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This page is updated frequently with new Analogue-related patent applications.




 Equaliser for the intermediate frequency channel of an fmcw fill level sensor patent thumbnailnew patent Equaliser for the intermediate frequency channel of an fmcw fill level sensor
A fmcw fill level sensor comprising an equaliser that equalizes the intermediate frequency signal digitalised by an analogue-digital converter. Equalising is carried out, for example, in the form of convoluting the digitalised intermediate frequency signal by an equalising function in the time domain.
Vega Grieshaber Kg


 Tin-117m somatostatin receptor binding compounds and methods patent thumbnailnew patent Tin-117m somatostatin receptor binding compounds and methods
Tin-117m somatostatin analogues or antagonist are used to treat tumors and symptoms associated with these tumors which express somatostatin receptors, such as gastroenteropancreatic neuroendocrine tumors. The tin-117m somatostatin receptor binding compounds can be administered at a dosage which is effectively apoptotic and not necrotic.
Serene, Llc


 Thieno- and pyrrolopyrimidine analogues as anticancer agents and methods of use thereof patent thumbnailnew patent Thieno- and pyrrolopyrimidine analogues as anticancer agents and methods of use thereof
The present invention provides for the design and synthesis of halogenated thieno- and pyrrolopyrimidine compounds that exhibit cancer proliferation inhibitory activity and the use thereof for cancer treatment.. .
University Of Maryland, Baltimore County


 Recombinant microorganism expressing avermectin analogue and use thereof patent thumbnailnew patent Recombinant microorganism expressing avermectin analogue and use thereof
The present invention relates to a recombinant microorganism expressing avermectin or analogues thereof and construction method thereof, and also relates to a method of producing avermectin or analogues thereof using the recombinant microorganism, and avermectin or analogues thereof obtained using the method. In addition, the present invention further relates to uses of the avermectin or analogues thereof as insecticides.
Zhejiang Hisun Pharmaceutical Co. Ltd


 Quadrature demodulator for a very high bit rate rfid receiver patent thumbnailQuadrature demodulator for a very high bit rate rfid receiver
A quadrature demodulator not requiring analogue mixers. The demodulation is made using a first integrator and a second integrator which are controlled by square logic signals at twice the frequency of the carrier, the received signal being alternatively integrated by the first integrator and the second integrator over periods of time equal to a quarter period of time of the carrier frequency.
Commissariat A L'energie Atomique Et Aux Energies Alternatives


 Short interfering rna (sirna) analogues patent thumbnailShort interfering rna (sirna) analogues
The present invention is directed to novel double-stranded short interfering (sirna) analogues comprising locked nucleic acid (lna) monomers. Such compounds induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as rna interference (rnai).
Roche Innovation Center Copenhagen A/s


 Novel insulin derivatives and the medical uses hereof patent thumbnailNovel insulin derivatives and the medical uses hereof
The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues.
Novo Nordisk A/s


 Stable glucagon analogues and use for treatment of hypoglycaemia patent thumbnailStable glucagon analogues and use for treatment of hypoglycaemia
The invention relates to derivatives of glucagon analogues comprising the substitutions imp1 and his3, a substituent having three to ten negatively charged moieties covalently attached to a side chain of a lysine as well as intermediates and compositions thereof and their use in medicine.. .
Novo Nordisk A/s


 Novel cyp-eicosanoid derivatives patent thumbnailNovel cyp-eicosanoid derivatives
The present invention relates to compounds according to general formula (i) which are analogues of epoxymetabolites produced by cytochrome p450 (cyp) enzymes from omega-3 (n-3) polyunsaturated fatty acids (pufas). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for c the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias..
Board Of Regents, The University Of Texas System


 Derivatives of glp-1 like peptides, and uses thereof patent thumbnailDerivatives of glp-1 like peptides, and uses thereof
The invention relates to derivatives of glp-1 like peptides which are c-terminally extended analogues of native glp-1. The derivatives comprise two side chains, one at a position corresponding to position 42, and one at a position corresponding to position 18, 23, 27, 31, 36, or 38, wherein both positions are when compared to glp-1(7-37).
Novo Nordisk A/s


Cyclic depsipeptide compounds and their uses

The present invention relates to novel cycloundecadepsipeptide compounds and their analogues which bind and inhibit cyclophilins, have reduced immunosuppressive activity and improved physicochemical properties including water solubility. The present invention further relates to pharmaceutical compositions containing said depsipeptide compounds and their analogues for use in the treatment or prevention of diseases and pathologies which may be ameliorated by the inhibition of cyclophilin activity..
Cypralis Limited

Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas

This disclosure concerns the discovery of the use of fenoterol and (r,r)- and (r,s)-fenoterol analogues for the treatment of a tumor expressing a β2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a β2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject..
Sri International

New substituted biphenyl analogues as dual inhibitors of aromatase and sulfatase

These compounds acting as aromatase and sulfatase inhibitors, they are particularly useful for treating pathological conditions or diseases in which aromatase and sulfatase are involved. Moreover, the present invention provides processes for the preparation of these compounds.

Triarylmethane analogs and their use in treating cancers

Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are triphenyl methane analogs.
U.s. Government As Represented By The Department Of Veterans Affairs

Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy

The present disclosure describes the use of sodium channel blockers such as tetrodotoxin or saxitoxin, its analogues/derivatives as well as their acceptable salts, for treating neuropathic pain resulting from chemotherapy. Methods, compositions, dose units and dose forms of tetrodotoxin related to the use are described..
Wex Medical Limited

An indentation device, instrumented measurement system, and a determining the mechanical properties of materials by the indentation method

The instrumented indentation measurement system includes an indentation device, a loading mechanism, a table for the sample, an analogue-digital converter and a computer. Inside a housing of the device there is arranged a holder for a displacement sensor, rigidly connected to the housing.
Ceske Vysoke Uceni Technicke V Praze, Fakulta Strojni

Fagopyritol synthase genes and uses thereof

The present invention relates to an isolated dna molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor is also described.
Cornell Research Foundation, Inc.

Functionally-modified oligonucleotides and subunits thereof

Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3′ and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mrna splice products produces beneficial therapeutic effects..
Sarepta Therapeutics, Inc.

Fagopyritol synthase genes and uses thereof

The present invention relates to an isolated dna molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor is also described.
Cornell Research Foundation, Inc.

Fagopyritol synthase genes and uses thereof

The present invention relates to an isolated dna molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor is also described.
Cornell Research Foundation, Inc.

Fagopyritol synthase genes and uses thereof

The present invention relates to an isolated dna molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor is also described.
Cornell Research Foundation, Inc.

Polymeric biomaterials derived from phenolic monomers and their medical uses

The present invention provides new classes of phenol compounds, including those derived from tyrosol and analogues, useful as monomers for preparation of biocompatible polymers, and biocompatible polymers prepared from these monomeric phenol compounds, including novel biodegradable and/or bioresorbable polymers. These biocompatible polymers or polymer compositions with enhanced bioresorbabilty and processibility are useful in a variety of medical applications, such as in medical devices and controlled-release therapeutic formulations.
Rutgers, The State University Of New Jersey

Imidazothiazole derivatives as modulators of tnf activity

A series of substituted imidazo[2,1-b]thiazole derivatives, and analogues thereof, being potent modulators of human tnfα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.. .
Ucb Biopharma Sprl

Fused tricyclic imidazole derivatives as modulators of tnf activity

A series of fused tricyclic imidazole derivatives, in particular dihydro-1h-cyclopenta[4,5]imidazo[1,2-a]pyridine derivatives, and analogues thereof, being potent modulators of human tnfα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.. .
Ucb Biopharma Sprl

Biologically active insulin derivatives

A first aspect of the invention relates to a single chain insulin analogue comprising: (a) the a-chain of human or animal insulin, or an analogue or derivative thereof; (b) the b-chain of human or animal insulin, or an analogue or derivative thereof; (c) one or more disulfide bonds between said a-chain and said b-chain; and (d) a further covalent link, l, between a functional group of an amino acid in the a-chain and a functional group of an amino acid in the b-chain, at least one of said functional groups being an amino acid side chain functional group. Further aspects of the invention relate to pharmaceutical compositions comprising said single chain insulin derivatives, and therapeutic uses thereof..
Chemical & Biopharmaceutical Laboratories Of Patras S.a.

Rapid action insulin formulations and pharmaceutical delivery systems

The present invention provides rapid-acting insulin and insulin analogue formulations. The invention further provides delivery devices, particularly infusion sets, which allow for the rapid absorption of insulin and insulin analogues, as well as other active agents.
Thermalin Diabetes, Llc

Compositions

The present invention relates to administration of a dinucleoside polyphosphate analogue or a pharmaceutically acceptable salt thereof, topically in a formulation comprising a suitable excipient or using a device for transdermal delivery, and/or combined with a nanoparticle carrier. The present invention also relates to the therapeutic use of such compositions or devices, in particular in the treatment of pain or epilepsy.
Globalacorn Ltd

Antibiotic compounds that inhibit bacterial protein synthesis

An aminoacylation/translation (ait) system based on the protein synthesis system from the pathogen pseudomonas aeruginosa, was used to screen chemical compounds for identifying inhibitors of protein synthesis. This system includes elongation factors: ef-tu, ef-ts and ef-g, aminoacyl trna synthetase (aars) specific for phenylalanine, phers, and ribosomes isolated from cultures of pseudomonas aeruginosa.
Board Of Regents Of The University Of Texas System

Neurodegenerative disorders

A cyclic polypeptide, derivative or analogue thereof, comprising an amino acid sequence derived from the c-terminus of acetylcholinesterase (ach e), or a truncation thereof.. .
Neuro-bio Ltd

Method for producing induced pluripotent cells

The invention relates to a method for producing induced pluripotent stem cells (ips) by culturing somatic cells subjected to a cellular reprogramming method, characterised in that the somatic cells are cultured in the presence of netrin-1 or an analogue of netrin-1 at least at the beginning of the cellular reprogramming method.. .
Institut National De La Sante Et De La Recherche M Edicale (inserm)

Poly-benzimidazole with pyrene and anthracene flourophore

The present invention discloses polymeric ionic liquid (pil) composition comprising a polymer selected from pbi or abpbi and their derivatives or analogues covalently attached to fluorescence moiety selected from poly aromatic hydrocarbons, preferably pyrene or anthracene. Further, the invention discloses a process for preparing said composition with enhanced fluorescence and stability.
Council Of Scientific & Industrial Research

Glycosylated polypeptide and drug composition containing said polypeptide

[problem] to provide a glycosylated polypeptide having affinity to somatostatin receptors and, compared to somatostatins, having improved in-blood stability. [solution] the glycosylated polypeptide is characterized by at least two amino acids in a somatostatin or an analogue thereof being replaced by glycosylated amino acids..
Glytech, Inc.

Linked purine pterin hppk inhibitors useful as antibacterial agents

The disclosure provides linked purine pterin compounds and analogues thereof that are novel hppk inhibitors. The hppk inhibitors described herein are compounds and the pharmaceutically acceptable salts thereof of general formula i: (i).
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services

Use of paricalcitol in the treatment of inflammatory anaemia

The present invention discloses the use of paricalcitol, a synthetic vitamin d analogue, in the treatment of inflammatory anaemia, preferably in combination with erythropoeisis-stimulating agents. The use of paricalcitol in the treatment of said pathology is associated with a reduced requirement for erythropoeisis-stimulating agents, with optimised iron absorption and with an increase in plasma erythropoietin levels in said patients.

Modified polymerases for improved incorporation of nucleotide analogues

The invention relates to modified polymerase enzymes which exhibit improved incorporation of nucleotide analogues bearing substituents at the 3′ position of the sugar moiety that are larger in size than the naturally occurring 3′ hydroxyl group. Also described are methods of using the polymerases to incorporate nucleotides into polynucleotides, particularly in the context of dna sequencing..
Illumina Cambridge Limited

Cosmetic use of dermicidin, or analogues or fragments thereof, for the prevention and/or treatment and diagnosis of oily skin and aesthetic skin disorders associated therewith

Cosmetic or therapeutic, in particular dermatological, use of dermicidin, or analogues or fragments thereof, for preventing the appearance of imperfections, and also for the treatment and diagnosis of acneic skin or acne-prone skin. The subject matter of the present invention is in particular the use of a cosmetic and/or therapeutic, in particular dermatological, composition containing at least one amino acid sequence of dermicidin, or of an analogue or fragment thereof, or of at least one nucleic acid sequence encoding the sequence, for preventing the appearance of imperfections, and also for the treatment and/or prevention and/or diagnosis of acneic and/or oily or acne-prone and/or oily skin.
L'oreal

Analogue-to-digital converter

This application relates to analogue-to-digital converters (adcs). An adc 200 has a first converter (201) for receiving an analogue input signal (ain) and outputting a time encode signal (dt), such as a pulse-width-modulated (pwm) signal, based on input signal and a first conversion gain setting (gin).
Cirrus Logic International Semiconductor Ltd.

Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues

Tetradentate and octahedral metal complexes suitable for use as phosphorescent or delayed fluorescent and phosphorescent emitters in display and lighting applications.. .
Arizona Board Of Regents On Behalf Of Arizona State University

Tetradentate metal complexes containing indoloacridine and its analogues

The complexes are suitable for use as phosphorescent or delayed fluorescent and phosphorescent emitters in display and lighting applications.. .

Hand-gesture-based interface utilizing augmented reality

A system for providing a hand-gesture-based human-to-device interface includes an imaging device configured to record a sequence of still images and a computing device coupled in communication with the imaging device. The computing device includes a processor and a memory coupled to the processor, wherein the processor is configured to analyse the sequence of still images to identify at least one hand gesture made by a user, determine whether or not the at least one hand gesture includes at least one predefined hand gesture, identify an output signal corresponding to the at least one hand gesture, when the at least one hand gesture includes at least one predefined hand gesture, and use the output signal to control a quantity of at least one analogue parameter..
Augumenta Ltd

Detection of autoantibodies reactive with pancreatic islet cell antigenic molecules and/or insulin

A method of screening a sample of body fluid obtained from an animal subject for analyte autoantibodies reactive with one or more antigenic molecules selected from pancreatic islet cell antigenic molecules (gad, 1a2) and insulin, or one or more variants, analogues, derivatives or fragments thereof, and a kit for use in such a method. After addition of the sample one or more complexes comprising [antigenic molecule of first source]-[analyte auto antibody]-[antigenic molecule of second source].
Rsr Limited

Detection of autoantibodies reactive with pancreatic islet cell antigenic molecules and/or insulin

A method of screening a sample of body fluid obtained from an animal subject for analyte autoantibodies reactive with one or more antigenic molecules selected from pancreatic islet cell antigenic molecules (gad, 1a2) and insulin, or one or more variants, analogues, derivatives or fragments thereof, and a kit for use in such a method. After addition of the sample one or more complexes comprising [antigenic molecule of first source]-[analyte auto antibody]-[antigenic molecule of second source].
Rsr Limited

Potent lna oligonucleotides for the inhibition of hif-1a expression

The present disclosure relates to an lna oligonucleotide consisting of a sequence selected from the group consisting of 5′-(tx)gxgxcsasasgscsastscscstxgxt-3′ and 5′-(gx)txtxascstsgscscststscstxtxa-3′, wherein capital letters designate a beta-d-oxy-lna nucleotide analogue, small letters designate a 2-deoxynucleotide, underline designates either a beta-d-oxy-lna nucleotide analogue or a 2-deoxynucleotide, subscript “s” designates a phosphorothioate link between neighbouring nucleotides/lna nucleotide analogues, and subscript “x” designates either a phosphorothioate link or a phosphorodiester link between neighbouring nucleotides/lna nucleotide analogues, and wherein the sequence is optionally extended by up to five 2-deoxynucleotide units. The lna oligonucleotides are useful for modulating the expression of hypoxia-inducible factor-1a (hif-1a), e.g.
Roche Innovation Center Copenhagen A/s

Glucagon-like-peptide-2 (glp-2) analogues

Glp-2 analogues are disclosed which comprise one of more substitutions as compared to h[gly2]glp-2 and which may have the property of an altered glp-1 activity, and their medical use. The analogues are particularly useful for the prophylaxis treatment or ameliorating of the gastro-intestinal associated side effects of diabetes..
Zealand Pharma A/s

Hexadepsipeptide analogues as anticancer compounds

This invention relates to a method of treatment of cancer comprising administering compound of formula (1) or derivatives or pharmaceutically acceptable salts thereof.. .
Piramal Enterprises Limited

Compositions

The invention provides a dinucleoside polyphosphate analogue, or a pharmaceutically acceptable salt thereof, for use as an anticonvulsant and/or seizure suppressant, in particular in the treatment or prevention of (e.g. Juvenile) epilepsy..
Globalacorn Ltd

Composition comprising nor-adrenaline and a net inhibitor for administering to a brain-dead, heart-beating potential organ donor

A composition, an infusion solution, a method for treatment, and a kit for intravascular administration for treatment of a brain-dead, heart-beating, respirated, potential organ donor. The composition has noradrenaline and a net inhibitor for noradrenaline.
Vivoline Medical Ab

Ad converter including a capacitive dac

An ad converter converts an analogue input voltage into a digital value including a most significant bit to a least significant bit. The ad converter includes: a common node; a capacitive dac; a comparator; a successive approximation controller; and an integrator.
Panasonic Intellectual Property Management Co., Ltd.

Glucagon analogues

The invention provides glucagon analogue peptides and their use for promoting weight loss or preventing weight gain, and the treatment of obesity or excess body weight and associated conditions. The compounds may also be used to improve glycemic control and/or for the treatment of diabetes.
Boehringer Ingelheim International Gmbh

Novel glucagon analogues

The present invention relates to novel glucagon peptides, to the use of said glucagon peptides in therapy, to methods of treatment comprising administration of said glucagon peptides to patients in need thereof, and to the use of said glucagon peptides in the manufacture of medicaments. The glucagon peptides of the present invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity..
Novo Nordisk A/s

Synthesis of duocarmycin analogues

A novel fmoc protected duocarmycin subunit and utilisation as a reagent in solid phase protein synthesis methodology. Also provided is a novel method of solid phase peptide synthesis, and in particular a method for the production of novel intermediates and novel monomeric and extended duocarmycin analogues having amino acid substituents..
University Of East Anglia



Analogue topics:
  • Carbon Dioxide
  • Amino Acid
  • Radio Signal
  • Inorganic Compounds
  • Hydrogen Production From Water
  • Electrolysis
  • Semiconductor
  • High Energy
  • Semiconductor Material
  • Transmitter
  • Synchronization
  • Concurrent
  • Surfactant
  • Hyperglycemia
  • Pharmaceutically Acceptable Salt


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