Images List Premium Download Classic

Atherosclerosis

Atherosclerosis-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


loading
Inhibitors of trka kinase
Gvk Biosciences Private Limited
January 11, 2018 - N°20180009781

The present invention is directed to the compounds of formula i which are inhibitors of tropomyosin-related kinase a (trka): formula (i) or steroisomers, tautomers or a pharmaceutically acceptable salts, metabolites, isotopes, solvates or prodrugs thereof, wherein, ra, rb, rc, rd, r1, r2, l and het-ar are as defined herein. These compounds can be used for the preventive and/or therapeutic ...
Therapeutic use for alpha1 proteinase inhibitor in hematopoiesis
The Institute For Human Genetics And Biochemistry
January 04, 2018 - N°20180003699

A previously unrecognized fundamental property of α1pi is to regulate the phenotypic composition of circulating and tissue-associated cells derived from hematopoietic stem cells. The present invention comprises screening for various unmodified and modified α1pi's which are useful in the treatment of abnormalities in the number of cells of myeloid or lymphoid lineage that are associated with ...
Fas and drs are novel molecular targets of senescent cells
Bioventures, Llc
January 04, 2018 - N°20180002431

The present invention relates to modulators of fas and drs and their method of use in the treatment and prevention of diseases and pathologies related to accumulation of senescent cells during aging, such as cancer, chronic obstructive pulmonary disease (copd), osteoarthritis, atherosclerosis, neurodegenerative diseases, diabetes, and many others. The present invention also relates to pharmaceutical compositions containing these compounds as ...
Atherosclerosis Patent Pack
Download + patent application PDFs
Atherosclerosis Patent Applications
Download + Atherosclerosis-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Atherosclerosis-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Novel uses
Intra-cellular Therapies, Inc.
January 04, 2018 - N°20180000825

The invention relates to the administration of inhibitors of phosphodiesterase 1 (pde1) for the treatment of diseases or disorders characterized by disruption of or damage to various cgmp/pkg mediated pathways. In one embodiment the invention relates to inhibitors of phosphodiesterase 1 (pde1) for treatment of cardiovascular disease and related disorders, e. G., congestive heart disease, atherosclerosis, myocardial infarction, and stroke.
Nanoparticles for lipid homeostasis
University Of Georgia Research Foundation, Inc.
December 28, 2017 - N°20170367989

Nanoparticles include a polymeric core and a high density lipoprotein (hdl) component where the ratio by weight of the hdl component to the polymeric core is in a range from about 1:9 to about 9:1, such as about 75:25 or less or about 7:3 or less. The nanoparticles may also include a mitochondria targeting moiety. The nanoparticles may be used to treat or prevent ...
High density lipoprotein functionalized magnetic nanostructures
Northwestern University
December 28, 2017 - N°20170367982

Provided herein are compositions and methods for diagnosis and treatment of early-stage atherosclerotic plaques and reduction of plaques in arteries. In particular, provided herein are high-density-lipoprotein-functionalized magnetic nanostructures (hdl-mns) capable of (i) precise anatomic detection of atherosclerotic lesions, (ii) removal of excess cholesterol from macrophage cells in atherosclerotic plaque, and/or (iii) delivery of therapeutic agents to plaque locations, and ...
Atherosclerosis Patent Pack
Download + patent application PDFs
Atherosclerosis Patent Applications
Download + Atherosclerosis-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Atherosclerosis-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and ...
Pimco 2664 Limited
December 07, 2017 - N°20170349551

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted n-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamide compounds (collectively referred to herein as hmc compounds) that are useful, for example, in the treatment of disorders (e. G., diseases) including, inflammation and/or joint destruction ...
Non-cleavable polymer conjugated with alpha v beta 3 integrin thyroid antagonists
Nanopharmaceuticals, Llc
December 07, 2017 - N°20170348425

Chemical compositions and methods of synthesis thereof. The compositions disclosed and described herein are directed toward and classified as anti-angiogenic thyrointegrin antagonists, which may be capable of reacting with one or more cell surface receptors of the integrin αvβ3 receptor family. Anti-angiogenic thyrointegrin antagonists or derivatives thereof are conjugated via a non-cleavable linker having an amine, ...
Method for ameliorating and abating symptoms resulting from rheumatoid arthritis, fibromyalgia, and chronic pain of ...
Honor C.w. M.d., Llc
December 07, 2017 - N°20170348412

The present invention provides a composition and method for treating diseases associated with demyelination of the nerves, such as als, ra, tremors/parkinson's disease, and ms, alzheimer's disease, als, guillain-barre syndrome, atherosclerosis, schizophrenia, tremors/parkinson's disease, senile dementia, muscular dystrophy, attention deficit disorder, attention deficit hyperactivity disorder, complex regional pain syndrome, diabetes, neuropathic pain, spider arthritis west nile virus,, fibromyalgia, ...
Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders
The Johns Hopkins University
December 07, 2017 - N°20170348307

Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases ...
Methods for treating hypercholesterolemia
Ionis Pharmaceuticals, Inc.
November 30, 2017 - N°20170342420

Disclosed herein are antisense compounds and methods for decreasing ldl-c in an individual having elevated ldl-c. Additionally disclosed are antisense compounds and methods for treating, preventing, or ameliorating hypercholesterolemia and/or atherosclerosis. Further disclosed are antisense compounds and methods for decreasing coronary heart disease risk. Such methods include administering to an individual in need of treatment an antisense compound targeted ...
Selective nox-1 inhibitor peptides and uses thereof
Inserm
November 30, 2017 - N°20170340697

The present invention relates to novel peptides, compositions and methods for the prevention and/or treatment of pathological conditions and diseases associated with nadph oxidase 1 (nox1) activity, and/or increased reactive oxygen species (ros) production. The novel peptides are thus particularly useful for treating and/or preventing cancer, atherosclerosis, angiogenesis, and aging.
Composition to enhance hdl cholesterol and to decrease intima-media thickening in animals and humans and ...
Arjuna Natural Extracts, Ltd.
November 23, 2017 - N°20170333507

A method of producing a product to correct hypercholesterolemia including pulping fruits of emblica officinalis with demineralized water to create a slurry. The slurry is treated with pectinase. The pectinase-treated slurry is filtered to create a solution. The solution is concentrated to create a product. A product having an extract of emblica officinalis for prophylactic and for therapeutic treatment of ...
Atherosclerosis Patent Pack
Download + patent application PDFs
Atherosclerosis Patent Applications
Download + Atherosclerosis-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Atherosclerosis-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
A system and method for treating artery
November 23, 2017 - N°20170333131

The present invention provides a system and method for treating artery having atherosclerosis. The system comprises a flexible device for wrapping around the diseased artery, at least an imaging fiber and/or an ablation fiber removably adapted on the inner side of the flexible device for imaging and/or treating the said artery and a controller for controlling the process ...
Detection of activated monocytes in human peripheral blood and determining the concentration of cell surface ...
November 16, 2017 - N°20170328902

Cell surface raman spectroscopy and a quantitative measure of cell surface integrin from monocytes isolated from peripheral blood provide a measure of active inflammation. Patients with elevated lipid profiles and inflammatory status are at high risk for plaque producing atherosclerosis and candidates for aggressive treatment and clinical follow-up.
Novel anti-inflammatory agents
Resveriogix Corp.
November 16, 2017 - N°20170326143

Disclosed are methods of regulating interleukin-6 (il-6) and/or vascular cell adhesion molecule-1 (vcam-1) and methods of treating and/or preventing cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s) by administering a naturally occurring or synthetic quinazolone derivative. The invention provides ...
Probe for detecting atherosclerosis
The Board Of Trustees Of The Leland Stanford Junior University
November 16, 2017 - N°20170325697

A probe device for detecting atherosclerotic plaque may include: an elongate shaft having a proximal end for coupling with a catheter and a distal end; an opening in a side of the shaft; a scintillating window disposed over the opening to form a water tight seal and thus form an imaging window compartment; a 45-degree rotating mirror disposed at least ...
Activated macrophage targetable drug carrier for treatment of atherosclerosis and methods of preparing the same
Korea Basic Science Institute
November 09, 2017 - N°20170319699

Provided is a drug carrier for treatment of atherosclerosis including a biocompatible amphipathic polymer including a macrophage lignad polymer and a hydrophobic substance, and a hydrophobic drug.
Aldose reductase inhibitors and uses thereof
The Trustees Of Columbia University In The City Of New York
November 09, 2017 - N°20170319584

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment ...
High throughput sequencing
October 26, 2017 - N°20170306404

The invention relates to a high throughput method for determining telomere length of mammalian chromosomal dna; primers for use in said method; a kit comprising said primers; use of said method to diagnose or prognose or to determine the risk of developing a telomere shortening disease such as cancer, ageing, neurological disorders including alzheimer's disease, parkinson's disease and other dementias, ...
Anti-endothelial lipase compounds and methods of using the same in the treatment and/or prevention ...
Shifa Biomedical Corporation
October 26, 2017 - N°20170305887

Endothelial lipase (el) inhibitors and methods of using such inhibitors for treating conditions implicating el are provided herein. The present invention meets the needs in the field by providing small molecule inhibitors of el function that can be used therapeutically to raise hdl cholesterol levels in blood, and can be used in the prevention and/or treatment of cholesterol and ...
Loading