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Anesthetic

Anesthetic-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Mu-conotoxin peptides and use thereof as a local anesthetic
Activen
August 10, 2017 - N°20170226166

The present invention relates to novel mu-conotoxin peptides, biologically active fragments thereof, combinations thereof and /or variants thereof. The invention also relates to their use in pharmaceutical composition for the treatment or prevention of pain, and their use in the preparation of an anesthetic.
Device for providing a breathing gas flow enriched with anesthetic
Drägerwerk Ag & Co. Kgaa
August 10, 2017 - N°20170224947

A method and device, for enriching a gas flow with an anesthetic, include a gas mixer (1), with gas inlets (2a, 2b) and one or more gas outlets (3a, 3b), and an anesthetic dispenser (4) connected to the one or more gas outlets. The anesthetic dispenser at least partially enriches the gas flow to provide a breathing gas flow enriched with anesthetic ...
Compositions and methods for pain relief without numbness
Drägerwerk Ag & Co. Kgaa
August 10, 2017 - N°20170224726

Methods for providing post-operative pain control or relief, without a medically significant degree of numbness, to a patient are disclosed. Methods include, for example, topically administering a paste or ointment comprising bicarbonate to an area of a patient during a surgical or dental procedure, near completion of a surgical or dental procedure or immediately following a surgical or dental procedure, ...
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New benzodiazepine derivative and use thereof
The Medicines Company
August 03, 2017 - N°20170217965

The present invention relates to a new benzodiazepine derivative, pharmaceutically acceptable salt thereof, preparation method therefor, and use thereof. The benzodiazepine derivative and the pharmaceutically acceptable salt thereof of the present invention have obvious anesthetic effect and low toxicity in body, thereby enhancing the medication safety. The benzodiazepine derivative and the pharmaceutically acceptable salt thereof of the present invention have ...
Stable hydrogel compositions including additives
Allergan Industrie, S.a.s.
August 03, 2017 - N°20170216488

Dermal filler hydrogel compositions, methods of making them, and methods of using them to treat soft tissue conditions, such as wrinkles, are provided. The compositions contain a crosslinked hyaluronic acid-based polymer and one or more additional ingredients, and are stable to sterilization by heat and/or pressure treatment. The additional ingredients include vasoconstrictive agents, antioxidant agents, such as a ascorbic ...
Controlled delivery system
Durect Corporation
August 03, 2017 - N°20170216267

The present invention relates to novel anesthetic compositions containing a non-polymeric carrier material and an anesthetic, where the compositions are suitable for providing a sustained local anesthesia without an initial burst and having a duration for about 24 hours or longer. Certain compositions are also provided that include a first anesthetic and a second anesthetic. In such compositions, the second anesthetic ...
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Neuroactive 19-alkoxy-17-substituted steroids, prodrugs thereof, and methods of treatment using same
Sage Therapeutics, Inc.
July 06, 2017 - N°20170190732

The present disclosure is generally directed to neuroactive 19-alkoxy-17-substituted steroids as referenced herein, and pharmaceutically acceptable salts thereof, for use as, for example, an anesthetic, and/or in the treatment of disorders relating to gaba function and activity. The present disclosure is further directed to pharmaceutical compositions comprising such compounds.
Combined laryno-tracheal anesthetic and stylet device
Guidance Airway Solutions, Llc
June 29, 2017 - N°20170182265

A nozzle received by a patient. The nozzle has at least two portions. A first portion that has an upper end and a lower end in which a central aperture extends between the upper and lower ends of the nozzle. The central aperture terminates at the opening of the lower end of the nozzle. A second portion that has two ...
Silicone-based composition for skin treatment
Cmpd Licensing, Llc
June 29, 2017 - N°20170182167

The present embodiments may relate to topically delivered compounded medications for the treatment of scar tissue, skin disorders, and/or other ailments. In one aspect, a transdermal cream or gel may provide for the effective administration of multiple medications simultaneously. Preferably, a silicone-based gel may be provided as a base composition and may have a non-zero percentage of silicone or ...
Micro-needle device
3m Innovative Properties Company
June 29, 2017 - N°20170181822

The present disclosure provides for a micro-needle device (100, 200, 300, 400) that includes a micro-needle array (102, 202, 302, 402) and a liquid connection port (104, 204, 304, 404). The micro-needle array includes a base (106, 206, 306, 406), a sidewall (108, 208, 308, 408) and a top (110, 210, 310, 410), where the base includes two or more of an elongate micro-needle (112, 212, 312, 412) having an interior surface (114, 214, 314, 414) defining an opening 8116, 216, 316, 416) through the elongate micro-needle. The base has a first major surface (118, 218, 318, 418) and a ...
Micro-needle device
3m Innovative Properties Company
June 22, 2017 - N°20170173316

A micro-needle device (100, 200, 300) for delivering a dental local anesthetic that includes a micro-needle array (102, 202, 302) and a hollow spheroid shaped container (108, 208, 308). The micro-needle array has a base (104, 204, 304)and two or more of an elongate micro-needle (106, 206, 306). The elongate micro-needle has an interior surface (110, 210, 310) defining an opening (112, 212, 312) through the elongate micro-needle and the base has a first major surface (114, 214, 314) and a second major ...
General anesthetics that are not neurotoxic
3m Innovative Properties Company
June 22, 2017 - N°20170173048

The present application discloses the unexpected result that a neuroactive steroid such as b260 can act as a general anesthetic and that it has no neurotoxic side effects such as impairing brain development.
Continuous transversus abdominis plane block
Avent, Inc.
June 15, 2017 - N°20170165450

A kit is provided for performing an ultrasound-guided transversus abdominis plane (tap) procedure. The kit includes a container having a fluid delivery needle with a length and gauge for penetration into a patient's tap. An extension set is included having a distal end that mates with the fluid delivery needle. A sheath is included having a size and length such ...
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Extended duration local anesthetic formulation
Department Of Electrical Engineering, National Changhua University Of Education
June 08, 2017 - N°20170157082

An extended duration anesthetic includes a short duration local anesthetic in a dilute solution and a long duration local anesthetic. The long duration local anesthetic is maintained in a powdered form until the time of administration. Premeasured quantities of the dilute solution and powdered long duration local anesthetic in a kit allow for quick preparation of a solution with desired ...
Device and method for dispensing an anesthetic into a gas stream
Drägerwerk Ag & Co. Kgaa
June 01, 2017 - N°20170151412

A device, for dispensing an anesthetic into a gas stream, has a gas inlet, via which gas to be enriched with anesthetic and coming from a gas source flows in and with a gas outlet, via which gas enriched with anesthetic flows out to a patient port. A heating element, for heating the gas stream, is arranged upstream of an ...
Ester and cholinesterase inhibitor in long-acting nerve block
Drägerwerk Ag & Co. Kgaa
June 01, 2017 - N°20170151207

Pharmaceutical compositions comprising an ester anesthetic and a cholinesterase inhibitor have been found to exhibit surprising and beneficial results in achieving a long-acting nerve block for example when administered to an interfascial plane or a peri-neural location in a subject. Such pharmaceutical compositions may also contain an amide anesthetic. Pharmaceutical compositions and methods of using such compositions as described herein ...
Anesthetic formulation
Drägerwerk Ag & Co. Kgaa
May 25, 2017 - N°20170143740

The present invention relates to compositions and methods for pain reduction, including but not limited to, peripheral nerve blocks.
Treatment using dantrolene
Drägerwerk Ag & Co. Kgaa
May 25, 2017 - N°20170143677

Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for malignant hyperthermia (mh) threatening anesthetic crisis. Once dantrolene can be made immediately available to patients triggered of mh, the anesthesiologist will be able to focus exclusively on the management of the patient's physiologic status in this complex and evolving crisis, ...
Apparatus and method for training local anesthesia techniques in dental applications
Drägerwerk Ag & Co. Kgaa
May 18, 2017 - N°20170140670

A safe needle for instructional use includes a bead affixed to the penetrating needle tip of a dental anesthetic needle. The safe needle allows unlimited practice of pre-invasive technique without the stress and safety issues of using an actual needle.
Blood oxygenator device
Universitätsklinikum Regensburg
May 18, 2017 - N°20170136172

The present invention relates to a blood oxygenator device comprising an equilibration-measurement unit for determining the concentration of an inhalational anesthetic in the blood of a patient, a method of manufacturing such a blood oxygenator device and methods of using such a blood oxygenator device.
Device and method for controlling the release of bioactive and therapeutic agents from an implantable ...
Universitätsklinikum Regensburg
May 11, 2017 - N°20170128632

An implantable medical device for controlling the rate of release of a therapeutic agent is provided. The implantable medical device features at least one non-bioresorbable polymer, and/or at least one bioresorbable polymer, where the bioresorbable polymers have different degrees of hydrophilicity. Further, the implantable medical device incorporates at least one therapeutic agent contained in said at least one of ...
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