomib, lenalidomide, and dexamethasone.. .
02/06/14
20140037615
Materials and methods for designing autologous idiotype vaccines and treatment of b-cell malignancies
The present invention relates to compositions, kits, and methods for preparing an autologous idiotype vaccine, or autologous anti-idiotype vaccine, for treatment of a b-cell malignancy based on the isotype(s) (class(es)) of immunoglobulins expressed by the malignancy; methods for treating b-cell malignancies; and methods for selecting a treatment for a subject having a b-cell malignancy.. .
02/06/14
20140034567
Method and apparatus for producing autologous clotting components
A method and apparatus for obtaining various components of a multi-component material. Generally, a component of a whole blood sample may be concentrated from a patient and re-introduced to the same patient.
01/30/14
20140030806
Adoptive cell therapy with young t cells
The invention provides a method of promoting regression of a cancer in a mammal comprising (i) culturing autologous t cells; (ii) expanding the cultured t cells; (iii) administering to the mammal nonmyeloablative lymphodepleting chemotherapy; and (iv) after administering nonmyeloablative lymphodepleting chemotherapy, administering to the mammal the expanded t cells, wherein the t cells administered to the mammal are about 19 to about 35 days old and have not been screened for specific tumor reactivity, whereupon the regression of the cancer in the mammal is promoted.. .
01/30/14
20140030308
Implants and procedures for promoting autologous stem cell growth
A biologically engineered stent for treating patients suffering from acute myocardial infarction/ischemia. The stent is inserted in a vessel upstream to and proximal the damaged muscle/ischemic area.
01/23/14
20140024888
Method for complex phaloplasty using circumcised foreskin as autograft
Disclosed is a method for complex phalloplasty for widening a penis, using a circumcised foreskin as an autologous graft. In the method, a foreskin cut off by circumcision, conventionally discarded as waste, is implanted as an autograft in phalloplasty, whereby the penis can be widened..
01/23/14
20140023720
Enhanced autologous growth factor production and delivery system
Systems and methods for producing enhanced blood serum with concentrated growth factors and/or prophylactically and therapeutically active proteins. An autologous blood product is obtained from a donor and then incubated into a containment device (sterile container) that includes a source of cells or tissue (for example, autologous, allogeneic, or xenographic tissue, or combinations thereof).
01/16/14
20140018920
Lamina implant and method
A prosthetic implant for restoring lamina after a laminectomy. The implant is generally a lamina-sized construct having a hollow interior.
01/16/14
20140017785
Methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts
The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them..
01/16/14
20140017783
Non-enzymatic method for isolating human adipose-derived stromal stem cells
A simple method was developed to extract adipose-derived stromal stem cells (ascs) without using enzymatic digestion of the collagen in adipose tissue. The resulting ascs isolated by the simple wash method have lower levels of cd34 expression, a hematopoietic stem cell marker, as compared to ascs isolated using conventional enzymatic digestion using collagenase.
01/09/14
20140010801
Compositions and methods for restoring or rejuvenating stem/progenitor cell function
This invention relates to the use of autologous stem/progenitor cells to restore or rejuvenate adult stem cell function in a mammal, wherein the restoration or rejuvenating extends lifespan and/or improves health of the mammal. In addition, the invention also relates to compositions containing one or more regulatory factors secreted or released from isolated mammalian stem/progenitor cells and use of such compositions to extend lifespan and/or improve health of a mammal.
01/02/14
20140004153
Use of somatic mutations in the extracellular domain of transmembrane proteins in a patient's tumor as immunogens for active humoral immunotherapy of cancer
Methods of identifying tumor-specific mutations that can serve as b cell epitopes for the induction of autologous tumor-specific antibodies are disclosed. In some embodiments, the methods include: identifying a tumor-specific mutation in an expressed gene of a subject having cancer; determining that the mutation is in a region of an open reading frame predicted to encode an extracellular domain of a membrane protein; and identifying a corresponding mutant polypeptide encoded by the expressed gene comprising the tumor-specific mutation.
01/02/14
20140004133
Treatment method for relapsing-remitting multiple sclerosis
Disclosed is a method for treating relapsing-remitting multiple sclerosis in a patient by administering to the patient autologous, ex vivo-expanded cd4+cd25+foxp3+cd127lowt reg cells when the patient is in remission. Also disclosed is a method of inhibiting the activity of autoimmune, autologous cytotoxic t and b cells in a patient suffering from relapsing-remitting multiple sclerosis, comprising administering a therapeutically effective amount of autologous cd4+cd25−foxp3+cd127lowt reg cells to the patient..
12/19/13
20130337017
Fusion proteins of collagen-binding domain and parathyroid hormone
Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (pth) and parathyroid hormone related peptide (pthrp) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy.
12/19/13
20130336935
Compositions and methods for restoring or rejuvenating stem/progenitor cell function
This invention relates to the use of autologous stem/progenitor cells to restore or rejuvenate adult stem cell function in a mammal, wherein the restoration or rejuvenating extends lifespan and/or improves health of the mammal. In addition, the invention also relates to compositions containing one or more regulatory factors secreted or released from isolated mammalian stem/progenitor cells and use of such compositions to extend lifespan and/or improve health of a mammal.
12/05/13
20130323212
Treatment for chronic myocardial infarct
A method of treating chronic post-myocardial infarction including helical needle transendocardial delivery of autologous bone marrow (abm) mononuclear cells around regions of hypo or akinesia in chronic post-myocardial infarction (mi) patients. The treatment is safe and improves ejection fraction (ef)..
11/28/13
20130316011
Expanded utility of red cell-derived microparticles (rmp) for treatment of bleeding
Red blood cell membrane derived microparticles (rmp) are safe, economical, effective hemostatic agents in the treatment of a wide range of bleeding conditions and can, therefore, be considered as universal hemostatic agents. Effective rmp are produced from red blood cells using a high-pressure extrusion membrane shear process.
11/28/13
20130315860
Methods and compositions based on diphtheria toxin-interleukin-3 conjugates
The present invention provides methods for inhibiting interleukin-3 receptor-expressing cells, and, in particular, inhibiting the growth of such cells by using a diphtheria toxin-human interleukin-3 conjugate (dt-il3) that is toxic to cells expressing the interleukin-3 receptor. In preferred embodiments, the dt-il3 conjugate is a fusion protein comprising amino acids 1-388 of diphtheria toxin fused via a peptide linker to full-length, human interleukin-3.
11/14/13
20130303735
Method of treating a pathological syndrome and a pharmaceutical agent
Pharmaceutical agent for treating a pathological syndrome contains activated form of ultra-low doses of monoclonal, polyclonal or natural antibodies to an antigen, wherein said activated form is prepared by means of repeated consecutive dilution and external treatment, predominantly based on homeopathic technology, and said antigen is a substance or a drug acting as a direct cause of the pathological syndrome or involved in regulation of mechanisms of its formation. At that, activated forms of ultra-low doses of antibodies are raised against antigens of exogenous or endogenous origin, against autologous antigens, fetal antigens; anti-idiotypic antibodies are used too..
11/14/13
20130302312
Method of treating a pathological syndrome and a pharmaceutical agent
Pharmaceutical agent for treating a pathological syndrome contains activated form of ultra-low doses of monoclonal, polyclonal or natural antibodies to an antigen, wherein said activated form is prepared by means of repeated consecutive dilution and external treatment, predominantly based on homeopathic technology, and said antigen is a substance or a drug acting as a direct cause of the pathological syndrome or involved in regulation of mechanisms of its formation. At that, activated forms of ultra-low doses of antibodies are raised against antigens of exogenous or endogenous origin, against autologous antigens, fetal antigens; anti-idiotypic antibodies are used too..
11/14/13
20130302293
Compositions, cells, kits and methods for autologous stem cell therapy
Described herein are compositions, kits and methods for stimulating angiogenic functions of stem cells and/or progenitor cells having pro-angiogenic potential (e.g., endothelial progenitor cells (epcs), mesenchymal stem cells (mscs)) before transplantation (e.g., ex vivo cell therapy) based on the discovery that functional recovery of cd34+ cells from coronary artery disease (cad) patients is improved by transfection of antagomirs against one or more mirs of a plurality of mirs identified to be over-expressed in cells from cad patients. Described herein are methods to recover the functions of epcs isolated from patients with cardiovascular disease (e.g., cad or peripheral artery disease (pad)) by bioengineering the cells with antagomirs and/or premirs to specific micro-rnas.
11/14/13
20130300018
Polyhydroxyalkanoate medical textiles and fibers
Absorbable polyester fibers, braids, and surgical meshes with prolonged strength retention have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate.
11/14/13
20130299407
Systems and methods for preparing autologous fibrin glue
The invention provides a system for preparing an autologous solid-fibrin web suitable for regenerating tissue in a living organism. The system includes a sealed primary container containing a separation medium and a low-density high-viscosity liquid.
11/07/13
20130295061
Dosage unit formulations of autologous dermal fibroblasts
Dosage units consist of an autologous cell therapy product composed of fibroblasts grown for each individual to be treated. The suspension of autologous fibroblasts, grown from a biopsy of each individual's own skin using current good manufacturing practices (cgmp), and standard tissue culture procedures, is supplied in vials containing cryopreserved fibroblasts or precursors thereof, having a purity of at least 98% fibroblasts and a viability of at least 85%, for administration of from one to six ml, preferably two ml, of cells at a concentration of from 1.0-2.0×107 cells/ml.
10/31/13
20130287753
Compositions and methods for cartilage repair
Autologous compositions and methods are provided for cartilage repair in patients in need thereof. Some aspects include combinations of platelet-based materials with chondrogenesis inducing agents in the presence or absence of cell-based therapies..
10/17/13
20130274138
Gene signatures for prediction of therapy-related myelodysplasia and methods for identification of patients at risk for development of the same
In one embodiment, a gene expression signature for predicting risk of developing therapy-related myelodysplasia or acute myeloid leukemia (t-mds/aml) after autologous hematopoietic cell transplantation (ahct) is provided. In another embodiment, a method for predicting a risk for development of t-mds/aml after ahct is provided.
10/17/13
20130274114
Multipotent stem cell-based culture systems and models
This invention generally relates to multipotent stem cell-based research tools. More particularly, the present invention relates to culture systems and 3-dimensional tissue models that may be used for identifying agents useful for treating diseases and conditions and that are suitable for high throughput screening applications.
10/03/13
20130261676
Bone anchor
A biocompatible implantable bone anchor is provided that has a threaded first portion that engages and anchors into a bone. The implant also has a neck region extending from the first portion adapted to promote autologous cell growth thereon at an interface of the bone and one or more epidermal or gum layers, the neck region having a plurality of channels extending about the neck region.
10/03/13
20130259919
Surgical device for skin therapy or testing
A device, and method of making the device, capable of therapeutic treatment and/or for in vitro testing of human skin. The device may be used on skin wounds for burned, injured, or diseased skin, and provides structures and functions as in normal uninjured skin, such as barrier function, which is a definitive property of normal skin.
10/03/13
20130259845
Treatment of premature birth complications
The present invention provides methods of treating one or more complications of premature birth suffered by premature infants, comprising administering to the premature infant umbilical cord blood stem cells and, optionally, placental stem cells. The present invention also provides methods of combining and administering, and compositions comprising, umbilical cord blood stem cells, particularly autologous cord blood cells, and placental stem cells for the treatment of premature infants..
09/26/13
20130253553
Percutaneous methods and apparatus for creating native tissue venous valves
Percutaneous methods and apparatuses for forming a venous valve from autologous tissue. A catheter having a retractable dissecting system received therein is delivered to a target location where a new venous valve is to be created.
09/26/13
20130252278
Process of application procedures through cell biology for animal use
Process of application procedures through cell biology for animal use, the invention is applied to the field of cell biology, specifically the isolation, in vitro culture, cryopreservation, cell differentiation and application of mesenchymal stem cells derived from adipose tissue of animals for autologous cell therapy purposes. Strategically seeks to establish, from the adipose tissue collection, all events resulting in schematic form, in order to obtain a homogeneous extract of mesenchymal stem cells.
09/19/13
20130244244
Predicting allergic reactions
This present invention provides a method of predicting immunogenicity and hypersensitivity or allergic reactions to chemical compounds, therapeutics, cosmetics and other chemical compositions. The method uses an in vitroassay employing autologous bloodderived cells and an autologous cultured skin biopsy and is of particular utility in the identification and prediction of skin sensitizers that cause allergic contact dermatitis..
09/12/13
20130236437
Compositions, kits and methods for treatment of cardiovascular, immunological and inflammatory diseases
Compositions, kits, cells and methods for treating cardiovascular (e.g., myocardial ischemia and heart failure), immunological, and inflammatory diseases or disorders involve the use of the mature and precursor sequences of micrornas 142-5p, 142-3p, 17-5p, 17-3p, 374, and 20a, and of antisense molecules complementary to these sequences, to manipulate processes relevant to, for example, the cardiac response to stress, including survival signaling, angiogenesis, stem cell differentiation along muscle or vascular lineages, and repression or promotion of cardiac myocyte growth. Also described are methods to treat cardiovascular, immunological and inflammatory diseases by engineering cells containing specific micro-rnas or antagomirs against specific mrnas.
08/29/13
20130224160
Treatment of vocal cords with autologous dermal fibroblast formulation
Dosage units consist of an autologous cell therapy product composed of fibroblasts grown for each individual to be treated for augmentation or regeneration of vocal cords. The suspension of autologous fibroblasts, grown from a biopsy of each individual's own buccal mucosa or skin using current good manufacturing practices (cgmp) and standard tissue culture procedures, is supplied in vials containing cryopreserved fibroblasts or precursors thereof, having a purity of at least 98% fibroblasts and a viability of at least 85%, for administration of from one to six ml, preferably two ml administered three times approximately three to six weeks apart, of cells at a concentration of from 1.0-2.0×107 cells/ml..
08/22/13
20130216601
Three-dimensional bone implant and method for producing same
A method for ex vivo production of a three-dimensional bone implant adapted for implantation to a patient, implants produced by such a method, and uses of such implants. The method comprises disposing differentiated osteoblasts on a matrix support comprising at least one of collagen, calcium phosphate, calcium sulfate and tricalcium phosphate; contacting the differentiated osteoblasts on the matrix with autologous blood serum from the patient, comprising at least one of a growth factor and a cytokine; and disposing the differentiated osteoblasts on the matrix support and the medium in a bioreactor, in which production of the bone implant is performed..
08/01/13
20130197470
Adaptable perioperative cell-salvage system and methods and disposable units for same
A blood-collection system configured to permit selection of either collection and disposal of shed blood from a patient or collection and processing of shed blood for autologous transfusion back to the patient includes an automated blood-processing machine. The system may also include a blood-collection reservoir, a separation chamber, and a fluid conduit.
08/01/13
20130195958
Process for the production of patches or derssings of autologous skin through cultivation of autologous keratinocytes and fibroblasts with autologous serum for the generation of skin
The process in general is based on taking a sample of skin and a sample of blood from the patient and based on these two elements skin is cultured, being placed on a collagen patch to produce a dressing which is subsequently placed on the patient requiring same.. .
07/25/13
20130190679
Bronchoscopic lung volume reduction method
A method of minimally invasively reducing a volume of a hyper-inflated target section of diseased lung comprising the steps of introducing a bronchoscope into a patient's airway to a position adjacent the target section and equilibrating air within the target section with atmospheric air to at least partially deflate the target lung section; injecting an inflammation-causing substance into the target section to precipitate adhesion of the walls within the target lung section, preventing substantial re-inflation of the target section by occluding an airway upstream of the target section for a period of time, and removing the airway occlusion after the target section has substantially permanently been reduced in volume. The injected substance can be autologous blood or a constituent thereof..
07/25/13
20130189780
Reprogramming compositions
The present invention provides compositions and methods of using the compositions to alter the developmental potency of a cell. The present invention provides in vivo and ex vivo cell reprogramming or dedifferentiation methods suitable for autologous cell therapy and regenerative medicine..
07/25/13
20130189310
Autologous cancer cell vaccine
An autologous cancer cell vaccine comprises cancer cells that express both mhci and mhcii on their cell surface. The mhci presents a cancer antigen and the mhcii presents a non-self antigen..
07/04/13
20130173015
Cell scaffold constructs
The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.. .
06/06/13
20130144300
Applicator kit
An applicator and applicator kit for particulate bone replacement materials, autologous or heterologous cancellous bone, demineralised bone matrix. The applicator (1) contains a hollow tube (12) including on one end a bladed shutter.
05/23/13
20130130381
Method for obtaining a population of stromal progenitor cells
The present invention relates to a technique for obtaining stromal progenitor cells (spc) from adipose tissue (at) using incubation of very small volumes of at with an enzyme solution, that can obtain spc for autologous spc-based medical applications to a greater number of individuals, possibly having a lower body mass index (b.m.i), i.e. Lower than 18.5..
05/16/13
20130121974
Methods of making enhanced, autologous fat grafts
Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient.
05/02/13
20130108593
Mesenchymal stem cell isolation and transplantation method and system to be used in a clinical setting
A system and method for the percutaneous, autologous transplantation of mesenchymal stem cells and progenitor helper cells (phc) from bone marrow to degenerated intervertebral discs or joints. This method is designed to be used by operating room staff in a clinical setting to isolate a mesenchymal stem cell population and phc during the same surgical procedure as transplantation.
05/02/13
20130108588
Multipotent stem cell cultures
The invention provides methods for propagation of multipotent stem cells from human skin fibroblast samples using an appropriate medium, such as an amniotic fluid medium (afm), and subsequent differentiation of the cells into cells of any of the three germ layers. The invention also provides methods of differentiating and making various tissues from multipotent cells in skin fibroblasts cultures that are capable of in vitro differentiation and that the cells are useful as a source of in vivo gene and/or autologous cell therapy.
04/25/13
20130102073
Methods for making and using reprogrammed human somatic cell nuclei and autologous and isogenic human stem cells
Activated human embryos produced by therapeutic cloning can give rise to human totipotent and pluripotent stem cells from which autologous cells for transplantation therapy are derived. The present invention provides methods for producing activated human embryos that can be used to generate totipotent and pluripotent stem cells from which autologous cells and tissues suitable for transplantation can be derived.
04/18/13
20130097725
Soybean nodulation factor receptor proteins, encoding nucleic acids and uses therefor
The invention provides gmnfr1α, gmnfr1β, gmnfr5α, and gmnfr5β soybean nodulation factor receptor proteins, a receptor complex, and encoding nucleic acids. Also provided are gmnfr1α, gmnfr1β, gmnfr5α, and gmnfr5β promoters, which may be useful for expressing autologous or heterologous sequences in plants, such as soybean.
04/18/13
20130095060
Pharmaceutical composition for promoting arteriogenesis, and preparation method and applications for the same
The present invention relates to a pharmaceutical composition for promoting arteriogenesis, and preparation method and applications of the same, wherein said pharmaceutical composition comprises an effective amount of a drug, and a peptide hydrogel, and it forms a microenvironment for autologous cell recruitment and tissue regeneration.. .
04/04/13
20130084341
Compositions and methods to promote implantation and engrafment of stem cells
Tissue repair in-vivo depends on acute inflammation, but in many clinical situations the other major components of healing such as blood supply, anabolic hormones, growth factors, and stem cells are lacking. This invention includes compositions consisting of an agent which induces an inflammatory healing response combined with an autologous platelet lysate at a specific concentration which may have demonstrated in-vitro abilities to expand autologous tissue repair cells..
03/28/13
20130079699
Method of draining autologous bodily fluid into intraosseus space
A method for draining autologeous biological fluid includes positioning a catheter to receive the autologeous biological fluid from a selected site in a mammalian body with the end of the catheter adapted to receive such fluid. An output end of the catheter is positioned into the intraosseus space.
03/28/13
20130079292
Cyclic peptides binding cxcr4 receptor and relative medical and diagnostic uses
The present invention relates to the identification of new peptides and peptidomimetics which bind the cxcr4 receptor, capable of forming complexes with receptors for chemokines, in particular with cxcr4. The invention also relates to the use of these peptides for the treatment, prevention and diagnosis of diseases which involve chemokine receptors (i.e.
03/28/13
20130078819
Method for cleaning & passivating gallium arsenide surface autologous oxide and depositing al2o3 dielectric
The present invention belongs to the technical field of semiconductor materials and specifically relates to a method for cleaning & passivizing gallium arsenide (gaas) surface autologous oxide and depositing an al2o3 dielectric. This method includes: use a new-type of sulfur passivant to react with the autologous oxide on the gaas surface to clean it and generate a passive sulfide film to separate the gaas from the outside environment, thus preventing the gaas from oxidizing again; further cleaning the residuals such as autologous oxides and sulfides on the gaas surface through the pretreatment reaction of the reaction source trimethyl aluminum (tma) of the al2o3 ald with the gaas surface, and then deposit high-quality al2o3 dielectric through ald as the gate dielectric which fully separates the gaas from the outside environment.
03/28/13
20130078279
Furin-knockdown and gm-csf-augmented (fang) cancer vaccine
Compositions and methods for cancer treatment are discloses herein. More specifically the present invention describes an autologous cancer vaccine genetically modified for furin knockdown and gm-csf expression.


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Autologous topics: Autologous, Stem Cells, Differentiation, Fibroblast, Cell Therapy, Transplant, Cell Differentiation, Tissue Engineering, Myeloid Leukemia, Gene Expression, Acute Myeloid Leukemia, Complication, Umbilical Cord, Premature Birth, Premature Infant

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