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Autoimmune Disorder

Autoimmune Disorder-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Compositions and methods of use of phorbol esters
Biosuccess Biotech Co. Ltd.
November 09, 2017 - N°20170319533

Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of chronic and acute conditions. Such conditions may be caused by disease, be symptoms or sequelae of disease. Chronic and acute conditions may be due to viral infections such as hiv and aids, neoplastic diseases stroke, kidney disease, urinary incontinence, autoimmune ...
Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions
Biosuccess Biotech Co. Ltd.
November 02, 2017 - N°20170316169

A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune ...
Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions
Biosuccess Biotech Co. Ltd.
November 02, 2017 - N°20170316168

A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune ...
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Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions
Biosuccess Biotech Co. Ltd.
November 02, 2017 - N°20170316166

A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune ...
Methods of treating graft versus host disease using il-2 muteins
Biosuccess Biotech Co. Ltd.
November 02, 2017 - N°20170313753

Described herein are immunosuppressive molecules including immunosuppressive variants of il-2, and use of such molecules to treat inflammatory and autoimmune disorders.
Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions
Ubiome, Inc.
October 26, 2017 - N°20170308660

A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune ...
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Autoimmune Disorder Patent Applications
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Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions
Ubiome, Inc.
October 26, 2017 - N°20170308658

A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune ...
Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions
Ubiome, Inc.
October 26, 2017 - N°20170308657

A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune ...
Use of levocetirizine and montelukast in the treatment of autoimmune disorders
Ubiome, Inc.
October 19, 2017 - N°20170296534

The embodiments described herein include methods and formulations for treating autoimmune disorders. The methods and formulations include, but are not limited to, methods and formulations for delivering effective concentrations of levocetirizine and montelukast to a patient in need. The methods and formulations can comprise conventional and/or modified-release elements, providing for drug delivery to the patient.
Polypeptides and uses thereof as a drug for treatment of autoimmune disorders
Compugen Ltd.
September 28, 2017 - N°20170275344

This invention, in at least some embodiments, relates to a protein c1orf32 and its variants and fragments and fusion proteins thereof, and methods of use thereof for immunotherapy, and drug development, including but not limited to as immune modulators and for immune therapy, including for autoimmune disorders.
Modulators of retinoid-related orphan receptor gamma
Orphagen Pharmaceuticals, Inc.
September 21, 2017 - N°20170267712

Methods for modulating (inhibiting or stimulating) retinoid-related orphan receptor γ (rorγ) activity. This modulation has numerous effects, including inhibition of th-17 cell function and/or th-17 cell activity, and inhibition of re-stimulation of th-17 cells, which are beneficial to treatment of inflammation and autoimmune disorders. Stimulation of rorγ results in stimulation of th-17 cell function ...
Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors
Incyte Holdings Corporation
September 07, 2017 - N°20170253598

The present invention provides azetidinyl phenyl, pyridyl, or pyrazinyl carboxamide derivatives, as well as their compositions and methods of use, that modulate the activity of janus kinase (jaks) and are useful in the treatment of diseases related to the activity of jak including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
Liquid formulation comprising gm-csf neutralizing compound
Takeda Gmbh
September 07, 2017 - N°20170252436

The present invention relates to aqueous formulations comprising a compound neutralizing gm-csf in concentrations of at least 20 mg/ml, a tonicity modifier, a buffer and one or more of surfactants, amino acids, antioxidants and/or chelators, wherein the composition is stable. The ingredients of the formulation preferably provide stability to the compound neutralizing gm-csf in view of long-term storage. In ...
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Eluting matrix and uses thereof
The General Hospital Corporation
August 31, 2017 - N°20170246250

Cxcl12 polypeptide eluting matrices encapsulating at least one cell are described for use in the treatment of autoimmune disorders.
Piperidin-4-yl azetidine derivatives as jak1 inhibitors
Incyte Holdings Corporation
August 31, 2017 - N°20170246157

The present invention provides piperidin-4-yl azetidine derivatives, as well as their compositions and methods of use, that modulate the activity of janus kinase 1 (jak1) and are useful in the treatment of diseases related to the activity of jak1 including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
Universal chimeric antigen expressing immune cells for targeting of diverse multiple antigens and method of ...
Gemoab Monoclonals Gmbh
August 24, 2017 - N°20170240612

The present invention relates to immune cell-based anti-cancer therapeutics and methods of using the therapeutics in the treatment of cancer.
Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response
Idera Pharmaceuticals, Inc.
August 17, 2017 - N°20170233741

The invention provides novel immune regulatory oligonucleotides (iro) as antagonist of tlrs and methods of use thereof. These iros have unique sequences that inhibit or suppress tlr-mediated signaling in response to a tlr ligand or tlr agonist. The methods may have use in the prevention and treatment of cancer, an autoimmune disorder, airway inflammation, inflammatory disorders, infectious disease, skin disorders, ...
Polypeptides and uses thereof as a drug for treatment of multiple sclerosis, rheumatoid arthritis and ...
Compugen Ltd.
August 17, 2017 - N°20170232062

This invention relates to a protein c1orf32 and its variants and fragments and fusion proteins thereof, and methods of use thereof for immunotherapy, and drug development, including but not limited to as immune modulators and for immune therapy, including for autoimmune disorders.
Pharmaceutical composition containing dimethyl fumarate for administration at a low daily dose
Forward Pharma A/s
August 17, 2017 - N°20170231943

The present invention relates to pharmaceutical compositions containing dimethyl fumarate (dmf), more specifically, the present invention relates to a pharmaceutical composition for oral use in treating hyperproliferative, inflammatory or autoimmune disorders by administering a low daily dosage in the range of 410 mg±5% or 400 mg±5% dimethyl fumarate, wherein the pharmaceutical formulation is in the form of an erosion matrix ...
Controlled release pharmaceutical compositions comprising a fumaric acid ester
Forward Pharma A/s
August 17, 2017 - N°20170231941

The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are suitable for use in the treatment of e. G. Psoriasis or other hyperproliferative, inflammatory or autoimmune disorders and are designated to release the fumaric acid ester in a controlled manner so that local high concentrations of the active substance ...
N-terminally truncated interleukin-38
Fraunhofer-gesellschaft Zur FÖrdeung Angewandten Forschung E.v.
August 03, 2017 - N°20170218039

The present invention pertains to an n-terminally truncated interleukin (il)-38 protein, or functional variants thereof, as well as to nucleic acids and vectors encoding the truncated il-38 peptide and recombinant cells comprising these nucleic acids or vectors. The invention shows that il-38 is n-terminally processed and that the truncated version of the cytokine acts as an antagonist of immune ...
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