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Autoimmune Diseases

Autoimmune Diseases-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Self assembling nucleic acid nanostructures
Exicure, Inc.
June 22, 2017 - N°20170175121

Stable self-assembling nucleic acid nanostructures comprising: —a plurality of oligonucleotides, —a plurality of g-quadruplex forming nucleic acids linked to the plurality of oligonucleotides, and —a plurality of g-quadruplex stabilizing domains linked to the g-quadruplex forming nucleic acids. The nucleic acid nanostructures are suitable for use as agonists or antagonists of nucleic acid interacting complexes, such as toll-like ...
NEW Bi-terminal pegylated integrin-binding peptides and methods of use thereof
The Regents Of The University Of California
June 22, 2017 - N°20170174723

The present invention provides bi-terminal pegylated peptide conjugates that target an integrin such as αvβ6 integrin. In particular embodiments, the peptide conjugates of the present invention further comprise a biological agent such as an imaging agent or a therapeutic agent, e. G., covalently attached to one of the peg moieties. The peptide conjugates of the present ...
NEW Inhibitors of cyclin-dependent kinase 7 (cdk7)
Syros Pharmaceuticals, Inc.
June 22, 2017 - N°20170174692

The present invention provides novel compounds described herein, such as of formula (i), and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases (e. G., cancers (e. G., leukemia, melanoma, multiple myeloma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, ...
NEW Autoimmune Diseases Patent Pack
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Autoimmune Diseases Patent Applications
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  • 177+ full patent PDF documents of Autoimmune Diseases-related inventions.
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NEW Pharmaceutical composition comprising bee venom-phospholipase a2 (bv-pla2) for treating or preventing diseases related to degradation ...
University-industry Cooperation Group Of Kyung Hee University
June 22, 2017 - N°20170173120

The present invention relates to a pharmaceutical composition for treating or preventing a disease related to abnormal suppression of regulatory t cell activity comprising a polypeptide comprising a bee venom-pla2 amino acid sequence exclusive of a leader sequence as an active ingredient. The secretory bee venom-phospholipase a2 of the present invention activates a regulatory t cell and suppress a differentiation ...
NEW Har-nds-derived stem cells, method for separating same, and use thereof
Eutilex Co., Ltd
June 22, 2017 - N°20170173077

The present invention relates to hyaluronic acid-rich node and duct system (har-nds)-derived stem cells, a method for separating the same, and a use thereof and, more specifically, to node and ductal stem cells (ndscs), which are adult stem cells having an ability to differentiate into har-nds-derived neural cells, and hematopoietic stem cells having an ability to differentiate into blood ...
NEW Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same
Platform Brightworks Two, Ltd.
June 22, 2017 - N°20170172971

There may be provided compositions of lipophilic pharmaceutical agents with improved solubility and stability. For example, there may be provided a non-aqueous composition that comprises a lipophilic pharmaceutical agent, and an amphiphilic polymeric solvent such as peg400 but essentially free of organic solvents and non-solubilized particles. The composition may be further diluted with a desired aqueous diluent such as an ...
Autoimmune Diseases Patent Pack
Download 177+ patent application PDFs
Autoimmune Diseases Patent Applications
Download 177+ Autoimmune Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Autoimmune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
O-glcnac transferase (ogt) inhibitors and uses thereof
The United States Of America, As Represented By The Secretary, Department Of Health And Human
June 15, 2017 - N°20170166558

The present invention provides inhibitors of o-glcnac transferase. Typically, the inhibitors are quinolinone-6-sulfonamides. The invention also provides pharmaceutical compositions thereof and methods for using the same in diabetes and complications thereof, metabolic diseases, neurodegenerative diseases, proliferative diseases (e. G., cancers), autoimmune diseases, and inflammatory diseases.
Methods to treat diseases with protein, peptide, antigen modification and hemopurification
The United States Of America, As Represented By The Secretary, Department Of Health And Human
June 15, 2017 - N°20170165334

The current invention discloses methods to modify protein and peptide and antigen to treat disease such as pathogen infection, autoimmune diseases and cancer. The method involves increasing the molecular weight of the protein by connecting multiple peptide units with site specific conjugation to extend the in vivo half life. The current invention also discloses methods to construct activatable enzyme, which ...
Pharmaceutical composition comprising bee venom-phospholipase a2 (bv-pla2) for treating or preventing diseases related to degradation ...
University-industry Cooperation Group Of Kyung Hee University
June 15, 2017 - N°20170165328

The present invention relates to a pharmaceutical composition for treating or preventing a disease related to abnormal suppression of regulatory t cell activity comprising a polypeptide comprising a bee venom-pla2 amino acid sequence exclusive of a leader sequence as an active ingredient. The secretory bee venom-phospholipase a2 of the present invention activates a regulatory t cell and suppress a differentiation ...
Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[...
Arena Pharmaceuticals, Inc.
June 08, 2017 - N°20170159088

The present invention relates to processes and intermediates useful in the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid of formula (ia) and salts thereof, an s1p1 receptor modulator that is useful in the treatment of s1p1 receptor-associated disorders, for example, diseases and disorders mediated by lymphocytes, transplant rejection, ...
Immunoglobulin variants and uses thereof
Genentech, Inc.
June 08, 2017 - N°20170158773

The invention provides humanized and chimeric anti-cd20 antibodies for treatment of cd20 positive malignancies and autoimmune diseases.
Ip-10 antibodies and their uses
Bristol-myers Squibb Company
June 08, 2017 - N°20170158757

The present invention provides isolated monoclonal antibodies, particularly human antibodies, that bind to ip-10 with high affinity, inhibit the binding of ip-10 to its receptor, inhibit ip-10-induced calcium flux and inhibit ip-10-induced cell migration. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also ...
Novel compounds
Bristol-myers Squibb Company
June 08, 2017 - N°20170158724

And pharmaceutically acceptable salts and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases in which modulation of sting (stimulator of interferon genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases, cancer, pre-cancerous ...
Autoimmune Diseases Patent Pack
Download 177+ patent application PDFs
Autoimmune Diseases Patent Applications
Download 177+ Autoimmune Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Autoimmune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
The Walter And Eliza Hall Institute Of Medical Research
June 08, 2017 - N°20170158666

Disclosed are compounds which inhibit the activity of anti-apoptotic bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic bcl-2 protein.
Composition using metformin for preventing or treating immune diseases including lupus
Catholic University Industry Academic Cooperation Foundation
June 08, 2017 - N°20170157069

The present invention relates to a composition for preventing or treating immune diseases through the suppression of b cell activity induced by metformin. More particularly, the present invention relates to a composition comprising a metformin compound or a pharmaceutically acceptable salt thereof as an active ingredient for preventing or treating immune diseases, wherein the composition is characterized by suppression or ...
Anti-cd19 antibodies
Immunomedics, Inc.
June 01, 2017 - N°20170152315

The present invention provides humanized, chimeric and human anti-cd19 antibodies, anti-cd19 antibody fusion proteins, and fragments thereof that bind to a human b cell marker. Such antibodies, fusion proteins and fragments thereof are useful for the treatment and diagnosis of various b-cell disorders, including b-cell malignancies and autoimmune diseases. In more particular embodiments, the humanized anti-cd19 antibodies may comprise one ...
Aminopyridazinone compounds as protein kinase inhibitors
Eternity Bioscience Inc.
June 01, 2017 - N°20170152264

The present disclosure provides a compound of formula (i) and the use thereof for the therapeutic treatment of human cancers including b-cell lymphoma and autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis.
Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo
Applied Molecular Transport Llc
June 01, 2017 - N°20170151307

The present disclosure relates to pharmaceutical compositions comprising a non-naturally occurring fusion molecule and one or more pharmaceutically acceptable carriers, formulated for oral delivery to a subject, and designed to provide for improved, effective therapies for treatment of, e. G., inflammatory diseases, autoimmune diseases, cancer, metabolic disorders, and growth deficiency disorders.
Use of leukotriene b4 in combination with a toll-like receptor ligand, a rig-i-like receptor ligand, ...
Universite De Laval
June 01, 2017 - N°20170151204

The present invention relates to the use of leukotriene b4 to enhance the response of toll-like receptor (tlr), rig-i-like receptor (rlr), and nod-like receptor (nlr) when stimulated simultaneously with respective proper ligands. The use in combination of ltb4 with those ligands is useful to potentiate immune response for the treatment of autoimmune diseases, immunosuppressive diseases, as well as immunological disorders.
Use of mcoln-1 modulators to regulate cell migration
Universite De Laval
May 25, 2017 - N°20170145423

The present invention relates to the use of modulators of mcoln-1 for modulating the cells migration, in particular the migration of dendritic cells and tumor cells, especially for antitumoral vaccination, autoimmune diseases treatment, and metastasis prevention.
Inhibitor of bruton's tyrosine kinase
Universite De Laval
May 25, 2017 - N°20170144986

Provided are a compound represented by formula (iii) or pharmaceutically acceptable salts, solvates, active metabolites, polymorphs, esters, tautomers or prodrugs thereof, pharmaceutical compositions containing the compound represented by formula (iii), and the application of the pharmaceutical compositions as selective inreversible inhibitor of bruton's tyrosine kinase for the prevention and treatment of inflammation, autoimmune diseases (such as rheumatoid arthritis) associated with ...
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