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Aspergillosis

Aspergillosis-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Humanized anti-ige antibodies that crosslink cd23 on b lymphocytes but do not sensitize mast cells
Academia Sinica
May 04, 2017 - N°20170121425

A novel humanized anti-ige antibody is disclosed. The antibody is capable of binding to free ige, membrane-bound ige on b lymphocytes, ige bound by cd23, but not to ige bound by high-affinity ige. Fc receptor on mast cells. The present invention relates to the treatment of ige-mediated diseases, including allergic asthma, allergic rhinitis, atopic dermatitis, food allergy, chronic spontaneous (idiopathic) ...
New treatment
Verona Pharma Plc
April 27, 2017 - N°20170112839

The invention provides a compound for use in treating or preventing a disease or condition selected from cystic fibrosis, chronic obstructive pulmonary disease (copd), asthma, mild pulmonary disease, bronchitis, bronchiectasis, idiopathic bronchiectasis, allergic bronchopulmonary aspergillosis, sinusitis, rhinosinusitis, cftr-related metabolic syndrome (crms), pancreatitis, idiopathic chronic pancreatitis and sjörgren's syndrome, or for use in preventing male infertility caused by congenital ...
Diagnosis and treatment of invasive aspergillosis
The Brigham And Women's Hospital, Inc.
April 20, 2017 - N°20170107556

Methods for diagnosing, treating, and monitoring the treatment of invasive aspergillosis (ia) are described. The methods can include detecting the presence of one or more volatile organic compounds (vocs) in the breath of subjects suspected of having ia.
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Diagnosis and treatment of invasive aspergillosis
The Charles Stark Draper Laboratory, Inc.
August 20, 2015 - N°20150233895

Methods for diagnosing, treating, and monitoring the treatment of invasive aspergillosis (ia) are described. The methods can include detecting the presence of one or more volatile organic compounds (vocs) in the breath of subjects suspected of having ia.
Lateral flow device for diagnosing microbial infections
The Johns Hopkins University
July 09, 2015 - N°20150192581

Fungal infections are difficult to diagnose. The most common filamentous fungal infection, aspergillosis, carriers with it a high mortality. Culture of the organism is difficult and obtaining samples, e. G., through a lung biopsy, sometimes causes morbidity. Biomarkers that indicate ‘early’ infection in it development are sought after. One such biomarker is detection of galactomannan (gm), a polysaccharide ...
Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
The Johns Hopkins University
December 11, 2014 - N°20140363506

Formulations are provided for pulmonary administration of an antifungal agent to a patient. Methods of using the formulations in the treatment of antifungal infections are also provided, including treatment of pulmonary aspergillosis with amphotericin b-containing formulations. Methods of manufacturing the formulations to achieve optimum properties are provided as well.
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Methods, compositions, and kits for detection of aspergillosis
The Johns Hopkins University
September 18, 2014 - N°20140274882

Provided herein are methods for detecting an aspergillus protease in a sample, diagnosing a subject with aspergillosis caused by an aspergillus infection based on the presence of an aspergillus protease in a sample, and methods of aspergillosis treatment that incorporate these diagnostic methods. In certain embodiments, the aspergillus protease is asp f2, and the aspergillus infection is caused a. Fumigatus, ...
Methods and composition for testing, preventing, and treating aspergillus fumigatus infection
The Johns Hopkins University
August 28, 2014 - N°20140242085

As a result of the analysis by an sst-rex method so as to identify a target molecule for treating and testing an aspergillus fumigatus infection, a ymaf1 protein has been found out, which is mainly localized in the cell wall of aspergillus fumigatus. Moreover, it has been found out that ymaf1 protein-deficient aspergillus fumigatus has reduced spore-forming ability and pathogenicity. ...
Method of diagnosing and treating an aspergillus species-associated condition
The Johns Hopkins University
June 26, 2014 - N°20140178884

Disclosed herein are methods of diagnosing, monitoring and treating an aspergillus species-associated condition, such as aspergillus fumigatus (af)-associated condition, including aspergillosis, such as invasive aspergillosis (ia). Methods for diagnosing and/or monitoring an aspergillus species-associated condition, such as ia are provided. Also disclosed are point-of-care immunoassays that can be used to diagnose or monitor the efficacy of an aspergillus-associated ...
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