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 Anesthetic syringe patent thumbnailAnesthetic syringe
A syringe assembly for dispensing medicine from a cartridge having a diaphragm and a piston opposite the diaphragm. The assembly includes a barrel having a hollow interior, an open proximal end, a closed distal end, and an outlet.
Covidien Lp


 Taste modifiers and therapeutic methods thereof patent thumbnailTaste modifiers and therapeutic methods thereof
Taste modifier products and therapeutic methods for encouraging decrease in high calorie food intake by a person are disclosed. A taste modifier product ingested toy a person may comprise one or more sweetness inhibitors and one or more anesthetics.
Weight Sciences, Llc


 Agent in suppository form for the treatment of haemorrhoids, proctitis and other inflammatory proctological disorders patent thumbnailAgent in suppository form for the treatment of haemorrhoids, proctitis and other inflammatory proctological disorders
The invention relates to a medicinal agent to treat hemorrhoid, proctitis and other inflammatory proctology diseases. Said medicinal agent represents a suppository with a mass of 1.35 to 3.65 g and comprises, as active ingredients, 0.3 to 0.65 g of diosmin, 0.05 to 0.2 g of dexpanthenol, 0.05 to 0.2 g of green tea extract, and, as auxiliary substances, 0.0135 to 0.1825 g of emulsifier and fatty acid glycerides.
Obschestvo S Ogranichennoi Otvetstvennostyu "gemodan"


 Multidrug infusion for pain control patent thumbnailMultidrug infusion for pain control
The present invention relates to a formulation comprising an opioid, a na channel blocker, an alpha2-receptor agonist, an opioid mu or delta receptor competitive antagonist and an intravenous anesthetic and/or a neurologic acting agent for use in pain control and/or cognitive function improvement.. .

 Metal-salen complex compound, local anesthetic and antineoplastic drug patent thumbnailMetal-salen complex compound, local anesthetic and antineoplastic drug
A metal-salen complex compound, which exhibits excellent noninvasiveness and can be efficiently transferred to an affected site, a local anesthetic containing this metal-salen complex compound, and an antineoplastic drug containing this metal-salen complex compound are provided. Regarding the metal-salen complex compound, a metal atom part in each of two molecules of a metal-salen complex or a derivative of the metal-salen complex is dimerized via water, and the metal-salen complex compound is mixed with a base to produce an ointment..
Ihi Corporation


 Stable liquid formulations of volatile gas anesthetics patent thumbnailStable liquid formulations of volatile gas anesthetics
A stable liquid nanoemulsion of a volatile gas anesthetic, such as, isoflurane or sevoflurane, is disclosed which is effective in inducing and maintaining a state of anesthesia and/or general anesthesia in a patent. A method of preparation of stable liquid formulations of volatile gas anesthetics is presented, as well as a method for directly testing the concentration of a volatile gas anesthetic in a stable liquid formulation.
University Of Miami


 Spray-on burn dressing patent thumbnailSpray-on burn dressing
The invention is a class of spray-on burn dressings for use in the treatment of various types of tissue burns, such as burns due to heat, chemicals, or sun exposure. The inventive spray-on dressing is comprised of a film-forming polymer and metal or metal oxide particles.
Advanced First Aid Research Pte. Ltd.


 Treatment using dantrolene patent thumbnailTreatment using dantrolene
Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for malignant hyperthermia (mh) threatening anesthetic crisis. Once dantrolene can be made immediately available to patients triggered of mh, the anesthesiologist will be able to focus exclusively on the management of the patient's physiologic status in this complex and evolving crisis, not on the laborious and time consuming reconstitution process of the rescue agent.
Lyotropic Therapeutics, Inc.


 Pre and post anesthetic cooling device and method patent thumbnailPre and post anesthetic cooling device and method
Thermoelectric anesthetic cooling devices allow for temperature controlled cooling of the skin/epidermis or mucous membrane/mucosa, to alleviate pain associated with medical treatment such as injections and skin ablation applied to the human body. The cooling device comprises a body that efficiently conducts heat away from the thermoelectric section of the device.

 Methods of managing eye pain and compositions related thereto patent thumbnailMethods of managing eye pain and compositions related thereto
This disclosure relates to methods of managing eye pain, for example, due to eye surgery. In certain embodiments, the disclosure relates to methods comprising administering a local anesthetic in combination with a steroid to the space around the eye in a subject in need thereof..
Emory University


Controlled delivery system


The present invention relates to novel anesthetic compositions containing a non-polymeric carrier material and an anesthetic, where the compositions are suitable for providing a sustained local anesthesia without an initial burst and having a duration for about 24 hours or longer. Certain compositions are also provided that include a first anesthetic and a second anesthetic.
Durect Corporation


Propofol formulations with non-reactive container closures


A pre-filled syringe storing an anesthetic is disclosed. The pre-filled syringe includes a container configured to store a liquid anesthetic solution.
Fresenius Kabi Usa, Llc


Nerve block injection systems and methods


According to some embodiments, an injection system configured to deliver at least one nerve block agent, other anesthetic or other fluid to a subject comprises a fluid delivery module configured to receive a fluid container, wherein once secured to the fluid delivery module, the fluid container is configured to engage an actuator of the fluid delivery module, at least one motor coupled to the actuator, wherein the at least one motor is configured to selectively move the actuator to create a positive pressure within the fluid container, a pressure detection assembly in fluid communication with the fluid container, wherein the pressure detection assembly is configured to detect the real-time pressure within the fluid container and the fluid conduit, and a processor configured to regulate at least one aspect of the injection system based on, at least in part, the real-time pressure detected by the pressure detection assembly.. .
Carticept Medical, Inc.


Biocompatible crosslinked hydrogels, drug-loaded hydrogels and methods of using the same


Disclosed are hydrogel compositions formed by the mixture of a tetramethylmethane substituted with one or more polyethylene glycols, and wherein each polyethylene glycol substituent is independently further substituted with one or more electrophilic groups, and a tetramethylmethane substituted with one or more polyethylene glycols, and wherein each polyethylene glycol substituent is independently further substituted with one or more nucleophilic groups. Disclosed are also methods of preparing the above hydrogels.

Instrument for continuous discharge of anesthetic drug


The present invention is directed towards instruments and methods for discharging an anesthetic drug on a continuous basis for use as a nerve block. In accordance with the present invention, a catheter assembly is provided that comprises an electrically conductive wire, a protective sheath and an inflatable balloon.

Methods and compositions for tattoo removal


Methods and formulations for removing a tattoo by using a cell disrupter in combination with a vasodilator, and optionally one or more of an osmotic modifying agent, a chelation agent, and an occlusive modifying agent. Embodiments optionally further include using one or more of an antibiotic, anesthetic, penetration enhancer, excipient, carrier and vehicle..
Biochemics, Inc.


Anesthetic syringe


An improved syringe has an enclosure which holds a carpule, with the enclosure having a first opening and a second opening. A needle is attached at the first opening via luer lock, while a plunger is inserted into the second opening.

Non-anesthetic protective gases in combination with liquid anesthetic agents for organ protection


A method of providing anesthesia and organ-protection to a subject in need thereof comprises co-administering to the subject a non-anesthetic protective gas in an amount effect to provide organ protection, and a liquid anesthetic agent in an amount effective to provide anesthesia, at normobaric conditions.. .

Anesthetic dispensing device


An anesthetic dispensing device (1), to which a carrier gas stream is fed for enriching with anesthetic, has the gas stream split into two partial gas streams, one of which flows through a bypass channel (7) unchanged and the other of which is fed to an evaporation chamber (9), where the partial gas stream is saturated with anesthetic. In a mixing point (6), both partial gas streams are mixed to form an anesthetic gas stream, which leaves the anesthetic dispensing device through the anesthetic gas outlet (4).
Drägerwerk Ag & Co. Kgaa


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The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents


The present invention relates to the use of spinosyns and spinosyn compositions as local anesthetics and antiarrhythmic agents. Advantageously, spinosyns may be used as local anesthetics and/or antiarrhythmic agents with little or no disruption or harm to the host which may be an animal or human..

Dental anesthetic comprising tetracaine and a vasoconstrictor for intranasal administration


The present invention relates to tetracaine based anesthetic formulations and methods of use thereof. The invention further relates to topical formulations of tetracaine and methods of topically anesthetizing body tissues.

Anesthetic evaporator unit


An anesthetic evaporator unit (2) with an anesthetic container (4) for receiving liquid anesthetic, with a gas line (6) with an open-pore, porous line wall (8) for guiding gas and for enriching the gas with anesthetic, and with an anesthetic-guiding wick (10), which extends from an interior space (12) of the anesthetic container (4) to the line wall (8) in order to supply the line wall (8) with anesthetic from the anesthetic container (4). The anesthetic evaporator unit (2) has a heater (14) for heating the gas line (6).

Closed loop anesthetic delivery


A method for delivering a sedation drug comprising administering a drug to a patient while requesting the patient to respond to an instruction, monitoring a patient's bis values, bringing the patient to a level of anesthesia where the patient fails to respond to the request within a predetermined response time, and determining a bis value that coincides with the level of anesthesia corresponding to the failure to respond.. .

Surgical instrument having an integrated local anesthetic delivery system


A surgical instrument includes a handle portion having a distal end, a proximal end, and a substantially hollow body defining a valve chamber therein; a curved incising tube partially housed within the handle portion adjacent the handle portion proximal end, extending a predetermined distance from the handle portion, and in fluid communication with the valve chamber; a local anesthetic inlet tube partially housed within the handle portion adjacent the handle portion distal end, extending a predetermined distance from the handle portion, and in fluid communication with the valve chamber; a local anesthetic delivery actuator disposed on the handle portion, whereby the local anesthetic delivery actuator is selectively operative between opened and closed valve chamber positions.. .

Methods and administering local anesthetic


Apparatus for administering certain nerve blocks includes a sheath constructed from a flexible ultrasound echogenic material, a more rigid introducer/dilator for introducing the sheath into the patient, and an ultrasound echogenic catheter for inserting through the sheath once the distal end of the sheath is in place adjacent the nerve(s) to be blocked and the introducer/dilator has been withdrawn. The catheter has provisions at its proximal end for connecting to a source of local anesthetic.
Avent, Inc.


Citrate resorption of bone as a treatment for spinal stenosis


Spinal stenosis is a common debilitating illness that produces symptoms of neurogenic claudication, radiculopathy and weakness. Present therapies include administration of analgesics, epidural injections of local anesthetic with corticosteroids and decompression laminectomy.

Neural block determination


An apparatus for neural block determination is provided including processing circuitry configured to receive muscle movement measurements, analyze the muscle movement measurements in a frequency domain, and determine an effectiveness of an anesthetic based on the analysis of the muscle movement measurements in the frequency domain.. .
The Johns Hopkins University


Anesthetic evaporator and wick for an anesthetic evaporator


A wick (12) includes a porous molding, which has a plurality of air ducts (26) extending in the vertical direction, a plurality of upper deflection chambers (28), which connect each a first air duct pair (29) of the plurality of air ducts (26) to one another, and a plurality of lower deflection chambers (30), which connect each a second air duct pair (31) of the plurality of air ducts (26) to one another. The two air ducts (26) of the second air duct pairs (31) are each associated with different first air duct pairs (29).
Dragerwerk Ag & Co. Kgaa


Anesthesia station for laboratory animals and determining the organohalogen saturation rate of the filters of such an anesthesia station


Provided herein is an anesthesia station for at least one laboratory animal, including an anesthesia area connected to at least one peripheral receiving the laboratory animal. The anesthesia area is able to supply the peripheral with, halogenated anesthetic gases.
Anesteo


Topical composition and delivery system and its use


The described invention provides a topical delivery system comprising a pharmaceutical composition for application directly to a skin of a subject in need thereof comprising (a) an effective therapeutic amount of an active therapeutic agent; (b) chemical drivers comprising an amino benzoate local anesthetic, ethoxydiglycol and methylsulfonylmethane (msm) that in combination are effective to synergistically deliver the therapeutic agent; and (c) a depot component for keeping the pharmaceutical composition in the skin. Methods for delivering an active therapeutic agent into skin, for keeping it in the skin, for reducing systemic side effects attributable to entry of the active agent into the blood stream, and a method for treating a condition, disease or disorder of skin topically also are described in accordance with the embodiments of the described invention..

Formulations for control and prevention of periodontal and perimplant diseases and other diseases and conditions of the mouth, and supra and sub-gingival delivery methods and systems for such formulations


A chemical formulation that is adapted to be used for the control and prevention of periodontal and perimplant conditions and diseases. The formulation comprises a chemical agent, such as an antibiotic.

Method and corresponding kit for administering a paravertebral block


Apparatus for administering certain nerve blocks includes a sheath constructed from a flexible ultrasound echogenic material, a more rigid introducer/dilator for introducing the sheath into the patient, and an ultrasound echogenic catheter for inserting through the sheath once the distal end of the sheath is in place adjacent the nerve(s) to be blocked and the introducer/dilator has been withdrawn. The catheter has provisions at its proximal end for connecting to a source of local anesthetic.
Avent, Inc.


Methods and administering local anesthetic


Apparatus for administering certain nerve blocks includes a sheath constructed from a flexible ultrasound echogenic material, a more rigid introducer/dilator for introducing the sheath into the patient, and an ultrasound echogenic catheter for inserting through the sheath once the distal end of the sheath is in place adjacent the nerve(s) to be blocked and the introducer/dilator has been withdrawn. The catheter has provisions at its proximal end for connecting to a source of local anesthetic.
Avent, Inc.


Desensitizing drug product


Desensitizing drug products, methods of making desensitizing drug products, and methods of using desensitizing drug products including delivery of desensitizing drug products. In one embodiment, the desensitizing drug products are male genital desensitizers that comprise one or anesthetic agents and one or more melting point depressing agents..
Absorption Pharmaceuticals, Llc


Topical relief cream formulation for allergic reactions to poison ivy, poison oak, poison sumac, minor skin irritations and insect bites


A topical relief cream formulation for allergic reactions to poison ivy, poison oak, poison sumac, minor skin irritations and insect bites through chemical means. The relief cream formulation includes a quantity of zinc acetate, a quantity of zinc oxide, a quantity of pramoxine, a quantity of camphor, and a quantity of menthol suspended in a topical lotion base.

Helmet for anesthesia


A helmet for anesthesia, adapted to keep confined anesthetic gases and to administer them in a non-invasive fashion to a patient laying on an operating table, allowing to provide oxygen and/or anesthetic gases through tubes and fast access to the patient's head in case of emergency is described. The helmet has a lower half-shell and an upper half-shell, the lower half-shell being anatomically shaped to receive and support the nape and the neck of the laying patient, the upper half-shell and the lower half-shell having fastening means for fastening one to the other and being configured to be fitted one to the other and to the neck or torso of the patient to form a substantially airtight enclosure for enclosing head of the patient, at least one inlet port for gas supply and at least one outlet port for gas evacuation being on the lower half-shell and/or the upper half-shell..

Catheter locking solution having antimicrobial and anticoagulation properties


The present invention includes a catheter locking solution having both antimicrobial and anticoagulant properties including a local anesthetic and a viscosifying agent. The local anesthetic of the present invention may be an amino amide; an amino ester; an aminoacylanilide; an aminoalkyl benzoate; an amino carbonate; an n-phenylamidine compound; an n-aminoalkyl amid; an aminoketone, or combinations and mixtures thereof.

Methods for the treatment of premature ejaculation


The invention relates to methods of treating premature ejaculation in a patient in need thereof, wherein the methods comprise administering an effective amount of a solution comprising a local anesthetic and/or ssri, and wherein the solution is injected directly into the penis of the patient. The invention is also related to kits comprising an injection system for physician office/home and/or personal use..

Topical composition for pain relief


The composition comprises 0.5% to 10% by weight of a neuropathic analgesic; 0.5% to 10% by weight of a muscle relaxant; 0.5% to 20% by weight of an anti-inflammatory analgesic; and 0.5% to 10% by weight of an anesthetic.. .

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Drug loaded microspheres for post-operative chronic pain


A microsphere is disclosed. The microsphere includes at least one biodegradable polymer and at least one local anesthetic, wherein about 75% of the at least one local anesthetic is released by about 72 hours and from about 80% to about 90% of the at least one local anesthetic is released by about 120 hours, thereby relieving chronic pain for at least 28 days..
Covidien Lp


Tracheal tubes and methods related thereto


Tracheal tubes capable of delivering local anesthetic to a patient during or after intubation, and methods for making and using the same are described herein.. .

Treatment using dantrolene


Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for malignant hyperthermia (mh) threatening anesthetic crisis. Once dantrolene can be made immediately available to patients triggered of mh, the anesthesiologist will be able to focus exclusively on the management of the patient's physiologic status in this complex and evolving crisis, not on the laborious and time consuming reconstitution process of the rescue agent.
Lyotropic Therapeutics, Inc.


Endopharyngeal airway device and kit and use


A kit for ventilating a patient incapable of normal ventilation with current anesthetic techniques due to a risk for airway obstruction in surgical procedures requiring conscious sedation monitored anesthesia care (mac). Includes a single-lumen endopharyngeal nasal tube with an eye shaped opening at its distal end and a cylindrical proximal end used as an adaptor for anesthetic applications such as positive airway pressure via jackson-reese modified ambu-bag or other various anesthesiology applications.

Intrathecal multidrug infusion for pain control


The present invention relates to an intrathecal (it) formulation comprising an opioid, a na channel blocker, an alpha2-receptor agonist, an opioid mu or delta receptor competitive antagonist and an intravenous anesthetic.. .

Disposable safety anesthetic syringe and the needle hub thereto


The present invention discloses a disposable safety syringe that has a needle hub having an accommodating space therein for various purposes. More specifically, the present invention provides a needle hub, configured to an end of a barrel, wherein the needle hub comprises an internal needle, an external needle and a hub body.

Multi-function dermatological biopsy pen


A method for effecting a dermatological biopsy procedure and a hand-held instrument for use in such procedure. The instrument has a pen-like housing with an aperture and a biopsy site marker.

Excipient compositions for mucoadhesive pharmaceutical compositions including a synergistic combination of amylopectin, pullulan, hyaluronic acid, and xyloglucan


Excipient compositions including a combination of excipients for mucoadhesive pharmaceutical compositions that improve mucoadhesiveness power, as well as release of and adhesion time of suitable active pharmaceutical ingredients (apis) are disclosed. The excipient compositions include an aqueous solution with a synergistic combination of polymers, such as, for example amylopectin, pullulan, hyaluronic acid, and tamarind xyloglucan, among others.
Professional Compounding Centers Of America (pcca)


Method of treating disease by auricular anesthesia of cranial nerves


Methods for treating a variety of diseases that comprises performing auricular anesthesia of various cranial nerves. A pharmaceutical composition is administered to an ear canal of a subject in need of such treatment, the composition including an analgesic and/or at least one anesthetic.

Multi-chamber anesthetic delivery system


The present invention is directed to a multi-chamber delivery system of a topical anesthetic formulation for improving the stability of such anesthetic compositions. Topical anesthetics formulations have long been used for providing analgesia prior to any invasive medical procedure.
Lannett Company, Inc.


Xenon-based anesthetic gas composition usable during an endarterectomy involving the clamping of the carotid artery


A xenon-based anesthetic gas to be used, via inhalation, to maintain or preserve cerebral perfusion during an endarterectomy involving the clamping of the carotid artery in a mammal under general anesthesia. The xenon is preferably used in combination with at least one injectable anesthetic morphine agent such as remifentanil, sulfentanil, fentanyl, and alfentanil.
Air Liquide Santé (international)


Method for relieving chronic pain


The method is for use in a part of a mammal having one or more tender points and comprises a dministering a fluid, by a needleless, pressure-based injector, to substantially all of the tender points in the part. The volume of the fluid that is administered to each of the tender points can be about 0.5 cc.

Method and measuring anesthetic depth using cepstrum technique


The present invention relates to a more accurate method for measuring anesthetic depth compared to existing methods for measuring anesthetic depth by using a cepstrum technique, thereby providing an anesthetic depth at an appropriate time even during sudden changes in anesthetic states. The method for measuring anesthetic depth using the cepstrum technique comprises the steps of: a first characteristic vector extraction portion receiving a first eeg signal as an input signal, calculating with a mel-frequency cepstral coefficient (mfcc), and extracting a first characteristic vector; a second characteristic vector extraction portion receiving, as input signals, a second eeg signal from an anesthetic state and a third eeg signal from a non-anesthetic state, calculating with the mel-frequency cepstral coefficient (mfcc), and extracting a second characteristic vector and a third characteristic vector; and a quantifying portion dividing, into a plurality of sections, an area between two axes of a vector flat surface having the second characteristic vector and the third characteristic vector as the two axes, and quantifying a position of the first characteristic vector within the plurality of sections to output an anesthetic depth index..
Charm Engineering Co., Ltd.


Topical medications for bruises and burns


Topical medications to treat the physical effects of bruises and burns. For bruises, the topical medication preferably includes therapeutically effective amounts of vasoconstrictor, such as phenylephrine hcl usp, an anti-inflammatory, such as arica, and compounding agents.
Meridian Research And Development, Inc.


A topical antiviral composition containing a local anesthetic and making the same


The present invention provides a novel pharmaceutical composition and method of making the same. The composition comprises an effective amount of an antiviral agent and a local anesthetic.
Nal Pharmaceuticals, Ltd.


Dermatological compositions and methods


Dermatological compositions (methods of making and using) that include one or more anesthetic agents and/or one or more anti-inflammatory agents and/or a combination of ammonium, sodium, and potassium salts, preferably of an alpha-hydroxy acid.. .
Upsher-smith Laboratories, Inc.


Anesthetic breathing apparatus having volume reflector unit with controllable penetration


An anesthetic breathing apparatus and system, having a patient circle system for re-breathing exhaled gases by a patient a volume reflector, a fresh gas delivery line, and a gas sensor unit arranged to measure a gas stream upstream a fresh gas connection and downstream said reflector unit. The gas sensor unit provides a signal for detection of a reflector driving gas (rdg) crossing over the volume reflector during inspiration based on at least one property of the gas stream measured by the gas sensor unit.
Maquet Critical Care Ab


Pleural air leak test system


Disclosed are methods, apparatus, and systems useful for detecting leaks in pleural tissue. Also disclosed are methods of detecting and sealing such leaks.
Neomend, Inc.


Devices and methods for sustained treatment of bladder pain and irritative voiding


Devices and methods are provided for treating a patient having bladder pain and/or irritative voiding symptoms. The method includes administering to the patient's bladder lidocaine or another anesthetic agent continuously over a treatment period of 24 hours or more in an amount effective to achieve a therapeutic effect which is sustained beyond the end of the treatment period..
Allergan, Inc.


Method and measuring anesthetic depth


The present invention rapidly reacts to changes in the degree of anesthesia to provide an accurate and timely anesthetic depth measurement result, and a method for measuring anesthetic depth comprises the steps of: an epoch dividing portion generating an epoch signal by dividing a eeg signal into a plurality of numbers based on time units, a coefficient portion extracting a cai calculation value (cai) by calculating the number of points in an epoch having a value higher than an established critical value, a shannon entropy calculating portion extracting a shannon entropy calculation value (shen) by conducting a shannon entropy-calculation from the eeg signal, and a spectra entropy calculating portion extracting a spectra entropy value (spen) by conducting a spectra entropy calculation; an improved shannon entropy extracting portion extracting an improved shannon entropy calculation value (mshen) by multiplying the shannon entropy calculation value (shen) and the spectra entropy calculation value (spen); and a cai extracting portion extracting an anesthetic depth index (mscai) through logical operating of the improved shannon entropy calculation value(mshen) and the cai calculation value (cai).. .
Charm Engineering Co., Ltd.


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Injectable long-acting local anesthetic semi-solid formulations and its compositions


What is disclosed is a semi-solid controlled release pharmaceutical composition containing biocompatible and bioerodible semi-solid lipid matrix incorporating local anesthetics agents to form a semi-solid solution, a method of using the pharmaceutical composition to treat, and a method of making the pharmaceutical composition.. .
Mira Pharma Corporation


Stable compositions comprising heparinoid, acute-acting anesthetic, and buffer


Improved methods for preparing compositions including a heparinoid, an acute-acting anesthetic, and a buffer are described. These methods result in compositions in which the heparinoid and the acute-acting anesthetic are at least 90% stable for one year.
Urigen Pharmaceuticals, Inc.


Composition and compounded therapy


A compounded transdermal cream for the topical administration of a compounded therapy includes a first active agent selected from the group consisting of nabumetone in an amount between approximately 5.0% and approximately 25% by weight of the transdermal cream and amitriptyline in an amount between approximately 0.5% and approximately 4.0% by weight of the transdermal cream; a second active agent comprising a nerve depressant in an amount between approximately 5.0% and 15.0% by weight of the transdermal cream, wherein the nerve depressant is gabapentin; a third active agent comprising a local anesthetic in an amount between approximately 1.0% and approximately 7.0% by weight of the transdermal cream, wherein the local anesthetic comprises lidocaine and prilocaine; and dimethyl sulfoxide (dmso).. .
Cmpd Licensing, Llc


Composition and compounded therapy


A compounded transdermal cream for topical administration of a compounded therapy includes a nerve depressant such as gabapentin in an amount between approximately 5% and 15% by weight of the transdermal cream, an nsaid (non-steroidal anti-inflammatory drug) such as nabumetone in an amount between approximately 5% and approximately 25% by weight of the transdermal cream, a tricyclic antidepressant such as amitriptyline in an amount between approximately 0.5% and approximately 4% by weight of the transdermal cream, a local anesthetic such as lidocaine and prilocaine in an amount between approximately 1% and approximately 7% by weight of the transdermal cream, and dimethyl sulfoxide (dmso).. .
Cmpd Licensing, Llc


Methods of anesthetizing nerve tissue in the trigeminal nerve pathway and medical uses thereof


Provided herein are methods of locally and specifically anesthetizing nerve tissue in the trigeminal nerve pathway and methods of performing a surgical procedure on a subject in need thereof that include intranasally administering (1) a pharmaceutical composition that includes a local anesthetic agent and a mucosal absorption enhancer to a subject in need thereof, where the local anesthetic agent and mucosal absorption enhancer are present in an amount sufficient to anesthetize nerve tissue in the trigeminal nerve pathway upon administration, or (2) a pharmaceutical composition that include a free-base form of a local anesthetic agent, where the free-base form of the local anesthetic agent is present in an amount sufficient to anesthetize nerve tissue in the trigeminal nerve pathway upon administration.. .
Loewi Llc


Compositions and methods for pain relief without numbness


Methods for providing post-operative pain control or relief, without a medically significant degree of numbness, to a patient are disclosed. Methods include, for example, administering bicarbonate to an area of a patient during a surgical or dental procedure, near completion of a surgical or dental procedure or immediately following a surgical or dental procedure, in an area previously administered or containing a regional or local anesthetic, in an amount sufficient to provide the patient with pain control or relief, without a medically significant degree of numbness, for a period of time after the surgical or dental procedure..

Video-guided chest tube insertion system


A chest tube placement apparatus is provided that has an elongate body with a rigid tip that is disposed within the interior of a flexible chest tube and an inflatable member mounted to the body is inflated and the apparatus is then inserted in a prepared location in the chest wall of a patient. The body of the apparatus has at least one axial material transfer channel with a tip port that permits the injection of anesthetic or the aspiration of gases or liquids at the tip.
The Regents Of The University Of California


Pulse-width modulation controlling oxygen concentration in anesthetic machine or ventilator


A pulse-width modulation method for controlling oxygen concentration in an anesthetic machine or in a ventilator, comprising the following steps: step a, with a predetermined time interval as one pulse interval, a processing unit divides a breathing cycle into multiple consecutive pulse intervals; step b, a data calculation unit calculates the average inspiratory flow in a certain time interval on the basis of inspiratory flows in one cycle that are detected by a detecting unit, and then calculates the average oxygen flow of this stage on the basis of the average inspiratory flow; and, step c, a control unit selects a solenoid valve and controls the opening and closing times thereof on the basis of the average oxygen flow as calculated in the previous step to implement control of the oxygen flow for each interval.. .
Beijing Aeonmed Co., Ltd.


Anesthetic compounds and related methods of use


Provided herein are compounds according to formula (i): provided herein is also a pharmaceutical composition comprising a compound according to formula (i) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.. .
The General Hospital Corporation




Anesthetic topics:
  • Anesthetic
  • Anesthesia
  • Anesthetics
  • Pharmaceutically Acceptable Salt
  • Drug Delivery System
  • Local Anesthesia
  • Phase Shift
  • Phase Change Material
  • Evaporation
  • Motor Function
  • Acute Pain
  • Ultrasound
  • Physiological Conditions
  • Physiologic
  • Cosmetic Procedure


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