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This page is updated frequently with new Analogue-related patent applications.




Date/App# patent app List of recent Analogue-related patents
02/04/16
20160036461 
 Sorting decoder patent thumbnailSorting decoder
A sorting decoder captures the rank-order of a set of input analogue signals in the digital domain using simple logic components such as self-timed first state elements, without requiring conventional analogue-to-digital signal converters. The analogue signals are each compared against a monotonic dynamic reference and the resulting comparisons are snapshot by a self-timed first state element for each input signal, or the last member of a sorted collection of input signals, at the time when it reaches the reference signal, so that a different snapshot representing the signal value ranking relative to the other signal values is produced for each input signal.
Kandou Labs S.a.


02/04/16
20160033529 
 Use of akt phosphorylation as a biomarker for prognosing neurodegenerative diseases and treating same patent thumbnailUse of akt phosphorylation as a biomarker for prognosing neurodegenerative diseases and treating same
The present invention relates to uses of a peptide comprising an amino acid sequence selected from the group consisting of seq id no: 1, seq id no: 2, analogues and derivatives thereof, for the treatment of neurodegenerative diseases, such as amyotrophic lateral sclerosis (als). The present invention further provides a method for assessing responsiveness to treatment with the peptide of the invention.
Yeda Research And Development Co. Ltd.


02/04/16
20160032377 
 Modified polymerases for improved incorporation of nucleotide analogues patent thumbnailModified polymerases for improved incorporation of nucleotide analogues
Presented herein are polymerase enzymes for improved incorporation of nucleotide analogues, in particular nucleotides which are modified at the 3′ sugar hydroxyl, as well as methods and kits using the same.. .
Illumina, Inc.


02/04/16
20160032257 
 Agent and  modifying the 5' cap of rna patent thumbnailAgent and modifying the 5' cap of rna
An agent and method for modifying the 5′ cap of rna, for example for the purposes of isolation and analysis. According to one aspect the invention provides modified enzymes, namely modified trimethylguanosine synthases 2 from giardia lamblia (glatgs2), the enzymatic activity of which is changed such that as compared to wild type enzymes the former can use adomet analogues better as cofactors..
UniversitÄt Hamburg


02/04/16
20160031918 
 Photoresponsive nucleotide analogue having photocrosslinking ability patent thumbnailPhotoresponsive nucleotide analogue having photocrosslinking ability
The present invention provides a new photoreactive compound which can be used in technologies for photoreactions of nucleic acid, and also provides a photoreactive crosslinking agent comprising the above photoreactive compound. A photoreactive compound represented by the following formula i can be used..
Japan Advanced Institute Of Science And Technology


02/04/16
20160031795 
 Curcumin analogues as zinc chelators and their uses patent thumbnailCurcumin analogues as zinc chelators and their uses
Wherein α, β, x, y, and r1-r11 are defined herein. This invention also provides a pharmaceutical composition comprising the above compounds, a method of inhibiting the activity and/or levels of a matrix metalloproteinase (mmp), a method of inhibiting the production of a cytokine in a population of cells, a method of inhibiting the production of a growth factor in a population of cells, and a method of inhibiting nfκ-b activation in a population of cells..

02/04/16
20160030358 
 Solid dosage form of coated bisphosphonate particles patent thumbnailSolid dosage form of coated bisphosphonate particles
A solid dosage form comprises coated particles of bisphosphonate or a pharmaceutically acceptable analogue or derivative thereof.. .
Arrow International Limited


02/04/16
20160029643 
 Methods, compounds and compositions for repelling insects and/or arachnids patent thumbnailMethods, compounds and compositions for repelling insects and/or arachnids
The present specification discloses natural repellent compounds, and isomeric forms, structural analogues and derivatives of the said compounds, having repellent activity against mosquitoes and other blood-sucking arthropods, compositions comprising such repellent compounds, methods of screening for such repellent compounds, methods of reducing mosquito bites on an individual and methods of reducing mosquito infestation to a location.. .
National Center For Scientific Research "demokritos"


02/04/16
20160029626 
 Cysteine amino-acid compound (or its analogues) used in the disruption of microbial biofilms when treating or preventing diseases caused by phytopathogenic bacteria known to attack plants of agricultural interest patent thumbnailCysteine amino-acid compound (or its analogues) used in the disruption of microbial biofilms when treating or preventing diseases caused by phytopathogenic bacteria known to attack plants of agricultural interest
“cysteine amino-acid compound (or its analogues) used in the disruption of microbial biofilms by treatment of prevention of diseases generated by phytopathogenic bacteria attacking plants of agricultural interest” represented by an innovative solution within the agriculture sector, where said compound can be used in the pharmacological form, as a drug associated with fertilizer for the combat of bacterial diseases which form microbial biofilms, such as citrus variegated chlorosis (cvc), citric canker', huanlongbing (hlb) disease or ‘greening’, amongst other, which inventive concept, as such, never before completed, resides in the benefit deriving from the cysteine amino-acid, and all of its analogues, in the inhibitory action and progressive disruption of the microbial biofilm thus liberating the nutritive flux and hydration of the root to the upper part of the plant and the subsequent regression of the disease symptoms, with the added advantage that the cysteine amino-acid compound is non-toxic, guaranteeing healthy production of foods by plants of agricultural interest that are totally healthy, without toxic residues in their composition, as well as when said compound is applied there is risk to the environment due to the rapid absorption, notably within the area in which it is applied, where such predicates of disease combat, with the exception of toxic collateral effects still guarantee that the final crop and harvest will have a higher productivity per hectare.. .
Instituto Agronomico De Campinas - Iac


01/28/16
20160028454 
 Method and  facilitating high data rate transmission in the wireless communication patent thumbnailMethod and facilitating high data rate transmission in the wireless communication
A method for a wireless device capable of receiving and transmitting a signal includes receiving a reference signal from a second wireless device through a communication channel, estimating the communication channel, using the reference signal, selecting a pair of an analogue digital converter (adc) quantizer and an input distribution, based on the estimated communication channel, and sending information on the selected input distribution and the adc quantizer to the second wireless device. A wireless device capable of wirelessly receiving and transmitting a signal includes a transceiver configured to receive a reference signal from a second wireless device through a communication channel, and a processor configured to estimate the communication channel, using the reference signal, selecting a pair of an adc quantizer and an input distribution, based on the estimated communication channel, and sending information on the selected input distribution and the adc quantizer to the second wireless device..
Samsung Electronics Co., Ltd.


01/28/16
20160028380 

Signal processing


A method of processing an amplitude-modulated analogue signal at a carrier frequency fc comprises: digitising the analogue signal to produce an input bit stream that represents the amplitude of the analogue signal; generating an in-phase reference bit stream that is synchronous to the carrier frequency fc and represents an in-phase digital reference signal substantially in the form of a sine and/or cosine wave; and multiplying the input bit stream with the in-phase reference bit stream to produce an output bit stream representing the amplitude modulation of the analogue signal.. .
Atlantic Inertial Systems Limited


01/28/16
20160028300 

Inverter assembly without galvanic isolation


Disclosed is an inverter assembly without galvanic isolation, the inverter assembly including a pcb mounted with a power supply circuit unit, an inverter unit, an analogue circuit unit and a controller, a first ground circuit pattern to supply a ground power to the power supply circuit unit and the inverter unit, a second ground circuit pattern to supply the ground power to the analogue circuit unit, a third ground circuit pattern to supply the ground power to the controller, a first bead between the first ground circuit pattern and the second ground circuit pattern to isolate an impedance between the first ground circuit pattern and the second ground circuit pattern, and a second bead between the second ground circuit pattern and the third ground circuit pattern to isolate an impedance between the second ground circuit pattern and the third ground circuit pattern.. .
Lsis Co., Ltd.


01/28/16
20160028028 

Tetradentate platinum (ii) complexes cyclometalated with functionalized phenyl carbene ligands and their analogues


Tetradentate platinum complexes of formulas i and ii suitable for phosphorescent or delayed fluorescent and phosphorescent emitters in display and lighting applications.. .
Arizona Board Of Regents On Behalf Of Arizona State University


01/28/16
20160024574 

Dna sequencing with non-fluorescent nucleotide reversible terminators and cleavable label modified nucleotide terminators


This invention provides a process for sequencing nucleic acids using 3′ modified deoxynucleotide analogues or 3′ modified deoxyinosine triphosphate analogues, and 3′ modified dideoxynucleotide analogues having a detectable marker attached to a base thereof.. .
The Trustees Of Columbia University In The City Of New York


01/28/16
20160024061 

Preparation of 2'-fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives


The present invention provides (i) processes for preparing a 2′-deoxy-2′-fluoro-2′-methyl-d-ribonolactone derivatives, (ii) conversion of intermediate lactones to nucleosides with potent anti-hcv activity, and their analogues, and (iii) methods to prepare the anti-hcv nucleosides containing the 2′-deoxy-2′-fluoro-2′-c-methyl-b-d-ribofuranosyl nucleosides from a preformed, preferably naturally-occurring, nucleoside.. .
Gilead Pharmasset Llc


01/28/16
20160022645 

Desferrithiocin polyether analogues


A salt, hydrate or solvate thereof; and methods and compositions for treating the effects of trivalent metal, i.e., iron, overload.. .

01/28/16
20160022622 

Lipid compositions containing bioactive fatty acids


Provided herein is technology relating to lipid compositions containing bioactive fatty acids and particularly, but not exclusively, to compositions and methods related to the production and use of structured lipid compositions containing sciadonic and/or pinoleic acid alone or in combination with other bioactive fatty acids including, but not limited to, eicosapentaenoic acid, docosahexaenoic acid, conjugated linoleic acid, and non-β-oxidizable fatty acid analogues such as tetradecylthioacetic acid.. .

01/21/16
20160020742 

Method for digitally compensating variations, as a function of temperature, of an electrical quantity of an embedded space radiofrequency telecommunications equipment item


A digital compensation method includes measuring the temperature of the equipment item and applying an analogue control voltage intended to maintain the electrical quantity of the equipment item at a predetermined setpoint value. At each measurement instant, the method includes interrogating look-up tables respectively associated with different setpoint values, then, when the measured temperature is situated between two digital temperature states stored in the look-up tables, creating intermediate digital temperature states situated between the two stored digital temperature states, computing, by interpolation, digital control words corresponding to the intermediate digital temperature states created, and selecting a digital control word, stored or intermediate, corresponding to the measured temperature, then delivering, to at least one of the n individual devices, the analogue control corresponding to the selected digital control word..
Thales


01/21/16
20160015784 

Mic-1 fusion proteins and uses thereof


The invention relates to mic-1 fusion proteins. More specifically it relates to compounds comprising fusion proteins comprising a mic-1 protein or an analogue thereof at the c-terminus of the fusion protein and a functional variant of human serum albumin at the n-terminus of the fusion protein connected via a peptide linker.
Novo Nordisk A/s


01/14/16
20160013835 

Multi-stage equalisation use in telemetry


The present invention relates to inspection apparatus for use in wellbores in the oil and gas industries. In particular the invention relates in general to the field of transmission of data between downhole module in a wellbore and a controlling module at the surface.
E.v. Offshore Limited


01/14/16
20160011014 

Electronic measurement circuit


The present invention concerns an electronic measurement circuit for measuring a physical parameter. The circuit comprises: a measurement sensor comprising two differential mounted capacitors each comprising a fixed electrode, and a common electrode, common to the two capacitors which is arranged to be movable relative to each fixed electrode of the two capacitors in order to alter the capacitive value of each capacitor when the physical parameter is measured.
Em Microelectronic-marin Sa


01/14/16
20160009777 

Glucagon analogues


The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular, the invention provides novel glucagon analogue peptides effective in such methods.
Zealand Pharma A/s


01/14/16
20160008287 

Micronized insulin, micronized insulin analogues, and methods of manufacturing the same


A method of preparing an inhalable insulin suitable for pulmonary delivery includes: dissolving an insulin raw material in an acidic solution to form a dissolved insulin solution; titrating the dissolved insulin solution with a buffer solution to form a suspension comprising micronized insulin particles; and stabilizing the micronized insulin particles.. .
Amphastar Pharmaceuticals Inc.


01/07/16
20160006375 

Device for controlling a nozzle of variable cross-section of an aircraft


The invention relates to a control device of a nozzle of variable cross-section of an aircraft suitable for providing a three-phase ac electrical power supply, the nozzle of variable cross-section comprising one or more movable parts which make it possible to modify the cross-section of the nozzle, the control device comprising a system for regulation of the engine connected to a control element which drives at least one electric motor which by a mechanical transmission system creates the movement of the movable part or parts, wherein the electric motor is configured to use directly the electrical power supply of the aircraft and in that the control element comprises analogue type structure to switch the phases of the electrical power supply to modify the direction of rotation of the electric motor.. .
Airbus Operations (s.a.s.)


01/07/16
20160004900 

Method for forming an image reference device


A method is provided of forming an imaging reference device for a biological material imaging system. A first region is provided in a substrate formed from an optically transmissive material which is an analogue of biological tissue.
Ffei Limited


01/07/16
20160003951 

Device for processing a signal delivered by a radiation detector


The invention relates to a device for processing information delivered by a photon detector, comprising: an analogue circuit for generating a signal comprising a series of pulses, each pulse having an amplitude proportional to the energy freed by an interaction of a photon in the detector; an analogue circuit for determining the instant at which the amplitude of a pulse of the signal is maximal; and an element for capturing the value of the signal at said instant.. .
Commissariat à I'Énergie Atomique Et Aux Énergies Alternatives


01/07/16
20160003880 

Method for measuring a physical parameter and electronic circuit for implementing the same


The physical parameter measurement method is performed using an electronic circuit (1) with a resistive sensor (2). The resistive sensor includes two resistors (r1, r2) mounted in series, whose connection node connected to a moving mass (m), is connected to a first input of an amplifier-comparator (3).
Em Microelectronic-marin Sa


01/07/16
20160002311 

Novel glucagon analogues


The present invention relates to novel peptide compounds which have a protracted profile of action and improved solubility and stability, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity..
Novo Nordisk A/s


01/07/16
20160002273 

Thieno[3,2-d]pyrimidine-6-carboxamides and analogues as sirtuin modulators


Provided herein are novel substituted thieno[3,2-d]pyrimidine-6-carboxamide sirtuin inhibitors and methods of use thereof. The sirtuin inhibitors may be used for inhibiting a sirtuin-mediated biological process, and, e.g.
Glaxosmithkline Llc


01/07/16
20160002193 

Anticancer compounds and process for the preparation thereof


The invention disclosed herein relates to novel peribysin e analogues of general formula-i. Further the invention provides simple, economical and short synthesis of peribysin e and its analogues of formula i, in good yield and purity leading to the identification of more potent cell adhesion inhibitors..
Council Of Scientific And Industrial Research


01/07/16
20160002159 

Perfluoro-tert-butyl hydroxyproline


The present invention provides novel analogues of alpha amino acids, comprising a perfluoro-tert-butyl group, and molecules comprising the novel analogues. Also provided are a wide range of applications of the novel analogues in therapeutics, theranostics and pharmaceuticals as well as in imaging applications.

01/07/16
20160000929 

Polymer conjugate for delivery of a bioactive agent


The presentinvention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from prostaglandin analogues, β-blockers and mixtures thereof.
Polyactiva Pty Ltd


01/07/16
20160000883 

Combination of acylated glucagon analogues with insulin analogues


The invention relates to methods for treating metabolic disorders, including diabetes by using a combination of an acylated glucagon analogue and an insulin analogue. The invention also features a kit that includes an acylated glucagon analogue and an insuline analogue..
Zealand Pharma A/s


01/07/16
20160000796 

Pharmaceutical composition for use in prevention or treatment of cancer


Abacavir, a nucleoside analogue reverse transcriptase inhibitor, has been found to exhibit an anti-cancer activity on atl cells in vitro without inhibiting dna replication of normal cells. Abacavir or a pharmaceutically acceptable derivative thereof is useful as an active ingredient of a pharmaceutical composition for use in the prevention or the treatment of cancer, in particular a cancer whose dna repair system is impaired such as breast cancer or adult t-cell leukemia..
Kyoto University


01/07/16
20160000749 

Method of inhibiting or treating a dengue virus infection with quercetin


The present invention relates to a composition having antiviral activity for prophylaxis or treatment of flavivirus infection or a disease resulting therefrom in humans or animals, characterised in that the composition comprises quercetin, or analogues, or derivatives thereof. The composition may further comprise a pharmaceutically acceptable carrier.
Universiti Malaya


01/07/16
20160000746 

Pharmaceutical compositions and methods for treating age-related macular degeneration with melatonin analogues


Pharmaceutical compositions and methods for treating and/or preventing age-related macular degeneration with melatonin analogues are provided.. .
Takeda Pharmaceutical Company Limited


12/31/15
20150381198 

Apparatus and monitoring electrical current


An apparatus for sensing current of a vehicle battery employs an extended counting analogue-to-digital conversion process to a chopped and amplified voltage appearing across a low ohmic shunt resistor placed between the negative pole of the vehicle's battery and the chassis ground of the vehicle. Gain adjustment control of a programmable gain amplifier by matching the gain to the dynamic range of the adc permits a high dynamic signal sensing..
Freescale Semiconductor, Inc.


12/31/15
20150381185 

Circuit arrangement and calibrating activation signals for voltage-controlled oscillators


In order to develop a circuit arrangement (100) and also a method for calibrating at least one activation signal (vbb) provided for a voltage-controlled oscillator (10) such that the expenditure of energy is as low as possible and the output frequency is as high as possible, it is proposed—that the respective number of clock cycles (n) for at least one calibration oscillator (50) and at least one reference oscillator (30) associated with the calibration oscillator (50) is counted by means of at least one clock cycle counter (70) connected downstream of the calibration oscillator (50) and the reference oscillator (30) and a clock error (de) resulting from the difference between these two numbers of clock cycles (n) is integrated and—that the clock error (de) is converted by means of at least one digital-to-analogue converter (90) connected downstream of the clock counter (70) into analogue tuning signals (vcm, vcm−, vcm+) from which the calibrated activation signal (vbb) is derived.. .
Silicon Line Gmbh


12/31/15
20150376582 

Modified polymerases for improved incorporation of nucleotide analogues


Presented herein are polymerase enzymes for improved incorporation of nucleotide analogues, in particular nucleotides which are modified at the 3′ sugar hydroxyl, as well as methods and kits using the same.. .
Illumina, Inc.


12/31/15
20150376257 

Glucagon analogues


The invention provides materials and methods for promoting weight loss or preventing weight gain and for treating diabetes and associated metabolic disorders. In particular, the invention provides novel glucagon analogue peptide compounds effective in such methods.
Zealand Pharma A/s


12/31/15
20150376254 

Gamma-msh analogues


The present invention provides peptide analogues of γ-msh, comprising the amino acid sequence of human γ-msh, or variants thereof, and having one or two linear amino acid probe(s) in the n- and/or c-terminal part of the peptide.. .
Txp Pharma Gmbh


12/31/15
20150376236 

Peptidomimetics possessing photo-controlled biological activity


The present invention relates to pharmaceutically and/or diagnostically active compounds, in particular peptide analogues (peptidomimetics), which can be reversibly controlled between an active and an inactive state by irradiation with light of different wavelengths. The present invention further relates to an intermediate compound usable in the manufacture of such pharmaceutically and/or diagnostically active compounds, as well as a manufacturing method thereof..
National Taras Shevchenko University Of Kyiv


12/31/15
20150376219 

Selective preparations of purine nucleosides and nucleotides: reagents and methods


A process of regiospecific synthesis of n-9 purine nucleoside analogs in either solution or solid phase synthesis is described. The introduction of the sugar moiety or its analogue on to a 6-heteroarylium purine or its mesomeric betaine so that formation of only the n-9 position regioisomers of the purine nucleoside analogs (either d or l enantiomers) is obtained.

12/31/15
20150376201 

Cortistatin analogues and syntheses thereof


And salts thereof, wherein r1, r2, r3, r4, n, and m are as defined herein; processes for preparing such compounds and intermediates thereto; pharmaceutical compositions comprising such compounds; methods for treating a proliferative disease; methods for treating a disease associated with aberrant angiogenesis; methods for inhibiting angiogenesis; and processes for preparing cortistatin a, j, k, and l, and analogs thereof.. .

12/31/15
20150376197 

Morphan and morphinan analogues, and methods of use


The present application relates to analogues of morphan and morphinan, compositions thereof, and methods for treating a disease or condition comprising administering an effective amount of the compounds or compositions to a subject in need thereof.. .
Alkermes Pharma Ireland Limited


12/31/15
20150374795 

O-glycosylated carboxy terminal portion (ctp) peptide-based insulin and insulin analogues


Compositions and formulations comprising insulin or insulin analogues comprising a carboxy terminal portion (ctp) peptide comprising amino acids 112-188 to 142 of the beta subunit of human chorionic gonadotropin (hcgβ) or a partial variant thereof that includes at least one o-glycosylation site of the ctp peptide, wherein the ctp peptide of the ctp peptide-based insulin or insulin analogue is o-glycosylated are described. In particular embodiments, the o-glycosylated insulin analogues are produced in vivo and in further embodiments, the o-glycosylated ctp-based insulin analogues comprise predominantly mannotriose and mannotetrose o-glycans or predominantly mannose o-glycans..
Indiana University Research And Technology Corporation


12/31/15
20150374704 

Combined systemic and topical treatment of disordered and/or prodromal stage tissue


Compositions and methods for treating disordered and/or prodromal stage tissue infected with by a virus in a mammal by co-administering a systemic anti-virus drug and topically administered anti-infective composition. The systemic anti-virus drug is internally administered and disrupts or inhibits virus replication systemically within the mammal.
Quadex Pharmaceuticals, Llc


12/24/15
20150368314 

Glucagon-like-peptide-2 (glp-2) analogues


Glp-2 analogues are disclosed which comprise one of more substitutions as compared to [hgly2]glp-2 and which improved biological activity in vivo and/or improved chemical stability, e.g., as assessed in in vitro stability assays. More particularly, preferred glp-2 analogues disclosed herein comprise substitutions at one or more of positions 8, 16, 24 and/or 28 of the wild-type glp-2 sequence, optionally in combination with further substitutions at position 2 (as mentioned in the introduction) and one or more of positions 3, 5, 7, 10 and 11, and/or a deletion of one or more of amino acids 31 to 33 and/or the addition of a n-terminal or c-terminal stabilizing peptide sequence.
Zealand Pharma A/s


12/24/15
20150368313 

Novel glucagon analogues


The present invention relates to novel glucagon peptides with improved stability and solubility at neutral ph, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The glucagon peptides of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity..
Novo Nordisk A/s


12/17/15
20150361153 

Insulin analogues with chlorinated amino acids and nucleic acids encoding the same


An insulin analogue comprises a b-chain polypeptide incorporating a chlorinated phenylalanine. The chlorinated phenylalanine may be located at position b24.
Case Western Reserve University


12/17/15
20150361138 

Kiss1r receptor agonist compounds and use thereof for inducing ovulation in mammals


A kiss1r agonist peptide compound capable of inducing ovulation in a female mammal is provided. The compound is a pseudopeptide having the c-terminal sequence: -xaaΨ[tz]xaa2-xaa3-xaa4-nh2 (seq id no: 3), where Ψ[tz] represents a 1,4-disubstituted 1,2,3-triazole group replacing the peptide bond between the xaa1 residue and the xaa2 residue, xaa1 is gly or ala, xaa2 is leu or an aliphatic α-aminoacyl analogue residue, xaa3 is arg, arg(me) or a positively charged α-aminoacyl analogue residue, and xaa4 is tyr, phe, trp or an α-aminoacyl analogue residue such as aryl alanine; or an analogue of the pseudopeptide in which the amide peptide bond between xaa2 and xaa3 and/or between xaa3 and xaa4 is replaced with an isosteric bond, or a salt thereof..
Centre National De La Recherche Scientifique


12/17/15
20150361135 

Polypeptide specifically binding to rare earth nanoparticles and use thereof


The present invention provides a polypeptide able to specifically bind to rare-earth nanoparticles and the use thereof. The polypeptide comprises an amino acid sequence shown by seq id no: 1 or analogues thereof.
University Of Science And Technology Of China


12/17/15
20150359925 

Procoagulant peptides and their derivatives and uses therefor


The present invention is directed to a hemostatic or tissue sealing material having (a) a peptide having a sequence seq id no: 1 or an amino acid analog sequence thereof, and (b) a scaffold for said peptide or amino acid analogue sequence. The scaffold is preferably hemostatic, such as a natural or genetically engineered absorbable polymer, a synthetic absorbable polymer, or combinations thereof.
Ethicon, Inc.


12/17/15
20150359901 

Piperazinyl derivative reduces high-fat diet-induced accumulation of fat in the livers, therapeutically


A method for inhibiting a liver disease is provided. The method includes administering a pharmaceutical composition of one of a piperazine analogue and a piperazine analogue complex to a warm-blooded animal suffering from the liver disease..
Jansfat Biotechnology Co., Ltd.


12/17/15
20150359900 

Conjugates of water soluble polymer-amino acid oligopeptide-drug, preparation method and use thereof


A conjugate of water soluble polymer-amino acid oligopeptide-drug of formula (i) below and a pharmaceutical composition comprising the conjugate are provided. In the conjugate, p is a water soluble polymer; x is a linking group, wherein the linking group links p and a1; each of a1, a2 and a3 is independently same or different amino acid residue or amino acid analogue residue; each of d1 and d2 is independently same or different drug molecule residue; a is 0 or 1; b is an integer of 2-12; c is an integer of 0-7; d is 0 or 1.
Jenkem Technology Co. Ltd., Tianjin Branch


12/17/15
20150359798 

Piperazinyl derivative reduces high-fat diet-induced accumulation of fat in the livers, therapeutically


A method for inhibiting a liver disease is provided. The method includes administering a pharmaceutical composition of one of a piperazine analogue and a piperazine analogue complex to a warm-blooded animal suffering from the liver disease..
Jansfat Biotechnology Co., Ltd.


12/10/15
20150357630 

Prussian blue analogue electrodes without zeolitic water content


A battery is provided with a hexacyanometallate cathode. The battery cathode is made from hexacyanometallate particles overlying a current collector.
Sharp Laboratories Of America, Inc.


12/10/15
20150353621 

N-terminal truncated insulin analogues


An insulin analogue contains a foreshortened b-chain polypeptide lacking residues b1-b3 and optionally contains an additional substitution in the c-terminal b23-b30 segment of the b-chain. The insulin analogue lacking residues b1-b3 may contain substitutions at b28 and/or b29 that confer rapid action and optionally a non-standard substitution at b24.
Case Western Reserve University


12/10/15
20150352219 

Conjugate compounds


The invention relates to sphingoglycolipid analogues and peptide derivatives thereof, which are useful in treating or preventing diseases or such as those relating to infection, atopic disorders, autoimmune diseases or cancer.. .
Callaghan Innovation Research Limited


12/10/15
20150352183 

Laminins, derivatives, and compositions including same and methods for their therapeutic use


In various embodiments, the present disclosure provides a method of treating a subject using laminin or a composition that includes laminin. In one embodiment, the method is used to enhance muscle regeneration, maintenance, or repair in a subject.
Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada


12/03/15
20150349433 

Improvements in and relating to antennas


An optical signal transmission apparatus (1) for a rotating antenna comprising a plurality of optical modulators (6) arranged for receiving a respective plurality of analogue rf signals (5) and for modulating a respective plurality of optical signals therewith to produce a plurality of modulated analogue optical signals (8). A plurality of opto-electrical converters (14) each converts a respective modulated analogue optical signal (13) into an analogue electrical signal.
Bae Systems Plc


12/03/15
20150349338 

Antimony-based anode on aluminum current collector


An electrochemical battery is provided with an aluminum anode current collector and an antimony (sb)-based electrochemically active material overlying the aluminum current collector. The sb-based electrochemically active material may be pure antimony, sb with other metal elements, or sb with non-metal elements.
Sharp Laboratories Of America, Inc.


12/03/15
20150349279 

Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues


Platinum complexes suitable for use as phosphorescent emitters or as delayed fluorescent and phosphorescent emitters having the following structure:. .
Arizona Board Of Regents On Behalf Of Arizona State University


12/03/15
20150346325 

Distance measuring device


The invention relates to an optoelectronic distance measuring device having a transmitting unit having a driver stage for a light source for emitting optical pulses as pulsed-mode-intensity-modulated optical radiation, having a receiving unit for receiving a portion of the optical radiation, said portion being reflected from a target object, and converting it into an electrical reception signal, by means of a photosensitive electrical component. It also has an analogue-digital converter for digitizing the reception signal, and an electronic evaluation unit which is designed in such a way that a distance from the target object can be ascertained on the basis of a signal propagation time using the digitized reception signal..
Vectronix Ag


12/03/15
20150344462 

Irciniastatin analogues


The present invention is directed to irciniastatin analogues. Uses of these analogues also described..
The Trustee Of The University Of Pennsylvania


12/03/15
20150344448 

Highly selective anti-cancer agents targeting non-small cell lung cancer and other forms of cancer


Described herein are analogues of 2-methyl-3-(2-ethynylthiazol-4-yl)cyclopent-2-enol and the corresponding ketone 3-(2-ethynylthiazol-4-yl)-2-methylcyclopent-2-enone, the analogues having terminal alkyne groups at the 2-position of the thiazole ring. These drug-like molecules, referred to as cetzole compounds, are useful to treat non-small cell lung cancer and other forms of cancer.
The University Of Toledo


12/03/15
20150343078 

Targeted sensitization of non-del(5q) malignant cells


Disclosed are molecules for treating non-del(5q) mds that mimic allelic deficiency in del5q mds to sensitize the malignant clones of patient without del(5q). The disclosed molecule contains an inhibitor of cdc25c, an inhibitor of pp2acα, or a combination thereof, and a toll like receptor-9 (tlr9) targeting ligand.
H. Lee Moffitt Cancer Center And Research Institute, Inc.


12/03/15
20150342955 

Combined systemic and topical treatment of disordered tissues


Kits and methods for treating disordered or infected tissue caused by a virus in a mammal involve co-administering a systemic anti-virus drug and topically administered anti-infective composition. The systemic anti-virus drug is internally administered and disrupts or inhibits virus replication systemically within the mammal.
Quadex Pharmaceuticals, Llc


11/26/15
20150339001 

Printed piezoelectric pressure sensing foil


There is provided an sensing device, comprising: a substrate; a sensor ink printed onto the substrate; a conductive polymer ink printed onto the sensor ink; a conductive carbon paste formed on the polymer ink; and a conductive silver ink printed on the conductive carbon paste. There is also provided a sensing device for processing a signal generated by the input device, the sensing device comprising: an operational amplifier to amplify the signal; a filter to filter signal noise from the signal; an adder to apply an offset and attenuation to the signal; a microcontroller comprising an analogue to digital converter to convert the signal into a digital output signal..

11/26/15
20150336993 

Mitochondria-targeted theranostic agents


Mitochondria-targeted theranostic agents and methods of using them diagnostically and therapeutically are disclosed. In particular, the invention relates to theranostic agents comprising f16, or analogues thereof, conjugated to alkyltriphenylphosphonium lipophilic cations, and their uses in medical imaging and treatment of diseases associated with mitochondrial dysfunction, including cancer..
The Board Of Trustees Of The Leland Stanford Junior University


11/26/15
20150336947 

Pyrroloquinoline alkaloids as antimalarial agents and process for the preparation thereof


The patent provides novel compounds with potential anti-malarial activity and process of synthesis thereof. Further, the process for the synthesis of known antimalarial natural products marinoquinazolinone a-f, aplidiopsamine a and their potential antimalarial analogues is disclosed..
Council Of Scientific & Industrial Research


11/26/15
20150336911 

Desferrithiocin polyether analogues


Or a pharmaceutically acceptable salt thereof are useful in treating conditions such as metal overload, oxidative stress, and neoplastic and preneoplastic conditions.. .

11/26/15
20150335715 

Methods and compositions for treating nafld, hepatic steatosis, and sequelae thereof


Provided herein are oral pharmaceutical compositions containing a glp-1 analogue and/or insulin for treating and reducing the incidence of nonalcoholic fatty liver disease (nafld), hepatic steatosis, and sequelae thereof and methods of utilizing same.. .
Oramed Ltd.


11/26/15
20150335575 

Pharmaceutical spray composition comprising a vitamin d analogue and a corticosteroid


The present invention relates to a topical spray composition comprising a biologically active vitamin d derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.. .
Leo Pharma A/s


11/19/15
20150333725 

Impedance matching element for voltage and/or current sensing devices


An impedance matching element is disclosed which can be used for voltage and/or current sensing or indicating devices used in medium voltage systems in order to improve signal integrity of output signals in comparison with known sensing devices. To enhance sensing accuracy and provide higher output signal immunity against interferences and impedance mismatches, the electric field sensor and/or the magnetic field sensor can be connected to the impedance matching element which allows connection to an independent analogue measuring device and is powered from an energy harvester, with an impedance matching electronic board..
Abb Technology Ag


11/19/15
20150333374 

Ionic liquids for solvating cyclic carbonates


A novel ionic liquids that can be used to solvate at cyclic carbonate esters and its halogenated analogues.. .
Nohms Technologies, Inc.


11/19/15
20150332594 

System and memorizing a narrative


The system and method for memorizing a narrative comprises a user interface equipped with common hardware including a pointing device, microphone, and a display. It further comprises an analogue to digital converter for converting analogue speech to digital signals, a comparator for comparing digital signals to a narrative stored and accessible from the main memory of a computing device, and an alert or for alerting a user when the comparison of digital signals to the stored narrative mismatches..

11/19/15
20150331871 

Tape measure with audio recorder


The present invention is a tape measure in combination with a data transceiver, a headset, and a cell phone. The invention includes a data transceiver with a housing that can be mounted to a tape measure, where the housing features numerous selectors including at least one record button and one playback button.

11/19/15
20150329612 

Process for purifying insulin and analogues thereof


A process is described for purifying insulin and insulin analogues that comprises high-pressure liquid chromatography with an acidic cation exchange medium performed under low to moderate pressure at an elevated temperature.. .
Merck Sharp & Dohme Corp.


11/19/15
20150329560 

Hdac inhibitors as anti-cancer agents


Largazole analogues, methods of making the same, and methods of using the same, are described.. .
The University Of Toledo


11/19/15
20150328338 

Chemical model of a neurodegenerative disease, preparation and uses of same


The invention concerns the use of pyridinium furosemide or one of the derivatives, analogues, salts, metabolites, or prodrugs thereof in the preparation of a chemical model of a neurodegenerative disease, preferably parkinson's disease. The invention also concerns the corresponding chemical model and the uses of same, in particular in screening tests for identifying drug candidates..
Universite Paris-est Creteil Val De Marne


11/12/15
20150326242 

Counter, analogue to digital converter including the counter and image sensing device including the analogue to digital converter


A counter includes a sampling unit suitable for sampling a logic state of a least significant bit (lsb) during a counting hold section, the counting hold section is present between first and second ramp sections; and a toggling control unit suitable for, in response to a clock and a sampling signal outputted from the sampling unit, generating the lsb according to a first voltage level of a counting target signal during a second part of the first ramp section and generating the lsb according to a second voltage level of the counting target signal during a first part of the second ramp section.. .
Sk Hynix Inc.


11/12/15
20150325142 

Calorie balance system


A calorie balance system is designed for consumers who are interested in having a proper and adequate diet while monitoring daily activities. Disclosed embodiments enable consumers to be continuously aware of their caloric intake and to compare their caloric intake with current calories expended.

11/12/15
20150322001 

Omega-3 analogues


The present invention relates to new fatty acid analogues and to their use in cancer therapy, including antimetastatic therapy.. .
The University Of Sydney


11/05/15
20150316778 

Analogue parallax barrier


An optical modulation device has an electro-optical cell in which first and second electrodes (3a, 3b) are disposed on a first substrate (1), in electrical contact with a resistive layer (2) disposed on the first substrate. A third electrode (3c) is disposed on a second substrate (5), and an electro-optic material (4) is disposed between the first substrate and the second substrate.
Sharp Kabushiki Kaisha


11/05/15
20150315177 

Substituted quinones or analogues as colouring agents


The invention relates to protein-adhesive dyes, to the preparation thereof and to preparations comprising same, and to a method for colouring keratin-containing fibres, in particular for colouring human hair.. .
Merck Patent Gmbh


11/05/15
20150315114 

Methods of synthesizing a prostacyclin analog


The present invention provides processes for preparing a prostacyclin analogue of formula (i) or a pharmaceutically acceptable salt thereof, wherein r10 is a linear or branched c1-6 alkyl. The processes of the present invention comprise steps that generate improved yields and fewer byproducts than traditional methods.
Cayman Chemical Company Incorporated


11/05/15
20150313919 

Pharmaceutical spray composition comprising a vitamin d analogue and a corticosteroid


The present invention relates to a topical spray composition comprising a biologically active vitamin d derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.. .
Leo Pharma A/s


11/05/15
20150313881 

Therapeutic methods for type i diabetes


The invention relates to the treatment and prevention of type i diabetes. More specifically, the invention relates to compounds that treat or prevent the body's immune system from destroying β-cells (i.e., insulin-producing cells in the pancreatic islets of langerhans) by inhibition of jnk2, selective inhibition of jnk2, or inhibition of the expression of the mapk9 gene or gene product.
University Of Massachusetts


11/05/15
20150313829 

Topical formulations for the prevention and treatment of alopecia and inhibition of hair growth


The present invention discloses formulations for the treatment and prevention of alopecia; the formulations comprise angiotensin-(1-7) and/or their analogues, encapsulated in ultradeformable vesicles prepared from specific combinations of phospholipids and surfactants, which confer efficacy to topical application in the control of hair growth, which indicates their great potential for the prevention and treatment of alopecia. The invention also describes formulations containing a779 mas receptor antagonist of angiotensin-(1-7) and/or their analogues and their use in inhibiting hair growth..
Universidade Federal De Minas Gerais -ufmg


10/29/15
20150312067 

Training signals for egprs mimo transmissions


A network node for an egprs system, arranged to transmit bursts to a receiving node in the egprs system, where a burst comprises a training sequence with training information for use by the receiving node. The network node is arranged to use waveforms as said known training sequences, with the shape of the waveform as such conveying the training information.
Telefonaktiebolaget L M Ericsson (publ)


10/29/15
20150310298 

Device for the hardware detection of local extremes in an image


A device and method for the hardware detection of local edges in an image, comprised of a plurality of elemental cells for mixed signal processing, locally interconnected with each other, comprising in each cell a first switch configured to enable the pre-charging of a condenser at the supply voltage; and where once said condenser is pre-charged, it discharges via a second switch connected to a power source which varies in a monotonically increasing manner with the analogue voltage representing the value of the pixel concerned; and where the value of the pixel is compared asynchronously with the neighbouring pixels of the neighbouring cells via two inverters, a digital nor gate, a digital nand gate, a third and fourth switch and a memory feature to store the result.. .
Conesjo Superior De Investigaciones Científicas (csic)


10/29/15
20150309192 

Reading device and measuring energy and flight time using silicon photomultipliers


This invention is about a readout apparatus and method for time-of-flight and energy measurements with silicon photomultipliers (sipm) coupled to a scintillator. The timing measurement can be as accurate as 50 ps or below, after calibration.
Petsys - Medical Pet Imaging Systems, S.a.


10/29/15
20150307854 

Methods of producing 6-carbon chemicals via coa-dependent carbon chain elongation associated with carbon storage


This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine or 1,6-hexanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a c6 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on coa-dependent elongation enzymes or analogues enzymes associated with the carbon storage pathways from polyhydroxyalkanoate accumulating bacteria..
Invista North America S.á R.l.


10/29/15
20150307569 

Heterogeneous nuclear ribonucleoprotein a2* (hnrnp a2*) and nucleic acid encoding the same


An hnrnp a2* protein, including an amino acid sequence represented by seq id no. 1.
Institute Of Zoology, Chinese Academy Of Sciences


10/29/15
20150307553 

Synthetic analogues of neural regeneration peptides


Embodiments of this invention include synthetic compounds (nrp analogues) of peptides termed neural regeneration peptides (nrps). Nrp analogues are made by substituting amino acids in the native peptide sequence, modifying amino acids chemically, by replacing amino acids with synthetic moieties, by stabilizing β-turns, acetylation of terminal glycine residues or by cyclization.
Curonz Holdings Company Limited


10/29/15
20150306203 

Synthetic peptide-based emergency vaccine against foot and mouth disease (fmd)


Synthetic fmd peptide immunogens and compositions containing the same are disclosed. Methods for detecting, treating, and preventing an fmd infection in an animal using the synthetic fmd peptide immunogens are also disclosed.
United Biomedical, Inc.


10/29/15
20150306182 

Fat loss composition


Disclosed is a fat loss composition comprising a) a prostaglandin f2alpha analogue, such as cloprostenol, or a pharmaceutically acceptable ester or salt thereof; and b) amino acids 176-191 of human growth hormone. Use of the composition in weight loss, weight management and/or slimming is described..



Analogue topics: Carbon Dioxide, Amino Acid, Radio Signal, Inorganic Compounds, Hydrogen Production From Water, Electrolysis, Semiconductor, High Energy, Semiconductor Material, Transmitter, Synchronization, Concurrent, Surfactant, Hyperglycemia, Pharmaceutically Acceptable Salt

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