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Autoimmune Disease

Autoimmune Disease-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Nanoparticle conjugates and uses thereof
Massachusetts Institute Of Technology
May 17, 2018 - N°20180133343

The targeted delivery of therapeutic agents to specific cells remains a challenge in drug delivery. Provided herein are nanoparticle-targeting agent conjugates that can be used for the targeted delivery of therapeutic agents to certain cells and target tissues. The conjugates comprise nanoparticles (e. G., metal nanoparticles such as gold nanoparticles) with organic outer shells capable of adsorbing large numbers of ...
NEW Compositions comprising bacterial strains
4d Pharma Research Limited
May 17, 2018 - N°20180133265

The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
NEW Therapeutic ozone agent and treatment
May 17, 2018 - N°20180133248

The use of a medical therapeutic ozone agent in vivo to treat a variety of disorders including, but not limited to hypoxic conditions, autoimmune disease, fibrotic disease, inflammatory disease, neurodegenerative disease, infectious disease, lung disease, heart and vascular disease, metabolic disease, and cancer, wherein the therapeutic ozone agent is administered in a therapeutically effective amount, which can convert carbon monoxide ...
Autoimmune Disease Patent Pack
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Autoimmune Disease Patent Applications
Download 255+ Autoimmune Disease-related PDFs
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inventor
  • 255+ full patent PDF documents of Autoimmune Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Use of aptamers in therapy and/or diagnosis of autoimmune diseases
Max-delbrueck-centrum Fuer Molekulare Medizin
May 10, 2018 - N°20180127757

The present invention is directed to an aptamer comprising or consisting of the nucleic acid sequence of seq id no. 1, seq id no. 2, seq id no. 3 and/or a nucleic acid sequence being at least 80% identical to one of seq id no. 1, 2 and 3 for use in therapy and/or diagnosis of autoimmune diseases, wherein the autoimmune disease is cardiomyopathy, dilated ...
Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3)
Anaptysbio, Inc.
May 10, 2018 - N°20180127500

The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the t cell immunoglobulin and mucin protein-3 (hm-3). The invention provides a tim-3-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and ...
Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
May 10, 2018 - N°20180127425

Wherein r1a, r1b, r2, r4, r5, r6, r7, r8, w, x, y, z, cy, and the subscript a are as defined herein. The present invention relates to compounds inhibiting autotaxin (npp2 or enpp2), methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving ...
Autoimmune Disease Patent Pack
Download 255+ patent application PDFs
Autoimmune Disease Patent Applications
Download 255+ Autoimmune Disease-related PDFs
For professional research & prior art discovery
inventor
  • 255+ full patent PDF documents of Autoimmune Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Substituted benzimidazoles and benzopyrazoles as ccr(4) antagonists
Chemocentryx, Inc.
May 10, 2018 - N°20180127395

Benzimidazole, benzopyrazole and benzotriazole compounds are provided which bind to ccr(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft rejection and cancer.
Il-2 variants for the treatment of autoimmune diseases
Delinia, Inc.
May 10, 2018 - N°20180125941

This disclosure provides for a method for treating a condition by administering to a subject in need thereof a therapeutically-effective amount of a compound that comprises an il-2 receptor-binding moiety. The methods described in the present disclosure provide enhanced pharmacokinetic profiles. The disclosure also provides methods for treating autoimmune disease comprising administering a therapeutically-effective amount of a fusion protein comprising ...
Probiotic compositions for improving metabolism and immunity
New York University
May 10, 2018 - N°20180125900

The application relates to methods based on modulating mammalian intestinal microbiota and related probiotic and prebiotic compositions. Specifically, the application relates to the use of novel bacterial genera ileibacterium and dubosiella, including their species i. Valens (i. Valens) and dubosiella newyorkensis (d. Newy), respectively, and closely related otus within the family erysipelotrichaceae that resemble either ileibacterium spp. Or dubosiella spp. ...
T-reg cell expansion
The Board Of Trustees Of The University Of Illinois
May 03, 2018 - N°20180119100

This invention relates to methods of expanding t regulatory cells through ox40l and jagged-1 induced signaling. The methods can be used for treating autoimmune diseases.
Compositions and methods for diagnosing and treating autoimmune diseases
The Regents Of The University Of Colorado, A Body Corporate
May 03, 2018 - N°20180118801

Disclosed are compositions and methods for detecting, isolating, and/or characterizing a t cell or autoantibody associated with type i diabetes. The composition and methods comprise the use of a hybrid insulin peptide having an n-terminal amino acid sequence taken from the human insulin peptide and a c-terminal amino acid sequence taken from a secretory granule protein that are joined ...
Imidazo isoindole derivative, preparation method therefor and medical use thereof
Shanghai Hengrui Pharmaceutical Co., Ltd.
May 03, 2018 - N°20180118750

The present invention relates to an imidazo isoindole derivative, a preparation method therefor and a medical use thereof. In particular, the present invention relates to the imidazo isoindole derivative as shown in the formula (i), a preparation method and pharmaceutical composition containing the derivative, and a use thereof for treating diseases with a pathological characteristic of the ido-mediated tryptophan metabolic ...
Inhibitors of leukotriene a4 hydrolase
Celtaxsys, Inc.
May 03, 2018 - N°20180118735

The present invention is directed to compounds encompassed by the formula (i), pharmaceutical compositions thereof, methods for inhibiting lta-4 hydrolase, and methods for the treatment of a disease and disorder which is ameliorated by the inhibition of lta4-h activity. Non-limiting examples of such diseases and conditions include inflammatory and autoimmune diseases and disorders.
Autoimmune Disease Patent Pack
Download 255+ patent application PDFs
Autoimmune Disease Patent Applications
Download 255+ Autoimmune Disease-related PDFs
For professional research & prior art discovery
inventor
  • 255+ full patent PDF documents of Autoimmune Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Small molecule compounds targeting pbx1 transcriptional complex
The Johns Hopkins University
May 03, 2018 - N°20180118688

In accordance with one or more embodiments, the present invention provides a compound of formulas i, ii, and iii, for use in methods of inhibition of pbx1-dna interaction in a mammalian cell or population of cells, and for use in the treatment of medical conditions including but not limited to cancers, developmental disorders, inflammatory disorders, autoimmune diseases, or neuro-degenerative ...
Novel compound having immune disease treatment effect and use thereof
The Catholic University Of Korea Industry-academic Cooperation Foundation
May 03, 2018 - N°20180118668

The present invention relates to a novel compound capable of effectively preventing and treating immune diseases and a use thereof. The novel compound of the present invention has effects of inhibiting the production of inflammatory cytokines, increasing the activity of regulatory t cells having immunoregulatory functions, inhibiting the production of auto-antibodies to regulate excessive immune responses, and inhibiting the differentiation ...
Substituted hydroxystilbenes and their therapeutic applications
Resolvex Pharmaceuticals Inc.
May 03, 2018 - N°20180118667

It discloses a compound of formula i that inhibits the activities of numerous of protein kinases involving the signaling of inflammatory cytokines, therefore, the compound can be used for treating cancers, autoimmune diseases and inflammatory diseases.
Covalent conjugates of bet inhibitors and alpha amino acid esters
Glaxosmithkline Intellectual Property Development Limited
May 03, 2018 - N°20180117165

The present invention relates to covalent conjugates of bet inhibitors and alpha amino acid esters, processes for their preparation, compositions containing them, and to their use in the treatment of various disorders in particular inflammatory and autoimmune diseases, such as rheumatoid arthritis; and cancers.
Insulin mimotopes and methods of using the same
National Jewish Health
May 03, 2018 - N°20180117124

Methods for inhibiting an autoimmune disease by administering to a subject a therapeutically effective amount of a composition that induces conversion of naive t cells into foxp3+ regulatory t cells to induce immunosuppression in the subject. Methods for detecting in a subject an autoimmune disease or a predisposition to an autoimmune disease, and methods for assessing the efficacy of a ...
Methods of preventing and treating autoimmunity
The University Of Florida Research Foundation Incorporated
May 03, 2018 - N°20180116988

Methods of preventing, treating or ameliorating autoimmune diabetes by modulating the binding of mhc class ii molecules to antigenic peptides or fragments of antigenic peptides of the autoimmune disease by the administration of methyldopa. Pharmaceutical compositions containing therapeutically effective amounts of methyldopa in extended release formulations and methods of using the same are also provided.
Methods of monitoring conditions by sequence analysis
Adaptive Biotechnologies Corp.
April 26, 2018 - N°20180112278

There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer. Provided herein are methods for using dna sequencing to identify personalized biomarkers in patients with autoimmune disease and other conditions. Identified biomarkers can be used to determine the disease state for a subject with an autoimmune disease or ...
Tricyclic heterocyclic compounds useful as inhibitors of tnf
Bristol-myers Squibb Company
April 26, 2018 - N°20180111937

Disclosed are compounds of formula (i) or a salt thereof, wherein: x is n; w is: —(cr3r3)2-5-, —(cr3r3)x-y—(cr3r3)y-, —y—(cr3r3)2-3-y—, —cr3r3-y—(cr3r3)2-y—, —y—(cr3r3)2-y—cr3r3-; and y, r1, r2, ...
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