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Autoimmune Disease

Autoimmune Disease-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Canine autoimmune conditions and diagnosis and treatment thereof
The Translational Genomics Research Institute
June 15, 2017 - N°20170166964

The disclosure includes methods of identifying a dog at risk of developing a an autoimmune disease or condition, for example a hypothyroid disease or condition, comprising testing whether the dog exhibits one or more selected single nucleotide polymorphisms (snps), together with diagnostic kits for carrying out such methods, methods of treatment or prophylaxis of such autoimmune disease or condition, e. ...
Humanized antibodies against cd269 (bcma
Max-delbruck-centrum Fur Molekulare Medizin In Der Helmholtz-gemeinschaft
June 15, 2017 - N°20170166649

The invention relates to humanized antibodies or antibody fragments that bind cd269 (bcma), thereby disrupting the interaction between cd269 and its native ligands (baff and april), and their use in the treatment of plasma cell-mediated diseases such as multiple myeloma and autoimmune diseases.
O-glcnac transferase (ogt) inhibitors and uses thereof
The United States Of America, As Represented By The Secretary, Department Of Health And Human
June 15, 2017 - N°20170166558

The present invention provides inhibitors of o-glcnac transferase. Typically, the inhibitors are quinolinone-6-sulfonamides. The invention also provides pharmaceutical compositions thereof and methods for using the same in diabetes and complications thereof, metabolic diseases, neurodegenerative diseases, proliferative diseases (e. G., cancers), autoimmune diseases, and inflammatory diseases.
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Autoimmune Disease Patent Applications
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  • 255+ full patent PDF documents of Autoimmune Disease-related inventions.
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Pharmaceutical composition comprising bee venom-phospholipase a2 (bv-pla2) for treating or preventing diseases related to degradation ...
University-industry Cooperation Group Of Kyung Hee University
June 15, 2017 - N°20170165328

The present invention relates to a pharmaceutical composition for treating or preventing a disease related to abnormal suppression of regulatory t cell activity comprising a polypeptide comprising a bee venom-pla2 amino acid sequence exclusive of a leader sequence as an active ingredient. The secretory bee venom-phospholipase a2 of the present invention activates a regulatory t cell and suppress a differentiation ...
Agent for the treatment and or prophylaxis of an autoimmune disease and for the formation ...
Aicuris Gmbh & Co. Kg
June 15, 2017 - N°20170165326

The present invention relates to an agent for the treatment and/or prophylaxis of an autoimmune disease, an agent for the formation of regulatory t cells (treg) in an organism and various methods in which the agents according to the invention are used.
Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[...
Arena Pharmaceuticals, Inc.
June 08, 2017 - N°20170159088

The present invention relates to processes and intermediates useful in the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid of formula (ia) and salts thereof, an s1p1 receptor modulator that is useful in the treatment of s1p1 receptor-associated disorders, for example, diseases and disorders mediated by lymphocytes, transplant rejection, ...
Autoimmune Disease Patent Pack
Download 255+ patent application PDFs
Autoimmune Disease Patent Applications
Download 255+ Autoimmune Disease-related PDFs
For professional research & prior art discovery
inventor
  • 255+ full patent PDF documents of Autoimmune Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Immunoglobulin variants and uses thereof
Genentech, Inc.
June 08, 2017 - N°20170158773

The invention provides humanized and chimeric anti-cd20 antibodies for treatment of cd20 positive malignancies and autoimmune diseases.
Ip-10 antibodies and their uses
Bristol-myers Squibb Company
June 08, 2017 - N°20170158757

The present invention provides isolated monoclonal antibodies, particularly human antibodies, that bind to ip-10 with high affinity, inhibit the binding of ip-10 to its receptor, inhibit ip-10-induced calcium flux and inhibit ip-10-induced cell migration. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also ...
Novel compounds
Bristol-myers Squibb Company
June 08, 2017 - N°20170158724

And pharmaceutically acceptable salts and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases in which modulation of sting (stimulator of interferon genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases, cancer, pre-cancerous ...
Protein kinase inhibitors
Pharmascience Inc.
June 08, 2017 - N°20170158697

The present invention relates to a novel family of protein kinase inhibitors, more specifically the present invention is directed to inhibitors of the members of the tec or src protein kinase families. The present invention also relates to processes for the preparation of these compounds, to the pharmaceutical composition comprising them, and to their use in the treatment of proliferative, ...
Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
The Walter And Eliza Hall Institute Of Medical Research
June 08, 2017 - N°20170158666

Disclosed are compounds which inhibit the activity of anti-apoptotic bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic bcl-2 protein.
Conjugates of cell binding molecules with cytotoxic agents
The Walter And Eliza Hall Institute Of Medical Research
June 08, 2017 - N°20170157262

A conjugate of a potent cytotoxic agent with a cell-surface receptor binding molecule having a formula (i), wherein t, l, m, n, y, r1, r2, r3, r4, r5, r6, r7, r8, r9, r10, r12, and r13 are defined herein, can be used for targeted treatment of cancer, autoimmune disease, and infectious disease.
Composition using metformin for preventing or treating immune diseases including lupus
Catholic University Industry Academic Cooperation Foundation
June 08, 2017 - N°20170157069

The present invention relates to a composition for preventing or treating immune diseases through the suppression of b cell activity induced by metformin. More particularly, the present invention relates to a composition comprising a metformin compound or a pharmaceutically acceptable salt thereof as an active ingredient for preventing or treating immune diseases, wherein the composition is characterized by suppression or ...
Autoimmune Disease Patent Pack
Download 255+ patent application PDFs
Autoimmune Disease Patent Applications
Download 255+ Autoimmune Disease-related PDFs
For professional research & prior art discovery
inventor
  • 255+ full patent PDF documents of Autoimmune Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Aminopyridazinone compounds as protein kinase inhibitors
Eternity Bioscience Inc.
June 01, 2017 - N°20170152264

The present disclosure provides a compound of formula (i) and the use thereof for the therapeutic treatment of human cancers including b-cell lymphoma and autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis.
Tetrahydroisoquinolinone derivatives and their use in the inhibition of the hsp70 protein
Julius-maximilians-universitaet Wuerzburg
June 01, 2017 - N°20170152229

The present invention relates to tetrahydroisoquinolinone derivatives, a pharmaceutical composition comprising the same and the use of these derivatives in the inhibition of the hsp70 protein. The compounds are useful in the treatment or inhibition of cancer, autoimmune disease, rheumatoid arthritis, inflammatory bowel disease and psoriasis.
Camptothecin conjugates of anti-cd22 antibodies for treatment of b cell diseases
Immunomedics, Inc.
June 01, 2017 - N°20170151356

Disclosed herein are compositions and methods of use comprising combinations of anti-cd22 antibodies with a therapeutic agent. The therapeutic agent may be attached to the anti-cd22 antibody or may be separately administered, either before, simultaneously with or after the anti-cd22 antibody. In preferred embodiments, the therapeutic agent is an antibody or fragment thereof that binds to an antigen different from ...
Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo
Applied Molecular Transport Llc
June 01, 2017 - N°20170151307

The present disclosure relates to pharmaceutical compositions comprising a non-naturally occurring fusion molecule and one or more pharmaceutically acceptable carriers, formulated for oral delivery to a subject, and designed to provide for improved, effective therapies for treatment of, e. G., inflammatory diseases, autoimmune diseases, cancer, metabolic disorders, and growth deficiency disorders.
Use of leukotriene b4 in combination with a toll-like receptor ligand, a rig-i-like receptor ligand, ...
Universite De Laval
June 01, 2017 - N°20170151204

The present invention relates to the use of leukotriene b4 to enhance the response of toll-like receptor (tlr), rig-i-like receptor (rlr), and nod-like receptor (nlr) when stimulated simultaneously with respective proper ligands. The use in combination of ltb4 with those ligands is useful to potentiate immune response for the treatment of autoimmune diseases, immunosuppressive diseases, as well as immunological disorders.
Genetic polymorphisms associated with rheumatoid arthritis, metods of detection and uses thereof
Universite De Laval
May 25, 2017 - N°20170145503

The present invention provides compositions and methods based on genetic polymorphisms that are associated with autoimmune disease, particularly rheumatoid arthritis. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules ...
Use of mcoln-1 modulators to regulate cell migration
Universite De Laval
May 25, 2017 - N°20170145423

The present invention relates to the use of modulators of mcoln-1 for modulating the cells migration, in particular the migration of dendritic cells and tumor cells, especially for antitumoral vaccination, autoimmune diseases treatment, and metastasis prevention.
Inhibitor of bruton's tyrosine kinase
Universite De Laval
May 25, 2017 - N°20170144986

Provided are a compound represented by formula (iii) or pharmaceutically acceptable salts, solvates, active metabolites, polymorphs, esters, tautomers or prodrugs thereof, pharmaceutical compositions containing the compound represented by formula (iii), and the application of the pharmaceutical compositions as selective inreversible inhibitor of bruton's tyrosine kinase for the prevention and treatment of inflammation, autoimmune diseases (such as rheumatoid arthritis) associated with ...
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