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Arteriosclerosis

Arteriosclerosis-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Use of beta-nicotinamide mononucleotide in preparation of health-care products for preventing and treating arteriosclerosis and ...
Bontac Bio-engineering (shenzhen) Co., Ltd
June 15, 2017 - N°20170165283

A health care product having nicotinamide mononucleotide as the active ingredient, and the use of nicotinamide mononucleotide in preparing health care products for the prevention and treatment of arteriosclerosis and cardiovascular and cerebrovascular diseases caused by arteriosclerosis.
Use of beta-nicotinamide mononucleotide in preparation of drugs for preventing and treating arteriosclerosis and cardio-cerebrovascular ...
Bontac Bio-engineering (shenzhen) Co., Ltd.
June 15, 2017 - N°20170165282

A medication having nicotinamide mononucleotide as the active ingredient, and the use of nicotinamide mononucleotide in preparing medications for the prevention and treatment of arteriosclerosis and cardiovascular and cerebrovascular diseases caused by arteriosclerosis.
Binding inhibitor between tctp dimer type ige-dependent histamine releasing factor and receptor thereof, and use ...
Ewha University - Industry Collaboration Foundation
June 08, 2017 - N°20170158761

The present invention relates to a receptor-binding domain of an ige-dependent histamine releasing factor (hrf), and a use thereof, and more specifically, ascertains, as an hrf structual region, and a fl domain and an h2 domain which bind to a receptor of hrf existing in a cell membrane, ascertains the c-terminus domain of the hrf, and ascertains that a material ...
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Biological-information detecting apparatus, seat with backrest, and cardiopulmonary-function monitoring apparatus
University Of Tsukuba
June 01, 2017 - N°20170150929

A biological-information detecting apparatus includes a first blood-flow measuring device provided at a seat surface of a seat, the first blood-flow measuring device measuring a condition of a blood flow of a popliteal artery of a measurement subject seated in the seat, a second blood-flow measuring device provided at a back of the seat, the second blood-flow measuring device measuring ...
Composition for treating or preventing metabolic disease, containing, as active ingredient, extracellular vesicles derived from ...
Md Healthcare Inc.
March 30, 2017 - N°20170087195

The present invention relates to a pharmaceutical and food composition for treating, preventing, or alleviating a metabolic disease, containing, as an active ingredient, extracellular vesicles derived from akkermansia muciniphila. The composition of the present invention can be used as a pharmaceutical/food composition and the like for treating, preventing, or alleviating metabolic diseases, in particular metabolic diseases such as obesity, ...
Variants of c-type natriuretic peptide
Biomarin Pharmaceutical Inc.
February 23, 2017 - N°20170051033

The present disclosure provides variants of c-type natriuretic peptide (cnp), pharmaceutical compositions comprising cnp variants, and methods of making cnp variants. The cnp variants are useful as therapeutic agents for the treatment of diseases responsive to cnp, including but not limited to bone-related disorders, such as skeletal dysplasias (e. G., achondroplasia), and vascular smooth muscle disorders (e. G., restenosis and ...
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Agent for preventing or ameliorating vascular endothelial malfunction
Kyowa Hakko Bio Co., Ltd.
February 16, 2017 - N°20170042962

An agent for preventing or ameliorating vascular endothelial malfunction and arteriosclerosis-related symptoms caused by the progress of vascular endothelial malfunction (e. G., ischemic diseases such as myocardial infarction, angina, and peripheral artery occlusion) or low blood flow-related symptoms (e. G., stiff shoulders, excessive sensitivity to cold, swelling, erectile dysfunction, rough skin and decrease in exercise performance due to skeletal muscle ...
5-hydroxy-4-(trifluoromethyl)pyrazolopyridine derivative
Daiichi Sankyo Company, Limited
December 29, 2016 - N°20160376267

A compound represented by the general formula (i) or a pharmacologically acceptable salt thereof has an excellent lcat-activating effect and is useful as an active ingredient in a therapeutic or prophylactic agent for arteriosclerosis, arteriosclerotic heart disease, coronary heart disease (including heart failure, myocardial infarction, angina pectoris, cardiac ischemia, cardiovascular disturbance, and restenosis caused by angiogenesis), cerebrovascular disease (including stroke ...
Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders
The Johns Hopkins University
November 24, 2016 - N°20160339019

Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases ...
Dna vaccine containing specific epitope of apolipoprotein (a)
Angesmg, Inc.
October 20, 2016 - N°20160303211

The present invention provides an agent for the treatment or prophylaxis of arteriosclerosis comprising an expression vector encoding a chimeric hepatitis b virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of apolipoprotein (a), wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis b ...
Agent for preventing or ameliorating vascular endothelial malfunction
Kyowa Hakko Bio Co., Ltd.
October 13, 2016 - N°20160296586

An agent for preventing or ameliorating vascular endothelial malfunction and arteriosclerosis-related symptoms caused by the progress of vascular endothelial malfunction (e. G., ischemic diseases such as myocardial infarction, angina, and peripheral artery occlusion) or low blood flow-related symptoms (e. G., stiff shoulders, excessive sensitivity to cold, swelling, erectile dysfunction, rough skin and decrease in exercise performance due to skeletal muscle ...
Continuous arycyclic compound
Mitsubishi Tanabe Pharma Corporation
September 22, 2016 - N°20160272614

This is to provide a continuous arycyclic compound having a dgat1 inhibitory activity, and useful for prophylaxis and/or treatment of obesity or hyperlipidemia caused by obesity, hypertriglyceridemia, lipid metabolism disorder, fatty liver, hypertension, arteriosclerosis, diabetes, etc., as well as to provide a dgat1 inhibitor comprising the continuous arycyclic compound or a pharmaceutically acceptable salt thereof as an effective ingredient. ...
Variants of c-type natriuretic peptide
Biomarin Pharmaceutical Inc.
September 08, 2016 - N°20160256553

The present disclosure provides variants of c-type natriuretic peptide (cnp), pharmaceutical compositions comprising cnp variants, and methods of making cnp variants. The cnp variants are useful as therapeutic agents for the treatment of diseases responsive to cnp, including but not limited to bone-related disorders, such as skeletal dysplasias (e. G., achondroplasia), and vascular smooth muscle disorders (e. G., restenosis and ...
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Cardiovascular disease treatment and prevention
Transdermal Biotechnology, Inc.
July 28, 2016 - N°20160213738

The present invention generally relates to compositions and methods for treatment of subjects having or at risk of arteriosclerosis, hypertension, sickle-cell anemia, or other conditions. In some cases, the composition may include nitric oxide, peptides, or both. The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the ...
Composition for treating hyperlipidemia comprising oxyntomodulin derivative
Hanmi Pharm. Co., Ltd.
July 14, 2016 - N°20160199451

The present invention relates to a composition for preventing or treating hyperlipidemia, fatty liver disease or arteriosclerosis, comprising an oxyntomodulin derivative as an active ingredient. The oxyntomodulin derivative has a high ability to activate glp-1 receptor and glucagon receptor compared to native oxyntomodulin and has the effects of reducing the blood total cholesterol, low-density cholesterol and triglyceride levels that were ...
Cardiovascular disease treatment and prevention
Transdermal Biotechnology, Inc.
June 09, 2016 - N°20160158372

The present invention generally relates to compositions and methods for treatment of subjects having or at risk of arteriosclerosis, hypertension, sickle-cell anemia, or other conditions. In some cases, the composition may include nitric oxide, peptides, or both. The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the ...
Prevention and treatment of cardiovascular diseases using systems and methods for transdermal nitric oxide delivery
Transdermal Biotechnology, Inc.
June 09, 2016 - N°20160158276

The present invention generally relates to compositions and methods for treatment of subjects having or at risk of arteriosclerosis, hypertension, sickle-cell anemia, or other conditions. In some cases, the composition may include nitric oxide. The nitric oxide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, ...
Method for increasing bio-derived low molecular weight compound
Hakuju Institute For Health Science Co., Ltd.
May 19, 2016 - N°20160136448

The present invention is aimed to scientifically examine a change of a living body by exposing the living body in an electric field generated by a high voltage (such an action will be hereinafter also referred to “electric field exposure”), elucidate a detailed mechanism of action of a therapeutic effect by a potential therapeutic device, and ...
Method for risk stratification in stable coronary artery disease
B.r.a.h.m.s Gmbh
May 12, 2016 - N°20160131664

An in vitro method for the risk stratification of patients with stable arteriosclerosis, especially stable coronary artery disease, is disclosed wherein the concentration of procalcitonin is determined in the circulation of such patients using a highly sensitive pct assay, and wherein within the range of pct concentrations in the typical normal range of healthy individuals cutoff values are defined which ...
Composition comprising xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses ...
B.r.a.h.m.s Gmbh
April 14, 2016 - N°20160101121

This invention provides compositions, methods and process of producing extracts from xanthoceras sorbifolia. The extract comprises alkaloids, coumarins, saccharides, proteins, polysaccharides, glycosides, saponins, tannins, acid, flavonoids and others. The composition can be used for treating cancer, arthritis, rheumatism, poor circulation, arteriosclerosis, raynaud's syndrome, angina pectoris, cardiac disorder, coronary heart disease, headache, dizziness, kidney disorder, impotence and premature ejaculation; for preventing ...
Monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase
Shionogi & Co., Ltd.
January 14, 2016 - N°20160009819

Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
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