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Antibodies patents



      
           
This page is updated frequently with new Antibodies-related patent applications. Subscribe to the Antibodies RSS feed to automatically get the update: related Antibodies RSS feeds. RSS updates for this page: Antibodies RSS RSS


Avian derived antibodies

Assembly of bispecific antibodies

Date/App# patent app List of recent Antibodies-related patents
11/13/14
20140336365
 Cdr regions of monoclonal antibody that antagonize sphinogosine 1-phosphate and related methods patent thumbnailCdr regions of monoclonal antibody that antagonize sphinogosine 1-phosphate and related methods
Materials and method for treating cancer and screening for anti-neoplastic agents are provided. These materials and methods can include sphingosine 1-phosphate antagonists that bind to sphingosine-1 phosphate receptor subtype 3.
11/13/14
20140336363
 Antibodies against human csf-1r and uses thereof patent thumbnailAntibodies against human csf-1r and uses thereof
The present invention relates to antibodies against human csf-1r (csf-1r antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.. .
11/13/14
20140336362
 Avian derived antibodies patent thumbnailAvian derived antibodies
The invention is drawn to a composition comprising an isolated mixture of cytotoxic anti-cd20 antibody molecules produces in a transgenic avian. The antibody molecules have a heavy chain and a light chain and exhibit an increased level of antibody-dependent cell-mediated cytotoxicity (adcc) as compared to that of anti-cd20 antibody molecules produced by cho cells..
11/13/14
20140336361
 Assembly of bispecific antibodies patent thumbnailAssembly of bispecific antibodies
Described herein are methods for the efficient production of a heteromultimeric protein, such as a bispecific antibody. Heteromultimeric proteins may be capable of specifically binding to more than one target molecule or different epitopes on a single target molecule.
11/13/14
20140336360
 Tyrosine, serine and threonine phosphorylation sites patent thumbnailTyrosine, serine and threonine phosphorylation sites
The invention discloses 155 novel phosphorylation sites identified in carcinoma and leukemia, peptides (including aqua peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.. .
11/13/14
20140336245
 Virus vectors for highly efficient transgene delivery patent thumbnailVirus vectors for highly efficient transgene delivery
The invention provides viral vector formulations and methods of uses thereof for delivery of transgenes or therapeutic nucleic acids to human subjects. The formulations include a vector and suitable amounts of empty capsids, viral genome-containing capsids, or viral capsid proteins which are optionally chemically or structurally modified and which bind to neutralizing anti-aav antibodies thereby reducing or preventing antibody-mediated clearance of the vector, but still allowing the genome-containing (therapeutic) vector to transduce target cells and achieve therapeutic gene transfer..
11/13/14
20140336156
 Antibodies to 25-hydroxyvitamin d2 and d3 and uses thereof patent thumbnailAntibodies to 25-hydroxyvitamin d2 and d3 and uses thereof
Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin d derivative, such as 25-hydroxyvitamin d2 and/or 25-hydroxyvitamin d3, or a 25-hydroxyvitamin d analog, such as a vitamin d-c22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described.
11/13/14
20140336077
 Means and methods for recognizing the development of cardiovascular disease in an individual patent thumbnailMeans and methods for recognizing the development of cardiovascular disease in an individual
A method of recognizing the development of an acute myocardial infarction (ami) process in an individual, wherein the method comprises steps of: profiling specific antibody reactivities or biomarkers associated with ami susceptibility, the profiling comprises steps of: attaching a set of defined antigens to a substrate; obtaining a biological fluid derived specimen from an individual, the specimen containing a specific antibody repertoire; and binding said antibodies of the biological fluid specimen to the attached antigens thereby forming bound antibody antigen complexes; and analyzing results obtained, wherein the presence of the complexes is indicative of ami.. .
11/13/14
20140336070
 Assay buffer, compositions containing the same, and methods of using the same patent thumbnailAssay buffer, compositions containing the same, and methods of using the same
The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.. .
11/13/14
20140336069
 Method of detecting auto-antibodies from patients suffering from rheumatoid arthritis, a peptide and an assay kit patent thumbnailMethod of detecting auto-antibodies from patients suffering from rheumatoid arthritis, a peptide and an assay kit
Peptides useful in determining the presence of autoantibodies in patients suffering from rheumatoid arthritis are disclosed.. .
11/13/14
20140335579
Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms
The present invention relates to polynucleotides from cochliobolus heterostrophus c5, cyanothece sp. Ccy0110, mycocentrospora acerin and hyaloperonospora parasitica, which code for desaturases and which can be employed for the recombinant production of polyunsaturated fatty acids.
11/13/14
20140335563
Stabilized human igg2 and igg3 antibodies
It is intended to provide highly stable variants of human antibody igg2 and igg3 subclasses. The present invention provides an igg heavy chain comprising the constant region of a human igg2 heavy chain having at least a substitution of y for f at the 300th position, l for v at the 309th position, or a for t at the 339th position designated by the eu index of kabat et al.
11/13/14
20140335561
Method for producing phosphoserine incorporated proteins by using seprs mutants and ef-tu mutants
According to the invention, a phosphorylated protein can be produced in an amount of mg per liter using the seprs and ef-tu mutants. Thus, the invention is useful for the production of various phosphorylated proteins, including phosphorylated enzymes, the production of antibodies, the fabrication of protein chips, and cell-based screening for new drug development..
11/13/14
20140335549
Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using elisa assays
The present invention relates to the field of immunology and hyperproliferative diseases. More specifically, the present invention relates to a method of detecting and monitoring therapeutic antibody:antigen complex, soluble antigen and soluble therapeutic antibody, wherein a patient has undergone at least one course of immunotherapy.
11/13/14
20140335544
Method of detecting the presence of an antibody in a sample
Methods for detecting in a sample the presence of an antibody to a conjugate of an antigen associated with a first carrier by a first association are disclosed. The method comprises contacting a conjugate of the antigen associated with a second carrier by a second association with said sample under conditions that allow binding of the antibody to the antigen; and introducing an agent to detect the presence of the antibody bound to said antigen.
11/13/14
20140335543
Antibodies to clostridium difficile spores and uses thereof
The present invention provides antibodies that bind to the endospore of the bacterium clostridium difficile, methods of making such antibodies, and methods of using such antibodies, including methods of detecting c. Difficile endospores..
11/13/14
20140335540
Method of diagnosing bacterial infections using bacterial glycoproteins
The present application provides a method of diagnosing bacterial infections using engineered glycoproteins in an immunoassay. The engineered bacterial glycoproteins used in the immunoassay comprise a bacterial antigen covalently attached to a protein via polysaccharyltransferase (ptase)-mediated glycosylation, wherein the bacterial antigen is selected based on the bacterial infection of interest.
11/13/14
20140335538
Methods of diagnosing als
The invention relates to an epitope protection assay for use in diagnosis, prognosis and therapeutic intervention in diseases, for example, involving polypeptide aggregation, such as prion infections. The methods of the invention first block accessible polypeptide target epitope with a blocking agent.
11/13/14
20140335508
Method for detecting an infection by the hepatitis c virus
The invention relates to a method of in-vitro detection of an infection with a hepatitis c virus (hcv) in a biological sample, comprising the simultaneous detection of the hcv capsid protein, and of an antibody directed against said capsid protein, said method using, for capturing the anti-capsid antibodies, a peptide comprising an antigenic fragment derived from the truncated hcv capsid. The invention also relates to the peptide for capturing the anti-capsid antibodies and the kits comprising it..
11/13/14
20140335107
Anti-cd79b antibodies and immunoconjugates and methods of use
The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.. .
11/13/14
20140335100
Therapy-enhancing glucan
This invention provides a composition comprising an effective amount of glucan capable of enhancing efficacy of antibodies. This invention further provides the above compositions and a pharmaceutically acceptable carrier.
11/13/14
20140335099
Therapeutic human anti-il-1r1 monoclonal antibody
Antibodies that interact with interleukin-1 receptor type 1 (il-1r1) are described. Methods of treating il-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to il-1r1 are described.
11/13/14
20140335098
Method of isolating human antibodies
Provided is a novel method of isolating and producing human antibodies with desired specificity from human b cells. In particular, a method of isolating human antibodies from memory b cells obtained from patients which suffer from a disease which is caused by or involves activation of the immune system, for example autoimmune and inflammatory disorders is described..
11/13/14
20140335096
Anti-glucagon antibodies and uses thereof
Provided are monoclonal antibodies, or antigen-binding fragments thereof, that bind to glucagon. These antibodies are useful in immunoassays of glucagon levels, and/or in vivo, ex vivo or in vitro immunochemical and other imaging methods for detecting glucagon levels, and for diagnostic, prognostic and predictive purposes, and for optimizing therapeutic regimens in patients in which glucagon signaling is implicated in pathogenesis..
11/13/14
20140335095
Compositions and methods related to protein a (spa) antibodies as an enhancer of immune response
The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria.
11/13/14
20140335094
Mammalian cytokines; related reagents and methods
Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided..
11/13/14
20140335093
Pd-1 antibodies and pd-l1 antibodies and uses thereof
The invention relates to pd-1 antibodies and pd-l1 antibodies and uses thereof.. .
11/13/14
20140335092
Compositions and methods for immunization against drug resistant acinetobacter baumannii
The present invention provides vaccine compositions comprising ompa, or antigenic fragments thereof, and related methods of active immunization against a. Baumannii infection.
11/13/14
20140335091
Anti-glucagon receptor antibodies and methods of use thereof
The present invention provides antagonizing antibodies that bind to glucagon receptor and methods of using same. The anti-glucagon receptor antibodies can be used therapeutically to lower glucose levels in blood, and can be in the prevention and/or treatment of glucose-related disorders, including diabetes, hyperglycemia, hyperinsulinemia, impaired fasting glucose, impaired glucose tolerance, dyslipidemia, or metabolic syndrome..
11/13/14
20140335088
Antibodies and vaccines for use in therapeutic and diagnostic methods for alpha-synuclein-related disorders
Methods of treating or delaying onset of a neurodegenerative disorder with α-synuclein pathology in an individual comprise administering an antibody which is produced from a stabilized soluble α-synuclein oligomer and capable of binding a stabilized soluble α-synuclein oligomer, the stabilized soluble α-synuclein oligomer having a lower formation rate to a non-soluble aggregated form than a non-stabilized soluble oligomer of the α-synuclein. The antibody has been collected from a non-human animal to which stabilized soluble α-synuclein oligomer had been administered or has been produced by hybridoma technology, phage display, ribosome display, mammalian cell display or bacterial display, and the disorder with α-synuclein pathology is characterized by deposition of lewy bodies and lewy neurites or is selected from the group consisting of parkinson's disease (pd), dementia with lewy bodies (dlb), the lewy body variant of alzheimer's disease, and multiple system atrophy (msa)..
11/13/14
20140335085
Fusion protein
A new fusion protein which can specifically suppress the autoantibodies, which can effectively prevent or treat the autoimmune disease of autoantibody type, and which can be expressed in an amount sufficient for industrial production. A fusion protein, characterized in that, a protein (x) containing a site recognized by autoantibodies which are a cause of the autoimmune disease of autoantibody type is connected to a protein (a) containing a fragment of the antibody heavy chain constant region which exhibits the antibody-dependent cellular cytotoxicity with a linker peptide (l) consisting of one or more amino acid(s), wherein the protein (x), the linker peptide (l) and the protein (a) are connected in this order by means of peptide bond from n terminal to c terminal..
11/13/14
20140335076
Humanized monoclonal antibodies to hepatocyte growth factor
The present invention is directed toward a humanized neutralizing monoclonal antibody to hepatocyte growth factor, a pharmaceutical composition comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient.. .
11/06/14
20140331366
Influenza hemagglutinin antibodies, compositions and related methods
Antibodies against influenza hemagglutinin, compositions containing the antibodies, and methods of using the antibodies are provided herein.. .
11/06/14
20140331344
Transgenic animals
The present invention relates inter alia to fertile non-human vertebrates such as mice and rats useful for producing antibodies bearing human variable regions, in which endogenous immunoglobulin chain expression has been inactivated.. .
11/06/14
20140331343
Antibodies, variable domains & chains tailored for human use
The invention relates to the provision of antibody therapeutics and prophylactics that are tailored specifically for human use. The present invention provides libraries, vertebrates and cells, such as transgenic mice or rats or transgenic mouse or rat cells.
11/06/14
20140331339
Transgenic non-human assay vertebrates, assays and kits
The invention provides assay vertebrates comprising a human antigen or epitope knock-in for testing antibodies comprising human variable regions and generated in a related antibody-generating vertebrate. The invention also provides kits and methods involving these vertebrates and antibodies.
11/06/14
20140330100
Carbon nanostructure electrochemical sensor and method
Carbon nanostructures may be protected and functionalized using a layer-by-layer method whereby functional groups on the carbon nanostructure surface may be further derivatized to incorporate additional functional moieties. Exemplary moieties include redox mediator molecules, crown ethers, catalysts, boric acids, carbohydrates, oligonucleotides, dna or rna aptamers, peptide aptamers, proteins such as enzymes and antibodies, quantum dots and nanoparticles, cells, cell organelles, or other cellular components.
11/06/14
20140329996
Tissue specific expression of antibodies in chickens
Transgenes encoding exogenous antibodies are stably integrated into donor cells and are present in the somatic tissue of chimeric birds. The transgenes encode exogenous antibodies and are preferably expressed in the oviduct for collection in the egg.
11/06/14
20140329911
Predictive marker of dnmt1 inhibitor therapeutic efficacy and methods of using the marker
Provided herein are methods for predicting efficacy of a dna (cytosine-5)-methyltransferase 1 (dnmt1) inhibitor treatment in a subject having a cancer, methods of identifying a subject having a cancer that is more likely to respond to a dnmt1 inhibitor treatment, and methods of selecting a treatment for a subject having a cancer that include determining a level of sox9 in a sample containing cells from a subject having a cancer. Also provided are methods of treating a subject having a cancer that include selectively administering a dnmt1 inhibitor to a subject having cancer determined to have an elevated level of sox9 in a sample containing cells from the subject compared to a reference level.
11/06/14
20140329711
Histidine engineered light chain antibodies and genetically modified non-human animals for generating the same
A genetically modified non-human animal is provided, wherein the non-human animal expresses an antibody repertoire capable of ph dependent binding to antigens upon immunization. A genetically modified non-human animal is provided that expresses a single light chain variable domain derived from a single rearranged light chain variable region gene in the germline of the non-human animal, wherein the single rearranged light chain variable region gene comprises a substitution of at least one non-histidine encoding codon with a histidine encoding codon.
11/06/14
20140329334
Method for monitoring, diagnosis and/or prognosis of acute kidney injury in early stage
The method and kit of the invention have the advantage to provide a specific, simple and early detection of kidney injury markers that is no possible with the standard methods applied until now. The method and kit of the invention also provide the advantage of identifying the specific structure that is injured in the kidney, since it uses specific antibodies for specific proteins present in specific structures of the kidney..
11/06/14
20140329320
Nanoantibodies, binding chlamydia trachomatis antigen, method for inhibition of infection induced by chlamydia trachomatis
A nanoantibody specifically binding surface antigen of chlamydia trachomatis and having seq id no:2 amino acid sequence is disclosed. A nanoantibody specifically binding surface antigen of chlamydia trachomatis and having seq id no:4 amino acid sequence is disclosed.
11/06/14
20140329312
Method for producing human monoclonal immunoglobulin g antibodies
The present invention a method for producing a human immunoglobulin g (igg) antibody using a prime-boost regime in a bone marrow liver thymic (blt) mouse.. .
11/06/14
20140329310
Activated t cells
Provided are compositions comprising activated t cells and activated t cells armed with bispecific antibodies directed at cancer antigens which are poor responders to alloantigen, and methods of using the compositions to help engraftment and improve anti-tumor effects.. .
11/06/14
20140329279
Compositions for cell culture and methods of using the same
Supplementation of the bioflavonoids such as epigallocatechin gallate, rutin, naringin, or genistein into mammalian cell culture media are shown to be effective in reduction of acidic species variants on recombinant antibodies. The demonstrated reduction in acidic species through the use of bioflavonoids, facilitates the manufacturing of a less heterogeneous product with potential improvements in antibody structure and function..
11/06/14
20140328862
Human immunodeficiency virus neutralizing antibodies and methods of use thereof
The invention provides broadly neutralizing antibodies directed to epitopes of human immunodeficiency virus, or hiv. The invention further provides compositions containing hiv antibodies used for prophylaxis, and methods for diagnosis and treatment of hiv infection..
11/06/14
20140328859
Antibodies and methods for wnt pathway-related diseases
The transmembrane e3 ubiquitin ligases znrf3 and rnf43 are negative regulators of β-catenin and the wnt signaling pathway in eukaryotic cells. The activity of znrf3 can be modulated by antibody binding to its extracellular domain, thus causing an increase in wnt signaling.
11/06/14
20140328857
Novel b7-h3l cell surface antigen and antibodies that bind thereto
The invention provides the identification and characterization of disease and cancer-associated antigen, raag10. The invention also provides a family of monoclonal antibodies that bind to antigen raag10, methods of diagnosing and treating various human cancers and diseases that express raag10..
11/06/14
20140328852
Immunogenic gluten peptides and uses thereof
The invention relates to an immunogenic peptide of eight amino acids that is generated naturally in the intestine of celiac patients by means of the hydrolysis of ingested gluten. In addition, the invention relates to the use of the peptide, or antibodies generated against same, for the in vitro monitoring and/or diagnosis of celiac disease, as well as to the use of such antibodies for the detection of gluten in food.
11/06/14
20140328851
Cholesterol ester transfer protein (cetp) inhibitor polypeptide antibodies for prophylactic and therapeutic anti-atherosclerosis treatments
Herein are described two antibodies that can inhibit cetp-lipoproteins interaction and cetp activity. Presently described are an antibody or fragment thereof capable of specifically binding to an epitope of the n-terminal or c-terminal domains of cetp and methods of using these antibodies for separation, identification, diagnosis and therapy..
11/06/14
20140328849
Anti-crth2 antibodies and methods of use
The invention provides anti-crth2 antibodies and methods of using the same.. .
11/06/14
20140328848
Method for treating metabolic disorders
The present invention relates to compositions comprising anti-actriib antibodies and use thereof for increasing brown fat in vertebrate, including rodents and primates, and particularly in humans without significantly affecting hematological parameters.. .
11/06/14
20140328846
Anti-properdin antibodies
A method of inhibiting alternative complement pathway activation in a mammal includes administering an amount of an antibody and/or fragment thereof that specifically binds to an epitope of the n terminus end of properdin effective to the inhibit alternative complement pathway in the subject.. .
11/06/14
20140328845
Methods for increasing thermogenic adipocytes
In certain aspects, the present invention provides compositions and methods for increasing thermogenic adipocytes (e.g., brown adipocytes or other ucp-1 expressing adipocytes) by administering an antagonist of an actriib signaling pathway. Examples of such antagonists include actriib polypeptides, anti-actriib antibodies, anti-myostatin antibodies, anti-gdf3 antibodies, anti-noda1, anti-activin, and anti-gdf11 antibodies.
11/06/14
20140328843
Combination of fcgammariib-specific antibodies and cd20-specific antibodies and methods of use thereof
The present invention relates to methods of treatment, prevention, management or amelioration of one or more symptoms of diseases or disorders associated with cd20 expression that encompass administration of a combination of: (a) one or more antibodies that specifically bind fcγriib, particularly human fcγriib, with greater affinity than said antibodies bind fcγriia, and (b) one or more antibodies that specifically bind to cd20. Such methods include methods of treating, preventing, managing or ameliorating one or more symptoms of a b cell related disease or disorder or an inflammatory disorder.
11/06/14
20140328841
Anti-ceacam1 recombinant antibodies for cancer therapy
Provided herein are recombinant monoclonal antibodies and antigen-binding portions thereof useful in inhibiting ceacam1 in tumor cells, and methods of their use in anti-tumor proliferation and invasiveness therapies, such as the treatment of cancer, particularly pancreatic cancer.. .
11/06/14
20140328838
Caninised antibodies and method for production of same
A method of producing a non-immunogenic immunoglobulin for administration to a target species is provided wherein the method comprises substituting amino acid residues in framework regions of a donor immunoglobulin with amino acid residues present at a corresponding position in framework regions of at least one immunoglobulin derived from the target species. Also provided are antibodies produced by the method of the invention, including novel humanised and caninised anti-ngf antibodies.
11/06/14
20140328836
Her2/neu-specific antibodies and methods of using same
This invention relates to antibodies that specifically bind her2/neu, and particularly chimeric 4d5 antibodies to her2/neu, which have reduced glycosylation as compared to known 4d5 antibodies. The invention also relates to methods of using the 4d5 antibodies and compositions comprising them in the diagnosis, prognosis and therapy of diseases such as cancer, autoimmune diseases, inflammatory disorders, and infectious disease..
11/06/14
20140328833
Methods for treating cancer using anti-pd-1 antibodies
The present invention provides isolated monoclonal antibodies, particularly human monoclonal antibodies, that specifically bind to pd-1 with high affinity. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also provided.
11/06/14
20140328830
Anti-integrin beta-1 antibody compositions and methods of use thereof
The current invention provides human variable chain framework regions and humanized antibodies comprising the framework regions, the antibodies being specific for integrin β1. The invention also provides methods for utilizing the antibodies, for example to treat diseases such as cancer..
11/06/14
20140328828
Use of therapeutic compositions comprising hyaluronan and therapeutic antibodies
The present invention relates generally to treatment and prophylactic protocols for cellular disease or disorders, such as diseases and disorders associated with abnormal cellular proliferation. More particularly, the present invention provides uses of compositions comprising therapeutic antibodies and hyaluronan in the treatment or prophylaxis of cellular diseases and disorders..
11/06/14
20140328797
Human rhinovirus (hrv) antibodies
The invention provides isolated fully human monoclonal anti-hrv antibodies, as well as method of making and using these antibodies. Anti-hrv antibodies of the invention prevent or treat subjects having hrv-infections, and related diseases, including, but not limited to, the common cold, nasopharyngitis, croup, pneumonia, bronchiolitis, asthma, chronic obstructive pulmonary disease (copd), sinusitis, bacterial superinfection, and cystic fibrosis..
11/06/14
20140328753
Antibodies for molecular imaging of vulnerable plaques in atherosclerosis
Antibodies for molecular imaging of vulnerable plaques in atherosclerosis antibody specifically binding to atherosclerosis lesions for in vivo imaging and methods for in vivo imaging of atherosclerosis lesions in a patient.. .
11/06/14
20140328751
Antibodies that bind ov064 and methods of use therefor
Antibodies and antigen-binding fragments of antibodies that bind ov064 are disclosed. The antibodies bind an extracellular domain of ov064.
11/06/14
20140328750
Antibodies reactive with b7-h3 and uses thereof
The present invention relates to antibodies that are immunoreactive to the mammalian, and more particularly, the human b7-h3 receptor and to uses thereof, particularly in the treatment of cancer and inflammation. The invention thus particularly concerns humanized b7-h3-reactive antibodies that are capable of mediating, and more preferably enhancing the activation of the immune system against cancer cells that are associated with a variety of human cancers..
10/30/14
20140325709
Process for the production of fine chemicals
The present invention relates to a process for the production of fine chemicals in a microorganism, a plant cell, a plant, a plant tissue or in one or more parts thereof. The present invention relates further to a process for the control of the production of fine chemicals in a microorganism, a plant cell, a plant, a plant tissue or in one or more parts thereof.
10/30/14
20140325690
Transgenic non-human assay vertebrates, assays and kits
The invention provides assay vertebrates comprising a human antigen or epitope knock-in for testing antibodies comprising human variable regions and generated in a related antibody-generating vertebrate. The invention also provides kits and methods involving these vertebrates and antibodies.


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Antibodies topics: Antibodies, Recombinant, Nucleic Acid, Nucleic Acids, Polypeptide, Therapeutics, Immunoglobulin, Immunoglobulins, Monoclonal, Radiation Therapy, Desmoplastic, Hypertension, Hypertensive, Immunotherapy, Photodynamic Therapy

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This listing is a sample listing of patent applications related to Antibodies for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Antibodies with additional patents listed. Browse our RSS directory or Search for other possible listings.
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