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Autoimmune Diseases

Autoimmune Diseases-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Antibodies specific for mmp9
Merck Patent Gmbh
August 17, 2017 - N°20170233495

The present invention relates to new proteins that bind to mmp9 and comprise at least one fragment of a heavy chain variable region and/or at least one fragment of a light chain variable region of an antibody. In particular, the mmp9 binding proteins according to the invention are able to neutralize mmp9 activity and are useful in the prevention ...
Anti-cd40 antibodies and uses thereof
Biogen Ma Inc.
August 17, 2017 - N°20170233485

Antibodies and antibody fragments that bind to human cd40 and inhibit interaction between cd40 and its ligand, cd40l are disclosed. Also disclosed are methods of using the antibodies and antibody fragments to inhibit hyperactivation of b or t cells and treat or prevent disorders such as autoimmune diseases.
Antibody therapeutics that bind ctla4
Sorrento Therapeutics, Inc.
August 17, 2017 - N°20170233476

There is disclosed compositions and methods relating to or derived from anti-ctla4 antibodies. More specifically, there is disclosed fully human antibodies that bind ctla4, ctla4-antibody binding fragments and derivatives of such antibodies, and ctla4-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, ...
Autoimmune Diseases Patent Pack
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Autoimmune Diseases Patent Applications
Download 177+ Autoimmune Diseases-related PDFs
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  • 177+ full patent PDF documents of Autoimmune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Flt3 receptor antagonists
UniversitÉ De Strasbourg
August 17, 2017 - N°20170233354

The invention pertains to novel flt3 receptor antagonists of general formula (1). The compounds are useful for the treatment or the prevention of pain disorders, cancer and autoimmune diseases.
Soluble mediator
The Walter And Eliza Hall Institute Of Medical Research
August 17, 2017 - N°20170232061

The present disclosure relates to a soluble cd52 glycoprotein and its use in treating diseases regulated by effector t-cells, for example autoimmune diseases such as type 1 diabetes. The present disclosure also relates to fusion proteins comprising the soluble glycoprotein, to cells expressing high levels of cd52, and to diagnostic methods based on the detection of cd52 expression levels in a ...
Aza-heteroaryl compounds as pi3k-gamma inhibitors
The Walter And Eliza Hall Institute Of Medical Research
August 17, 2017 - N°20170232016

And pharmaceutically acceptable salts thereof, wherein x, y, z, a, w, r4, r5, and r6 are defined herein, that inhibit the activity of phosphoinositide 3-kinases-gamma (pi3kγ) and are useful in the treatment of diseases related to the activity of pi3kγ including, for example, autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.
Autoimmune Diseases Patent Pack
Download 177+ patent application PDFs
Autoimmune Diseases Patent Applications
Download 177+ Autoimmune Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Autoimmune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Aptamers for use against autoantibody-associated diseases
Berlin Cures Holding Ag
August 10, 2017 - N°20170226513

The present invention relates to new aptamer molecules for use in the treatment and/or diagnosis of autoimmune diseases associated with autoantibodies against g-protein coupled receptors, a pharmaceutical composition comprising such aptamer molecules, an apheresis column comprising such aptamer molecules and a method for the determination of nucleotide sequences for use as sequences of aptamer molecules.
Antibody therapeutics that bind cd137
Sorrento Therapeutics, Inc.
August 10, 2017 - N°20170226215

There is disclosed compositions and methods relating to or derived from anti-cd137 antibodies. More specifically, there is disclosed fully human antibodies that bind cd137, cd137-antibody binding fragments and derivatives of such antibodies, and cd137-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, ...
An anti-cd45rc antibody for use as drug
UniversitÉ De Nantes
August 10, 2017 - N°20170226209

The invention relates to an isolated anti-cd45rc antibody for use in preventing or treating transplant rejection, autoimmune diseases, unwanted immune responses against proteins expressed in the course of gene therapy and/or therapeutic proteins, allergy as well as lymphoma or cancer which are associated with cd45rc+ cells. The invention relates to an isolated anti-cd45rc antibody for use ...
Modified peptides and their use for treating autoimmune diseases
Immupharma France Sa
August 10, 2017 - N°20170226167

The present invention relates to a peptide, or a salt thereof, comprising or consisting of the amino acid sequence ihmvyskrsgkprgyafiey, comprising one or more post-translational modifications.
Crystalline forms of a bruton's tyrosine kinase inhibitor
Pharmacyclics Llc
August 10, 2017 - N°20170226112

Described herein is the bruton's tyrosine kinase (btk) inhibitor 1-((r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the btk inhibitor, as well as methods of using the btk inhibitor, alone or in combination with other ...
Methods of treating inflammatory and autoimmune diseases and disorders
Yale University
August 10, 2017 - N°20170224617

Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid ...
Her2/neu-specific antibodies and methods of using same
Macrogenics, Inc.
August 03, 2017 - N°20170218083

This invention relates to antibodies that specifically bind her2/neu, and particularly chimeric 4d5 antibodies to her2/neu, which have reduced glycosylation as compared to known 4d5 antibodies. The invention also relates to methods of using the 4d5 antibodies and compositions comprising them in the diagnosis, prognosis and therapy of diseases such as cancer, autoimmune diseases, inflammatory disorders, and infectious ...
Autoimmune Diseases Patent Pack
Download 177+ patent application PDFs
Autoimmune Diseases Patent Applications
Download 177+ Autoimmune Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Autoimmune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
School Corporation, Azabu Veterinary Medicine Educational Institution
August 03, 2017 - N°20170216378

Species of human-derived bacteria belonging to the clostridia class have been shown to induce accumulation of regulatory t cells (treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
Automated immunoanalyzer system for performing diagnostic assays for allergies and autoimmune diseases
Hycor Biomedical, Llc
July 27, 2017 - N°20170212111

A quantitative method for performing an automated diagnostic assay, comprising: incubating a capture reagent with a streptavidin-coated medium to form a solid phase complex; washing the solid phase complex to remove excess capture reagent; incubating the solid phase complex with a serum sample to form an immune complex; washing the immune complex to remove any unbound sample; incubating the immune ...
Use of pdl1 expressing cells to convert t cells into regulatory t cells
The United States Of America, As Represented By The Secretary, Department Of Health And Human
July 27, 2017 - N°20170211042

The present invention provides methods and compositions for converting a t cell into a cell that exhibits at least one regulatory t cell phenotype. The converted t cell is generated by contacting a t cell with a cell that is modified to comprise an agent capable of activating pd1 signaling in a t cell. The converted t cell is useful ...
Antibody binding to fcrn for treating autoimmune diseases
Hanall Biopharma Co., Ltd.
July 27, 2017 - N°20170210805

The present disclosure relates to an isolated anti-fcrn antibody, which is an antibody binding to fcrn (stands for neonatal fc receptor, also called fcrp, fcrb or brambell receptor) that is a receptor with a high affinity for igg or a fragment thereof, a method of preparing thereof, a composition for treating autoimmune disease, which comprises the antibody, and a method ...
Antibody binding to fcrn for treating autoimmune diseases
Hanall Biopharma Co., Ltd.
July 27, 2017 - N°20170210801

The present disclosure relates to an isolated anti-fcrn antibody, which is an antibody binding to fcrn (stands for neonatal fc receptor, also called fcrp, fcrb or brambell receptor) that is a receptor with a high affinity for igg or a fragment thereof, a method of preparing thereof, a composition for treating autoimmune disease, which comprises the antibody, and a method ...
Composition containing smad protein for treatment of autoimmune diseases, a fusion protein comprising smad protein, ...
Hanall Biopharma Co., Ltd.
July 27, 2017 - N°20170210783

The present invention relates to a composition and a fusion protein for prevention or treatment of autoimmune diseases, which contain a smad protein, and provides a method for prevention or treatment of autoimmune diseases, including lupus nephritis and rheumatoid arthritis.
Pegylated interferon-beta variant
Abion Inc.
July 27, 2017 - N°20170209588

The present invention provides a pegylated ifn-β variant and a composition for preventing or treating hyperproliferative diseases, inflammatory diseases, autoimmune diseases or viral infectious diseases, the composition comprising the pegylated ifn-β variant as an effective ingredient. The pegylated ifn-β variant of the present invention has an excellent anti-viral efficacy, immune regulatory function and anti-cell ...
Method for preparing dendritic cells with increased specific gene expression, and composition for treating or ...
Jw Creagene Inc.
July 27, 2017 - N°20170209557

The present invention relates to a method for generating semi-mature dendritic cells by treating immature dendritic cells with the auto-antigen, cytokine, and pge2 as a target for the treatment of autoimmune diseases, particularly rheumatoid arthritis, in which the levels of nr4a2 and/or ubash3b at gene or protein are increased more than 2-fold compared to the immature dendritic ...
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