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Autologous patents



      
           
This page is updated frequently with new Autologous-related patent applications. Subscribe to the Autologous RSS feed to automatically get the update: related Autologous RSS feeds. RSS updates for this page: Autologous RSS RSS


Date/App# patent app List of recent Autologous-related patents
08/14/14
20140228812
 Method for reducing tumors and transforming cancer cells patent thumbnailMethod for reducing tumors and transforming cancer cells
This invention is related to a phenol-quinone therapy that shrinks tumors and transforms cancer cells. The therapy include four phases.
08/14/14
20140227339
 Regenerative tissue grafts and methods of making same patent thumbnailRegenerative tissue grafts and methods of making same
A graft containing a scaffold that includes a matrix in which are positioned mesenchymal progenitor cells (mpcs) has the capacity to substantially improve wound healing, including wounds resulting from injury to nerve, bone and vascular tissue. Mpcs can be harvested from debrided muscle tissue following orthopaedic trauma.
08/07/14
20140220682
 Isolation, expansion and use of autologous pluripotent stem cells patent thumbnailIsolation, expansion and use of autologous pluripotent stem cells
The present invention relates to methods of isolating and culturing autologous pluripotent stem (aps) cells. The present invention also provides isolated aps cells, populations of aps cells and cultures of aps cells.
08/07/14
20140219980
 Treatment for mitochondrial neurogastrointestinal encephalomyopathy (mngie) patent thumbnailTreatment for mitochondrial neurogastrointestinal encephalomyopathy (mngie)
The invention provides a method of treating mitochondrial neurogastrointestinal encephalomyopathy (mngie) in a patient, comprising administering to the patient autologous erythrocytes that contain thymidine phosphorylase and are free of animal proteins other than proteins derived from the patient. The erythrocytes generally contain a low amount of endotoxin..
07/31/14
20140212391
 Vaginal laxity therapy utilizing cell-based bulking compositions patent thumbnailVaginal laxity therapy utilizing cell-based bulking compositions
The invention provides methods for the treatment of vaginal laxity which include delivering a cell-containing composition to the vagina. The composition can include fat tissue to provide a bulking effect to reduce the size of the vaginal opening.
07/24/14
20140207105
 Methods for effectively and rapidly desensitizing allergic patients patent thumbnailMethods for effectively and rapidly desensitizing allergic patients
Methods and compositions for delivering antigens to the lymphatic system in doses that desensitize patients to future exposure to antigens have been developed. Rapid desensitization is achieved by introducing small quantities of antigen into the lymphatic system.
07/24/14
20140205676
 Method of tissue repair using a composite material patent thumbnailMethod of tissue repair using a composite material
A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a young's modulus of at least 10 gpa. A calcium comprising salt is disposed in at least some of the pores.
07/24/14
20140205514
 Blood separating vessel for extracting autologous platelets, and apparatus for extracting autologous platelets patent thumbnailBlood separating vessel for extracting autologous platelets, and apparatus for extracting autologous platelets
Provided is a blood separating vessel for extracting autologous platelets, and an apparatus for extracting autologous platelets. The blood separating vessel for extracting autologous platelets comprises: a main body defining an internal space divided into an upper fluid chamber and a lower fluid chamber; an upper cover disposed to seal an upper portion of the upper fluid chamber; a lower cover disposed to seal a lower portion of the lower fluid chamber, the lower cover being coupled such that an outer peripheral surface of the lower cover is elevatable in a state of being in close contact along an inner peripheral surface of the lower fluid chamber by an external force applied upward; and a fluid collection part dividing the internal space into the upper fluid chamber and the lower fluid chamber and including a fluid passage protruding upward to communicate the upper fluid chamber with the lower fluid chamber..
07/10/14
20140194881
 Drill, drill cover, and surgical instrument for collecting autologous bone employing same patent thumbnailDrill, drill cover, and surgical instrument for collecting autologous bone employing same
A drill and drill cover and autogenous bone collector using the same are provided. The autogenous bone collector comprises s shaft unit connected to a driving device and a cutting unit which revolves and collects bone paticles of a patient.
06/26/14
20140178346
 Cellular compositions for tissue engineering patent thumbnailCellular compositions for tissue engineering
Cell compositions for tissue engineering are provided which contain a population of autologous, minimally passaged dermal fibroblasts in combination with a tissue engineering matrix or scaffold, or material forming a matrix or scaffold. In one embodiment, the population of fibroblasts is genetically engineered to secrete a therapeutic protein in an amount effective to induce tissue growth or tissue repair when the cell composition is transplanted into a subject in need thereof.
06/19/14
20140170176
Treatment method for relapsing-remitting multiple sclerosis
Disclosed is a method for treating relapsing-remitting multiple sclerosis in a patient by administering to the patient autologous, ex vivo-expanded cd4+cd25+foxp3+cd127low t reg cells when the patient is in remission. Also disclosed is a method of inhibiting the activity of autoimmune, autologous cytotoxic t and b cells in a patient suffering from relapsing-remitting multiple sclerosis, comprising administering a therapeutically effective amount of autologous cd4+cd25+foxp3+cd127low t reg cells to the patient..
06/12/14
20140162355
Formulations containing and kit for using adipose-derived stem cells and use thereof
Methods and kits for producing cellular fractions enriched in adipose derived stem cells. Methods are provided where adipose tissue obtained from liposuction is enzymatically treated using a solution containing collagenase and divalent cations prior to the application of traditional methods of stromal-vascular fraction isolation.
05/22/14
20140142718
Flexible tissue matrix and methods for joint repair
A synthetic, flexible tissue matrix and methods for repairing hyaline cartilage defects in a joint using the flexible tissue matrix are described. The flexible tissue matrix includes a high molecular weight polycaprolactone polymer entangled with a polysaccharide such as hyaluronic acid.
05/22/14
20140141047
Selection of platelet rich plasma components via mineral binding
Mineral coated devices and methods for delivering an autologous biological molecule using the mineral coated devices are disclosed. The mineral coated devices allow for the isolation and delivery of a biological molecule obtained from the same subject to avoid the safety concerns of current biological therapies obtained by recombinant methods and purification from animal sources.
05/15/14
20140135925
Breast reconstruction device and methods
A novel human breast implant and method for using the same comprising a bioabsorbable implant into which native, autologous vascularized tissue and autologous fat is placed and propagated within a patient's chest as a breast implant.. .
05/08/14
20140127171
Treatment of chronic post-traumatic encephalopathy
Methods of treating chronic post-traumatic encephalopathy (pte) using regenerative approaches is described. In one embodiment, molecules with capability of stimulating endogenous neural stem cells is provided.
04/24/14
20140114070
Compounds that expand hematopoietic stem cells
The present invention relates to compounds and compositions for expanding the number of cd34+ cells for transplantation. The invention further relates to a cell population comprising expanded hematopoietic stem cells (hscs) and its use in autologous or allogeneic transplantation for the treatment of patients with inherited immunodeficient and autoimmune diseases and diverse hematopoietic disorders to reconstitute the hematopoietic cell lineages and immune system defense..
04/24/14
20140112894
Autologous cells on a support matrix for tissue repair
The present invention relates to a method for the effective treatment of tissue defects and for tissue regeneration. The method includes seeding autologous cells on a support matrix and implanting the cell-seeded support matrix into a site of transplantation.
04/24/14
20140112891
Autologous human adult pluripotent very small embryonic-like (hvsel) stem cell regeneration of bone and cartilage
The invention provides methods and compositions for the repair or regeneration of osteochondral tissue. The methods and compositions provide an effective amount of isolated differentiable human very small embryonic like stem cells (hvsels) sufficient for regeneration or repair of an osteochondral tissue.
04/17/14
20140107699
Active loaded fixation devices
The present disclosure relates to methods for producing, including intra-operatively obtaining, a fixation device, and fixation devices produced thereby, containing an autologous cell concentrate from a physiological solution, wherein the cell concentrate is isolated without the need for centrifugation.. .
04/10/14
20140101786
Generation of autologous t-cells in mice
The invention provides an animal model and methods of generating large numbers of diverse, functional, naïve t cells in mice using bone marrow cells from adult donors.. .
04/10/14
20140099383
Topical dermal formulations
An autologous topical formulation containing conditioned medium obtained from culture of autologous fibroblasts has been developed. Unlike other topical formulations, it is autologous since it is derived solely from cells obtained by the person who is to use the formulation.
04/10/14
20140099287
Plasma protein concentrate for cell delivery in regenerative applications
The invention is directed to concentrating autologously-derived plasma, using the concentrated plasma fluid to dilute the patient's cells and applying the combination of concentrated fluid with cells at a site of pathology or mixing the combination of concentrated fluid with cells with a particulate material like a bone void filler prior to placing the mixture at a site of pathology.. .
04/03/14
20140093482
Methods and apparatuses for isolating and preparing stem cells
The present invention relates to a method of preparing a population of stem cells for autologous implantation to a subject. The cells are activated by irradiating the cells with one or more wavelengths of yellow and red and/or green light.
03/27/14
20140087469
System and process for genetic and epigenetic treatment
Transplantation of total or partial organs or tissues from one person to another creates severe immunologic problems and does not obtain a genetic rejuvenation, for example, of half the biological age of the donor's selected tissue. The invention permits, without a return to an embryonic stage, to develop an autologous and genetic rejuvenated (agr) tissue that can be grafted without graft rejection in the donor's body.
03/27/14
20140087002
Autologous lymph node transfer in combination with vegf-c or vegf-d growth factor therapy to treat lymphedema and to improve reconstructive surgery
Materials and methods are provided to improve survival of lymph nodes and integration of lymph nodes into a lymphatic network, following lymph node transplantation. The treatment or prevention of lymphedema is also addressed.
03/13/14
20140071787
Method and apparatus to create autologous clotting serum
A clotting serum production device including a main chamber, an inlet housing, and an outlet port. The main chamber is defined by a first end wall, a second end wall opposite to the first end wall, and a side wall extending between the first end wall and the second end wall.
03/06/14
20140065629
Methods of treating diseases
In one example, the present invention comprises deliberate tumor insult and sequencing of the t cell repertoire before and after the insult in order to detect and sequence the tcr alpha and beta loci of highly expanded t cell clonotypes. In some examples, this information is used in turn to create autologous genetically engineered t cells with tcr sequences that target the individual's tumor..
03/06/14
20140065098
Method to augment immune system in response to disease or injury
In one example, the present invention comprises a deliberate insult or the recognition that an insult has occurred in a patient, which insult induces an immune recognition event. The t cell repertoire is catalogued from samples of the patient's lymphocytes from before and after the insult in order to detect and sequence the tcr alpha and beta loci of highly expanded t cell clonotypes.
03/06/14
20140065096
Cancer therapy by ex vivo activated autologous immune cells
Disclosed are therapeutic methods for ex-vivo activation of immune cells from a cancer patient for the purpose of inducing tumor regression and/or suppressing metastasis and/or tumor recurrence. In one embodiment mononuclear cells of a patient are isolated from peripheral blood and activated by a combination of innate immune system activators together with means allowing for t cell activation..
02/27/14
20140056842
Cellular therapeutic approaches to traumatic brain and spinal cord injury
The described invention provides cellular therapeutic approaches for treating a vascular insufficiency following a traumatic injury to head or spine that results in an injury to brain, spinal cord, or both by administering a therapeutic amount of an isolated, nonexpanded population of autologous mononuclear cells comprising a subpopulation of cd34+ cells, which further contains a subpopulation of potent sdf-1 mobile cd34+/cxcr-4 cells that have cxcr-4-mediated chemotactic activity.. .
02/20/14
20140051662
Treatment of multiple myeloma with masitinib
The present invention relates to the treatment of multiple myeloma, especially for the treatment of those patients with refractory or first relapsed multiple myeloma, and in particular patients with t(4;14) multiple myeloma, comprising administration of a tyrosine kinase inhibitor or a mast cell inhibitor, especially masitinib or a pharmaceutically acceptable salt thereof, administered in association with an additional care in multiple myeloma; for example, autologous stem-cell transplantation, targeted therapies, anti-myeloma agents such as alkylating agents, corticosteroids, or immunomodulatory agents, including bortezomib, lenalidomide, and dexamethasone.. .
02/06/14
20140037615
Materials and methods for designing autologous idiotype vaccines and treatment of b-cell malignancies
The present invention relates to compositions, kits, and methods for preparing an autologous idiotype vaccine, or autologous anti-idiotype vaccine, for treatment of a b-cell malignancy based on the isotype(s) (class(es)) of immunoglobulins expressed by the malignancy; methods for treating b-cell malignancies; and methods for selecting a treatment for a subject having a b-cell malignancy.. .
02/06/14
20140034567
Method and apparatus for producing autologous clotting components
A method and apparatus for obtaining various components of a multi-component material. Generally, a component of a whole blood sample may be concentrated from a patient and re-introduced to the same patient.
01/30/14
20140030806
Adoptive cell therapy with young t cells
The invention provides a method of promoting regression of a cancer in a mammal comprising (i) culturing autologous t cells; (ii) expanding the cultured t cells; (iii) administering to the mammal nonmyeloablative lymphodepleting chemotherapy; and (iv) after administering nonmyeloablative lymphodepleting chemotherapy, administering to the mammal the expanded t cells, wherein the t cells administered to the mammal are about 19 to about 35 days old and have not been screened for specific tumor reactivity, whereupon the regression of the cancer in the mammal is promoted.. .
01/30/14
20140030308
Implants and procedures for promoting autologous stem cell growth
A biologically engineered stent for treating patients suffering from acute myocardial infarction/ischemia. The stent is inserted in a vessel upstream to and proximal the damaged muscle/ischemic area.
01/23/14
20140024888
Method for complex phaloplasty using circumcised foreskin as autograft
Disclosed is a method for complex phalloplasty for widening a penis, using a circumcised foreskin as an autologous graft. In the method, a foreskin cut off by circumcision, conventionally discarded as waste, is implanted as an autograft in phalloplasty, whereby the penis can be widened..
01/23/14
20140023720
Enhanced autologous growth factor production and delivery system
Systems and methods for producing enhanced blood serum with concentrated growth factors and/or prophylactically and therapeutically active proteins. An autologous blood product is obtained from a donor and then incubated into a containment device (sterile container) that includes a source of cells or tissue (for example, autologous, allogeneic, or xenographic tissue, or combinations thereof).
01/16/14
20140018920
Lamina implant and method
A prosthetic implant for restoring lamina after a laminectomy. The implant is generally a lamina-sized construct having a hollow interior.
01/16/14
20140017785
Methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts
The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them..
01/16/14
20140017783
Non-enzymatic method for isolating human adipose-derived stromal stem cells
A simple method was developed to extract adipose-derived stromal stem cells (ascs) without using enzymatic digestion of the collagen in adipose tissue. The resulting ascs isolated by the simple wash method have lower levels of cd34 expression, a hematopoietic stem cell marker, as compared to ascs isolated using conventional enzymatic digestion using collagenase.
01/09/14
20140010801
Compositions and methods for restoring or rejuvenating stem/progenitor cell function
This invention relates to the use of autologous stem/progenitor cells to restore or rejuvenate adult stem cell function in a mammal, wherein the restoration or rejuvenating extends lifespan and/or improves health of the mammal. In addition, the invention also relates to compositions containing one or more regulatory factors secreted or released from isolated mammalian stem/progenitor cells and use of such compositions to extend lifespan and/or improve health of a mammal.
01/02/14
20140004153
Use of somatic mutations in the extracellular domain of transmembrane proteins in a patient's tumor as immunogens for active humoral immunotherapy of cancer
Methods of identifying tumor-specific mutations that can serve as b cell epitopes for the induction of autologous tumor-specific antibodies are disclosed. In some embodiments, the methods include: identifying a tumor-specific mutation in an expressed gene of a subject having cancer; determining that the mutation is in a region of an open reading frame predicted to encode an extracellular domain of a membrane protein; and identifying a corresponding mutant polypeptide encoded by the expressed gene comprising the tumor-specific mutation.
01/02/14
20140004133
Treatment method for relapsing-remitting multiple sclerosis
Disclosed is a method for treating relapsing-remitting multiple sclerosis in a patient by administering to the patient autologous, ex vivo-expanded cd4+cd25+foxp3+cd127lowt reg cells when the patient is in remission. Also disclosed is a method of inhibiting the activity of autoimmune, autologous cytotoxic t and b cells in a patient suffering from relapsing-remitting multiple sclerosis, comprising administering a therapeutically effective amount of autologous cd4+cd25−foxp3+cd127lowt reg cells to the patient..
12/19/13
20130337017
Fusion proteins of collagen-binding domain and parathyroid hormone
Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (pth) and parathyroid hormone related peptide (pthrp) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy.
12/19/13
20130336935
Compositions and methods for restoring or rejuvenating stem/progenitor cell function
This invention relates to the use of autologous stem/progenitor cells to restore or rejuvenate adult stem cell function in a mammal, wherein the restoration or rejuvenating extends lifespan and/or improves health of the mammal. In addition, the invention also relates to compositions containing one or more regulatory factors secreted or released from isolated mammalian stem/progenitor cells and use of such compositions to extend lifespan and/or improve health of a mammal.
12/05/13
20130323212
Treatment for chronic myocardial infarct
A method of treating chronic post-myocardial infarction including helical needle transendocardial delivery of autologous bone marrow (abm) mononuclear cells around regions of hypo or akinesia in chronic post-myocardial infarction (mi) patients. The treatment is safe and improves ejection fraction (ef)..
11/28/13
20130316011
Expanded utility of red cell-derived microparticles (rmp) for treatment of bleeding
Red blood cell membrane derived microparticles (rmp) are safe, economical, effective hemostatic agents in the treatment of a wide range of bleeding conditions and can, therefore, be considered as universal hemostatic agents. Effective rmp are produced from red blood cells using a high-pressure extrusion membrane shear process.
11/28/13
20130315860
Methods and compositions based on diphtheria toxin-interleukin-3 conjugates
The present invention provides methods for inhibiting interleukin-3 receptor-expressing cells, and, in particular, inhibiting the growth of such cells by using a diphtheria toxin-human interleukin-3 conjugate (dt-il3) that is toxic to cells expressing the interleukin-3 receptor. In preferred embodiments, the dt-il3 conjugate is a fusion protein comprising amino acids 1-388 of diphtheria toxin fused via a peptide linker to full-length, human interleukin-3.
11/14/13
20130303735
Method of treating a pathological syndrome and a pharmaceutical agent
Pharmaceutical agent for treating a pathological syndrome contains activated form of ultra-low doses of monoclonal, polyclonal or natural antibodies to an antigen, wherein said activated form is prepared by means of repeated consecutive dilution and external treatment, predominantly based on homeopathic technology, and said antigen is a substance or a drug acting as a direct cause of the pathological syndrome or involved in regulation of mechanisms of its formation. At that, activated forms of ultra-low doses of antibodies are raised against antigens of exogenous or endogenous origin, against autologous antigens, fetal antigens; anti-idiotypic antibodies are used too..
11/14/13
20130302312
Method of treating a pathological syndrome and a pharmaceutical agent
Pharmaceutical agent for treating a pathological syndrome contains activated form of ultra-low doses of monoclonal, polyclonal or natural antibodies to an antigen, wherein said activated form is prepared by means of repeated consecutive dilution and external treatment, predominantly based on homeopathic technology, and said antigen is a substance or a drug acting as a direct cause of the pathological syndrome or involved in regulation of mechanisms of its formation. At that, activated forms of ultra-low doses of antibodies are raised against antigens of exogenous or endogenous origin, against autologous antigens, fetal antigens; anti-idiotypic antibodies are used too..
11/14/13
20130302293
Compositions, cells, kits and methods for autologous stem cell therapy
Described herein are compositions, kits and methods for stimulating angiogenic functions of stem cells and/or progenitor cells having pro-angiogenic potential (e.g., endothelial progenitor cells (epcs), mesenchymal stem cells (mscs)) before transplantation (e.g., ex vivo cell therapy) based on the discovery that functional recovery of cd34+ cells from coronary artery disease (cad) patients is improved by transfection of antagomirs against one or more mirs of a plurality of mirs identified to be over-expressed in cells from cad patients. Described herein are methods to recover the functions of epcs isolated from patients with cardiovascular disease (e.g., cad or peripheral artery disease (pad)) by bioengineering the cells with antagomirs and/or premirs to specific micro-rnas.
11/14/13
20130300018
Polyhydroxyalkanoate medical textiles and fibers
Absorbable polyester fibers, braids, and surgical meshes with prolonged strength retention have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate.
11/14/13
20130299407
Systems and methods for preparing autologous fibrin glue
The invention provides a system for preparing an autologous solid-fibrin web suitable for regenerating tissue in a living organism. The system includes a sealed primary container containing a separation medium and a low-density high-viscosity liquid.
11/07/13
20130295061
Dosage unit formulations of autologous dermal fibroblasts
Dosage units consist of an autologous cell therapy product composed of fibroblasts grown for each individual to be treated. The suspension of autologous fibroblasts, grown from a biopsy of each individual's own skin using current good manufacturing practices (cgmp), and standard tissue culture procedures, is supplied in vials containing cryopreserved fibroblasts or precursors thereof, having a purity of at least 98% fibroblasts and a viability of at least 85%, for administration of from one to six ml, preferably two ml, of cells at a concentration of from 1.0-2.0×107 cells/ml.
10/31/13
20130287753
Compositions and methods for cartilage repair
Autologous compositions and methods are provided for cartilage repair in patients in need thereof. Some aspects include combinations of platelet-based materials with chondrogenesis inducing agents in the presence or absence of cell-based therapies..
10/17/13
20130274138
Gene signatures for prediction of therapy-related myelodysplasia and methods for identification of patients at risk for development of the same
In one embodiment, a gene expression signature for predicting risk of developing therapy-related myelodysplasia or acute myeloid leukemia (t-mds/aml) after autologous hematopoietic cell transplantation (ahct) is provided. In another embodiment, a method for predicting a risk for development of t-mds/aml after ahct is provided.
10/17/13
20130274114
Multipotent stem cell-based culture systems and models
This invention generally relates to multipotent stem cell-based research tools. More particularly, the present invention relates to culture systems and 3-dimensional tissue models that may be used for identifying agents useful for treating diseases and conditions and that are suitable for high throughput screening applications.
10/03/13
20130261676
Bone anchor
A biocompatible implantable bone anchor is provided that has a threaded first portion that engages and anchors into a bone. The implant also has a neck region extending from the first portion adapted to promote autologous cell growth thereon at an interface of the bone and one or more epidermal or gum layers, the neck region having a plurality of channels extending about the neck region.
10/03/13
20130259919
Surgical device for skin therapy or testing
A device, and method of making the device, capable of therapeutic treatment and/or for in vitro testing of human skin. The device may be used on skin wounds for burned, injured, or diseased skin, and provides structures and functions as in normal uninjured skin, such as barrier function, which is a definitive property of normal skin.
10/03/13
20130259845
Treatment of premature birth complications
The present invention provides methods of treating one or more complications of premature birth suffered by premature infants, comprising administering to the premature infant umbilical cord blood stem cells and, optionally, placental stem cells. The present invention also provides methods of combining and administering, and compositions comprising, umbilical cord blood stem cells, particularly autologous cord blood cells, and placental stem cells for the treatment of premature infants..
09/26/13
20130253553
Percutaneous methods and apparatus for creating native tissue venous valves
Percutaneous methods and apparatuses for forming a venous valve from autologous tissue. A catheter having a retractable dissecting system received therein is delivered to a target location where a new venous valve is to be created.
09/26/13
20130252278
Process of application procedures through cell biology for animal use
Process of application procedures through cell biology for animal use, the invention is applied to the field of cell biology, specifically the isolation, in vitro culture, cryopreservation, cell differentiation and application of mesenchymal stem cells derived from adipose tissue of animals for autologous cell therapy purposes. Strategically seeks to establish, from the adipose tissue collection, all events resulting in schematic form, in order to obtain a homogeneous extract of mesenchymal stem cells.
09/19/13
20130244244
Predicting allergic reactions
This present invention provides a method of predicting immunogenicity and hypersensitivity or allergic reactions to chemical compounds, therapeutics, cosmetics and other chemical compositions. The method uses an in vitroassay employing autologous bloodderived cells and an autologous cultured skin biopsy and is of particular utility in the identification and prediction of skin sensitizers that cause allergic contact dermatitis..
09/12/13
20130236437
Compositions, kits and methods for treatment of cardiovascular, immunological and inflammatory diseases
Compositions, kits, cells and methods for treating cardiovascular (e.g., myocardial ischemia and heart failure), immunological, and inflammatory diseases or disorders involve the use of the mature and precursor sequences of micrornas 142-5p, 142-3p, 17-5p, 17-3p, 374, and 20a, and of antisense molecules complementary to these sequences, to manipulate processes relevant to, for example, the cardiac response to stress, including survival signaling, angiogenesis, stem cell differentiation along muscle or vascular lineages, and repression or promotion of cardiac myocyte growth. Also described are methods to treat cardiovascular, immunological and inflammatory diseases by engineering cells containing specific micro-rnas or antagomirs against specific mrnas.
08/29/13
20130224160
Treatment of vocal cords with autologous dermal fibroblast formulation
Dosage units consist of an autologous cell therapy product composed of fibroblasts grown for each individual to be treated for augmentation or regeneration of vocal cords. The suspension of autologous fibroblasts, grown from a biopsy of each individual's own buccal mucosa or skin using current good manufacturing practices (cgmp) and standard tissue culture procedures, is supplied in vials containing cryopreserved fibroblasts or precursors thereof, having a purity of at least 98% fibroblasts and a viability of at least 85%, for administration of from one to six ml, preferably two ml administered three times approximately three to six weeks apart, of cells at a concentration of from 1.0-2.0×107 cells/ml..
08/22/13
20130216601
Three-dimensional bone implant and method for producing same
A method for ex vivo production of a three-dimensional bone implant adapted for implantation to a patient, implants produced by such a method, and uses of such implants. The method comprises disposing differentiated osteoblasts on a matrix support comprising at least one of collagen, calcium phosphate, calcium sulfate and tricalcium phosphate; contacting the differentiated osteoblasts on the matrix with autologous blood serum from the patient, comprising at least one of a growth factor and a cytokine; and disposing the differentiated osteoblasts on the matrix support and the medium in a bioreactor, in which production of the bone implant is performed..
08/01/13
20130197470
Adaptable perioperative cell-salvage system and methods and disposable units for same
A blood-collection system configured to permit selection of either collection and disposal of shed blood from a patient or collection and processing of shed blood for autologous transfusion back to the patient includes an automated blood-processing machine. The system may also include a blood-collection reservoir, a separation chamber, and a fluid conduit.


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Autologous topics: Autologous, Stem Cells, Differentiation, Fibroblast, Cell Therapy, Transplant, Cell Differentiation, Tissue Engineering, Myeloid Leukemia, Gene Expression, Acute Myeloid Leukemia, Complication, Umbilical Cord, Premature Birth, Premature Infant

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This listing is a sample listing of patent applications related to Autologous for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Autologous with additional patents listed. Browse our RSS directory or Search for other possible listings.
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